CN107927774A - A kind of health rhodiola capsule and preparation method thereof - Google Patents

A kind of health rhodiola capsule and preparation method thereof Download PDF

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Publication number
CN107927774A
CN107927774A CN201711002010.9A CN201711002010A CN107927774A CN 107927774 A CN107927774 A CN 107927774A CN 201711002010 A CN201711002010 A CN 201711002010A CN 107927774 A CN107927774 A CN 107927774A
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CN
China
Prior art keywords
rhodiola
capsule
sea
buckthorn
american ginseng
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Pending
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CN201711002010.9A
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Chinese (zh)
Inventor
田养东
唐晓勇
田永铭
侯全斌
田青
田亮
王明
潘晓
屈军
李向阳
祁守芳
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Qinghai Xinchiyuan Biotechnology Development Co Ltd
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Qinghai Xinchiyuan Biotechnology Development Co Ltd
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Priority to CN201711002010.9A priority Critical patent/CN107927774A/en
Publication of CN107927774A publication Critical patent/CN107927774A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105Plant extracts, their artificial duplicates or their derivatives
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

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  • Life Sciences & Earth Sciences (AREA)
  • Mycology (AREA)
  • Health & Medical Sciences (AREA)
  • Nutrition Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Botany (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)

Abstract

The invention discloses a kind of health rhodiola capsule and preparation method thereof.A kind of health rhodiola capsule, containing rhodiola root, American Ginseng and sea-buckthorn, its preparation method dries for rhodiola root, sea-buckthorn and American Ginseng crude drug are cleaned up, American Ginseng dry, pulverize and cross 100 mesh sieves;By rhodiola root and sea-buckthorn, extracted with 70% alcohol reflux and merge extracting solution, filtering, is dried under reduced pressure, then crushes, and crosses 80 mesh sieves;Gained powder is uniformly mixed, softwood is made with the ethanol that mass fraction is 80%, 20 mesh sieves are pelletized, 55 60 DEG C of dryings, and 16 mesh sieve whole grains load No. 0 capsule and capsule is made, and pack up to Rhodiola rosea capsules of the present invention.

Description

A kind of health rhodiola capsule and preparation method thereof
Technical field
The invention belongs to health products production field, more particularly, to a kind of Rhodiola rosea capsules and preparation method thereof.
Background technology
Rhodiola root is most one of precious medicinal plant of mystery flavour in Tibetan medicine, is respectfully called " sulu agate by Tibetan people It is precious ", it means " god's medicine ", " nostrum ".Rhodiola root is mainly grown on the severe cold of more than 3000 meters of Qinghai-Tibet height above sea level, anoxic, strong Sunshine, free of contamination area, unique rugged environment create its indomitable vitality and mirable drug effect.Modern medicine Show, rhodiola root has anti anoxia, cold resistance, antifatigue, radioresistance and delays body aging, prevents some infirmitiess of age etc. Effect.Rhodiola root contains more than 100 kinds of chemical composition, is a kind of health medicine of natural formula.
In recent years, Qinghai-Tibetan Tourism is persistently overheating, and many long-term people for living in plains region have perhaps after reaching plateau Discomfort more, Rhodiola species medicine materical crude slice and patent medicine become the medicine of preferred prevention and treatment altitude sickness.However, due to wild red scape The unreasonable exploitation of its resource utilizes, and causes the destruction Of resources serious, and resource utilization is not high, and added value of product is low, fake and forged Seriously, lack effective with raising anoxia endurance health rhodiola capsule product.
The content of the invention
In order to solve the problems in the existing technology, the present invention provides a kind of health rhodiola capsule and its preparation side Method, the product safety is nontoxic can to effectively improve human body anoxia tolerance.
The present invention is achieved by the following technical solutions.
A kind of health rhodiola capsule, it is characterised in that including following component, rhodiola root, American Ginseng and sea-buckthorn;
Further, the Rhodiola rosea capsules, including following component by weight ratio:200-1000 parts of rhodiola root, west 200-1000 parts of 500-900 parts of American ginseng and sea-buckthorn.
Further, the Rhodiola rosea capsules, including following component by weight ratio:700 parts of rhodiola root, American Ginseng 900 parts and 500 parts of sea-buckthorn.
A kind of preparation method of health rhodiola capsule, it is characterised in that comprise the following steps:
D1:Rhodiola root, sea-buckthorn and American Ginseng crude drug are cleaned up, dried, it is spare after the assay was approved;
D2:By formula weigh the dry 0.5-2 of 60 DEG C of American Ginseng through D1 step process it is small when, crush simultaneously mistake 100 mesh sieves, powder End is spare;
D3:Rhodiola root and sea-buckthorn through D1 step process are weighed by formula, adds 70% alcohol reflux of 5-10 times of volume Extraction 2-4 times, when extraction 1-3 is small every time, filtering, merges extracting solution, dense through 60 DEG C of decompressions with 150-300 mesh screens, filtrate The thick paste that relative density is 1.3-1.35 is reduced to, thick paste is dried under reduced pressure at 70 DEG C, is then crushed, crosses 80 mesh sieves, powder is spare;
D4:Powder obtained by D2 and D3 is uniformly mixed, softwood, 20 mesh sieve series are made with the ethanol that mass fraction is 80% Grain, 55-60 DEG C of drying, 16 mesh sieve whole grains are spare;
D5:Particle obtained by D4 steps is loaded into No. 0 capsule capsule is made, packed up to rhodiola root glue of the present invention Capsule.
Further, when drying time is 1 small in the step D2;
Further, in the step 3,70% alcohol reflux for adding 7 times of volumes extracts 3 times, when extraction 2 is small every time;
Further, in the step 3, extracting solution is merged, with 200 mesh screens.
The present invention has the advantage that compared with prior art:
1st, simple production process of the present invention, is high-quality, high added value, pure natural, pollution-free health-care beverage product, its is heavy It is medicinal and edible plant to want raw material rhodiola root, itself has unique health-care efficacy, and from free of contamination Qinghai-Tibet Platean ground Area, meets pursuit of the current people to the demand such as green, natural, pollution-free, high-efficient health-care, has good market prospects, only Since 2017, accumulated sales revenue is up to 20,000,000 yuan;
2nd, health rhodiola capsule of the invention experiment shows without any side effects, while has raising hypoxic tolerance Power, alleviate the multiple efficacies such as physical fatigue.
Attached drawing
Fig. 1 is health rhodiola capsule manufacture flow chart of the present invention
Embodiment
Below in conjunction with the attached drawing in the embodiment of the present invention, the technical solution in the embodiment of the present invention is carried out clear, complete Site preparation describes, it is clear that described embodiment is only part of the embodiment of the present invention, instead of all the embodiments.It is based on Embodiment in the present invention, those of ordinary skill in the art are obtained every other without making creative work Embodiment, belongs to the scope of protection of the invention.
Embodiment 1
A kind of health rhodiola capsule, it is characterised in that including following component by weight ratio:700 parts of rhodiola root, 500 parts of 900 parts of American Ginseng and sea-buckthorn.
A kind of preparation method of health rhodiola capsule, it is characterised in that comprise the following steps:
D1:Rhodiola root, sea-buckthorn and American Ginseng crude drug are cleaned up, dried, it is spare after the assay was approved;
D2:By formula weigh 60 DEG C of drying 1 of American Ginseng through D1 step process it is small when, crush simultaneously 100 mesh sieves of mistake, powder is standby With;
D3:Rhodiola root and sea-buckthorn through D1 step process are weighed by formula, adds the 70% alcohol reflux extraction of 7 times of volumes 3 times, when extraction 2 is small every time, filtering, merges extracting solution, with 200 mesh screens, filtrate is concentrated under reduced pressure into relative density through 60 DEG C For 1.3 thick paste, thick paste is dried under reduced pressure at 70 DEG C, is then crushed, cross 80 mesh sieves, powder is spare;
D4:Powder obtained by D2 and D3 is uniformly mixed, softwood, 20 mesh sieve series are made with the ethanol that mass fraction is 80% Grain, 55-60 DEG C of drying, 16 mesh sieve whole grains are spare;
D5:Particle obtained by D4 steps is loaded into No. 0 capsule capsule is made, packed up to rhodiola root glue of the present invention Capsule.
Embodiment 2
A kind of health rhodiola capsule, it is characterised in that including following component by weight ratio:Rhodiola root 1000 1000 parts of part, 900 parts of American Ginseng and sea-buckthorn.
A kind of preparation method of health rhodiola capsule, it is characterised in that comprise the following steps:
D1:Rhodiola root, sea-buckthorn and American Ginseng crude drug are cleaned up, dried, it is spare after the assay was approved;
D2:By formula weigh 60 DEG C of drying 2 of American Ginseng through D1 step process it is small when, crush simultaneously 100 mesh sieves of mistake, powder is standby With;
D3:Rhodiola root and sea-buckthorn through D1 step process are weighed by formula, adds 70% alcohol reflux of 5-10 times of volume Extraction 4 times, when extraction 3 is small every time, filtering, merges extracting solution, and with 300 mesh screens, filtrate is concentrated under reduced pressure into opposite through 60 DEG C Density is 1.33 thick paste, and thick paste is dried under reduced pressure at 70 DEG C, is then crushed, and crosses 80 mesh sieves, and powder is spare;
D4:Powder obtained by D2 and D3 is uniformly mixed, softwood, 20 mesh sieve series are made with the ethanol that mass fraction is 80% Grain, 58 DEG C of dryings, 16 mesh sieve whole grains are spare;
D5:Particle obtained by D4 steps is loaded into No. 0 capsule capsule is made, packed up to rhodiola root glue of the present invention Capsule.
Embodiment 3
A kind of health rhodiola capsule, it is characterised in that including following component by weight ratio:200 parts of rhodiola root, 200 parts of 500 parts of American Ginseng and sea-buckthorn.
A kind of preparation method of health rhodiola capsule, it is characterised in that comprise the following steps:
D1:Rhodiola root, sea-buckthorn and American Ginseng crude drug are cleaned up, dried, it is spare after the assay was approved;
D2:By formula weigh 60 DEG C of drying 0.5 of American Ginseng through D1 step process it is small when, crush simultaneously mistake 100 mesh sieves, powder It is spare;
D3:Rhodiola root and sea-buckthorn through D1 step process are weighed by formula, 70% alcohol reflux for adding 10 times of volumes carries Take 3 times, when extraction 2 is small every time, filtering, merges extracting solution, with 150 mesh screens, filtrate is concentrated under reduced pressure into relatively close through 60 DEG C The thick paste for 1.31 is spent, thick paste is dried under reduced pressure at 70 DEG C, is then crushed, crosses 80 mesh sieves, powder is spare;
D4:Powder obtained by D2 and D3 is uniformly mixed, softwood, 20 mesh sieve series are made with the ethanol that mass fraction is 80% Grain, 57 DEG C of dryings, 16 mesh sieve whole grains are spare;
D5:Particle obtained by D4 steps is loaded into No. 0 capsule capsule is made, packed up to rhodiola root glue of the present invention Capsule.
Embodiment 4
A kind of health rhodiola capsule, it is characterised in that including following component by weight ratio:300 parts of rhodiola root, 300 parts of 900 parts of American Ginseng and sea-buckthorn.
A kind of preparation method of health rhodiola capsule, it is characterised in that comprise the following steps:
D1:Rhodiola root, sea-buckthorn and American Ginseng crude drug are cleaned up, dried, it is spare after the assay was approved;
D2:By formula weigh 60 DEG C of drying 1.5 of American Ginseng through D1 step process it is small when, crush simultaneously mistake 100 mesh sieves, powder It is spare;
D3:Rhodiola root and sea-buckthorn through D1 step process are weighed by formula, adds the 70% alcohol reflux extraction of 7 times of volumes 2 times, when extraction 2 is small every time, filtering, merges extracting solution, with 200 mesh screens, filtrate is concentrated under reduced pressure into relative density through 60 DEG C For 1.3 thick paste, thick paste is dried under reduced pressure at 70 DEG C, is then crushed, cross 80 mesh sieves, powder is spare;
D4:Powder obtained by D2 and D3 is uniformly mixed, softwood, 20 mesh sieve series are made with the ethanol that mass fraction is 80% Grain, 55 DEG C of dryings, 16 mesh sieve whole grains are spare;
D5:Particle obtained by D4 steps is loaded into No. 0 capsule capsule is made, packed up to rhodiola root glue of the present invention Capsule.
Embodiment 5
A kind of health rhodiola capsule, it is characterised in that including following component by weight ratio:900 parts of rhodiola root, 900 parts of 900 parts of American Ginseng and sea-buckthorn.
A kind of preparation method of health rhodiola capsule, it is characterised in that comprise the following steps:
D1:Rhodiola root, sea-buckthorn and American Ginseng crude drug are cleaned up, dried, it is spare after the assay was approved;
D2:By formula weigh 60 DEG C of drying 1.5 of American Ginseng through D1 step process it is small when, crush simultaneously mistake 100 mesh sieves, powder It is spare;
D3:Rhodiola root and sea-buckthorn through D1 step process are weighed by formula, adds the 70% alcohol reflux extraction of 7 times of volumes 2 times, when extraction 2 is small every time, filtering, merges extracting solution, with 300 mesh screens, filtrate is concentrated under reduced pressure into relative density through 60 DEG C For 1.35 thick paste, thick paste is dried under reduced pressure at 70 DEG C, is then crushed, cross 80 mesh sieves, powder is spare;
D4:Powder obtained by D2 and D3 is uniformly mixed, softwood, 20 mesh sieve series are made with the ethanol that mass fraction is 80% Grain, 60 DEG C of dryings, 16 mesh sieve whole grains are spare;
D5:Particle obtained by D4 steps is loaded into No. 0 capsule capsule is made, packed up to rhodiola root glue of the present invention Capsule.
Experimental example
1st, health rhodiola capsule Toxicological evaluation of the present invention test result indicates that:Health rhodiola capsule pair Large and small mouse acute oral toxicity test result MTD values are equal>15000mg/kg.BW, is classified by acute toxicity, belongs to non-toxic.
Three genetic toxicity tests (Ames experiments, mouse bone marrow polychromatic erythrocytes nuclear test and mouse sperm deformities Experiment) result has no that lattice draw Dandong board Rhodiola rosea capsules mutagenesis.30 days feeding trials, it is seen that animal growth is just Often, continued weight increases, and figure is active, and hair is smooth submissive, and stool, urine no abnormality seen changes.Have no that animal goes out during experiment Existing poisoning symptom and death.The weight weekly of three dosage group male and female rats, weekly food-intake, weekly food utilization and total food Thing utilization rate and dirty body ratio compared with the control group, there was no significant difference (P>0.05);The hematology of three dosage group animals Index, latter stage blood biochemistry index are compared with control group, (the P in addition to the leucocyte of female mice low dose group is substantially less than control group< 0.05), remaining indices there are no significant difference (P>0.05).Above institute's measured value is in this room range of normal value.Tissue disease Inspection result of science, in addition to the spontaneous lesion of animal, has no that tested material high dose group causes animal poisoning damage to change.
2nd, anoxia tolerant function zoopery is improved to show:Submitted sample lattice draw Dandong board Rhodiola rosea capsules to improve anoxic Tolerance function results of animal shows:Lattice draw board Rhodiola rosea capsules continuous 30 days oral gavages in Dandong to give male mice Afterwards, it is seen that growth of animal is good, and continued weight increases.
Compared with the control group, middle and high dosage group prolonged survival period has the Hypoxia under normal pressure of three dosage group mouse Significant difference (P<0.01、P<0.05), normal pressure anoxia tolerance test result is the positive.
The sodium nitrite of three dosage group mouse is poisoned the time-to-live compared with the control group, the middle and high dosage group time-to-live Performance has significant difference (P<0.05、P<0.05), nitrous acid poisoning survival experimental result is the positive.
Ischemia Injury in Brain anoxic experimental result is feminine gender.
Foundation《Health food is examined and assessment technique specification》(version in 2003) can be determined that, lattice draw Dandong board rhodiola root glue Capsule, which has animal, improves anoxia tolerant function.
Although an embodiment of the present invention has been shown and described, for the ordinary skill in the art, can be with Understanding without departing from the principles and spirit of the present invention can carry out these embodiments a variety of changes, modification, replace And modification, the scope of the present invention is defined by the appended.

Claims (4)

1. a kind of health rhodiola capsule, it is characterised in that including following component, rhodiola root, American Ginseng and sea-buckthorn.
2. a kind of health rhodiola capsule, it is characterised in that including following component by weight ratio:Rhodiola root 200-1000 200-1000 parts of part, 500-900 parts of American Ginseng and sea-buckthorn.
3. a kind of health rhodiola capsule, it is characterised in that including following component by weight ratio:700 parts of rhodiola root, west 500 parts of 900 parts of American ginseng and sea-buckthorn.
4. according to a kind of preparation method of any health rhodiola capsules of claim 1-3, it is characterised in that including with Lower step:
D1:Rhodiola root, sea-buckthorn and American Ginseng crude drug are cleaned up, dried, it is spare after the assay was approved;
D2:By formula weigh the dry 0.5-2 of 60 DEG C of American Ginseng through D1 step process it is small when, crush simultaneously 100 mesh sieves of mistake, powder is standby With;
D3:Rhodiola root and sea-buckthorn through D1 step process are weighed by formula, adds the 70% alcohol reflux extraction of 5-10 times of volume 2-4 times, when extraction 1-3 is small every time, filtering, merges extracting solution, with 150-300 mesh screens, filtrate is concentrated under reduced pressure into through 60 DEG C Relative density is the thick paste of 1.3-1.35, and thick paste is dried under reduced pressure at 70 DEG C, is then crushed, and crosses 80 mesh sieves, and powder is spare;
D4:Powder obtained by D2 and D3 is uniformly mixed, softwood, the granulation of 20 mesh sieves, 55- is made with the ethanol that mass fraction is 80% 60 DEG C of dryings, 16 mesh sieve whole grains are spare;
D5:Particle obtained by D4 steps is loaded into No. 0 capsule capsule is made, packed up to Rhodiola rosea capsules of the present invention.
CN201711002010.9A 2017-10-24 2017-10-24 A kind of health rhodiola capsule and preparation method thereof Pending CN107927774A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108641870A (en) * 2018-05-30 2018-10-12 金花企业(集团)股份有限公司西安金花制药厂 A kind of health liquor and preparation method thereof with strengthen immunity and anti-fatigue effect

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1686396A (en) * 2005-04-11 2005-10-26 王奉友 Health care product having anoxia tolerance function
CN101129441A (en) * 2007-09-20 2008-02-27 尹治华 Rhodiola rosea capsule and its preparing method
CN101595988A (en) * 2008-12-11 2009-12-09 广州中一药业有限公司 A kind of tired health food preparation and preparation method thereof of alleviating
CN102960715A (en) * 2012-09-07 2013-03-13 无锡市天赐康生物科技有限公司 Immunity-enhancing and hypoxia tolerant health food and preparation method thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1686396A (en) * 2005-04-11 2005-10-26 王奉友 Health care product having anoxia tolerance function
CN101129441A (en) * 2007-09-20 2008-02-27 尹治华 Rhodiola rosea capsule and its preparing method
CN101595988A (en) * 2008-12-11 2009-12-09 广州中一药业有限公司 A kind of tired health food preparation and preparation method thereof of alleviating
CN102960715A (en) * 2012-09-07 2013-03-13 无锡市天赐康生物科技有限公司 Immunity-enhancing and hypoxia tolerant health food and preparation method thereof

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Title
编辑:E路: "格拉丹东牌红景天西洋参沙棘胶囊,http://www.kuailedo.com/bjpcx/041515266.html", 《快乐多资讯网》 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108641870A (en) * 2018-05-30 2018-10-12 金花企业(集团)股份有限公司西安金花制药厂 A kind of health liquor and preparation method thereof with strengthen immunity and anti-fatigue effect

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Application publication date: 20180420