CN107996936A - 一种可改善胃部健康问题的固体饮料 - Google Patents
一种可改善胃部健康问题的固体饮料 Download PDFInfo
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Abstract
本发明公开了一种可改善胃部健康问题的固体饮料,所述固体饮料包含发酵大豆粉、碳酸钙和益生菌,所述益生菌包括瑞士乳杆菌和鼠李糖乳杆菌,所述固体饮料还包含木糖醇和麦芽糊精,所述发酵大豆粉为大豆经菌株德氏乳杆菌乳亚种Rosell‑187发酵制得,该固体饮料为粉末状,使用时直接倒入口中,用水送服,本发明全部使用食品原料,安全、有效、无任何副作用;可改善溃疡引起的胃痛、胃酸过多和胃灼热等胃部健康问题;可以改善人体微生物菌群平衡,缓解因使用杀菌药物或抗生素带来的副作用,如抗生素相关腹泻等。
Description
技术领域
本发明涉及一种益生菌类固体饮料,特别涉及一种可改善胃部健康问题的固体饮料。
背景技术
对于胃痛、胃酸过多等常见的症状,常用的方法多为服用一些止痛药物、解痉挛药物或一些中和胃酸、抑制胃酸分泌的药物。快速地中和胃酸或抑制胃酸分泌,大幅度地改变胃中胃酸水平,进而减少胃酸对胃壁的刺激,暂时缓解胃部不适。
上述方法虽然可以暂时缓解胃痛、胃酸过多等症状,但在随后一段时间内,会引起机体反射性地增加胃酸分泌,加重胃酸过多、胃痛等症状,进而需继续加大剂量进行服用,形成恶性循环,无法从根本上有效改善胃粘膜健康状况,更有甚者会引起一系列副作用。
幽门螺旋杆菌,是一种革兰氏阴性菌,主要分布在胃粘膜组织中,67%-80%的胃溃疡和95%的十二指肠溃疡是由幽门螺旋杆菌引起的。在治疗幽门螺杆菌感染时,一般会使用大量的抗菌药物或抗生素,但是大量使用抗菌药物或抗生素会带来一些副作用或不良影响,如肠道功能紊乱、肠道菌群失调、胃部不适、抗生素相关腹泻、过敏等。原因在于在杀灭幽门螺杆菌的同时,也杀灭了人体必需的一些微生物,造成了人体微生物菌群的失调,尤其是肠道菌群的失调,从而会引起一系列因菌群失调带来的健康问题。
发明内容
为解决上述技术问题,本发明提供了一种可改善胃部健康问题的固体饮料,旨在使用发酵大豆粉,改善胃粘膜健康问题,缓解因胃粘膜健康问题引起的胃痛、反酸、胃灼热等症状;改善胃溃疡与十二指肠溃疡相关的症状,缓解因溃疡造成的身体不适感,提高患者的生活质量;配合常规治疗,改善溃疡疾病的治疗效果。同时,对于引起胃部疾病的常见致病菌——幽门螺杆菌,现代医学会采用抗菌药物或抗生素进行治疗,本发明中选择使用益生菌原料,可以缓解因服用杀菌药物或抗生素带来的副作用或不良影响,在治疗幽门螺杆菌感染的同时,调理机体的微生态的整体平衡。
为达到上述目的,本发明的技术方案如下:
一种可改善胃部健康问题的固体饮料,包含发酵大豆粉、碳酸钙和益生菌,所述益生菌包括瑞士乳杆菌和鼠李糖乳杆菌。
上述方案中,所述固体饮料还包含木糖醇和麦芽糊精。
上述方案中,每1g固体饮料中包含发酵大豆粉0.5g、碳酸钙40mg、益生菌66.7mg、木糖醇200mg、剩余为麦芽糊精。
进一步地,所述发酵大豆粉为大豆经菌株德氏乳杆菌乳亚种Rosell-187发酵制得。
上述方案中,所述益生菌具体菌株为瑞士乳杆菌Lafti L10、瑞士乳杆菌Rosell-52、鼠李糖乳杆菌Rosell-11。
上述方案中,每1g固体饮料中包含瑞士乳杆菌共22亿CFU、鼠李糖乳杆菌78亿CFU,其中包括15亿CFU瑞士乳杆菌Lafti L10和7亿CFU瑞士乳杆菌Rosell-52。
上述方案中,所述固体饮料为粉末状,使用时直接倒入口中,用水送服。
通过上述技术方案,本发明提供的可改善胃部健康问题的固体饮料具有以下有益效果:
1、选择具有独特功能的发酵大豆粉,使用德氏乳杆菌乳亚种Rosell-187菌株,运用发酵技术对大豆进行发酵,得到发酵大豆粉。全部使用食品原料,采用一种绿色健康的方法,有效改善胃部不适症状;安全、有效、无任何副作用、受众广泛、应用简单。
2、选择具有充分研究支持的益生菌产品,经科学组合,作用于人体;改善人体微生物菌群平衡,缓解因使用杀菌药物或抗生素带来的副作用。
3、经多项科学研究证明,本发明中所选择的产品,能够有效改善胃部健康问题,如溃疡引起的胃痛、胃酸过多、胃灼热等。
具体实施方式
下面将对本发明实施例中的技术方案进行清楚、完整地描述。
本发明提供了一种可改善胃部健康问题的固体饮料,具体实施例如下:
该固体饮料每份1g,包括发酵大豆粉0.5g、碳酸钙40mg、益生菌66.7mg,200mg木糖醇作为甜味剂,剩余重量使用麦芽糊精填充。
其中,益生菌活菌数为100亿CFU/份,瑞士乳杆菌共22亿CFU(15亿CFU瑞士乳杆菌Lafti L10和7亿CFU瑞士乳杆菌Rosell-52)、鼠李糖乳杆菌78亿CFU。
发酵大豆粉来自加拿大拉曼保健科技有限公司(以下简称拉曼公司),具体品牌为Gastro-AD,为大豆经拉曼公司特有菌株德氏乳杆菌乳亚种Rosell-187使用特有工艺发酵制得。
益生菌产品均来自加拿大拉曼公司,具体菌株为瑞士乳杆菌Lafti L10、瑞士乳杆菌Rosell-52、鼠李糖乳杆菌Rosell-11。
所有原料混合均匀后得到粉状产品,使用时直接倒入口中,用水送服。
人体试验一:
试验过程:选择患有胃部不适症状的人群,使用本发明的产品进行日常服用,调研胃部不适症状的改善情况。
受试对象:12位患有胃炎或其他胃肠道疾病的人员(22-75岁),主要症状为缺乏食欲、反胃、胃痛、烧心。
试验方法:
在试验开始前,对缺乏食欲、胃痛、烧心、反胃、呕吐各症状进行人数统计,统计出每种症状各有多少人数。
·所有受试者每日服用本发明中的产品1份/次,2次/日,服用时将产品直接倒入口中,以温水送服。
·使用本发明中产品共30天。
·30天后,对缺乏食欲、胃痛、烧心、反胃、呕吐各症状进行人数统计,统计出每种症状各有多少人数。
表1试验前后各症状的人数统计
症状 | 试验前人数 | 试验后人数 |
缺乏食欲 | 6 | 1 |
胃痛 | 12 | 5 |
烧心 | 7 | 1 |
反胃 | 5 | 3 |
呕吐 | 2 | 1 |
由上表结果可见,在服用本发明中产品30天后,各种胃部不适症状的人数均有所减少,说明本发明中的产品可有效改善胃部不适症状。
人体试验二:
试验过程:选择长期服用抗生素并造成抗生素相关腹泻的人群,使用本发明者的产品进行日常服用,调研腹泻症状的改善情况。
受试对象:200名因长期服用抗生素造成抗生素相关腹泻的人员(3-12岁),主要症状为每日2-3次或更高频率腹泻,连续多日发病,使用常规抗生素治疗无明显改善。
试验方法:
·将所有受试者分为两组,分别为对照组与实验组。
·对照组经诊断为抗生素相关腹泻后,通过常规治疗手段进行治疗,如停用抗生素或调整抗生素用药种类等。
·实验组在使用常规治疗手段的同时,配合使用本发明中的产品,服用量为1份/次,2次/日。若试验期间仍在服用抗生素,则本发明中的产品与抗生素的服用时间至少间隔2小时。
·试验持续3周,试验结束后,统计所有受试者试验期间平均腹泻的持续时间。
表2对照组与试验组在试验期内平均腹泻的持续时间(天)
对照组 | 试验组 | |
平均腹泻持续时间 | 6天 | 3.5天 |
由上表结果可见,在服用本发明中产品后,可有效减少腹泻天数,对肠道健康具有积极的效果。
综上,由上述所有结果可看出,本发明中的产品在改善各种胃部不适症状的同时,还能有效改善肠道不适症状,如腹泻。
本发明中涉及到的发酵大豆粉,能够有效改善因胃酸过多、胃粘膜健康方面引起的多种胃部不适症状,具体的原理在于:
1、在摄入本发明中的产品后,会以人体自然消化的方式,在机体正常范围内临时性地缓冲胃酸,从而快速缓解患者的烧心和胃部灼烧感。
2、另外,由于胃酸和蛋白酶在其行使活性过程中无“特定性”,当粘膜屏障改变时,胃壁肌肉组织暴露在胃液中,胃中的消化液会对胃壁进行降解。
本发明中的产品,预降解了大豆蛋白,释放出“活性”抑制肽(抗营养化因子)。这种肽可以临时性“封闭”胃蛋白酶的活性位点,从而临时性抑制了酶的活性,进而缓解了胃壁被降解的情况。
3、本发明中的产品还能够调节机体的免疫水平,增加胃粘膜上粘液的分泌。加强粘液对胃粘膜的屏障保护,进而避免胃酸和胃中的蛋白酶对胃壁的刺激和“消化降解”。
益生菌的作用机理在于以下几个方面:
1、产生致病菌抑制物,如乳酸、细菌素、过氧化氢、乙酸等,抑制致病菌的生长;
2、抑制致病菌附着:与致病菌竞争人体上皮细胞的粘附位点,减少致病菌在人体的定植;
3、调节免疫系统:通过细胞间的交流,调节机体白细胞介素等细胞因子,从而调节机体免疫;
4、特定的代谢活性:益生菌能分解微生物毒素、分解乳糖等,从而减少此类物质对机体的危害。
碳酸钙可以起到辅助缓冲胃酸的作用,用量很少,在发酵大豆粉以消化的形式缓冲胃酸的过程中,加少量碳酸钙,直接地缓冲胃酸,可以改善溃疡引起的疼痛,也能改善胃部的灼热感,溃疡引起的胃痛主要是因为胃酸太多,刺激溃疡面造成,胃灼热也多是因为胃酸太多,从而胃部感觉灼热,因此,在机体可接受范围内适当缓冲胃酸,可改善因胃酸过多引起的胃部不适。
对所公开的实施例的上述说明,使本领域专业技术人员能够实现或使用本发明。对这些实施例的多种修改对本领域的专业技术人员来说将是显而易见的,本文中所定义的一般原理可以在不脱离本发明的精神或范围的情况下,在其它实施例中实现。因此,本发明将不会被限制于本文所示的这些实施例,而是要符合与本文所公开的原理和新颖特点相一致的最宽的范围。
Claims (7)
1.一种可改善胃部健康问题的固体饮料,其特征在于,所述固体饮料包含发酵大豆粉、碳酸钙和益生菌,所述益生菌包括瑞士乳杆菌和鼠李糖乳杆菌。
2.根据权利要求1所述的一种可改善胃部健康问题的固体饮料,其特征在于,所述固体饮料还包含木糖醇和麦芽糊精。
3.根据权利要求2所述的一种可改善胃部健康问题的固体饮料,其特征在于,每1g固体饮料中包含发酵大豆粉0.5g、碳酸钙40mg、益生菌66.7mg、木糖醇200mg、剩余为麦芽糊精。
4.根据权利要求1所述的一种可改善胃部健康问题的固体饮料,其特征在于,所述发酵大豆粉为大豆经菌株德氏乳杆菌乳亚种Rosell-187发酵制得。
5.根据权利要求1所述的一种可改善胃部健康问题的固体饮料,其特征在于,所述益生菌具体菌株为瑞士乳杆菌Lafti L10、瑞士乳杆菌Rosell-52、鼠李糖乳杆菌Rosell-11。
6.根据权利要求5所述的一种可改善胃部健康问题的固体饮料,其特征在于,每1g固体饮料中包含瑞士乳杆菌共22亿CFU、鼠李糖乳杆菌78亿CFU,其中包括15亿CFU瑞士乳杆菌Lafti L10和7亿CFU瑞士乳杆菌Rosell-52。
7.根据权利要求1所述的一种可改善胃部健康问题的固体饮料,其特征在于,所述固体饮料为粉末状,使用时直接倒入口中,用水送服。
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