CN108096377A - Neulized inhalation liquid that a kind of peri-operation period uses and preparation method thereof - Google Patents

Neulized inhalation liquid that a kind of peri-operation period uses and preparation method thereof Download PDF

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Publication number
CN108096377A
CN108096377A CN201810184713.6A CN201810184713A CN108096377A CN 108096377 A CN108096377 A CN 108096377A CN 201810184713 A CN201810184713 A CN 201810184713A CN 108096377 A CN108096377 A CN 108096377A
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neulized inhalation
inhalation liquid
peri
mentioned
operation period
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蒋丽丽
陈磊
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Affiliated Hospital of University of Qingdao
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Affiliated Hospital of University of Qingdao
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/51Gentianaceae (Gentian family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/04Sulfur, selenium or tellurium; Compounds thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/11Pteridophyta or Filicophyta (ferns)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/486Millettia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/65Paeoniaceae (Peony family), e.g. Chinese peony
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/708Rheum (rhubarb)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815Lycium (desert-thorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/007Pulmonary tract; Aromatherapy
    • A61K9/0073Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/53Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

Abstract

Neulized inhalation liquid used the invention discloses a kind of peri-operation period and preparation method thereof, raw medicinal material include japanese tripterospermum herb 15%, Herba Solani Lyrati 15%, Sargent gloryvine 12%, rheum officinale 10%, saltcake 8%, Medicated Leaven 10%, moutan bark 4%, the radix paeoniae rubrathe 6%, Entada phaseoloides 13% and the fruit of Chinese wolfberry 7%.Neulized inhalation liquid that the peri-operation period uses and preparation method thereof, by using japanese tripterospermum herb, Herba Solani Lyrati, Sargent gloryvine, rheum officinale, saltcake, Medicated Leaven, moutan bark, the radix paeoniae rubrathe, Entada phaseoloides and the fruit of Chinese wolfberry, japanese tripterospermum herb, for cough due to wind-heat evil, jaundice, arthralgia pain due to rheumatism, and it is prepared into for pulmonary surgery in the complication of peri-operation period to have after Neulized inhalation liquid by above-mentioned Chinese medicine material and preferably treats conditioning effect, it can greatly reduce patient after Neulized inhalation liquid using the present invention and occur pulmonary infection after surgery, atelectasis, pulmonary edema, the probability that bronchitis and basic chronic pulmonary disease exacerbation happen, it is very beneficial for patient's quick recovery.

Description

Neulized inhalation liquid that a kind of peri-operation period uses and preparation method thereof
Technical field
The present invention relates to pharmaceutical technology fields, are specially Neulized inhalation liquid and its preparation side that a kind of peri-operation period uses Method.
Background technology
Peri-operation period is an overall process around operation, since patient determines to be treated surgically, to operative treatment Until basic rehabilitation, comprising in operation consent, operation and postoperative a period of time, in particular to from definite operative treatment, Until the treatment related with specifically performing the operation terminates substantially, about in the preoperative 5-7 days to postoperative 7-12 days time.
Lung is located at thoracic cavity, left and right each one, the position highest in viscera thus claim lung covering other viscera.Such as《Ling Shu Miraculous Pivot or Divine Axis nine kinds of needles is discussed》 It says:" lung person, the lid of the vital organs of the human body.”《It is said in Thorough Knowledge of Medicine through twelve interior organs's shape scape figure》It says:" it is lung under larynx, two leaves are lustrous and transparent in vain, meaning Canopy, it is empty such as beehive with all dirty again, it is lower without saturating key, therefore suctions is then full, the then void exhaled." illustrate position and shape of the ancients to lung State structure, which has, to be more apparent from.But " under without saturating key ", key should be changed to down, " suction then full " is because nasal cavity Pranaization and the Pranaization of lung act on, the result for expanding Prana bodies.
In recent years, healthcare givers is being stepped up the attention degree of peri-operation period, especially people when doing lungs operation, Before surgery or the improper surgical effect that can directly influence patient of postoperative conditioning and rehabilitation degree, in peri-operation period Common pulmonary complication also progressively displays, such as pulmonary infection, atelectasis, pulmonary edema, bronchitis and basis Chronic pulmonary disease exacerbation etc. is typically to be tackled using the method for Western medicine and injection currently for this problem, but by It is poor in the resistance of patient after surgery, and the side effect of Western medicine is larger, usually can cause other portions on patient body again The complication of position, and method is not still solved well currently for these problems of pulmonary surgery in peri-operation period.
The content of the invention
(1) the technical issues of solving
In view of the deficiencies of the prior art, the Neulized inhalation liquid used the present invention provides a kind of peri-operation period and its preparation side Method is solved and also progressively displayed in the common pulmonary complication of peri-operation period, such as pulmonary infection, atelectasis, lung's water Swollen, bronchitis and basic chronic pulmonary disease exacerbation etc., are typically using Western medicine and injection currently for this problem Method tackle, but the resistance due to patient after surgery is poor, and the side effect of Western medicine is larger, can usually draw again The complication at other positions on patient body is played, and is not still had very currently for these problems of pulmonary surgery in peri-operation period Good solves the problems, such as method.
(2) technical solution
To achieve the above object, the present invention provides following technical solution:A kind of Neulized inhalation liquid that peri-operation period uses and Its preparation method, raw medicinal material include japanese tripterospermum herb 15%, Herba Solani Lyrati 15%, Sargent gloryvine 12%, rheum officinale 10%, 8%, six god of saltcake Song 10%, moutan bark 4%, the radix paeoniae rubrathe 6%, Entada phaseoloides 13% and the fruit of Chinese wolfberry 7%, the preparation method of the Neulized inhalation liquid are as follows:
A1, above-mentioned raw materials medicinal material is taken according to regulation percentage, and above-mentioned medicinal material is placed in the warm water of certain temperature It impregnates 30-50 minutes.
A2, the raw medicinal material that will impregnate completion in step a1 take out, and are placed on centrifuge dripping in cartridge filter, by it is above-mentioned from Raw material after heart drying is ground into powder.
A3, gained raw material powder addition suitable quantity of water in step a2 in marmite is fried boiling, then is decocted 10-20 minutes with small fire, Afterwards by fried good above-mentioned raw material static placement a period of time.
A4, the well-done raw material aqueous solution of decocting of gained in step a3 is poured into mixing and stirring tank and is sufficiently stirred so that It is fully being merged between various raw medicinal material powder, then the solution that above-mentioned stirring is completed is being filtered using 120 mesh screens, gone Except particle larger in solution, you can completion prepares Neulized inhalation liquid, then the above-mentioned Neulized inhalation liquid prepared is dispensed .
Preferably, in the step a1 and above-mentioned medicinal material is placed in the warm water of certain temperature impregnates 30-50 minutes, institute The temperature for needing warm water is 45 degree.
Preferably, in the step a3 by fried good above-mentioned raw material it is static place a period of time, raw material are static The time of placement is 30 minutes.
(3) advantageous effect
Neulized inhalation liquid used the present invention provides a kind of peri-operation period and preparation method thereof, compared with prior art, The beneficial effects of the invention are as follows:Neulized inhalation liquid that the peri-operation period uses and preparation method thereof, by using japanese tripterospermum herb, ghost Mesh grass, Sargent gloryvine, rheum officinale, saltcake, Medicated Leaven, moutan bark, the radix paeoniae rubrathe, Entada phaseoloides and the fruit of Chinese wolfberry, Sargent gloryvine have removing toxicity for eliminating carbuncles, and promoting blood circulation stops Bitterly, dispelling wind and eliminating dampness, disinsection efficiency cure mainly acute appendicitis, dysentery, breast pain, arthralgia pain due to rheumatism, abdominal pain due to enterositosis, Chinese herb rhubarb have attack it is stagnant, Clearing away damp-heat, purging intense heat, cool blood, dissolving stasis and removing toxic substances and other effects, japanese tripterospermum herb, for cough due to wind-heat evil, jaundice, arthralgia pain due to rheumatism, roundworm Disease, wind and heat dispersing, invigorating spleen to remove dampness, desinsection, Herba Solani Lyrati can be used as heat-clearing, removing toxic substances and wind-damp dispelling, to control lung cancer, gastrointestinal tract Cancer and being prepared by above-mentioned Chinese medicine material after Neulized inhalation liquid has more preferably for pulmonary surgery in the complication of peri-operation period Treatment conditioning effect, using the present invention Neulized inhalation liquid after can greatly reduce patient occur after surgery pulmonary infection, The probability that atelectasis, pulmonary edema, bronchitis and basic chronic pulmonary disease exacerbation happen, it is quick to be very beneficial for patient Rehabilitation.
Specific embodiment
The technical solution in the embodiment of the present invention is clearly and completely described below, it is clear that described embodiment Only part of the embodiment of the present invention, instead of all the embodiments.Based on the embodiments of the present invention, the common skill in this field Art personnel all other embodiments obtained without making creative work belong to the model that the present invention protects It encloses.
The present invention provides a kind of technical solution:Neulized inhalation liquid that a kind of peri-operation period uses and preparation method thereof, raw material Medicinal material includes japanese tripterospermum herb 15%, Herba Solani Lyrati 15%, Sargent gloryvine 12%, rheum officinale 10%, saltcake 8%, Medicated Leaven 10%, moutan bark 4%th, the radix paeoniae rubrathe 6%, Entada phaseoloides 13% and the fruit of Chinese wolfberry 7%, the preparation method of Neulized inhalation liquid are as follows:Wherein, the removing toxic substances of Sargent gloryvine tool disappears Carbuncle, promoting blood circulation and stopping pain, dispelling wind and eliminating dampness, disinsection efficiency cure mainly acute appendicitis, dysentery, breast pain, dysmenorrhoea, Amenorrhea, traumatic injury, arthralgia pain due to rheumatism, Abdominal pain due to enterositosis.
Rheum officinale has and attacks stagnant, clearing away damp-heat, purging intense heat, cool blood, dissolving stasis and removing toxic substances and other effects.
Saltcake has relieving constipation by purgation, and moistening for dryness and softening hard mass, relieve inflammation or internal heat the effect of subsiding a swelling, and is usually used in real heat and stagnates, abdomen expires distending pain, greatly The treatment of the illnesss such as just constipation, acute appendicitis swelling and pain, controls acute mastitis, hemorrhoid gall outside.
Medicated Leaven is mainly used for strengthening the spleen and stomach, in the tune that helps digestion, cures mainly weakness of the spleen and the stomach, retention of food and drink, feeling of stuffiness in chest abdominal distension.
Moutan bark has clearing heat and cooling blood, activates blood circulation and disperses blood clots, reducing the asthenic fever and other effects, the small toxicity of moutan bark and paeonol.
The radix paeoniae rubrathe has the effect of clearing heat and cooling blood, promoting blood circulation.
Entada phaseoloides, expelling wind and eliminating dampness, relaxing tendons and activating collaterals, removing blood stasis and analgesics, diuresis.
The fruit of Chinese wolfberry, rich in polysaccharides, polysaccharides is a kind of water-soluble polysaccharide, by arabinose, glucose, gala This 6 kinds of monosaccharide components compositions of sugar, mannose, xylose and rhamnose, have physiological activity, can enhance nospecific immunity work( Can, disease resistance is improved, inhibits tumour growth and cell mutation.
Japanese tripterospermum herb, for cough due to wind-heat evil, jaundice, arthralgia pain due to rheumatism, roundworm disease, wind and heat dispersing, invigorating spleen to remove dampness.
Herba Solani Lyrati can be used as heat-clearing, removing toxic substances and wind-damp dispelling, to control lung cancer, gastrointestinal cancer.
A1, above-mentioned raw materials medicinal material is taken according to regulation percentage, and above-mentioned medicinal material is placed in the warm water of certain temperature It impregnates 30-50 minutes, the temperature of required warm water is 45 degree.
A2, the raw medicinal material that will impregnate completion in step a1 take out, and are placed on centrifuge dripping in cartridge filter, by it is above-mentioned from Raw material after heart drying is ground into powder.
A3, gained raw material powder addition suitable quantity of water in step a2 in marmite is fried boiling, then is decocted 10-20 minutes with small fire, Afterwards by the static placement of fried good above-mentioned raw material for a period of time, it is 30 minutes by the time of the static placement of raw material.
A4, the well-done raw material aqueous solution of decocting of gained in step a3 is poured into mixing and stirring tank and is sufficiently stirred so that It is fully being merged between various raw medicinal material powder, then the solution that above-mentioned stirring is completed is being filtered using 120 mesh screens, gone Except particle larger in solution, you can completion prepares Neulized inhalation liquid, then the above-mentioned Neulized inhalation liquid prepared is dispensed .
Preparation method embodiment one
A kind of preparation method for the Neulized inhalation liquid that peri-operation period uses is as follows:
A1, above-mentioned raw materials medicinal material is taken according to regulation percentage, and above-mentioned medicinal material is placed in the warm water of certain temperature It impregnates 30 minutes;
A2, the raw medicinal material that will impregnate completion in step a1 take out, and are placed on centrifuge dripping in cartridge filter, by it is above-mentioned from Raw material after heart drying is ground into powder;
A3, gained raw material powder in step a2 is added in into suitable quantity of water it is fried boiling in marmite, then 10 minutes are decocted with small fire, afterwards By fried good above-mentioned raw material static placement a period of time;
A4, the well-done raw material aqueous solution of decocting of gained in step a3 is poured into mixing and stirring tank and is sufficiently stirred so that It is fully being merged between various raw medicinal material powder, then the solution that above-mentioned stirring is completed is being filtered using 120 mesh screens, gone Except particle larger in solution, you can completion prepares Neulized inhalation liquid, then the above-mentioned Neulized inhalation liquid prepared is dispensed .
Preparation method embodiment two
A kind of preparation method for the Neulized inhalation liquid that peri-operation period uses is as follows:
A1, above-mentioned raw materials medicinal material is taken according to regulation percentage, and above-mentioned medicinal material is placed in the warm water of certain temperature It impregnates 40 minutes;
A2, the raw medicinal material that will impregnate completion in step a1 take out, and are placed on centrifuge dripping in cartridge filter, by it is above-mentioned from Raw material after heart drying is ground into powder;
A3, gained raw material powder in step a2 is added in into suitable quantity of water it is fried boiling in marmite, then 15 minutes are decocted with small fire, afterwards By fried good above-mentioned raw material static placement a period of time;
A4, the well-done raw material aqueous solution of decocting of gained in step a3 is poured into mixing and stirring tank and is sufficiently stirred so that It is fully being merged between various raw medicinal material powder, then the solution that above-mentioned stirring is completed is being filtered using 120 mesh screens, gone Except particle larger in solution, you can completion prepares Neulized inhalation liquid, then the above-mentioned Neulized inhalation liquid prepared is dispensed .
Preparation method embodiment three
A kind of preparation method for the Neulized inhalation liquid that peri-operation period uses is as follows:
A1, above-mentioned raw materials medicinal material is taken according to regulation percentage, and above-mentioned medicinal material is placed in the warm water of certain temperature It impregnates 50 minutes;
A2, the raw medicinal material that will impregnate completion in step a1 take out, and are placed on centrifuge dripping in cartridge filter, by it is above-mentioned from Raw material after heart drying is ground into powder;
A3, gained raw material powder in step a2 is added in into suitable quantity of water it is fried boiling in marmite, then 20 minutes are decocted with small fire, afterwards By fried good above-mentioned raw material static placement a period of time;
A4, the well-done raw material aqueous solution of decocting of gained in step a3 is poured into mixing and stirring tank and is sufficiently stirred so that It is fully being merged between various raw medicinal material powder, then the solution that above-mentioned stirring is completed is being filtered using 120 mesh screens, gone Except particle larger in solution, you can completion prepares Neulized inhalation liquid, then the above-mentioned Neulized inhalation liquid prepared is dispensed .
Clinical picture, case selection:In in June, 2014 in June, 2017 lung's related surgical Patients with 300 Cases, wherein man Property 170, women 130, in peri-operation period using the Neulized inhalation liquid for preparing of the present invention, the lung displayed after surgery For complication compared with the original clinical picture that the present invention is not used, the probability that pulmonary complication occur in these patients is reduced to original / 10th come, and the rehabilitation duration needed for patient also greatly shortens.
It can to sum up obtain, Neulized inhalation liquid which uses and preparation method thereof, by using japanese tripterospermum herb, Chinese trumpet creeper Grass, Sargent gloryvine, rheum officinale, saltcake, Medicated Leaven, moutan bark, the radix paeoniae rubrathe, Entada phaseoloides and the fruit of Chinese wolfberry, Sargent gloryvine have removing toxicity for eliminating carbuncles, and promoting blood circulation stops Bitterly, dispelling wind and eliminating dampness, disinsection efficiency cure mainly acute appendicitis, dysentery, breast pain, arthralgia pain due to rheumatism, abdominal pain due to enterositosis, Chinese herb rhubarb have attack it is stagnant, Clearing away damp-heat, purging intense heat, cool blood, dissolving stasis and removing toxic substances and other effects, japanese tripterospermum herb, for cough due to wind-heat evil, jaundice, arthralgia pain due to rheumatism, roundworm Disease, wind and heat dispersing, invigorating spleen to remove dampness, desinsection, Herba Solani Lyrati can be used as heat-clearing, removing toxic substances and wind-damp dispelling, to control lung cancer, gastrointestinal tract Cancer and being prepared by above-mentioned Chinese medicine material after Neulized inhalation liquid has more preferably for pulmonary surgery in the complication of peri-operation period Treatment conditioning effect, using the present invention Neulized inhalation liquid after can greatly reduce patient occur after surgery pulmonary infection, The probability that atelectasis, pulmonary edema, bronchitis and basic chronic pulmonary disease exacerbation happen, it is quick to be very beneficial for patient Rehabilitation.
It although an embodiment of the present invention has been shown and described, for the ordinary skill in the art, can be with Understanding without departing from the principles and spirit of the present invention can carry out these embodiments a variety of variations, modification, replace And modification, the scope of the present invention is defined by the appended.

Claims (3)

1. a kind of Neulized inhalation liquid that peri-operation period uses and preparation method thereof, it is characterised in that:Raw medicinal material includes swertia mileensis Grass 15%, Herba Solani Lyrati 15%, Sargent gloryvine 12%, rheum officinale 10%, saltcake 8%, Medicated Leaven 10%, moutan bark 4%, the excessively radix paeoniae rubrathe 6%, river Dragon 13% and the fruit of Chinese wolfberry 7%, the preparation method of the Neulized inhalation liquid are as follows:
A1, above-mentioned raw materials medicinal material is taken according to regulation percentage, and above-mentioned medicinal material is placed in the warm water of certain temperature and is impregnated 30-50 minutes;
A2, the raw medicinal material that completion is impregnated in step a1 is taken out, and is placed on centrifuge dripping in cartridge filter, by above-mentioned centrifugal drying Raw material after dry is ground into powder;
A3, gained raw material powder in step a2 is added in into suitable quantity of water it is fried boiling in marmite, then 10-20 minutes are decocted with small fire, afterwards By fried good above-mentioned raw material static placement a period of time;
A4, the well-done raw material aqueous solution of decocting of gained in step a3 is poured into mixing and stirring tank and is sufficiently stirred so that is various It is fully being merged between raw medicinal material powder, then the solution that above-mentioned stirring is completed is being filtered using 120 mesh screens, removal is molten Larger particle in liquid, you can completion prepares Neulized inhalation liquid, then the above-mentioned Neulized inhalation liquid prepared is dispensed.
2. Neulized inhalation liquid that a kind of peri-operation period according to claim 1 uses and preparation method thereof, it is characterised in that: In the step a1 and above-mentioned medicinal material is placed in the warm water of certain temperature and impregnated 30-50 minutes, the temperature of required warm water is 45 degree.
3. Neulized inhalation liquid that a kind of peri-operation period according to claim 1 uses and preparation method thereof, it is characterised in that: In the step a3 by the static placement of fried good above-mentioned raw material for a period of time, it is 30 points by the time of the static placement of raw material Clock.
CN201810184713.6A 2018-03-06 2018-03-06 Neulized inhalation liquid that a kind of peri-operation period uses and preparation method thereof Pending CN108096377A (en)

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Application publication date: 20180601