CN108135933B - 含有活动精子结构域的蛋白质2和癌症 - Google Patents
含有活动精子结构域的蛋白质2和癌症 Download PDFInfo
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- CN108135933B CN108135933B CN201680044577.XA CN201680044577A CN108135933B CN 108135933 B CN108135933 B CN 108135933B CN 201680044577 A CN201680044577 A CN 201680044577A CN 108135933 B CN108135933 B CN 108135933B
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- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
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- A61P35/02—Antineoplastic agents specific for leukemia
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P35/04—Antineoplastic agents specific for metastasis
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- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
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- C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
- C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
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- G01N33/5017—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing toxicity for testing neoplastic activity
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- G01N33/502—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects
- G01N33/5029—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing or evaluating the effect of chemical or biological compounds, e.g. drugs, cosmetics for testing non-proliferative effects on cell motility
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- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57484—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
- G01N33/57492—Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds localized on the membrane of tumor or cancer cells
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- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/689—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to pregnancy or the gonads
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- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
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- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/21—Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
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- C07K2317/54—F(ab')2
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- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
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Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562199571P | 2015-07-31 | 2015-07-31 | |
| US62/199,571 | 2015-07-31 | ||
| PCT/IB2016/054584 WO2017021857A1 (en) | 2015-07-31 | 2016-07-29 | Motile sperm domain containing protein 2 and cancer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN108135933A CN108135933A (zh) | 2018-06-08 |
| CN108135933B true CN108135933B (zh) | 2022-04-29 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201680044577.XA Active CN108135933B (zh) | 2015-07-31 | 2016-07-29 | 含有活动精子结构域的蛋白质2和癌症 |
Country Status (10)
| Country | Link |
|---|---|
| US (2) | US20190040150A1 (enExample) |
| EP (2) | EP3328401B1 (enExample) |
| JP (1) | JP6949818B2 (enExample) |
| CN (1) | CN108135933B (enExample) |
| AU (1) | AU2016303474B2 (enExample) |
| CA (1) | CA2991868C (enExample) |
| ES (1) | ES2839456T3 (enExample) |
| IL (1) | IL257260B (enExample) |
| NZ (1) | NZ738875A (enExample) |
| WO (1) | WO2017021857A1 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2991868C (en) | 2015-07-31 | 2025-05-27 | Vascular Biogenics Ltd | PROTEIN 2 CONTAINING THE MOTILE SPERM DOMAIN AND CANCER |
| EP3328408B1 (en) | 2015-07-31 | 2020-10-07 | Vascular Biogenics Ltd. | Motile sperm domain containing protein 2 and inflammation |
| TWI808055B (zh) | 2016-05-11 | 2023-07-11 | 美商滬亞生物國際有限公司 | Hdac 抑制劑與 pd-1 抑制劑之組合治療 |
| TWI794171B (zh) | 2016-05-11 | 2023-03-01 | 美商滬亞生物國際有限公司 | Hdac抑制劑與pd-l1抑制劑之組合治療 |
| WO2018134254A1 (en) | 2017-01-17 | 2018-07-26 | Heparegenix Gmbh | Protein kinase inhibitors for promoting liver regeneration or reducing or preventing hepatocyte death |
| CA3093633A1 (en) * | 2018-03-13 | 2019-09-19 | Vascular Biogenics Ltd. | Bispecific antibodies to mospd2 and t cell- or nk cell-specific molecules |
| EP3597193A1 (en) * | 2018-07-16 | 2020-01-22 | Universitat Autònoma de Barcelona | Therapeutic use of afatinib in cancer |
| CA3191242A1 (en) * | 2020-09-10 | 2022-03-17 | Itzhak Mendel | Motile sperm domain containing protein 2 antibodies and methods of use thereof |
| EP4313146A4 (en) * | 2021-03-29 | 2025-04-02 | ImmuneWalk Therapeutics, Inc. | MOTILE SPERM DOMAIN CONTAINING PROTEIN 2, INTEGRIN BETA2, AND CD63 |
Citations (6)
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| JP2006151902A (ja) * | 2004-11-30 | 2006-06-15 | Akita Prefecture | 癌転移抑制用トリテルペン誘導体及び該トリテルペン誘導体を用いた癌転移抑制用組成物 |
| CN100515497C (zh) * | 2001-12-19 | 2009-07-22 | 研究发展基金会 | 脂质体输送以维生素e为基础的化合物 |
| JP2012507577A (ja) * | 2008-11-06 | 2012-03-29 | ヴァスキュラー バイオジェニックス リミテッド | 酸化脂質化合物およびその使用 |
| CN103037855A (zh) * | 2010-08-05 | 2013-04-10 | 植物制药科学公司良姜鸦片酊研究所 | 用于治疗癌症的包含视黄醇、其前体或反应产物和来自至少一种春黄菊植物的植物提取物的组合物 |
| CN104066706A (zh) * | 2011-12-12 | 2014-09-24 | 脉管生物生长有限公司 | 炎症的治疗 |
| CN103592432B (zh) * | 2013-10-15 | 2015-06-03 | 重庆市公安局 | 一种免疫磁珠分离精子与上皮细胞混合斑中精子的方法 |
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| CA3191242A1 (en) | 2020-09-10 | 2022-03-17 | Itzhak Mendel | Motile sperm domain containing protein 2 antibodies and methods of use thereof |
| EP4313146A4 (en) | 2021-03-29 | 2025-04-02 | ImmuneWalk Therapeutics, Inc. | MOTILE SPERM DOMAIN CONTAINING PROTEIN 2, INTEGRIN BETA2, AND CD63 |
-
2016
- 2016-07-29 CA CA2991868A patent/CA2991868C/en active Active
- 2016-07-29 CN CN201680044577.XA patent/CN108135933B/zh active Active
- 2016-07-29 EP EP16832394.7A patent/EP3328401B1/en active Active
- 2016-07-29 WO PCT/IB2016/054584 patent/WO2017021857A1/en not_active Ceased
- 2016-07-29 EP EP20173680.8A patent/EP3735977A1/en active Pending
- 2016-07-29 AU AU2016303474A patent/AU2016303474B2/en active Active
- 2016-07-29 US US15/747,920 patent/US20190040150A1/en not_active Abandoned
- 2016-07-29 NZ NZ738875A patent/NZ738875A/en unknown
- 2016-07-29 JP JP2018504932A patent/JP6949818B2/ja active Active
- 2016-07-29 ES ES16832394T patent/ES2839456T3/es active Active
- 2016-07-29 IL IL257260A patent/IL257260B/en unknown
-
2020
- 2020-10-13 US US17/068,959 patent/US11945875B2/en active Active
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| JP2006151902A (ja) * | 2004-11-30 | 2006-06-15 | Akita Prefecture | 癌転移抑制用トリテルペン誘導体及び該トリテルペン誘導体を用いた癌転移抑制用組成物 |
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| CN104066706A (zh) * | 2011-12-12 | 2014-09-24 | 脉管生物生长有限公司 | 炎症的治疗 |
| CN103592432B (zh) * | 2013-10-15 | 2015-06-03 | 重庆市公安局 | 一种免疫磁珠分离精子与上皮细胞混合斑中精子的方法 |
Non-Patent Citations (5)
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|---|---|
| EP3328401B1 (en) | 2020-10-14 |
| ES2839456T3 (es) | 2021-07-05 |
| US20210095044A1 (en) | 2021-04-01 |
| CA2991868C (en) | 2025-05-27 |
| JP2018527333A (ja) | 2018-09-20 |
| IL257260A (en) | 2018-03-29 |
| JP6949818B2 (ja) | 2021-10-13 |
| US11945875B2 (en) | 2024-04-02 |
| CN108135933A (zh) | 2018-06-08 |
| EP3735977A1 (en) | 2020-11-11 |
| EP3328401A1 (en) | 2018-06-06 |
| AU2016303474B2 (en) | 2022-06-16 |
| EP3328401A4 (en) | 2019-03-20 |
| HK1254515A1 (en) | 2019-07-19 |
| US20190040150A1 (en) | 2019-02-07 |
| CA2991868A1 (en) | 2017-02-09 |
| NZ738875A (en) | 2023-06-30 |
| WO2017021857A1 (en) | 2017-02-09 |
| AU2016303474A1 (en) | 2018-02-01 |
| IL257260B (en) | 2022-09-01 |
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