CN108136123A - 带有配量装置的自动注射器具 - Google Patents
带有配量装置的自动注射器具 Download PDFInfo
- Publication number
- CN108136123A CN108136123A CN201680056944.8A CN201680056944A CN108136123A CN 108136123 A CN108136123 A CN 108136123A CN 201680056944 A CN201680056944 A CN 201680056944A CN 108136123 A CN108136123 A CN 108136123A
- Authority
- CN
- China
- Prior art keywords
- syringe
- metering unit
- housing
- injection
- situation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000007924 injection Substances 0.000 title claims abstract description 101
- 238000002347 injection Methods 0.000 title claims abstract description 101
- 239000012530 fluid Substances 0.000 claims abstract description 33
- 239000007788 liquid Substances 0.000 claims abstract description 16
- 238000001125 extrusion Methods 0.000 claims abstract description 7
- 230000002093 peripheral effect Effects 0.000 claims description 11
- 230000006835 compression Effects 0.000 claims description 10
- 238000007906 compression Methods 0.000 claims description 10
- 238000010276 construction Methods 0.000 claims description 8
- 239000004744 fabric Substances 0.000 claims description 3
- 230000000149 penetrating effect Effects 0.000 claims 1
- 230000000694 effects Effects 0.000 description 5
- 208000005189 Embolism Diseases 0.000 description 4
- 238000010586 diagram Methods 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- 229920001971 elastomer Polymers 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 239000003182 parenteral nutrition solution Substances 0.000 description 2
- 239000000806 elastomer Substances 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 239000012780 transparent material Substances 0.000 description 1
- 239000013585 weight reducing agent Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31545—Setting modes for dosing
- A61M5/31548—Mechanically operated dose setting member
- A61M5/3155—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe
- A61M5/31551—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe including axial movement of dose setting member
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31545—Setting modes for dosing
- A61M5/31548—Mechanically operated dose setting member
- A61M5/3155—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe
- A61M5/31553—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe without axial movement of dose setting member
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
- A61M5/31578—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod
- A61M5/3158—Constructional features or modes of drive mechanisms for piston rods based on axial translation, i.e. components directly operatively associated and axially moved with plunger rod performed by axially moving actuator operated by user, e.g. an injection button
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
- A61M5/31583—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod
- A61M5/31585—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod performed by axially moving actuator, e.g. an injection button
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
- A61M2005/2026—Semi-automatic, e.g. user activated piston is assisted by additional source of energy
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
- A61M2005/2403—Ampoule inserted into the ampoule holder
- A61M2005/2407—Ampoule inserted into the ampoule holder from the rear
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M2005/3125—Details specific display means, e.g. to indicate dose setting
- A61M2005/3126—Specific display means related to dosing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
- A61M2205/581—Means for facilitating use, e.g. by people with impaired vision by audible feedback
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31501—Means for blocking or restricting the movement of the rod or piston
- A61M5/31505—Integral with the syringe barrel, i.e. connected to the barrel so as to make up a single complete piece or unit
Landscapes
- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Abstract
Description
Claims (13)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE202015006845.6U DE202015006845U1 (de) | 2015-09-30 | 2015-09-30 | Injektionsgerät |
DE202015006845.6 | 2015-09-30 | ||
PCT/EP2016/001597 WO2017054914A1 (de) | 2015-09-30 | 2016-09-26 | Autoinjektor mit dosiervorrichtung |
Publications (2)
Publication Number | Publication Date |
---|---|
CN108136123A true CN108136123A (zh) | 2018-06-08 |
CN108136123B CN108136123B (zh) | 2021-06-29 |
Family
ID=55274245
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201680056944.8A Active CN108136123B (zh) | 2015-09-30 | 2016-09-26 | 带有配量装置的自动注射器具 |
Country Status (9)
Country | Link |
---|---|
US (1) | US10751475B2 (zh) |
EP (1) | EP3355965B1 (zh) |
JP (1) | JP6718959B2 (zh) |
CN (1) | CN108136123B (zh) |
CA (1) | CA3000278A1 (zh) |
DE (1) | DE202015006845U1 (zh) |
HK (1) | HK1251967A1 (zh) |
RU (1) | RU2688806C1 (zh) |
WO (1) | WO2017054914A1 (zh) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE202015006842U1 (de) | 2015-09-30 | 2016-01-15 | Haselmeier Ag | Injektionsgerät |
DE202015006841U1 (de) | 2015-09-30 | 2016-01-15 | Haselmeier Ag | Injektionsgerät |
PL227678B1 (pl) * | 2015-12-22 | 2018-01-31 | Copernicus Spolka Z Ograniczona Odpowiedzialnoscia | Układ sterująco-napędowy dla urządzenia do iniekcji oraz urządzenie do iniekcji zaopatrzone w taki układ |
EP3108914B1 (en) * | 2016-07-07 | 2019-02-27 | Copernicus SP. Z O.O. | Injection device for delivering a defined number of equal doses of a liquid substance |
US11547806B2 (en) * | 2016-09-09 | 2023-01-10 | Sanofi-Aventis Deutschland Gmbh | Data collection apparatus for attachment to an injection device |
EP3694584A1 (en) * | 2017-10-10 | 2020-08-19 | Novo Nordisk A/S | Prefilled drug delivery device with reduced air gap |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101370540A (zh) * | 2005-12-20 | 2009-02-18 | 特克法马许可公司 | 带有轴向重叠布置的计量或者指示元件的注射装置 |
US20120101452A1 (en) * | 2009-03-31 | 2012-04-26 | Sanofi-Aventis Deutschland Gmbh | Drug delivery device |
CN104220117A (zh) * | 2012-02-10 | 2014-12-17 | 海斯迈有限责任公司 | 注射器 |
CN104321096A (zh) * | 2012-03-30 | 2015-01-28 | 特克法马许可公司 | 带有剂量显示器和弹簧驱动器的注射装置 |
WO2015117746A1 (de) * | 2014-02-05 | 2015-08-13 | Haselmeier Gmbh | Injektionsgerät |
Family Cites Families (25)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3638984C3 (de) * | 1986-11-14 | 1993-11-18 | Haselmeier Wilhelm Fa | Injektionsgerät |
DK166948B1 (da) | 1988-02-10 | 1993-08-09 | Dcp Af 1988 As | Doseringsenhed til dosering af et antal afmaalte maengder af en vaeske, saasom insulin, fra en glastubule |
DK0525525T3 (da) | 1991-07-24 | 1995-10-02 | Medico Dev Investment Co | Injektor |
US6221053B1 (en) | 1998-02-20 | 2001-04-24 | Becton, Dickinson And Company | Multi-featured medication delivery pen |
CN1268405C (zh) * | 2000-10-09 | 2006-08-09 | 伊莱利利公司 | 用于甲状旁腺激素给药的笔式装置 |
GB0304822D0 (en) * | 2003-03-03 | 2003-04-09 | Dca Internat Ltd | Improvements in and relating to a pen-type injector |
GB0306642D0 (en) * | 2003-03-22 | 2003-04-30 | Dca Design Int Ltd | Improvements in and relating to an injector for a medical product |
DE102007013836A1 (de) | 2007-03-22 | 2008-09-25 | Tecpharma Licensing Ag | Injektionsvorrichtung mit gesteuertem Nadelrückzug |
RU2468829C2 (ru) | 2007-03-23 | 2012-12-10 | Ново Нордиск А/С | Инъекционное устройство, содержащее стопорную гайку |
DE102007026083A1 (de) * | 2007-05-25 | 2008-11-27 | Haselmeier S.A.R.L. | Injektionsgerät |
CH699071A2 (fr) | 2008-07-02 | 2010-01-15 | Flakes S A | Dispositif de freinage et/ou de blocage mécanique. |
GB201015799D0 (en) | 2010-09-21 | 2010-10-27 | Owen Mumford Ltd | Autoinjectors |
DE202013001350U1 (de) | 2013-02-08 | 2014-05-09 | Haselmeier Gmbh | Injektionsgerät |
EP2983750B1 (en) | 2013-04-10 | 2018-08-29 | Sanofi | Dispensing speed control mechanism and injection device |
AR095807A1 (es) | 2013-04-10 | 2015-11-11 | Sanofi Sa | Mecanismo de control de velocidad de dispensación y dispositivo de inyección |
CN105102018B (zh) | 2013-04-10 | 2019-07-05 | 赛诺菲 | 药物输送装置的驱动机构 |
CN105377333A (zh) * | 2013-07-17 | 2016-03-02 | 赛诺菲 | 指示组件 |
CN105392512B (zh) * | 2013-07-17 | 2019-12-03 | 赛诺菲 | 用于药物输送装置的组件及其操作方法 |
US20160317749A1 (en) | 2013-12-20 | 2016-11-03 | Sanofi-Aventis Deutschland Gmbh | Assembly for a drug delivery device and drug delivery device |
DE202014001135U1 (de) | 2014-02-05 | 2015-05-06 | Haselmeier Gmbh | Injektionsgerät |
DE202014001136U1 (de) | 2014-02-05 | 2015-05-06 | Haselmeier Gmbh | Injektionsgerät |
TW201618823A (zh) | 2014-10-09 | 2016-06-01 | 賽諾菲公司 | 藥物傳輸裝置 |
DE202015006841U1 (de) | 2015-09-30 | 2016-01-15 | Haselmeier Ag | Injektionsgerät |
DE202015006844U1 (de) | 2015-09-30 | 2016-01-15 | Haselmeier Ag | Injektionsgerät |
DE202015006842U1 (de) | 2015-09-30 | 2016-01-15 | Haselmeier Ag | Injektionsgerät |
-
2015
- 2015-09-30 DE DE202015006845.6U patent/DE202015006845U1/de active Active
-
2016
- 2016-09-26 JP JP2018516755A patent/JP6718959B2/ja active Active
- 2016-09-26 CA CA3000278A patent/CA3000278A1/en not_active Abandoned
- 2016-09-26 RU RU2018109106A patent/RU2688806C1/ru not_active IP Right Cessation
- 2016-09-26 CN CN201680056944.8A patent/CN108136123B/zh active Active
- 2016-09-26 WO PCT/EP2016/001597 patent/WO2017054914A1/de active Application Filing
- 2016-09-26 EP EP16774452.3A patent/EP3355965B1/de active Active
-
2018
- 2018-03-30 US US15/942,295 patent/US10751475B2/en active Active
- 2018-09-04 HK HK18111284.2A patent/HK1251967A1/zh unknown
Patent Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101370540A (zh) * | 2005-12-20 | 2009-02-18 | 特克法马许可公司 | 带有轴向重叠布置的计量或者指示元件的注射装置 |
US20120101452A1 (en) * | 2009-03-31 | 2012-04-26 | Sanofi-Aventis Deutschland Gmbh | Drug delivery device |
CN104220117A (zh) * | 2012-02-10 | 2014-12-17 | 海斯迈有限责任公司 | 注射器 |
CN104321096A (zh) * | 2012-03-30 | 2015-01-28 | 特克法马许可公司 | 带有剂量显示器和弹簧驱动器的注射装置 |
WO2015117746A1 (de) * | 2014-02-05 | 2015-08-13 | Haselmeier Gmbh | Injektionsgerät |
Also Published As
Publication number | Publication date |
---|---|
JP2018529464A (ja) | 2018-10-11 |
EP3355965A1 (de) | 2018-08-08 |
CN108136123B (zh) | 2021-06-29 |
US10751475B2 (en) | 2020-08-25 |
US20180221587A1 (en) | 2018-08-09 |
DE202015006845U1 (de) | 2016-01-15 |
RU2688806C1 (ru) | 2019-05-22 |
JP6718959B2 (ja) | 2020-07-08 |
CA3000278A1 (en) | 2017-04-06 |
EP3355965B1 (de) | 2021-06-23 |
WO2017054914A1 (de) | 2017-04-06 |
HK1251967A1 (zh) | 2019-05-10 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN108136123A (zh) | 带有配量装置的自动注射器具 | |
CA2294638C (en) | Dose setting device | |
CN105879159B (zh) | 一种可重复使用的注射器及其工作方法 | |
DE3340511C1 (de) | Einmalspritze fuer Druckinfusionsapparate | |
CN106110443A (zh) | 一种注射器 | |
CN115400290B (zh) | 一种胰岛素注射装置 | |
CN107308523A (zh) | 微调注射笔 | |
CN112569431A (zh) | 一种剂量外显的安全无针注射器 | |
CN114099854A (zh) | 一种内分泌糖尿病胰岛素输送设备 | |
CN108290002B (zh) | 注射器 | |
CN211658954U (zh) | 一种新型胰岛素注射笔针头 | |
CN109984826A (zh) | 一种新型穿刺针 | |
CN106267475A (zh) | 一次性可调注射器 | |
CN206120870U (zh) | 一种注射器 | |
CN215273193U (zh) | 一种腰椎穿刺针 | |
CN211433028U (zh) | 一种肿瘤用无创取样装置 | |
CN209108305U (zh) | 一种定量注射器 | |
CN208688873U (zh) | 一种用于糖类检测的样液提取装置 | |
CN207101291U (zh) | 一种自动笔式皮试器 | |
CN110269980B (zh) | 一种麻醉科用持续注射麻醉器 | |
CN107518958B (zh) | 畜禽定量取药喂药器 | |
CN113304356A (zh) | 一种干细胞外泌体的制剂定点穿刺给药器及给药方法 | |
CN205698744U (zh) | 一种可重复使用的注射器 | |
CN206372353U (zh) | 一种一次性可调注射器 | |
CN207821824U (zh) | 采血笔 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
REG | Reference to a national code |
Ref country code: HK Ref legal event code: DE Ref document number: 1251967 Country of ref document: HK |
|
GR01 | Patent grant | ||
GR01 | Patent grant | ||
TR01 | Transfer of patent right |
Effective date of registration: 20220119 Address after: Swiss Hargreaves Patentee after: SULZER MIXPAC AG Address before: St Gallen Patentee before: HASELMEIER GmbH |
|
TR01 | Transfer of patent right | ||
CP01 | Change in the name or title of a patent holder |
Address after: Swiss Hargreaves Patentee after: Medmis Switzerland AG Address before: Swiss Hargreaves Patentee before: SULZER MIXPAC AG |
|
CP01 | Change in the name or title of a patent holder |