CN108210373A - A kind of de-cutin shower dew and preparation method thereof - Google Patents

Abstract

The invention discloses a kind of de-cutin shower dew and preparation method thereof, it includes Thymol, the double poplar acid of water, ethyl alcohol, propylene glycol, lauric acid, myristic acid, palmitic acid, potassium hydroxide, glycol distearate, sulfosuccinic acid ethylhexyl sodium, Cocoamidopropyl betaine, sodium cocoyl glycinate, polyquaternium 7, polyglyceryl fatty acid ester composition, tetrasodium ethylenediamine tetraacetate, sodium chloride, low-carbon alcohols, essence, preservative, water, squalene, vitamin B and tea oil extract, de-cutin shower of the present invention reveals mild pro-skin, it can effective anti-bacteria wet keeping, effective whitening exfoliating, particularly suitable for there is the crowd of skin itching and body moss use.

Description

A kind of de-cutin shower dew and preparation method thereof

Technical field

The invention belongs to de-cutin shower dew articles for use fields, and in particular to a kind of de-cutin shower dew and preparation method thereof.

Background technology

Shower cream is also known as bath oil, refers to a kind of liquid ceanser used when having a bath, is that a kind of modern is common Cleaning supplies, the invention of bath oil is primarily to the sense of touch and effect of substitution tradition cleaning soap.

Bath oil does not have very hard feeling as soap, the effect of amino acid bath foam when contacting people's skin Especially apparent, amino acid de-cutin shower is showed one's true colours relatively low for the de-cutin shower dew pH value of raw material compared with Sulfates surfactant A bit, mild moisturizing will not cause strong acid-base to stimulate skin.

The antibacterial effect of traditional de-cutin shower dew is to be improved, particularly to the resistance of staphylococcus aureus not Foot, while also there is a situation where that moistening effect is bad, traditional de-cutin shower dew is especially in the presence of whitening exfoliating ability not The problem of sufficient, how to improve de-cutin shower dew anti-bacteria wet keeping effect make its nonirritant again and also can with whitening exfoliating into Technological difficulties for this field.

Invention content

The purpose of the present invention is to provide a kind of de-cutin shower dew, can effective anti-bacteria wet keeping, particularly suitable for there is skin The crowd of skin itching and body moss uses.

The present invention is by the following technical programs to realize above-mentioned purpose, and a kind of de-cutin shower reveals, including following weight The component of percentages：Thymol 0.1 ~ 0.5%, ethyl alcohol 0.2 ~ 1%, propylene glycol 0.5 ~ 3.5%, lauric acid 2 ~ 8%, myristic acid 4 ~ 9%, palmitic acid 2 ~ 8%, potassium hydroxide 1.5 ~ 6%, glycol distearate 1 ~ 2%, sulfosuccinic acid ethylhexyl sodium 1 ~ 5%th, Cocoamidopropyl betaine 3 ~ 7%, sodium cocoyl glycinate 1 ~ 5%, polyquaternium -7 0.1 ~ 1.5%, polyglycerol fatty acid Ester composition 0.3 ~ 3%, tetrasodium ethylenediamine tetraacetate 0.1 ~ 1%, sodium chloride 0.2 ~ 1.5%, essence 0.2 ~ 1%, water 30 ~ 80%, Shuan Shui Poplar acid 0.1 ~ 0.5%, low-carbon alcohols 0.1 ~ 1%, squalene 0.1 ~ 1%, vitamin B 0.3 ~ 1%, tea oil extract 0.1 ~ 1% and anti-corrosion Agent 0.1 ~ 0.3%.

Preferably, the preservative is Phenoxyethanol.

Preferably, the polyglyceryl fatty acid ester composition includes -4 certain herbaceous plants with big flowers acid esters of -6 caprylate of polyglycereol and polyglycereol.

Preferably, the de-cutin shower dew further includes plant extracts 0.2 ~ 2.0%.

A kind of method for preparing de-cutin shower dew, includes the following steps：

（1）Thymol, salicyl salicylate (salsalate) are added in be dissolved to transparent in ethyl alcohol, add plant extracts, propylene glycol stir to It is fully transparent, bactericidal composition is prepared into, it is spare；

（2）Potassium hydroxide is added in into the water of component weight 45 ~ 55% to dissolve and stir evenly, and then adds in lauric acid, Pork and beans Cool acid, palmitic acid ethylene glycol distearyl acid, sulfosuccinic acid ethylhexyl sodium, are persistently stirred and heated to 75 DEG C, insulation reaction 25~35min；

（3）After the completion of reaction, Cocoamidopropyl betaine, polyglyceryl fatty acid ester composition are added in, and stir evenly, system 55 DEG C are cooled to, adds in sodium cocoyl glycinate, polyquaternium -7, and stir evenly；

（4）System is cooled to 35 DEG C, and tetrasodium ethylenediamine tetraacetate, sodium chloride, low-carbon alcohols, essence, stirring are then added in into system To being completely dissolved；

（5）Enter step（1）Bactericidal composition, stir evenly, be eventually adding preservative, water, squalene, vitamin B and tea oil Extract stirs evenly.

Plant extracts of the present invention contains 55% camellia flower extract, 25% Honegsukle flower P.E and 20% Camphorated oil has good antibacterial and bacteriostasis.De-cutin shower of the present invention dew is particularly suitable for having skin itching and body moss Crowd uses.

The composition of low-carbon alcohols, vitamin B and tea oil extract protrudes the effect of whitening exfoliating.

Advantageous effect：De-cutin shower dew antibacterial effect of the present invention is strong, and the killing rate of staphylococcus aureus is reached 99.9%；De-cutin shower dew moisture-keeping efficacy of the present invention is remarkable；De-cutin shower dew anti-bacteria wet keeping effect of the present invention is good, while this Invention shower is nonirritant, particularly can be with whitening exfoliating.

Specific embodiment

The present invention is further described, but the present invention is not limited only to following embodiment below by way of specific embodiment. In the scope of the present invention or present disclosure is not being departed from, in spirit and scope, to de-cutin shower of the present invention Dew and preparation method thereof is suitably modified, replaces the identical component of effect, is aobvious and easy to those skilled in the art See, they are considered as being included within the scope of the present invention.

Embodiment 1：

A kind of de-cutin shower dew includes the component of following weight percent meter：Thymol 0.25%, ethyl alcohol 0.6%, propylene glycol 2%th, lauric acid 5%, myristic acid 7%, palmitic acid 5%, potassium hydroxide 3.5%, glycol distearate 1.5%, sulfosuccinic acid Ethylhexyl sodium 3%, Cocoamidopropyl betaine 5%, sodium cocoyl glycinate 3%, polyquaternium -7 0.8%, polyglycerol ester Fat acid ester composite 1.7%, tetrasodium ethylenediamine tetraacetate 0.5%, sodium chloride 0.8%, essence 0.6%, water 65%, sour 0.25 low-carbon alcohols 0.55 squalene 0.6,0.6% tea oil extract 0.5 of vitamin B and preservative described in preservative 0.19% are Phenoxyethanol；Institute It states polyglyceryl fatty acid ester composition and includes -4 certain herbaceous plants with big flowers of -6 caprylate of polyglycereol and polyglycereol；The de-cutin shower dew further includes plant Object extract 1%.

A kind of method for preparing de-cutin shower dew, includes the following steps：

（1）Thymol, salicyl salicylate (salsalate) are added in be dissolved to transparent in ethyl alcohol, add plant extracts, propylene glycol stir to It is fully transparent, bactericidal composition is prepared into, it is spare；

（2）Potassium hydroxide is added in into the water of component weight 45 ~ 55% to dissolve and stir evenly, and then adds in lauric acid, Pork and beans Cool acid, palmitic acid ethylene glycol distearyl acid, sulfosuccinic acid ethylhexyl sodium, are persistently stirred and heated to 75 DEG C, insulation reaction 25~35min；

（3）After the completion of reaction, Cocoamidopropyl betaine, polyglyceryl fatty acid ester composition are added in, and stir evenly, system 55 DEG C are cooled to, adds in sodium cocoyl glycinate, polyquaternium -7, and stir evenly；

（4）System is cooled to 35 DEG C, and tetrasodium ethylenediamine tetraacetate, sodium chloride, low-carbon alcohols, essence, stirring are then added in into system To being completely dissolved；

（5）Enter step（1）Bactericidal composition, stir evenly, be eventually adding preservative, water, squalene, vitamin B and tea oil Extract stirs evenly.

Embodiment 2：

A kind of de-cutin shower dew includes the component of following weight percent meter：Thymol 0.1%, ethyl alcohol 0.2%, propylene glycol 0.5%th, lauric acid 2%, myristic acid 4%, palmitic acid 2%, potassium hydroxide 1.5%, glycol distearate 1%, sulfosuccinic acid Ethylhexyl sodium 1%, Cocoamidopropyl betaine 3%, sodium cocoyl glycinate 1%, polyquaternium -7 0.1%, polyglycerol ester Fat acid ester composite 0.3%, tetrasodium ethylenediamine tetraacetate 0.1%, sodium chloride 0.2%, essence 0.2%, water 30%, salicyl salicylate (salsalate) 0.1%, Low-carbon alcohols 0.1%, squalene 0.1%, vitamin B 0.3%, tea oil extract 0.1% and preservative 0.1%；The preservative is benzene Oxyethanol；The polyglyceryl fatty acid ester composition includes -4 certain herbaceous plants with big flowers acid esters of -6 caprylate of polyglycereol and polyglycereol；The exfoliating Shower cream further includes plant extracts 0.2%.

The method of de-cutin shower dew is prepared with embodiment 1.

Embodiment 3：

A kind of de-cutin shower dew includes the component of following weight percent meter：Thymol 0.5%, ethyl alcohol 1%, propylene glycol 3.5%th, lauric acid 8%, myristic acid 9%, palmitic acid 8%, potassium hydroxide 6%, glycol distearate 2%, sulfosuccinic acid two Ethylhexyl sodium 5%, Cocoamidopropyl betaine 7%, sodium cocoyl glycinate 5%, polyquaternium -7 1.5%, polyglycereol fat Acid ester composite 3%, tetrasodium ethylenediamine tetraacetate 1%, sodium chloride 1.5%, essence 1%, water 80%, salicyl salicylate (salsalate) 0.5%, low-carbon alcohols 1%th, squalene 1%, vitamin B 1%, tea oil extract 1% and preservative 0.3%；The preservative is Phenoxyethanol；It is described poly- Fatty acid glyceride composition includes -4 certain herbaceous plants with big flowers acid esters of -6 caprylate of polyglycereol and polyglycereol；The de-cutin shower dew further includes plant Object extract 2.0%.

The method of de-cutin shower dew is prepared with embodiment 1.

Comparative example 1：

Plant extracts is become 0 from 15g, Thymol is from 2.5g becomes 10g, salicyl salicylate (salsalate) becomes 10g from 2.5g, other groups Divide and prepare with embodiment 1.

Comparative example 2：

Thymol is become into 0, salicyl salicylate (salsalate) from 2.5g and becomes 0 from 2.5g, plant extracts becomes 20g, other components from 15g With preparation with embodiment 1.

Comparative example 3：

Polyglyceryl fatty acid ester composition is become 0 from 10g, squalene becomes 15g from 5g, other components and prepares same embodiment 1。

Comparative example 4：

Squalene is become into 0g from 5g, polyglyceryl fatty acid ester composition becomes 15 from 10g, other components and prepares same embodiment 1。

Test example one：

The anti-microbial property test of de-cutin shower dew of the present invention

According to GB19877.2-2005《Extraordinary bath agent》Measure exfoliating prepared by the embodiment of the present invention 1 ~ 3 and comparative example 1 ~ 2 The antibacterial effect of shower cream, result such as the following table 1：

The antibacterial effect of 1 de-cutin shower of the present invention of table dew

It can be obtained by upper table 1, the good anti-bacterial effect of 1 ~ 3 de-cutin shower of embodiment of the present invention dew kills staphylococcus aureus Rate of going out reaches up to 99.85%《Extraordinary bath agent》The requirement of antibiotic rate >=90% in standard, therefore de-cutin shower of the present invention dew reaches The sterilizing rate highest of the rank, wherein embodiment 1 revealed to antibacterial de-cutin shower illustrates that 1 each component of embodiment and proportioning cooperate with Effect is most strong.It is only carried in 1 de-cutin shower of comparative example dew without plant extracts, 2 de-cutin shower of comparative example dew containing plant Object is taken, sterilizing rate will be low compared to embodiment 1 ~ 3, illustrates plant extracts of the present invention and Thymol and salicyl salicylate (salsalate) In the presence of very strong synergistic effect, three's compounding can play very strong antibacterial action.

Test example two：

The irritation test of de-cutin shower dew of the present invention

According to《Cosmetics health specification》（Version in 2007）Skin irritation/corrosion test is to embodiment 1 and comparative example 3 ~ 4 De-cutin shower dew carries out dermoreaction scoring, and concrete operations are as follows：

1st, experimental animal：Healthy white rabbit 12, female, 1.8 ~ 2.2kg, skin zero damage are divided into 3 groups, every group 4.

2nd, experimental procedure：

Experiment white rabbit back backbone diamond wool is cut for 24 hours before 2.1 experiments, do not damage epidermis, unhairing range or so be respectively 3cm × 3cm。

2.2 take tested material（That is embodiment 1 and 3 ~ 4 de-cutin shower of comparative example dew）0.5g is coated directly on skin, then With two layers of gauze（2.5cm×2.5cm）It is covered with one layer of glassine paper, then fixed with nonirritant adhesive plaster and bandage.It is another Side skin is as control.Using blocking test, application 2h.After the test residual tested material is removed with warm water.

Position dermoreaction is smeared in 2.3 1,24, the 48 and 72h observations after tested material is removed, and it is anti-to carry out skin by table 2 Should score, overall merit is carried out with the average value of animal subject integration, according to for 24 hours, 48h and 72h respectively observe time point top Mean value judges skin irritatin intensity by table 3.

2 skin wound repair of table scores

Dermoreaction	Integration
		Erythema and eschar are formed
Without erythema	0
		Slight erythema（It is visible reluctantly）	2
Apparent erythema	1
		Moderate ~ severe erythema	2
Severe erythema（Aubergine）It is formed to slight eschar	3
Oedema is formed
		Without oedema	0
Slight oedema（It is visible reluctantly）	1
		Mild edema（Cutaneous protuberance is clearly outlined）	1
Intermediate edema（Cutaneous protuberance 1mm）	2
		Severe edema（Cutaneous protuberance is more than 1mm, and range expands）	3
Top	8

3 skin irritatin strength grading of table

Integral mean value	Intensity
		0~<0.5	It is nonirritant
0.5~<2.0	Subexcite
		2.0~<6.0	Moderate stimulation
6.0~8.0	Strong and stimulating

3rd, experimental result：It see the table below 4

The irritation test result of 4 de-cutin shower of the present invention of table dew

It can be obtained by upper table 4, de-cutin shower dew of the present invention works as to no skin irritation and lacks -6 octanoic acid of polyglycereol in system When ester, -4 certain herbaceous plants with big flowers acid esters of polyglycereol and -3 cocounut oil acid esters of polyglycereol（That is comparative example 3）, the irritation of de-cutin shower dew enhances, right Skin generates moderate stimulation, causes erythema and oedema；And when lacking squalene in system（That is comparative example 4）, exfoliating The irritation of shower cream also has slight enhancing, illustrates -6 caprylate of polyglycereol, -4 certain herbaceous plants with big flowers acid esters of polyglycereol and -3 coconut oil of polyglycereol The polyglyceryl fatty acid ester composition of ester compounding is indispensable in the technical solution of the present invention, and the collaboration of three's ingredient can significantly drop Low formula irritation, then coordinate squalene, further reduce irritation of the system to skin.

Test example three:

The moistening effect test of de-cutin shower dew of the present invention

1st, trial target：De-cutin shower dew prepared by the embodiment of the present invention 1 ~ 3 and comparative example 3.

2nd, tested crowd

Number：32 people

Age：Between 24 ~ 30 years old

Gender：20 people of female, male 12 people

Grouping：It is divided into 4 groups, every group of 5 people of female, male 3 people.

Health status：Subjects skin's health, no skin disease allergies meet subject and volunteer inclusion criteria.

3rd, test method：In 5 square centimeters of position of volunteer's right hand inner forearm, test zone is drawn, is surveyed with moisture Examination instrument test respectively washing before skin water content and washing 2 hours after moisture content of skin, it is increased to calculate water content Percentage %.

4th, test result：It see the table below 5.

The moistening effect test result of 5 de-cutin shower of the present invention of table dew

Project	Moisture content of skin before washing	Moisture content of skin after washing 2 hours	Water content increases percentage %
				Embodiment 1	35.24	43.91	24.64
Embodiment 2	36.88	45.51	23.52
				Embodiment 3	35.80	44.12	23.14
Comparative example 3	35.57	40.22	13.14

It can be obtained by upper table 5, the moistening effect of de-cutin shower dew of the present invention is good, and moisture content of skin increases percentage after washing 2 hours Rate is especially best with the moistening effect of embodiment 1 more than 23%, reaches 24.6%, each component synergistic effect is most strong；Embodiment simultaneously 1 ~ 3 compared with comparative example 3, and water content increases percentage and improves about 10%, illustrate -6 caprylate of polyglycereol of the present invention, polyglycereol - 4 certain herbaceous plants with big flowers acid esters and the polyglyceryl fatty acid ester composition of -3 cocounut oil acid esters of polyglycereol compounding can not only reduce the irritation of system, also The performance of keeping humidity of system can be effectively improved, alleviates skin tight feeling after taking a shower.

It the above is only the preferred embodiment of the present invention, it is noted that above-mentioned preferred embodiment is not construed as pair The limitation of the present invention, protection scope of the present invention should be subject to claim limited range.For the art For those of ordinary skill, without departing from the spirit and scope of the present invention, several improvements and modifications can also be made, these change Protection scope of the present invention is also should be regarded as into retouching.

Claims (5)

1. a kind of de-cutin shower dew includes the component of following weight percent meter：Thymol 0.1 ~ 0.5%, ethyl alcohol 0.2 ~ 1%th, propylene glycol 0.5 ~ 3.5%, lauric acid 2 ~ 8%, myristic acid 4 ~ 9%, palmitic acid 2 ~ 8%, potassium hydroxide 1.5 ~ 6%, ethylene glycol two Stearate 1 ~ 2%, sulfosuccinic acid ethylhexyl sodium 1 ~ 5%, Cocoamidopropyl betaine 3 ~ 7%, sodium cocoyl glycinate 1 ~ 5%, polyquaternium -7 0.1 ~ 1.5%, polyglyceryl fatty acid ester composition 0.3 ~ 3%, tetrasodium ethylenediamine tetraacetate 0.1 ~ 1%, chlorine Change sodium 0.2 ~ 1.5%, essence 0.2 ~ 1%, water 30 ~ 80%, which is characterized in that further include salicyl salicylate (salsalate) 0.1 ~ 0.5%, low-carbon alcohols 0.1 ~ 1%th, squalene 0.1 ~ 1%, vitamin B 0.3 ~ 1%, tea oil extract 0.1 ~ 1% and preservative 0.1 ~ 0.3%.

2. de-cutin shower dew as described in claim 1, which is characterized in that the preservative is Phenoxyethanol.

3. de-cutin shower dew as described in claim 1, which is characterized in that the polyglyceryl fatty acid ester composition includes poly- - 4 certain herbaceous plants with big flowers acid esters of -6 caprylate of glycerine and polyglycereol.

4. de-cutin shower dew as described in claim 1, which is characterized in that the de-cutin shower dew further includes plant extract Object 0.2 ~ 2.0%.

A kind of 5. method of de-cutin shower dew prepared as described in claim 1 ~ 4 is any, which is characterized in that including following step Suddenly：

（1）Thymol, salicyl salicylate (salsalate) are added in be dissolved to transparent in ethyl alcohol, add plant extracts, propylene glycol stir to It is fully transparent, bactericidal composition is prepared into, it is spare；

（2）Potassium hydroxide is added in into the water of component weight 45 ~ 55% to dissolve and stir evenly, and then adds in lauric acid, Pork and beans Cool acid, palmitic acid ethylene glycol distearyl acid, sulfosuccinic acid ethylhexyl sodium, are persistently stirred and heated to 75 DEG C, insulation reaction 25~35min；

（3）After the completion of reaction, Cocoamidopropyl betaine, polyglyceryl fatty acid ester composition are added in, and stir evenly, system 55 DEG C are cooled to, adds in sodium cocoyl glycinate, polyquaternium -7, and stir evenly；

（4）System is cooled to 35 DEG C, and tetrasodium ethylenediamine tetraacetate, sodium chloride, low-carbon alcohols, essence, stirring are then added in into system To being completely dissolved；

（5）Enter step（1）Bactericidal composition, stir evenly, be eventually adding preservative, water, squalene, vitamin B and tea oil Extract stirs evenly.