CN108066621A - A kind of dendrobium officinale American ginseng particle and preparation method thereof - Google Patents
A kind of dendrobium officinale American ginseng particle and preparation method thereof Download PDFInfo
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- CN108066621A CN108066621A CN201711468024.XA CN201711468024A CN108066621A CN 108066621 A CN108066621 A CN 108066621A CN 201711468024 A CN201711468024 A CN 201711468024A CN 108066621 A CN108066621 A CN 108066621A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/898—Orchidaceae (Orchid family)
- A61K36/8984—Dendrobium
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
- A61K36/815—Lycium (desert-thorn)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
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- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
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- Animal Behavior & Ethology (AREA)
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Abstract
The invention discloses a kind of dendrobium officinale American ginseng particle and preparation method thereof, which is made of following weight composition:30 50 parts of 200 300 parts of dendrobium candidum, 150 200 parts of American Ginseng, 1 10 parts of matrimony vine, 10 18 parts of Radix Paeoniae Alba, 35 parts of Radix Angelicae Sinensis, 90 125 parts of dextrin and D-sorbite.Dendrobium officinale American ginseng particle of the present invention is equipped with dextrin, D-sorbite as auxiliary material, can effectively improve dendrobium polysaccharide content, have effects that strengthen immunity using dendrobium candidum and American Ginseng as primary raw material；The pharmacological property of plurality of Chinese can be mixed into simultaneously among the stem of noble dendrobium, improve the drug effect of product.
Description
Technical field
The present invention relates to a kind of dendrobium officinale American ginseng particles and preparation method thereof.
Background technology
Dendrobium candidum is a kind of rare Chinese medicine, and in the giant panda among the people for being known as medicine circle, Shanghai and Zhejiang are crossed at me
It is especially welcome Deng some coastal cities.Contained polysaccharide is mutated with anti-cell in dendrobium candidum, and the clear internal aging casualties is thin
The effect of born of the same parents can stablize the physiological status of body, also have and increase the immune cell functions such as T lymphocytes and natural killer cells
Remarkable effect, have to cancer patient and dramatically increase the most use of T cell immune function, the macrophage of activation can direct killing
Tumour cell, moreover it is possible to discharge some cell silver to play biological function, many adjustment effects are played to immune system.
The making of existing dendrobium candidum product be all by simply adding water to cook, although make it is simple, but
This decoction method can not extract higher dendrobium polysaccharide content well, while current dendrobium candidum, American Ginseng are deposited
In inconvenient eating, active ingredient is absorbed by the body the problems such as utilization rate is low, and effect is not notable, if therefore can make full use of iron sheet stone
The medicinal efficacy of dry measure used in former times, American Ginseng, develops a kind of health product, undoubtedly has huge market value.
The content of the invention
The technical problems to be solved by the invention are to provide a kind of making simply, and convenient to take, absorption of human body is good, drug effect profit
High with rate, dendrobium polysaccharide content is high, can improve the dendrobium officinale American ginseng particle of immunity.
To solve the above problems, the present invention is achieved through the following technical solutions：A kind of dendrobium candidum American Ginseng
Grain, the dendrobium officinale American ginseng particle are made of following weight composition:200-300 parts of dendrobium candidum, American Ginseng
30-50 parts of 150-200 parts, 1-10 parts of matrimony vine, 10-18 parts of Radix Paeoniae Alba, 3-5 parts of Radix Angelicae Sinensis, 90-125 parts of dextrin and D-sorbite.
Another technical problem to be solved by this invention is to provide a kind of preparation method of dendrobium officinale American ginseng particle,
The present invention is achieved through the following technical solutions：The preparation process of the dendrobium officinale American ginseng particle is such as
Under：
1) 200-300 parts of dendrobium candidum of extraction by weight ratio is ground into particle, adds water to cook four times, decocts 2- every time
3 it is small when；
2) 1-10 parts of matrimony vine, Radix Paeoniae Alba 10-18 are handed in extraction respectively during the dendrobium candidum of step 1 adds water to cook for four times
Part, 3-5 parts of Radix Angelicae Sinensis, 90-125 parts of dextrin are added；
3) 150-200 parts of American Ginseng of extraction by weight ratio is ground into particle, adds water to cook twice, decocts 2-3 every time
Hour；
4) the dendrobium candidum mixed liquor after extraction step 2 decocts carries out separating twice, and addition clear water stirs after the completion of crushing
It mixes；
5) liquid that extraction step 4 stirs evenly carries out cooling precipitation；
6) the American Ginseng liquid after extraction step 3 decocts is filtered, and is precipitated, dry；
7) clear liquid after extraction step 5 precipitates is mixed with the American ginseng extract of step 6, while adds D-sorbite 30-
It 50 parts, concentrates as paste；
8) particle is made with conventional method in the compound of extraction step 7.
Further, every 100 grams of the capsule finished product of the making is containing 15 grams of Thick many candies, containing 1 gram of total saposins.
The advantageous effect of dendrobium officinale American ginseng particle of the present invention is：The dendrobium officinale American ginseng particle is with dendrobium candidum
It is primary raw material with American Ginseng, is equipped with dextrin, D-sorbite as auxiliary material, can effectively improve dendrobium polysaccharide content, there is enhancing
The effect of immunity；The pharmacological property of plurality of Chinese can be mixed into simultaneously among the stem of noble dendrobium, improve the drug effect of product.
Specific embodiment
Following embodiment is not limited to the scope of the present invention for illustrating the present invention.
Embodiment 1
A kind of dendrobium officinale American ginseng particle of the present invention, which is by following weight
Composition forms:200 parts of dendrobium candidum, 150 parts of American Ginseng, 1 part of matrimony vine, 10 parts of Radix Paeoniae Alba, 3 parts of Radix Angelicae Sinensis, 90 parts of dextrin and sorbose
30 parts of alcohol.
The preparation process of the dendrobium officinale American ginseng particle is as follows：
1) 200 parts of dendrobium candidum of extraction by weight ratio is ground into particle, adds water to cook four times, and it is small to decoct 2-3 every time
When；
2) 1 part of matrimony vine, 10 parts of Radix Paeoniae Alba, Radix Angelicae Sinensis 3 are handed in extraction respectively during the dendrobium candidum of step 1 adds water to cook for four times
Part, 90 parts of dextrin are added；
3) 150 parts of American Ginseng of extraction by weight ratio is ground into particle, adds water to cook twice, when decoction 2-3 is small every time；
4) the dendrobium candidum mixed liquor after extraction step 2 decocts carries out separating twice, and addition clear water stirs after the completion of crushing
It mixes；
5) liquid that extraction step 4 stirs evenly carries out cooling precipitation；
6) the American Ginseng liquid after extraction step 3 decocts is filtered, and is precipitated, dry；
7) clear liquid after extraction step 5 precipitates is mixed with the American ginseng extract of step 6, while adds D-sorbite 30
Part, it concentrates as paste；
8) particle is made with conventional method in the compound of extraction step 7.
Every 100 grams of the capsule finished product of the making is containing 15 grams of Thick many candies, containing 1 gram of total saposins.
Embodiment 2
Its difference from Example 1 is that the dendrobium officinale American ginseng particle is by following weight composition group
Into:300 parts of dendrobium candidum, 200 parts of American Ginseng, 10 parts of matrimony vine, 18 parts of Radix Paeoniae Alba, 5 parts of Radix Angelicae Sinensis, 125 parts of dextrin and D-sorbite 50
Part.
Embodiment 3
Its difference from Example 1 is that the dendrobium officinale American ginseng particle is by following weight composition group
Into:250 parts of dendrobium candidum, 180 parts of American Ginseng, 5 parts of matrimony vine, 14 parts of Radix Paeoniae Alba, 4 parts of Radix Angelicae Sinensis, 110 parts of dextrin and D-sorbite 40
Part.
Embodiment 4
Its difference from Example 1 is that the dendrobium officinale American ginseng particle is by following weight composition group
Into:213 parts of dendrobium candidum, 161 parts of American Ginseng, 3 parts of matrimony vine, 12 parts of Radix Paeoniae Alba, 3.3 parts of Radix Angelicae Sinensis, 94 parts of dextrin and D-sorbite 36
Part.
Embodiment 5
Its difference from Example 1 is that the dendrobium officinale American ginseng particle is by following weight composition group
Into:289 parts of dendrobium candidum, 178 parts of American Ginseng, 8 parts of matrimony vine, 17 parts of Radix Paeoniae Alba, 4.7 parts of Radix Angelicae Sinensis, 121 parts of dextrin and D-sorbite 44
Part.
Embodiment 6
Its difference from Example 1 is that the dendrobium officinale American ginseng particle is by following weight composition group
Into:233 parts of dendrobium candidum, 166 parts of American Ginseng, 6 parts of matrimony vine, 16 parts of Radix Paeoniae Alba, 3.6 parts of Radix Angelicae Sinensis, 99 parts of dextrin and D-sorbite 42
Part.
Embodiment 7
Its difference from Example 1 is that the dendrobium officinale American ginseng particle is by following weight composition group
Into:277 parts of dendrobium candidum, 171 parts of American Ginseng, 7 parts of matrimony vine, 17 parts of Radix Paeoniae Alba, 4.4 parts of Radix Angelicae Sinensis, 117 parts of dextrin and D-sorbite 33
Part.
Embodiment 8
Its difference from Example 1 is that the dendrobium officinale American ginseng particle is by following weight composition group
Into:255 parts of dendrobium candidum, 155 parts of American Ginseng, 5.5 parts of matrimony vine, 15 parts of Radix Paeoniae Alba, 3.5 parts of Radix Angelicae Sinensis, 115 parts of dextrin and D-sorbite
40 parts.
The present invention is not limited to above-mentioned preferred forms, anyone the present invention enlightenment under draw other it is any with
Product as the present invention is same or similar, is within the scope of the present invention.
Claims (3)
1. a kind of dendrobium officinale American ginseng particle, it is characterised in that：The dendrobium officinale American ginseng particle is matched somebody with somebody by following parts by weight
It is formed than composition:200-300 parts of dendrobium candidum, 150-200 parts of American Ginseng, 1-10 parts of matrimony vine, 10-18 parts of Radix Paeoniae Alba, Radix Angelicae Sinensis 3-5
30-50 parts of part, 90-125 parts of dextrin and D-sorbite.
2. a kind of preparation method for preparing dendrobium officinale American ginseng particle described in claim 1, it is characterised in that：This method bag
Include following steps：
1) 200-300 parts of dendrobium candidum of extraction by weight ratio is ground into particle, adds water to cook four times, and it is small to decoct 2-3 every time
When；
2) during the dendrobium candidum of step 1 adds water to cook for four times respectively extraction hand over 1-10 parts of matrimony vine, 10-18 parts of Radix Paeoniae Alba, when
Return 3-5 parts, 90-125 parts of dextrin is added；
3) 150-200 parts of American Ginseng of extraction by weight ratio is ground into particle, adds water to cook twice, when decoction 2-3 is small every time；
4) the dendrobium candidum mixed liquor after extraction step 2 decocts carries out separating twice, addition clear water stirring after the completion of crushing；
5) liquid that extraction step 4 stirs evenly carries out cooling precipitation；
6) the American Ginseng liquid after extraction step 3 decocts is filtered, and is precipitated, dry；
7) clear liquid after extraction step 5 precipitates is mixed with the American ginseng extract of step 6, while adds 30-50 parts of D-sorbite,
It concentrates as paste；
8) particle is made with conventional method in the compound of extraction step 7.
3. the preparation method of dendrobium officinale American ginseng particle according to claim 2, it is characterised in that：The glue of the making
Every 100 grams of capsule finished product is containing 15 grams of Thick many candies, containing 1 gram of total saposins.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711468024.XA CN108066621A (en) | 2017-12-29 | 2017-12-29 | A kind of dendrobium officinale American ginseng particle and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201711468024.XA CN108066621A (en) | 2017-12-29 | 2017-12-29 | A kind of dendrobium officinale American ginseng particle and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108066621A true CN108066621A (en) | 2018-05-25 |
Family
ID=62155843
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201711468024.XA Pending CN108066621A (en) | 2017-12-29 | 2017-12-29 | A kind of dendrobium officinale American ginseng particle and preparation method thereof |
Country Status (1)
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| CN (1) | CN108066621A (en) |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20120315289A1 (en) * | 2011-06-13 | 2012-12-13 | Hsin-Sheng Tsay | Non-polysaccharide constituent of genus Dendrobium, usage for the non-polysaccharide constituent of genus Dendrobium and extracting method thereof |
| CN103007052A (en) * | 2012-12-14 | 2013-04-03 | 上海绿谷制药有限公司 | Compound dendrobium extract composition capable of delaying senility |
-
2017
- 2017-12-29 CN CN201711468024.XA patent/CN108066621A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20120315289A1 (en) * | 2011-06-13 | 2012-12-13 | Hsin-Sheng Tsay | Non-polysaccharide constituent of genus Dendrobium, usage for the non-polysaccharide constituent of genus Dendrobium and extracting method thereof |
| CN103007052A (en) * | 2012-12-14 | 2013-04-03 | 上海绿谷制药有限公司 | Compound dendrobium extract composition capable of delaying senility |
Non-Patent Citations (1)
| Title |
|---|
| 王增等: "HPLC测定铁皮石斛饮料中人参皂苷Rb1的含量", 《中国现代应用药学》 * |
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