PT3598971T - ¿formas de dosagem e utilizações terapêuticas de l-4 cloroquinurenina - Google Patents

¿formas de dosagem e utilizações terapêuticas de l-4 cloroquinurenina

Info

Publication number
PT3598971T
PT3598971T PT191963669T PT19196366T PT3598971T PT 3598971 T PT3598971 T PT 3598971T PT 191963669 T PT191963669 T PT 191963669T PT 19196366 T PT19196366 T PT 19196366T PT 3598971 T PT3598971 T PT 3598971T
Authority
PT
Portugal
Prior art keywords
chlorokynurenine
dosage forms
therapeutic uses
therapeutic
dosage
Prior art date
Application number
PT191963669T
Other languages
English (en)
Original Assignee
Vistagen Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vistagen Therapeutics Inc filed Critical Vistagen Therapeutics Inc
Publication of PT3598971T publication Critical patent/PT3598971T/pt

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/14Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
    • A61P25/16Anti-Parkinson drugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Pain & Pain Management (AREA)
  • Psychology (AREA)
  • Psychiatry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Quinoline Compounds (AREA)
  • Cosmetics (AREA)
  • Lubricants (AREA)
PT191963669T 2013-01-22 2014-01-22 ¿formas de dosagem e utilizações terapêuticas de l-4 cloroquinurenina PT3598971T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201361849191P 2013-01-22 2013-01-22

Publications (1)

Publication Number Publication Date
PT3598971T true PT3598971T (pt) 2024-06-20

Family

ID=51228003

Family Applications (3)

Application Number Title Priority Date Filing Date
PT171700792T PT3228313T (pt) 2013-01-22 2014-01-22 Formas de dosagem e utilizações terapêuticas de l-4-cloroquinurenina
PT147435705T PT2948140T (pt) 2013-01-22 2014-01-22 Formas de dosagem e utilizações terapêuticas de l-4-cloroquinurenina
PT191963669T PT3598971T (pt) 2013-01-22 2014-01-22 ¿formas de dosagem e utilizações terapêuticas de l-4 cloroquinurenina

Family Applications Before (2)

Application Number Title Priority Date Filing Date
PT171700792T PT3228313T (pt) 2013-01-22 2014-01-22 Formas de dosagem e utilizações terapêuticas de l-4-cloroquinurenina
PT147435705T PT2948140T (pt) 2013-01-22 2014-01-22 Formas de dosagem e utilizações terapêuticas de l-4-cloroquinurenina

Country Status (22)

Country Link
US (7) US9993450B2 (pt)
EP (4) EP4385563A3 (pt)
JP (5) JP6436913B2 (pt)
KR (5) KR102257284B1 (pt)
CN (4) CN113116877A (pt)
AU (4) AU2014209466B2 (pt)
BR (1) BR112015017535A2 (pt)
CA (3) CA3128321C (pt)
CY (1) CY1122403T1 (pt)
DK (3) DK3598971T3 (pt)
ES (3) ES2635353T3 (pt)
HK (1) HK1217170A1 (pt)
HR (2) HRP20240812T1 (pt)
HU (1) HUE067381T2 (pt)
IL (3) IL291831A (pt)
MX (2) MX2015009277A (pt)
PL (2) PL3598971T3 (pt)
PT (3) PT3228313T (pt)
RS (1) RS59687B1 (pt)
SI (2) SI3228313T1 (pt)
WO (1) WO2014116739A1 (pt)
ZA (2) ZA201505569B (pt)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP6436913B2 (ja) 2013-01-22 2018-12-12 ヴィスタゲン セラピューティクス、インコーポレイテッド L−4−クロロキヌレニンの剤形及び治療的使用
AU2016268153B2 (en) * 2015-05-22 2021-08-12 Vistagen Therapeutics, Inc. Therapeutic uses of L-4-chlorokynurenine
WO2017044516A1 (en) * 2015-09-08 2017-03-16 Cephalon, Inc. Prodrugs of chlorokynurenines
CN118026866A (zh) 2018-02-09 2024-05-14 维斯塔津治疗公司 4-氯代犬尿氨酸及中间体的合成
CN109223785A (zh) * 2018-10-29 2019-01-18 中国药科大学 犬尿喹啉酸或其衍生物在制备改善慢性精神应激相关病理损伤药物中的应用
WO2022082100A1 (en) * 2020-10-16 2022-04-21 Vistagen Therapeutics, Inc. Cocrystals of l-4-chlorokynurenine, compositions and therapeutic uses thereof

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US5086072A (en) * 1990-06-18 1992-02-04 The United States Of America As Represented By The Department Of Health And Human Services Treatment of mood disorders with functional antagonists of the glycine/nmda receptor complex
US5360814A (en) 1991-02-28 1994-11-01 Merrell Dow Pharmaceuticals Inc. NMDA antagonists
US5484814A (en) 1991-02-28 1996-01-16 Merrell Dow Pharmaceuticals Inc. NMDA antagonists
US5763393A (en) 1996-05-17 1998-06-09 Neurotherapeutics L.P. Neuroactive peptides
TW518218B (en) 1999-05-27 2003-01-21 Merck Patent Gmbh Pharmaceutical compositions comprising 1-[4-(5-cyanoindol-3-yl)butyl]-4-(2-carbamoylbenzofuran-5-yl)piperazine or its physiologically acceptable salts for use in the treatment of sub-type anxiety disorders
WO2003015713A2 (en) 2001-08-20 2003-02-27 Maiken Nedergaard Treatment of glial tumors with glutamate antagonists
WO2004022069A1 (en) 2002-09-06 2004-03-18 Durect Corporation Delivery of modulators of glutamate-mediated neurotransmission to the inner ear
US20060063802A1 (en) 2004-03-29 2006-03-23 Matthieu Guitton Methods for the treatment of tinnitus induced by cochlear excitotoxicity
BRPI0709984A2 (pt) 2006-04-12 2011-08-02 Probiodrug Ag inibidores de enzima
EP1903028A1 (en) * 2006-09-22 2008-03-26 Werner Tschollar Conjugates of glutamate and NMDA receptor channel blockers without excito-toxic effects
CA2606658A1 (en) 2006-10-13 2008-04-13 Mike Tyers Compositions and methods for treating neurological disorders or damage
DK2142514T3 (da) 2007-04-18 2015-03-23 Probiodrug Ag Thioureaderivater som glutaminylcyclase-inhibitorer
WO2009135091A1 (en) * 2008-04-30 2009-11-05 Medivation Technologies, Inc. Use of asenapine and related compounds for the treatment of neuronal or non-neuronal diseases or conditions
WO2010022300A1 (en) * 2008-08-21 2010-02-25 Forest Laboratories Holdings Limited Methods for treating neuropathic pain
EP2421519B1 (en) 2009-04-23 2016-11-02 Universität Zürich Blockers of nmda receptor for the treatment of sickle cell anemia
WO2010147938A2 (en) * 2009-06-17 2010-12-23 Targacept, Inc. Reversal of l-dopa-induced dyskinesia by neuronal nicotinic receptor ligands
CN104777314B (zh) 2009-08-12 2017-01-04 福满代谢组技术有限公司 抑郁症的生物标记物、抑郁症的生物标记物的测定方法、计算机程序及记录介质
US8951968B2 (en) 2009-10-05 2015-02-10 Northwestern University Methods of treating depression and other related diseases
EP2338873A1 (en) * 2009-12-22 2011-06-29 Gmeiner, Peter New aminotetraline derivatives
DK2582366T3 (en) * 2010-06-15 2015-12-07 Gruenenthal Gmbh A pharmaceutical combination for the treatment of pain.
US9737531B2 (en) 2012-07-12 2017-08-22 Glytech, Llc Composition and method for treatment of depression and psychosis in humans
JP6436913B2 (ja) 2013-01-22 2018-12-12 ヴィスタゲン セラピューティクス、インコーポレイテッド L−4−クロロキヌレニンの剤形及び治療的使用
CN105164096A (zh) 2013-03-14 2015-12-16 维斯塔津治疗公司 手性犬尿氨酸化合物和中间体的合成
BR112016009443A8 (pt) 2013-10-28 2020-03-24 Naurex Inc moduladores do receptor de nmda, pró-drogas e seus sais
AU2016268153B2 (en) 2015-05-22 2021-08-12 Vistagen Therapeutics, Inc. Therapeutic uses of L-4-chlorokynurenine

Also Published As

Publication number Publication date
AU2014209466B2 (en) 2018-11-08
AU2022221382B2 (en) 2024-09-19
DK3598971T3 (da) 2024-06-10
EP2948140A4 (en) 2016-08-03
IL240090A0 (en) 2015-09-24
ES2751138T3 (es) 2020-03-30
PT2948140T (pt) 2017-08-10
KR20230003410A (ko) 2023-01-05
US20180369180A1 (en) 2018-12-27
HRP20240812T1 (hr) 2024-09-27
EP3598971A1 (en) 2020-01-29
RS59687B1 (sr) 2020-01-31
ZA201505569B (en) 2017-01-25
JP2020183400A (ja) 2020-11-12
IL276126A (en) 2020-08-31
US20180289649A1 (en) 2018-10-11
KR20150109428A (ko) 2015-10-01
CN113116877A (zh) 2021-07-16
KR102257284B1 (ko) 2021-05-28
US20150359772A1 (en) 2015-12-17
KR20230098711A (ko) 2023-07-04
PL3228313T3 (pl) 2020-03-31
EP3228313A1 (en) 2017-10-11
MX2020009966A (es) 2020-10-12
PT3228313T (pt) 2019-12-17
US10980758B2 (en) 2021-04-20
US9993450B2 (en) 2018-06-12
JP6436913B2 (ja) 2018-12-12
KR102335919B1 (ko) 2021-12-07
JP7021298B2 (ja) 2022-02-16
US20190125707A1 (en) 2019-05-02
PL3598971T3 (pl) 2024-09-09
CN113209068A (zh) 2021-08-06
EP3228313B1 (en) 2019-09-11
AU2022221382A1 (en) 2022-09-15
EP4385563A3 (en) 2024-08-21
DK3228313T3 (da) 2019-11-25
BR112015017535A2 (pt) 2020-02-04
US20220409564A1 (en) 2022-12-29
CA2898619A1 (en) 2014-07-31
EP2948140B1 (en) 2017-05-10
KR20210063449A (ko) 2021-06-01
CN105073108A (zh) 2015-11-18
DK2948140T3 (en) 2017-08-21
HUE067381T2 (hu) 2024-10-28
US10632091B2 (en) 2020-04-28
EP4385563A2 (en) 2024-06-19
US10617663B2 (en) 2020-04-14
ES2980120T3 (es) 2024-09-30
EP2948140A1 (en) 2015-12-02
CA3128321A1 (en) 2014-07-31
US20160158178A1 (en) 2016-06-09
IL240090B (en) 2020-08-31
CY1122403T1 (el) 2021-01-27
NZ710121A (en) 2021-01-29
AU2014209466A1 (en) 2015-08-06
CN112933073A (zh) 2021-06-11
EP3598971B1 (en) 2024-03-20
IL276126B (en) 2022-05-01
JP2019023195A (ja) 2019-02-14
SI3228313T1 (sl) 2019-12-31
AU2018253600A1 (en) 2018-11-22
IL291831A (en) 2022-06-01
US12036198B2 (en) 2024-07-16
ES2635353T3 (es) 2017-10-03
AU2020204420A1 (en) 2020-07-23
US20190133984A1 (en) 2019-05-09
KR20210149905A (ko) 2021-12-09
JP2022070894A (ja) 2022-05-13
HRP20192189T1 (hr) 2020-02-21
ZA201607581B (en) 2019-04-24
CA3128321C (en) 2023-12-05
US9993453B2 (en) 2018-06-12
JP6804497B2 (ja) 2020-12-23
AU2018253600B2 (en) 2020-07-09
CA3216579A1 (en) 2014-07-31
CA2898619C (en) 2021-10-19
HK1217170A1 (zh) 2016-12-30
WO2014116739A1 (en) 2014-07-31
MX2015009277A (es) 2015-12-11
JP2016505050A (ja) 2016-02-18
JP2024069257A (ja) 2024-05-21
SI3598971T1 (sl) 2024-10-30

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