CN108210714A - It is a kind of for pharmaceutical composition of eye surface diseases and preparation method thereof and purposes - Google Patents
It is a kind of for pharmaceutical composition of eye surface diseases and preparation method thereof and purposes Download PDFInfo
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/428—Trichosanthes
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- A61K36/56—Loganiaceae (Logania family), e.g. trumpetflower or pinkroot
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/80—Scrophulariaceae (Figwort family)
- A61K36/804—Rehmannia
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/80—Scrophulariaceae (Figwort family)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8968—Ophiopogon (Lilyturf)
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- A61K9/00—Medicinal preparations characterised by special physical form
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- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/35—Extraction with lipophilic solvents, e.g. Hexane or petrol ether
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Abstract
The invention discloses a kind of for pharmaceutical composition of eye surface diseases and preparation method thereof and purposes, which counts in parts by weight includes：3 ~ 5 parts of honeysuckle, 3 ~ 5 parts of Fructus Forsythiae, 3 ~ 5 parts of chrysanthemum, 28 ~ 32 parts of radix scrophulariae, 2 ~ 4 parts of Radix Ophiopogonis, 3 ~ 5 parts of rhizoma atractylodis, 2 ~ 4 parts of Cortex Phellodendri, 2 ~ 4 parts of root of Chinese trichosanthes, 5 ~ 8 parts of Radix Rehmanniae, illiteracy spend 3 ~ 5 parts.It is highly preferred that the composition includes by weight：Honeysuckle 2kg, Fructus Forsythiae 2kg, chrysanthemum 2kg, radix scrophulariae 15kg, Radix Ophiopogonis 1.5kg, rhizoma atractylodis 2kg, Cortex Phellodendri 1.5kg, root of Chinese trichosanthes 1.5kg, Radix Rehmanniae 3kg cover flower 2kg.The present invention also provides the preparation methods and purposes of the pharmaceutical composition.Pharmaceutical composition provided by the present invention for eye surface diseases and preparation method thereof and purposes, have the characteristics that reasonable recipe, dosage it is few, it is significant in efficacy, have no toxic side effect, be rapidly reached effect.
Description
Technical field
The present invention relates to a kind of herbal fumigation preparation compositions and preparation method thereof and purposes, and in particular, to Yi Zhongyong
In pharmaceutical composition of eye surface diseases and preparation method thereof and purposes.
Background technology
Herbal fumigation therapy is also known as Chinese medicine steaming therapy, Chinese-Medicine-Steam balneation, the saturating therapy of medicine, hot mist therapy etc..At some
Minority area is referred to as " drying refined ".Herbal fumigation is chemistry, the physical comprehensive treatment using medicine of a warm nature steam as the treatment factor.
This method earliest for it is clinical from the pre-Qin days with regard on the books, later age is no lack of its art.To the Qing Dynasty, herbal fumigation tends to be ripe.With
The progress of section's art, herbal fumigation is either theoretical or practice has corresponding development, now gradually general to use ENT dept.（Ear
Section, ophthalmology etc.）, all various aspects such as rehabilitation physical therapy.Traditional Chinese medicine fumigation and steaming therapy is the important component of external treatment with Chinese medicine, Qing Dynasty Wu Shi
Machine《Li Yue Pianwen, Rhymed Discourse for Topical Remedies》It says：" the i.e. interior reason controlled of the reason controlled outside, the medicine controlled outside, that is, the interior medicine controlled, the different person of institute, method ear ".Traditional Chinese medicine fumigating
The method of washing is a kind of common outer treating method in Chinese traditional treatment, is to select suitable drug according to specific disease symptoms, by these
Drug is fried into decoction to fumigate a kind of therapy of affected part, and Chinese herbal fumigation and washing not only has the pharmacological action of Chinese medicine, while also has
There is thermogenetic effect, drug absorption can be promoted, by accelerating blood circulation, local disease is made to make timely rehabilitation, this is often used in ophthalmology
Kind of smoked hair washing treatment inflamed eyes, the puckery pain of photophobia, etc. ophthalmology illness.The outer fumigation treatment dry eyes of traditional Chinese medicine be using Chinese herbs decoction its
The therapy of eye is smoked on heat steaming up, there is the effect of physics applying hot soaks and drug to guide drugs to illness station the double action for the treatment of,
Distinctive feature is to supplement the deficiency of medicine for oral administration.Warm stimulation can increase eyelid temperature, be allowed to the fusing point for being higher than Meibomian gland lipid
In favor of the flowing of lipid；It can make eyelid, conjunctiva telangiectasis, promote eyelid, conjunctiva blood and lymph circulation, promote
Into the benign or normal secretions of Meibomian gland, Meibomian gland opening clear is conducive to Medicated Permeation, absorption and propagation.Herbal fumigation removes
Warm stimulation, also wettable eyelid, conjunctiva, cornea solve eyelid, conjunctiva, bitot's patches discomfort and feel, reach treatment dry eyes
Purpose.
Eye surface diseases（Ocular surface disease, OSD）Concept, refer to damage angle conjunctival surface normal configuration
With the disease of function.Since ocular is a global concept, thus functionally need eye surface diseases and tear disease syndrome,
It is summarised as ocular tear disease（ocular surface & tear disease）.Dry eyes：Angle xerosis of conjunctiva
（keratoconjunctivitis sicca）Also known as dry eyes（dry eye）, it is a kind of common eye surface diseases, refers to any reason
Caused tear matter or amount is abnormal or the extremely caused tear film stability of dynamics declines, and with ophthalmic uncomfortable and（Or）Eye
The general name of a variety of diseases that table organization's lesion is characterized.Dry eyes are divided into following four type according to adacrya ingredient：Water sample
Liquid shortage property, mucoprotein shortage property, lipid shortage property and tear dynamics（Distribution）Abnormality.Traditional Chinese medicine thinks that ancient times cure
Family's xerophthalmia is referred to as " white puckery ".Ming Dynasty's medical book《Precious Book of Ophthalmology》Described in：" pneumonedema is not red, frankness must not, husky puckery dusk is dim, name day
It is white puckery '." this disease is mainly that the deficiency of Yin is scorching, cause oligodacrya that cannot moisten caused by eyes.The traditional Chinese medical science thinks body fluid pair
Each histoorgan of human body supports effect, and tears belong to one kind in human body body fluid, has the function of that moist mesh pearl is once internal
The deficiency of Yin is scorching, then can damage body fluid.Lead to tears hyposecretion, eyes, which just lose, to be sent out in supporting as xerophthalmia.The elderly's age
Increase, internal body fluid relative deficiency, it is easier to cease xerophthalmia.In throughout the year, spring, autumn, three season of the winter a little xerophthalmia of relatively dry
Incidence it is also relatively high.
The drug of western medical treatment eye surface diseases mainly has various antibiotic, artificial tears etc. at present.These drugs for
Control inflammation of eye section usually all relatively effective, but its there is also following shortcomings.(1) choice of drug limitation：Child patient,
The heart, lung, Liver and kidney function patients with abnormal, acute complications（Such as ketoacidosis）Or serious chronic complicating diseases patient has not
Same contraindication, therefore the validity of drug must should be just considered during medication, avoid drug that may be produced in itself to patient again
Raw toxic side effect.（2）Antibiotic Resistance secondary failure easily occurs：With the extension of the course of disease, many antibiotic are such as
Ofloxacin eye drops etc. can generate drug resistance, and therapeutic effect can continuously decrease, oneself will necessarily cause serious concurrent long for a long time
Disease.（3）Most of artificial tears can only improve xerophthalmia, it is impossible to treat, and prolonged application curative effect is also bad.
Invention content
The object of the present invention is to provide a kind of for pharmaceutical composition of herbal fumigation preparation and preparation method thereof and purposes,
Existing issue can be solved, not only can effectively control inflammation of eye section, but also ocular inflammation and treatment can be effectively improved to improve xerophthalmia, regard
The diseases such as fatigue.
In order to achieve the above object, the present invention provides a kind of pharmaceutical composition, wherein, the composition is counted in parts by weight
Comprising：3 ~ 5 parts of honeysuckle, 3 ~ 5 parts of Fructus Forsythiae, 3 ~ 5 parts of chrysanthemum, 28 ~ 32 parts of radix scrophulariae, 2 ~ 4 parts of Radix Ophiopogonis, 3 ~ 5 parts of rhizoma atractylodis, Cortex Phellodendri 2 ~ 4
Part, 2 ~ 4 parts of root of Chinese trichosanthes, 5 ~ 8 parts of Radix Rehmanniae covers and spends 3 ~ 5 parts.
Above-mentioned pharmaceutical composition, wherein, preferably meter includes the composition in parts by weight：4 parts of honeysuckle, even
Stick up 4 parts, 4 parts of chrysanthemum, 30 parts of radix scrophulariae, 3 parts of Radix Ophiopogonis, 4 parts of rhizoma atractylodis, 3 parts of Cortex Phellodendri, 3 parts of root of Chinese trichosanthes, 6 parts of Radix Rehmanniae, illiteracy spends 4 parts.
Above-mentioned pharmaceutical composition, wherein, the composition more preferably includes by weight：Honeysuckle 2kg, Fructus Forsythiae
2kg, chrysanthemum 2kg, radix scrophulariae 15kg, Radix Ophiopogonis 1.5kg, rhizoma atractylodis 2kg, Cortex Phellodendri 1.5kg, root of Chinese trichosanthes 1.5kg, Radix Rehmanniae 3kg cover flower 2kg.
The present invention also provides the preparation method of above-mentioned pharmaceutical composition, wherein, the method is：It weighs in proportion
Each raw material, grinding is broken respectively, and the process by decocting water, concentration, extraction, products therefrom are evaporated into graininess, are divided into successively
Parcel is packed.
The preparation method of above-mentioned pharmaceutical composition, wherein, it is 20 ~ 40 that broken particle size range is ground in the method
Mesh after drug grinding is broken, soaks 60 ~ 90min, and then heating decocts 2 ~ 3 times, and 50 ~ 80min, will decoct every time every time
Gained filtrate is concentrated after merging, and is obtained drug extract, is then extracted by lipophilic organic solvent, then will recycling
The extraction product of gained is evaporated after solvent, is obtained solid particle, is divided into parcel and is packed.The solvent of extraction is preferably chloroform.
The preparation method of above-mentioned pharmaceutical composition, wherein, the parcel that is divided into the method is packed, per parcel
In solid particle weight be 10 ~ 20g.Preferably 15g.
Present invention provides the purposes of pharmaceutical composition prepared by above-mentioned method, wherein, the pharmaceutical composition
It is used to prepare the preparation ruled by law by herbal fumigation and treat eye surface diseases.
The purposes of above-mentioned pharmaceutical composition, wherein, after the pharmaceutical composition is packaged into parcel, it is put into when in use
Herbal fumigation machine fumigates affected part for patient.Chinese medicine package is placed on Chinese medicine to boil in steaming device, direct decocting herb, generates medicine steam,
For fumigating, a packet pharmaceutical composition can be used continuously 2~3 times or so, every time 15 ~ 25min.The herbal fumigation machine is preferred
For commercially available Miniature Chinese medicine gassing machine, it is convenient for partial fumigating.
Pharmaceutical composition provided by the present invention for eye surface diseases and preparation method thereof has the following advantages with purposes：
The pharmaceutical composition provided by the present invention for being used to treat eye surface diseases, using unique therapy of traditional Chinese medicine preparation in
Medicine be put into gassing machine carry out eye disease treatment, than directly fumigating better efficacy with active compound, it is easier to through skin histology,
Eye-retinal barrier, better efficacy can reach through the traditional Chinese medical science and the various eye surface diseases of traditional Chinese medicine composition for treating, xerophthalmia, regard
The effect of fatigue etc., have the characteristics that reasonable recipe, dosage it is few, it is significant in efficacy, have no toxic side effect, be rapidly reached effect.
Specific embodiment
The specific embodiment of the present invention is further described below.
Pharmaceutical composition provided by the invention is counted in parts by weight to be included：3 ~ 5 parts of honeysuckle, 3 ~ 5 parts of Fructus Forsythiae, chrysanthemum 3 ~ 5
Part, 28 ~ 32 parts of radix scrophulariae, 2 ~ 4 parts of Radix Ophiopogonis, 3 ~ 5 parts of rhizoma atractylodis, 2 ~ 4 parts of Cortex Phellodendri, 2 ~ 4 parts of root of Chinese trichosanthes, 5 ~ 8 parts of Radix Rehmanniae, illiteracy spend 3 ~ 5 parts.
Preferably, the composition is counted include in parts by weight：4 parts of honeysuckle, 4 parts of Fructus Forsythiae, 4 parts of chrysanthemum, 30 parts of radix scrophulariae, wheat
3 parts of winter, 4 parts of rhizoma atractylodis, 3 parts of Cortex Phellodendri, 3 parts of root of Chinese trichosanthes, 6 parts of Radix Rehmanniae, illiteracy spend 4 parts.
It is highly preferred that the composition includes by weight：Honeysuckle 2kg, Fructus Forsythiae 2kg, chrysanthemum 2kg, radix scrophulariae 15kg, Radix Ophiopogonis
1.5kg, rhizoma atractylodis 2kg, Cortex Phellodendri 1.5kg, root of Chinese trichosanthes 1.5kg, Radix Rehmanniae 3kg cover flower 2kg.
The present invention also provides the preparation method of the pharmaceutical composition, this method is：Each raw material is weighed in proportion, is ground respectively
Broken, and the process by decocting water, concentration, extraction successively is galled, products therefrom is evaporated into graininess, is divided into parcel and packed.
Preferably, broken particle size range is ground in this method as 20 ~ 40 mesh, after drug grinding is broken, soak 60 ~
90min, then heating decoct 2 ~ 3 times, and 50 ~ 80min, each decoct after gained filtrate merges is concentrated, obtains medicine every time
Then object medicinal extract is extracted by lipophilic organic solvent, the solvent of extraction is preferably chloroform.Again by institute after recycling design
Extraction product be evaporated, obtain solid particle, be divided into parcel and packed, per the solid particle weight in parcel for 10 ~
20g.Preferably 15g.
Present invention provides the purposes of pharmaceutical composition prepared by this method, which is used to prepare in
Medicine-smoking steams the preparation that eye surface diseases are treated in ruling by law.After pharmaceutical composition is packaged into parcel, it is put into herbal fumigation machine when in use, to suffer from
Person fumigates affected part.Chinese medicine package is placed on Chinese medicine to boil in steaming device, direct decocting herb, generates medicine steam, for fumigating, a packet medicine
Compositions can be used continuously 2~3 times or so, every time 15 ~ 25min.The herbal fumigation machine is preferably that commercially available Miniature Chinese medicine is smoked
Steaming machine, is convenient for partial fumigating.
With reference to embodiment to pharmaceutical composition provided by the present invention for eye surface diseases and preparation method thereof with
Way is further described.
Embodiment 1 ~ 4
Material composition proportioning shown in each embodiment difference according to the form below 1 prepares pharmaceutical composition.Each raw material corresponds with accordingly
National standard.
The list of ingredients (by weight) of 1. pharmaceutical composition of table.
| Raw material | Embodiment 1 | Embodiment 2 | Embodiment 3 | Embodiment 4 |
| Honeysuckle | 2kg | 1kg | 1.5kg | 2.5kg |
| Fructus Forsythiae | 2kg | 1kg | 1.5kg | 2.5kg |
| Chrysanthemum | 2kg | 1kg | 1.5kg | 2.5kg |
| Radix scrophulariae | 15kg | 7.5kg | 14kg | 16kg |
| Radix Ophiopogonis | 1.5kg | 0.75kg | 1kg | 2kg |
| Rhizoma atractylodis | 2kg | 1kg | 1.5kg | 2.5kg |
| Cortex Phellodendri | 1.5kg | 0.75kg | 1kg | 2kg |
| Root of Chinese trichosanthes | 1.5kg | 0.75kg | 1kg | 2kg |
| Radix Rehmanniae | 3kg | 1.5kg | 2.5kg | 4kg |
| Cover flower | 2kg | 1kg | 1.5kg | 2.5kg |
The present invention also provides the preparation method of the pharmaceutical composition of each embodiment and the drugs of each embodiment prepared
The purposes of composition.
Weigh each raw material in pharmaceutical composition in proportion, then smash respectively, decoct water, concentration, extraction, active ingredient into
Graininess, packing often wrap 15 grams, are packed like tea bag sample, are put into herbal fumigation machine, are fumigated to patient.
Patient is chosen by random device, is divided into experimental group, control group, every group 40.Experimental group uses the embodiment of the present invention 1
Prepared pharmaceutical composition carries out herbal fumigation, 3 times a day, each 20min.Control group does not use drug provided by the invention
Composition.It is 4 weeks to compare administration time.The symptom of eye surface diseases that all patients of experimental group can be obtained by observing is mitigated
And alleviation, 55% patient symptom disappear substantially.
Pharmaceutical composition provided by the present invention for eye surface diseases and preparation method thereof and purposes, through Chinese medical discrimination, lung
With regulating fluid apssage, the function of normal aqueous metabolism is maintained.Lack of lung-YIN can then lead to the dysfunction of its regulating fluid apssage, eyes
Lack body fluid, send out as xerophthalmia.The treatment of this type xerophthalmia should using yin-nourishing, moistening lung, heat-clearing as main diabetes be that the deficiency of Yin is
Originally, the scorching impairment of both QI and YIN for caused by mark.Therefore the principle of generally use is yin-nourishing tonifying Qi in the treatment, nourishes negative and positive, promoting blood circulation
Stagnation resolvation.Provided by the present invention for Traditional Chinese medicine compositions such as treatment eye surface diseases, xerophthalmia, visual fatigues, exactly in the theory
Guidance under, for the etiology and pathogenesis of disease, using the complementary compatibility principle of drug, purposefully by all medicines by monarch, minister,
The institutional framework reasonable compatibility help, made, the drug and its compatibility and the interpretation of the cause, onset and process of an illness of disease in the side of making are intricately woven together, after making compatibility of drugs
Aggreggate utility and the vertical therapy high unity of institute.
The pharmaceutical composition is included by the range that herbal fumigation method is treated：One, it treats in eye illness and leads to, red train of thought mesh is shy
Bright more tears, hidden puckery difficulty is opened or even the cloudiness person that climbs eyeball；Two, liver and gall heated attacks dotting punch mesh, the red red swelling of eyelid, pain with tenderness, when
There is routed purulence, hot tears such as soup or see that ala hides eyeball；3rd, alleviate visual fatigue, xerophthalmia eliminates the puffiness of the eyes, prevents eye needle, graupel grain
It swells.
Although present disclosure is discussed in detail by above preferred embodiment, but it should be appreciated that above-mentioned
Description is not considered as limitation of the present invention.After those skilled in the art have read the above, for the present invention's
A variety of modifications and substitutions all will be apparent.Therefore, protection scope of the present invention should be limited to the appended claims.
Claims (8)
1. a kind of pharmaceutical composition, which is characterized in that the composition is counted include in parts by weight：
3 ~ 5 parts of honeysuckle, 3 ~ 5 parts of Fructus Forsythiae, 3 ~ 5 parts of chrysanthemum, 28 ~ 32 parts of radix scrophulariae, 2 ~ 4 parts of Radix Ophiopogonis, 3 ~ 5 parts of rhizoma atractylodis, Cortex Phellodendri 2 ~ 4
Part, 2 ~ 4 parts of root of Chinese trichosanthes, 5 ~ 8 parts of Radix Rehmanniae covers and spends 3 ~ 5 parts.
2. pharmaceutical composition as described in claim 1, which is characterized in that the composition is counted in parts by weight to be included：
4 parts of honeysuckle, 4 parts of Fructus Forsythiae, 4 parts of chrysanthemum, 30 parts of radix scrophulariae, 3 parts of Radix Ophiopogonis, 4 parts of rhizoma atractylodis, 3 parts of Cortex Phellodendri, 3 parts of root of Chinese trichosanthes, Radix Rehmanniae
6 parts, illiteracy spends 4 parts.
3. pharmaceutical composition as claimed in claim 2, which is characterized in that the composition includes by weight：
Honeysuckle 2kg, Fructus Forsythiae 2kg, chrysanthemum 2kg, radix scrophulariae 15kg, Radix Ophiopogonis 1.5kg, rhizoma atractylodis 2kg, Cortex Phellodendri 1.5kg, root of Chinese trichosanthes
1.5kg, Radix Rehmanniae 3kg cover flower 2kg.
4. the preparation method of a kind of pharmaceutical composition as described in any one in claim 1 ~ 3, which is characterized in that described
Method is：Each raw material is weighed in proportion, and grinding is broken respectively, and the process by decocting water, concentration, extraction successively, products therefrom
Graininess is evaporated into, is divided into parcel and is packed.
5. the preparation method of pharmaceutical composition as claimed in claim 4, which is characterized in that grind what is crushed in the method
Particle size range is 20 ~ 40 mesh, after drug grinding is broken, soaks 60 ~ 90min, and then heating decocts 2 ~ 3 times, every time 50 ~
Each decoct after gained filtrate merges is concentrated, obtains drug extract, then pass through lipophilic organic solvent by 80min
It is extracted, then the extraction product of gained after recycling design is evaporated, obtained solid particle, be divided into parcel and packed.
6. the preparation method of pharmaceutical composition as claimed in claim 5, which is characterized in that be divided into parcel in the method
It is packed, the solid particle weight in every parcel is 10 ~ 20g.
A kind of 7. purposes of pharmaceutical composition prepared by method as claimed in claim 4, which is characterized in that the medicine group
It closes object and is used to prepare the preparation ruled by law by herbal fumigation and treat eye surface diseases.
8. the purposes of pharmaceutical composition as claimed in claim 7, which is characterized in that the pharmaceutical composition is packaged into parcel
Afterwards, it is put into herbal fumigation machine when in use, affected part is fumigated for patient.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810072965.XA CN108210714A (en) | 2018-01-25 | 2018-01-25 | It is a kind of for pharmaceutical composition of eye surface diseases and preparation method thereof and purposes |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201810072965.XA CN108210714A (en) | 2018-01-25 | 2018-01-25 | It is a kind of for pharmaceutical composition of eye surface diseases and preparation method thereof and purposes |
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| CN108210714A true CN108210714A (en) | 2018-06-29 |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109106830A (en) * | 2018-10-18 | 2019-01-01 | 王杰生 | A kind of composition and preparation method thereof and purposes |
| CN109758533A (en) * | 2019-03-18 | 2019-05-17 | 陈培培 | A kind of pharmaceutical composition for eyeshield and preparation method thereof and purposes |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102145126A (en) * | 2011-04-13 | 2011-08-10 | 张铭连 | Pharmaceutical composition for treating xerophthalmia |
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2018
- 2018-01-25 CN CN201810072965.XA patent/CN108210714A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102145126A (en) * | 2011-04-13 | 2011-08-10 | 张铭连 | Pharmaceutical composition for treating xerophthalmia |
Non-Patent Citations (1)
| Title |
|---|
| 魏春秀，等: "应重视外用熏洗剂对眼表疾病的治疗作用", 《中国中医眼科杂志》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109106830A (en) * | 2018-10-18 | 2019-01-01 | 王杰生 | A kind of composition and preparation method thereof and purposes |
| CN109758533A (en) * | 2019-03-18 | 2019-05-17 | 陈培培 | A kind of pharmaceutical composition for eyeshield and preparation method thereof and purposes |
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Application publication date: 20180629 |