CN108065369A - 一种蝙蝠蛾被毛孢菌粉保健品 - Google Patents
一种蝙蝠蛾被毛孢菌粉保健品 Download PDFInfo
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- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
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- A61K36/06—Fungi, e.g. yeasts
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/41—Crassulaceae (Stonecrop family)
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
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- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
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- A—HUMAN NECESSITIES
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Abstract
本发明属于保健食品领域，具体涉及一种蝙蝠蛾被毛孢菌粉保健品。该制剂按重量计，由以下原料制成：蝙蝠蛾被毛孢菌粉0.1～0.3g，黄芪0.05～0.3g，红景天0.01‑0～2g。本发明提供的保健品可调节人体免疫，改善肺部呼吸肾脾功能，调节机体阴阳平衡，改善亚健康状态。具有提高免疫力、抗缺氧的功效，用于高原代偿性缺氧、免疫力低下等症的辅助治疗。
Description
技术领域
本发明属于保健食品领域，具体涉及一种蝙蝠蛾被毛孢菌粉保健品。
背景技术
随着人们生活、工作节奏的加快，工作压力增大，同时废气、垃圾、工业、噪音及射线等污染，严重损害人们的生存环境，导致身体处于亚健康的人群大量增加，免疫力低下的人群显著增加。缺氧是我国北方常见的冬春季疾病，主要表现气喘、胸闷、呼吸不畅、嘴脸青紫等。这些疾病常常影响着人们的生活与健康。因此改善亚健康状态、提高免疫力，改善尤其是冬春季节的缺氧及呼吸系统障碍状况就显得意义重大。
发明内容
本发明提供一种具有提高免疫力、抗缺氧抗疲劳的功用，用于高原代偿性缺氧等症的辅助治疗的蝙蝠蛾被毛孢菌粉保健品。
为实现上述目的，本发明采用的技术方案为：
一种蝙蝠蛾被毛孢菌粉保健品，按重量计，包括以下原料：蝙蝠蛾被毛孢菌粉0.1～0.3g。
优选地，蝙蝠蛾被毛孢菌粉0.1～0.3g，黄芪0.05～0.3g，红景天0.01～0.2g。
优选地，蝙蝠蛾被毛孢菌粉0.2～0.3g，黄芪0.1～0.3g，红景天0.02～0.2g。
优选地，蝙蝠蛾被毛孢菌粉0.2～0.3g，黄芪0.1～0.2g，红景天0.03～0.1g。
优选地，蝙蝠蛾被毛孢菌粉0.25g，黄芪0.15g，红景天0.05g。
本发明还有关于一种蝙蝠蛾被毛孢菌粉保健品的制备方法。
一种蝙蝠蛾被毛孢菌粉保健品的制备方法，包括以下步骤：
(1)按照原料重量比例称取中药材，净选；
(2)将上述净选后原料混合粉碎成粉末，过40目筛，得混合粉末；
(3)将步骤(2)所得的混合粉末作为合适的保健品。
或：
(1)按照原料药重量比例称取原料，净选；
(2)将上述净选后药材混匀，粉碎成粗粉，加6-10倍量水，浸泡1-4小时，煎煮1-3次，每次1-3小时，过滤，合并滤液，减压浓缩至45℃-60℃，测相对密度为1.20-1.25，呈浸膏状，加乙醇静置、醇沉、过滤，滤液减压回收乙醇至无醇味，减压浓缩至60℃热测时相对密度1.00-1.10的流浸膏；
(3)将步骤(2)所得的流浸膏制备成药学上可接受的保健品。
本发明中，所述保健品为胶囊剂、片剂、颗粒剂、散剂或口服液，为使上述剂型能够实现，可以在制备这些剂型时加入法规范围内可接受的辅料，例如：填充剂、崩解剂、润滑剂、助悬剂、粘合剂、甜味剂、矫味剂、防腐剂等，填充剂包括：淀粉、预胶化淀粉、乳糖、甘露醇、甲壳素、微晶纤维素、蔗糖等，崩解剂包括：淀粉、预胶化淀粉、微晶纤维素、羧甲基淀粉钠、交联聚乙烯吡咯烷酮、低取代羟丙纤维素、交联羧甲基纤维素钠等，润滑剂包括：硬脂酸镁、十二烷基硫酸钠、滑石粉、二氧化硅等，助悬剂包括：聚乙烯吡咯烷酮、微晶纤维素、蔗糖、琼脂、羟丙基甲基纤维素等，粘合剂包括，淀粉浆、聚乙烯吡咯烷酮、羟丙基甲基纤维素等，甜味剂包括：糖精钠、阿斯帕坦、蔗糖、甜蜜素、甘草次酸等，矫味剂包括：甜味剂及各种香精，防腐剂包括：尼泊金类、苯甲酸、苯甲酸钠、山梨酸及其盐类、苯扎溴铵、醋酸氯乙定、桉叶油等。
本发明通过对人体的津液、气血进行补养和调理，以科学生产工艺，提供一种能有效改善亚健康状态、改善上述症状的蝙蝠蛾被毛孢菌粉保健品。黄芪性温，蝙蝠蛾被毛孢性平，红景天性平，组方中以主入肺肾滋阴的蝙蝠蛾被毛孢菌粉为主，主入心肺强化气血的红景天为辅，强化对心肺功能的效用，黄芪辅佐理气固本，强于补气，助气运行，整体性平微温，适合于各种体虚证免疫力低下的人群使用。
本组方性味比较温和，主要功能是平补阴阳，兼顾五脏，突出对呼吸系统及机体免疫功能的调节，适用于多种亚健康人群及体质虚弱、抵抗力低下人群，强化对代偿性高原缺氧及疲劳恢复、老年性呼吸循环系统调理、呼吸功能减退衰弱等人群的使用，有助于机体气血津液运行及阴阳平衡的恢复，同时还包括了许多其他综合性作用。
具体实施方式
以下实施例原料均购自药材市场并经过鉴定。
实施例1
蝙蝠蛾被毛孢菌粉保健品的制备：
取原料药：发酵蝙蝠蛾被毛孢菌粉0.25g，黄芪0.15g，红景天0.05g。
(1)按照原料重量比例称取中药材，净选；
(2)将上述净选后药材混合粉碎成粉末，过40目筛，得混合粉末；
(3)将步骤(2)所得的混合粉末作为活性成分，与适量淀粉混匀，过筛后充分混匀，分装入胶囊中即得，每粒0.2g或每粒0.4g。
实施例2
蝙蝠蛾被毛孢菌粉保健品的制备：
取原料药：蝙蝠被毛孢菌粉0.3g，黄芪0.3g，红景天0.2g。
(1)按照原料重量比例称取中药材，净选；
(2)将上述净选后药材混匀，粉碎成粗粉，加9倍量水，浸泡2小时，煎煮2次，每次2小时，过滤，合并滤液，减压浓缩至60℃热测时相对密度为1.20-1.25的浸膏，加乙醇静置、醇沉、过滤，滤液减压回收乙醇至无醇味，减压浓缩至60℃热测时相对密度1.00-1.10的流浸膏；
(3)将步骤(2)所得的流浸膏用适量蒸馏水稀释，过滤，稀释液含生药量为20％，加入单糖浆，山梨酸钾，制得。
实施例3
蝙蝠蛾被毛孢菌粉保健品的制备：
取原料药：蝙蝠被毛孢菌粉10g，黄芪5g，红景天1g。
(1)按照原料重量比例称取中药材，净选；
(2)将上述净选后药材混合粉碎成粉末，过40目筛，得混合粉末；
(3)将步骤(2)所得的混合粉末作为活性成分，与适量淀粉、滑石粉和硬脂酸镁，混匀，过筛后直接压片即得。每片0.4g。
实施例4
典型病例：
1、王XX等114例志愿者(年龄55-65岁)中，随机分为3组，A组38例为健康者；B组38例身体虚弱，免疫力低下，经常感冒，平均每三个月均感冒一次；C组38例同样体质虚弱，免疫力低下，经常感冒，平均每三个月均感冒一次。A组和B组均每天早晚饭前服用实施例1制备的胶囊各4粒，C组每天早晚饭前服用无活性成分，仅以淀粉装入的胶囊各4粒。连续服用一年，其它生活习惯与平时相同。经随访调查，结果：A组中36人精力充沛，2人感冒一次；B组中34人未感冒，2人感冒一次，2人感冒两次，且均精力日渐充沛；C组则未见健康状况的改善，仅8人未感冒，8人感冒一次，15人感冒两次，7人感冒3次或以上。
临床研究表明，本发明制剂具有明显的改善亚健康状况，提高人体免疫力的效果。
2、选择自愿接受治疗的冬春季代偿性高原缺氧、老年性呼吸循环系统障碍、等症240例，男120例，女120例，年龄45-56岁，平均50岁。患者均长期反复胸闷、气喘、感染，每年发作至少三月，并持续2年以上，且排除心肺疾病，即其临床症状、体征检查均符合代偿性高原缺氧、老年性呼吸循环系统障碍。随机分为A组、B组、C组、D组、E组、F组，每组40例；各组患者年龄症状构成无显著差异，具有可比性(P>0.05)。
A、B、C、D、E为治疗组，基础治疗一致，F组为对照组，不服药。A组用本发明实施例3，每日三次，一次1片。B组用头孢氨苄，每次0.25g，每日4次。C组采用与实施例3同样的方法制备的仅以蝙蝠蛾被毛孢菌粉为原料制备的片剂，每日三次，一次1片。D组采用与实施例3同样的方法制备的仅以黄芪为原料制备的片剂，每日三次，一次1片。E组采用与实施例3同样的方法制备的仅以红景天为原料制备的片剂，每日三次，一次1片。30日为一疗程。
诊断标准：痊愈：症状、体征检查和X线胸片均已恢复正常，痰菌培养阴性；显效：症状、体征检查恢复正常，痰菌培养转阴，X线胸片炎性病变基本吸收；进步：症状和体征有所减轻，X线胸片炎性病变有部分吸收；无效：病情无明显改善或有所加重。
结果如下：
而在本组方中蝙蝠蛾被毛孢益肺滋肾，平喘止嗽，调理肺功能；黄芪补气固本，提升元气，改善气虚证候；红景天益气活血，通脉平喘，改善肺功能。
而由以上结果可以看出，虽然蝙蝠蛾被毛孢、黄芪和红景天分别均能够起到一定的改善呼吸系统功能，抗缺氧的作用，但是其组合物产生了明显的协同增效作用，本发明提供的蝙蝠蛾被毛孢菌粉保健品能够有效改善冬春季老年代偿性缺氧，改善老年性呼吸循环系统障碍的作用。
Claims (9)
1.一种蝙蝠蛾被毛孢菌粉保健品，其特征在于：按重量计，包括以下原料：蝙蝠蛾被毛孢菌粉0.1～0.3g。
2.一种蝙蝠蛾被毛孢菌粉保健品，其特征在于：按重量计，由以下原料制成：蝙蝠蛾被毛孢菌粉0.1～0.3g，黄芪0.05～0.3g，红景天0.01～0.2g。
3.如权利要求2所述的保健品，其特征在于：按重量计，由以下原料制成：蝙蝠蛾被毛孢菌粉0.2～0.3g，黄芪0.1～0.3g，红景天0.02～0.2g。
4.如权利要求2所述的保健品，其特征在于：按重量计，由以下原料制成：蝙蝠蛾被毛孢菌粉0.2～0.3g，黄芪0.1～0.2g，红景天0.03～0.1g。
5.如权利要求2所述的保健品，其特征在于：按重量计，由以下原料制成：蝙蝠蛾被毛孢菌粉0.25g，黄芪0.15g，红景天0.05g。
6.如权利要求1～5任一项所述的保健品，其特征在于：所述制剂剂型为胶囊剂、片剂、颗粒剂、散剂或口服液。
7.如权利要求1～5任一项所述的保健品的制备方法，其特征在于：包括以下步骤：
(1)按照原料重量比例称取药材，净选；
(2)将上述净选后药材混合粉碎成粉末，过40目筛，得混合粉末；
(3)将步骤(2)所得的混合粉末作为活性成分制备成保健品。
8.如权利要求1～5任一项所述的保健品的制备方法，其特征在于：包括以下步骤：
(1)按照原材料重量比例称取原料，净选；
(2)将上述净选后原料混匀，粉碎成粗粉，加6～10倍量水，浸泡1～4小时，煎煮1～3次，每次1～3小时，过滤，合并滤液，45℃～60℃减压浓缩至相对密度为1.20～1.25，呈浸膏状，加乙醇静置、醇沉、过滤，滤液减压回收乙醇至无醇味，60℃减压浓缩至相对密度1.00～1.10的流浸膏；
(3)将步骤(2)所得的流浸膏制备成保健品。
9.如权利要求1～5任一项所述的保健品在制备改善亚健康状况、调节免疫力或抗缺氧中的应用。
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