CN108079218A - Chinese medicine composition for treating skin stubborn dermatitis and preparation method thereof - Google Patents

Chinese medicine composition for treating skin stubborn dermatitis and preparation method thereof Download PDF

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Publication number
CN108079218A
CN108079218A CN201810106472.3A CN201810106472A CN108079218A CN 108079218 A CN108079218 A CN 108079218A CN 201810106472 A CN201810106472 A CN 201810106472A CN 108079218 A CN108079218 A CN 108079218A
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chinese medicine
medicine composition
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幸永明
潘胜果
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Chongqing Yuelong Biological Pharmaceutical Co Ltd
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Chongqing Yuelong Biological Pharmaceutical Co Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/718—Coptis (goldthread)
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    • A61K31/12—Ketones
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    • A61K31/125—Camphor; Nuclear substituted derivatives thereof
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    • A61K36/18—Magnoliophyta (angiosperms)
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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    • A61K36/185—Magnoliopsida (dicotyledons)
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/29—Berberidaceae (Barberry family), e.g. barberry, cohosh or mayapple
    • A61K36/296—Epimedium
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
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    • A61K36/88—Liliopsida (monocotyledons)
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Abstract

The present invention relates to a kind of for treating Chinese medicine composition of skin stubborn dermatitis and preparation method thereof.The raw material of Chinese medicine composition includes：20~30 parts by weight of the coptis, 10~15 parts by weight of the root bark of tree peony, public yellow 20~25 parts by weight of Pu, 10~15 parts by weight of reed root, 10~20 parts by weight of Radix Ophiopogonis, 20~25 parts by weight of amethyst, 20~30 parts by weight of camphor, 30~40 parts by weight of wild chrysanthemum, 20~40 parts by weight of garden euphorbia herb, 15~20 parts by weight of Asiatic plantain, 10~15 parts by weight of frangipanis, 10~20 parts by weight of beggar-ticks, 10~15 parts by weight of climbing groundsel, white thorn 15~20 parts by weight of amaranth, 10~20 parts by weight of 5~10 parts by weight of the radix paeoniae rubrathe and HERBA EPIMEDII.Chinese medicine composition of the present invention has excellent clearing heat and detoxicating, dehumidifying inducing diaphoresis, promoting blood circulation putrefaction-removing granulation-promoting and other effects, can effectively remove internal blood poison, eliminate itch, inhibit all kinds of tinea bacterium, effect a radical cure skin tinea, and safe without toxic side effect.

Description

Chinese medicine composition for treating skin stubborn dermatitis and preparation method thereof
Technical field
The present invention relates to field of Chinese herbal medicine technology, and in particular to it is a kind of for treat skin stubborn dermatitis Chinese medicine composition and its Preparation method.
Background technology
Skin tinea belongs to cutaneous diseases, and because wind-heat damp evil attacks skin, Yu Jiufeng Shengs then turn to worm, glue Beancurd sheet skin Cheng Ji, constantly itching pain is ceaselessly.Common ringworm has psoriasis, red lichen, tinea of feet and hands, mange, ringworm of the body etc., often with slowly Dermatoses, pruritus dermatopathy, fungal dermatoses, suppurative dermatosis and chronic eczema, being chapped from the cold property eczema, intractable are wet The mixing of the multiple dermatosis such as disease, seborrhea occurs.
For medicine mostly based on Dakin solution, conventional medicament has liquor carbonis detergens, coal-tar ointment, zinc oxide at present Finish, zinc ointment, pine evaporate paste, pine evaporates oily ointment, benzoic acid paint, benzoic acid ointment, ichthyol ointment, carbamide ointment Deng；Oral traditional Chinese medicine compound preparation has potassium arsenite solution etc..Since skin tinea comes from tinea bacterium, tinea strain class is various, multiply with Internal blood is supported, and makes blood turbid toxic, is sticked at vitro skin into disease, is made human body epidermis is rotten to burst.However, above-mentioned Chinese medicine preparation is to disappear Based on scorching, sterilization, effect is chiefly used in vitro skin affected part, but the work(without radical cure is multiplied to internal blood poison and tinea bacterium, to skin tinea Disease is palliative, recur into persistent ailment more.
Based on this, study a kind of new, safe without toxic side effect and treatment that can effectively, safe or alleviation skin are stupid The drug of tinea has very important significance.
The content of the invention
For in the prior art the defects of, the present invention is intended to provide it is a kind of for treat skin stubborn dermatitis Chinese medicine composition and Its preparation method.Chinese medicine composition provided by the invention has the work(such as excellent clearing heat and detoxicating, dehumidifying inducing diaphoresis, promoting blood circulation putrefaction-removing granulation-promoting Effect can effectively remove internal blood poison, eliminate itch, inhibit all kinds of tinea bacterium, effect a radical cure skin tinea, and safe and non-toxic secondary work With；In addition, Chinese medicine composition provided by the invention is easy to use, cost is relatively low, has good commercial promise.
For this purpose, the present invention provides following technical solution：
In a first aspect, the present invention provides a kind of Chinese medicine composition for being used to treat skin stubborn dermatitis, raw material components are by weight Meter, including：Public yellow 20~25 parts by weight of 20~30 parts by weight of the coptis, 10~15 parts by weight of the root bark of tree peony, Pu, 10~15 weight of reed root It is part, 10~20 parts by weight of Radix Ophiopogonis, 20~25 parts by weight of amethyst, 20~30 parts by weight of camphor, 30~40 parts by weight of wild chrysanthemum, big 20~40 parts by weight of hairy euphorbia, 15~20 parts by weight of Asiatic plantain, 10~15 parts by weight of frangipanis, 10~20 parts by weight of beggar-ticks, 10~20 parts by weight of 5~10 parts by weight of the radix paeoniae rubrathe and HERBA EPIMEDII.
Preferably, raw material components further include：15~20 parts by weight of 10~15 parts by weight of climbing groundsel and Bai Ci amaranths.
Preferably, which is made of following raw material components：30 parts by weight of the coptis, 10 parts by weight of the root bark of tree peony, Pu Gong Yellow 25 parts by weight, 10 parts by weight of reed root, 20 parts by weight of Radix Ophiopogonis, 20 parts by weight of amethyst, 30 parts by weight of camphor, 30 weight of wild chrysanthemum Part, 40 parts by weight of garden euphorbia herb, 15 parts by weight of Asiatic plantain, 20 parts by weight of white thorn amaranth, 10 parts by weight of frangipanis, 15 weight of climbing groundsel Part, 10 parts by weight of 10 parts by weight of beggar-ticks, 10 parts by weight of the radix paeoniae rubrathe and HERBA EPIMEDII.
Preferably, which is made of following raw material components：20 parts by weight of the coptis, 15 parts by weight of the root bark of tree peony, Pu Gong Yellow 20 parts by weight, 15 parts by weight of reed root, 10 parts by weight of Radix Ophiopogonis, 25 parts by weight of amethyst, 20 parts by weight of camphor, 40 weight of wild chrysanthemum Part, 20 parts by weight of garden euphorbia herb, 20 parts by weight of Asiatic plantain, 15 parts by weight of white thorn amaranth, 15 parts by weight of frangipanis, 10 weight of climbing groundsel Part, 20 parts by weight of 20 parts by weight of beggar-ticks, 5 parts by weight of the radix paeoniae rubrathe and HERBA EPIMEDII.
Second aspect, the present invention provide a kind of preparation method of Chinese medicine composition, comprise the following steps：It is weighed according to proportioning Each raw material components are crushed after being cleaned, extracted afterwards with water, and filtrate is collected in filtering；Filtrate is condensed into 70 DEG C of phases To the medicinal extract that density is 1.05~1.20, Chinese medicine composition is obtained.
Preferably, refluxing extraction is extracted as, and the temperature of refluxing extraction is 80 DEG C~90 DEG C, extraction time is 1~3 time, The time extracted every time is 60min~100min.
Preferably, each raw material components are crushed to 30~100 mesh.
It should be noted that Chinese medicine composition prepared by the above method can be further prepared into pharmaceutically connecing as needed The dosage form received.In addition, fall within protection scope of the present invention by drug made of active ingredient of above-mentioned Chinese medicine composition.Pass through It by above-mentioned Chinese medicine composition, is prepared after directly preparing or adding in pharmaceutically acceptable auxiliary material, can be made into and any pharmaceutically may be used The dosage form of receiving.Include by taking external preparation as an example：Solution, patch, vina, tincture, gelling agent, liniment, aerosol, spraying Agent, ointment, suppository and plastics.The drug of above-mentioned various dosage forms can be prepared according to the conventional method of pharmaceutical field. In clinical practice, the application method for the Chinese medicine composition that the present invention is prepared is preferably：Chinese medicine composition is applied to illness It is general to cover affected skin scope at skin, it smears 2 times daily；Smearing number of days can be adjusted according to the state of an illness.
The third aspect, Chinese medicine composition provided by the invention is in treatment skin stubborn dermatitis drug or medicated premix is prepared Using.
The above technical solution of the present invention has the following advantages over the prior art：
(1) applicant has found by numerous studies：Chinese medicine composition provided by the invention have it is excellent it is clearing heat and detoxicating, remove Wet inducing diaphoresis, promoting blood circulation putrefaction-removing granulation-promoting and other effects, can effectively remove internal blood poison, eliminate itch, inhibit all kinds of tinea bacterium, effect a radical cure skin Skin ringworm, and safe without toxic side effect；In addition, Chinese medicine composition provided by the invention is easy to use, cost is relatively low, has fine Commercial promise.
(2) preparation method provided by the invention is used, the same of each bulk pharmaceutical chemicals active ingredient can retained to greatest extent When, the active ingredient in each raw medicinal material can be fully released, so that the Chinese medicine composition being finally prepared is not Only there is good drug effect, and be easy to absorb, and then be rapidly achieved the purpose for improving skin stubborn dermatitis.
The additional aspect and advantage of the present invention will be set forth in part in the description, and will partly become from the following description It obtains substantially or is recognized by the practice of the present invention.
Specific embodiment
The embodiment of technical solution of the present invention will be described in detail below.Following embodiment is only used for clearer Illustrate technical scheme, therefore be only used as example, and be not intended to limit the protection scope of the present invention and limit the scope of the invention.
Experimental method in following embodiments is conventional method unless otherwise specified.
Test material used, is to be commercially available from conventional reagent shop unless otherwise specified in following embodiments.
Quantitative test in following embodiment, is respectively provided with three repeated experiments, and data are the average value of three repeated experiments Or mean+SD.
The coptis used in following embodiments, the root bark of tree peony, reed root, Radix Ophiopogonis, amethyst, camphor, wild chrysanthemum, big fly at Pu Gonghuang Raise grass, Asiatic plantain, frangipanis, beggar-ticks, climbing groundsel, pierce amaranth in vain, the radix paeoniae rubrathe and HERBA EPIMEDII meet Chinese Pharmacopoeia (version in 2016) Pertinent regulations under each medicinal material item of one text.Before feeding intake, by identification, ingredients material object is consistent with title, and quality meets Standard.
The present invention provides a kind of Chinese medicine composition for being used to treat skin stubborn dermatitis, which is characterized in that raw material components are by weight Part meter, including：Public yellow 20~25 parts by weight of 20~30 parts by weight of the coptis, 10~15 parts by weight of the root bark of tree peony, Pu, 10~15 weight of reed root It is part, 10~20 parts by weight of Radix Ophiopogonis, 20~25 parts by weight of amethyst, 20~30 parts by weight of camphor, 30~40 parts by weight of wild chrysanthemum, big 20~40 parts by weight of hairy euphorbia, 15~20 parts by weight of Asiatic plantain, 10~15 parts by weight of frangipanis, 10~20 parts by weight of beggar-ticks, 10~20 parts by weight of 5~10 parts by weight of the radix paeoniae rubrathe and HERBA EPIMEDII.Wherein, raw material components preferably further include：10~15 weight of climbing groundsel Part and white thorn 15~20 parts by weight of amaranth.
In addition, for the Chinese medicine composition of the present invention, the present invention specially devises preparation method, comprises the following steps：
Each raw material components are weighed according to proportioning, 30~100 mesh are crushed to after being cleaned, are extracted afterwards with water, mistake Filtrate is collected in filter；Relative density is 1.05~1.20 medicinal extract when filtrate is condensed into 70 DEG C, obtains Chinese medicine composition.Wherein, It is extracted as refluxing extraction, and the temperature of refluxing extraction is 80 DEG C~90 DEG C, extraction time is 1~3 time, and the time extracted every time is 60min~100min.
It illustrates With reference to embodiment：
Embodiment one
The present embodiment provides a kind of for treating the Chinese medicine composition of skin stubborn dermatitis, it is prepared by following raw material components： Public yellow 25 parts by weight of 30 parts by weight of the coptis, 10 parts by weight of the root bark of tree peony, Pu, 10 parts by weight of reed root, 20 parts by weight of Radix Ophiopogonis, 20 weight of amethyst Measure part, 30 parts by weight of camphor, 30 parts by weight of wild chrysanthemum, 40 parts by weight of garden euphorbia herb, 15 parts by weight of Asiatic plantain, 10 weight of frangipanis Part, 10 parts by weight of 10 parts by weight of beggar-ticks, 10 parts by weight of the radix paeoniae rubrathe and HERBA EPIMEDII.
By above-mentioned raw materials component, preparation method using the present invention prepares Chinese medicine composition：
Each raw material components are weighed according to proportioning, 100 mesh are crushed to after being cleaned, are extracted afterwards with water, are filtered, are received Collect filtrate；Relative density is 1.05 medicinal extract when filtrate is condensed into 70 DEG C, obtains Chinese medicine composition.Wherein, it is extracted as flowing back Extraction, and the temperature of refluxing extraction is 90 DEG C, extraction time is 2 times, and the time extracted every time is 100min.
Embodiment two
The present embodiment provides a kind of for treating the Chinese medicine composition of skin stubborn dermatitis, it is prepared by following raw material components： Public yellow 25 parts by weight of 30 parts by weight of the coptis, 10 parts by weight of the root bark of tree peony, Pu, 10 parts by weight of reed root, 20 parts by weight of Radix Ophiopogonis, 20 weight of amethyst Measure part, 30 parts by weight of camphor, 30 parts by weight of wild chrysanthemum, 40 parts by weight of garden euphorbia herb, 15 parts by weight of Asiatic plantain, 10 weight of frangipanis Part, 10 parts by weight of 10 parts by weight of beggar-ticks, 10 parts by weight of the radix paeoniae rubrathe and HERBA EPIMEDII.
By above-mentioned raw materials component, preparation method using the present invention prepares Chinese medicine composition：
Each raw material components are weighed according to proportioning, 30 mesh are crushed to after being cleaned, are extracted afterwards with water, are filtered, are received Collect filtrate；Relative density is 1.20 medicinal extract when filtrate is condensed into 70 DEG C, obtains Chinese medicine composition.Wherein, it is extracted as flowing back Extraction, and the temperature of refluxing extraction is 80 DEG C, extraction time is 3 times, and the time extracted every time is 60min.
Embodiment three
The present embodiment provides a kind of for treating the Chinese medicine composition of skin stubborn dermatitis, it is prepared by following raw material components： Public yellow 25 parts by weight of 30 parts by weight of the coptis, 10 parts by weight of the root bark of tree peony, Pu, 10 parts by weight of reed root, 20 parts by weight of Radix Ophiopogonis, 20 weight of amethyst Measure part, 30 parts by weight of camphor, 30 parts by weight of wild chrysanthemum, 40 parts by weight of garden euphorbia herb, 15 parts by weight of Asiatic plantain, white thorn 20 weight of amaranth Part, 10 parts by weight of frangipanis, 15 parts by weight of climbing groundsel, 10 parts by weight of 10 parts by weight of beggar-ticks, 10 parts by weight of the radix paeoniae rubrathe and HERBA EPIMEDII.
By above-mentioned raw materials component, preparation method using the present invention prepares Chinese medicine composition：
Each raw material components are weighed according to proportioning, 100 mesh are crushed to after being cleaned, are extracted afterwards with water, are filtered, are received Collect filtrate；Relative density is 1.05 medicinal extract when filtrate is condensed into 70 DEG C, obtains Chinese medicine composition.Wherein, it is extracted as flowing back Extraction, and the temperature of refluxing extraction is 90 DEG C, extraction time is 2 times, and the time extracted every time is 100min.
Example IV
The present embodiment provides a kind of for treating the Chinese medicine composition of skin stubborn dermatitis, it is prepared by following raw material components： Public yellow 25 parts by weight of 30 parts by weight of the coptis, 10 parts by weight of the root bark of tree peony, Pu, 10 parts by weight of reed root, 20 parts by weight of Radix Ophiopogonis, 20 weight of amethyst Measure part, 30 parts by weight of camphor, 30 parts by weight of wild chrysanthemum, 40 parts by weight of garden euphorbia herb, 15 parts by weight of Asiatic plantain, white thorn 20 weight of amaranth Part, 10 parts by weight of frangipanis, 15 parts by weight of climbing groundsel, 10 parts by weight of 10 parts by weight of beggar-ticks, 10 parts by weight of the radix paeoniae rubrathe and HERBA EPIMEDII.
By above-mentioned raw materials component, preparation method using the present invention prepares Chinese medicine composition：
Each raw material components are weighed according to proportioning, 30 mesh are crushed to after being cleaned, are extracted afterwards with water, are filtered, are received Collect filtrate；Relative density is 1.20 medicinal extract when filtrate is condensed into 70 DEG C, obtains Chinese medicine composition.Wherein, it is extracted as flowing back Extraction, and the temperature of refluxing extraction is 80 DEG C, extraction time is 3 times, and the time extracted every time is 60min.
In addition, the effect of in order to preferably evaluate each embodiment, carry out following experiment：
First, toxicity test
The little white rabbit 40 (each 20 of male and female) that weight is selected to be 2~3kg, is divided into 4 groups, each 5 of every group of male and female.By each little Bai Rabbit back shaving, every shaving area are 5cm × 8cm, and then in back shaving area coating, it is about 2.0g/ to apply dose, respectively The Chinese medicine composition of the treatment Pi Fu Wan Ringworm that the embodiment of the present invention one to example IV is prepared is smeared in skin of back, continuously Coating 20 days.When during coating and 1 week after drug withdrawal, white mouse growth conditions and activity and diet, identification hematology, blood biochemical are observed , organ tissue structure and routine urinalysis etc..It turns out that the health existence of all little white rabbits, without any side effects；Dissection Observe blood picture, liver function, each organs and tissues state, the indifference compared with normal little white rabbit.It is demonstrated experimentally that provided by the invention control The Chinese medicine composition for treating Pi Fu Wan Ringworm has no toxic side effect, and can use safely.
2nd, clinical test
Collect skin stubborn dermatitis patient 400.Specifically, patient is divided into 4 groups, every group 100, by first group to the 4th Group smears the embodiment of the present invention one to the Chinese medicine composition 3 weeks of example IV respectively, 2 times a day；Curative effect is observed afterwards, and is measured Each patient skin stubborn dermatitis Cure, it is specific as shown in table 1.
Curative effect is judged according to country《Clinical diagnosis is according to healing improvement standard》It determines：(1) fully recover：Symptom all disappears, And 3 years or more without recurrence；(2) improve：Cardinal symptom disappears, and is observed continuously 2 years or more without recurrence；(3) it is invalid：Symptom is without bright It is aobvious to improve.
1 each embodiment patient skin stubborn dermatitis clinical symptoms of table improve situation statistical form
Case number of cases/name Effective/name Improvement/name Invalid/name Total effective rate/%
Embodiment one 100 78 22 0 100
Embodiment two 100 80 19 1 99
Embodiment three 100 88 12 0 100
Example IV 100 89 11 0 100
Certainly, except the situation that embodiment one to example IV is enumerated, the species and weight percent of other raw material components, Condition and parameter in preparation process etc. are also possible.
Chinese medicine composition provided by the invention has excellent clearing heat and detoxicating, dehumidifying inducing diaphoresis, promoting blood circulation putrefaction-removing granulation-promoting and other effects, It can effectively remove internal blood poison, eliminate itch, inhibit all kinds of tinea bacterium, effect a radical cure skin tinea, and safe without toxic side effect；This Outside, Chinese medicine composition provided by the invention is easy to use, and cost is relatively low, has good commercial promise.
In the description of this specification, it is to be understood that reference term " one embodiment ", " some embodiments ", " show The description of example ", " specific example " or " some examples " etc. mean to combine the specific features of the embodiment or example description, structure, Material or feature are contained at least one embodiment of the present invention or example.In the present specification, above-mentioned term is shown The statement of meaning property is necessarily directed to identical embodiment or example.Moreover, specific features, structure, material or the spy of description Point may be combined in any suitable manner in any one or more of the embodiments or examples.In addition, without conflicting with each other, Those skilled in the art can be by the different embodiments described in this specification or example and different embodiments or exemplary Feature is combined and combines.
Although the embodiment of the present invention has been shown and described above, it is to be understood that above-described embodiment is example Property, it is impossible to limitation of the present invention is interpreted as, those of ordinary skill in the art within the scope of the invention can be to above-mentioned Embodiment is changed, changes, replacing and modification.

Claims (8)

  1. It is 1. a kind of for treating the Chinese medicine composition of skin stubborn dermatitis, which is characterized in that raw material components by weight, including：
    Public yellow 20~25 parts by weight of 20~30 parts by weight of the coptis, 10~15 parts by weight of the root bark of tree peony, Pu, 10~15 parts by weight of reed root, wheat 10~20 parts by weight of winter, 20~25 parts by weight of amethyst, 30~40 parts by weight of wild chrysanthemum, are flown upward greatly at 20~30 parts by weight of camphor Careless 20~40 parts by weight, 15~20 parts by weight of Asiatic plantain, 10~15 parts by weight of frangipanis, 10~20 parts by weight of beggar-ticks, the radix paeoniae rubrathe 5 10~20 parts by weight of~10 parts by weight and HERBA EPIMEDII.
  2. 2. the Chinese medicine composition according to claim 1 for being used to treat skin stubborn dermatitis, it is characterised in that：
    Raw material components further include：15~20 parts by weight of 10~15 parts by weight of climbing groundsel and Bai Ci amaranths.
  3. 3. the Chinese medicine composition according to claim 2 for being used to treat skin stubborn dermatitis, which is characterized in that by following raw material groups Divide and be made：
    Public yellow 25 parts by weight of 30 parts by weight of the coptis, 10 parts by weight of the root bark of tree peony, Pu, 10 parts by weight of reed root, 20 parts by weight of Radix Ophiopogonis, amethyst 20 parts by weight, 30 parts by weight of camphor, 30 parts by weight of wild chrysanthemum, 40 parts by weight of garden euphorbia herb, 15 parts by weight of Asiatic plantain, white thorn amaranth 20 Parts by weight, 10 parts by weight of frangipanis, 15 parts by weight of climbing groundsel, 10 weight of 10 parts by weight of beggar-ticks, 10 parts by weight of the radix paeoniae rubrathe and HERBA EPIMEDII Measure part.
  4. 4. the Chinese medicine composition according to claim 2 for being used to treat skin stubborn dermatitis, which is characterized in that by following raw material groups Divide and be made：
    Public yellow 20 parts by weight of 20 parts by weight of the coptis, 15 parts by weight of the root bark of tree peony, Pu, 15 parts by weight of reed root, 10 parts by weight of Radix Ophiopogonis, amethyst 25 parts by weight, 20 parts by weight of camphor, 40 parts by weight of wild chrysanthemum, 20 parts by weight of garden euphorbia herb, 20 parts by weight of Asiatic plantain, white thorn amaranth 15 Parts by weight, 15 parts by weight of frangipanis, 10 parts by weight of climbing groundsel, 20 weight of 20 parts by weight of beggar-ticks, 5 parts by weight of the radix paeoniae rubrathe and HERBA EPIMEDII Part.
  5. 5. the preparation method of Claims 1 to 4 any one of them Chinese medicine composition, which is characterized in that comprise the following steps：
    Each raw material components are weighed according to proportioning, crushes after being cleaned, is extracted afterwards with water, are filtered, collect filtrate；By institute The medicinal extract that relative density when filtrate is condensed into 70 DEG C is 1.05~1.20 is stated, obtains the Chinese medicine composition.
  6. 6. the preparation method of the Chinese medicine composition described in claim 5, it is characterised in that：
    It is described to be extracted as refluxing extraction, and the temperature of the refluxing extraction is 80 DEG C~90 DEG C, extraction time is 1~3 time, every time The time of extraction is 60min~100min.
  7. 7. the preparation method of the Chinese medicine composition described in claim 5, it is characterised in that：
    Each raw material components are crushed to 30~100 mesh.
  8. 8. Claims 1 to 4 any one of them Chinese medicine composition is preparing treatment skin stubborn dermatitis drug and/or medicated premix In application.
CN201810106472.3A 2018-02-02 2018-02-02 Chinese medicine composition for treating skin stubborn dermatitis and preparation method thereof Pending CN108079218A (en)

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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104162052A (en) * 2013-01-17 2014-11-26 刘凤华 Preparation method of traditional Chinese medicine composition for treating psoriasis
CN106692830A (en) * 2017-03-03 2017-05-24 贵州都匀市剑江药业有限公司 Traditional Chinese medicine composition for treating skin stubborn dermatitis and preparation method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104162052A (en) * 2013-01-17 2014-11-26 刘凤华 Preparation method of traditional Chinese medicine composition for treating psoriasis
CN106692830A (en) * 2017-03-03 2017-05-24 贵州都匀市剑江药业有限公司 Traditional Chinese medicine composition for treating skin stubborn dermatitis and preparation method thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
顾润环: "顾维超辨治疑难病症举隅", 《疑难病杂志》 *

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Application publication date: 20180529