CN108020677A - Analysis of protein equipment - Google Patents

Analysis of protein equipment Download PDF

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Publication number
CN108020677A
CN108020677A CN201711284864.0A CN201711284864A CN108020677A CN 108020677 A CN108020677 A CN 108020677A CN 201711284864 A CN201711284864 A CN 201711284864A CN 108020677 A CN108020677 A CN 108020677A
Authority
CN
China
Prior art keywords
kit
loading
fixed frame
motor
analysis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201711284864.0A
Other languages
Chinese (zh)
Inventor
宋昌亮
丁立峰
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beijing Bodian Optical Tech Co ltd
Original Assignee
Beijing Bodian Optical Tech Co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beijing Bodian Optical Tech Co ltd filed Critical Beijing Bodian Optical Tech Co ltd
Priority to CN201711284864.0A priority Critical patent/CN108020677A/en
Publication of CN108020677A publication Critical patent/CN108020677A/en
Pending legal-status Critical Current

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Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1009Characterised by arrangements for controlling the aspiration or dispense of liquids
    • G01N35/1011Control of the position or alignment of the transfer device
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04Details of the conveyor system
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04Details of the conveyor system
    • G01N2035/0439Rotary sample carriers, i.e. carousels
    • G01N2035/0444Rotary sample carriers, i.e. carousels for cuvettes or reaction vessels

Abstract

The invention discloses a kind of analysis of protein equipment, is related to clinical detection technique field, including kit loading attachment, kit pressing device, main shaft device plus curing agent device and kit discharge mechanism.Kit loading attachment includes loading fixed frame, stowage receptacle, loading motor and transmission mechanism;Kit pressing device includes pushing fixed frame, pushes motor, gear, moving member, compression bar, push rod and rotating wheel;Main shaft device includes actuating unit, reaction tray, optoelectronic switch and light blocking part;Add curing agent device to include installing plate plus agent compression bar plus agent compression bar seat plus agent motor and add agent crank;Kit discharge mechanism, including stent, guide rail, pushing block, unloading connecting rod, unloading crank and unloading motor.The analysis of protein equipment of the present invention, kit can be placed continuously, it can be achieved that multiple reaction positions are reused, and test flux greatly improves, and solves the problems, such as that analysis of protein equipment detection range is small, has the value promoted and applied.

Description

Analysis of protein equipment
Technical field
The present invention relates to clinical detection technique field, more particularly to a kind of analysis of protein equipment.
Background technology
POCT (point of care testing) instant detection technique, is that the development to come into vogue recent years is very fast Emerging field, it is easy to carry due to its small volume, it is easily operated the characteristics of, be widely used in each clinical department and experiment Room.
Existing liquid reagent detecting instrument test flux is smaller, can only once place 1-4 kit.And list can only be detected Wavelength or dual wavelength, test event scope are smaller.
At present, there is an urgent need for a kind of wide analysis of protein equipment of detection range.
The content of the invention
It is an object of the invention to provide a kind of analysis of protein equipment, is set with solving analysis of protein existing in the prior art The small technical problem of standby detection range.
To achieve these goals, the present invention uses following technical scheme:
A kind of analysis of protein equipment provided by the invention, including:
Kit loading attachment, including fixed frame, stowage receptacle, loading motor and transmission mechanism are loaded, the stowage receptacle is slided Dynamic to be connected on the loading fixed frame, the transmission mechanism is arranged on the loading fixed frame with the loading motor, One end of the transmission mechanism is connected with the loading motor, and the other end is connected with the stowage receptacle, and the loading motor is used for The stowage receptacle straight reciprocating motion is driven by the transmission mechanism, the stowage receptacle is used to install kit;
Kit pressing device, including push fixed frame, push motor, gear, moving member, compression bar, push rod and rotating wheel, The pushing motor is fixed on the pushing fixed frame, and the gear is arranged on the power output shaft of the pushing motor;Institute State moving member to be slidably connected with the pushing fixed frame, the tooth being meshed with the gear is vertically arranged with the moving member Groove, is vertically arranged with curvilinear pushing groove on the moving member;The compression bar is fixed on the top of the moving member, described Push rod is horizontally disposed with, and the push rod is slidably connected with the pushing fixed frame;The rotating wheel is rotatably connected on the push rod One end, and the rotating wheel be arranged on it is described pushing groove in;
Main shaft device, including actuating unit, reaction tray, optoelectronic switch and light blocking part, in the reaction tray along its circumferential direction according to Minor tick is provided with multiple kit mounting grooves;The actuating unit is connected with the reaction tray, for driving the reaction tray Rotation;The light blocking part is fixedly connected with the reaction tray;The optoelectronic switch is located at the lower section of the light barrier, for detecting The position of the light barrier;
Add curing agent device, including installing plate plus agent compression bar plus agent compression bar seat plus agent motor and add agent crank, it is described plus Agent compression bar is arranged on the top of the installing plate by described plus agent compression bar seat;Described plus agent motor is arranged on the installing plate Top, by adding agent compression bar straight reciprocating motion described in described plus agent crank handle turns;
Kit discharge mechanism, including stent, guide rail, pushing block, unloading connecting rod, unloading crank and unloading motor, it is described to unload The side that motor is arranged on the stent is carried, the guide rail is arranged on the opposite side of the stent;One end of the unloading crank It is connected with the unloading motor, the other end passes through the stent;The unloading crank described in the unloading connecting rod drive by pushing away Block straight reciprocating motion on the bracket.
Further, the transmission mechanism includes connecting rod, loads crank, impeller and track;
One end of the connecting rod and one end of the loading crank are rotatablely connected, the other end of the connecting rod and the promotion Part is rotatablely connected, and the other end for loading crank is connected with the loading motor;
The track is linear, and the impeller is slidably connected with the track.
Further, the bottom for loading fixed frame is provided with mounting groove, and the transmission mechanism is arranged on the loading The top of fixed frame.
Further, the kit loading attachment further includes electromagnet, iron core and gate;
The electromagnet is fixedly connected on the loading fixed frame;
The iron core is fixed on the gate, and the gate is rotatably connected on the loading fixed frame, and described Electromagnet is set with the gate spacer.
Further, the gate is vertically arranged in the one end of the stowage receptacle away from the transmission device;
The opening that the impeller is set for card is provided with the gate.
Further, the moving member includes movable block and the compression bar seat being fixed at the top of the movable block;
The teeth groove is arranged on the movable block, and the compression bar is fixed on the compression bar seat.
Further, fixed block is provided with the pushing fixed frame, horizontal concrete chute is provided with the fixed block, it is described Push rod is slidably arranged in the horizontal concrete chute;
Upright guide rail is provided with the pushing fixed frame, upright slide block is provided with the moving member, it is described vertical sliding Block is arranged in the upright guide rail.
Further, first pilot trench and the second pilot trench for pushing groove and including from top to bottom setting;
The teeth groove is arranged on one end of the moving member;
First pilot trench and second pilot trench are vertically arranged, and the distance of the first pilot trench to the teeth groove is less than Second pilot trench to the teeth groove distance.
Further, the actuating unit includes fixed seat, driving wheel and the master being fixedly and coaxially connected with the driving wheel Axis;
The upper end of the main shaft is fixedly connected with the center of the reaction tray;
The main shaft is rotatablely connected with the fixed seat, and the fixed seat is stretched out in the lower end of the main shaft.
Further, the actuating unit further includes bearing;
The bearing is fixed in the fixed seat;
The main shaft is fixedly connected with the inner wall of the bearing;
Also, the bearing is two, and two bearings are from top to bottom disposed in the fixed seat.
Analysis of protein equipment provided by the invention, in use, kit to be installed on to the stowage receptacle of kit loading attachment On, loading motor drives stowage receptacle to move along a straight line on fixed frame by transmission mechanism, and stowage receptacle is pushed to reaction tray On kit mounting groove in, loading motor by transmission mechanism drive stowage receptacle be back moved to initial position;And then reagent The pushing motor-driven gear of box pressing device rotates, and driving moving member moves down, and the pushing groove on moving member is also to moving down Dynamic, curvilinear due to pushing groove, the movement for pushing groove make it that pushing groove applies rotating wheel horizontal applied force, and rotating wheel is horizontal Mobile, rotating wheel driving push rod is horizontal on fixed frame to be slided, and the mouth structure of breaking of kit is broken into two with one's hands, meanwhile, in moving member During moving down, compression bar moves down, and the rubber plug of kit is pushed down on, and by the reagent bottle in kit Reagent is pushed in reaction cup;Then, the actuating unit driving reaction disc spins of main shaft device, reaction tray drive kit rotation To the corresponding position for adding curing agent device, add the pushing motor of curing agent device by adding agent crank handle turns to add agent compression bar downward It is mobile, curing agent is added into kit, multiple kits can be rotated to adding at curing agent device, so as to be consolidated successively successively Agent is added;During reaction tray is rotating, light barrier is rotated with reaction tray, and optoelectronic switch detects the position of light barrier, and By the rotation angle of the position judgment light barrier of light barrier, so as to judge the rotation angle of reaction tray.
For analysis of protein equipment provided by the invention in test, kit can continuously place, it can be achieved that multiple reaction positions Reuse, really realize the follow-on test pattern identical with full-automatic instrument, test flux greatly improves, and solves albumen point The problem of desorption device detection range is small, is adapted for promoting and applying.
Brief description of the drawings
, below will be to specific in order to illustrate more clearly of the specific embodiment of the invention or technical solution of the prior art Embodiment or attached drawing needed to be used in the description of the prior art are briefly described, it should be apparent that, in describing below Attached drawing is some embodiments of the present invention, for those of ordinary skill in the art, before not making the creative labor Put, other attached drawings can also be obtained according to these attached drawings.
Fig. 1 is a kind of structure diagram of analysis of protein equipment provided in an embodiment of the present invention;
Fig. 2 is a kind of structure diagram of analysis of protein equipment provided in an embodiment of the present invention;
Fig. 3, which is that reagent is box-packed in a kind of analysis of protein equipment provided in an embodiment of the present invention, carries the structure diagram put;
Fig. 4, which is that reagent is box-packed in a kind of analysis of protein equipment provided in an embodiment of the present invention, carries another structural representation put Figure;
Fig. 5, which is that reagent is box-packed in a kind of analysis of protein equipment provided in an embodiment of the present invention, carries the partial structurtes signal put Figure;
Fig. 6, which is that reagent is box-packed in a kind of analysis of protein equipment provided in an embodiment of the present invention, carries the application schematic diagram put;
Fig. 7 is the structure diagram of kit pressing device in a kind of analysis of protein equipment provided in an embodiment of the present invention;
Fig. 8 is the partial structurtes signal of kit pressing device in a kind of analysis of protein equipment provided in an embodiment of the present invention Figure;
Fig. 9 is the partial structurtes signal of kit pressing device in a kind of analysis of protein equipment provided in an embodiment of the present invention Figure;
Figure 10 is the structure diagram of main shaft device in a kind of analysis of protein equipment provided in an embodiment of the present invention;
Figure 11 is the schematic cross-sectional view of main shaft device in a kind of analysis of protein equipment provided in an embodiment of the present invention;
Figure 12 is the partial structural diagram of main shaft device in a kind of analysis of protein equipment provided in an embodiment of the present invention;
Figure 13 is another partial structurtes signal of main shaft device in a kind of analysis of protein equipment provided in an embodiment of the present invention Figure;
Figure 14 is the structure diagram of kit discharge mechanism in a kind of analysis of protein equipment provided in an embodiment of the present invention;
Figure 15 is in a kind of analysis of protein equipment provided in an embodiment of the present invention plus the structure diagram of curing agent device;
Figure 16 is the structure diagram of postnotum component in a kind of analysis of protein equipment provided in an embodiment of the present invention;
Figure 17 is the structure diagram of heating unit in a kind of analysis of protein equipment provided in an embodiment of the present invention.
Reference numeral:
0- kits;01- kits load position;02- goes out waste port;03- heat emission holes;
1- kit loading attachments;10- sliding blocks;11- fixed frames;12- loading motors;13- loads crank;14- connecting rods; 15- stowage receptacles;16- impellers;17- gates;18- electromagnet;19- tracks;
2- kit pressing devices;20- upright slide blocks;21- pushes motor;22- pushes fixed frame;23- gears;24- is moved Motion block;25- compression bar seats;26- compression bars;27- fixed blocks;28- push rods;29- rotating wheels;
3- main shaft devices;30- fixing pieces;31- reaction trays;32- transfer panels;33- main shafts;34- driving wheels;35- fixed seats; 36- bearings;37- baffle rings;38- light barriers;39- optoelectronic switches;311- kit mounting grooves;312- gap;
4- kit discharge mechanisms;40- guide rails;41- unloads motor;42- stents;43- unloads crank;44- unloads connecting rod; 45- pushing blocks;
5- adds curing agent device;50- adds agent compression bar;51- adds agent motor;52- mounting bases;53- installing plates;54- adds agent bent Handle;55- adds agent compression bar seat;
6- optical path components;
7- postnotum components;71- back board mounts;72- ground terminals;73- network interfaces;74-RS-232 serial ports;75-USB Mouthful;76- band filter Switching Power Supplies;
8- heating units;81- heating collars;82- heating tapes;83- heat-preservation cottons;84- temperature protection switch;85- temperature sensing Device;86- catch.
Embodiment
Technical scheme is clearly and completely described below in conjunction with attached drawing, it is clear that described implementation Example is part of the embodiment of the present invention, instead of all the embodiments.Based on the embodiments of the present invention, ordinary skill Personnel's all other embodiments obtained without making creative work, belong to the scope of protection of the invention.
In the description of the present invention, it is necessary to explanation, term " " center ", " on ", " under ", "left", "right", " vertical ", The orientation or position relationship of the instruction such as " level ", " interior ", " outer " be based on orientation shown in the drawings or position relationship, merely to Easy to describe the present invention and simplify description, rather than instruction or imply signified device or element must have specific orientation, With specific azimuth configuration and operation, therefore it is not considered as limiting the invention.In addition, term " first ", " second ", " the 3rd " is only used for description purpose, and it is not intended that instruction or hint relative importance.
In the description of the present invention, it is necessary to illustrate, unless otherwise clearly defined and limited, term " installation ", " phase Even ", " connection " should be interpreted broadly, for example, it may be being fixedly connected or being detachably connected, or be integrally connected;Can To be mechanical connection or be electrically connected;It can be directly connected, can also be indirectly connected by intermediary, Ke Yishi Connection inside two elements.For the ordinary skill in the art, with concrete condition above-mentioned term can be understood at this Concrete meaning in invention.
Embodiment:
In the alternative of the present embodiment, as Fig. 1 to Fig. 2, Fig. 3 to Fig. 6, Fig. 7 to Fig. 9, Figure 10 to Figure 13, Figure 14, Shown in Figure 15, a kind of analysis of protein equipment provided in this embodiment, including:
Kit loading attachment 1, including load fixed frame 11, stowage receptacle 15, loading motor 12 and transmission mechanism, stowage receptacle 15 are slidably connected on loading fixed frame 11, and transmission mechanism is arranged at loading motor 12 and loads on fixed frame 11, driver One end of structure is connected with loading motor 12, and the other end is connected with stowage receptacle 15, and loading motor 12 is used to drive by transmission mechanism 15 straight reciprocating motion of stowage receptacle, stowage receptacle 15 are used to install kit 0;
Kit pressing device 2, including push fixed frame 22, push motor 21, gear 23, moving member, compression bar 26, push rod 28 and rotating wheel 29, push motor 21 and be fixed on and push on fixed frame 22, gear 23 is arranged on the power output for pushing motor 21 Axis;Moving member is slidably connected with pushing fixed frame 22, and the teeth groove being meshed with gear 23, moving member are vertically arranged with moving member On be vertically arranged with curvilinear pushing groove;Compression bar 26 is fixed on the top of moving member, and push rod 28 is horizontally disposed, and push rod 28 It is slidably connected with pushing fixed frame 22;Rotating wheel 29 is rotatably connected on one end of push rod 28, and rotating wheel 29 is arranged on pushing groove It is interior;
Main shaft device 3, including actuating unit, reaction tray 31, optoelectronic switch 39 and light blocking part, along its circumferential direction in reaction tray 31 It is sequentially arranged at intervals with multiple kit mounting grooves 311;Actuating unit is connected with reaction tray 31, for driving reaction tray 31 to revolve Turn;Light blocking part is fixedly connected with reaction tray 31;Optoelectronic switch 39 is located at the lower section of light barrier 38, for detecting the position of light barrier 38 Put;
Add curing agent device 5, including installing plate 53 plus agent compression bar 50 plus agent compression bar seat 55 plus agent motor 51 and plus agent song Handle 54, the installing plate 53 are arranged on the top of the outer rim of the reaction tray 31 by mounting base 52, add agent compression bar 50 by adding Agent compression bar seat 55 is arranged on the top of installing plate 53;Agent motor 51 is added to be arranged on the top of installing plate 53, by adding agent crank 54 Drive and add 50 straight reciprocating motion of agent compression bar;
Kit discharge mechanism 4, including stent 42, guide rail 40, pushing block 45, unloading connecting rod 44, unloading crank 43 and unloading Motor 41, unloading motor 41 are arranged on the side of stent 42, and guide rail 40 is arranged on the opposite side of stent 42;Unload the one of crank 43 End is connected with unloading motor 41, and the other end passes through stent 42;Unloading crank 43 drives pushing block 45 in stent by unloading connecting rod 44 Straight reciprocating motion on 42.
In the present embodiment, when using this equipment, kit 0 is loaded into position 01 by kit and is installed on stowage receptacle 15 On, the waste material produced in analytic process is discharged by going out waste port 02, also, supplies equipment cooling equipped with heat emission hole 03.
Loading motor 12 drives stowage receptacle 15 to move along a straight line on fixed frame 11 by transmission mechanism, so that by stowage receptacle 15 push to the relevant position in reaction tray 31, and then loading motor 12 drives stowage receptacle 15 back to move by transmission mechanism, It is back to initial position.Kit loading attachment 1 is realized by the cooperation of loading motor 12, transmission mechanism and stowage receptacle 15 to be passed through certainly It is dynamic that kit 0 is pushed into 31 relevant position of reaction tray, so as to ensure that kit 0 accurately pushes to relevant position, improve The precision of 0 installation site of kit, meanwhile, realize the push of kit 0 automatically by mechanism, manpower be greatly saved, Reduce the time, improve detection efficiency.
Push 21 drive gear 23 of motor rotate, the relation that gear 23 is engaged with teeth groove cause gear 23 driving moving member to Lower movement, during moving member moves down, the pushing groove on moving member moves down, curvilinear due to pushing groove, pushes away The movement of indent make it that push groove applies horizontal applied force to rotating wheel 29 so that rotating wheel 29 moves horizontally, and rotating wheel 29 drives Dynamic push rod 28 is horizontal on fixed frame 22 is pushed to be slided, and the mouth structure of breaking of kit 0 is broken into two with one's hands, at the same time, moved by push rod 28 During moving part moves down, compression bar 26 moves down, and compression bar 26 pushes down on the rubber plug of kit 0 so that reagent bottle Interior reagent is pushed in reaction cup.Kit pressing device 2 passes through moving member, compression bar 26, push rod 28 and rotating wheel 29 Coordinate realize to 0 rubber plug of kit push down on and break mouth structure break action into two with one's hands, save manpower and time, substantially increase Detection efficiency.
Actuating unit is connected with reaction tray 31, kit 0 is installed in the kit mounting groove 311 of reaction tray 31, is moved Force mechanisms driving reaction tray 31 rotates, and reaction tray 31 drives kit 0 to rotate to the corresponding position that curing agent adds mechanism, Gu Determine agent addition mechanism curing agent is added in kit 0, multiple kits 0 can be rotated to curing agent successively adds mechanism Place, so as to carry out curing agent addition successively, during reaction tray 31 is rotating, light barrier 38 is rotated with reaction tray 31, photoelectricity The position of the detection light barrier 38 of switch 39, and the rotation angle for the position judgment light barrier 38 for passing through light barrier 38, so as to judge The rotation angle of reaction tray 31;Using driving mechanism by multiple kits 0 in reaction tray 31 turn to successively predeterminated position into Row curing agent adds, that is, the position of kit 0 is adjusted by mechanism, it is more convenient, detection efficiency is improved, meanwhile, The setting of light barrier 38 and optoelectronic switch 39 can make the rotation angle for precisely detecting reaction tray 31, also can precisely adjust reagent The position of box 0, further facilitates use.
Add agent motor 51 to drive and add 50 straight reciprocating motion of agent compression bar, the curing agent in kit 0 is filled into reaction cup It is interior, curing absorption is carried out to the waste reaction solution in reaction cup, prevents biological pollution.
The straight reciprocating motion on stent 42 of pushing block 45, the kit 0 that the test in reaction tray 31 is completed is unloaded.
This analysis of protein equipment, can continuously place kit 0, realize that multiple reaction positions are reused, really realize and complete The identical follow-on test pattern of robot, test flux greatly improve, and detection range is big.
It should be noted that plus agent crank 54 with plus the axis of agent compression bar 50 be mutually perpendicular to;Add and be provided with agent crank 54 Add agent bearing 36;Unload the direction of motion of the axis direction perpendicular to pushing block 45 of crank 43.
And, it is preferable that this analytical equipment is equipped with 24 reaction positions, it can be achieved that constant speed follow-on test altogether;The detection of totally 8 tunnels is solid Standing wave is long and wavelength is matched in part, can be adjusted flexibly according to user demand or region demand.
In the alternative of the present embodiment, transmission mechanism includes connecting rod 14, loads crank 13, impeller 16 and track 19;One end of connecting rod 14 is rotatablely connected with loading one end of crank 13, and the other end and the impeller 16 of connecting rod 14 are rotatablely connected, and is filled The other end for carrying crank 13 is connected with loading motor 12;Track 19 is linear, and impeller 16 is slidably connected with track 19.
In the present embodiment, transmission mechanism includes connecting rod 14, loads crank 13, impeller 16 and track 19, loads electricity One end that the driving of machine 12 loads crank 13 rotates, and the one end for loading the other end drive link 14 of crank 13 rotates, due to connecting rod 14 other end and the track 19 of linear are slidably connected, and therefore, connecting rod 14 does straight reciprocating motion along track 19;Transmission mechanism Include the form of connecting rod 14, loading crank 13, impeller 16 and track 19, its is simple in structure, facilitates processing and fabricating, subtracts at the same time The weight and volume of light kit loading attachment 1.
It is appreciated that the structure type of transmission mechanism can be a variety of, for example, transmission mechanism includes gear structure and tooth Bar;The power output axis connection of gear structure and loading motor 12, rack are slidably connected on fixed frame 11, gear structure and tooth Bar engages, and stowage receptacle 15 is fixedly connected with rack.Kit 0 is installed in stowage receptacle 15 by user, and loading motor 12 drives Gear structure rotates, and gear structure drive rack linear motion, rack drives stowage receptacle 15 moves along a straight line.
And for example, transmission mechanism includes cam mechanism, the cam of cam mechanism and the power output axis connection of loading motor 12, The driven member of cam mechanism is slidably connected with fixed frame 11, meanwhile, stowage receptacle 15 is fixedly connected with driven member.When in use, make Kit 0 is installed in stowage receptacle 15 by user, and 12 driving cam of loading motor rotates, and is promoted during cam rotation driven Part does linear reciprocation movement, and driven member driving stowage receptacle 15 does linear reciprocation movement.
In the alternative of the present embodiment, the bottom of impeller 16 is provided with sliding block 10, is provided with track 19 with sliding The sliding slot that block 10 coordinates;Two mounting holes are arranged at intervals with impeller 16, one end of connecting rod 14 turns with one of mounting hole Dynamic connection.
In the present embodiment, the bottom of impeller 16 is provided with sliding block 10, which is slidably arranged on track 19 Sliding slot, during impeller 16 moves, sliding block 10 moves in sliding slot, and the fit form of sliding block 10 and sliding slot, which may be guided, to be pushed away The linear motion of moving part 16, so that keeping stablizing during impeller 16 moves;Two peaces are provided with impeller 16 Fill hole, connecting rod 14 and one of mounting hole are rotatablely connected, and connecting rod 14 is connected with different mounting holes, the movement of impeller 16 away from From difference.User can optionally with need to select connecting rod being connected with one of mounting hole, two mounting holes Set the distance that can move stowage receptacle 15 adjustable, add the applicability of device.
In the alternative of the present embodiment, the bottom for loading fixed frame 11 is provided with mounting groove, and transmission mechanism is arranged on Load the top of fixed frame 11.
In the present embodiment, mounting groove is set in the bottom of fixed frame 11, can facilitates and fixed frame 11 is installed on default portion On part, transmission mechanism and impeller 16 are arranged on to the top of fixed frame 11, can make compact-sized, makes full use of space.
In the alternative of the present embodiment, kit loading attachment 1 further includes electromagnet 18, iron core and gate 17; Electromagnet 18, which is fixedly connected on, to be loaded on fixed frame 11;Iron core is fixed on gate 17, and gate 17 is rotatably connected on loading and fixes On frame 11, and electromagnet 18 is arranged at intervals with gate 17.
In the present embodiment, when electromagnet 18 is powered, electromagnet 18 attracts iron core to be moved towards the direction of electromagnet 18, iron Core driving gate 17 rotates, so that the passage that stowage receptacle 15 is moved is opened, at this time, carries out the push of kit 0.When having used Bi Hou, electromagnet 18 is powered off, and electromagnet 18 loses magnetic force, 17 ineffective power of gate, and gate 17 rotates round about, from And the passage for moving stowage receptacle 15 is closed;The cooperation of gate 17 and electromagnet 18 constitutes mistaken collision preventing system, that is, working as has examination When agent box 0 needs to be loaded into reaction tray 31, gate 17 will automatically open up, when machine does not allow to add kit 0, gate 17 It may turn off, avoid shifting kit 0 near reaction tray 31 onto due to touching by mistake, cause the system failure.
In the alternative of the present embodiment, gate 17 is vertically arranged in the one end of stowage receptacle 15 away from transmission device;Lock The opening that impeller 16 is set for card is provided with door 17.
In the present embodiment, gate 17 is vertically arranged in one end of stowage receptacle 15, and the end of stowage receptacle 15 is away from transmission Mechanism, that is, one end of stowage receptacle 15 sets transmission mechanism, the other end sets gate 17, and so setting can be such that gate 17 will fill Carry the one end of seat 15 away from transmission mechanism to open or close, its is compact-sized;It is provided with gate 17 and sets impeller for card 16 opening, when gate 17 is closed, the opening on gate 17 is fastened on impeller 16, and the fit structure form is simple, together When can mitigate the weight of gate 17.
In the alternative of the present embodiment, gate 17 is in the form of sheets.
In the present embodiment, gate 17 in the form of sheets, can further reduce the weight of gate 17, so that mitigating kit loads dress Put 1 weight.
In the alternative of the present embodiment, moving member includes movable block 24 and is fixed on the compression bar seat at the top of movable block 24 25;Teeth groove is arranged on movable block 24, and compression bar 26 is fixed on compression bar seat 25.
In the present embodiment, moving member includes movable block 24 and compression bar seat 25, and compression bar 26 is fixed on compression bar seat 25, teeth groove It is arranged on movable block 24, during use, pushes motor 21 and movement is driven by the fit structure of gear 23 and teeth groove Block 24 moves down, and movable block 24 drives the compression bar 26 on compression bar seat 25 and compression bar seat 25 to move down;Moving member is set For movable block 24 and compression bar seat 25, teeth groove and compression bar seat 25 are distinguished into installation settings, movable block 24 can bear stronger active force, The structure of kit pressing device 2 can be made relatively to stablize.
It is appreciated that the structure type for pushing fixed frame 22 can be a variety of, for example, it can be in side to push fixed frame 22 The fixed frame of shape, it can also be semicircular in shape or the structure type of other irregular shapes to push fixed frame 22.
The structure type of moving member can be a variety of, for example, the movable plate that moving member can be vertically arranged, moving member Can be the structure type of movable block 24;Rotating wheel 29 can be roller, or bearing arrangement.
Also, the shape of movable block 24 can be a variety of, such as:Square, circular, semicircle or other irregular shapes Deng.
The shape of compression bar seat 25 can be a variety of, such as:Square, circular, semicircle or other irregular shapes etc..
In the alternative of the present embodiment, push and be provided with fixed block 27 on fixed frame 22, be provided with fixed block 27 Horizontal concrete chute, push rod 28 are slidably arranged in horizontal concrete chute;Push and be provided with upright guide rail structure on fixed frame 22;Moving member, Actual is movable block 24, is above provided with upright slide block 20;Upright slide block 20 is arranged in upright guide rail structure.
In the present embodiment, fixed block 27 is set on fixed frame 22 is pushed, horizontal concrete chute, push rod are set on fixed block 27 28 are slidably arranged in horizontal concrete chute, during the work time, push motor 21 and drive movement by the cooperation of gear 23 and teeth groove Part moves down, and moving member drives rotating wheel 29 to move horizontally by pushing groove thereon, and 29 driving push rod of rotating wheel 28 is horizontal It is mobile, so that push rod 28 breaks the mouth structure of breaking of reagent bottle bottom into two with one's hands;The water of the bootable push rod 28 of setting of horizontal concrete chute Translation is dynamic so that push rod 28 is moved according to default direction, during improving whole 2 use of kit pressing device Stability and precision.
Upright guide rail structure is set on fixed frame 22 is pushed, upright slide block 20 is set on moving member, upright slide block 20 is set Put in upright guide rail structure.During moving member moves down, upright slide block 20 moves in upright guide rail structure;It is perpendicular The cooperation of straight sliding block 20 and upright slide block 20 can play guiding function to the movement of moving member so that moving member is according to default road Footpath is slided, and improves stability and precision when moving member moves.
In the alternative of the present embodiment, rotating wheel 29 is bearing arrangement.
In the present embodiment, bearing arrangement is existing structure, is convenient to process and mount, meanwhile, its lighter in weight of bearing arrangement, Alleviate the weight of whole kit pressing device 2.
In the alternative of the present embodiment, the first pilot trench and the second pilot trench that groove includes from top to bottom setting are pushed;Tooth Groove is arranged on one end of moving member;First pilot trench and the second pilot trench are vertically arranged, and the distance of the first pilot trench to teeth groove is less than the Two pilot trench to teeth groove distance.
In the present embodiment, pushing groove includes the first pilot trench and the second pilot trench, and the first pilot trench is located at the top of the second pilot trench, And the second pilot trench is compared, the first pilot trench is closer to teeth groove, during the work time, pushes motor 21 and drives moving member to move down, First pilot trench and the second pilot trench move down, and rotating wheel 29 is moved in the first pilot trench by the second pilot trench, due to the first pilot trench more Add close to teeth groove, therefore, rotating wheel 29 is moved towards the direction of teeth groove, so that mouth knot is broken in reagent bottle bottom by push rod 28 Structure is broken into two with one's hands;The position of first pilot trench and the second pilot trench is set so that push rod 28 is moved towards the direction of teeth groove, and reagent bottle is placed on Close to one end of teeth groove, such setting may be such that kit pressing device 2 is compact-sized.
In the alternative of the present embodiment, fixed frame 22 is pushed in the form of sheets.
In the present embodiment, it will push against fixed frame 22 and be arranged to laminated structure, the weight for pushing fixed frame 22 can be mitigated, at the same time Reduce the volume for pushing fixed frame 22, so as to reduce the volume of kit pressing device 2, improve space availability ratio, and conveniently Kit pressing device 2 is fitted in other preset components by user.
In the alternative of the present embodiment, pushing fixed frame 22 includes vertical fixed plate and horizontal fixed plate, and level is solid Fixed board is fixedly connected on the bottom of vertical fixed plate.
In the present embodiment, pushing fixed frame 22 includes vertical fixed plate and horizontal fixed plate, and horizontal fixed plate is fixed on perpendicular The bottom of straight fixed plate, vertical fixed plate can conveniently push the installation of the components such as motor 21, moving member, and horizontal fixed plate can facilitate It will push against fixed frame 22 and carry out installation cooperation with other preset components, so that easy to use.
In the alternative of the present embodiment, the both sides that motor 21 is separately positioned on vertical fixed plate with moving member are pushed.
In the present embodiment, motor 21 and the mobile both sides for being located at vertical fixed plate respectively are pushed, can so make vertical fixation The space of plate both sides is fully used, and reduces pressing device the space occupied, at the same time so that vertical fixed plate both sides stress Stablize, improve the stability of pressing device in use.
In the alternative of the present embodiment, actuating unit includes fixed seat 35, driving wheel 34 and coaxial with driving wheel 34 The main shaft 33 being fixedly connected;The upper end of main shaft 33 is fixedly connected with the center of reaction tray 31;Main shaft 33 is rotated with fixed seat 35 to be connected Connect, and fixed seat 35 is stretched out in the lower end of main shaft 33.
Also, light barrier 38 is fixed on main shaft 33, optoelectronic switch 39 is fixed in fixed seat 35.
In the present embodiment, actuating unit includes driving wheel 34 and main shaft 33, and motor drives driving wheel 34 to rotate, driving wheel 34 drive shafts 33 rotate, and main shaft 33 drives reaction tray 31 to rotate, and the structure type of driving wheel 34 and main shaft 33 is simple, and centre passes Dynamic component is few, improves the drive efficiency of motor, while reduces the volume of main shaft device 3, reduces the occupancy of main shaft device 3 Space.
Motor drives driving wheel 34 to rotate, and the drive main shaft 33 of driving wheel 34 is relatively fixed seat 35 and rotates, and main shaft 33 drives instead 31 rotations should be coiled.At the same time, main shaft 33 drives light barrier 38 to rotate, and optoelectronic switch 39 is motionless, and the detection of optoelectronic switch 39 is in the light The position of piece 38;Fixed seat 35 plays fixation in main shaft device 3, and the grade component of optoelectronic switch 39 is integrated in fixed seat 35 On, the fixed installation of miscellaneous part is facilitated, while be moved easily main shaft device 3.
In the alternative of the present embodiment, light barrier 38 is sector;The center of circle of light barrier 38 is fixed with reaction tray 31 to be connected Connect.
In the present embodiment, light barrier 38 is sector, and the center of circle of light barrier 38 is fixedly connected with reaction tray 31, that is, fan-shaped Center location be fixedly connected with reaction tray 31, main shaft 33 drives reaction tray 31 and light barrier 38 at the same time, and optoelectronic switch 39 passes through The rotation angle of reaction tray 31 is detected in the position for detecting light barrier 38, so as to precisely adjust the position of kit 0;By light barrier 38 are arranged to fan-shaped, and light barrier 38 rotates the front and rear shielded area to 39 light beam of optoelectronic switch of optoelectronic switch 39 and changes, And this kind change is carried out in regular, accurately adjusted so as to carry out rule to reaction tray 31.
In the alternative of the present embodiment, actuating unit further includes bearing 36;Bearing 36 is fixed at fixed seat 35 It is interior;Main shaft 33 is fixedly connected with the inner wall of bearing 36;Also, bearing 36 is two, and two bearings 36 are from top to bottom arranged at intervals In fixed seat 35.
In the present embodiment, main shaft 33 is rotatablely connected by bearing 36 and fixed seat 35, and bearing 36 can be by main shaft 33 with fixing Seat 35 between friction consumption be converted to bearing 36 inside friction consumption, avoid between shaft and fixed seat 35 because it is rubbed more and It is impaired;Bearing 36 is arranged to two, main shaft 33 is rotatablely connected by two bearings 36 with fixed seat 35, and two bearings 36 can make 33 stability under loading of main shaft, while the active force that each bearing 36 is born is also reduced, extend the service life of bearing 36.
It is appreciated that driving wheel 34 is belt pulley, reaction tray 31 is fixedly connected by transfer panel 32 with main shaft 33, reaction tray There is cylinder finger setting between 31 and transfer panel 32;Two 36 inner rings of bearing and main shaft 33 are that transition coordinates, two 36 outer rings of bearing It is clearance fit with fixed seat 35, transfer panel 32 and main shaft 33 are that transition coordinates, and baffle ring 37 is stuck in the relevant position of main shaft 33, this Sample can not only ensure the concentricity of reaction tray 31 and main shaft 33 but also convenient installation;Synchronous pulley is installed on 31 ring flange of reaction tray On, not only ensured the concentricity of 33 rotating mechanism of main shaft, but also ensure the collection of valid data, and it is easy for installation, integrated level is high, knot Structure is reliable, saves the set-up time.
In the alternative of the present embodiment, on the edge of reaction tray 31, along the circumferential direction of reaction tray 31, it is arranged at intervals successively There are multiple gap 312.
In the present embodiment, multiple gap 312 are provided with the edge of reaction tray 31, peace can be set at multiple gap 312 The components such as curing agent addition mechanism are filled, so as to facilitate reaction tray 31 and the position of miscellaneous part to install.
In the alternative of the present embodiment, main shaft device 3 further includes fixing piece 30;The upper end of fixing piece 30 and fixed seat 35 are fixedly connected, and lower end is fixedly connected with optoelectronic switch 39
In the present embodiment, main shaft device 3 further includes fixing piece 30, and optoelectronic switch 39 is solid by fixing piece 30 and fixed seat 35 Fixed connection, user can set the position in fixed seat 35 of optoelectronic switch 39 by the structure difference of fixing piece 30, from And facilitate the setting position of optoelectronic switch 39.
Wherein, the structure type of fixing piece 30 can be a variety of that, for example, fixing piece 30 is fixed disk, optoelectronic switch 39 is set Put on the edge of fixed disk, the rotatable fixed disk of user, so as to adjust the position of optoelectronic switch 39.
In the alternative of the present embodiment, fixing piece 30 is L-shaped fixed strip;The upper end of fixed strip and fixed seat 35 It is fixedly connected, optoelectronic switch 39 is fixedly connected with the lower face of fixed strip.
In the present embodiment, fixing piece 30 is L-shaped fixed strip, and the upper end of L-shaped is fixedly connected with fixed seat 35, L-shaped Optoelectronic switch 39 is fixed with the end face of bottom, the setting of L-shaped can facilitate the installation of optoelectronic switch 39.
In the alternative of the present embodiment, analysis of protein equipment provided in this embodiment further includes:
Optical path component 6, including sequentially connected illuminator component, optical fiber and detection components;
Postnotum component 7, as shown in figure 16, including back board mount 71, ground terminal 72, network interface 73, RS-232 serial ports 74th, USB port 75 and band filter Switching Power Supply 76;
Heating unit 8, as shown in figure 17, including heating collar 81, heating tape 82, heat-preservation cotton 83, temperature protection switch 84, temperature Degree sensor 85 and catch 86, heating tape 82 are arranged between heating collar 81 and heat-preservation cotton 83;Heating collar 81 reacts kit 0 Cup is incubated;Temperature range is 37 DEG C ± 0.1 DEG C after stabilization;
Reagent mixes structure, for driving the needle in reaction cup to mix reaction solution;
Barcode scanning mechanism, for being read out to 0 relevant information of kit.
The complete machine workflow of the analysis of protein equipment of the present embodiment can be summarized as:
Start-heating collar 81 preheats-loaded reagent box 0-addition reagent R1 (being carried out at the same time stirring)-addition reagent R2 (being carried out at the same time stirring)-data acquisition-addition curing agent-kit 0 unloads.
Finally it should be noted that:The above embodiments are only used to illustrate the technical solution of the present invention., rather than its limitations;To the greatest extent Pipe is described in detail the present invention with reference to foregoing embodiments, it will be understood by those of ordinary skill in the art that:Its according to Can so modify to the technical solution described in foregoing embodiments, either to which part or all technical characteristic into Row equivalent substitution;And these modifications or replacement, the essence of appropriate technical solution is departed from various embodiments of the present invention technology The scope of scheme.

Claims (10)

  1. A kind of 1. analysis of protein equipment, it is characterised in that including:
    Kit loading attachment, including fixed frame, stowage receptacle, loading motor and transmission mechanism are loaded, the stowage receptacle, which is slided, to be connected It is connected on the loading fixed frame, the transmission mechanism is arranged on the loading fixed frame with the loading motor, described One end of transmission mechanism is connected with the loading motor, and the other end is connected with the stowage receptacle, and the loading motor is used to pass through The transmission mechanism drives the stowage receptacle straight reciprocating motion, and the stowage receptacle is used to install kit;
    Kit pressing device, including push fixed frame, push motor, gear, moving member, compression bar, push rod and rotating wheel, it is described Push motor to be fixed on the pushing fixed frame, the gear is arranged on the power output shaft of the pushing motor;The shifting Moving part is slidably connected with the pushing fixed frame, and the teeth groove being meshed with the gear, institute are vertically arranged with the moving member State and curvilinear pushing groove is vertically arranged with moving member;The compression bar is fixed on the top of the moving member, the push rod It is horizontally disposed, and the push rod is slidably connected with the pushing fixed frame;The rotating wheel is rotatably connected on the one of the push rod End, and the rotating wheel is arranged in the pushing groove;
    Main shaft device, including actuating unit, reaction tray, optoelectronic switch and light blocking part, in the reaction tray along its it is circumferential successively between Every being provided with multiple kit mounting grooves;The actuating unit is connected with the reaction tray, for driving the reaction disc spins; The light blocking part is fixedly connected with the reaction tray;The optoelectronic switch is located at the lower section of the light barrier, described for detecting The position of light barrier;
    Add curing agent device, including installing plate plus agent compression bar plus agent compression bar seat plus agent motor and add agent crank, described plus agent pressure Bar is arranged on the top of the installing plate by described plus agent compression bar seat;Described plus agent motor is arranged on the top of the installing plate Portion, by adding agent compression bar straight reciprocating motion described in described plus agent crank handle turns;
    Kit discharge mechanism, including stent, guide rail, pushing block, unloading connecting rod, unloading crank and unloading motor, the unloading electricity Machine is arranged on the side of the stent, and the guide rail is arranged on the opposite side of the stent;One end of the unloading crank and institute Unloading motor connection is stated, the other end passes through the stent;The unloading crank drives the pushing block to exist by the unloading connecting rod Straight reciprocating motion on the stent.
  2. 2. analysis of protein equipment according to claim 1, it is characterised in that the transmission mechanism includes connecting rod, loads song Handle, impeller and track;
    One end of the connecting rod and one end of the loading crank are rotatablely connected, and the other end of the connecting rod turns with the impeller Dynamic connection, the other end for loading crank are connected with the loading motor;
    The track is linear, and the impeller is slidably connected with the track.
  3. 3. analysis of protein equipment according to claim 1, it is characterised in that the bottom for loading fixed frame is provided with peace Tankage, the transmission mechanism are arranged on the top of the loading fixed frame.
  4. 4. analysis of protein equipment according to claim 2, it is characterised in that the kit loading attachment further includes electromagnetism Iron, iron core and gate;
    The electromagnet is fixedly connected on the loading fixed frame;
    The iron core is fixed on the gate, and the gate is rotatably connected on the loading fixed frame, and the electromagnetism Iron is set with the gate spacer.
  5. 5. analysis of protein equipment according to claim 4, it is characterised in that the gate is vertically arranged in the stowage receptacle One end away from the transmission device;
    The opening that the impeller is set for card is provided with the gate.
  6. 6. analysis of protein equipment according to claim 1, it is characterised in that the moving member includes movable block and is fixed on Compression bar seat at the top of the movable block;
    The teeth groove is arranged on the movable block, and the compression bar is fixed on the compression bar seat.
  7. 7. analysis of protein equipment according to claim 1, it is characterised in that be provided with fixation on the pushing fixed frame Block, is provided with horizontal concrete chute on the fixed block, the push rod is slidably arranged in the horizontal concrete chute;
    Upright guide rail is provided with the pushing fixed frame, upright slide block is provided with the moving member, the upright slide block is set Put in the upright guide rail.
  8. 8. analysis of protein equipment according to claim 1, it is characterised in that the groove that pushes includes what is from top to bottom set First pilot trench and the second pilot trench;
    The teeth groove is arranged on one end of the moving member;
    First pilot trench and second pilot trench are vertically arranged, and the distance of first pilot trench to the teeth groove is less than described Second pilot trench to the teeth groove distance.
  9. 9. analysis of protein equipment according to claim 1, it is characterised in that the actuating unit includes fixed seat, driving Wheel and the main shaft being fixedly and coaxially connected with the driving wheel;
    The upper end of the main shaft is fixedly connected with the center of the reaction tray;
    The main shaft is rotatablely connected with the fixed seat, and the fixed seat is stretched out in the lower end of the main shaft.
  10. 10. analysis of protein equipment according to claim 9, it is characterised in that the actuating unit further includes bearing;
    The bearing is fixed in the fixed seat;
    The main shaft is fixedly connected with the inner wall of the bearing;
    Also, the bearing is two, and two bearings are from top to bottom disposed in the fixed seat.
CN201711284864.0A 2017-12-07 2017-12-07 Analysis of protein equipment Pending CN108020677A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201711284864.0A CN108020677A (en) 2017-12-07 2017-12-07 Analysis of protein equipment

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Application Number Priority Date Filing Date Title
CN201711284864.0A CN108020677A (en) 2017-12-07 2017-12-07 Analysis of protein equipment

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Publication Number Publication Date
CN108020677A true CN108020677A (en) 2018-05-11

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Country Link
CN (1) CN108020677A (en)

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CN109557328A (en) * 2019-01-02 2019-04-02 江苏普正医疗科技有限公司 A kind of automated loading mechanism of automatic coagulation analyzer
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CN110988337A (en) * 2020-03-03 2020-04-10 潍坊市康华生物技术有限公司 Dark room mechanism for detecting incubation disc

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