CN107998259A - 一种治疗心衰的中药配方及其制备方法 - Google Patents
一种治疗心衰的中药配方及其制备方法 Download PDFInfo
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Abstract
本发明公开了一种用于心衰治疗的中药配方,按重量份数是包括以下中药成分:老茶树根24g,万年青根11g,丹参24g,党参24g,桂枝16g,炒白芍16g,泽泻28g,瓜蒌皮24g,薤白头13g,炙甘草16g。本发明中药组合物的制备和使用方法:先将药材放入砂锅中用冷水浸泡小时,浸泡的水量以淹没药面3cm为宜,将药放在火上,用武火熬开,沸腾后改用文火保持微沸状态,第一次煎煮50分钟,将药液倒出,第二次煎煮加入以刚淹没药渣2‑3cm的热水,煎煮30分钟,将药液倒出,将2次药液混合为1剂,每天1剂,分早晚温服。
Description
技术领域
本发明属于中药组合物,具体地说,是涉及一种用于心衰治疗的中药配方及其制备方法。
背景技术
心力衰竭是指任何原因造成的心肌损伤,使心肌结构和功能发生改变,导致心室泵血功能降低而引起的复杂的临床综合征,是各种心脏病的终末阶段。随着人口老龄化进程的加快和高血压、冠心病等常见心血管病发病率的上升,心力衰竭的患病率正逐渐升高。据国外统计,人群中心衰的患病率约为1.5%~2.0%,而65 岁以上人群可达6%~10%。目前美国的心力衰竭患者约有500万人,每年新诊断病例约40万,每年约有25万人死于心衰,每年用于治疗心衰的直接费用超过70亿美元,其住院费用是所有恶性肿瘤费用的2倍。而在我国,成年人心衰的患病率为0.9%,其中男性为0.7%,女性为1.0%,我国心衰的患病率虽低于西方国家,但由于我国人口基数大,按这个患病率计算,我国目前35~74岁成年人中仍约有400 万心衰患者,且随着高血压、冠心病等常见心血管病发病率的增加,心力衰竭发病率呈不断上升的趋势,这不仅给患者及其家人带来极大痛苦,而且造成了社会沉重的经济负担。因此,心力衰竭的治疗已成为社会和医学界共同关注的重要课题。
在传统祖国医学上,心力衰竭属“胸痹”、“心悸”、“怔忡”、“咳嗽”、“喘证”、“水肿”、“痰饮”和“积聚”等范畴。从古至今,很多中医医家对心力衰竭进行了大量的中医辨证客观化研究,认为中医药治疗充血性心力衰竭有确切疗效,特别是在改善症状,提高生活质量方面有其优越性,而国内用于治疗心力衰竭的中药新药制剂相对较少。
本发明用于心力衰竭治疗的中药配方,针对心力衰竭病因病机,通阳壮气,化瘀利水。针对心力衰竭引发的心悸气喘,张口抬肩,肢冷汗出,下肢水肿,不能平卧,纳呆,抓家略黯,舌质紫黯有瘀斑,苔薄白,脉沉涩而无力等症状的治疗具有显著效果,且疗程短,见效快,安全无毒副作用。
发明内容
本发明的目的在于提供一种用于心力衰竭治疗的中药配方,该中药温通阳气,化瘀利水,对心力衰竭患者减轻病症有较好的疗效。
为了实现上述发明目的,本发明制成该药物有效成分的原料组成及其重量配比为:老茶树根24g,万年青根11g,丹参24g,党参24g,桂枝16g,炒白芍16g,泽泻28g,瓜蒌皮24g,薤白头13g,炙甘草16g。
本发明中药组合物的制备和使用方法:先将药材放入砂锅中用冷水浸泡小时,浸泡的水量以淹没药面3cm为宜,将药放在火上,用武火熬开,沸腾后改用文火保持微沸状态,第一次煎煮50分钟,将药液倒出,第二次煎煮加入以刚淹没药渣2-3cm的热水,煎煮30分钟,将药液倒出,将2次药液混合为1剂,每天1剂,分早晚温服。
发明用于治疗心力衰竭的中药配方,选择天然药物,针对心力衰竭病因病机,各味药材各具其效,互相协调,万年青、老茶树根“二根”相须为用,通阳之功颇强;另伍党参益气,丹参活血,正可赖以补气益心,化瘀散血;再配桂枝以助“二根”通阳之力;配白芍以制“二根”搜刮之过;且桂、芍等量最能营卫调和,贯通脉气;用瓜蒌皮、薤白头则在于理气宽胸化痰,辅桂枝以增强通阳宽胸之功;泽泻利水通淋补阴;炙甘草能甘温益气,缓急养心,并以调和诸药而兼制“二根”之毒。
具体实施方式
实施例1:一种治疗心力衰竭的中药配方,按重量份数包括以下中药成分:老茶树根24g,万年青根11g,丹参24g,党参24g,桂枝16g,炒白芍16g,泽泻28g,瓜蒌皮24g,薤白头13g,炙甘草16g。
实施例2:如果患者水液内停,在上述组分中加茯苓皮16g,生姜皮11g,葶苈子13g。
实施例3:如果患者外邪束表,在上述组分中加麻黄16g,苏梗13g,杏仁16g。
实施例4:如果患者气机失畅,在上述组分中加旋复花13g,降香16g,橘红络16g。
先将药材放入砂锅中用冷水浸泡小时,浸泡的水量以淹没药面3cm为宜,将药放在火上,用武火熬开,沸腾后改用文火保持微沸状态,第一次煎煮50分钟,将药液倒出,第二次煎煮加入以刚淹没药渣2-3cm的热水,煎煮30分钟,将药液倒出,将2次药液混合为1剂,每天1剂,分早晚温服。
以下通过实用例来阐明本发明所述用于治疗心力衰竭的中药配方的临床治疗效果。
1、临床资料
经对280例心力衰竭确诊患者使用本发明中药配方进行治疗,症见:心悸气喘,张口抬肩,肢冷汗出,下肢水肿,不能平卧,纳呆,抓家略黯,舌质紫黯有瘀斑,苔薄白,脉沉涩而无力或结代。
2、疗效标准
显效:症状有显著改善,甚至临床消失;
有效:症状有改善或明显改善;
无效:症状无改善,甚至有加重之趋势。
3、治疗结果
治疗效果:显效263例,占93.93%;有效14例,占5%;无效3例,占1.07%,总有效率98.93%。
典型案例:
孙某,男,72岁,患者素患咳喘及下肢水肿已经五六年,西医诊断:肺源性心脏病、心力衰竭而历年来多次住院,虽有缓解但是仍是生活不能自理,用西药后,效果不佳,因受风寒致病情加剧而就诊,症见形寒心悸,咳嗽气急,端坐呼吸,面色黯灰,全身浮肿,胸闷尿少,唇绀,舌淡黯而偏紫,苔白滑,脉浮细滑数而带结,心电图提示:快速型房颤,不完全性右束支传导阻滞,因是外感风寒动伏饮,心肾阳衰而痰湿阻肺之本虚标实证,治当温阳解表、化饮肃肺为先,服用本发明配方3剂,二诊时,患者步行而至,喜告该药服后甚舒,形寒除而咳喘平,诸恙大瘥,其唇舌则转呈红活之势,脉数细滑而结象显减,唯尚感胸闷、纳呆、少寐而已,继服14剂而诸症悉平,日后已能自操家务。
Claims (5)
1.一种用于心衰治疗的中药配方,其特征在于:该中药配方按重量份数包括以下中药成分:老茶树根24g,万年青根11g,丹参24g,党参24g,桂枝16g,炒白芍16g,泽泻28g,瓜蒌皮24g,薤白头13g,炙甘草16g。
2.如权利要求1所述的用于心衰治疗的中药配方,其特征在于:该中药配方还包括茯苓皮16g,生姜皮11g,葶苈子13g。
3.如权利要求1所述的用于心衰治疗的中药配方,其特征在于:该中药配方还包括麻黄16g,苏梗13g,杏仁16g。
4.如权利要求1所述的用于心衰治疗的中药配方,其特征在于:该中药配方还包括旋复花13g,降香16g,橘红络16g。
5.如权利要求1所述的用于心衰治疗的中药配方的制备方法,其特征在于:先将药材放入砂锅中用冷水浸泡小时,浸泡的水量以淹没药面3cm为宜,将药放在火上,用武火熬开,沸腾后改用文火保持微沸状态,第一次煎煮50分钟,将药液倒出,第二次煎煮加入以刚淹没药渣2-3cm的热水,煎煮30分钟,将药液倒出,将2次药液混合为1剂,每天1剂,分早晚温服。
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