CN108029923A - 一种具有抗过敏效果的益生菌固体饮料生产配方 - Google Patents
一种具有抗过敏效果的益生菌固体饮料生产配方 Download PDFInfo
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Abstract
本发明公开了一种具有抗过敏效果的益生菌固体饮料生产配方,包括如下成分;副干酪乳杆菌、罗伊氏乳杆菌、干酪乳杆菌、鼠李糖乳杆菌、双歧杆菌、酵母β‑葡聚糖;所用原料为对各类过敏反应有较好作用并且拥有多项专利的菌种,在它们各自及相互作用下,可帮助各种过敏患者,有效降低过敏症状,五种活性益生菌与酵母β葡聚糖相辅相成,同时做到促进抗体产生,高效对抗过敏原,提高免疫力,益生菌有效定植于肠道,维持肠道微生态平衡。
Description
技术领域
本发明涉及一种复合益生菌固体饮料,尤其是涉及一种具有抗过敏效果的益生菌固体饮料生产配方。
背景技术
益生菌是指当摄入充足的数量后,能对宿丰产生一种或多种由论证的功能性健康益处的活的微生物。益生菌主要包括乳杆菌属、双歧杆菌属、丙酸菌、芽孢杆菌、埃希氏菌属以及酵母等,其中研究最多,臆用最广的是益生乳酸细菌。益生乳酸细菌能促进机体微生物菌群和酶的平衡以及刺激特异性和非特异性的免疫机制,达到预防某些疾病、促进发育、增强体质、延缓衰老和延长寿命的目的。
现市面上有很多调节肠道、提高免疫力的益生菌产品,包括各类制剂、固体饮料、甚至药品。
本配方是在益生菌具有颇多功能,而几类菌种对某些临床症状具有特殊效果的基础上研究发明的针对过敏体质的复合益生菌固体饮料。
发明内容
本发明要解决的技术问题是克服现有的缺陷,提供一种具有抗过敏效果的益生菌固体饮料生产配方,从而解决上述问题。
为实现上述目的,本发明提供如下技术方案:一种具有抗过敏效果的益生菌固体饮料生产配方,包括如下成分;
副干酪乳杆菌、罗伊氏乳杆菌、干酪乳杆菌、鼠李糖乳杆菌、双歧杆菌、酵母β-葡聚糖。
作为本发明的一种优选技术方案,所述副干酪乳杆菌为60亿个活性单位。
作为本发明的一种优选技术方案,所述罗伊氏乳杆菌为40亿个活性单位。
作为本发明的一种优选技术方案,所述干酪乳杆菌为20亿个活性单位。
作为本发明的一种优选技术方案,所述鼠李糖乳杆菌为20亿个活性单位。
作为本发明的一种优选技术方案,所述双歧杆菌为20亿个活性单位。
与现有技术相比,本发明的有益效果是:该种具有抗过敏效果的益生菌固体饮料生产配方,副干酪乳杆菌是一种分离自健康人的肠道益生菌,可降低过敏患者血液中的IgE含量,并提升其TNF-γ浓度,有效抑制过敏反应,进而降低患者的不适感,临床试验结果显示,所述副干酪乳杆菌可降低血液中IgE含量,过敏病患服用一个月后,流鼻水、打喷嚏、鼻塞的症状显著改善,有效抑制过敏反应,降低患者生活不适感,研究发现,遗传性过敏皮炎以及类似症状的试验动物服用副干酪后,可抑制皮肤发炎和出血,同时过敏指标的血液IgE浓度降至原来的1/3;
罗伊氏乳杆菌是人和动物胃肠道中天然存在的乳杆菌之一,可承受胃酸和胆汁的作用而到达小肠的上部并粘附于小肠壁,对该菌粘附及定植能力的研究表明,罗伊氏乳杆菌细胞外存在粘附素,使其对宿主的黏膜黏液以及肠粘膜上皮细胞均表现较强的粘附能力,粘附素为乳酸菌表面普遍存在的结构成分,其主要成分多为分泌蛋白、糖蛋白、黏多糖类物质等,干酪乳杆菌为益生菌的一种,能够耐受有机体的防御机制,其中包括口腔中的酶、胃液中低PH值和小肠的胆汁酸等,罗伊氏乳杆菌在肠道中的定植具有普遍性,目前还没有研究证明奇定植位点具有特异的选择性,罗伊氏乳杆菌不仅具备乳酸菌主要的有益功效,而且还具备产生广谱抗菌物质的特效,罗伊氏乳杆菌能合成并分泌罗伊氏菌素,是一种为非蛋白质类广谱抗菌物质,可以有效抑制有害菌的生长;
干酪乳杆菌进入人体后可以在肠道内大量存活,起到调节肠内菌群平衡、促进人体消化吸收等作用,所述干酪乳杆菌具有促进细胞分裂,产生抗体免疫,增强人体免疫及预防癌症和抑制肿瘤生长等功能,还具有缓解乳糖不耐症、过敏等作用;
鼠李糖乳杆菌可改善儿童的急性腹泻与抗生素引起之腹泻,增加白血球的防御能力,所述鼠李糖乳杆菌能吸附肠道黏膜醣蛋白和回肠醣蛋白、定殖于肠道内、改善受损肠道黏膜、平衡肠道内菌相、抑制病原菌的生长与抑制E. coli吸附肠道黏膜等多样生理功能,双歧杆菌是1899年由法国学者Tissier从母乳营养儿的粪便中分离出的一种厌氧的革兰氏阳性杆菌,末端常常分叉,故名双歧杆菌,双歧杆菌在人体肠内发酵后可产生乳酸和醋酸,能提高钙、磷、铁的利用率,具有治疗慢性腹泻、治疗便秘、保护肝脏、防治心血管疾病、改善乳糖消化等的作用;
酵母β-葡聚糖的活性结构是由葡萄糖单位组成的多聚糖,酵母β-葡聚糖能够活化巨噬细胞、嗜中性白血球等,从而提高白细胞素、细胞分裂素和特殊抗体的含量,全面刺激机体的免疫系统,大量实验表明,β-葡聚糖可促进体内免疫球蛋白M抗体的产生,以提高体液的免疫能力,同时作为益生元还可以调节肠道菌群结构;
所用原料为对各类过敏反应有较好作用并且拥有多项专利的菌种,在它们各自及相互作用下,可帮助各种过敏患者,包括胃肠道、呼吸道、皮肤及全身的食入性、接触性、吸入性及蛋白质过敏,有效降低过敏症状,五种活性益生菌与酵母β葡聚糖相辅相成,同时做到促进抗体产生,高效对抗过敏原,提高免疫力,益生菌有效定植于肠道,维持肠道微生态平衡。
具体实施方式
对本发明实施例中的技术方案进行清楚、完整地描述,显然,所描述的实施例仅仅是本发明一部分实施例,而不是全部的实施例,基于本发明中的实施例,本领域普通技术人员在没有做出创造性劳动前提下所获得的所有其他实施例,都属于本发明保护的范围。
本发明提供一种技术方案:一种具有抗过敏效果的益生菌固体饮料生产配方,包括如下成分;
副干酪乳杆菌、罗伊氏乳杆菌、干酪乳杆菌、鼠李糖乳杆菌、双歧杆菌、酵母β-葡聚糖。
副干酪乳杆菌为60亿个活性单位。
罗伊氏乳杆菌为40亿个活性单位。
干酪乳杆菌为20亿个活性单位。
鼠李糖乳杆菌为20亿个活性单位。
双歧杆菌为20亿个活性单位。
具体原理:使用时,副干酪乳杆菌降低过敏患者血液中的IgE含量,并提升其TNF-γ浓度,有效抑制过敏反应,进而降低患者的不适感,罗伊氏乳杆菌是人和动物胃肠道中天然存在的乳杆菌之一,可承受胃酸和胆汁的作用而到达小肠的上部并粘附于小肠壁,对该菌粘附及定植能力的研究表明,罗伊氏乳杆菌细胞外存在粘附素,使其对宿主的黏膜黏液以及肠粘膜上皮细胞均表现较强的粘附能力,粘附素为乳酸菌表面普遍存在的结构成分,其主要成分多为分泌蛋白、糖蛋白、黏多糖类物质等,罗伊氏乳杆菌在肠道中的定植具有普遍性,目前还没有研究证明奇定植位点具有特异的选择性,罗伊氏乳杆菌不仅具备乳酸菌主要的有益功效,而且还具备产生广谱抗菌物质的特效;
在急性腹泻期,原有的正常肠道菌群发生快速的改变,对6-36个月环游急性腹泻的儿童进行对比试验,实验检测了处理后水样腹泻的持续时间,罗伊氏乳杆菌组是1.7天,安慰剂组是2.9天;继而统计了处理后第二天腹泻未愈人数的比例,罗伊氏乳杆菌组为26%,安慰剂组为81%,从而证明罗伊氏乳杆菌对治疗儿童腹泻有良好的治疗效果,同时,罗伊氏乳杆菌对缓解由肠道菌群失调所引起的儿童便秘业同样具有良好的效果,儿童通过口服罗伊氏乳杆菌可促进肠道蠕动,从而明显改善儿童慢性便秘的症状,通过实验证明,罗伊氏乳杆菌对婴儿疝气具有显著疗效,通过每天向婴儿早餐添加罗伊氏乳杆菌,可大大改善婴儿疝气的症状,欧洲医学杂志上发表的最新研究表明,让患有功能性肠道回流症的儿童口服罗伊氏乳杆菌,可减轻其肠道膨胀、加速肠道排空,同时可明显降低其肠道食物反流的频率,罗伊氏乳杆菌治疗7天显著缩短肠绞痛患儿哭闹时间;
干酪乳杆菌能够耐受有机体的防御机制,具有促进细胞分裂,产生抗体免疫,增强人体免疫及预防癌症和抑制肿瘤生长等功能,鼠李糖乳杆菌可改善儿童的急性腹泻与抗生素引起之腹泻,增加白血球的防御能力,双歧杆菌在人体肠内发酵后可产生乳酸和醋酸,能提高钙、磷、铁的利用率,酵母β-葡聚糖能够活化巨噬细胞、嗜中性白血球等。
该种具有抗过敏效果的益生菌固体饮料生产配方,副干酪乳杆菌是一种分离自健康人的肠道益生菌,可降低过敏患者血液中的IgE含量,并提升其TNF-γ浓度,有效抑制过敏反应,进而降低患者的不适感,临床试验结果显示,所述副干酪乳杆菌可降低血液中IgE含量,过敏病患服用一个月后,流鼻水、打喷嚏、鼻塞的症状显著改善,有效抑制过敏反应,降低患者生活不适感,研究发现,遗传性过敏皮炎以及类似症状的试验动物服用副干酪后,可抑制皮肤发炎和出血,同时过敏指标的血液IgE浓度降至原来的1/3;
罗伊氏乳杆菌是人和动物胃肠道中天然存在的乳杆菌之一,可承受胃酸和胆汁的作用而到达小肠的上部并粘附于小肠壁,对该菌粘附及定植能力的研究表明,罗伊氏乳杆菌细胞外存在粘附素,使其对宿主的黏膜黏液以及肠粘膜上皮细胞均表现较强的粘附能力,粘附素为乳酸菌表面普遍存在的结构成分,其主要成分多为分泌蛋白、糖蛋白、黏多糖类物质等,干酪乳杆菌为益生菌的一种,能够耐受有机体的防御机制,其中包括口腔中的酶、胃液中低PH值和小肠的胆汁酸等,罗伊氏乳杆菌在肠道中的定植具有普遍性,目前还没有研究证明奇定植位点具有特异的选择性,罗伊氏乳杆菌不仅具备乳酸菌主要的有益功效,而且还具备产生广谱抗菌物质的特效,罗伊氏乳杆菌能合成并分泌罗伊氏菌素,是一种为非蛋白质类广谱抗菌物质,可以有效抑制有害菌的生长;
干酪乳杆菌进入人体后可以在肠道内大量存活,起到调节肠内菌群平衡、促进人体消化吸收等作用,所述干酪乳杆菌具有促进细胞分裂,产生抗体免疫,增强人体免疫及预防癌症和抑制肿瘤生长等功能,还具有缓解乳糖不耐症、过敏等作用;
鼠李糖乳杆菌可改善儿童的急性腹泻与抗生素引起之腹泻,增加白血球的防御能力,所述鼠李糖乳杆菌能吸附肠道黏膜醣蛋白和回肠醣蛋白、定殖于肠道内、改善受损肠道黏膜、平衡肠道内菌相、抑制病原菌的生长与抑制E. coli吸附肠道黏膜等多样生理功能,双歧杆菌是1899年由法国学者Tissier从母乳营养儿的粪便中分离出的一种厌氧的革兰氏阳性杆菌,末端常常分叉,故名双歧杆菌,双歧杆菌在人体肠内发酵后可产生乳酸和醋酸,能提高钙、磷、铁的利用率,具有治疗慢性腹泻、治疗便秘、保护肝脏、防治心血管疾病、改善乳糖消化等的作用;
酵母β-葡聚糖的活性结构是由葡萄糖单位组成的多聚糖,酵母β-葡聚糖能够活化巨噬细胞、嗜中性白血球等,从而提高白细胞素、细胞分裂素和特殊抗体的含量,全面刺激机体的免疫系统,大量实验表明,β-葡聚糖可促进体内免疫球蛋白M抗体的产生,以提高体液的免疫能力,同时作为益生元还可以调节肠道菌群结构;
所用原料为对各类过敏反应有较好作用并且拥有多项专利的菌种,在它们各自及相互作用下,可帮助各种过敏患者,包括胃肠道、呼吸道、皮肤及全身的食入性、接触性、吸入性及蛋白质过敏,有效降低过敏症状,五种活性益生菌与酵母β葡聚糖相辅相成,同时做到促进抗体产生,高效对抗过敏原,提高免疫力,益生菌有效定植于肠道,维持肠道微生态平衡。
最后应说明的是:以上所述仅为本发明的优选实施例而已,并不用于限制本发明,尽管参照前述实施例对本发明进行了详细的说明,对于本领域的技术人员来说,其依然可以对前述各实施例所记载的技术方案进行修改,或者对其中部分技术特征进行等同替换,凡在本发明的精神和原则之内,所作的任何修改、等同替换、改进等,均应包含在本发明的保护范围之内。
Claims (6)
1.一种具有抗过敏效果的益生菌固体饮料生产配方,其特征在于,包括如下成分;
副干酪乳杆菌、罗伊氏乳杆菌、干酪乳杆菌、鼠李糖乳杆菌、双歧杆菌、酵母β-葡聚糖。
2.根据权利要求1所述的一种具有抗过敏效果的益生菌固体饮料生产配方,其特征在于,所述副干酪乳杆菌为60亿个活性单位。
3.根据权利要求1所述的一种具有抗过敏效果的益生菌固体饮料生产配方,其特征在于,所述罗伊氏乳杆菌为40亿个活性单位。
4.根据权利要求1所述的一种具有抗过敏效果的益生菌固体饮料生产配方,其特征在于,所述干酪乳杆菌为20亿个活性单位。
5.根据权利要求1所述的一种具有抗过敏效果的益生菌固体饮料生产配方,其特征在于,所述鼠李糖乳杆菌为20亿个活性单位。
6.根据权利要求1所述的一种具有抗过敏效果的益生菌固体饮料生产配方,其特征在于,所述双歧杆菌为20亿个活性单位。
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