CN109731088A - A kind of Traditional Chinese medicine composition for relieving asthenopia and its preparation method and application - Google Patents
A kind of Traditional Chinese medicine composition for relieving asthenopia and its preparation method and application Download PDFInfo
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Abstract
The invention discloses a kind of Traditional Chinese medicine composition for relieving asthenopia and its preparation method and application, are made of following raw materials according: radix angelicae sinensis, Rhizoma Chuanxiong, safflower, ramulus cinnamomi, wild chrysanthemum, cordate houttuynia, cassia seed, the seed of feather cockscomb, Prunella vulgaris, peppermint, cortex moutan, rhizoma anemarrhenae, fructus lycii, radix rehmanniae preparata, cortex cinnamomi, the root of Chinese clematis, Radix Salviae Miltiorrhizae, pueraria lobata, Radix Ophiopogonis, Fructus Liquidambaris, Sargent gloryvine, folium artemisiae argyi, fructus alpiniae oxyphyllae, rhizoma polygonati, Semen Cuscutae, corydalis tuber, the achene of Siberian cocklebur, the coptis, mulberry leaf, semen plantaginis and Radix Astragali.The relationship between " liver kidney and eye " and specific aim that the present invention passes through Chinese medicine state of internal organs theory improve the microcirculation of eye muscle, using heat-clearing improving eyesight, promoting blood circulation to remove blood stasis as therapy, deed prescription of starting with, to reach the therapeutic effect for alleviating visual fatigue；By the rational proportion of each Chinese medicine, synergistic effect, there is significant curative effect to visual fatigue is alleviated, and does not recur.
Description
Technical field
The present invention relates to technical field of traditional Chinese medicines, specifically a kind of Traditional Chinese medicine composition for relieving asthenopia and preparation method thereof
And application.
Background technique
The syndrome for the subjective symptom that asthenopia, which refers to, to be generated when being worked with eye, asthenopia is common one of current ophthalmology
Kind of disease, the symptom of patient is varied, and common are near work cannot be lasting, lose face out and eye socket around pain, view
Object is fuzzy, eyes are dry and astringent, shed tears, serious person's headache, nausea, dizziness, its not independent disease, due to various reasons
Caused one group of fatigue syndrome；Modern society's work rhythm is accelerated, and working time opposite lengthening, contact light source machine can increase,
So that eye fatigue is increasingly obvious, occurrence cause be also it is diversified, it is common to have: the reason of eyes itself, such as myopia, remote
Depending on ametropia, the adjusting factors such as, astigmatism, eye muscle factor, conjunctivitis, keratitis, wear glasses it is improper etc.；Systemic factor,
Such as neurasthenia, body overwork, hysteria or involutional women；Environmental factor, if illumination is insufficient or too strong, distribution of light sources is uneven
Even or glimpse, the target watched attentively is too small, meticulous or unstable etc..Under normal circumstances, intra tear will form people
One tunic is covered on the surface of cornea and conjunctiva, referred to as tear film；After people blinks every time, one layer of tear film, Ke Yibao can be formed
It is wet and comfortable to hold eyes, therefore is not likely to produce the symptoms such as the dry, fatigue of eye；If staring at a target time duration for a long time too
Long, blink reflection is fewer, cannot form tear film in time, will lead to eye surface drying, causes asthenopia, although current one
A little medicament for the eyes water energys relieve fatigue symptom, but can not eradicate asthenopia.
The drug for the treatment of asthenopia at present, in, western drug have, but clinical observation discovery effect is undesirable, such as big
Majority has been short-term booster action, cannot thoroughly be treated.
Summary of the invention
It is an object of the present invention to provide a kind of Chinese medicine compositions, under guidance of traditional Chinese medicine theory, pass through the reasonable of each Chinese medicine
Synergistic effect between proportion and effective component has specific therapeutic effect to asthenopia is alleviated.
In order to achieve the above objectives, The technical solution adopted by the invention is as follows:
A kind of Traditional Chinese medicine composition for relieving asthenopia is made of: radix angelicae sinensis the raw material of following parts by weight
10~30g, 10~20g of Rhizoma Chuanxiong, 10~30g of safflower, 20~40g of ramulus cinnamomi, 20~40g of wild chrysanthemum, cordate houttuynia 5~
15g, 15~35g of cassia seed, 10~20g of the seed of feather cockscomb, 15~35g of Prunella vulgaris, 10~20g of peppermint, 10~20g of cortex moutan, rhizoma anemarrhenae
10~30g, 10~20g of fructus lycii, 10~20g of radix rehmanniae preparata, 10~20g of cortex cinnamomi, 10~30g of the root of Chinese clematis, 10~30g of Radix Salviae Miltiorrhizae, pueraria lobata 20
~40g, 10~30g of Radix Ophiopogonis, 15~35g of Fructus Liquidambaris, 20~40g of Sargent gloryvine, 10~20g of folium artemisiae argyi, 10~30g of fructus alpiniae oxyphyllae, rhizoma polygonati 10
~20g, 10~30g of Semen Cuscutae, 15~35g of corydalis tuber, 10~30g of the achene of Siberian cocklebur, 5~15g of the coptis, 5~15g of mulberry leaf, semen plantaginis 10
5~15g of~20g and Radix Astragali.
Above-mentioned base case preferably, be made of the raw material of following parts by weight: radix angelicae sinensis 20g, Rhizoma Chuanxiong 15g, safflower
20g, ramulus cinnamomi 30g, wild chrysanthemum 30g, cordate houttuynia 10g, cassia seed 25g, seed of feather cockscomb 15g, Prunella vulgaris 25g, peppermint 5g, cortex moutan
15g, rhizoma anemarrhenae 20g, fructus lycii 15g, radix rehmanniae preparata 15, cortex cinnamomi 15, root of Chinese clematis 20g, Radix Salviae Miltiorrhizae 20g, pueraria lobata 30g, Radix Ophiopogonis 20g, Fructus Liquidambaris
25g, Sargent gloryvine 30g, folium artemisiae argyi 15g, fructus alpiniae oxyphyllae 20g, rhizoma polygonati 15g, Semen Cuscutae 20g, corydalis tuber 25g, achene of Siberian cocklebur 20g, coptis 10g, mulberry
Leaf 10g, semen plantaginis 15g and Radix Astragali 10g.
The invention also discloses the preparation methods of above-mentioned Chinese medicine composition, include the following steps:
(1) it is spare that each bulk pharmaceutical chemicals are weighed；
(2) 6~8 times of amount water of total raw material medicine are added to impregnate 1~2 hour, heating decocts 1~1.5 hour, and filtering, the dregs of a decoction are again
3~5 times of amount water are added, heating decocts 0.5~1 hour, and filtering, filtrate merges, and obtains supernatant；
(3) it is 1.05~1.06g/cm that supernatant, which is concentrated into relative density,3When, into spray dryer, inlet air temperature control
130~150 DEG C, 100~120 DEG C of leaving air temp, charging rate 3~5ml/ minutes, obtain spray dried powder.
The Chinese medicine composition is made stifling pack, handled via stifling instrument by the application of the traditional chinese medicine composition of the invention,
Stifling hot gas is obtained, for alleviating asthenopia.
Stifling pack is made in the spray dried powder by the application of Chinese medicine composition prepared by the method for the present invention, through smoked
Instrument processing is steamed, stifling hot gas is obtained, is applied to alleviate asthenopia.
The application of the traditional chinese medicine composition of the invention, the Chinese medicine composition after mixing, are added pharmaceutically acceptable auxiliary
Material, is made clinically-acceptable exterior-applied formulation.
The application of the traditional chinese medicine composition of the invention improves and slows down the purposes in blurring of image health medicine in preparation.
Each component raw material effect is as follows in Chinese medicine composition of the invention:
Radix angelicae sinensis: promoting blood circulation cures mainly that menostasis is obstructed and the illness of the stagnant swelling and pain of hemostasis.
Rhizoma Chuanxiong: promote breath and open depression, it is wet to dispel wind-dryness, promoting blood circulation and stopping pain.It is dizzy to cure mainly air-cooled headache rotation, hypochondriac pain abdomen pain, arthritis muscle contraction,
Menostasis, difficult labour, postpartum stasis block pain, ulcer sores.For irregular menstruation, amenorrhea and algomenorrhea, lump in the abdomen abdominal pain, pricking pain in the chest, fall flutter it is swollen
Bitterly, it has a headache, rheumatic arthralgia.
Safflower: there is the effect of blood circulation, removing blood stasis and acesodyne.For menostasis, dysmenorrhea, lochia, abdominal mass lump in the abdomen, thoracic obstruction
It is pained, stasis of blood, pricking pain in the chest, injury from falling down, sore swell and ache curative.
Ramulus cinnamomi: there is the effect of sweating expelling pathogenic factors from muscles and skin, warming meridian, help yang gas, flat and gas.It is usually used in anemofrigid cold, gastral cavity
Abdomen crymodynia, blood trembles with fear Amenorrhea, arthralgia, phlegm retention, oedema, palpitaition etc..
Wild chrysanthemum: cold nature has dispelling wind and heat from the body, subdhing swelling and detoxicating；Can treat furunculosis carbuncle swells, abscess of throat, wind-fire red eye,
The illnesss such as headache and dizziness.
Cordate houttuynia: acrid flavour, it is cold, it is distributed in lung channel.It can clearing heat and detoxicating, detumescence treatment sore, promoting urination and removing dampness, clearing away heat to cure dysentery, stomach invigorating
It helps digestion, is pulmonary abscess, sore swollen toxin, hemorrhoidal hemorrhage, the retention of heat in the spleen and stomach etc. suffered from real heat, heat toxin, damp evil, disease heat is controlled.Modern pharmacology
Experiment shows that this product has the effects that antibacterial, antiviral, raising immunity of organisms, diuresis.
Cassia seed: constipation and hyperlipidemia, hypertension are treated in relax bowel and defecation, lipid-loweringing improving eyesight；It clears liver and improve vision, sharp water defaecation,
There are laxative action, reducing blood pressure and blood fat.
The seed of feather cockscomb: clearing liver and improving vision, and moves back screen.For the hot hot eyes of liver, screen of looking unfamiliar film, blurring of vision, hepatopyretic vertigo.
Prunella vulgaris: relieve inflammation or internal heat improving eyesight the effect of, red eye, swell pain, headache etc. can be controlled.
Peppermint: property is pungent cool, sweating antipyretic medicine, can control influenza, headache, hot eyes, body heat, throat, gum swelling and pain etc.
Disease.External application can control neuralgia, pruitus, fash and eczema etc..Usually with peppermint for tea, clear away heart-fire improving eyesight.
Cortex moutan: tool clearing heat and cooling blood activates blood circulation and disperses blood clots, reducing the asthenic fever and other effects.The small toxicity of cortex moutan and paeonol.
Lycopodium calvatum: detumescence removes wind-warm syndrome.Infusing drugs in wine drink, relaxing tendons and activating collaterals.It eradicates depressed pain, damage, and internal injury caused by metallic tool removes phlegm
Sore subcutaneous ulcer soldier brothers are controlled in cough-relieving.
Rhizoma anemarrhenae: clearing heat-fire, nourishing Yin and moistening dryness.
Fructus lycii: nourishing the liver, nourshing kidney, moistening lung.Wolfberry leaf: qi-restoratives strengthening the essence, heat-clearing improving eyesight.
Radix rehmanniae preparata: yin-nourishing of enriching blood, life essence-filling, marrow-benefitting.
Cortex cinnamomi: waist and knee crymodynia is controlled in middle benefit gas kidney tonifying, eliminating cold to stop pain function, cold of insufficiency type and stomachache, chronic indigestion, and abdominal pain is vomited and diarrhoea,
It catches cold menostasis.Ramulus cinnamomi is there are also sweating expelling pathogenic factors from muscles and skin, warming meridian function, controls exogenous disease, chill, shoulder arm podomere and aches and other effects.
The root of Chinese clematis: root is used as medicine, can wind-damp dispelling, diuresis, promoting menstruation, analgesia, control damp and hot chill, migraines, jaundice edema, fish
Bone sticking larynx, waist and knee legs and feet crymodynia.And fresh strain energy treating acute tonsillitis, sphagitis；Filariasis is eradicated, toothache is controlled in external application.Complete stool
It can make pesticide, prevention and treatment bridging worm, cabbage caterpillar, cutworm, wriggler of going out etc..
The effect of Radix Salviae Miltiorrhizae: having promoting blood circulation, inducing meastruation to relieve menalgia, relieving restlessness and restlessness, cool blood to disappear carbuncle.For chest impediment and cardialgia, the stomach duct and abdomen side of body
Bitterly, a lump in the abdomen causing distension and pain, hot numbness pain, dysphoria and insomnia, irregular menstruation, dysmenorrhea menostasis, sore swell and ache curative.
Pueraria lobata: bringing down a fever with expelling pathogenic factors from muscles and skin, and promoting eruption promotes the production of body fluid to quench thirst, the function of Shengyang Zhixie.It is usually used in exterior syndrome to generate heat, stiff nape and back,
Measles without adequate eruption, pyreticosis is thirsty, and the deficiency of Yin is quenched one's thirst, and heat is purged heat dysentery, splenasthenic diarrhea.
Radix Ophiopogonis: major function nourishing Yin and promoting production of body fluid, moistening lung to arrest cough: few thirsty, the dry cough hemoptysis of saliva for lung-stomach yin deficiency；The heart-yin is not
The diseases such as the palpitation and being susceptible to fright and pyreticosis later period heat consuming body fluid of foot.Lung-Yin deficiency dry cough can be controlled with the root of straight ladybell, tendril-leaved fritillary bulb.
Fructus Liquidambaris: dispelling, collateral-activating, Li Shui, the effect of promoting menstruation.
Sargent gloryvine: sargentodoxa cuneata is the rattan of plants of Lardizabalaceae sargentodoxa cuneata.Bitter, property are returned flat.Return large intestine, Liver Channel.Tool removing toxic substances disappears
Carbuncle, promoting blood circulation and stopping pain, dispelling wind and eliminating dampness, disinsection efficiency.Cure mainly acute appendicitis, dysentery, cream pain, dysmenorrhea, menostasis, traumatic injury, rheumatic arthralgia,
Abdominal pain due to enterositosis.
Folium artemisiae argyi: warming channel for arresting bleeding, eliminating cold to stop pain；External application removing dampness to stop itchin.
Fructus alpiniae oxyphyllae: there is warming spleen and stopping diarrha the effect of taking the photograph saliva, warming up kidney reducing urination controlling nocturnal emission with astringent drugs.It is usually used in deficiency-cold in spleen and stomach, vomits, diarrhea,
Crymodynia in abdomen, the more salivas of mouth, enuresis with renal asthenia, frequent micturition, spermatorrhea, gonorrhoea.
Rhizoma polygonati: eye, tonifying liver gas, improving eyesight antivirus action are controlled.
Semen Cuscutae: it is sweet, warm, return kidney,liver,spleen to pass through, there is the effect of nourishing liver and kidney, astringent sperm contracting urine, miscarriage prevention, improving eyesight, antidiarrheal,
Begin to carry Shennong's Herbal, is listed in top grade.Sugariness generally has a tonic effect, sweet pungent tepor, reports gas and neutralizes, both can yang-tonifying,
Again can benefiting yin, have it is warm but not dry, mend without stagnant feature.Controlling nocturnal emission with astringent drugs miscarriage prevention and gonadotropic Effect.Chinese medicine thinks that kidney is congenital
Originally, interior residence Kidney-Yin and Yuanyang, are the root of human body reproductive development, the original power of internal organs functional activity.
Corydalis tuber: warm-natured, acrid flavour is bitter, enters the heart, spleen, liver, lung, is the quality goods of activating microcirculation and removing stasis medicinal, promoting qi circulation and relieving pain.
The achene of Siberian cocklebur: expelling cold, eliminating, clearing the nasal passage, wind-damp dispelling, analgesic.
The coptis: there is the effect of heat-clearing and damp-drying drug, purging fire for removing toxin.
Mulberry leaf: mulberry leaf have the effect of antibacterial anti-inflammatory, clearing heat and detoxicating.The DNJ minerals contained in mulberry leaf, energy ease constipation are logical
Just, improve constipation, effectively alleviate vivotoxin packing phenomenon.
Semen plantaginis: nature and flavor are sweet, cold, enter kidney, bladder, liver, lung channel, and function promoting diuresis for stranguria excreting dampness antidiarrheal, clears liver and improve vision, clearly
Thermalization phlegm is medicinal herbs most in use.
Radix Astragali: invigorating qi for strengthening superficies, pus draining and toxin expelling, diuresis, myogenic.For deficiency of vital energy and acking in strength, rush down prolapse of the anus for a long time, spontaneous perspiration, oedema, sub- official
Prolapsus, chronic rephrilis protinuria, diabetes, the long disunion of the open sore part.
Compared with prior art, the advantages and positive effects of the present invention are as follows:
Under instruction of Chinese Medicine theory, using the composition of Chinese medicine as raw material, using " liver kidney " and " heat clearing and blood circulation promoting " as argument
Medicine prescription is selected, asthenopia is alleviated in collaboration, significant in efficacy.The definition of " collaboration " of the invention can be understood as several medicinal material combinations
Afterwards, drug effect relative to raising when being used alone or has the function of new；Drug effect is more lasting；Composition in new prevention and treatment or
Healthcare field generates unexpected effect.
Improve the microcirculation of eye muscle, by the relationship between " liver kidney and the eye " of Chinese medicine state of internal organs theory and specific aim with heat-clearing
Improving eyesight, promoting blood circulation to remove blood stasis are therapy, deed prescription of starting with, to reach the therapeutic effect for alleviating visual fatigue；Pass through the conjunction of each Chinese medicine
Reason proportion, synergistic effect have significant curative effect to visual fatigue is alleviated, can take for a long time.
Specific embodiment
It elaborates below to specific embodiments of the present invention.
Embodiment 1
A kind of Traditional Chinese medicine composition for relieving asthenopia is made of the raw material of following parts by weight: radix angelicae sinensis 20g, Rhizoma Chuanxiong
15g, safflower 20g, ramulus cinnamomi 30g, wild chrysanthemum 30g, cordate houttuynia 10g, cassia seed 25g, seed of feather cockscomb 15g, Prunella vulgaris 25g, peppermint 5g,
Cortex moutan 15g, rhizoma anemarrhenae 20g, fructus lycii 15g, radix rehmanniae preparata 15, cortex cinnamomi 15, root of Chinese clematis 20g, Radix Salviae Miltiorrhizae 20g, pueraria lobata 30g, Radix Ophiopogonis 20g, road
Road leads to 25g, Sargent gloryvine 30g, folium artemisiae argyi 15g, fructus alpiniae oxyphyllae 20g, rhizoma polygonati 15g, Semen Cuscutae 20g, corydalis tuber 25g, achene of Siberian cocklebur 20g, the coptis
10g, mulberry leaf 10g, semen plantaginis 15g and Radix Astragali 10g.
The preparation method of above-mentioned Chinese medicine composition, includes the following steps:
(1) it is spare that each bulk pharmaceutical chemicals are weighed；
(2) 6 times of amount water of total raw material medicine are added to impregnate 1 hour, heating decocts 1 hour, and filtering, the dregs of a decoction add 3 times of amount water,
Heating decocts 0.5 hour, and filtering, filtrate merges, and obtains supernatant；
(3) it is 1.05g/cm that supernatant, which is concentrated into relative density,3When, into spray dryer, inlet air temperature controls 130 DEG C,
100 DEG C of leaving air temp, charging rate 3ml/ minutes, obtain spray dried powder.
Stifling pack is made in the spray dried powder, is handled through stifling instrument, stifling hot gas is obtained, is applied to alleviate view
Power fatigue.
Embodiment 2
A kind of Traditional Chinese medicine composition for relieving asthenopia is made of the raw material of following parts by weight: radix angelicae sinensis 30g, Rhizoma Chuanxiong
20g, safflower 30g, ramulus cinnamomi 40g, wild chrysanthemum 40g, cordate houttuynia 15g, cassia seed 35g, seed of feather cockscomb 20g, Prunella vulgaris 35g, peppermint
20g, cortex moutan 20g, rhizoma anemarrhenae 30g, fructus lycii 20g, radix rehmanniae preparata 20g, cortex cinnamomi 20g, root of Chinese clematis 30g, Radix Salviae Miltiorrhizae 30g, pueraria lobata 40g, Radix Ophiopogonis
30g, Fructus Liquidambaris 35g, Sargent gloryvine 40g, folium artemisiae argyi 20g, fructus alpiniae oxyphyllae 30g, rhizoma polygonati 20g, Semen Cuscutae 30g, corydalis tuber 35g, achene of Siberian cocklebur 30g,
5~15g of the coptis, 5~15g of 5~15g of mulberry leaf, 10~20g of semen plantaginis and Radix Astragali.
The preparation method of above-mentioned Chinese medicine composition, includes the following steps:
(1) it is spare that each bulk pharmaceutical chemicals are weighed；
(2) 8 times of amount water of total raw material medicine are added to impregnate 2 hours, heating decocts 1.5 hours, and filtering, the dregs of a decoction add 5 times of amounts
Water, heating decoct 1 hour, and filtering, filtrate merges, and obtain supernatant；
(3) it is 1.06g/cm that supernatant, which is concentrated into relative density,3When, into spray dryer, inlet air temperature controls 150 DEG C,
120 DEG C of leaving air temp, charging rate 5ml/ minutes, obtain spray dried powder.
Stifling pack is made in the spray dried powder, is handled through stifling instrument, stifling hot gas is obtained, is applied to alleviate view
Power fatigue.
Embodiment 3
A kind of Traditional Chinese medicine composition for relieving asthenopia is made of the raw material of following parts by weight: radix angelicae sinensis 10g, Rhizoma Chuanxiong
10g, safflower 10g, ramulus cinnamomi 20g, wild chrysanthemum 20g, cordate houttuynia 5g, cassia seed 15g, seed of feather cockscomb 10g, Prunella vulgaris 15g, peppermint 10g,
Cortex moutan 10g, rhizoma anemarrhenae 10g, fructus lycii 10g, radix rehmanniae preparata 10g, cortex cinnamomi 10g, root of Chinese clematis 10g, Radix Salviae Miltiorrhizae 10g, pueraria lobata 20g, Radix Ophiopogonis 10g,
Fructus Liquidambaris 15g, Sargent gloryvine 20g, folium artemisiae argyi 10g, fructus alpiniae oxyphyllae 10g, rhizoma polygonati 10g, Semen Cuscutae 10g, corydalis tuber 15g, achene of Siberian cocklebur 10g, the coptis
5g, mulberry leaf 5g, semen plantaginis 10g and Radix Astragali 5g.
Stifling pack is made in above-mentioned Chinese medicine composition, is handled through stifling instrument, stifling hot gas is obtained, is applied to alleviate view
Power fatigue.
The influence of Chinese medicine composition of the invention to SD rat breakup time of tear film is had studied below.
120 5~7 weeks SD rats are randomly divided into 4 groups, respectively low dose of Normal group, model control group, Chinese medicine
Amount group and Chinese medicine high dose group.Amino is respectively adopted in the mouse of model control group, Chinese medicine low dose group and Chinese medicine high dose group
Ethyl formate is twilight-sleep, later fixes mouse, pulls open eyelid, and with the pupil irradiation of cold light lamp face mouse, intensity of illumination is
4000Lx, duration 4h are repeated 2~5 days, until the symptom of conjunctival congestion occurs in mouse.Mouse dry eye model is built at this time
It stands successfully.
The mouse of Normal group is injected into distilled water daily, the mouse of model group injects distilled water daily, and low dose of Chinese medicine
Amount group injects the Chinese medicine composition (preparation of embodiment 1) of 20g/kg daily, and the mouse of Chinese medicine high dose group injects 40g/kg daily
Chinese medicine composition (preparation of embodiment 1), the administration time of this experiment is six days.
After administration, by Normal group, model control group, Chinese medicine low dose group and Chinese medicine high dose group mouse in crack
It is observed under lamp, records its breakup time of tear film, experiment is handled using blind.
Influence of the Chinese medicine composition of the invention of table 1 to mouse dry eyes
Via table 1 as can be seen that the mouse of Normal group and the mouse of model control group have in breakup time of tear film
Biggish difference, it is known that model foundation success, from the point of view of the comparison of model group and Chinese medicine group, using technical solution of the present invention Chinese medicine
After composition treats mouse, the breakup time of tear film of mouse is obviously prolonged, i.e., technical solution of the present invention has the dry eyes of mouse
Standby certain curative effect.
Observation on Clinical Application report
One, basic document (in July, 2017~2018 year December)
By randomly selecting volunteer participant 300, the Chinese medicine composition prepared to embodiment 1 is tried out, and every group 100
People, the age 18~45 years old, 27 years old average, male 168 people, 132 people of female, selected condition are as follows:
(1) simple eye or binocular vision is through logarithmic visual acuity chart inspection < 5.0；
(2) quickly computerized optometry after mydriasis, diopter is between -0.5D~3.0D；
(3) the organic illness of eye, amblyopia patient and hereditary myopia are excluded.
Two, application method
Stifling pack is made, is handled through stifling instrument, obtains stifling hot gas, for alleviating asthenopia, 1~2 time on the one,
A month as a course for the treatment of, 2~3 months courses for the treatment of of severe.
Taboo and points for attention:
1, no smoking and drinking during treating, avoids pungent stimulation food, pays attention to adjusting spirit, psychological pressure.
2, there is outer injury unusable.
3, pregnant woman disables.
Three, detection method
The stifling front and back of all subjects, respectively registers eye symptom, with without (0 point), light (1 point), in (2 points),
(3 points) classifications of weight, and counted with integrated value.
Visual fatigue symptom determination method (sxemiquantitative integration method)
Note: " random thoughts " refer to 1-2 times/2 days；
" when have " refers to 1-3 times/day；
" frequent " refers to > 3 times/day.
Four, subjective symptoms judgment criteria
Improve: having integral before stifling, integral is 0 after fumigating；There is an integral in stifling front and back, but it is stifling before integral subtract it is smoked
>=1 are integrated after steaming.
Invalid: stifling front and back integrates identical person；Integral, which is greater than, after stifling takes preceding integral person.
Five, it statisticallys analyze
Stifling front and back symptom improvement is counted with integrating, and treatment group and control group comparison among groups are examined with T.Six, result
Front-and rear-view fatigue symptom integral contrast is taken with significant difference P < 0.05 by treatment group；It is regarded between two groups after treatment tired
Labor symptom integral compares with significant difference P < 0.05, as a result prompts: there is the traditional chinese medicine composition of the invention improvement visual fatigue to make
With as a result see the table below 1.
2 treatment group of table and control group clinical symptoms integral
* it represents treatment group and compares P < 0.05 before and after treatment；Δ represents comparison among groups P < 0.05 after two groups of treatments.
Typical case
Case 1
Mrs Yang, female, 18 years old, student, left vision 0.3 before treating, right vision 0.4, left eye astigmatism, treatment time:
On December 20th, 2017, traditional Chinese medicine fumigating pack made of the method using embodiment 1 acted on upper palpebra inferior through stifling instrument so far
On, it treats 2 times within one day, a month course for the treatment of, the eyesight of eyes is gradually improving after 2 courses for the treatment of, hence it is evident that alleviate study
Pressure greatly caused by visual fatigue, school grade advances by leaps and bounds, follow-up so far there are no recurrence, and patient is very grateful.
Case 2
Man is opened, male, 48 years old, treatment time: professional on 2 1st, 2018, is made of the method for embodiment 1
Traditional Chinese medicine fumigating pack, acted on upper palpebra inferior through stifling instrument, one day treat 3 times, month three courses for the treatment of, by one treat
Eyes are limpid after journey, hence it is evident that caused visual fatigue of playing games are alleviated, without recurrence in 1 year.
Case 3
Mrs Chen, female, 24 years old, occupation: computer office worker faced computer work for a long time, and eyes are fuzzy, eye is swollen, dry and astringent, stream
Tear, eye socket are ached, treatment time: on September 20th, 2017, traditional Chinese medicine fumigating pack made of the method using embodiment 1, through fumigating instrument
Device obtains the steam stifling for alleviating asthenopia, cold compress gel is made in the steam stifling and medical accessory cooperation, then eye is cooperated to walk
Pearl type cold compress physiotherapy equipment rolls treatment 2 times, one for eye circumference in one day by Physical temperature-lowering relaxation effect on upper palpebra inferior
Month course for the treatment of is relieved the long-term radiation for facing computer, the dry and astringent distending pain symptom disappearance of eyes, eyes through two courses for the treatment of after
Eyesight also gradually changing, greatly improve work efficiency, 1 year no relapse of follow-up.
Above-described embodiment is only more excellent embodiment of the invention, is implemented according to the technical essence of the invention to above
Any simple modification, modification and the alternate variation that example is made, belong in the range of technical solution of the present invention.
Claims (7)
1. a kind of Traditional Chinese medicine composition for relieving asthenopia, which is characterized in that be made of the raw material of following parts by weight: radix angelicae sinensis 10
~30g, 10~20g of Rhizoma Chuanxiong, 10~30g of safflower, 20~40g of ramulus cinnamomi, 20~40g of wild chrysanthemum, 5~15g of cordate houttuynia, cassia seed 15
~35g, 10~20g of the seed of feather cockscomb, 15~35g of Prunella vulgaris, 10~20g of peppermint, 10~20g of cortex moutan, 10~30g of rhizoma anemarrhenae, fructus lycii
10~20g, 10~20g of radix rehmanniae preparata, 10~20g of cortex cinnamomi, 10~30g of the root of Chinese clematis, 10~30g of Radix Salviae Miltiorrhizae, 20~40g of pueraria lobata, Radix Ophiopogonis 10
~30g, 15~35g of Fructus Liquidambaris, 20~40g of Sargent gloryvine, 10~20g of folium artemisiae argyi, 10~30g of fructus alpiniae oxyphyllae, 10~20g of rhizoma polygonati, Semen Cuscutae
10~30g, 15~35g of corydalis tuber, 10~30g of the achene of Siberian cocklebur, 5~15g of the coptis, 5~15g of mulberry leaf, 10~20g of semen plantaginis and Radix Astragali 5
~15g.
2. a kind of Traditional Chinese medicine composition for relieving asthenopia according to claim 1, which is characterized in that by following parts by weight
Raw material composition: radix angelicae sinensis 20g, Rhizoma Chuanxiong 15g, safflower 20g, ramulus cinnamomi 30g, wild chrysanthemum 30g, cordate houttuynia 10g, cassia seed 25g, blueness
Feather cockscomb 15g, Prunella vulgaris 25g, peppermint 5g, cortex moutan 15g, rhizoma anemarrhenae 20g, fructus lycii 15g, radix rehmanniae preparata 15, cortex cinnamomi 15, root of Chinese clematis 20g, pellet
Join 20g, pueraria lobata 30g, Radix Ophiopogonis 20g, Fructus Liquidambaris 25g, Sargent gloryvine 30g, folium artemisiae argyi 15g, fructus alpiniae oxyphyllae 20g, rhizoma polygonati 15g, Semen Cuscutae 20g,
Corydalis tuber 25g, achene of Siberian cocklebur 20g, coptis 10g, mulberry leaf 10g, semen plantaginis 15g and Radix Astragali 10g.
3. a kind of preparation method of Traditional Chinese medicine composition for relieving asthenopia as claimed in claim 1 or 2, which is characterized in that
Include the following steps:
(1) it is spare that each bulk pharmaceutical chemicals are weighed；
(2) 6~8 times of amount water of total raw material medicine are added to impregnate 1~2 hour, heating decocts 1~1.5 hour, and filtering, the dregs of a decoction add 3
~5 times of amount water, heating decoct 0.5~1 hour, and filtering, filtrate merges, and obtain supernatant；
(3) it is 1.05~1.06g/cm that supernatant, which is concentrated into relative density,3When, into spray dryer, inlet air temperature control 130~
150 DEG C, 100~120 DEG C of leaving air temp, charging rate 3~5ml/ minutes, obtain spray dried powder.
4. a kind of application of Traditional Chinese medicine composition for relieving asthenopia as claimed in claim 1 or 2, which is characterized in that by institute
It states Chinese medicine composition and stifling pack is made, handled through stifling instrument, stifling hot gas is obtained, for alleviating asthenopia.
5. a kind of application of Traditional Chinese medicine composition for relieving asthenopia of preparation method preparation as claimed in claim 3, special
Sign is, stifling pack is made in the spray dried powder, is handled through stifling instrument, obtains stifling hot gas, is applied to alleviate view
Power fatigue.
6. a kind of application of Traditional Chinese medicine composition for relieving asthenopia as claimed in claim 1 or 2, which is characterized in that described
After mixing, pharmaceutically acceptable auxiliary material is added in Chinese medicine composition, and clinically-acceptable exterior-applied formulation is made.
7. a kind of Traditional Chinese medicine composition for relieving asthenopia of any of claims 1 or 2 improves and slows down the blurring of image in preparation
Purposes in health medicine.
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