CN107184846A - It is a kind of to treat herbal composite of the proliferation of mammary gland and preparation method thereof - Google Patents
It is a kind of to treat herbal composite of the proliferation of mammary gland and preparation method thereof Download PDFInfo
- Publication number
- CN107184846A CN107184846A CN201710438009.4A CN201710438009A CN107184846A CN 107184846 A CN107184846 A CN 107184846A CN 201710438009 A CN201710438009 A CN 201710438009A CN 107184846 A CN107184846 A CN 107184846A
- Authority
- CN
- China
- Prior art keywords
- parts
- mammary gland
- proliferation
- root
- water
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/488—Pueraria (kudzu)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/36—Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/13—Coniferophyta (gymnosperms)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/13—Coniferophyta (gymnosperms)
- A61K36/15—Pinaceae (Pine family), e.g. pine or cedar
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/288—Taraxacum (dandelion)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/42—Cucurbitaceae (Cucumber family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/42—Cucurbitaceae (Cucumber family)
- A61K36/428—Trichosanthes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/58—Meliaceae (Chinaberry or Mahogany family), e.g. Azadirachta (neem)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
- A61K36/815—Lycium (desert-thorn)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0041—Mammary glands, e.g. breasts, udder; Intramammary administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/31—Extraction of the material involving untreated material, e.g. fruit juice or sap obtained from fresh plants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
Abstract
Present invention offer is a kind of to treat herbal composite of the proliferation of mammary gland and preparation method thereof, is made up of oral part and external application part, oral to be partly made up of the raw material of following parts by weight：The root of kudzu vine 10 20, pangolin 15 25, dandelion 8 17, Snakegourd Fruit 3 10, pollen pini 29, stone-like omphalia 16, Chinese torreyanut 16, bitter melon seed 15, red bean 28, black rice 16；External application part is made up of the raw material of following parts by weight：White fungus 39, Chinese toon 15, the fruit of Rangoon creeper 15, matrimony vine 38, wherein, the root of kudzu vine, pangolin are respectively through following pretreatment：The root of kudzu vine is soaked in black tea water, Chinese chive juice respectively, dried after cleaning；Pangolin dries drying in vegetable juice after soaking and washing.The herbal composite is by using oral part and external application part simultaneously, and synergy has excellent effect to the proliferation of mammary gland, and cure rate height can thoroughly solve the menstruation sexual cycle pain of breast, be that patient reduces the heavy burdens.
Description
Technical field
The invention belongs to technical field of traditional Chinese medicines, and in particular to a kind of herbal composite for treating the proliferation of mammary gland and its preparation
Method.
Background technology
The proliferation of mammary gland is most common one kind in mastosis, and its incidence of disease is in the trend risen year by year, and age of onset is also got over
Come lower.The pathogenic factor of the proliferation of mammary gland is that glandular lobule, tubule are highly expanded, and is changed in tumour sample, it is intracapsular full of serosity and
Courageous and upright liquid, the incidence of disease accounts for more than the 50% of women, and the disease is lobule of mammary gland physiological hyperplasia so that mammary gland normal configuration
Get muddled, belong to pathological proliferation.Clinically based on lump in breast, swollen breasts performance, but it is due to that mammary gland is female sharp
One of target organ of element effect, estrogen secretion is out of proportion, and long term can trigger this disease in breast tissue, so, mammary gland
Hyperplasia is also frequently accompanied by having obvious distending pain of the breast before physiology phase, and great burden is caused to patient.
Treatment typically to the proliferation of mammary gland, operative treatment, patient's receptance is relatively low；Drug therapy is divided into western medical treatment with
Cure and treat.Western medical treatment is generally hormone medicine, stosterone, progesterone etc., and influence of the long-term taking to liver kidney is serious, easily makes
Into iatrogenic injury；Chinese traditional treatment is generally oral drugs and externally used paste patch, although the proliferation of mammary gland is had certain effect,
But its treatment time is long；And after treatment, although the lump in breast of patient is obviously reduced, and distending pain sense usually also disappears, but
It is still to have obvious swollen breasts before menstrual period to occur, it is impossible to thoroughly solve the menstruation sexual cycle pain of breast, treatment is not
Thoroughly.
The content of the invention
For the defect of prior art, the present invention provides a kind of herbal composite for treating the proliferation of mammary gland, by oral portion
Divide and external application part composition, the effect for treating the proliferation of mammary gland is good, thorough treatment, can thoroughly solve the menstruation sexual cycle pain of breast
Bitterly.
A kind of herbal composite for treating the proliferation of mammary gland, is made up of oral part and external application part, wherein, it is described oral
Part is made up of the raw material of following parts by weight：10-20 parts of the root of kudzu vine, 15-25 parts of pangolin, 8-17 parts of dandelion, 3-10 parts of Snakegourd Fruit,
2-9 parts of pollen pini, 1-6 parts of stone-like omphalia, 1-6 parts of Chinese torreyanut, 1-5 parts of bitter melon seed, 2-8 parts of red bean, 1-6 parts of black rice；The external application portion
Divide and be made up of the raw material of following parts by weight：3-9 parts of white fungus, 1-5 parts of Chinese toon, 1-5 parts of the fruit of Rangoon creeper, 3-8 parts of matrimony vine,
Wherein, the root of kudzu vine passes through following pretreatment：The root of kudzu vine is immersed in 1-2h in black tea water at room temperature, in 2- after filtering
2h is soaked in 5 DEG C of Chinese chive juice, after taking-up, is cleaned up with water, then dries drying, the pretreated root of kudzu vine is obtained；
The pangolin passes through following pretreatment：Pangolin is soaked into 2-3h in vegetable juice, cleaned up with water, is then dried
Dry drying, obtains pretreated pangolin.
Preferably, the herbal composite of the treatment proliferation of mammary gland is made up of oral part and external application part, wherein, institute
Oral part is stated to be made up of the raw material of following parts by weight：13-17 parts of the root of kudzu vine, 17-23 parts of pangolin, 9-14 parts of dandelion, Snakegourd Fruit
7-9 parts, 3-6 parts of pollen pini, 1-4 parts of stone-like omphalia, 1-3 parts of Chinese torreyanut, 3 parts of bitter melon seed, 4-6 parts of red bean, 1-4 parts of black rice；It is described outer
It is made up of with part the raw material of following parts by weight：6-8 parts of white fungus, 3-5 parts of Chinese toon, 3 parts of the fruit of Rangoon creeper, 5-8 parts of matrimony vine.
The black tea water, which is prepared by the following method, to be obtained：Root of kudzu vine quality 0.1g black tea is weighed, is added to the water,
1h is heated at 100 DEG C, filters, takes filtrate to obtain the black tea water.
The Chinese chive juice, which is prepared by the following method, to be obtained：The leek of 0.2 times of root of kudzu vine quality is weighed, is added to the water,
Mashing, obtains the Chinese chive juice.
The vegetable juice, which is prepared by the following method, to be obtained：Compare balsam pear according to quality：Cucurbita pepo：Pangolin is 1:1:
5, balsam pear, cucurbita pepo are weighed, removes the peel, go after flesh, be added to the water, is beaten, obtains the vegetable juice.
The preparation method of the herbal composite of the treatment proliferation of mammary gland, is comprised the steps of：
（1）By the pretreated root of kudzu vine, pretreated pangolin, dandelion, Snakegourd Fruit, pollen pini, stone-like omphalia, Chinese torreyanut, bitter melon seed
Crush, add the water of oral 5 times of part material gross mass, plus 6-8h is decocted at 80-90 DEG C, filter, filter residue, filtrate are standby, so
Red bean and black rice are crushed afterwards, added in filter residue obtained above, the water of oral 5 times of part material gross mass, plus 80- is added
6-8h is decocted at 90 DEG C, is filtered, merges the filtrate obtained twice, that is, obtains described oral part；
（2）By Chinese toon at -30 ~ -20 DEG C vacuum freeze drying, ultramicro grinding, obtain Chinese toon powder；
（3）After the fruit of Rangoon creeper, matrimony vine are crushed, the water of 8 times of the fruit of Rangoon creeper is added, 6-8h is decocted at 70-80 DEG C, filtered, by filtrate
It is concentrated into the medicinal extract that relative density at 60 DEG C is 1.3-1.4；
（4）White fungus is crushed, the water of 4-6 times of white fungus quality is added, 2h soaks at room temperature in elder generation, it is ultrasonically treated after, in 90-100
3-4h is decocted at DEG C, tremella juice is obtained, by above-mentioned steps（2）Obtained Chinese toon powder, step（3）Obtained medicinal extract adds tremella juice
In, stirring, it is ultrasonically treated after, ultraviolet-sterilization obtains the external application part.
Step（2）600 mesh sieves are crossed after the ultramicro grinding.
Step（4）200 mesh sieves are crossed after the white fungus ultramicro grinding.
Step（4）The ultrasonically treated condition is the ultrasonically treated 30min under 100-200W.
The user of the herbal composite for the treatment proliferation of mammary gland that the present invention is provided：Use 2 times daily, oral part is every
Secondary 200mL, it is orally preceding to warm medicine；Simultaneously 10min is massaged after breast portion smears external application part, smearing.
The pharmacological action of various Chinese medicines in the present invention：
The root of kudzu vine：With turbidity removal of purging heat, effect damp and hot in vivo is removed, energy expelling pathogenic factors from muscles and skin is brought down a fever, and promoting eruption promotes the production of body fluid to quench thirst, Shengyang Zhixie；
Pangolin：With eliminating stasis and resolving masses, lower newborn effect of stimulating the menstrual flow, for Jing Bi wei lumps in the abdomen, alactation, carbuncle sore tumefacting virus；
Dandelion：It is clearing heat and detoxicating, dispersing swelling and dissipating binds, inducing diuresis for treating strangurtia；
Snakegourd Fruit：Clearing away heat and eliminating phlegm, relieving stuffiness of the chest by dispersing aggregation of pathogens, moisturize laxation, for cough with lung heat, chest impediment and cardialgia, accumulation of pathogens in chest feeling of fullness, acute mastitis, stool
It is constipated；
Pollen pini：Wind-dispelling, QI invigorating, hygroscopic, hemostasis；
Stone-like omphalia：Desinsection, disperse accumulations, it is known that stomachache, having indigestion；
Chinese torreyanut：Desinsection, disperse accumulations is moisturized；
Bitter melon seed：Containing abundant fat oil, the effect with QI invigorating；
Red bean：Li Shui disappears kind, removing toxic substances apocenosis, for oedema turgor, beriberoid pyretic arthralgia, carbuncle sore tumefacting virus；
Black rice：Play the role of in appetizing benefit, invigorating the spleen is invigorated blood circulation；
White fungus：Tonifying spleen appetizing, QI invigorating gut purge, nourishing Yin and moistening lung, can strengthen body immunity；
Chinese toon：Anti-inflammation hemostasia analgesic, promoting the circulation of qi regulating blood condition stomach invigorating；
The fruit of Rangoon creeper：Desinsection, disperse accumulations, invigorating the spleen, also with the effect for suppressing fungi；
Matrimony vine：Control the deficiency of Yin, quench one's thirst, can the foster kidney of tonifying liver；
Above-mentioned Chinese medicine complements each other, and is combined by oral part and the massage of external application part, with it is clearing heat and detoxicating, promoting blood circulation and removing blood stasis,
Reducing phlegm and resolving masses, the effect of dampness removing, there is preferable effect to the proliferation of mammary gland.
Advantages of the present invention：
The herbal composite for the treatment proliferation of mammary gland that the present invention is provided, it is right by simultaneously using oral part and external application part
The proliferation of mammary gland has excellent effect, and cure rate is high, can thoroughly solve the menstruation sexual cycle pain of breast, is that patient's mitigation is negative
Load.
Embodiment
Embodiment 1
1. a kind of herbal composite for treating the proliferation of mammary gland, is made up of oral part and external application part, wherein, it is described oral
Part is made up of the raw material of following parts by weight：10 parts of the root of kudzu vine, 15 parts of pangolin, 8 parts of dandelion, 3 parts of Snakegourd Fruit, 2 parts of pollen pini, thunder
6 parts of ball, 6 parts of Chinese torreyanut, 5 parts of bitter melon seed, 8 parts of red bean, 6 parts of black rice；The external application part is made up of the raw material of following parts by weight：
3 parts of white fungus, 1 part of Chinese toon, 5 parts of the fruit of Rangoon creeper, 8 parts of matrimony vine,
Wherein, the root of kudzu vine passes through following pretreatment：Root of kudzu vine quality 0.1g black tea is weighed, is added to the water, is added at 100 DEG C
Hot 1h, filtering, takes filtrate to obtain black tea water；The leek of 0.2 times of root of kudzu vine quality is weighed, is added to the water, is beaten, obtaining Chinese chive juice will
The root of kudzu vine is immersed in 1h in obtained black tea water at room temperature, and 2h is soaked in 2 DEG C of Chinese chive juice after filtering, clear with water after taking-up
Wash clean, then dries drying at 105 DEG C, obtains the pretreated root of kudzu vine；
The pangolin passes through following pretreatment：Compare balsam pear according to quality：Cucurbita pepo：Pangolin is 1:1:5, weigh balsam pear,
Cucurbita pepo, removes the peel, goes after flesh, be added to the water, mashing, obtains vegetable juice；Pangolin is soaked into 2h in vegetable juice, cleaned with water
Totally, drying then is dried at 105 DEG C, obtains pretreated pangolin.
2. treating the preparation method of the herbal composite of the proliferation of mammary gland, comprise the steps of：
（1）By the pretreated root of kudzu vine, pretreated pangolin, dandelion, Snakegourd Fruit, pollen pini, stone-like omphalia, Chinese torreyanut, bitter melon seed
Crush, add the water of oral 5 times of part material gross mass, plus 8h is decocted at 80 DEG C, filter, filter residue, filtrate are standby, then will be red
Red bean and black rice are crushed, and are added in filter residue obtained above, add the water of oral 5 times of part material gross mass, plus decocted at 80 DEG C
8h is boiled, is filtered, merges the filtrate obtained twice, that is, obtains described oral part；
（2）By Chinese toon at -30 DEG C vacuum freeze drying, ultramicro grinding, cross 600 mesh sieves, obtain Chinese toon powder；
（3）After the fruit of Rangoon creeper, matrimony vine are crushed, the water of 8 times of the fruit of Rangoon creeper is added, 8h is decocted at 70 DEG C, filtered, concentrate the filtrate to
To the medicinal extract that relative density at 60 DEG C is 1.31；
（4）White fungus is crushed, 200 mesh sieves are crossed, the water of 4 times of white fungus quality is added, first soaks 2h at room temperature, it is ultrasonic under 100W
Handle after 30min, decoct 4h at 90 DEG C, obtain tremella juice, by above-mentioned steps（2）Obtained Chinese toon powder, step（3）Obtain
Medicinal extract is added in tremella juice, stirring, the ultrasonically treated 30min under 100W, after, ultraviolet-sterilization obtains the external application part.
Embodiment 2
1. a kind of herbal composite for treating the proliferation of mammary gland, is made up of oral part and external application part, wherein, it is described oral
Part is made up of the raw material of following parts by weight：20 parts of the root of kudzu vine, 25 parts of pangolin, 17 parts of dandelion, 10 parts of Snakegourd Fruit, 9 parts of pollen pini,
1 part of stone-like omphalia, 1 part of Chinese torreyanut, 1 part of bitter melon seed, 2 parts of red bean, 1 part of black rice；The external application part by following parts by weight raw material group
Into：9 parts of white fungus, 5 parts of Chinese toon, 1 part of the fruit of Rangoon creeper, 3 parts of matrimony vine,
Wherein, the root of kudzu vine passes through following pretreatment：Root of kudzu vine quality 0.1g black tea is weighed, is added to the water, is added at 100 DEG C
Hot 1h, filtering, takes filtrate to obtain black tea water；The leek of 0.2 times of root of kudzu vine quality is weighed, is added to the water, is beaten, obtaining Chinese chive juice will
The root of kudzu vine is immersed in 2h in obtained black tea water at room temperature, and 2h is soaked in 5 DEG C of Chinese chive juice after filtering, clear with water after taking-up
Wash clean, then dries drying at 105 DEG C, obtains the pretreated root of kudzu vine；
The pangolin passes through following pretreatment：Compare balsam pear according to quality：Cucurbita pepo：Pangolin is 1:1:5, weigh balsam pear,
Cucurbita pepo, removes the peel, goes after flesh, be added to the water, mashing, obtains vegetable juice；Pangolin is soaked into 3h in vegetable juice, cleaned with water
Totally, drying then is dried at 105 DEG C, obtains pretreated pangolin.
2. treating the preparation method of the herbal composite of the proliferation of mammary gland, comprise the steps of：
（1）By the pretreated root of kudzu vine, pretreated pangolin, dandelion, Snakegourd Fruit, pollen pini, stone-like omphalia, Chinese torreyanut, bitter melon seed
Crush, add the water of oral 5 times of part material gross mass, plus 6h is decocted at 90 DEG C, filter, filter residue, filtrate are standby, then will be red
Red bean and black rice are crushed, and are added in filter residue obtained above, add the water of oral 5 times of part material gross mass, plus decocted at 90 DEG C
6h is boiled, is filtered, merges the filtrate obtained twice, that is, obtains described oral part；
（2）By Chinese toon at -20 DEG C vacuum freeze drying, ultramicro grinding, cross 600 mesh sieves, obtain Chinese toon powder；
（3）After the fruit of Rangoon creeper, matrimony vine are crushed, the water of 8 times of the fruit of Rangoon creeper is added, 6h is decocted at 80 DEG C, filtered, concentrate the filtrate to
To the medicinal extract that relative density at 60 DEG C is 1.35；
（4）White fungus is crushed, 200 mesh sieves are crossed, the water of 6 times of white fungus quality is added, first soaks 2h at room temperature, it is ultrasonic under 200W
Handle 30min, it is ultrasonically treated after, decoct 3h at 100 DEG C, obtain tremella juice, by above-mentioned steps（2）Obtained Chinese toon powder, step
Suddenly（3）Obtained medicinal extract is added in tremella juice, stirring, under 200W after ultrasonically treated 30min, ultraviolet-sterilization, that is, obtains described
External application part.
Embodiment 3
1. a kind of herbal composite for treating the proliferation of mammary gland, is made up of oral part and external application part, wherein, it is described oral
Part is made up of the raw material of following parts by weight：13 parts of the root of kudzu vine, 17 parts of pangolin, 9 parts of dandelion, 7 parts of Snakegourd Fruit, 3 parts of pollen pini, thunder
4 parts of ball, 3 parts of Chinese torreyanut, 3 parts of bitter melon seed, 6 parts of red bean, 4 parts of black rice；The external application part is made up of the raw material of following parts by weight：
6 parts of white fungus, 3 parts of Chinese toon, 3 parts of the fruit of Rangoon creeper, 5 parts of matrimony vine,
Wherein, the pretreatment be the same as Example 1 of the root of kudzu vine, pangolin.
The preparation method be the same as Example 1 of the herbal composite of the treatment proliferation of mammary gland.
Embodiment 4
1. a kind of herbal composite for treating the proliferation of mammary gland, is made up of oral part and external application part, wherein, it is described oral
Part is made up of the raw material of following parts by weight：17 parts of the root of kudzu vine, 23 parts of pangolin, 14 parts of dandelion, 9 parts of Snakegourd Fruit, 6 parts of pollen pini,
1 part of stone-like omphalia, 1 part of Chinese torreyanut, 3 parts of bitter melon seed, 4 parts of red bean, 1 part of black rice；The external application part by following parts by weight raw material group
Into：8 parts of white fungus, 5 parts of Chinese toon, 3 parts of the fruit of Rangoon creeper, 8 parts of matrimony vine,
Wherein, the pretreatment be the same as Example 1 of the root of kudzu vine, pangolin.
The preparation method be the same as Example 1 of the herbal composite of the treatment proliferation of mammary gland.
Embodiment 5
1. a kind of herbal composite for treating the proliferation of mammary gland, is made up of oral part and external application part, wherein, it is described oral
Part is made up of the raw material of following parts by weight：14 parts of the root of kudzu vine, 21 parts of pangolin, 13 parts of dandelion, 8 parts of Snakegourd Fruit, 4 parts of pollen pini,
2 parts of stone-like omphalia, 2 parts of Chinese torreyanut, 3 parts of bitter melon seed, 5 parts of red bean, 3 parts of black rice；The external application part by following parts by weight raw material group
Into：7 parts of white fungus, 4 parts of Chinese toon, 3 parts of the fruit of Rangoon creeper, 7 parts of matrimony vine,
Wherein, the root of kudzu vine passes through following pretreatment：Root of kudzu vine quality 0.1g black tea is weighed, is added to the water, is added at 100 DEG C
Hot 1h, filtering, takes filtrate to obtain black tea water；The leek of 0.2 times of root of kudzu vine quality is weighed, is added to the water, is beaten, obtaining Chinese chive juice will
The root of kudzu vine is immersed in 1.5h in obtained black tea water at room temperature, and 2h is soaked in 4 DEG C of Chinese chive juice after filtering, after taking-up, uses water
Clean up, then dry drying at 105 DEG C, obtain the pretreated root of kudzu vine；
The pangolin passes through following pretreatment：Compare balsam pear according to quality：Cucurbita pepo：Pangolin is 1:1:5, weigh balsam pear,
Cucurbita pepo, removes the peel, goes after flesh, be added to the water, mashing, obtains vegetable juice；Pangolin is soaked into 2.5h in vegetable juice, it is clear with water
Wash clean, then dries drying at 105 DEG C, obtains pretreated pangolin.
2. treating the preparation method of the herbal composite of the proliferation of mammary gland, comprise the steps of：
（1）By the pretreated root of kudzu vine, pretreated pangolin, dandelion, Snakegourd Fruit, pollen pini, stone-like omphalia, Chinese torreyanut, bitter melon seed
Crush, add the water of oral 5 times of part material gross mass, plus 7h is decocted at 85 DEG C, filter, filter residue, filtrate are standby, then will be red
Red bean and black rice are crushed, and are added in filter residue obtained above, add the water of oral 5 times of part material gross mass, plus decocted at 85 DEG C
7h is boiled, is filtered, merges the filtrate obtained twice, that is, obtains described oral part；
（2）By Chinese toon at -26 DEG C vacuum freeze drying, ultramicro grinding, cross 600 mesh sieves, obtain Chinese toon powder；
（3）After the fruit of Rangoon creeper, matrimony vine are crushed, the water of 8 times of the fruit of Rangoon creeper is added, 7h is decocted at 75 DEG C, filtered, concentrate the filtrate to
To the medicinal extract that relative density at 60 DEG C is 1.38；
（4）White fungus is crushed, 200 mesh sieves are crossed, the water of 5 times of white fungus quality is added, first soaks 2h at room temperature, it is ultrasonic under 150W
Handle after 30min, decoct 3.6h at 95 DEG C, obtain tremella juice, by above-mentioned steps（2）Obtained Chinese toon powder, step（3）Obtain
Medicinal extract add tremella juice in, stirring, the ultrasonically treated 30min under 150W, after, ultraviolet-sterilization obtains the external application part.
Comparative example 1（The root of kudzu vine and pangolin are without pretreatment, other be the same as Examples 5）
1. a kind of herbal composite for treating the proliferation of mammary gland, is made up of oral part and external application part, wherein, it is described oral
Part is made up of the raw material of following parts by weight：14 parts of the root of kudzu vine, 21 parts of pangolin, 13 parts of dandelion, 8 parts of Snakegourd Fruit, 4 parts of pollen pini,
2 parts of stone-like omphalia, 2 parts of Chinese torreyanut, 3 parts of bitter melon seed, 5 parts of red bean, 3 parts of black rice；The external application part by following parts by weight raw material group
Into：7 parts of white fungus, 4 parts of Chinese toon, 3 parts of the fruit of Rangoon creeper, 7 parts of matrimony vine.
2. treating the preparation method of the herbal composite of the proliferation of mammary gland, comprise the steps of：
（1）The root of kudzu vine, pangolin, dandelion, Snakegourd Fruit, pollen pini, stone-like omphalia, Chinese torreyanut, bitter melon seed are crushed, oral part material is added
7h is decocted at the water that 5 times of gross mass, plus 85 DEG C, is filtered, filter residue, filtrate are standby, is then crushed red bean and black rice, in addition
State in obtained filter residue, add the water of oral 5 times of part material gross mass, plus 7h is decocted at 85 DEG C, filter, merging is obtained twice
Filtrate, that is, obtain described oral part；
（2）By Chinese toon at -26 DEG C vacuum freeze drying, ultramicro grinding, cross 600 mesh sieves, obtain Chinese toon powder；
（3）After the fruit of Rangoon creeper, matrimony vine are crushed, the water of 8 times of the fruit of Rangoon creeper is added, 7h is decocted at 75 DEG C, filtered, concentrate the filtrate to
To the medicinal extract that relative density at 60 DEG C is 1.38；
（4）White fungus is crushed, 200 mesh sieves are crossed, the water of 5 times of white fungus quality is added, first soaks 2h at room temperature, it is ultrasonic under 150W
Handle after 30min, decoct 3.6h at 95 DEG C, obtain tremella juice, by above-mentioned steps（2）Obtained Chinese toon powder, step（3）Obtain
Medicinal extract add tremella juice in, stirring, the ultrasonically treated 30min under 150W, after, ultraviolet-sterilization obtains the external application part.
Comparative example 2（External application part is not contained, other be the same as Examples 5）
1. a kind of herbal composite for treating the proliferation of mammary gland, is made up of the raw material of following parts by weight：14 parts of the root of kudzu vine, pangolin
21 parts, 13 parts of dandelion, 8 parts of Snakegourd Fruit, 4 parts of pollen pini, 2 parts of stone-like omphalia, 2 parts of Chinese torreyanut, 3 parts of bitter melon seed, 5 parts of red bean, black rice 3
Part,
Wherein, the root of kudzu vine passes through following pretreatment：Root of kudzu vine quality 0.1g black tea is weighed, is added to the water, is added at 100 DEG C
Hot 1h, filtering, takes filtrate to obtain black tea water；The leek of 0.2 times of root of kudzu vine quality is weighed, is added to the water, is beaten, obtaining Chinese chive juice will
The root of kudzu vine is immersed in 1.5h in obtained black tea water at room temperature, and 2h is soaked in 4 DEG C of Chinese chive juice after filtering, after taking-up, uses water
Clean up, then dry drying at 105 DEG C, obtain the pretreated root of kudzu vine；
The pangolin passes through following pretreatment：Compare balsam pear according to quality：Cucurbita pepo：Pangolin is 1:1:5, weigh balsam pear,
Cucurbita pepo, removes the peel, goes after flesh, be added to the water, mashing, obtains vegetable juice；Pangolin is soaked into 2.5h in vegetable juice, it is clear with water
Wash clean, then dries drying at 105 DEG C, obtains pretreated pangolin.
2. treating the preparation method of the herbal composite of the proliferation of mammary gland, comprise the steps of：
（1）By the pretreated root of kudzu vine, pretreated pangolin, dandelion, Snakegourd Fruit, pollen pini, stone-like omphalia, Chinese torreyanut, bitter melon seed
Crush, add the water of oral 5 times of part material gross mass, plus 7h is decocted at 85 DEG C, filter, filter residue, filtrate are standby, then will be red
Red bean and black rice are crushed, and are added in filter residue obtained above, add the water of oral 5 times of part material gross mass, plus decocted at 85 DEG C
7h is boiled, is filtered, merges the filtrate obtained twice, you can.
Comparative example 3（The root of kudzu vine and pangolin do not contain external application part without pretreatment, other be the same as Examples 5）
1. a kind of herbal composite for treating the proliferation of mammary gland, is made up of the raw material of following parts by weight：14 parts of the root of kudzu vine, pangolin
21 parts, 13 parts of dandelion, 8 parts of Snakegourd Fruit, 4 parts of pollen pini, 2 parts of stone-like omphalia, 2 parts of Chinese torreyanut, 3 parts of bitter melon seed, 5 parts of red bean, black rice 3
Part.
2. treating the preparation method of the herbal composite of the proliferation of mammary gland, comprise the steps of：
（1）The root of kudzu vine, pangolin, dandelion, Snakegourd Fruit, pollen pini, stone-like omphalia, Chinese torreyanut, bitter melon seed are crushed, oral part material is added
7h is decocted at the water that 5 times of gross mass, plus 85 DEG C, is filtered, filter residue, filtrate are standby, is then crushed red bean and black rice, in addition
State in obtained filter residue, add the water of oral 5 times of part material gross mass, plus 7h is decocted at 85 DEG C, filter, merging is obtained twice
Filtrate, you can.
The pharmacological experiment of the one, proliferations of mammary gland
1. test medication and reagent
Chinese herbal medicine fluid prepared by embodiment 1-5.
Medicine A control groups：Prior art treats the Chinese medicine of mammary gland disease：According to made from the embodiments 1 of CN 102631453
Pasty state medicament.
Oestradiol benzoate and progesterone sterilizing oil solution be commercial goods.
1. test method：Wistar rats are taken, female unpregnancy, body weight 190-200g takes 90, is randomly divided into 9 groups, often
Group 10, respectively normal group, model control group, positive controls（RUKANG PIAN）, test group（Embodiment 1,2,5 and comparative example
1st, 2,3 Chinese medicine composition provided）.
In addition to normal group, every group with oestradiol benzoate 0.5mg/kg intramuscular injection 25 days, then is used instead progesterone 4mg/kg
Intramuscular injection prepares rat mammary gland model of hyperplasia for 5 days, and after success modeling, positive controls gavage RUKANG PIAN, test group is filled respectively
The Chinese medicine composition that stomach embodiment 1,2,5 and comparative example 1,2,3 are provided, metering is all 10mg/kg, model group and normal group gavage
The physiological saline of same dose, 1 group of breast portion in rat of embodiment 1,2,5 and comparative example smears the outer of the Chinese medicine composition
With part, other groups smear physiological saline.After administration 30 days, chest second is taken to breast, with vernier caliper measurement or so two
Breast diameter, height and papilla diameter；Again by Fuding in breast 10% formalin solution of immersion, specimens paraffin embedding slices haematine-
Eosin stains, Microscopic observation, the proliferation of mammary gland is divided into 4 grades according to pathological proliferation situation, and scores, and pathological grading and scoring rule are such as
Under：
The therapeutic action of rat mammary gland hyperplasia disease is shown in Table 1.
The treatment results of the rat mammary gland hyperplasia disease of table 1（）
Compared with model control group, * P ＜ 0.05.
The therapeutic action of Microscopic observation rat mammary gland hyperplasia disease, the results are shown in Table 2.
The therapeutic action of the Microscopic observation rat mammary gland hyperplasia disease of table 2（）
Compared with model control group, * P ＜ 0.05.
From Tables 1 and 2, the Chinese medicine composition for the treatment proliferation of mammary gland that the present invention is provided, to the proliferation of mammary gland with compared with
Good therapeutic effect.And when not using external application part, the root of kudzu vine and pangolin also without pretreatment, although to the proliferation of mammary gland
With certain effect, but its therapeutic effect is nothing like the Chinese medicine composition that the present invention is provided.
Two, model cases
1. Zhao, 43 years old, left breast outside upper quadrant had the lump of 3cm × 4cm sizes, and outer quadrant has 3cm × 2cm sizes
Lump；Quadrant has the lump of 2cm × 2cm sizes inside and outside right breast, and outer quadrant has the lump of 3cm × 3cm sizes, breast
Distending pain, especially substantially increases in menstrual period fore udder distending pain, after the Chinese medicine composition provided using the present invention 3 months, swells
Block is wholly absent, and swollen breasts disappear, and also do not have swollen breasts before official holiday, is continued to take this medicine and is consolidated 2 months, 2
Year does not recur.
2. Mr. Wang, 48 years old, double newborn pain, pain increase before official holiday, limitation of activity, infrared transillumination was shown inside and outside left breast
5cm × 4cm between outside upper quadrant in upper quadrant 6cm × 5cm size lumps, outer quadrant 3cm × 4cm strand lumps, right breast
Size lump, outer quadrant 2cm × 4cm lumps, after the Chinese medicine composition provided using the present invention 7 months, recovery from illness, lump is complete
Mistake is totally disappeared, swollen breasts disappear, also there are not swollen breasts before official holiday, do not recur within 1 year.
3. what certain, 38 years old, swollen breasts, Long-term taking medicine not positive effect, recurrent exerbation, the influence of official holiday fore udder distending pain
8cm × 8cm size lumps between quadrant inside and outside action, left breast, the outer quadrant 4cm × streak lumps of 6cm is using this
The Chinese medicine composition provided is invented after 6 months, lump is wholly absent, breast pain disappears, swollen breasts disappear, before official holiday
There are not swollen breasts, do not recur within 2 years.
Claims (9)
1. a kind of herbal composite for treating the proliferation of mammary gland, it is characterised in that：It is made up of oral part and external application part, its
In, the oral part is made up of the raw material of following parts by weight：10-20 parts of the root of kudzu vine, 15-25 parts of pangolin, 8-17 parts of dandelion,
3-10 parts of Snakegourd Fruit, 2-9 parts of pollen pini, 1-6 parts of stone-like omphalia, 1-6 parts of Chinese torreyanut, 1-5 parts of bitter melon seed, 2-8 parts of red bean, 1-6 parts of black rice；
The external application part is made up of the raw material of following parts by weight：3-9 parts of white fungus, 1-5 parts of Chinese toon, 1-5 parts of the fruit of Rangoon creeper, 3-8 parts of matrimony vine,
Wherein, the root of kudzu vine passes through following pretreatment：The root of kudzu vine is immersed in 1-2h in black tea water at room temperature, in 2- after filtering
2h is soaked in 5 DEG C of Chinese chive juice, after taking-up, is cleaned up with water, then dries drying, the pretreated root of kudzu vine is obtained；
The pangolin passes through following pretreatment：Pangolin is soaked into 2-3h in vegetable juice, cleaned up with water, is then dried
Dry drying, obtains pretreated pangolin.
2. the herbal composite of the proliferation of mammary gland is treated according to claim 1, it is characterised in that：The treatment proliferation of mammary gland
Herbal composite be made up of oral part and external application part, wherein, the oral part by following parts by weight raw material group
Into：13-17 parts of the root of kudzu vine, 17-23 parts of pangolin, 9-14 parts of dandelion, 7-9 parts of Snakegourd Fruit, 3-6 parts of pollen pini, 1-4 parts of stone-like omphalia, Chinese torreya
Sub- 1-3 parts, 3 parts of bitter melon seed, 4-6 parts of red bean, 1-4 parts of black rice；The external application part is made up of the raw material of following parts by weight：Silver
6-8 parts of ear, 3-5 parts of Chinese toon, 3 parts of the fruit of Rangoon creeper, 5-8 parts of matrimony vine.
3. the herbal composite of the treatment proliferation of mammary gland according to claim 1 or claim 2, it is characterised in that：The black tea water is
It is prepared by the following method what is obtained：Root of kudzu vine quality 0.1g black tea is weighed, is added to the water, 1h is heated at 100 DEG C, is filtered,
Filtrate is taken to obtain the black tea water.
4. the herbal composite of the treatment proliferation of mammary gland according to claim 1 or claim 2, it is characterised in that：The Chinese chive juice is
It is prepared by the following method what is obtained：The leek of 0.2 times of root of kudzu vine quality is weighed, is added to the water, is beaten, obtains the Chinese chive juice.
5. the herbal composite of the treatment proliferation of mammary gland according to claim 1 or claim 2, it is characterised in that：The vegetable juice is
It is prepared by the following method what is obtained：Compare balsam pear according to quality：Cucurbita pepo：Pangolin is 1:1:5, balsam pear, cucurbita pepo are weighed, is gone
Skin, go after flesh, be added to the water, be beaten, obtain the vegetable juice.
6. the preparation method of the herbal composite of the proliferation of mammary gland is treated described in claim 1, it is characterised in that：Include following step
Suddenly：
（1）By the pretreated root of kudzu vine, pretreated pangolin, dandelion, Snakegourd Fruit, pollen pini, stone-like omphalia, Chinese torreyanut, bitter melon seed
Crush, add the water of oral 5 times of part material gross mass, plus 6-8h is decocted at 80-90 DEG C, filter, filter residue, filtrate are standby, so
Red bean and black rice are crushed afterwards, added in filter residue obtained above, the water of oral 5 times of part material gross mass, plus 80- is added
6-8h is decocted at 90 DEG C, is filtered, merges the filtrate obtained twice, that is, obtains described oral part；
（2）By Chinese toon at -30 ~ -20 DEG C vacuum freeze drying, ultramicro grinding, obtain Chinese toon powder；
（3）After the fruit of Rangoon creeper, matrimony vine are crushed, the water of 8 times of the fruit of Rangoon creeper is added, 6-8h is decocted at 70-80 DEG C, filtered, by filtrate
It is concentrated into the medicinal extract that relative density at 60 DEG C is 1.3-1.4；
（4）White fungus is crushed, the water of 4-6 times of white fungus quality is added, 2h soaks at room temperature in elder generation, it is ultrasonically treated after, in 90-100
3-4h is decocted at DEG C, tremella juice is obtained, by above-mentioned steps（2）Obtained Chinese toon powder, step（3）Obtained medicinal extract adds tremella juice
In, stirring, it is ultrasonically treated after, ultraviolet-sterilization obtains the external application part.
7. the preparation method of the herbal composite of the proliferation of mammary gland is treated according to claim 6, it is characterised in that：
Step（2）600 mesh sieves are crossed after the ultramicro grinding.
8. the preparation method of the herbal composite of the proliferation of mammary gland is treated according to claim 6, it is characterised in that：
Step（4）200 mesh sieves are crossed after the white fungus ultramicro grinding.
9. the preparation method of the herbal composite of the proliferation of mammary gland is treated according to claim 6, it is characterised in that：
Step（4）The ultrasonically treated condition is the ultrasonically treated 30min under 100-200W.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710438009.4A CN107184846A (en) | 2017-06-12 | 2017-06-12 | It is a kind of to treat herbal composite of the proliferation of mammary gland and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710438009.4A CN107184846A (en) | 2017-06-12 | 2017-06-12 | It is a kind of to treat herbal composite of the proliferation of mammary gland and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107184846A true CN107184846A (en) | 2017-09-22 |
Family
ID=59877723
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710438009.4A Pending CN107184846A (en) | 2017-06-12 | 2017-06-12 | It is a kind of to treat herbal composite of the proliferation of mammary gland and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107184846A (en) |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106360820A (en) * | 2016-11-18 | 2017-02-01 | 陕西汉中秦辉生物医药科技有限公司 | Traditional-Chinese-medicine bra for preventing and treating breast diseases |
-
2017
- 2017-06-12 CN CN201710438009.4A patent/CN107184846A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106360820A (en) * | 2016-11-18 | 2017-02-01 | 陕西汉中秦辉生物医药科技有限公司 | Traditional-Chinese-medicine bra for preventing and treating breast diseases |
Non-Patent Citations (3)
| Title |
|---|
| 弭阳著: "《妇科病治验》", 31 March 2015, 山东大学出版社 * |
| 李玉芳等主编: "《乳腺增生症患者的家庭养护》", 31 October 2008, 科学技术文献出版社 * |
| 石原结实著，江勋源译: "《7天改善体温：跟疾病说再见》", 30 April 2012, 天津科学技术出版社 * |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN100577198C (en) | Medicine for curing cardio-cerebrovascular disease | |
| CN102579912B (en) | Chinese medicinal capsules special for treating acute mastitis and preparation method thereof | |
| CN100402081C (en) | Chinese patent medicine for treating gynaecologic disease and preparing method | |
| CN102648946A (en) | Warm compression thermal therapy liquid and preparation method thereof | |
| CN105435197A (en) | Pharmaceutical composition for treating chronic lymphocytic thyroiditis and preparation method thereof | |
| CN103536849A (en) | Drug for treating pulmonary embolism and preparation method thereof | |
| CN107753602A (en) | A kind of Chinese medicine composition for treating leukaemia and preparation method thereof | |
| CN107184846A (en) | It is a kind of to treat herbal composite of the proliferation of mammary gland and preparation method thereof | |
| CN104257917B (en) | A kind of precious jade medicine external preparation for preventing and treating woman puerperal fever and preparation method thereof | |
| CN107198727A (en) | A kind of pharmaceutical composition of beautifying face and moistering lotion promoting blood circulation for regulating menstruation and preparation method thereof | |
| CN107029041A (en) | A kind of radix glycyrrhizae strengthen immunity lavipeditum powder and preparation method thereof | |
| CN106109840A (en) | Radix Rehmanniae Pilulae for Improving Eyesight and preparation method thereof | |
| CN105381441A (en) | Traditional Chinese medicine capsule for preventing and treating cyesedema and preparation method of traditional Chinese medicine capsule | |
| CN102048145A (en) | Health food for treating hypertension in auxiliary mode and preparation method thereof | |
| CN105396038A (en) | A medicine for treating diabetes and a preparing method thereof | |
| CN105878571A (en) | Blood-circulation-invigorating healthy liquor | |
| CN104873858A (en) | Traditional Chinese medicine composition for treating functional dysmenorrheal | |
| CN104873748A (en) | Traditional Chinese medicine tea drink for relieving muscles, dissipating heat and preserving health and preparation method | |
| CN104997881A (en) | Decoction medicine capable of treating productive spondylitis and preparation method thereof | |
| CN104740396A (en) | Traditional Chinese medicine for treating kidney stones and preparation method of traditional Chinese medicine | |
| CN104257813A (en) | Traditional Chinese medicine composition for conditioning vital energy and blood and preparation method of traditional Chinese medicine composition | |
| CN111714566A (en) | Traditional Chinese medicine extract for tonifying liver and kidney and preventing miscarriage and preparation method thereof | |
| CN104147178A (en) | Internally-use traditional Chinese medicine pill for treating hysteromyoma and preparation method thereof | |
| CN108567908A (en) | Treat cirsoid Chinese medicine composition, external application Chinese medicine packet and its preparation method and application | |
| CN106963887A (en) | Treat Chinese medicine preparation of gout and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20170922 |