CN108042428A - A kind of shallow composition of the drift containing tea bran and its application - Google Patents

A kind of shallow composition of the drift containing tea bran and its application Download PDF

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Publication number
CN108042428A
CN108042428A CN201711449814.3A CN201711449814A CN108042428A CN 108042428 A CN108042428 A CN 108042428A CN 201711449814 A CN201711449814 A CN 201711449814A CN 108042428 A CN108042428 A CN 108042428A
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Prior art keywords
shallow
composition
drift
basifier
dose
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CN201711449814.3A
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CN108042428B (en
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肖瑞光
方如惠
许桂萍
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ZHAOQING DICAI DAILY CHEMICAL SCIENCE AND TECHNOLOGY Co Ltd
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ZHAOQING DICAI DAILY CHEMICAL SCIENCE AND TECHNOLOGY Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • A61Q5/002Preparations for repairing the hair, e.g. hair cure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • A61Q5/08Preparations for bleaching the hair
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • A61Q5/10Preparations for permanently dyeing the hair
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q5/00Preparations for care of the hair
    • A61Q5/12Preparations containing hair conditioners
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2800/00Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
    • A61K2800/40Chemical, physico-chemical or functional or structural properties of particular ingredients
    • A61K2800/42Colour properties
    • A61K2800/43Pigments; Dyes
    • A61K2800/432Direct dyes

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Cosmetics (AREA)

Abstract

The present invention relates to a kind of shallow composition of drift containing tea bran and its applications.The mass fraction of the shallow composition of drift including tea bran in first dose and second dose at least containing oxidant, described first dose at least containing basifier and tea bran is 1 ~ 60%, and the mass fraction of first dose of moderate stimulation basifier is not higher than 2.0%.The shallow composition of drift provided by the invention has added with tea bran and preferably floats shallow effect, irritation is low, small to hair damage, while damaged hair can be repaired, and increases hair compliance;The shallow composition of drift added with colouring component, can catch gorgeous color on hair, and hair is submissive after dye, and good hand touch is glossy, and resistance to shampoo washability is excellent, have larger application value.

Description

A kind of shallow composition of the drift containing tea bran and its application
Technical field
The invention belongs to cosmetic fields, and in particular, to a kind of shallow composition of the drift containing tea bran and its application.
Background technology
Hair dyeing is all considered as the symbol of fashion all the time.Hair color is more shallow after dye, more gorgeous, more fashion, then is more disappeared Expense person's particularly young consumers are liked.Oxidation-reduction type hair dye is since color colour system scope that it is generated is wide, resistance to shampoo The superperformances such as washing, resistance to sweat, rub resistance, it is deep to be liked by consumer.
The drift that hair can be achieved in the combination of basifier and oxidant is shallow, can so as to catch that gorgeous color provides for hair Energy.Especially for the thick and stiff hair quality of Asian natural black, this shallow process of drift is more important.Shallow degree is floated with oxidation The time direct proportionality of the concentration of agent, the concentration of basifier and effect, but the concentration of oxidant, basifier is higher, alkali The alkalescence of agent is stronger, bigger to the damage of hair.
Ammonium hydroxide arranges in pairs or groups in use, can obtain with oxidant as a kind of conventional basifier and preferably floats shallow effect.Ammonium hydroxide In amino molecule amount it is small, strong to hair penetrating power, alkalescence is suitable, can be incited somebody to action after the particularly hydrogen peroxide use of cooperation oxidant from Right black color development is floated to shallower color development, but the irritation taste of ammonium hydroxide makes consumer experience sense substantially be deteriorated.In such case Under, if reducing the dosage of ammonium hydroxide, ammonium hydroxide is partly or entirely substituted with organic amine such as monoethanolamine, triethanolamine etc., it can be apparent Weaken to the shallow ability of the drift of hair;If reducing the dosage of ammonium hydroxide, a small amount of highly basic or highly basic salt such as sodium carbonate, potassium carbonate are added in Either sodium acid carbonate etc. compounds or adds in a small amount of highly basic or highly basic salt with ammonium hydroxide and compounded with organic amine, although with preferable Float shallow ability, but be bigger to the damage of hair, irritation is big, after dye the resistance to shampoo scourability of the color of hair substantially compared with Difference is that color is easily fallen.The i.e. current shallow composition of drift, which can not also be taken into account, preferably floats shallow effect and relatively low irritation.
Therefore, develop it is a kind of have preferably float shallow effect and the shallow composition of relatively low irritating drift with great research meaning Justice and application value.
The content of the invention
It is an object of the invention to overcome float in the prior art shallow composition can not have both preferably float shallow effect with it is relatively low Stimulation the defects of, a kind of shallow composition of the drift containing tea bran is provided.The shallow composition of drift provided by the invention is added with tea bran, While reducing irritation basifier dosage, have and preferably float shallow effect, and irritation is low, it is small to hair damage.
For achieving the above object, the present invention adopts the following technical scheme that:
A kind of shallow composition of the drift containing tea bran, the shallow composition of the drift include first dose at least containing basifier and tea bran and The mass fraction of tea bran is 1 ~ 60% in second dose at least containing oxidant, described first dose, first dose of moderate stimulation alkali The mass fraction of agent is not higher than 2.0%, and the irritation basifier is ammonium hydroxide or highly basic class basifier.
Tea bran is also tea seed cake, tea seed cake, is a blob of slag of the tea seed after oil expression, and active ingredient is saponin element, is wild mountain Remaining slag after the oil expression of tea oil fruit.Probably contain 12 ~ 18% Tea Saponin, Residual oil in tea seed cake<2%, protein 12 ~ 16%, starch With carbohydrate 30 ~ 50%, fiber 10 ~ 12%, moisture<12%, impurity<2%.Ancient times tradition hair washing tea seed cake.Contain tea soap in tea seed cake Element, protein, natural tea oil etc., long-time service, which has, only considers to be worth doing, is antipruritic, deoils, sterilize, repairing the effect of damaged hair, also bright Aobvious blackening and generating hair effect is one of optimal detergent of the Nature.
Inventor has found after repeatedly attempting, can be with basifier when tea bran is added in the conventional shallow composition of drift It acts synergistically with oxidant, according to, into being grouped into, inventor speculates the cardinal principle for generating this synergistic effect in tea bran Mainly Tea Saponin promotes bleaching action of the oxidant to the pigment in hair, therefore, is reducing irritation basifier dosage While, reach added with the same or similar shallow effect of drift of larger amount of irritation basifier, irritation is low, to hair damage It is small;In addition the addition of tea bran can also repair damaged hair, increase the compliance of hair.Irritation alkali of the present invention Agent refers mainly to have compared with the ammonium hydroxide of strong and stimulating smell and highly basic class basifier, the alkalization in addition to ammonium hydroxide and highly basic class basifier Agent can be summarized as weak irritation basifier, and irritation is smaller.
Preferably, the tea bran is powdered.
Preferably, the mass fraction of tea bran is 5 ~ 40% in the shallow composition of drift.
Basifier selected by the present invention is this field routine basifier, and oxidant is the oxidant of this field routine.
Preferably, the basifier is one in ammonium hydroxide, monoethanolamine, diethanol amine, triethanolamine or aminomethyl propanol Kind is several.
Preferably, the basifier is monoethanolamine, and mass fraction of the basifier in first dose is 5%, the tea The mass fraction of bran is 15%.
Preferably, the oxidant is one kind or several in hydrogen peroxide, urea peroxide, alkali metal bromate or peroxy salt Kind.
The above-mentioned shallow composition of drift can also be achieved dyeing function after necessary colouring component is added.
Preferably, oxidation base and coupling agent are further included for described first dose.
The shallow composition of drift provided by the invention, which has, preferably floats shallow effect, can be on hair by the addition of colouring component Catch gorgeous color;In addition the shallow composition of the drift has relatively low irritation, and small to hair damage, hair is submissive after dye, has Gloss, resistance to shampoo washability are excellent.
Oxidation base of the present invention is the oxidation base of row industry routine;Coupling agent is the idol of this field routine Join agent.
Preferably, the oxidation base is p-phenylenediamine, 2,5 diaminotoluenes, 2- chlorine p-phenylenediamine, p-aminophenyl Phenol, 4- amino -3- methylphenols, N, N- are double(Beta-hydroxy ethyl)P-phenylenediamine, p-methylaminophenol, o-aminophenol, 2, 4- diaminophenols, 4,5- dimethyl -1(2- ethoxys)Pyrazoles or one or more of 4-aminodiphenylamine and its salt.
Preferably, the coupling agent for dimethyl phenylene diamine, 2,4- diaminophenoxy ethanols, methylaminophenol, 2- methyl- 5- amino-phenols, 2- amino -4- oxyethylamines methyl phenyl ethers anisole, 2- amino -3- Hydroxy-pyridines, 4- chloro resorcinols, 2- methylresorcinols two Phenol, 5- amino -6- chlorine o-cresol, 2- methyl -5- (2- hydroxyethylaminos) phenol, resorcinol, 1- naphthols, 1,5- dihydroxy One or more of naphthalene, 1- phenyl -3- methylpyrazole -5- ketone or quinhydrones.
Preferably, the shallow composition of the drift further includes assistant agent, the assistant agent is thickener, antioxidant, oxidation delayed-action activator, Bleeding agent, chelating agent, fragrance, caching agent, dispersant, conditioning agent, silicone oil, film forming agent, ceramide, preservative, conditioner or One or more of opacifier.
Preferably, the shallow composition of drift further includes direct dyes.
Direct dyes of the present invention can be the known acid dyes of field of hairdye, basic-dyeable fibre, disperse dyes, anti- Answering property dyestuff etc..
As acid dyes, such as blueness 1, purple 401, black 401, No. 205 orange, red can be included No. 227, No. 106 red, yellow 203, acid orange 3 etc..
As basic-dyeable fibre, such as it can include that alkali blue 99, bismarck brown 16, bismarck brown 17, alkalescence is red 76, basic yellow 57 etc..
As the direct dyes beyond acid dyes and basic-dyeable fibre, such as 2- nitros-to benzene two can be included The chloro- 4- nitrophenols of amine, 2- amino -6-, 3- nitros-to hydroxyethylaminophenol, 4-nitro-o-phenylenediamine, 4- amino -3- Nitrophenol, 4- hydroxypropyl -3- nitrophenols, double (2- the ethoxys) -2- nitro p-phenylenediamines of N, N-, disperse violet 1, point Dissipate that indigo plant 1, scattered black 9, HC indigo plants 2, HC oranges 1, HC are red 1, HC is red 3, HC Huangs 2, HC Huangs 4, HC Huangs 5 etc..
Above-mentioned direct dyes can be used alone or in combination of two or more, and content is the shallow composition gross mass of drift 0.001~5%, it is preferably 0.01~4%.
Preferably, the pH of the shallow composition of drift is 3 ~ 12;It is further preferable that the pH of the oxidation hair-dye composition for 7 ~ 12;Most preferably, the pH of the oxidation hair-dye composition is 7.5 ~ 11.
The present invention may be employed the acid commonly used in dyeing keratin fibres, alkali or using standard buffer system come PH value is adjusted, to reach the pH value of needs.
The shallow composition of drift provided by the invention is dyed suitable for keratin fiber, especially human hair.
The shallow composition of drift provided by the invention can exist in a variety of manners, such as liquid, lotion or gel shape etc..
Application of the above-mentioned shallow composition of drift in the shallow or hair dyeing product of drift is prepared is also within the scope of the present invention.
Compared with prior art, the present invention has the advantages that:
The shallow composition of drift provided by the invention while irritation basifier dosage is reduced, reaches and is added with added with tea bran The same or similar shallow effect of drift of larger amount of irritation basifier, irritation is low, small to hair damage, while can be to impaired hair Matter carries out maintenance, increases the compliance of hair;The shallow composition of drift added with colouring component, can catch gorgeous face on hair Color, hair is submissive after dye, and good hand touch is glossy, and resistance to shampoo washability is excellent, has larger application value.
Specific embodiment
With reference to embodiment, the present invention will be further described.These embodiments are only that the typical case of the present invention is retouched It states, however, the present invention is not limited thereto.Test method used unless otherwise specified, is conventional method, is made in following embodiments Raw material, reagent etc. are the raw materials and reagents that can be obtained from commercial sources such as conventional markets unless otherwise specified.
Embodiment 1 ~ 8 and 1 ~ 6 emulsus of reference examples drift understain composition
The formula and corresponding test result such as the following table 1 for the shallow composition of drift that embodiment 1 ~ 8 and reference examples 1 ~ 6 provide.Wherein, base-material Formula for cetostearyl alcohol 10g, hexadecyltrimethylammonium chloride 2.5g, isopropyl palmitate 2g, stearic acid list glyceride 2g, propylene glycol 5g, oleyl alcohol 3g, -20 2g of ceteareth, hydroxyethyl cellulose 0.3g, antioxidant 0.2g, chelating agent 0.3g, P- amino-phenol 0.6g, 5- amino 6- chlorine o-cresols 0.7g.
The preparation method for floating shallow composition is that oil-soluble ingredients are mixed and heated to 75 DEG C, by antioxidant, chelating agent hydroxyl Ethyl cellulose, propylene glycol are added in deionized water, and P- amino-phenols, 5- amino 6- chlorine are added in after being heated to 75 DEG C of stirring and dissolvings O-cresol, dissolving is complete, by two oil, water raw material mixing and emulsifyings, after being cooled to room temperature, adds in basifier, tea bran is mixed Solution.
Only containing basifier, oxidant and tea bran in the shallow composition of drift that embodiment 9 and 10 provides, by basifier and tea bran It is mixed to get mixed solution.The mixed solution and hydrogen peroxide combination are that the emulsus in the present embodiment or reference examples floats shallow combination Object.
(1)Hair dyeing step
The hydrogenperoxide steam generator that the pH for appealing embodiment or 6% content of reference examples mixed solution and equivalent is 3 is mixed during use It closes, under the conditions of 25 DEG C of room temperature, is applied on Chinese's nature black hair, after stopping 30 minutes, with 40 DEG C of warm water washings, from So dry.
(2)Testing procedure
Odor Evaluations:Naked nose hears taste evaluation, and 5 people's group assessments marking, 0-5 points, score value is higher, and representative sample smell is milder, Score value is smaller, and to represent penetrating odor stronger.
Float shallow ability:Under available light, range estimation hair drift is shallow and colouring effect, 5 people's group assessments marking, 0-5 divide, Score value is higher, represent hair drift either shallow it is bigger, color is about gorgeous.
Hair feel after dye:Sensory evaluation, 5 people's group assessments marking, 0-5 points, score value is higher, represents hair feel and gets over It is good.
Dye resistance to shampoo washing firmness:Simulation hair washing program, colored hair 40 degree of warm water moistening hairs, and with commercially available Shampoo is blistered 1 minute, then with 40 degree warm water washings 1 minute, is dried and is cycled for one.Xun Huan washing 7 times, afterwards with not washing Model compares aberration.And score, 5 people's group assessments marking, 0-5 point, score value is higher to represent that color aberration is smaller, and color development is more firm Gu.
Wherein, embodiment 9 ~ 10 only carries out floating shallow aptitude tests and Odor Evaluations.
The formula and test result of shallow colouring compositions are floated in 1 embodiment 1 ~ 8 of table
The formula and test result of shallow composition are floated in 2 reference examples 1 ~ 6 of table
Reference examples 1,2 and 3 are the shallow compositions of drift of the prior art.It is gorgeous using hair after the shallow composition hair dyeing of drift in reference examples 1 Beautiful, feel, the washable firmness each side performance of dyeing are good after the shallow ability of hair drift, dye, but smell is pungent, it is difficult to endure. The shallow composition smell of drift in reference examples 2 and 3 is mild, and no sharp aroma is felt good, but uses the drift in comparative example 2 and 3 After shallow composition hair dyeing, feel, the washable firmness each side performance of dyeing are all bad after hair color, the shallow ability of hair drift, dye. Compared to reference examples 1 ~ 6, the shallow composition of drift hair feel, dyeing after shallow ability, dye is floated of the offer of the embodiment of the present invention 1 ~ 10 It will be got well in terms of resistance to shampoo washing firmness, smell is also mild, is not pungent.And with tea bran mass fraction in the shallow composition of drift Increase, every test index advantage is more and more apparent;The shallow composition of drift that embodiment 9 and 10 provides, which has, preferably floats shallow energy Power, smell are not pungent mildly.
11 ~ 18 powdery of embodiment floats shallow composition
The formula and corresponding test result such as the following table 3, preparation process for the shallow composition of drift that embodiment 11 ~ 18 provides are as follows:First will Basifier phase materials, which are added in pulverizer, to be crushed uniformly, adds in base-material phase substance afterwards, crushing is uniform, is eventually adding advance crushing Good tea bran powder, stirs evenly.
Step of having hair dyed and testing procedure are consistent in embodiment 1.
The formula and test result of shallow composition are floated in 3 embodiment 11 ~ 18 of table
As seen from the above table, the powdery that the present embodiment 11 ~ 18 provides floats shallow composition hair feel, dyeing after shallow ability, dye is floated Excellent performance is all shown in terms of resistance to shampoo washing firmness, and smell is mild, is not pungent.
19 ~ 30 gel shape of embodiment floats shallow composition
The gel shape that embodiment 19 ~ 30 provides floats the formula and corresponding test result such as the following table 4 of shallow composition.Preparation process is such as Under:Heating first dose in deionized water to 70 DEG C, by first dose of base-material except all substances of tea bran powder are dissolved in deionization In water, stirring is allowed to be completely dissolved, and adds in tea bran powder afterwards and stirs evenly, is eventually adding alkaline agent and stirs evenly.
Step of having hair dyed and testing procedure are consistent in embodiment 1.
The formula and test result of shallow colouring compositions are floated in 4 embodiment 19 ~ 33 of table
As seen from the above table, the shallow composition of drift provided in this embodiment hair feel, resistance to shampoo washing of dyeing after shallow ability, dye is floated Excellent performance is all shown in terms of firmness, and smell is mild, is not pungent.
Embodiment 34 ~ 40 is free of the shallow composition of drift of permanent type dyestuff intermediate
The formula for the shallow composition of drift without permanent type dyestuff intermediate that embodiment 34 ~ 40 provides and corresponding test result are as follows Shown in table 5.Preparation method is as follows:Alkaline agent in first dose is all added in deionized water and is stirred evenly, adds in tea bran powder afterwards, It stirs evenly.
The formula and test result of shallow composition are floated in 5 embodiment 34 ~ 40 of table
It is floated in embodiment 34 ~ 40 and permanent type dyestuff intermediate is not contained in shallow composition, first dose by with corresponding second Agent 1:1 after mixing, is applied on Asian's black hair, after stopping 30 ~ 45 minutes, with warm water washing, can obtain beautiful Beautiful golden brown.

Claims (10)

1. a kind of shallow composition of the drift containing tea bran, which is characterized in that the shallow composition of the drift include at least containing basifier and First dose and second dose at least containing oxidant of tea bran, the mass fraction of tea bran is 1 ~ 60% in described first dose, described the The mass fraction of one moderate stimulation basifier is not higher than 2.0%, and the irritation basifier is ammonium hydroxide or highly basic class basifier.
2. float shallow composition according to claim 1, which is characterized in that in described first dose the mass fraction of tea bran for 5 ~ 40%。
3. shallow composition is floated according to claim 1, which is characterized in that the basifier is monoethanolamine, diethanol amine, three One or more of ethanolamine or aminomethyl propanol.
4. float shallow composition according to claim 1, which is characterized in that the basifier be monoethanolamine, the basifier Mass fraction in first dose is 5%, and the mass fraction of the tea bran is 15%.
5. shallow composition is floated according to claim 1, which is characterized in that the oxidant is hydrogen peroxide, urea peroxide, alkali One or more of metal bromate or peroxy salt.
6. according to the claim 1 ~ 5 shallow composition of drift, which is characterized in that described first dose further includes oxidation base and idol Join agent.
7. shallow composition is floated according to claim 6, which is characterized in that the oxidation base is p-phenylenediamine, 2,5 diaminos Base toluene, 2- chlorine p-phenylenediamine, para-aminophenol, 4- amino -3- methylphenols, N, N- are double(Beta-hydroxy ethyl)P-phenylenediamine, P-methylaminophenol, o-aminophenol, 2,4- diaminophenols, 4,5- dimethyl -1(2- ethoxys)Pyrazoles or N- phenyl pair One or more of phenylenediamine and its salt.
8. shallow composition is floated according to claim 6, which is characterized in that shallow first dose of the composition of drift further includes assistant agent, The assistant agent for thickener, antioxidant, oxidation delayed-action activator, bleeding agent, chelating agent, fragrance, caching agent, dispersant, conditioning agent, One or more of silicone oil, film forming agent, ceramide, preservative, conditioner or opacifier.
9. shallow composition is floated according to claim 6, which is characterized in that the shallow composition of drift further includes direct dyes.
10. any shallow composition of drift of claim 1 ~ 9 is preparing the application in floating shallow or hair dyeing product.
CN201711449814.3A 2017-12-27 2017-12-27 Tea bran-containing bleaching composition and application thereof Active CN108042428B (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070041924A1 (en) * 2005-08-19 2007-02-22 Bioderm Research Sebum Control Compositions Based on Saponins and Sapogenins
CN106074193A (en) * 2015-10-08 2016-11-09 曾东东 The hair of a kind of dark color floats shallow compositions
CN107320345A (en) * 2017-07-28 2017-11-07 广州市花安堂生物科技有限公司 A kind of double-formulation composition for hair dying and its hair colouring methods

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070041924A1 (en) * 2005-08-19 2007-02-22 Bioderm Research Sebum Control Compositions Based on Saponins and Sapogenins
CN106074193A (en) * 2015-10-08 2016-11-09 曾东东 The hair of a kind of dark color floats shallow compositions
CN107320345A (en) * 2017-07-28 2017-11-07 广州市花安堂生物科技有限公司 A kind of double-formulation composition for hair dying and its hair colouring methods

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
李延卿等: "茶皂素及其在纺织印染中的应用", 《"科隆杯"2013年浙江省纺织印染助剂情报网第23届年会论文集》 *

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