CN108096407A - A kind of external preparation for treating newborn addiction and preparation method thereof - Google Patents
A kind of external preparation for treating newborn addiction and preparation method thereof Download PDFInfo
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Abstract
The invention discloses a kind of external preparations for treating newborn addiction and preparation method thereof, and the external preparation is mainly prepared by dewdrop grass, the tuber of pinellia, pangolin, Snakegourd Fruit and frankincense.The external preparation has effects that softening and resolving hard mass, activating blood circulation and reducing swelling, clearing heat and detoxicating.Available for the proliferation of mammary gland, lump in breast tubercle etc., and curative effect is apparent, easily effects a radical cure, treatment cycle is short, Small side effects.
Description
Technical field
The present invention relates to a kind of external preparation for treating newborn addiction and preparation method thereof, belong to the field of drug technology.
Technical background
Newborn addiction, names of disease of tcm.It is to have shape lump not of uniform size with breast, pain is related as mainly with the menstrual cycle
The benign proliferative diseases of the breast tissue of performance.Can it occur throughout the year.30-50 years old women are apt to occur in, account for whole breasts
The 75% of gland disease is clinically most common breast disease.This disease has certain canceration danger.Doctor trained in Western medicine is then known as mammary gland capsule
Hyperplasia disease.If this disease early diagnoses, the state of an illness is lighter, treats in time, general prognosis bona.But also oriented Cancer Transitions.To trouble
The live and work of person causes great pain.
Western medical treatment is usually used in the method for the newborn addiction for the treatment of common at present, and there are two types of methods for this disease of western medical treatment：One
It is that lump diameter gives antituberculosis drugs treat within 0.5cm；Second is that lump diameter patient more than 1.0 gives operation and controls
It treats.Doctor trained in Western medicine antituberculosis drugs treat, palliative although quick, therapeutic effect is undesirable, long-term, resistive connection repeatedly
Core western medicine improves the drug resistance of body, high recurrence rate, endangers the physical and mental health of people.Expenses of surgical treatment is high, pain
Greatly, healing is slow, adds the burden of patient.
The content of the invention：
The purpose of the present invention is to provide a kind of external preparation for treating newborn addiction and preparation method thereof.The external preparation has soft
Hard dissipating bind, activating blood circulation and reducing swelling, it is clearing heat and detoxicating the effect of.Available for the proliferation of mammary gland, lump in breast tubercle etc., and curative effect is apparent, Yi Gen
It controls, treatment cycle is short, Small side effects.
In order to solve the above technical problems, the present invention is realized using following technical scheme：A kind of external preparation for treating newborn addiction,
Calculate by weight, by 350-450 parts of dewdrop grass, 350-450 parts of the tuber of pinellia, 150-250 parts of pangolin, 150-250 parts of Snakegourd Fruit and
150-250 parts of frankincense is prepared.
In the external preparation of the newborn addiction of foregoing treatment, calculate by weight, by 380-420 parts of dewdrop grass, tuber of pinellia 380-420
Part, 180-220 parts of pangolin, 180-220 parts of Snakegourd Fruit and 180-220 parts of frankincense are prepared.
In the external preparation of the newborn addiction of foregoing treatment, calculate by weight, by 400 parts of dewdrop grass, 400 parts of the tuber of pinellia, wear mountain
200 parts of 200 parts of first, 200 parts of Snakegourd Fruit and frankincense are prepared.
In the external preparation of the newborn addiction of foregoing treatment, the external preparation is patch or paste.
In the external preparation of the newborn addiction of foregoing treatment, when the external preparation is patch, matrix is further included, the matrix is pressed
According to listed as parts by weight, by 50-90 parts of sorbierite, 60-100 parts of glycerine, 60-100 parts of stearic acid, 50-90 parts of tristearin, yellow petroleum jelly
20-40 parts, 5-15 parts of sucrose stearate, 10-30 parts of lanolin, -100 parts of polysorbate 60,3-9 parts of benzoic acid and oxybenzene second
Ester 1-2 is formed.
In the external preparation of the foregoing newborn addiction for the treatment of, the matrix is calculated in parts by weight, by 60-80 parts of sorbierite, sweet
70-90 parts oily, 70-90 parts of stearic acid, 60-80 parts of tristearin, 25-35 parts of yellow petroleum jelly, 8-12 parts of sucrose stearate, lanolin
1-2 parts of 15-25 parts, 70-90 parts of polysorbate, 5-7 parts of benzoic acid and ethyl hydroxy benzoate form.
In the external preparation of the newborn addiction of foregoing treatment, the matrix is calculated in parts by weight, by 70 parts of sorbierite, glycerine 80
Part, 80 parts of stearic acid, 70 parts stearic, 30 parts of yellow petroleum jelly, 10 parts of sucrose stearate, 20 parts of lanolin, polyoxyethylene sorbitan monoleate part,
1.5 parts of compositions of 6 parts of benzoic acid and ethyl hydroxy benzoate.
In the external preparation of the newborn addiction of foregoing treatment, dewdrop grass, the tuber of pinellia wear mountain and Snakegourd Fruit, and 2 are extracted with the ethyl alcohol of 55-65%
Secondary, 4-8 times of first time measures, extraction 1.5-2.5 it is small when, second 3-5 times measure, extraction 1.5-2.5 it is small when, filtration, merging filtrate,
The medicinal extract of relative density 1.1-1.2 when ethyl alcohol and concentration are 60-65 DEG C is recycled, is let cool；Frankincense is added in, grinds to fusing, obtains drug
Medicinal extract；Weigh recipe quantity sorbierite, glycerine, stearic acid, tristearin, yellow petroleum jelly, sucrose stearate, lanolin, polysorbate,
Benzoic acid, ethyl hydroxy benzoate are heated to melting, and stirring, mixing obtain matrix, matrix and said medicine medicinal extract mixing to get.
In the external preparation of the newborn addiction of foregoing treatment, the paste is prepared：Dewdrop grass, the tuber of pinellia wear mountain and Snakegourd Fruit,
It is extracted 2 times with 60% ethyl alcohol, for the first time 6 times of amounts, when extraction 2 is small, second of 4 times of amount, when extraction 2 is small, filtration, merging filtrate,
The medicinal extract of relative density 1.1-1.2 when ethyl alcohol and concentration are 60-65 DEG C is recycled, is let cool；Add in frankincense, grind to fusing to get.
External preparation medicinal extract of the present invention is prepared by dewdrop grass, the tuber of pinellia, pangolin and Snakegourd Fruit.Wherein, horseshoe
Gold（Dichondra repens Forst.）, bitter, pungent, cold nature, owner's lung channel and stomach have clearing heat and detoxicating, Li Shui,
The effect of promoting blood circulation is Miao ethnic group resourceful simply medicinal material among the people, has and develops and utilizes value well.The tuber of pinellia（Scientific name：
Pinellia ternata）, there is the effect of eliminating dampness and eliminating phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass.Available for abundant expectoration cough and asthma, phlegm and retained fluid is dizzy
Throb with fear, anemophlegmatic vertigo, phlegm and headache, vomiting gastric disorder causing nausea, chest gastral cavity ruffian, globus hysteriocus；Raw controlling outward carbuncle swells subcutaneous nodule.Pangolin category（Scientific name：
Manis）, it is that one of Pholidota pangolin section belongs to, nature and flavor：Taste is salty, cold nature, channel tropism：Return liver, stomach.Can invigorate blood circulation, stagnation resolvation,
Breast, detumescence are drawn out the pus under dissipating bind, the carbuncle that disappears, promoting menstruation；For blood stasis, abdominal mass, arthralgia pain due to rheumatism, agalactia, carbuncle swells, scrofula etc.
Disease.Snakegourd Fruit,（Trichosanthes kirilowii Maxim.）, it is perennial to climb type herbaceous plant.It cures mainly：Clearing away heat and eliminating phlegm,
Relieving stuffiness of the chest by dispersing aggregation of pathogens, moisturize laxation.For cough with lung heat, the turbid Huang of phlegm is thick, chest impediment and cardialgia, accumulation of pathogens in chest feeling of fullness, acute mastitis, lung carbuncle, acute appendicitis swelling and pain,
Constipation.
Dewdrop grass acrid flavour is cold in nature in side, there is the work(of clearing heat and detoxicating Li Shui promoting blood circulations；Tuber of pinellia acrid flavour is warm-natured, returns spleen, lung channel, pungent
Warm logical, eliminating dampness promoting the circulation of qi is dissipated, energy expectorant powder junction dissipates pain detumescence, and external application energy detoxification sore treatment is kind to control emulsifiable paste；The two phase 5 is monarch drug in a prescription altogether.
Frankincense acrid, bitter, warm, perfume is strong to walk to alter, can dispersing blood stasis blood, degrading the channel, scattered cult poison, swelling and pain relieving；Pangolin is apt to walk to alter, without it is micro- not
Extremely, the stasis of blood that can manage it is stagnant, eliminating mass product, and taste saltiness is trembled with fear, can apocenosis blood, change slough.Withering property of melon is sweet, bitter, relieving stuffiness of the chest by dispersing aggregation of pathogens, dissipates and controls newborn pain；
It is adjuvant altogether.All medicine phases 5, gather altogether softening and resolving hard mass, activating blood circulation and reducing swelling, it is clearing heat and detoxicating the benefits of.
Matrix is by sorbierite, glycerine, stearic acid, tristearin, yellow petroleum jelly, sucrose stearate, sheep used in patch of the present invention
Hair fat, polysorbate, benzoic acid and ethyl hydroxy benzoate are prepared.Wherein, D-sorbite, alias sorbierite.English name
Sorbitol、D-Glucitol、Sorbol、D-Sorbitol.Molecular formula is C6H14O6, molecular weight 182.17.It is inhaled for white
Moist powder or crystalline powder, sheet or particle, it is odorless, as toothpaste, cosmetics, tobacco conditioning agent.Glycerine, colourless, nothing
Smelly, sweet, appearance is in clear and bright viscous liquid state, is a kind of organic matter.In terms of medicine, to produce various preparations, solvent, moisture absorption
Agent, antifreezing agent and sweetener, ingredients externally-applied ointment or suppository etc..Stearic acid, i.e. octadecanoid acid are widely used in inhibition and generation cosmetic, modeling
Expect cold resistant plasticizer, releasing agent, stabilizer, surfactant, thiofide, waterproofing agent, polishing agent, metallic soap, gold
Belong to mineral flotation agent, softening agent, pharmaceuticals and other organic chemicals.Tristearin is a kind of chemical substance, and molecular formula is
C57H110O6, as food emulsifying agent.It is also used for cosmetics, the industries such as soap and candle.Yellow petroleum jelly is faint yellow or yellow
Uniform soft paste；It is odorless or almost odorless；There is soapy feeling with skin contact；Sucrose stearate, English name:
Sucrose stearate ester, colourless or slight- yellow thick liquid or powder, it is tasteless, water is slightly soluble in, is dissolved in ethyl alcohol；It can make
Emulsifier, wetting agent, dispersant, solubilizer and emollient etc..Make emulsifier for cosmetics, food, medical industry, make food
Dosage is 1~1.5g/kg when emulsifier and food preservative.It can be additionally used in detergent, fiber process, farming and animal husbandry and tin product
Deng.Lanolin is attached to a kind of secretion grease on wool, is faint yellow or brown color soft paste；There is stickiness and slide
It is greasy；It is smelly faint and special.It is readily soluble in chloroform or ether, it is dissolved in hot ethanol, in ethanol soluble,very slightly.Lanolin can be with
Make skin smooth tender.It is pharmaceutically used to prepare plaster for curing rheumatism, zinc oxide adhesive plaster and ointment base.Cosmetics-stage lanolin can use
In cold cream, crease-proof cream, chapstick, shampoo paste, hair conditioner, hair-cream, lipstick and advanced perfumed soap etc..It is commonly used for water-in-oil emulsion
Agent is excellent moistness substance.The dry or rough skin when lacking natural moisture can be made to soften and be restored.Poly- mountain
Pear ester is faint yellow to orange-yellow thick liquid, and a sense of warmth is used as the solubilizer or emulsifier of parenteral solution and oral liquid；Glue
Wafer dispersant；Ointment emulsifier and matrix；Suppository base etc..It is used as emulsifier in the food industry.Benzoic acid
For flakey or acicular crystal with benzene or the smell of formaldehyde, benzoic acid can make Whitfield's Ointment, benzoic acid
Unguentum acidi salicylici is the medicament made of addition lanolin, yellow petroleum jelly using benzoic acid, salicylic acid as primary raw material.Wherein, benzene first
Acid is combined with salicylic acid, can treat adult skin nosomycosis, the mycotic infection of superficial part such as diseases such as ringworm of the body, the tinea manuum and tinea pedis.4-
Nipagin A, for white crystalline powder, the preservative as food, drug and cosmetics.
The present invention uses more than raw material that medicine patch matrix is made according to present invention proportioning, and manufactured medicinal plaster stroma can
Make Marjoram Extract, accelerate blood circulation, while make body interior warm, relax one's muscles, drive the oxygen of capillary network and support
Divide and exchange, and exclude to accumulate the agings such as in vivo fatigue substances and lactic acid waste to swelling in elimination, made of this external application matrix
Patch plasticity is good, without pullling dermal sensation when movable, and is easily peeled off, painless, skin situation without exception after stripping.
Treat example statistics
1 patient and method
1.1 patients 36 breast addiction patient, married 25, unmarried 11, age 27-50 Sui, eumenorrhea 15, abnormal 21
Example, patient have different degrees of breast pain and lump in varying numbers, not of uniform size.Exclude physiological breast pain.
1.2.1 use drug of the present invention（It is prepared by embodiment 1）It is affixed at the proliferation of mammary gland, 3d is changed once, 1 month
For 1 course for the treatment of, 2 courses for the treatment of judge curative effect.
1.3 observation index observe pretherapy and post-treatment pain and the situation of change of lump.
1.4 effective standards are cured：Pain and lump disappear, and 3 months do not recur；Effectively：Newborn pain disappearance or apparent
Mitigate, lump softens or reduces；It is invalid：Lump softens or reduces;It is invalid.
2 results
2.1 pretherapy and post-treatment symptom improvement, which are compared, is shown in Table 1.
By table l as it can be seen that using after drug of the present invention, pain and lump can preferably be improved.
2.2 curative effect
After treatment 2 months, Cure is counted, the results are shown in Table 2.
By table 2 as it can be seen that drug of the present invention can treat the breast pain and lump of newborn addiction breaking-out, curative effect affirmative.
3 certain embodiments
Liu, female, 30 years old, double mammary swelling pain caking recurrent exerbations 2 years aggravated 1 month, pain is radiated to oxter, shoulder back.Through
Phase aggravates.Chest is certainly coerced swollen usually, and food of receiving is general, is apt to strongly fragrant irritability, swollen breasts, whenever mood is not smooth or premenstrual symptom adds
Weight.It checks:Right breast outside upper quadrant touches 3cm × 2cm size tabular morphology lumps, and pliable, tenderness is not shown,
Color of the leather is normal, and what is pushed away is removable；Left breast touches inner upper quadrant and touches 3cm × 1cm size bar rope shape lumps, and quality is slightly
Firmly, tenderness, color of the leather is normal, and what is pushed away is removable.Axillary lymph knot does not touch enlargement, and infrared ray galactophore scanning prompts bilateral breast
Glandular lobule hyperplasia.Pale tongue
Red tongue is thin white, veins string.With drug of the present invention（By embodiment 1 preparing）It is affixed at the proliferation of mammary gland, 3d 1 is changed.Even
2 course for the treatment of breast pains of patch and lump disappear substantially.
Mr. Wang, female, 35 years old, double mammary swelling pain caking recurrent exerbations 1 year.With drug of the present invention（By embodiment 1 making
It is standby）It is affixed at the proliferation of mammary gland, 3d 1 is changed.After 1 month, pain mitigates, and lump softens, and after 2 months, pain and lump disappear.
And 3 months do not recur.
Liu, female, 25 years old, double mammary swelling pain caking recurrent exerbations 1 year.With drug of the present invention（By embodiment 1 making
It is standby）It is affixed at the proliferation of mammary gland, 3d 1 is changed.After 1 month, breast pain disappears, and lump softens, and after 2 months, pain and lump disappear.
Liu, female, 37 years old, double mammary swelling pain caking recurrent exerbations 3 years.With drug of the present invention（By embodiment 1 making
It is standby）It is affixed at the proliferation of mammary gland, 3d 1 is changed.After 1 month, lump softens, and after 2 months, breast pain is substantially reduced, and lump softens.3
Pain and lump disappear after month.
Mr. Wang, female, 52 years old, double mammary swelling pain caking recurrent exerbations 1 year.With drug of the present invention（By embodiment 1 making
It is standby）It is affixed at the proliferation of mammary gland, 3d 1 is changed.After 1 month, breast pain disappears, and lump softens, and after 2 months, pain and lump disappear.
Experimental example 2：Performance study
1 research project：Drug of the present invention is made by embodiment 1.
2 viscosities are tested.
Hold the measure of viscous force by《Chinese Pharmacopoeia》2010 editions Ⅹ II E emplastrums of an annex stick amylograph（Second
Method holds the measure of viscous force）It measures, the results are shown in Table 3；
Peel strength is pressed《Chinese Pharmacopoeia》2010 editions Ⅹ II E emplastrums of an annex stick amylograph（3rd method is removed strong
The measure of degree）It measures, the results are shown in Table 3.
Conclusion：Drug viscosity of the present invention meets the requirements, and stickiness is moderate, and lotion plasticity is preferable, and affinity is strong, to skin
Irritation is small.
3 skin irritation tests.
Please 20 professionals carry out it is blank feel scoring, hundred-mark system takes geometrical mean.It the results are shown in Table 4.
Scoring such as table 5：
As seen from table, pharmaceutical properties of the present invention are good.
Compared with prior art, external preparation of the present invention has softening and resolving hard mass, activating blood circulation and reducing swelling, clearing heat and detoxicating work(
Effect.Available for the proliferation of mammary gland, lump in breast tubercle etc..Matrix of the present invention can make Marjoram Extract, accelerate blood circulation, make simultaneously
Body interior is warm, relaxs one's muscles, and the oxygen and nutrient for driving capillary network exchange, and exclude to accumulate in vivo fatigue substances and
For the agings such as lactic acid waste to swelling in elimination, medicine patch plasticity made of this external application matrix is good, without pullling skin sense when movable
Feel, and be easily peeled off, painless, skin situation without exception after stripping.Drug extract of the present invention coordinates medicinal plaster of the present invention
Patch made of matrix not only has effects that softening and resolving hard mass, activating blood circulation and reducing swelling, clearing heat and detoxicating, also has the rapid, good effect that works
The characteristics of.
Invention is further described with reference to embodiment, but is not intended as the foundation limited the present invention.
Specific embodiment：
Embodiment 1
Drug extract prescription：Dewdrop grass 400g, tuber of pinellia 400g, frankincense 200g, pangolin 200g and Snakegourd Fruit 200g.
Matrix formulations：Sorbierite 70g, glycerine 80g, stearic acid 80g, tristearin 70g, yellow petroleum jelly 30g, sucrose stearate
10g, lanolin 20g, polyoxyethylene sorbitan monoleate g, benzoic acid 6g and ethyl hydroxy benzoate 1.5g.
The production method of patch：Dewdrop grass, the tuber of pinellia, pangolin and Snakegourd Fruit are extracted 2 times with 60% ethyl alcohol, 6 times for the first time
Amount, when extraction 2 is small, second of 4 times of amount, when extraction 2 is small, filtration, merging filtrate recycles ethyl alcohol and concentrates as relative density 1.2
Medicinal extract（60℃）, let cool；It adds in frankincense to grind to fusing, obtains drug extract, it is spare；Weigh recipe quantity sorbierite, glycerine, tristearin
Acid, tristearin, yellow petroleum jelly, sucrose stearate, lanolin, polysorbate, benzoic acid and ethyl hydroxy benzoate, are heated to melting, stir
Mix, mixing, obtain matrix, matrix and said medicine medicinal extract mixing, be made 1000 patches to get.
Usage and dosage：External application is affixed at the proliferation of mammary gland, and 3d is changed once.
Embodiment 2
Drug extract prescription：Dewdrop grass 420g, tuber of pinellia 420g, pangolin 220g, Snakegourd Fruit 220g and frankincense 220g.
Matrix formulations：Sorbierite 80g, glycerine 90g, stearic acid 90g, tristearin 80g, yellow petroleum jelly 35g, sucrose stearate
12g, lanolin 25g, polysorbate 90g, benzoic acid 7g and ethyl hydroxy benzoate 2g.
The production method of patch：Dewdrop grass, the tuber of pinellia wear mountain and Snakegourd Fruit, are extracted 2 times with 65% ethyl alcohol, for the first time 8 times of amounts, extraction
2.5 it is small when, second 5 times of amounts, when extraction 2.5 is small, filtration, merging filtrate, recycle ethyl alcohol and concentrate for 60-65 DEG C when it is relatively close
The medicinal extract of 1.1-1.2 is spent, is let cool；Frankincense is added in, grinds to fusing, obtains drug extract, it is spare；Weigh recipe quantity sorbierite, glycerine,
Stearic acid, tristearin, yellow petroleum jelly, sucrose stearate, lanolin, polysorbate, benzoic acid and ethyl hydroxy benzoate are heated to melting
Melt, stirring, mixing obtain matrix, matrix and said medicine medicinal extract mixing, be made 1000 patches to get.
Usage and dosage：External application is affixed at the proliferation of mammary gland, and 3d is changed once.
Embodiment 3
Paste prescription：Dewdrop grass 380g, tuber of pinellia 380g, pangolin 180g, Snakegourd Fruit 180g and frankincense 180g.
Paste production method：Dewdrop grass, the tuber of pinellia wear mountain and Snakegourd Fruit, are extracted 2 times with 55% ethyl alcohol, 4 times of amounts, carry for the first time
Take 1.5 it is small when, second 3 times of amounts, when extraction 1.5 is small, filtration, merging filtrate, recycle ethyl alcohol and concentrate for 60-65 DEG C when it is opposite
The medicinal extract of density 1.1-1.2, lets cool；Add in frankincense, grind to fusing to get.
Usage and dosage：External application is applied at the proliferation of mammary gland, and 3d is changed once.
Claims (9)
1. a kind of external preparation for treating newborn addiction, it is characterised in that：It calculates by weight, mainly by 350-450 parts of dewdrop grass, half
150-250 parts of summer 350-450 part, 150-250 parts of pangolin, 150-250 parts of Snakegourd Fruit and frankincense are prepared.
2. the external preparation of the newborn addiction for the treatment of as described in claim 1, it is characterised in that：It calculates by weight, mainly by horseshoe
180-220 parts of 380-420 parts golden, 380-420 parts of the tuber of pinellia, 180-220 parts of pangolin, 180-220 parts of Snakegourd Fruit and frankincense prepare and
Into.
3. the external preparation of the newborn addiction for the treatment of as claimed in claim 2, it is characterised in that：It calculates by weight, mainly by horseshoe
200 parts of 400 parts of gold, 400 parts of the tuber of pinellia, 200 parts of pangolin, 200 parts of Snakegourd Fruit and frankincense are prepared.
4. the external preparation of the newborn addiction for the treatment of as any one of claim 1-3, it is characterised in that：The external preparation is
Patch or paste.
5. the external preparation of the newborn addiction for the treatment of as claimed in claim 4, it is characterised in that：When the external preparation is patch, also
Including matrix, the matrix is calculated in parts by weight, by 50-90 parts of sorbierite, 60-100 parts of glycerine, 60-100 parts of stearic acid,
50-90 parts stearic, 20-40 parts of yellow petroleum jelly, 5-15 parts of sucrose stearate, 10-30 parts of lanolin, polysorbate 60-100
Part, 3-9 parts of benzoic acid and ethyl hydroxy benzoate 1-2 compositions.
6. the external preparation of the newborn addiction for the treatment of as claimed in claim 5, it is characterised in that：The matrix is calculated in parts by weight,
It is hard by 60-80 parts of sorbierite, 70-90 parts of glycerine, 70-90 parts of stearic acid, 60-80 parts of tristearin, 25-35 parts of yellow petroleum jelly, sucrose
1-2 parts of 8-12 parts of resin acid ester, 15-25 parts of lanolin, 70-90 parts of polysorbate, 5-7 parts of benzoic acid and ethyl hydroxy benzoate compositions.
7. the external preparation of the newborn addiction for the treatment of as claimed in claim 6, it is characterised in that：The matrix is calculated in parts by weight,
By 70 parts of sorbierite, 80 parts of glycerine, 80 parts of stearic acid, 70 parts stearic, 30 parts of yellow petroleum jelly, 10 parts of sucrose stearate, wool
1.5 parts of 20 parts of fat, polyoxyethylene sorbitan monoleate part, 6 parts of benzoic acid and ethyl hydroxy benzoate compositions.
8. the external preparation of the newborn addiction for the treatment of as any one of claim 5-7, it is characterised in that：Dewdrop grass, the tuber of pinellia are worn
Mountain and Snakegourd Fruit are extracted 2 times with the ethyl alcohol of 55-65%, and 4-8 times of first time measures, when extraction 1.5-2.5 is small, second 3-5 times measure, carry
When taking 1.5-2.5 small, filtration, merging filtrate recycles the medicinal extract of relative density 1.1-1.2 when ethyl alcohol and concentration are 60-65 DEG C, puts
It is cold；Frankincense is added in, grinds to fusing, obtains drug extract；Weigh recipe quantity sorbierite, glycerine, stearic acid, tristearin, yellow petroleum jelly, sugarcane
Sugared stearate, lanolin, polysorbate, benzoic acid, ethyl hydroxy benzoate are heated to melting, and stirring, mixing obtain matrix, matrix with
Said medicine medicinal extract mixing to get.
9. the external preparation of the newborn addiction for the treatment of as claimed in claim 8, it is characterised in that：The paste is prepared：Horseshoe
Gold, the tuber of pinellia wear mountain and Snakegourd Fruit, are extracted 2 times with 60% ethyl alcohol, for the first time 6 times of amounts, when extraction 2 is small, second of 4 times of amount, and extraction 2
Hour, filtration, merging filtrate recycles the medicinal extract of relative density 1.1-1.2 when ethyl alcohol and concentration are 60-65 DEG C, lets cool；Add in breast
Perfume (or spice), grind to fusing to get.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810136793.8A CN108096407A (en) | 2018-02-09 | 2018-02-09 | A kind of external preparation for treating newborn addiction and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810136793.8A CN108096407A (en) | 2018-02-09 | 2018-02-09 | A kind of external preparation for treating newborn addiction and preparation method thereof |
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| Publication Number | Publication Date |
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| CN108096407A true CN108096407A (en) | 2018-06-01 |
Family
ID=62205550
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810136793.8A Withdrawn CN108096407A (en) | 2018-02-09 | 2018-02-09 | A kind of external preparation for treating newborn addiction and preparation method thereof |
Country Status (1)
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| CN (1) | CN108096407A (en) |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101623323A (en) * | 2008-07-08 | 2010-01-13 | 吴彦勇 | Chinese medicinal composition for treating hyperplasia of mammary glands |
| US20110250259A1 (en) * | 2010-04-12 | 2011-10-13 | Kevin Buckman | Method of treating and preventing breast diseases and breast cancer with medicated formula |
| CN106581380A (en) * | 2015-10-14 | 2017-04-26 | 贵州瑞和制药有限公司龙里药厂 | External preparation capable of promoting blood circulation to remove blood stasis and preparation method of external preparation |
-
2018
- 2018-02-09 CN CN201810136793.8A patent/CN108096407A/en not_active Withdrawn
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101623323A (en) * | 2008-07-08 | 2010-01-13 | 吴彦勇 | Chinese medicinal composition for treating hyperplasia of mammary glands |
| US20110250259A1 (en) * | 2010-04-12 | 2011-10-13 | Kevin Buckman | Method of treating and preventing breast diseases and breast cancer with medicated formula |
| CN106581380A (en) * | 2015-10-14 | 2017-04-26 | 贵州瑞和制药有限公司龙里药厂 | External preparation capable of promoting blood circulation to remove blood stasis and preparation method of external preparation |
Non-Patent Citations (1)
| Title |
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| 贾孟辉 等: "乳酥膏外敷治疗乳腺疾病103例", 《陕西中医》 * |
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