CN108186376A - A kind of small-micelle water alcohol-free toner and preparation method thereof, cosmetics - Google Patents
A kind of small-micelle water alcohol-free toner and preparation method thereof, cosmetics Download PDFInfo
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- CN108186376A CN108186376A CN201810223541.9A CN201810223541A CN108186376A CN 108186376 A CN108186376 A CN 108186376A CN 201810223541 A CN201810223541 A CN 201810223541A CN 108186376 A CN108186376 A CN 108186376A
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- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 title claims abstract description 75
- 239000000693 micelle Substances 0.000 title claims abstract description 48
- 238000002360 preparation method Methods 0.000 title claims abstract description 17
- 239000002537 cosmetic Substances 0.000 title claims abstract description 9
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims abstract description 30
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims abstract description 18
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 claims abstract description 10
- 241000736199 Paeonia Species 0.000 claims abstract description 10
- 235000006484 Paeonia officinalis Nutrition 0.000 claims abstract description 10
- NOOLISFMXDJSKH-UTLUCORTSA-N (+)-Neomenthol Chemical compound CC(C)[C@@H]1CC[C@@H](C)C[C@@H]1O NOOLISFMXDJSKH-UTLUCORTSA-N 0.000 claims abstract description 9
- KIUKXJAPPMFGSW-DNGZLQJQSA-N (2S,3S,4S,5R,6R)-6-[(2S,3R,4R,5S,6R)-3-Acetamido-2-[(2S,3S,4R,5R,6R)-6-[(2R,3R,4R,5S,6R)-3-acetamido-2,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-2-carboxy-4,5-dihydroxyoxan-3-yl]oxy-5-hydroxy-6-(hydroxymethyl)oxan-4-yl]oxy-3,4,5-trihydroxyoxane-2-carboxylic acid Chemical compound CC(=O)N[C@H]1[C@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@H](O[C@H]2[C@@H]([C@@H](O[C@H]3[C@@H]([C@@H](O)[C@H](O)[C@H](O3)C(O)=O)O)[C@H](O)[C@@H](CO)O2)NC(C)=O)[C@@H](C(O)=O)O1 KIUKXJAPPMFGSW-DNGZLQJQSA-N 0.000 claims abstract description 9
- NOOLISFMXDJSKH-UHFFFAOYSA-N DL-menthol Natural products CC(C)C1CCC(C)CC1O NOOLISFMXDJSKH-UHFFFAOYSA-N 0.000 claims abstract description 9
- VTAJIXDZFCRWBR-UHFFFAOYSA-N Licoricesaponin B2 Natural products C1C(C2C(C3(CCC4(C)CCC(C)(CC4C3=CC2)C(O)=O)C)(C)CC2)(C)C2C(C)(C)CC1OC1OC(C(O)=O)C(O)C(O)C1OC1OC(C(O)=O)C(O)C(O)C1O VTAJIXDZFCRWBR-UHFFFAOYSA-N 0.000 claims abstract description 9
- 235000011187 glycerol Nutrition 0.000 claims abstract description 9
- LPLVUJXQOOQHMX-UHFFFAOYSA-N glycyrrhetinic acid glycoside Natural products C1CC(C2C(C3(CCC4(C)CCC(C)(CC4C3=CC2=O)C(O)=O)C)(C)CC2)(C)C2C(C)(C)C1OC1OC(C(O)=O)C(O)C(O)C1OC1OC(C(O)=O)C(O)C(O)C1O LPLVUJXQOOQHMX-UHFFFAOYSA-N 0.000 claims abstract description 9
- 229960004949 glycyrrhizic acid Drugs 0.000 claims abstract description 9
- UYRUBYNTXSDKQT-UHFFFAOYSA-N glycyrrhizic acid Natural products CC1(C)C(CCC2(C)C1CCC3(C)C2C(=O)C=C4C5CC(C)(CCC5(C)CCC34C)C(=O)O)OC6OC(C(O)C(O)C6OC7OC(O)C(O)C(O)C7C(=O)O)C(=O)O UYRUBYNTXSDKQT-UHFFFAOYSA-N 0.000 claims abstract description 9
- 239000001685 glycyrrhizic acid Substances 0.000 claims abstract description 9
- 235000019410 glycyrrhizin Nutrition 0.000 claims abstract description 9
- LPLVUJXQOOQHMX-QWBHMCJMSA-N glycyrrhizinic acid Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@@H]1O[C@@H]1C([C@H]2[C@]([C@@H]3[C@@]([C@@]4(CC[C@@]5(C)CC[C@@](C)(C[C@H]5C4=CC3=O)C(O)=O)C)(C)CC2)(C)CC1)(C)C)C(O)=O)[C@@H]1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O LPLVUJXQOOQHMX-QWBHMCJMSA-N 0.000 claims abstract description 9
- 229920002674 hyaluronan Polymers 0.000 claims abstract description 9
- 229960003160 hyaluronic acid Drugs 0.000 claims abstract description 9
- 229940041616 menthol Drugs 0.000 claims abstract description 9
- 235000015112 vegetable and seed oil Nutrition 0.000 claims abstract description 9
- FYGDTMLNYKFZSV-URKRLVJHSA-N (2s,3r,4s,5s,6r)-2-[(2r,4r,5r,6s)-4,5-dihydroxy-2-(hydroxymethyl)-6-[(2r,4r,5r,6s)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1[C@@H](CO)O[C@@H](OC2[C@H](O[C@H](O)[C@H](O)[C@H]2O)CO)[C@H](O)[C@H]1O FYGDTMLNYKFZSV-URKRLVJHSA-N 0.000 claims abstract description 7
- 229920002498 Beta-glucan Polymers 0.000 claims abstract description 7
- 238000003756 stirring Methods 0.000 claims description 23
- 206010008570 Chloasma Diseases 0.000 claims description 9
- 208000003351 Melanosis Diseases 0.000 claims description 9
- 230000037303 wrinkles Effects 0.000 claims description 8
- 238000005481 NMR spectroscopy Methods 0.000 claims description 5
- 230000002378 acidificating effect Effects 0.000 claims description 4
- 239000000203 mixture Substances 0.000 claims description 4
- 239000008236 heating water Substances 0.000 claims description 3
- 230000036541 health Effects 0.000 claims description 2
- 150000004676 glycans Chemical class 0.000 claims 1
- 150000003384 small molecules Chemical class 0.000 claims 1
- 210000004927 skin cell Anatomy 0.000 abstract description 14
- 230000003020 moisturizing effect Effects 0.000 abstract description 13
- 230000004060 metabolic process Effects 0.000 abstract description 4
- 238000010521 absorption reaction Methods 0.000 abstract description 3
- 239000002904 solvent Substances 0.000 abstract description 3
- 239000003153 chemical reaction reagent Substances 0.000 abstract description 2
- 239000000470 constituent Substances 0.000 abstract description 2
- 231100000252 nontoxic Toxicity 0.000 abstract description 2
- 230000003000 nontoxic effect Effects 0.000 abstract description 2
- 210000003491 skin Anatomy 0.000 description 31
- 230000000694 effects Effects 0.000 description 8
- 208000024891 symptom Diseases 0.000 description 7
- 239000012153 distilled water Substances 0.000 description 6
- 241000283973 Oryctolagus cuniculus Species 0.000 description 4
- 210000004027 cell Anatomy 0.000 description 4
- 239000011148 porous material Substances 0.000 description 4
- 206010067484 Adverse reaction Diseases 0.000 description 3
- 206010027146 Melanoderma Diseases 0.000 description 3
- 230000006838 adverse reaction Effects 0.000 description 3
- 230000032683 aging Effects 0.000 description 3
- 239000003795 chemical substances by application Substances 0.000 description 3
- 238000005516 engineering process Methods 0.000 description 3
- 230000002427 irreversible effect Effects 0.000 description 3
- 238000005507 spraying Methods 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- 208000010201 Exanthema Diseases 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 210000000170 cell membrane Anatomy 0.000 description 2
- 230000019522 cellular metabolic process Effects 0.000 description 2
- 201000005884 exanthem Diseases 0.000 description 2
- 230000006872 improvement Effects 0.000 description 2
- 235000019198 oils Nutrition 0.000 description 2
- 206010037844 rash Diseases 0.000 description 2
- 230000009759 skin aging Effects 0.000 description 2
- 108091006146 Channels Proteins 0.000 description 1
- 229920001503 Glucan Polymers 0.000 description 1
- 108090000862 Ion Channels Proteins 0.000 description 1
- 102000004310 Ion Channels Human genes 0.000 description 1
- 240000005001 Paeonia suffruticosa Species 0.000 description 1
- 235000003889 Paeonia suffruticosa Nutrition 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 238000009412 basement excavation Methods 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 235000009508 confectionery Nutrition 0.000 description 1
- 239000003651 drinking water Substances 0.000 description 1
- 235000020188 drinking water Nutrition 0.000 description 1
- 239000000686 essence Substances 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 239000006210 lotion Substances 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 238000002604 ultrasonography Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/82—Preparation or application process involves sonication or ultrasonication
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Dermatology (AREA)
- Chemical & Material Sciences (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Inorganic Chemistry (AREA)
- Gerontology & Geriatric Medicine (AREA)
- Cosmetics (AREA)
Abstract
The invention belongs to contain inorganic constituents technical field, a kind of small-micelle water alcohol-free toner and preparation method thereof, cosmetics are disclosed, are made of according to parts by weight 0.05 part 3 parts of 80 parts 97 parts of small-micelle water, 0.01 part 5 parts of glycerine, 0.01 part 5 parts of D-sorbite, 0.05 part 3 parts of glycyrrhizic acid diformazan, 0.01 part 1 part of hyaluronic acid, 0.05 part 0.5 part of menthol, 0.05 part 5 parts of beta glucan, 0.05 part 1 part of peony seed oil and citric acid.For the present invention using micromolecular water as solvent, hydrone smaller can be more conducive to absorption of the Skin Cell to moisture, can effectively facilitate the metabolism of Skin Cell, have better moisturizing moisturizing effect.And the addition moisturizing used and functional addition reagent, it is nontoxic, more mildly, Skin Cell is not damaged, compared with common toner, more mildly.
Description
Technical field
The invention belongs to contain inorganic constituents technical field more particularly to a kind of small-micelle water alcohol-free toner and its preparation
Method, cosmetics.
Background technology
At present, the prior art commonly used in the trade is such：Toner generally also by person for firming lotion or toner etc.,
It, which has, adjusts skin PH balances, and cleaning skin pore dirt keeps the skin wet, the effect of cutin-softening.Currently on the market refreshing
Skin water type is in the majority, in order to reduce cost, using cheap raw material, and adds more chemical addition agent, this toner is outstanding
It is more not suitable for for sensitive.In toner formula, substantially more than 90% is all water, the moisture generally used
Son comes from distilled water, and this distilled water was formed for 13-15 with last water clusters, and the average diameter of molecule is 2.6nm, for a long time
A diameter of 6nm after being long placed in, it is difficult into cell, be absorbed by cell.Nobel chemistry award-winner drape over one's shoulders moral Ah Gray within 2003,
Successfully take cell membrane hydrophilic channel high definition stereoscopic photograph, it was confirmed that the cell membrane that Dr.Erwincher is proposed has 2nm and leads to
The report in road.Most of common daily drinking water, distilled water, pure water are macromolecular mass water, and water clusters water is at 13-15
More than, nuclear magnetic resonance half-amplitude duration value is 110-130Hz or so, and diameter is more than 2nm, it is difficult to be absorbed.Small-micelle water, it by
5-7 hydrone rearranges, and nuclear magnetic resonance half-amplitude duration value is 70Hz or so.Molecular diameter is less than 2nm, it is easier in cell
It is passed in and out in membrane channels, is more advantageous to the absorption of cell.Most of main component water on existing market in common toner is adopted
With distilled water, water clusters water is arranged by 13-15 or more hydrone, and molecular diameter is more than 2nm, it is difficult to is absorbed by the skin, be protected
Wet moisturizing effect is poor, and chemical addition agent is more in toner, and irreversible influence is easily caused on skin, hinders Skin Cell
Metabolism damages Skin Cell, causes the adverse reactions such as clogging of pores, chloasma, blackspot, fash.
In conclusion problem of the existing technology is：Common toner is difficult to be absorbed by the skin on existing market, protects
Wet moisturizing effect is poor, and chemical addition agent is more in toner, and irreversible influence is easily caused on skin, hinders Skin Cell
Metabolism damages Skin Cell, causes the adverse reactions such as clogging of pores, chloasma, blackspot, fash.
Solve the difficulty and meaning of above-mentioned technical problem：
Most of main component water on existing market in common toner uses distilled water, and water clusters water is by 13-
15 or more hydrone arrangements, molecular diameter are more than 2nm, it is difficult to be absorbed by the skin, moisturizing moisturizing effect is poor, and changes in toner
It is more to learn additive, irreversible influence is easily caused on skin, hinders the metabolism of Skin Cell, damages Skin Cell, makes
Into adverse reactions such as clogging of pores, chloasma, blackspot, fash.
The small-micelle water alcohol-free toner of the present invention is conducive to cutin-softening albumen, makes skin tenderer, smooth, rich
It is flexible, enhance skin resistance, and using rear to preventing chloasma generation, skin aging wrinkle, wrinkled skin has
Certain effect.
Invention content
In view of the problems of the existing technology, the present invention provides a kind of small-micelle water alcohol-free toner and its preparation sides
Method, cosmetics.
The invention is realized in this way a kind of small-micelle water alcohol-free toner, the small-micelle water alcohol-free toner
According to parts by weight by 80 parts -97 parts of small-micelle water, 0.01 part -5 parts of glycerine, 0.01 part -5 parts of D-sorbite, glycyrrhizic acid two
0.05 part -3 parts of first, 0.01 part -1 part of hyaluronic acid, 0.05 part -0.5 part of menthol, 0.05 part -5 parts of beta glucan, peony seeds
0.05 part of -3 parts of composition of 0.05 part -1 part of oil and citric acid.
It is described small another object of the present invention is to provide a kind of preparation method of the small-micelle water alcohol-free toner
The preparation method of micel water alcohol-free toner includes the following steps：
Step 1, by component A：80-97 parts of small-micelle water, 0.05-3 parts of glycyrrhizic acid diformazan, 0.01-1 parts of hyaluronic acid,
0.05-5 parts of beta glucan is stirred；
Step 2, by B component：0.01-5 parts of glycerine, 0.01-5 parts of D-sorbite, 0.05-0.5 parts of menthol, peony seeds
0.05-1 parts oily, heating water bath is stirred；
Step 3 after B component is cooled to room temperature, is added in component A, and stir, and ultrasonic disperse mixes at low temperature,
Obtain component C；
Citric acid is slowly added into component C by step 4, stirring, at low temperature ultrasonic disperse so that toner maintains
In the weakly acidic condition that a pH value is 6-7, small-micelle water alcohol-free toner is obtained.
Further, it is 40-70Hz that the small-micelle water, which is nuclear magnetic resonance half range width values,.
Further, stir speed (S.S.) is 200-3000rpm, mixing time 10-60min in the step 1.
Further, bath temperature is 40-80 DEG C, stir speed (S.S.) 500-2000rpm in the step 2, and mixing time is
10-60min。
Further, the step in you stir speed (S.S.) be 1000-5000rpm, mixing time 30-120min, ultrasonic disperse
Operating temperature is 10-20 DEG C, ultrasonic power 100-3000W, ultrasonic disperse time 30-120min.
Further, in the step 4 stir speed (S.S.) be 200-1000rpm, mixing time 30-60min, ultrasonic disperse work
It is 10-20 DEG C, ultrasonic power 100-3000W to make temperature, ultrasonic disperse time 30-60min.
It is a kind of yellowish-brown by preventing of preparing of the small-micelle water alcohol-free toner another object of the present invention is to provide
The health products that spot generates.
It is old another object of the present invention is to provide a kind of anti-skin prepared by the small-micelle water alcohol-free toner
Change wrinkle cosmetics.
Another object of the present invention is to provide a kind of wrinkled skin prepared by the small-micelle water alcohol-free toner
Cosmetics.
In conclusion advantages of the present invention and good effect are：Using micromolecular water as solvent, hydrone smaller can be more
Added with conducive to absorption of the Skin Cell to moisture, the metabolism of Skin Cell can be effectively facilitated, there is better moisturizing moisturizing
Effect.And the addition moisturizing used and functional addition reagent, it is nontoxic, more mildly, Skin Cell is not damaged, it is and common
Toner is compared, more mildly.
The small-micelle water alcohol-free toner of the present invention is conducive to cutin-softening albumen, makes skin tenderer, smooth, rich
It is flexible, enhance skin resistance, and using rear to preventing chloasma generation, skin aging wrinkle, wrinkled skin has
Certain effect.
Description of the drawings
Fig. 1 is the preparation method flow chart of small-micelle water alcohol-free toner provided in an embodiment of the present invention.
Specific embodiment
In order to make the purpose , technical scheme and advantage of the present invention be clearer, with reference to embodiments, to the present invention
It is further elaborated.It should be appreciated that the specific embodiments described herein are merely illustrative of the present invention, it is not used to
Limit the present invention.
For the present invention using micromolecular water as solvent, hydrone smaller can be more conducive to suction of the Skin Cell to moisture
It receives, the metabolism of Skin Cell can be effectively facilitated, there is better moisturizing moisturizing effect.
Small-micelle water alcohol-free toner provided in an embodiment of the present invention is according to parts by weight by 80 part -97 of small-micelle water
Part, 0.01 part -5 parts of glycerine, 0.01 part -5 parts of D-sorbite, 0.05 part -3 parts of glycyrrhizic acid diformazan, 0.01 part -1 part of hyaluronic acid,
0.05 part of 0.05 part -0.5 part of menthol, 0.05 part -5 parts of beta glucan, 0.05 part -1 part of peony seed oil and citric acid -3 parts of group
Into.
As shown in Figure 1, the preparation method of small-micelle water alcohol-free toner provided in an embodiment of the present invention includes following step
Suddenly：
S101：By component A：80-97 parts of small-micelle water, 0.05-3 parts of glycyrrhizic acid diformazan, 0.01-1 parts of hyaluronic acid, β-
0.05-5 parts of glucan is uniformly mixed；
S102：By B component：0.01-5 parts of glycerine, 0.01-5 parts of D-sorbite, 0.05-0.5 parts of menthol, peony seed oil
0.05-1 parts, heating water bath is uniformly mixed；
S103：It after B component is cooled to room temperature, is slowly added in component A, and stirs, the ultrasound point under certain low temperature
It dissipates and is uniformly mixed, obtain component C；
S104：Finally citric acid is slowly added into component C, is stirred, the ultrasonic disperse under certain low temperature so that skin toner
Water maintains weakly acidic condition of the pH value between 6-7 to get to the small-micelle water alcohol-free toner.
As the preferred embodiment of the present invention, the small-micelle water is that nuclear magnetic resonance half range width values are 40-70Hz；
As the preferred embodiment of the present invention, the small-micelle water can be natural excavation or manually be prepared
's；
As the preferred embodiment of the present invention, the glycerine, D-sorbite, citric acid is food grade, and purity is more than
99%；
As the preferred embodiment of the present invention, the peony seed oil is the high nutrition to be obtained by subcritical biotechnology
Composition peony seed oil；
As the preferred embodiment of the present invention, the step 1：Stir speed (S.S.) is 200-3000rpm, mixing time 10-
60min；
As the preferred embodiment of the present invention, the step 2：Bath temperature is 40-80 DEG C, stir speed (S.S.) 500-
2000rpm, mixing time 10-60min；
As the preferred embodiment of the present invention, the step 3：Stir speed (S.S.) is 1000-5000rpm, mixing time 30-
120min, ultrasonic disperse operating temperature are 10-20 DEG C, ultrasonic power 100-3000W, ultrasonic disperse time 30-120min；
As the preferred embodiment of the present invention, the step 4：Stir speed (S.S.) is 200-1000rpm, mixing time 30-
60min, ultrasonic disperse operating temperature are 10-20 DEG C, ultrasonic power 100-3000W, ultrasonic disperse time 30-60min.
The application principle of the present invention is further described with reference to specific embodiment.
Embodiment 1：
Small-micelle water alcohol-free toner provided in an embodiment of the present invention is according to parts by weight by 95 parts of small-micelle water, sweet
1 part of oil, 0.5 part of D-sorbite, 0.5 part of glycyrrhizic acid diformazan, 0.3 part of hyaluronic acid, 1 part of menthol, 1 part of beta glucan, tree peony
0.4 part of composition of 0.3 part of seed oil and citric acid.
The preparation method of small-micelle water alcohol-free toner provided in an embodiment of the present invention includes the following steps：
(1) by component A：95 parts of small-micelle water, 0.5 part of glycyrrhizic acid diformazan, 0.3 part of hyaluronic acid, 1 part of beta glucan,
It is uniformly mixed, stir speed (S.S.) 500rpm, mixing time 30min；
(2) by B component：1 part of glycerine, 0.5 part of D-sorbite, 1 part of menthol, 0.3 part of peony seed oil, 60 DEG C of water-baths add
Heat is uniformly mixed, stir speed (S.S.) 1000rpm, mixing time 30min；
(3) it after B component being cooled to room temperature, is slowly added in component A, and stirs, stir speed (S.S.) 1000rpm, stirring
Time 60min, ultrasonic disperse is uniformly mixed under 15 DEG C of low temperature, ultrasonic power 300W, ultrasonic time 60min, obtains component C；
(4) finally citric acid is slowly added into component C, stirred, stir speed (S.S.) 600rpm, mixing time 30min,
Ultrasonic disperse under 15 DEG C of low temperature, ultrasonic power 200W, ultrasonic time 30min so that toner maintain a pH value for 6-7 it
Between weakly acidic condition to get to the small-micelle water alcohol-free toner.
Embodiment test analysis：
6 months, 1 year, 1.5 years, 2 years, 3 years five each 10 of time limit rabbits of raising are chosen, it is symmetrically left at rabbit back
The skin test region of 2*2cm is respectively picked out in right both sides, and each age bracket of feeding respectively selects 5 implementation in right side spraying 0.5g real
The micromolecular water toner skin care item of example 1, each certain brand fed the remaining 5 right sides spraying 0.5g of age bracket and bought in the market
Toner, every 24 hours, each spraying was primary, continuous spray 7 days, observed the response situation of the right skin area of rabbit.
Specific test case is listed as follows：
Rabbit tests 7 days skin conditions
| Serial number | Feeding time | Embodiment 1 | Market brand toner | Remarks |
| 1 | 6 months | Without ill symptoms | Without ill symptoms | |
| 2 | 1 year | Without ill symptoms | Without ill symptoms | |
| 3 | 1.5 year | Without ill symptoms | 3 mild rash | |
| 4 | 2 years | Without ill symptoms | 5 mild rash | |
| 5 | 3 years | Without ill symptoms | It is 6 fash, rubescent |
It is demonstrated experimentally that the small-micelle water alcohol-free toner using embodiment 1 is milder to skin, it is safer.
Volunteer's test efficacy situation
120,20-30,30-40,40-50,50-60 are selected, each 30 of the volunteer of this 4 age bracket, each age bracket is every
10 one group of statuses are divided into 3 groups, and one of which volunteer uses 1 sample of embodiment, and another set volunteer uses market product
Board skin toner aquatic products, last group are compared using distilled water.
Effect situation is described as follows：
It is obviously improved：Skin is fine and smooth, and more smooth, moistening effect is good
There is improvement：Moistening effect is general, and skin exquisiteness is a bit
Effect is general：Skin essentially unchangedization
Aging wrinkle is reduced：Skin is finer and smoother, aging wrinkle spread apart, and wrinkle quantity is reduced
Chloasma is reduced：The original chloasma quantity of skin is reduced, and skin is finer and smoother
Volunteer's test uses comparison situation table after one month
Volunteer's test experiments prove, skin can be allowed finer and smoother using this small-micelle water alcohol-free toner, moisturizing
Effect is more preferable, can effectively reduce aging wrinkle and chloasma.
The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all essences in the present invention
All any modification, equivalent and improvement made within refreshing and principle etc., should all be included in the protection scope of the present invention.
Claims (10)
1. a kind of small-micelle water alcohol-free toner, which is characterized in that the small-micelle water alcohol-free toner is according to parts by weight
Number is by 80 parts -97 parts of small-micelle water, 0.01 part -5 parts of glycerine, 0.01 part -5 parts of D-sorbite, 0.05 part -3 of glycyrrhizic acid diformazan
Part, 0.01 part -1 part of hyaluronic acid, 0.05 part -0.5 part of menthol, 0.05 part -5 parts of beta glucan, 0.05 part -1 of peony seed oil
0.05 part of -3 parts of composition of part and citric acid.
A kind of 2. preparation method of small-micelle water alcohol-free toner as described in claim 1, which is characterized in that the small molecule
The preparation method of group's water alcohol-free toner includes the following steps：
Step 1, by component A：80-97 parts of small-micelle water, 0.05-3 parts of glycyrrhizic acid diformazan, 0.01-1 parts of hyaluronic acid, β-Portugal
0.05-5 parts of glycan is stirred；
Step 2, by B component：0.01-5 parts of glycerine, 0.01-5 parts of D-sorbite, 0.05-0.5 parts of menthol, peony seed oil
0.05-1 parts, heating water bath is stirred；
Step 3 after B component is cooled to room temperature, is added in component A, and stir, and ultrasonic disperse mixes at low temperature, obtains
Component C；
Citric acid is added in component C by step 4, stirring, at low temperature ultrasonic disperse so that toner maintains a pH
It is worth the weakly acidic condition for 6-7, obtains small-micelle water alcohol-free toner.
3. the preparation method of small-micelle water alcohol-free toner as claimed in claim 2, which is characterized in that the subset
Water is that nuclear magnetic resonance half range width values are 40-70Hz.
4. the preparation method of small-micelle water alcohol-free toner as claimed in claim 2, which is characterized in that in the step 1
Stir speed (S.S.) is 200-3000rpm, mixing time 10-60min.
5. the preparation method of small-micelle water alcohol-free toner as claimed in claim 2, which is characterized in that in the step 2
Bath temperature is 40-80 DEG C, stir speed (S.S.) 500-2000rpm, mixing time 10-60min.
6. the preparation method of small-micelle water alcohol-free toner as claimed in claim 2, which is characterized in that the step is in you
Stir speed (S.S.) is 1000-5000rpm, and mixing time 30-120min, ultrasonic disperse operating temperature is 10-20 DEG C, ultrasonic power
100-3000W, ultrasonic disperse time 30-120min.
7. the preparation method of small-micelle water alcohol-free toner as claimed in claim 2, which is characterized in that in the step 4
Stir speed (S.S.) is 200-1000rpm, and mixing time 30-60min, ultrasonic disperse operating temperature is 10-20 DEG C, ultrasonic power 100-
3000W, ultrasonic disperse time 30-60min.
8. prepared by a kind of small-micelle water alcohol-free toner as described in claim 1 prevents the health products that chloasma generates.
9. a kind of resisting age of skin wrinkle cosmetics prepared by small-micelle water alcohol-free toner as described in claim 1.
10. a kind of cosmetics of wrinkled skin prepared by small-micelle water alcohol-free toner as described in claim 1.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201810223541.9A CN108186376A (en) | 2018-03-19 | 2018-03-19 | A kind of small-micelle water alcohol-free toner and preparation method thereof, cosmetics |
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| CN201810223541.9A CN108186376A (en) | 2018-03-19 | 2018-03-19 | A kind of small-micelle water alcohol-free toner and preparation method thereof, cosmetics |
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| CN110755274A (en) * | 2018-07-26 | 2020-02-07 | 佐见啦生技股份有限公司 | Skin care composition and method for producing the same |
| CN111658554A (en) * | 2019-11-19 | 2020-09-15 | 深圳市婵小君化妆品有限公司 | Cosmetic based on small molecular group water and preparation method thereof |
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| CN110755274A (en) * | 2018-07-26 | 2020-02-07 | 佐见啦生技股份有限公司 | Skin care composition and method for producing the same |
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