CN107949379A - L‑4‑氯代犬尿氨酸的治疗用途 - Google Patents
L‑4‑氯代犬尿氨酸的治疗用途 Download PDFInfo
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Classifications
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
- A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Diabetes (AREA)
- Epidemiology (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Obesity (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562179924P | 2015-05-22 | 2015-05-22 | |
| US62/179,924 | 2015-05-22 | ||
| PCT/US2016/033733 WO2016191351A1 (en) | 2015-05-22 | 2016-05-23 | Therapeutic uses of l-4-chlorokynurenine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107949379A true CN107949379A (zh) | 2018-04-20 |
Family
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
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| CN201680042400.6A Pending CN107949379A (zh) | 2015-05-22 | 2016-05-23 | L‑4‑氯代犬尿氨酸的治疗用途 |
Country Status (19)
| Country | Link |
|---|---|
| US (3) | US20180140568A1 (https=) |
| EP (2) | EP4108239A1 (https=) |
| JP (3) | JP2018521007A (https=) |
| KR (2) | KR20180015158A (https=) |
| CN (1) | CN107949379A (https=) |
| AU (3) | AU2016268153B2 (https=) |
| BR (1) | BR112017024908A2 (https=) |
| CA (1) | CA3024783A1 (https=) |
| DK (1) | DK3297619T3 (https=) |
| EA (1) | EA201792571A1 (https=) |
| ES (1) | ES2925274T3 (https=) |
| IL (3) | IL296380A (https=) |
| MX (1) | MX395492B (https=) |
| PL (1) | PL3297619T3 (https=) |
| PT (1) | PT3297619T (https=) |
| SG (1) | SG10202007661XA (https=) |
| SI (1) | SI3297619T1 (https=) |
| WO (1) | WO2016191351A1 (https=) |
| ZA (1) | ZA201707874B (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115677519A (zh) * | 2021-07-22 | 2023-02-03 | 立科时代(武汉)生物科技有限公司 | L-4-溴-犬尿氨酸及其在制备治疗抑郁症药物中的应用 |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PT3598971T (pt) | 2013-01-22 | 2024-06-20 | Vistagen Therapeutics Inc | ¿formas de dosagem e utilizações terapêuticas de l-4 cloroquinurenina |
| US20210393621A1 (en) | 2018-10-26 | 2021-12-23 | The Research Foundation For The State University Of New York | Combination serotonin specific reuptake inhibitor and serotonin 1a receptor partial agonist for reducing l-dopa-induced dyskinesia |
| CA3136418A1 (en) * | 2019-04-09 | 2020-10-15 | Vistagen Therapeutics, Inc. | Genetic variants associated with response to treatment of neurological disorders |
| JP7805969B2 (ja) * | 2020-06-24 | 2026-01-26 | バイオヘイブン・セラピューティクス・リミテッド | 強迫性障害を治療するための組成物及び方法 |
| WO2022221423A1 (en) * | 2021-04-13 | 2022-10-20 | Vistagen Therapeutics, Inc. | Treatment of autoimmune anti-nmda-receptor encephalitis |
| WO2024011105A1 (en) * | 2022-07-05 | 2024-01-11 | Mahana Therapeutics, Inc. | Methods and systems for treating tinnitus using digital therapeutics |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20010011095A1 (en) * | 1998-03-09 | 2001-08-02 | The Trustees Of Tufts College Ballou Hall | Treatment of stereotypic, self-injurious and compulsive behaviors in man and animals using antagonists of NMDA receptors |
| WO2014116739A1 (en) * | 2013-01-22 | 2014-07-31 | Vistagen Therapeutics, Inc. | Dosage forms and therapeutic uses l-4-chlorokynurenine |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
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| US5484814A (en) | 1991-02-28 | 1996-01-16 | Merrell Dow Pharmaceuticals Inc. | NMDA antagonists |
| TW518218B (en) * | 1999-05-27 | 2003-01-21 | Merck Patent Gmbh | Pharmaceutical compositions comprising 1-[4-(5-cyanoindol-3-yl)butyl]-4-(2-carbamoylbenzofuran-5-yl)piperazine or its physiologically acceptable salts for use in the treatment of sub-type anxiety disorders |
| CN1486180A (zh) * | 2000-12-07 | 2004-03-31 | 纽热莫勒丘乐有限公司 | 用nmda受体拮抗物治疗神经精神病紊乱的方法 |
| US20060063802A1 (en) * | 2004-03-29 | 2006-03-23 | Matthieu Guitton | Methods for the treatment of tinnitus induced by cochlear excitotoxicity |
| AU2007235876A1 (en) * | 2006-04-12 | 2007-10-18 | Probiodrug Ag | Enzyme inhibitors |
| US8058243B2 (en) * | 2006-10-13 | 2011-11-15 | Hsc Research And Development Limited Partnership | Method for treating a brain cancer with ifenprodil |
| WO2009061935A2 (en) * | 2007-11-06 | 2009-05-14 | Emory University | Methods of identifying safe nmda receptor antagonists |
| TW201026667A (en) * | 2008-09-30 | 2010-07-16 | Merz Pharma Gmbh & Co Kgaa | Glycine b antagonists |
| KR20150096370A (ko) * | 2012-08-23 | 2015-08-24 | 스튜어트 엘. 웨그 | 항불안제 조성물, 제형 및 사용방법 |
| WO2014152835A1 (en) | 2013-03-14 | 2014-09-25 | Vistagen Therapeutics, Inc. | Synthesis of chiral kynurenine compounds and intermediates |
| CN107417558A (zh) | 2013-03-14 | 2017-12-01 | 维斯塔津治疗公司 | 用于合成手性犬尿氨酸化合物的方法 |
| KR20170013890A (ko) * | 2014-05-06 | 2017-02-07 | 노쓰웨스턴유니버시티 | Nmdar 조절 화합물의 조합물 |
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2016
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- 2016-05-23 EA EA201792571A patent/EA201792571A1/ru unknown
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2017
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2019
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2021
- 2021-07-29 AU AU2021209279A patent/AU2021209279B2/en active Active
- 2021-08-25 IL IL285882A patent/IL285882A/en unknown
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2022
- 2022-01-17 JP JP2022004811A patent/JP2022064908A/ja active Pending
- 2022-09-30 US US17/958,169 patent/US20240122887A1/en not_active Abandoned
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2023
- 2023-12-13 AU AU2023282234A patent/AU2023282234A1/en not_active Abandoned
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2024
- 2024-01-04 JP JP2024000227A patent/JP2024050575A/ja active Pending
Patent Citations (2)
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| US20010011095A1 (en) * | 1998-03-09 | 2001-08-02 | The Trustees Of Tufts College Ballou Hall | Treatment of stereotypic, self-injurious and compulsive behaviors in man and animals using antagonists of NMDA receptors |
| WO2014116739A1 (en) * | 2013-01-22 | 2014-07-31 | Vistagen Therapeutics, Inc. | Dosage forms and therapeutic uses l-4-chlorokynurenine |
Non-Patent Citations (4)
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| MATTHIEU J. GUITTON等: "HORT COMMUNICATION m-Chlorophenylpiperazine exacerbates perception of salicylate-induced tinnitus in rats", 《EUROPEAN JOURNAL OF NEUROSCIENCE》 * |
| 何敏 等: "《大学生心理健康教育》", 31 August 2014, 西南交通大学出版社 * |
| 无: "istagen Therapeutics Successfully Completes Final Phase 1 Safety Study of AV-101", 《HTTPS://WWW.VISTAGEN.COM/NEWS-MEDIA/PRESS-RELEASES/DETAIL/12/VISTAGEN-THERAPEUTICS-SUCCESSFULLY-COMPLETES-FINAL-PHASE-1》 * |
| 无: "VistaGen and NIH Sign Agreement for NIH-Sponsored Phase 2 Study of Orally-Active AV-101 in Major Depressive Disorder", 《HTTPS://WWW.VISTAGEN.COM/NEWS-MEDIA/PRESS-RELEASES/DETAIL/40/VISTAGEN-AND-NIH-SIGN-AGREEMENT-FOR-NIH-SPONSORED-PHASE-2》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115677519A (zh) * | 2021-07-22 | 2023-02-03 | 立科时代(武汉)生物科技有限公司 | L-4-溴-犬尿氨酸及其在制备治疗抑郁症药物中的应用 |
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Application publication date: 20180420 |