CN108026584B - 非小细胞肺癌诊断用蛋白质生物标志物组及利用其的非小细胞肺癌诊断方法 - Google Patents

非小细胞肺癌诊断用蛋白质生物标志物组及利用其的非小细胞肺癌诊断方法 Download PDF

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CN108026584B
CN108026584B CN201580083066.4A CN201580083066A CN108026584B CN 108026584 B CN108026584 B CN 108026584B CN 201580083066 A CN201580083066 A CN 201580083066A CN 108026584 B CN108026584 B CN 108026584B
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biomarker
lung cancer
small cell
protein
cell lung
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CN108026584A (zh
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金润东
石民京
郑钟河
E·卡蒂柳斯
D·A·齐基
R·M·奥斯特罗夫
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Aptamer Sciences Inc
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    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
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    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
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    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G01N33/57488Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds identifable in body fluids
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    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90Enzymes; Proenzymes
    • G01N2333/988Lyases (4.), e.g. aldolases, heparinase, enolases, fumarase

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CN201580083066.4A 2015-09-11 2015-09-11 非小细胞肺癌诊断用蛋白质生物标志物组及利用其的非小细胞肺癌诊断方法 Active CN108026584B (zh)

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Application Number Priority Date Filing Date Title
PCT/KR2015/009552 WO2017043679A1 (en) 2015-09-11 2015-09-11 Protein biomarker panel for detecting non-small cell lung cancer and method for diagnosing a non-small cell lung cancer by the use thereof

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CN108026584B true CN108026584B (zh) 2021-12-10

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JP (1) JP6857185B2 (ja)
KR (2) KR102078310B1 (ja)
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WO (1) WO2017043679A1 (ja)

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EP3884259A1 (en) * 2018-11-20 2021-09-29 Ventana Medical Systems, Inc. Methods and systems for preparing and analyzing cellular samples for morphological characteristics and biomarker expression
TWI758670B (zh) * 2018-12-24 2022-03-21 奎克生技光電股份有限公司 健康風險評估方法
CN110333341A (zh) * 2019-07-04 2019-10-15 浙江理工大学 一种基于蛋白质芯片技术鉴别丝织品文物样的方法

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2010030697A1 (en) * 2008-09-09 2010-03-18 Somalogic, Inc. Lung cancer biomarkers and uses thereof
WO2011015602A2 (en) * 2009-08-04 2011-02-10 Biosystems International Sas Lung cancer biomarkers
CN102084000A (zh) * 2008-02-01 2011-06-01 总医院有限公司 微泡在医学疾病和病况的诊断、预后以及治疗中的用途
WO2013033019A1 (en) * 2011-08-31 2013-03-07 University Of Utah Research Foundation Methods for determining the integrity of a biological sample
WO2013062515A2 (en) * 2011-10-24 2013-05-02 Somalogic, Inc. Lung cancer biomarkers and uses thereof
WO2013152989A2 (en) * 2012-04-10 2013-10-17 Eth Zurich Biomarker assay and uses thereof for diagnosis, therapy selection, and prognosis of cancer
CN103797131A (zh) * 2011-06-16 2014-05-14 卡里斯生命科学卢森堡控股有限责任公司 生物标志物组合物和方法
CN103874770A (zh) * 2011-08-08 2014-06-18 卡里斯生命科学卢森堡控股有限责任公司 生物标志物组合物和方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3910536B2 (ja) * 2000-12-28 2007-04-25 塩野義製薬株式会社 新規ポリペプチドおよびそのdna
WO2009036123A1 (en) * 2007-09-11 2009-03-19 Cancer Prevention And Cure, Ltd. Method of identifying biomarkers in human serum indicative of pathologies of human lung tissues
EP2857522A3 (en) * 2009-03-12 2015-10-14 Cancer Prevention And Cure, Ltd. Methods of identification, assessment, prevention and therapy of lung diseases and kits thereof including gender-based disease identification, assessment, prevention and therapy
SG168431A1 (en) * 2009-07-23 2011-02-28 Univ Singapore Cancer biomarker and the use thereof
KR20130056855A (ko) * 2010-03-01 2013-05-30 카리스 라이프 사이언스 룩셈부르크 홀딩스 치료진단용 생물학적 지표들
SG186953A1 (en) * 2010-07-09 2013-02-28 Somalogic Inc Lung cancer biomarkers and uses thereof
CN103702835B (zh) 2011-10-24 2016-04-06 惠普发展公司,有限责任合伙企业 流体喷出装置及其方法

Patent Citations (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102084000A (zh) * 2008-02-01 2011-06-01 总医院有限公司 微泡在医学疾病和病况的诊断、预后以及治疗中的用途
WO2010030697A1 (en) * 2008-09-09 2010-03-18 Somalogic, Inc. Lung cancer biomarkers and uses thereof
WO2011015602A2 (en) * 2009-08-04 2011-02-10 Biosystems International Sas Lung cancer biomarkers
CN103797131A (zh) * 2011-06-16 2014-05-14 卡里斯生命科学卢森堡控股有限责任公司 生物标志物组合物和方法
CN103874770A (zh) * 2011-08-08 2014-06-18 卡里斯生命科学卢森堡控股有限责任公司 生物标志物组合物和方法
WO2013033019A1 (en) * 2011-08-31 2013-03-07 University Of Utah Research Foundation Methods for determining the integrity of a biological sample
WO2013062515A2 (en) * 2011-10-24 2013-05-02 Somalogic, Inc. Lung cancer biomarkers and uses thereof
CN103890586A (zh) * 2011-10-24 2014-06-25 私募蛋白质体公司 肺癌生物标记及其用途
WO2013152989A2 (en) * 2012-04-10 2013-10-17 Eth Zurich Biomarker assay and uses thereof for diagnosis, therapy selection, and prognosis of cancer

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
A Novel Serum 4-microRNA Signature for Lung Cancer Detection;Ernest Nadal et al;《Scientific Reports》;20150723;第05卷(第12464期);第1-9页 *

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Publication number Publication date
CN108026584A (zh) 2018-05-11
JP6857185B2 (ja) 2021-04-14
KR20200020958A (ko) 2020-02-26
KR102078310B1 (ko) 2020-02-19
KR20180036787A (ko) 2018-04-09
JP2018528441A (ja) 2018-09-27
KR102087373B1 (ko) 2020-03-10
WO2017043679A1 (en) 2017-03-16

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