CN108379546A - A kind of privates washing lotion and preparation method thereof - Google Patents
A kind of privates washing lotion and preparation method thereof Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/24—Heavy metals; Compounds thereof
- A61K33/26—Iron; Compounds thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/19—Acanthaceae (Acanthus family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/287—Chrysanthemum, e.g. daisy
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/288—Taraxacum (dandelion)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/489—Sophora, e.g. necklacepod or mamani
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/756—Phellodendron, e.g. corktree
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/78—Saururaceae (Lizard's-tail family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
- A61K36/815—Lycium (desert-thorn)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9068—Zingiber, e.g. garden ginger
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0034—Urogenital system, e.g. vagina, uterus, cervix, penis, scrotum, urethra, bladder; Personal lubricants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/02—Drugs for genital or sexual disorders; Contraceptives for disorders of the vagina
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
Abstract
The invention belongs to technical field of pharmaceuticals, and in particular to a kind of privates washing lotion and preparation method thereof, the raw material group of the washing lotion becomes：Forge actinolitum brevifibrum, purslane ethanol extract, total flavone extract of maniod eibish, ginger, dark plum, Herba Andrographitis, wild chrysanthemum, the root bark of Chinese wolf-berry, hairyvein agrimony, Cortex Phellodendri, cordate houttuynia, kuh-seng, dandelion.It is formed for main component by forging actinolitum brevifibrum and plurality of Chinese extract, nontoxic, without side-effects, faint scent is pleasant, and to Trichomonas vaginalis, pinworm plays the role of obviously inhibiting to kill, and prevents disease, and washing lotion is used for a long time and plays the effect for preventing disease and health care simultaneously.
Description
Technical field
The present invention relates to a kind of technical field of pharmaceuticals, more particularly, to a kind of privates washing lotion and preparation method thereof.
Background technology
Privates pruritus vulvue is a kind of privates subjective symptoms caused by the various different lesions of vulva, it may be possible to due to various
Bacterium causes, and is common frdquently encountered disease, is common to many skin diseases rather than a species specific disease.But it can also betide outer
Cloudy normal person completely.Chinese medicine is referred to as " pruritus ", this disease is generally divided into limit office property, systemic two major classes.Men and women can fall ill, with
Women is common, and pruritus vulvue multidigit can also involve the skin lesions areas such as labia majora, perineum even crissum in clitoris, nymphae.Work as itch
When serious, patient feels restless more, so that influencing live and work.But current drug is for various reasons, can only alleviate and
It palliates the agonizing sufferings, and taking for drug also brings along corresponding side effect, sufferer cannot be solved from basic.
Chinese patent《A kind of traditional Chinese medicine lotion for treating pruritus vulvue》(number of patent application：CN201610788771.0) open
The traditional Chinese medicine lotion for the treatment of pruritus vulvue, with heat-clearing and damp-drying drug, anti-inflammatory analgetic, sterilizing and itch-relieving, activating blood circulation and reducing swelling, the work(for restraining myogenic
Effect, curative for effect, effect is rapid, quick, treats women's pudendal pruritus significant effect, and have no toxic side effect, nonirritant.
But current privates washing lotion drug cannot play the purpose of elimination, and therapeutic effect is unsatisfactory.
Invention content
To solve the above-mentioned problems, the present invention provides a kind of privates washing lotion and preparation method thereof, by forging actinolitum brevifibrum and more
Kind Chinese medical extract is that main component forms, and nontoxic, without side-effects, faint scent is pleasant, and to Trichomonas vaginalis, pinworm has apparent suppression
The effect killed is made, disease is prevented, washing lotion is used for a long time and plays the effect for preventing disease and health care simultaneously.
The present invention can be achieved through the following technical solutions：
A kind of privates washing lotion, is made of the raw material of following parts by weight：Forge 8~13 parts of actinolitum brevifibrum, the extraction of purslane ethyl alcohol
5~10 parts of object, 4~8 parts of total flavone extract of maniod eibish, 1~4 part of ginger, 0.5~1 part of dark plum, Herba Andrographitis 0.1~2.4
Part, 0.2~1 part of wild chrysanthemum, 0.1~1 part of the root bark of Chinese wolf-berry, 0.2~2 part of hairyvein agrimony, 0.2~2 part of Cortex Phellodendri, 0.2~3 part of cordate houttuynia,
0.1~1.8 part of kuh-seng, 0.2~3 part of dandelion.
Preferably, a kind of privates washing lotion, is made of the raw material of following parts by weight：Forge 10~12 parts of actinolitum brevifibrum, purslane
6~8 parts of ethanol extract, 5~7 parts of total flavone extract of maniod eibish, 2~3 parts of ginger, 0.6~0.8 part of dark plum, Herba Andrographitis
1.2~2 parts, 0.4~0.8 part of wild chrysanthemum, 0.3~0.6 part of the root bark of Chinese wolf-berry, 1~1.6 part of hairyvein agrimony, 1~1.6 part of Cortex Phellodendri, cordate houttuynia
1~2 part, 0.6~1.2 part of kuh-seng, 1~2 part of dandelion.
Preferably, a kind of privates washing lotion, is made of the raw material of following parts by weight：Forge 11 parts of actinolitum brevifibrum, purslane ethyl alcohol
7 parts of extract, 6 parts of total flavone extract of maniod eibish, 2.5 parts of ginger, 0.7 part of dark plum, 1.6 parts of Herba Andrographitis, wild chrysanthemum 0.6
Part, 0.5 part of the root bark of Chinese wolf-berry, 1.3 parts of hairyvein agrimony, 1.3 parts of Cortex Phellodendri, 1.5 parts of cordate houttuynia, 0.9 part of kuh-seng, 1.5 parts of dandelion.
Preferably, the preparation method of the purslane ethanol extract is：Take it is dry spend more bacopa monnieri herb, be added
Ethanol solution refluxing extraction 2 times at 75 DEG C of 10 times of amounts 75~80%, each 1.5h merge extracting solution, are condensed into thick paste, cold
It is lyophilized dry, obtains purslane ethanol extract.
Preferably, the preparation method of the total flavone extract of maniod eibish is：It takes sunset abelmoschus flower to clean up, is added 5
The ethanol solution of~10 times of amounts 80%, heating extraction 2~3 times, extracts 2h every time respectively, merges extracting solution, filtration；Filtrate is dense
The concentrate that relative density is 1.13~1.16 is shortened into, by large pore resin absorption column, using alcohol water gradient elution, water elution 3
A column volume, 10% and 30% ethyl alcohol respectively elute 3 column volumes, 70% column volume of ethanol elution 1；By eluent concentration, do
Total flavone extract of maniod eibish is obtained after dry, crushing.
Preferably, a kind of preparation method of privates washing lotion, includes the following steps：
(1) by section actinolitum brevifibrum, ginger, dark plum, Herba Andrographitis, wild chrysanthemum, the root bark of Chinese wolf-berry, hairyvein agrimony, Cortex Phellodendri, cordate houttuynia, kuh-seng
Mixing is crushed respectively with dandelion, the ethanol solutions of the 5 times of amounts 90% stirring and leaching 1h at 80 DEG C is added, by leaching liquor centrifugation point
From centrifuge speed 5000rpm obtains Chinese medicine extract；
(2) purslane ethanol extract and total flavone extract of maniod eibish are separately added into Chinese medicine extract, fully
Stir evenly the privates washing lotion prepared to get the present invention.
Each main composition mechanism of action of the present invention is as follows：
Actinolitum brevifibrum is the actinolitite that metamorphism is formed, mostly talc-schist.It is salty, tepor.Actinolitum brevifibrum plays cloudy supporing yang, temperature
Warm uterus；For cold uterus, fail to be impregnated for a long time, white excessive, the dripping diseases such as more than of leukorrhea.It is warming that external application can protect palace, improves leukorrhea etc.
Symptom.
The medicinal function of purslane is clearing heat and detoxicating, cooling blood and hemostasis, and purslane ethanol extract is to Escherichia coli, deformed rod
Bacterium, shigella dysenteriae, typhoid fever, paratyphosum Bacterium have the inhibiting effect of height to staphylococcus aureus, fungi Du big belly budlet such as difficult to understand
Born of the same parents' tinea bacterium, tubercle bacillus also have different degrees of inhibiting effect.
Flos abelmoschi manihot total flavones have apparent anti-inflammatory, antibacterial, the pharmacological actions such as analgesia.Clinically have with sunset abelmoschus flower list
Huang Kui capsule made of taste medicine has anti-inflammatory, diuresis, promoting blood circulation, dredging collateral effect, can significantly reduce Urine proteins, blood fat and blood creatinine,
Mitigate tubule-interstitial damage, improves Abelmoschus manihot, promote the transhipment and elimination of CIC (CIC ELISA), adjust
Ganglion cell's immune function mitigates the mediated injury of kidney of CIC and nephritis disease.
Ginger has the effects that quickening human metabolism, degrading the channel, scientific research find that ginger can play certain antibacterials
The effect of element, it is especially more preferable to salmonella effect.Ginger extract, which has to significantly inhibit dermatophyte and kill vagina, to drip
The effect of worm.
There is dark plum resisting pathogenic microbes effect, the effect to smooth muscle, dark plum can make the more parotid glands of salivary gland secretion
Hormone, parotin play the role of making blood vessel and body tissue's rejuvenation；Dark plum energy skin moistening and itch stopping, antiallergy, to blood-deficiency and wind-dry
Caused pruitus, urticaria, stubborn dermatitis etc. have good itching-relieving action.Dark plum washout, treatment colpomycosis are significant in efficacy.
The present invention has following advantageous effect：
Privates washing lotion prepared by the present invention is formed by forging actinolitum brevifibrum and plurality of Chinese extract for main component, nontoxic nothing
Evil, without side-effects, faint scent is pleasant, can pre- antimagnetic skin, foster skin, Staphylococcus aureus hemolytic coccus, pneumococcus, big can be inhibited
The bacteriums such as enterobacteria, shigella dysenteriae, Pseudomonas aeruginosa, typhoid bacillus, to Trichomonas vaginalis, pinworm plays the role of obviously inhibiting to kill,
Disease is prevented, washing lotion is used for a long time and plays the effect for preventing disease and health care simultaneously.
Specific implementation mode
In order to make the technical means, the creative features, the aims and the efficiencies achieved by the present invention be easy to understand, tie below
Specific embodiment is closed, the present invention is further explained.
Embodiment 1
A kind of privates washing lotion, is made of the raw material of following parts by weight：Forge 8 parts of actinolitum brevifibrum, purslane ethanol extract 5
Part, 4 parts of total flavone extract of maniod eibish, 1 part of ginger, 0.5 part of dark plum, 0.1 part of Herba Andrographitis, 0.2 part of wild chrysanthemum, the root bark of Chinese wolf-berry
0.1 part, 0.2 part of hairyvein agrimony, 0.2 part of Cortex Phellodendri, 0.2 part of cordate houttuynia, 0.1 part of kuh-seng, 0.2 part of dandelion.
The preparation method of the purslane ethanol extract is：Take it is dry spend more bacopa monnieri herb, 10 times of amounts are added
Refluxing extraction 2 times at 75 DEG C of 75~80% ethanol solution, each 1.5h merge extracting solution, are condensed into thick paste, and freezing is dry
It is dry, obtain purslane ethanol extract.
The preparation method of the total flavone extract of maniod eibish is：It takes sunset abelmoschus flower to clean up, 5~10 times of amounts is added
80% ethanol solution, heating extraction 2~3 times, extracts 2h every time respectively, merges extracting solution, filtration；Filtrate is condensed into relatively
The concentrate that density is 1.13~1.16, by large pore resin absorption column, using alcohol water gradient elution, 3 column volumes of water elution,
10% and 30% ethyl alcohol respectively elutes 3 column volumes, 70% column volume of ethanol elution 1；After eluent concentration, dry, crushing
Obtain total flavone extract of maniod eibish.
A kind of preparation method of privates washing lotion, includes the following steps：
(1) by section actinolitum brevifibrum, ginger, dark plum, Herba Andrographitis, wild chrysanthemum, the root bark of Chinese wolf-berry, hairyvein agrimony, Cortex Phellodendri, cordate houttuynia, kuh-seng
Mixing is crushed respectively with dandelion, the ethanol solutions of the 5 times of amounts 90% stirring and leaching 1h at 80 DEG C is added, by leaching liquor centrifugation point
From centrifuge speed 5000rpm obtains Chinese medicine extract；
(2) purslane ethanol extract and total flavone extract of maniod eibish are separately added into Chinese medicine extract, fully
Stir evenly the privates washing lotion prepared to get the present invention.
Embodiment 2
A kind of privates washing lotion, is made of the raw material of following parts by weight：Forge 10 parts of actinolitum brevifibrum, purslane ethanol extract 6
Part, 5 parts of total flavone extract of maniod eibish, 2 parts of ginger, 0.6 part of dark plum, 1.2 parts of Herba Andrographitis, 0.4 part of wild chrysanthemum, the root bark of Chinese wolf-berry
0.3 part, 1 part of hairyvein agrimony, 1 part of Cortex Phellodendri, 1 part of cordate houttuynia, 0.6 part of kuh-seng, 1 part of dandelion.
Embodiment 3
A kind of privates washing lotion, is made of the raw material of following parts by weight：Forge 11 parts of actinolitum brevifibrum, purslane ethanol extract 7
Part, 6 parts of total flavone extract of maniod eibish, 2.5 parts of ginger, 0.7 part of dark plum, 1.6 parts of Herba Andrographitis, 0.6 part of wild chrysanthemum, the root bark of Chinese wolf-berry
0.5 part, 1.3 parts of hairyvein agrimony, 1.3 parts of Cortex Phellodendri, 1.5 parts of cordate houttuynia, 0.9 part of kuh-seng, 1.5 parts of dandelion.
Embodiment 4
A kind of privates washing lotion, is made of the raw material of following parts by weight：Forge 12 parts of actinolitum brevifibrum, purslane ethanol extract 8
Part, 7 parts of total flavone extract of maniod eibish, 3 parts of ginger, 0.8 part of dark plum, 2 parts of Herba Andrographitis, 0.8 part of wild chrysanthemum, the root bark of Chinese wolf-berry 0.6
Part, 1.6 parts of hairyvein agrimony, 1.6 parts of Cortex Phellodendri, 2 parts of cordate houttuynia, 1.2 parts of kuh-seng, 2 parts of dandelion.
Embodiment 5
A kind of privates washing lotion, is made of the raw material of following parts by weight：Forge 13 parts of actinolitum brevifibrum, purslane ethanol extract 10
Part, 8 parts of total flavone extract of maniod eibish, 4 parts of ginger, 1 part of dark plum, 2.4 parts of Herba Andrographitis, 1 part of wild chrysanthemum, 1 part of the root bark of Chinese wolf-berry, celestial being
2 parts of crane grass, 2 parts of Cortex Phellodendri, 3 parts of cordate houttuynia, 1.8 parts of kuh-seng, 3 parts of dandelion.
Comparative example 1
Difference lies in forge actinolitum brevifibrum in the washing lotion of preparation without addition with embodiment 1.
Comparative example 2
Difference lies in without addition purslane ethanol extract in the washing lotion of preparation with embodiment 1.
Comparative example 3
Difference lies in without addition total flavone extract of maniod eibish in the washing lotion of preparation with embodiment 1.
Efficacy validation
240 female patients with symptoms such as pruritus vulvues of selection are tested, and clinical manifestation is itch, with vulva
Humidity, secretion increases, peculiar smell or sees spiritlessness and weakness, soreness and weakness of waist and knees, aversion to cold and cold limbs.Be randomly divided into 8 groups, every group 30, to
The washing lotion that upper patient is prepared using 1-5 of the embodiment of the present invention and comparative example 1-3, by recipe quantity as one, one dose per day, daily
Smoked to wash 2 times, each 1 time sooner or later, 15 days as a treatment course count effect after three courses for the treatment of.Experimental result is as shown in table 1 below：
Efficacy assessment standard：
It is effective：Symptomatology is eliminated or cardinal symptom is restored, and can participate in normal work and labour；
Effectively：Cardinal symptom substantially eliminates, and sings and symptoms are improved in varying degrees；
In vain：It compares with before treatment, various aspects are without improvement.
The using effect of 1 each washing lotion of table
As seen from the above table, actinolitum brevifibrum is forged it is found that being added in the washing lotion of preparation by the comparison of embodiment 1 and comparative example 1,
The efficient raising 23.4% that the symptoms such as the pruritus vulvue of patient can be improved；Pass through the comparison of embodiment 1 and comparative example 2
It is found that adding purslane ethanol extract in the washing lotion of preparation, can have what the symptoms such as the pruritus vulvue of patient were improved
Efficiency improves 20.0%；By the comparison of embodiment 1 and comparative example 3 it is found that add sunset abelmoschus flower in the washing lotion of preparation always yellow
Ketone extract, the efficient raising 30.0% that the symptoms such as the pruritus vulvue of patient can be improved.
In summary, it is added in privates washing lotion prepared by the present invention and forges actinolitum brevifibrum, purslane ethanol extract and yellow another name for Sichuan Province
The effect of sunflower extractive of general flavone can significantly improve the symptoms such as pruritus vulvue, effectively improve washing lotion.
Several embodiments of the invention above described embodiment only expresses, the description thereof is more specific and detailed, but simultaneously
Cannot the limitation to the scope of the claims of the present invention therefore be interpreted as.It should be pointed out that for those of ordinary skill in the art
For, without departing from the inventive concept of the premise, various modifications and improvements can be made, these belong to the guarantor of the present invention
Protect range.
Claims (6)
1. a kind of privates washing lotion, which is characterized in that be made of the raw material of following parts by weight：Forge 8~13 parts of actinolitum brevifibrum, purslane
5~10 parts of ethanol extract, 4~8 parts of total flavone extract of maniod eibish, 1~4 part of ginger, 0.5~1 part of dark plum, Herba Andrographitis
0.1~2.4 part, 0.2~1 part of wild chrysanthemum, 0.1~1 part of the root bark of Chinese wolf-berry, 0.2~2 part of hairyvein agrimony, 0.2~2 part of Cortex Phellodendri, cordate houttuynia
0.2~3 part, 0.1~1.8 part of kuh-seng, 0.2~3 part of dandelion.
2. a kind of privates washing lotion according to claim 1, which is characterized in that be made of the raw material of following parts by weight：It forges
10~12 parts of actinolitum brevifibrum, 6~8 parts of purslane ethanol extract, 5~7 parts of total flavone extract of maniod eibish, 2~3 parts of ginger,
0.6~0.8 part of dark plum, 1.2~2 parts of Herba Andrographitis, 0.4~0.8 part of wild chrysanthemum, 0.3~0.6 part of the root bark of Chinese wolf-berry, hairyvein agrimony 1~1.6
Part, 1~1.6 part of Cortex Phellodendri, 1~2 part of cordate houttuynia, 0.6~1.2 part of kuh-seng, 1~2 part of dandelion.
3. a kind of privates washing lotion according to claim 2, which is characterized in that be made of the raw material of following parts by weight：It forges
11 parts of actinolitum brevifibrum, 6 parts of total flavone extract of maniod eibish, 2.5 parts of ginger, 0.7 part of dark plum, is worn 7 parts of purslane ethanol extract
1.6 parts of heart lotus, 0.6 part of wild chrysanthemum, 0.5 part of the root bark of Chinese wolf-berry, 1.3 parts of hairyvein agrimony, 1.3 parts of Cortex Phellodendri, 1.5 parts of cordate houttuynia, kuh-seng 0.9
Part, 1.5 parts of dandelion.
4. according to a kind of privates washing lotion of claims 1 to 3 any one of them, which is characterized in that the purslane ethyl alcohol extraction
The preparation method of object is：Take it is dry spend more bacopa monnieri herb, the ethanol solution of 10 times of amounts 75~80% is added at 75 DEG C
Refluxing extraction 2 times, each 1.5h merges extracting solution, is condensed into thick paste, is freeze-dried, obtains purslane ethanol extract.
5. according to a kind of privates washing lotion of claims 1 to 3 any one of them, which is characterized in that the Flos abelmoschi manihot total flavones
The preparation method of extract is：It takes sunset abelmoschus flower to clean up, the ethanol solution of 5~10 times of amounts 80% is added, heating respectively carries
It takes 2~3 times, extracts 2h every time, merge extracting solution, filtration；Filtrate is condensed into the concentrate that relative density is 1.13~1.16,
By large pore resin absorption column, using alcohol water gradient elution, 3 column volumes of water elution, 10% and 30% ethyl alcohol respectively elutes 3 columns
Volume, 70% column volume of ethanol elution 1；Total flavone extract of maniod eibish will be obtained after eluent concentration, dry, crushing.
6. a kind of prepare such as a kind of method of privates washing lotion of Claims 1 to 5 any one of them, which is characterized in that including with
Lower step：
(1) by section actinolitum brevifibrum, ginger, dark plum, Herba Andrographitis, wild chrysanthemum, the root bark of Chinese wolf-berry, hairyvein agrimony, Cortex Phellodendri, cordate houttuynia, kuh-seng and Pu
Public scruple does not crush mixing, and the ethanol solutions of the 5 times of amounts 90% stirring and leaching 1h at 80 DEG C is added, leaching liquor is centrifuged,
Centrifuge speed is 5000rpm, obtains Chinese medicine extract；
(2) it is separately added into purslane ethanol extract and total flavone extract of maniod eibish in Chinese medicine extract, is sufficiently stirred
The privates washing lotion uniformly prepared to get the present invention.
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| CN201810543281.3A CN108379546A (en) | 2018-05-29 | 2018-05-29 | A kind of privates washing lotion and preparation method thereof |
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS58213719A (en) * | 1982-06-02 | 1983-12-12 | Yasuo Araki | Drug activator |
| CN103405586A (en) * | 2013-08-03 | 2013-11-27 | 武汉诺贝药业有限公司 | Lemna minor total flavonoid extract and preparation method thereof |
| CN104173865A (en) * | 2014-07-15 | 2014-12-03 | 郭永德 | Chinese herbal medicine insecticidal sterilization nourishing lotion for diminishing inflammation, relieving itching and protecting skin |
| EP2937093A1 (en) * | 2008-07-22 | 2015-10-28 | Izun Pharmaceuticals Corporation | Topical anti-inflammatory combination |
-
2018
- 2018-05-29 CN CN201810543281.3A patent/CN108379546A/en not_active Withdrawn
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS58213719A (en) * | 1982-06-02 | 1983-12-12 | Yasuo Araki | Drug activator |
| EP2937093A1 (en) * | 2008-07-22 | 2015-10-28 | Izun Pharmaceuticals Corporation | Topical anti-inflammatory combination |
| CN103405586A (en) * | 2013-08-03 | 2013-11-27 | 武汉诺贝药业有限公司 | Lemna minor total flavonoid extract and preparation method thereof |
| CN104173865A (en) * | 2014-07-15 | 2014-12-03 | 郭永德 | Chinese herbal medicine insecticidal sterilization nourishing lotion for diminishing inflammation, relieving itching and protecting skin |
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Application publication date: 20180810 |