CN108144660A - For accommodating the sample container of small volumes of liquids sample - Google Patents
For accommodating the sample container of small volumes of liquids sample Download PDFInfo
- Publication number
- CN108144660A CN108144660A CN201711269377.7A CN201711269377A CN108144660A CN 108144660 A CN108144660 A CN 108144660A CN 201711269377 A CN201711269377 A CN 201711269377A CN 108144660 A CN108144660 A CN 108144660A
- Authority
- CN
- China
- Prior art keywords
- sample
- housing region
- sample container
- cone
- outflow opening
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/02—Devices for withdrawing samples
- G01N1/10—Devices for withdrawing samples in the liquid or fluent state
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/34—Purifying; Cleaning
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/38—Diluting, dispersing or mixing samples
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/40—Concentrating samples
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/40—Concentrating samples
- G01N1/4022—Concentrating samples by thermal techniques; Phase changes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/06—Fluid handling related problems
- B01L2200/0689—Sealing
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/14—Process control and prevention of errors
- B01L2200/141—Preventing contamination, tampering
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/04—Closures and closing means
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/04—Closures and closing means
- B01L2300/041—Connecting closures to device or container
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/04—Closures and closing means
- B01L2300/046—Function or devices integrated in the closure
- B01L2300/049—Valves integrated in closure
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/06—Auxiliary integrated devices, integrated components
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0848—Specific forms of parts of containers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/56—Labware specially adapted for transferring fluids
- B01L3/567—Valves, taps or stop-cocks
Abstract
The present invention relates to a kind of for accommodating the sample container of small volumes of liquids sample, the sample that the sample is obtained preferably through gas-phase decomposition, the wherein container have the housing region being open upwards.According to the present invention, which has outflow opening at its minimum point, which is reversibly closed in fluid-tight manner by the actuator with confining surface.
Description
Technical field
The present invention relates to a kind of sample container for accommodating small volumes of liquids sample and use the sample container
Method.
Background technology
Sample container for accommodating small volumes of liquids sample is used for various technologies and scientific domain.For example, analyzing
In the sample preparation methods of chemistry, the fluid sample obtained before actual analysis is stored in sample container, such as with
In further conditioning (dilution), prepare to measure.
In the context of the prior art, usually using so-called small in shelf (that is, bracket for lot cargo)
Bottle, these shelf remove from application places and are changed to NEW PRODUCTS (or clean shelf) after usage.This intervention is arranged
It is labor-intensive to apply, and with very high pollution risk.
Invention content
The object of the present invention is to provide a kind of sample container, which can remain fixed using place, and
It need not remove or replace after use.Another object of the present invention includes proposing the suitable method using this sample container.
In this context, the present invention relates to a kind of for accommodating the sample container of small volumes of liquids sample, the sample is excellent
Choosing is by the sample that obtains of being decomposed by gas phase, and the wherein container has the housing region that is open upwards, the housing region at it most
There is exit opening, which is reversibly closed in fluid-tight manner by the actuator with confining surface at low spot.
In one embodiment, housing region is taper, and the minimum point of housing region is formed by the vertex of a cone.According to this
The understanding of invention, the housing region with bending directrix are also considered as taper.However, it is preferred to the circular cone with straight directrix
Body.Straight or oblique cone is typically what is be envisioned that.The subtended angle of cone can preferably exist for example between 60 ° and 100 °
Between 70 ° and 90 °.
In one embodiment, exit opening starts from the vertex of a cone and is only extended in one direction to cone since the vertex of a cone
In surface.This does not generate asymmetrical design of the exit opening relative to cone, the wherein vertex of a cone not at the center of exit opening or not
In exit opening, but the edge of exit opening extends directly through the vertex of a cone.
Exit opening may, for example, be round or ellipse.
In one embodiment, the confining surface of actuator follows the profile of housing region.The jacket surface of housing region
Therefore there is no scrambling in the case where exit opening is closed.
In one embodiment, actuator is plunger, can be preferably moved parallel to the axis of cone, with from cone
The surface range of body reversibly pulls downwards confining surface and therefore reversibly discharges exhaust openings.Plunger may, for example, be gas
Dynamic operation.
There may be emission quotas at the opposite side of exhaust openings.Exhaust openings or emission quotas (if present)
Extractor is preferably attached to, and is preferably attached to generate very (if present) in exhaust openings or emission quotas
Empty pump.Therefore in the case where exit opening is opened, liquid can be extracted downwards.
In one embodiment, housing region is surrounded at its open upside by overflow area.Packing station and/or extraction
The upside of sample container can be arranged in by standing, and can pipette tip be directed to housing region.
Housing region can be manufactured or can be coated with fluoroplastics by fluoroplastics.Suitable fluoroplastics for example comprising
PTFE/PPVE copolymers.This is equally applicable to actuator or at least its confining surface and overflow area and discharge areas or row
Between emptying.Fluoroplastics usually have significant chemical resistance and hydrophobicity and oleophobic property.But it is also possible to it provides, for example, causing
It moves device and optionally its confining surface can be manufactured by PEEK.Different material, stainless steel, ceramics etc. can also be used
In specific application region.
Relative to the background that beginning proposes, the invention further relates to a kind of sides using sample container according to the present invention
Method, wherein after sample is removed and during the idle phase before being filled with new sample, housing region is filled with replacement liquid
Body.
It provides in one embodiment, the housing region of sample container is covered during idle phase.
It provides, drops to after a predetermined time period has elapsed and/or during idle phase predetermined in one embodiment
After under liquid level, additional replacement liquid is filled it up in housing region.
Outflow opening can remain turned-off during idle phase.
Substituting liquid can be for example corresponding to the optional diluted carrier fluid of sample.If carrier fluid is, for example, acid, such as in gas phase
Situation in decomposition is such, then can specify that the acid concentration in flushing liquid is lower than the acid concentration in carrier fluid.Show in an application
In example, it is diluted hydrofluoric acid to substitute liquid.
Relative to the background that beginning proposes, the invention further relates to a kind of method using sample container according to the present invention,
Wherein, it after sample is removed, runs at least one flush cycle and preferably runs multiple flush cycles, wherein housing region is used
Flushing liquid rinses, and in each flush cycle in the case where outflow opening is closed, is filled at least partly with flushing liquid
Then outflow opening is opened to discharge flushing liquid in housing region.However, in the case where outflow opening is opened, can also lead to
It crosses emission quotas and enters overflow area to carry out back flush.
It can optionally provide, in the case where outflow opening is opened, flushing liquid is initiatively extracted out.
Multiple flush cycle can be advantageous, because cleaning performance can wash away wall repeatedly by using phase boundary to realize.
Armed with multiple flush cycles, then the different fillings of housing region can be provided for different flush cycles
Amount.In last flush cycle, such as housing region can be filled into overflow.Allow to remove in this way and be attached to receiving
Drop on the wall in region.
Flushing liquid for example can be water or another solvent that can form carrier fluid matrix.
In one embodiment, after sample is removed and outflow opening close in the case of run flush cycle it
Before, housing region is filled at least partly with cleaning fluid, and outflow opening is opened after by Clean after every to discharge cleaning
Liquid.
The step is present in any sample residues in housing region for dissolving.
Cleaning liquid for example can correspond to the carrier fluid of sample.In an application example, cleaning liquid can be concentration
Hydrofluoric acid.
Relative to the background being initially mentioned, the invention further relates to a kind of method using sample container according to the present invention,
Wherein, it in the front opening outflow opening for filling a sample into housing region, until flushing liquid or substitutes liquid and flows completely out, and
And it is introduced into housing region wherein to outflow opening applying vacuum during the opening and/or by flushing gas.
So that the noresidue outflow of flushing liquid or replacement liquid is possibly realized.
In one embodiment it can be stated that in the case of empty housing region, in flushing liquid or liquid flow is substituted
Go out and then it is secondary closing and opening outflow opening at least once, wherein vacuum may be applied to outflow opening and/or rinse gas
Body is introduced in during repeating to open in housing region.
Therefore any liquid residue being present in the gap area between confining surface and jacket surface can be moved
Except without residue.
Two or more methods according to the present invention in combination with one another can handle the normal of small volumes of liquids sample to be formed
Square method.
In one embodiment, a part for the method for sample analysis is formed according to the method for the present invention, wherein with
Fluid sample is added in the analytical equipment of such as mass spectrograph or gas chromatographic column afterwards.It is for example wrapped for the method for sample analysis
Gas-phase decomposition is included, is preferred for pollutant being concentrated on the substrate of such as silicon substrate.
However, different sample preparation methods can also utilize the present invention to include buffering liquid wherein for preparing
And/or implement in the different sections of processing/operation.
Description of the drawings
The other details and advantage of the present invention are generated from the following embodiment being described with reference to the drawings.In the drawings：
Fig. 1 is the perspective view of sample container according to the present invention；
Fig. 2 is the side view according to the sample container of Fig. 1；
Fig. 3 is the top view according to the sample container of Fig. 1；
Fig. 4 is the sectional view according to the sample container of Fig. 1；And
Fig. 5 is the schematic diagram of multiple method and steps that can be performed at sample container according to the present invention.
Specific embodiment
Fig. 1 to Fig. 4 shows the embodiment of sample container according to the present invention, is usually marked by reference numeral 1.
Container 1 has the housing region 2 being open upwards.Housing region 2 has the form of right circuit cone, has straight
Directrix, 80 ° of subtended angle, and minimum point is formed by the vertex of a cone 3.
Housing region 2 has the outflow opening 4 of ellipse at its minimum point, which can pass through plunger 6
Confining surface 5 is closed with reversible fluid tight manner.Plunger 6 can move downward with the surface range from cone along the axis of cone
It reversibly pulls confining surface 5 and reversibly discharges exhaust openings 4.It is pneumatically-operated.
The confining surface 5 of plunger 6 follows the profile of cone surface so that in the case where closing outflow opening 4, cone table
Face does not have scrambling.The surface that outflow opening 4 starts from the vertex of a cone 3 and only extended in one direction since the vertex of a cone 3 to cone
In.This generates asymmetrical design of the exit opening 4 relative to cone, and the vertex of a cone 3 not at the center of exit opening 4 or is going out
In mouth opening 4, but the edge of exit opening 4 extends directly through the vertex of a cone 3.
Cone 2 is accommodated to be located at the central axis of sample container 1, and plunger 6 and opening 4 are relative in sample container 1
Mandrel line skew.Therefore opening 4 is realized relative to the asymmetric position of the vertex of a cone 3 by the offset of plunger 6.
There are emission quotas 7 at the opposite side of exhaust openings 4, and the emission quotas 7 is via connector 14 and suction line
Connection, so as to generate vacuum at exhaust openings 4 and in emission quotas 7.
Housing region 2 at open upside by annular run-off 9 circumferentially around.
It filling with multiple containers 12 and removes station 11 and is further placed in the web (web) 10 of sample container (it is with ring
Shape mode surrounds run-off 9) on, to keep the discharge nozzle 13 for drop separation (drop separation), discharge spray
Mouth 13 is projected into housing region 2 or leads to housing region 2.
All fluid contact components are all made of PTFE/PPVE copolymers.Pneumatic actuator 15 shown in Fig. 4 by
PEEK is made, and is supported for preventing from rotating in associated cylinder in a position-stable manner.
Therefore shown sample container 1 can be used for for example accommodating sample, accommodate sample in gas-phase decomposition process (VPD)
Preparation and scanning process after occur.Sample can be diluted in cone 2 is accommodated and be provided to corresponding measurement dress
It puts (for example, ICP-MS).It can substitute the bottle shelf commonly used in this purpose, but remain fixed in the machine, and
And need not replace, thus avoid personnel's intervention.Eliminate complicated and responsible of exterior washings bottle and its transport
Business.Further pollution risk is minimized.These targets be by specifically designing, the confession of used material, respective media
Should and related process method realize.According to the model of fixed supply container, fixed sample container can be each
It is cleaned after use, and can effectively be dried before next use in the machine.Additionally it is suitable for very small
Volume, such as volume needed for VPD samples.
The advantages of equipment according to the present invention, is, it is not necessary to which device for opening is to be inserted into bottle.Therefore there is no pollutant can be with
It penetrates into the housing of encapsulation.Therefore, the detectable limit of pollutant etc. is very low.Due to the system, exist and can be described as can be used
In endless supply of the bottle of analysis.Identical cleaning procedure can be always performed, thus it is necessary in analysis precision
The fluctuation of receiving is less.The equipment especially suitable for testing and remote testing for a long time.
For example, when using sample container 1 according to the present invention, following (part) process can be used.
Idle phase：
About first group of process, under standby mode (basic status or idle phase), accommodate cone 2 and be closed and fill out
Filled with diluted VPD solution (for example, diluted hydrofluoric acid).(6 hours or system are being greater than with the longer stand-by period
Stop) in the case of, independent process, which also provides, to be filled it up with to compensate evaporation.Therefore it prevents from being dried, and table is carried out with VPD matrix
Face improves (matrix constancy).
Before measuring：
Once carry out sample measurement or blank measure, accommodate cone 2 be just drained and without ultra-pure water (UPW) rinse with
Matrix is avoided to change.Residual drop in the region of outflow opening 4 is inhaled by being applied to the vacuum on connector 17
Into space 7.Then, plunger 6 moves again up, and will likely be still present in opening 4 edge and confining surface 5 it
Between gap area in very small amount of liquid (magnitude of 1 μ l) be pressed in opening 4 edge on.These liquid second and
Last time is opened and is aspirated in cycle and is removed.These processes are assisted in housing region 2 by the way that nitrogen is blown into.It accommodates
Region 2 is now drying and is ready for sample receiving.
After the measurement：
After measurement process, cleaning and initial filling are carried out (after the measurement) to improve with diluted VPD solution
And protect the wall of housing region 2.Therefore, sample container 1 is again at basic status.This process usually should intervene and
It carries out entering basic status after unknown state.When the partial routine starts, by the VPD solution concentrated on a small quantity (such as 1%
Hydrofluoric acid) be injected into the lower area for accommodating cone 2 to reach low pH.Therefore, it should prevent from being dissolved in residue
The precipitation of pollutant, and it should be ensured that the better dissolving of sample solution residue.Now above emission direction and from overflow
It flows and multiple UPW flush cycles is carried out below direction.The alternating of plunger opens and closes phase boundary offer of the period by liquid to holding
The wall in region 2 received washes away repeatedly.Which increase the validity of cleaning.Finally, by housing region 2 be filled into run-off 9 and
It empties to remove the residual droplets being attached on wall.In the final step, it is filled with diluted VPD solution.Dilution be through
It is set by water inflow using time control, therefore not fully corresponds to and measure matrix.This requirement is not at this moment must
It wants, and is abandoned to support to save total processing time expensive matrix components simultaneously.
It prevents from being dried and protect：
Further (part) process can be used together to prevent from being dried with time control.If being not carried out filling it up with
It is more than special time period in the case of processing, then this process is begun to.If prepare measure program finally perform and
If housing region 2 is dry, exception rule comes into force.If (such as 1 hour) does not occur clearly within the time that can be set
It washes, then assumes that system has stopped.In order to which protective bulkhead is from pollution, force to be filled housing region 2 and sample container 1
It is again at basic status (idle phase).Here it is also applied for abandoning matrix constancy to support total processing time.
Establish calibration standard：
In order to establish calibration standard, (such as before measuring) matrix can be measured with (accurate) after cleaning procedure
Cone 2 will be accommodated to fill it up with.This is accurately carried out relative to concentration.
Processing routine can be identified schematically in Figure 5.
The state of sample container 1 is marked usually in figure with reference numeral 100.Reference numeral 101 represents standby mode,
The middle cone 2 that accommodates is filled with matrix consistent diluted VPD solution or sample；Reference numeral 102 represents have in housing region 2
There is the state of sample；And reference numeral 103 represents the idle state not used after multiple hours.
(part) processing entirety by reference number 200 represents.Reference numeral 201 represents " measured according to foregoing description
Preparation process before ".Reference numeral 202 represents the cleaning step according to foregoing description " after the measurement ".Reference numeral 203
Represent the routine according to foregoing description " preventing from being dried protecting ".
Claims (10)
1. a kind of sample container for being used to accommodate small volumes of liquids sample, the sample that the sample is obtained preferably through gas-phase decomposition
Product, wherein the container has the housing region being open upwards,
It is characterized in that,
The housing region at its minimum point have outflow opening, the outflow opening by the actuator with confining surface with
Fluid tight manner is reversibly closed.
2. sample container according to claim 1, which is characterized in that the housing region is taper, and the appearance
The minimum point in region received is formed by the vertex of a cone.
3. sample container according to claim 2, which is characterized in that the outflow opening starts from the vertex of a cone and from institute
It states in the surface that the vertex of a cone starts only to extend in one direction cone.
4. sample container according to any one of the preceding claims, which is characterized in that the confining surface of the actuator
Follow the profile of the housing region.
5. sample container according to any one of the preceding claims, which is characterized in that the actuator is plunger, described
Plunger can be moved preferably along the axis of cone, reversibly to pull the confining surface from the surface range of the cone,
Therefore exhaust openings are reversibly discharged.
6. sample container according to any one of the preceding claims, which is characterized in that the housing region is opened wide at it
Upside at surrounded by overflow area.
7. a kind of method using sample container according to any one of the preceding claims,
It is characterized in that,
After sample is removed and during the idle phase before being filled with new sample, the receiving area is filled with liquid is substituted
Domain.
8. a kind of method of sample container of use according to any one of claim 1-6,
It is characterized in that,
At least one flush cycle is run after sample is removed and preferably runs multiple flush cycles, wherein being rushed with flushing liquid
The housing region is washed, in each flush cycle in the case where closing outflow opening, is filled out at least partly with flushing liquid
The housing region is filled, then opens outflow opening to discharge the flushing liquid.
9. according to the method described in claim 8, it is characterized in that, after the sample is removed and in outflow opening closing
In the case of run the flush cycle before, the housing region is filled at least partly with cleaning liquid, through between over cleaning
Every opening the outflow opening later to discharge the cleaning liquid.
10. a kind of method of sample container of use according to any one of claim 1-6,
It is characterized in that,
Before the housing region is filled with sample, the outflow opening is opened until flushing liquid or replacement liquid are complete
Outflow, and apply vacuum to the outflow opening in opening procedure and/or flushing gas is introduced into the housing region
In.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE102016014457.2 | 2016-12-05 | ||
| DE102016014457.2A DE102016014457A1 (en) | 2016-12-05 | 2016-12-05 | Sample vessel for receiving small-volume liquid samples |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN108144660A true CN108144660A (en) | 2018-06-12 |
| CN108144660B CN108144660B (en) | 2022-02-22 |
Family
ID=60543314
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201711269377.7A Active CN108144660B (en) | 2016-12-05 | 2017-12-05 | Sample container for containing small volume liquid sample |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US10618048B2 (en) |
| EP (1) | EP3329993B1 (en) |
| JP (1) | JP7079084B2 (en) |
| CN (1) | CN108144660B (en) |
| DE (1) | DE102016014457A1 (en) |
| TW (1) | TWI766909B (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2021051688A1 (en) * | 2019-09-19 | 2021-03-25 | 陈俊林 | Micro-reagent mixing and adding device |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA3033195A1 (en) * | 2018-02-09 | 2019-08-09 | Ecolab Usa Inc. | Flowability testing systems and methods |
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- 2017-12-05 JP JP2017233048A patent/JP7079084B2/en active Active
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Also Published As
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| KR20180064320A (en) | 2018-06-14 |
| US20180154352A1 (en) | 2018-06-07 |
| EP3329993A1 (en) | 2018-06-06 |
| EP3329993B1 (en) | 2020-01-08 |
| TW201827831A (en) | 2018-08-01 |
| JP2018091851A (en) | 2018-06-14 |
| TWI766909B (en) | 2022-06-11 |
| JP7079084B2 (en) | 2022-06-01 |
| CN108144660B (en) | 2022-02-22 |
| DE102016014457A1 (en) | 2018-06-07 |
| US10618048B2 (en) | 2020-04-14 |
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