RS59687B1 - Oblici doziranja i terapeutske primene l-4-hlorkinurenina - Google Patents
Oblici doziranja i terapeutske primene l-4-hlorkinureninaInfo
- Publication number
- RS59687B1 RS59687B1 RS20191519A RSP20191519A RS59687B1 RS 59687 B1 RS59687 B1 RS 59687B1 RS 20191519 A RS20191519 A RS 20191519A RS P20191519 A RSP20191519 A RS P20191519A RS 59687 B1 RS59687 B1 RS 59687B1
- Authority
- RS
- Serbia
- Prior art keywords
- chlorokynurenine
- dosage forms
- therapeutic uses
- therapeutic
- dosage
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
- A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid, pantothenic acid
- A61K31/198—Alpha-aminoacids, e.g. alanine, edetic acids [EDTA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201361849191P | 2013-01-22 | 2013-01-22 | |
| EP17170079.2A EP3228313B1 (en) | 2013-01-22 | 2014-01-22 | Dosage forms and therapeutic uses of l-4-chlorokynurenine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RS59687B1 true RS59687B1 (sr) | 2020-01-31 |
Family
ID=51228003
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RS20191519A RS59687B1 (sr) | 2013-01-22 | 2014-01-22 | Oblici doziranja i terapeutske primene l-4-hlorkinurenina |
Country Status (21)
| Country | Link |
|---|---|
| US (7) | US9993450B2 (sr) |
| EP (3) | EP3228313B1 (sr) |
| JP (4) | JP6436913B2 (sr) |
| KR (5) | KR20230098711A (sr) |
| CN (4) | CN112933073A (sr) |
| AU (4) | AU2014209466B2 (sr) |
| BR (1) | BR112015017535A2 (sr) |
| CA (3) | CA2898619C (sr) |
| CY (1) | CY1122403T1 (sr) |
| DK (2) | DK3228313T3 (sr) |
| ES (2) | ES2751138T3 (sr) |
| HK (1) | HK1217170A1 (sr) |
| HR (1) | HRP20192189T1 (sr) |
| IL (3) | IL291831A (sr) |
| MX (2) | MX2015009277A (sr) |
| PL (1) | PL3228313T3 (sr) |
| PT (2) | PT3228313T (sr) |
| RS (1) | RS59687B1 (sr) |
| SI (1) | SI3228313T1 (sr) |
| WO (1) | WO2014116739A1 (sr) |
| ZA (2) | ZA201505569B (sr) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112933073A (zh) | 2013-01-22 | 2021-06-11 | 维斯塔津治疗公司 | L-4-氯犬尿氨酸的剂型和治疗用途 |
| EA201792571A1 (ru) * | 2015-05-22 | 2018-06-29 | Вистаджен Терапьютикс, Инк. | Терапевтическое применение l-4-хлорокинуренина |
| EP3347346A1 (en) * | 2015-09-08 | 2018-07-18 | Cephalon, Inc. | Prodrugs of chlorokynurenines |
| WO2019157426A1 (en) | 2018-02-09 | 2019-08-15 | Vistagen Therapeutics, Inc. | Synthesis of 4-chlorokynurenines and intermediates |
| CN109223785A (zh) * | 2018-10-29 | 2019-01-18 | 中国药科大学 | 犬尿喹啉酸或其衍生物在制备改善慢性精神应激相关病理损伤药物中的应用 |
| WO2022082100A1 (en) * | 2020-10-16 | 2022-04-21 | Vistagen Therapeutics, Inc. | Cocrystals of l-4-chlorokynurenine, compositions and therapeutic uses thereof |
Family Cites Families (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5086072A (en) * | 1990-06-18 | 1992-02-04 | The United States Of America As Represented By The Department Of Health And Human Services | Treatment of mood disorders with functional antagonists of the glycine/nmda receptor complex |
| US5484814A (en) | 1991-02-28 | 1996-01-16 | Merrell Dow Pharmaceuticals Inc. | NMDA antagonists |
| US5360814A (en) | 1991-02-28 | 1994-11-01 | Merrell Dow Pharmaceuticals Inc. | NMDA antagonists |
| US5763393A (en) | 1996-05-17 | 1998-06-09 | Neurotherapeutics L.P. | Neuroactive peptides |
| TW518218B (en) | 1999-05-27 | 2003-01-21 | Merck Patent Gmbh | Pharmaceutical compositions comprising 1-[4-(5-cyanoindol-3-yl)butyl]-4-(2-carbamoylbenzofuran-5-yl)piperazine or its physiologically acceptable salts for use in the treatment of sub-type anxiety disorders |
| US7250394B2 (en) | 2001-08-20 | 2007-07-31 | Maiken Nedergaard | Treatment of glial tumors with glutamate antagonists |
| JP2006502158A (ja) | 2002-09-06 | 2006-01-19 | デュレクト コーポレーション | グルタメート媒介神経伝達のモジュレーターの内耳への送達 |
| US20060063802A1 (en) | 2004-03-29 | 2006-03-23 | Matthieu Guitton | Methods for the treatment of tinnitus induced by cochlear excitotoxicity |
| JP2009533393A (ja) | 2006-04-12 | 2009-09-17 | プロビオドルグ エージー | 酵素阻害薬 |
| EP1903028A1 (en) * | 2006-09-22 | 2008-03-26 | Werner Tschollar | Conjugates of glutamate and NMDA receptor channel blockers without excito-toxic effects |
| US8058243B2 (en) | 2006-10-13 | 2011-11-15 | Hsc Research And Development Limited Partnership | Method for treating a brain cancer with ifenprodil |
| DK2142514T3 (da) | 2007-04-18 | 2015-03-23 | Probiodrug Ag | Thioureaderivater som glutaminylcyclase-inhibitorer |
| WO2009135091A1 (en) * | 2008-04-30 | 2009-11-05 | Medivation Technologies, Inc. | Use of asenapine and related compounds for the treatment of neuronal or non-neuronal diseases or conditions |
| JP2012500800A (ja) * | 2008-08-21 | 2012-01-12 | リヒター ゲデオン ニルバーノシャン ミーケデーレスベニュタールシャシャーグ | 神経因性疼痛の治療法 |
| DK2421519T3 (en) | 2009-04-23 | 2017-02-06 | Univ Zuerich | NMDA RECEPTOR BLOCKERS FOR THE TREATMENT OF SEAL CELL ANAEMS |
| EP2466312B1 (en) | 2009-08-12 | 2019-10-16 | Human Metabolome Technologies, Inc. | Phosphoethanolamine as biomarker of depression |
| US8951968B2 (en) | 2009-10-05 | 2015-02-10 | Northwestern University | Methods of treating depression and other related diseases |
| PT2582366E (pt) | 2010-06-15 | 2016-01-26 | Gruenenthal Gmbh | Combinação terapêutica para o tratamento da dor |
| US9737531B2 (en) | 2012-07-12 | 2017-08-22 | Glytech, Llc | Composition and method for treatment of depression and psychosis in humans |
| CN112933073A (zh) | 2013-01-22 | 2021-06-11 | 维斯塔津治疗公司 | L-4-氯犬尿氨酸的剂型和治疗用途 |
| JP2016513718A (ja) | 2013-03-14 | 2016-05-16 | ヴィスタゲン セラピューティクス、インコーポレイテッド | キラルキヌレニン化合物及び中間体の合成 |
| CN105764522A (zh) | 2013-10-28 | 2016-07-13 | 诺雷克斯股份有限公司 | Nmda受体调节剂及其前药、盐和用途 |
| EA201792571A1 (ru) | 2015-05-22 | 2018-06-29 | Вистаджен Терапьютикс, Инк. | Терапевтическое применение l-4-хлорокинуренина |
-
2014
- 2014-01-22 CN CN202110387961.2A patent/CN112933073A/zh active Pending
- 2014-01-22 PT PT171700792T patent/PT3228313T/pt unknown
- 2014-01-22 CA CA2898619A patent/CA2898619C/en active Active
- 2014-01-22 ES ES17170079T patent/ES2751138T3/es active Active
- 2014-01-22 MX MX2015009277A patent/MX2015009277A/es active IP Right Grant
- 2014-01-22 ES ES14743570.5T patent/ES2635353T3/es active Active
- 2014-01-22 RS RS20191519A patent/RS59687B1/sr unknown
- 2014-01-22 KR KR1020237021428A patent/KR20230098711A/ko not_active Application Discontinuation
- 2014-01-22 CA CA3128321A patent/CA3128321C/en active Active
- 2014-01-22 DK DK17170079T patent/DK3228313T3/da active
- 2014-01-22 KR KR1020227044517A patent/KR20230003410A/ko not_active Application Discontinuation
- 2014-01-22 CN CN202110384159.8A patent/CN113116877A/zh active Pending
- 2014-01-22 EP EP17170079.2A patent/EP3228313B1/en active Active
- 2014-01-22 KR KR1020157022405A patent/KR102257284B1/ko active IP Right Grant
- 2014-01-22 IL IL291831A patent/IL291831A/en unknown
- 2014-01-22 AU AU2014209466A patent/AU2014209466B2/en active Active
- 2014-01-22 JP JP2015553921A patent/JP6436913B2/ja active Active
- 2014-01-22 WO PCT/US2014/012598 patent/WO2014116739A1/en active Application Filing
- 2014-01-22 EP EP19196366.9A patent/EP3598971B1/en active Active
- 2014-01-22 CA CA3216579A patent/CA3216579A1/en active Pending
- 2014-01-22 PL PL17170079T patent/PL3228313T3/pl unknown
- 2014-01-22 CN CN202110387953.8A patent/CN113209068A/zh active Pending
- 2014-01-22 PT PT147435705T patent/PT2948140T/pt unknown
- 2014-01-22 KR KR1020217039478A patent/KR20210149905A/ko not_active Application Discontinuation
- 2014-01-22 SI SI201431410T patent/SI3228313T1/sl unknown
- 2014-01-22 BR BR112015017535A patent/BR112015017535A2/pt not_active IP Right Cessation
- 2014-01-22 US US14/762,015 patent/US9993450B2/en active Active
- 2014-01-22 DK DK14743570.5T patent/DK2948140T3/en active
- 2014-01-22 EP EP14743570.5A patent/EP2948140B1/en active Active
- 2014-01-22 KR KR1020217015432A patent/KR102335919B1/ko active IP Right Grant
- 2014-01-22 CN CN201480010060.XA patent/CN105073108A/zh active Pending
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2015
- 2015-07-17 MX MX2020009966A patent/MX2020009966A/es unknown
- 2015-07-22 IL IL240090A patent/IL240090B/en active IP Right Grant
- 2015-08-03 ZA ZA2015/05569A patent/ZA201505569B/en unknown
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2016
- 2016-02-08 US US15/018,219 patent/US9993453B2/en active Active
- 2016-05-05 HK HK16105132.0A patent/HK1217170A1/zh unknown
- 2016-11-02 ZA ZA2016/07581A patent/ZA201607581B/en unknown
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2018
- 2018-05-14 US US15/978,855 patent/US10632091B2/en active Active
- 2018-06-08 US US16/003,816 patent/US10980758B2/en active Active
- 2018-06-08 US US16/003,804 patent/US20180369180A1/en not_active Abandoned
- 2018-06-08 US US16/003,793 patent/US10617663B2/en active Active
- 2018-09-13 JP JP2018171786A patent/JP6804497B2/ja active Active
- 2018-10-26 AU AU2018253600A patent/AU2018253600B2/en active Active
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2019
- 2019-11-27 CY CY20191101244T patent/CY1122403T1/el unknown
- 2019-12-04 HR HRP20192189TT patent/HRP20192189T1/hr unknown
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2020
- 2020-07-01 AU AU2020204420A patent/AU2020204420A1/en not_active Abandoned
- 2020-07-03 JP JP2020115273A patent/JP7021298B2/ja active Active
- 2020-07-16 IL IL276126A patent/IL276126B/en unknown
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2022
- 2022-02-03 JP JP2022015622A patent/JP2022070894A/ja active Pending
- 2022-06-21 US US17/845,105 patent/US20220409564A1/en active Pending
- 2022-08-22 AU AU2022221382A patent/AU2022221382A1/en active Pending
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