CN107918029B - Automatic sample introduction device - Google Patents

Automatic sample introduction device Download PDF

Info

Publication number
CN107918029B
CN107918029B CN201610884853.5A CN201610884853A CN107918029B CN 107918029 B CN107918029 B CN 107918029B CN 201610884853 A CN201610884853 A CN 201610884853A CN 107918029 B CN107918029 B CN 107918029B
Authority
CN
China
Prior art keywords
test tube
rod
rotating shaft
swing
supporting rod
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
CN201610884853.5A
Other languages
Chinese (zh)
Other versions
CN107918029A (en
Inventor
卢江涛
邵汉荣
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sonoscape Medical Corp
Original Assignee
Sonoscape Medical Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sonoscape Medical Corp filed Critical Sonoscape Medical Corp
Priority to CN201610884853.5A priority Critical patent/CN107918029B/en
Priority to PCT/CN2017/093474 priority patent/WO2018068549A1/en
Publication of CN107918029A publication Critical patent/CN107918029A/en
Application granted granted Critical
Publication of CN107918029B publication Critical patent/CN107918029B/en
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Images

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N2035/1027General features of the devices
    • G01N2035/1048General features of the devices using the transfer device for another function
    • G01N2035/1058General features of the devices using the transfer device for another function for mixing

Landscapes

  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Sampling And Sample Adjustment (AREA)

Abstract

The invention relates to the field of medical and health instruments, and discloses an automatic sample feeding device which comprises a sample separating device, a blending device and a discharging device, wherein the blending device is arranged below the sample separating device, the discharging device is arranged below the blending device, the sample separating device is used for separating an individual test tube row from a plurality of test tube rows for storing samples, the individual test tube row is mixed after falling into the blending device, and the test tube row falls into the discharging device at the blending device for discharging. The device can automatically complete the steps of separation, uniform mixing, puncture, unloading and the like of the test tube row along the vertical direction, has compact structure, small occupied space and shorter movement stroke of the test tube row, and is beneficial to shortening time and improving efficiency; the sample separation device is arranged, a plurality of test tube banks can be added at one time, and the workload of feeding is reduced.

Description

Automatic sample introduction device
Technical Field
The invention relates to the field of medical and health instruments, in particular to an automatic sample feeding device.
Background
With the progress of the technology, the application of automatic equipment in the fields of biochemical research, medical detection and the like is more and more extensive, taking the analysis of blood cells as an example, the steps of feeding, uniformly mixing, puncturing, blanking and the like need to be involved in the analysis of samples, the existing automatic equipment generally drives the samples to horizontally move among various stations through a material moving device so as to complete the steps, however, the mode needs to occupy larger space and is inconvenient for practical use, and meanwhile, the samples need to pass through longer transfer stroke, and the working efficiency is not high.
Disclosure of Invention
In order to overcome the defects of the prior art, the invention provides an automatic sample feeding device.
The technical scheme adopted by the invention for solving the technical problems is as follows:
the utility model provides an autoinjection device, includes sample separator, locates the mixing device of sample separator below to and locate the discharge apparatus of mixing device below, wherein, sample separator is used for separating solitary test tube row from a plurality of test tube rows of depositing the sample, and this solitary test tube row carries out the mixing after falling into mixing device, and the test tube row falls into discharge apparatus department in mixing device department and carries out the operation of unloading.
As a further improvement of the above solution, the sample separation device comprises a linkage mechanism and a support device disposed below the linkage mechanism, the support device comprises an openable support plate, the support plate is used for receiving the test tube rows stacked in the vertical direction when closed and allowing the test tube rows to freely fall when opened; the connecting rod mechanism comprises a first supporting rod and a second supporting rod which are oppositely arranged, the first supporting rod and the second supporting rod can be relatively close to or separated from each other, the first supporting rod and the second supporting rod can support the test tube rows on the penultimate layer and above when the first supporting rod and the second supporting rod are relatively close to each other, and the test tube rows can be allowed to freely fall when the first supporting rod and the second supporting rod are relatively far away from each other.
As a further improvement mode of the scheme, the link mechanism comprises a first swing rod, a second swing rod, a first rotating shaft, a second rotating shaft and a slide rod, wherein the first rotating shaft and the second rotating shaft are parallel to each other, one end of the first swing rod and one end of the second swing rod are respectively connected with the first rotating shaft and the second rotating shaft, the other ends of the first swing rod and the second swing rod are respectively connected with two ends of the slide rod in a rotating manner, a first support rod and a second support rod are respectively connected to the first rotating shaft and the second rotating shaft through the swing rods, the first swing rod and the second swing rod can swing in the same direction through the slide rod to further respectively drive the first support rod and the second support rod to synchronously swing, the first support rod is positioned below the first rotating shaft, the second support rod is positioned above the second rotating shaft, the first support rod and the second support rod are positioned in the same horizontal plane, when the first swing rod and the second swing rod swing in the first direction, the first support rod and the second support rod are relatively close, the first support rod and the second support rod are relatively far away.
As a further improvement mode of the scheme, the supporting device comprises a third rotating shaft, a fourth rotating shaft, a third oscillating bar, a fourth oscillating bar, a sliding block and a linear motor, the third rotating shaft and the fourth rotating shaft are parallel to each other and are fixedly connected with the supporting plate respectively, one end of the third oscillating bar and one end of the fourth oscillating bar are fixedly connected with the third rotating shaft and the fourth rotating shaft respectively, the other end of the third oscillating bar and the other end of the fourth oscillating bar are rotatably connected with the sliding block and can slide along the length direction of the sliding block relative to the sliding block, the sliding block can reciprocate in the vertical direction under the driving of the linear motor, and then the supporting plate is driven to rotate in a reciprocating mode.
As the further improvement mode of above-mentioned scheme, the mixing device includes support and mixing groove, is equipped with the opening that supplies the test tube row business turn over on the mixing groove, and the mixing groove is connected with the support to can wind an axle center and relative support rotation, and this mixing groove can be fixed at the opening state up, the opening state down and erect at least.
As a further improvement mode of the scheme, the device also comprises a displacement device and a puncture device, wherein the blending device reciprocates through the displacement device, and the puncture device is arranged on a moving path of the displacement device.
As a further improvement mode of the scheme, the blending groove is fixed in a vertical state when moving, and a plurality of puncture holes are arranged at the top of the blending groove when the blending groove is in the vertical state, and the puncture holes are respectively aligned with the test tubes in the test tube row.
The blending groove is fixed in a state that the opening is downward, the sliding rod slides to a second position from a first position, the clamping hooks synchronously move in the opposite direction, and the distance between the clamping hooks is not less than the width or the length of the opening; when the blending groove rotates, the sliding rod slides to the first position from the second position, the clamping hooks synchronously move in opposite directions, and the distance between the clamping hooks is smaller than the width or the length of the opening.
The improved structure of the technical scheme comprises a first spring and a driving rod which are arranged corresponding to a clamping hook, wherein one end of the driving rod is abutted against a sliding rod, the other end of the driving rod is connected with the corresponding clamping hook, and the first spring is sleeved on the driving rod and is compressed when the clamping hook moves reversely relative to the opposite clamping hook; grooves are symmetrically arranged at the positions, abutted against the driving rod, of the two sides of the sliding rod, wherein when the sliding rod is located at the first position, the driving rod slides into the grooves; when the slide bar is at the second position, the driving rod slides out of the groove.
As the further improved mode of above-mentioned scheme, discharge apparatus includes material returned fork and returning face plate, and wherein the material returned fork is used for driving the test tube row motion, and the returning face plate is used for driving the test tube row upset, and wherein the drive stroke of material returned fork is including driving the first stroke that the test tube row moved to the returning face plate to and the second stroke that drives the test tube row after the upset and move to the position of unloading from the returning face plate.
As a further improvement mode of the scheme, the material returning fork comprises a horizontal first bearing plate and a vertical first limiting plate arranged at the head end of the first bearing plate, and a first accommodating space for accommodating the test tube bank is formed between the first limiting plate and the first bearing plate; the turnover plate comprises a second bearing plate and a vertical third bearing plate arranged at the tail end of the second bearing plate, a second accommodating space for accommodating the test tube bank is formed between the second bearing plate and the third bearing plate, and the rotating shaft is arranged at the joint of the second bearing plate and the third bearing plate; the second bearing plate and the third bearing plate are arranged above the first bearing plate, the second bearing plate is provided with a notch which runs through the bottom of the second bearing plate and the third bearing plate, and the first bearing plate and the first limiting plate can cross the second bearing plate and the third bearing plate through the notch after the second bearing plate and the third bearing plate are turned over.
The invention has the beneficial effects that:
the steps of separation, uniform mixing, puncture, unloading and the like of the test tube rows can be automatically completed along the vertical direction, the device has a compact structure, the occupied space is small, and the volume of the whole machine is reduced; the movement stroke of the test tube bank is shorter, so that the time is shortened, and the efficiency is improved; the sample separation device is arranged, a plurality of test tube banks can be added at one time, and the workload of feeding is reduced.
The automatic sample feeding device provided by the invention reduces the use of an external power source as much as possible, saves energy and reduces the influence caused by the heat of the motor.
Drawings
The invention is further illustrated with reference to the following figures and examples.
FIG. 1 is a schematic perspective view of one embodiment of the present invention;
FIG. 2 is an exploded schematic view of one embodiment of the present invention;
FIG. 3 is a schematic perspective view of a sample separation device according to the present invention in an unsupported state;
FIG. 4 is a side view of a sample separation device of the present invention in an unsupported state;
FIG. 5 is a perspective view of the display support device of the present invention;
FIG. 6 is a side view of a sample separation device of the present invention in a supported state;
FIG. 7 is a schematic perspective view of one embodiment of a blending apparatus of the present invention;
FIG. 8 is a side view of the mixing apparatus of the present invention with the mixing tank in an upright position;
FIG. 9 is a schematic view of the test tube bank locking device of the present invention in a clamped state;
FIG. 10 is a schematic view of the tube bank locking device of the present invention in an open position;
FIG. 11 is a schematic perspective view of one embodiment of a discharge apparatus of the present invention;
FIG. 12 is a schematic view of the discharge apparatus of the present invention at an initial stage;
FIG. 13 is a schematic view of the discharge device with the discharge fork at the end of the first stroke;
FIG. 14 is a schematic view of the discharge device after the roll-over plate has been turned over;
fig. 15 is a schematic view of the discharge device with the discharge fork at the end of the second stroke.
Detailed Description
The conception, the specific structure and the technical effects of the present invention will be clearly and completely described in conjunction with the embodiments and the accompanying drawings to fully understand the objects, the schemes and the effects of the present invention. It should be noted that the embodiments and features of the embodiments in the present application may be combined with each other without conflict.
It should be noted that, unless otherwise specified, when a feature is referred to as being "fixed" or "connected" to another feature, it may be directly fixed or connected to the other feature or indirectly fixed or connected to the other feature. Further, the description of the upper, lower, left, right, etc. used in the present invention is only with respect to the positional relationship of the respective components of the present invention with respect to each other in the drawings.
Furthermore, unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art. The terminology used in the description herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. As used herein, the term "and/or" includes any combination of one or more of the associated listed items.
Referring to fig. 1 and 2, which respectively show an overall schematic view and an exploded schematic view of an embodiment of the present invention, as shown in the figures, the present invention includes a sample separation device 100, a blending device 200 disposed below the sample separation device 100, and a discharging device 300 disposed below the blending device 200, wherein the sample separation device 100 is configured to separate an individual test tube row from a plurality of test tube rows storing samples, the individual test tube row is dropped into the blending device 200 and then is subjected to blending operation, the test tube row is finally subjected to discharging operation at the place where the blending device is dropped into the discharging device 300, the stored test tube row is vertically disposed, the devices are also vertically disposed, the test tube rows are sequentially subjected to steps of separating, blending, and subsequent discharging in a gradual dropping process, which helps to reduce the overall volume of the device, reduce the space occupation, and at the same time, the test tube rows freely drop under the action of gravity, need not to set up extra drive arrangement, the structure is simpler, and the stroke of test tube row is also shorter, helps promoting production efficiency.
Sample separation device 100
The sample separation device comprises a connecting rod mechanism and a supporting device, wherein the supporting device is used for bearing a plurality of test tube rows stacked along the vertical direction, and the connecting rod mechanism can support the test tube rows on the penultimate layer and above so as to enable the test tube row on the bottommost layer to move freely. Preferably, the supporting device in this embodiment adopts a door-type structure capable of opening and closing, and when the door-type structure is opened, the unsupported test tube row can fall freely, so as to achieve the purpose of layering, and of course, the test tube row can also be separated from the test tube row group from the side direction.
Referring to fig. 3 and 4, which respectively show a schematic perspective view and a side view of a sample separation device in an unsupported state, and show a test tube row, the two sides of the bottom of the test tube row to which the present invention is applied should be provided with a clamping groove (specifically referring to fig. 1 and 3, the clamping groove is arranged along two short edges of the bottom of the test tube row), and the clamping groove can form an inward concave space between adjacent test tube rows for supporting the test tube row after a support rod extends into the test tube row, as an alternative form of the above scheme, the clamping groove can be arranged on the side wall of the test tube row, and the clamping groove can be replaced by a structure such as a jack; in addition, also can not set up draw-in groove or jack, but set up a plurality of protruding structures in the bottom of test tube row to form the clearance between adjacent test tube row when making test tube row range upon range of placing, the bracing piece stretches into and equally can realize supporting the purpose of test tube row in the clearance.
Specifically, the link mechanism includes a first swing link 101, a second swing link 102, a first rotating shaft 103, a second rotating shaft 104, a first supporting rod 105, a second supporting rod 106, a fifth swing link 107, a sixth swing link 108, and a sliding rod 109.
The first rotating shaft and the second rotating shaft are parallel to each other, the first swing rod and the second swing rod are vertical to the first rotating shaft and the second rotating shaft respectively, and the sliding rod 109 is vertical to the first swing rod and the second swing rod respectively. The top end of the first swing rod 101 is fixedly connected with the first rotating shaft 103, the tail end of the first swing rod is rotatably connected with the left end of the sliding rod 109, the top end of the second swing rod 102 is fixedly connected with the second rotating shaft 104, and the tail end of the second swing rod is rotatably connected with the right end of the sliding rod 109, so that the first swing rod and the second swing rod can swing in the same direction through the sliding rod 109.
One end of a fifth swing link 107 is fixedly connected with the first rotating shaft 103, the other end of the fifth swing link is rotatably connected with a first supporting rod 105, and the first supporting rod 105 can synchronously move along with the fifth swing link 107; one end of a sixth oscillating bar 108 is fixedly connected with the second rotating shaft 104, the other end of the sixth oscillating bar is rotatably connected with a second supporting rod 106, the second supporting rod 106 can synchronously move along with the sixth oscillating bar 108, the first supporting rod and the second supporting rod are horizontally and oppositely arranged, and preferably, the fifth oscillating bar and the sixth oscillating bar are respectively parallel to the first oscillating bar and the second oscillating bar.
Different from the above embodiments, the present invention further provides another way of fixing the first and second support rods, that is, the first and second support rods are respectively mounted on the first and second swing rods, which can also achieve the purpose of synchronous movement of the support rods along with the swing rods, and at this time, the swing rods may be either fixed to the rotating shaft and then synchronously rotated, or rotated relative to the rotating shaft.
First bracing piece 105 is located one side of first pivot 103, second bracing piece 106 is located second pivot 104 and is different from the opposite side of first bracing piece 105, concretely, first bracing piece 105 is located the below of first pivot 103 in this embodiment, second bracing piece 106 is located the top of second pivot 104, when guaranteeing first, second pendulum rod syntropy swing promptly, the direction of motion between first, the second bracing piece is opposite, thereby realize first, the relative being close to and keeping away from of second bracing piece, and then realize that the support and the support of test tube row remove, first in the figure, the second pendulum rod is in the initial condition before the swing, the interval between first, the second bracing piece is the biggest, test tube row can be free pass through between the bracing piece.
More preferably, the first rotating shaft 103 is higher than the second rotating shaft 104, so that the first and second support rods are located in the same horizontal plane.
As a preferable connection mode between the first swing link, the second swing link and the slide rod, one end of the first swing link and one end of the second swing link, which are connected with the slide rod 109, are provided with sliding grooves, two ends of the slide rod 109 are provided with vertical pins (not shown), which are respectively inserted into the sliding grooves of the first swing link and the second swing link, so that the first swing link and the second swing link can rotate relative to the slide rod 109 and can slide along the grooves, and further the slide rod can only slide along the horizontal direction, of course, the slide rod 109 and the first swing link and the second swing link can only have a rotation relation, and at this time, the slide rod 109 can also move in the vertical direction during the swing process of the first swing link and the second swing.
In addition, the sliding rod 109 is fixed by a support 110, a through hole is arranged on the support 110, the sliding rod 109 is inserted into the through hole and can slide relative to the through hole, a return spring 111 is further sleeved on the sliding rod 109, the support 110 at the right end of the return spring 111 abuts against, and the left end of the return spring abuts against a stop block on the sliding rod 109, so that the initial state of the first swing rod and the initial state of the second swing rod are kept in a state before supporting, and the first swing rod and the second swing rod are provided with reset power after swinging.
The driving part of the link mechanism may be any one of the first rotating shaft, the second rotating shaft, the swing rod and the sliding rod, in this embodiment, the second rotating shaft is used for driving, specifically, a driving plate 112 is installed on the second rotating shaft, and the driving plate 112 can be driven by a blending groove described below to drive the link mechanism to move.
Referring to fig. 5, the supporting device includes a first supporting plate 113 and a second supporting plate 114, which are symmetrically disposed, a third rotating shaft 115, a fourth rotating shaft 116, a third swing link 117, a fourth swing link 118, a slider 119, and a linear motor 120, where the third and fourth rotating shafts are parallel to each other and are respectively fixed to the first and second supporting plates, so that the first and second supporting plates can rotate in opposite directions through the third and fourth rotating shafts, respectively.
The third and fourth swing links are located on both sides of the slider 119, one end of each swing link is fixedly connected to the third and fourth rotating shafts, respectively, and is perpendicular to the corresponding rotating shaft, the other end of each swing link is rotatably connected to the slider 119 and can slide along the length direction of the slider 119 relative to the slider, specifically, a sliding slot along the length direction of the swing link is formed in each swing link, and the slider 119 is connected to the sliding slot through a pin.
The slide block 119 can reciprocate in the vertical direction under the driving of the linear motor 120, and then the first support plate and the second support plate are driven to rotate in a reciprocating manner through the third oscillating bar and the fourth oscillating bar and the third rotating shaft and the fourth rotating shaft, so that the opening and closing of the support device can be realized.
Referring to fig. 6, which shows a side view of the sample separation apparatus in a support state, the first and second swing links are moved in a first direction (towards the right) to an extreme position, the first and second support bars are spaced closest to each other and less than the length of the tube array, and the return spring 111 is in a compressed state.
The specific working flow of the sample separation device is as follows with reference to the attached drawings and the description:
first, the second pendulum rod is located the leftmost side of swing route during initial condition, and the interval between first, the second bracing piece is greater than the length of test tube row, and first, the second backup pad is in closed condition, and a plurality of test tube rows are in order to place on first, the second backup pad with the mode of piling up from top to bottom, and first, the second bracing piece aims at the draw-in groove of penultimate floor test tube row both sides.
And secondly, the blending groove moves to the material receiving position below the supporting device, and the driving plate 112 is triggered, so that the first swing rod and the second swing rod are driven to swing towards the right, the first support rod and the second support rod are inserted into the clamping grooves on two sides of the test tube bank, and the test tube bank on the penultimate layer and above is supported.
And thirdly, the linear motor 120 is started, the first support plate and the second support plate are driven to rotate downwards through the slide block, the third swing rod and the fourth swing rod, and the unsupported bottommost test tube bank falls into the mixing groove to realize the layering purpose.
And fourthly, the linear motor 120 moves reversely, the first support plate and the second support plate are restored to be in a closed state, then the blending groove drives the test tube row to leave the material receiving position, the reset spring 111 drives the slide rod 109 to reset, the first swing rod and the second swing rod swing towards the second direction (towards the left), the first support rod and the second support rod are withdrawn from the clamping groove of the test tube row to reset, and the test tube row falls down on the support plate to be layered on the next step.
The separation device provided by the embodiment has the advantages of simple structure, low cost and easy realization; the connecting rod mechanism is not driven by an external power source, and can be driven by the moving force of other mechanisms as a power source for action, so that energy is saved; and the separation efficiency is high, the whole process is automatically carried out, the workload of manual operation can be greatly reduced, the efficiency is favorably improved, the working time is shortened, and the operation risk is reduced.
Blending device 200
Referring to fig. 7, there is shown a schematic perspective view of an embodiment of the blending device of the present invention, which includes a support 201, a blending tank 202, a blending motor 203, an electromagnetic locking device 204, a guide rail 205, a displacement motor 206, and a slide block 207.
The support 201 is used as a main structure for supporting the mixing groove 202, and is connected with the guide rail 205 in a sliding manner through the slider 207, and along with the driving of the displacement motor 206, the support 201 can drive the mixing groove to reciprocate along the guide rail 205, so as to realize the switching of the test tube rows among different stations.
The guide rail 205, the slider 207 and the displacement motor 206 constitute the claimed displacement device, but the displacement device may also be implemented by other known techniques to realize the displacement of the mixing channel.
The mixing tank 202 is preferably a cassette mechanism having a cavity for receiving the tube array and an opening for the tube array to enter and exit the cavity. The mixing groove is connected with the support 201 through a horizontal rotating shaft, one end of one rotating shaft is connected with a driving shaft of the mixing motor 203, and along with the driving of the mixing motor 203, the mixing groove can rotate around the horizontal rotating shaft relative to the support 201 to realize the mixing function. Meanwhile, the blending groove 202 can be fixed in a static state besides continuously rotating, and the embodiment at least includes three states: the opening is up, the opening is down and erect the state, and these three kinds of states correspond different functions respectively, for example realize the material loading of test tube row when the opening is up, realize the unloading of test tube row when the opening is down, realize the puncture of test tube when erectting the state, combine the removal that mixes the groove and can enlarge mixing device's application scope.
The invention also comprises a puncture device which is not shown, the puncture device is arranged on the moving path of the mixing groove, particularly at the tail end of the guide rail 205, the mixing groove 202 can firstly carry out the steps of feeding, mixing and the like at the head end of the guide rail 205, and after the mixing is finished, the mixing groove moves to the puncture device to carry out the puncture action of the test tube.
The mixing groove 202 is fixed in an upright state when moved, so that the test tubes therein are also in an upright state, and a plurality of puncture holes 2021 are provided at the top of the mixing groove 202 in this state, and the puncture holes 2021 are aligned with the test tubes in the test tubes, respectively, so that the puncture device performs a puncture operation.
Furthermore, the present invention further comprises a detecting device (not shown) and a code scanning device (not shown) disposed in front of the puncturing device, wherein the detecting device is used for detecting whether test tubes exist in the test tube row, and the code scanning device is used for performing code scanning identification on the test tubes.
It can be understood that the puncturing device, the detecting device and the code scanning device can be replaced by other functional devices according to requirements, so that the application range of the blending device is further expanded.
The blending tank locking device 204 is used for locking the blending tank to fix the blending tank in the current state or releasing the locking so that the blending tank can rotate freely. The locking device for the uniform mixing groove in the embodiment preferably adopts electromagnetic locking, and specifically comprises an electromagnet, a locking pin and a spring, wherein the locking pin is horizontally arranged, and the spring is sleeved on the locking pin. In an initial state, the spring acts on the blocking piece at the tail end of the locking pin, and the locking pin is in an unlocking state; after the electro-magnet circular telegram, thereby it adsorbs the separation blade and forces the locking round pin to insert the locking hole to mixing groove tip towards the left side, and the locking round pin is in the locking state this moment, and the spring takes place compression deformation, and after the electro-magnet outage, the locking round pin can reset under the effect of spring, resumes initial condition.
Referring to FIG. 8, which shows a side view of the mixing tank in an upright position, as shown, the present invention further includes a first sensor 208, a second sensor 209, and a third sensor 210 for detecting whether the mixing tank 202 is already open down, open up, and upright, respectively.
The blending device of the invention further comprises a test tube row locking device, which is shown in the schematic diagrams of the test tube row locking device in the clamping state and the opening state respectively by referring to fig. 9 and fig. 10, and the test tube row locking device comprises a hook 211 and a sliding rod 212.
The sliding rod 212 is preferably a long rod-shaped structure, which is disposed at the bottom of the mixing groove and can slide back and forth along the length direction, two grooves 2121 are symmetrically disposed on two sides of the sliding rod 212, in this embodiment, two groups of grooves 2121 are disposed and distributed along the length direction of the sliding rod 212, and specifically, the sliding rod includes a first groove disposed at the left end of the sliding rod 212 and a second groove disposed at the right end of the sliding rod 212, wherein the right end of the first groove is provided with a guiding inclined plane, the left end is an open end, and both ends of the second groove are provided with guiding inclined planes.
In addition, a strip hole 2122 is further formed in the center of the sliding rod 212, and a positioning strip 2123 is disposed at the right end of the sliding rod 212, and the positioning strip enables the sliding rod 212 to be in a T-shaped structure as a whole.
The hooks 211 are symmetrically disposed on both sides of the sliding rod 212, and have the same number as the grooves 2121, and can elastically move in a direction perpendicular to the sliding direction of the sliding rod 212. When the sliding rod 212 slides from the first position to the second position, the hooks 211 synchronously move in opposite directions, and the distance between the hooks 211 is not less than the width of the opening (as shown in fig. 10, or the length, such as when the hooks 211 are located at two short sides of the mixing groove); when the sliding rod slides from the second position to the first position, the hooks 211 move synchronously and oppositely, and the distance between the hooks is smaller than the width (or length) of the opening.
The hook 211 is fixed by a fixing seat 213, and specifically, the fixing seat 213 is provided with a through hole, and a driving rod (not shown) is inserted into the through hole and can slide along the axial direction. One end of the driving rod extends out to be abutted against the sliding rod 212, and the other end is connected with the clamping hook 211. The driving rod is sleeved with a first spring.
The mixing groove is also provided with a positioning piece 214 and a second spring 215, the positioning piece 214 is positioned at the right end of the mixing groove, the second spring 215 is positioned in a strip-shaped hole 2122 on the sliding rod 212, two ends of the second spring are respectively connected with the sliding rod 212 and the groove body of the mixing groove, the second spring 215 has a certain stretching amount in an initial state, and the second spring can enable a positioning strip 2123 at the right end of the sliding rod 212 to be abutted against the positioning piece 214, so that the initial state of the sliding rod 212 is fixed at a first position, and the clamping state is ensured to be the initial state of the clamping device; when the sliding rod 212 slides leftwards, the second spring 215 is further stretched to provide the power for resetting the sliding rod 212, so that the whole locking device only needs to provide the power for sliding the sliding rod without arranging an additional power source, the structure is simpler, and the cost is lower.
The working process of the blending device of the invention is as follows:
firstly, as shown in fig. 7, the blending groove 202 rotates to a state with an upward opening, the hooks 211 on both sides open, the test tube row falls into the blending groove 202 from the supporting device 100, and then the hooks 211 fold to lock the test tube row in the blending groove, so that the material receiving step is completed.
Secondly, the blending groove 202 rotates several circles continuously to blend the sample, and stays in an upright state after the first blending is completed, as shown in fig. 8.
Thirdly, support 201 and mixing groove 202 move along guide rail 205, pass through detection device in proper order and examine whether the position that the test tube row waited to puncture has the test tube, pass through after the detection again through sweeping yard device scanning bar code, move to piercing depth at last and carry out the puncture sample of first test tube, electromagnetism locking means 204 carries out the locking to mixing groove 202 when carrying out the puncture sample, avoids it to take place to rotate.
Fourthly, after the puncture sampling work of the first test tube is finished, the mixing groove 202 drives the test tube row to reset and carry out the second rotation mixing, and whether the detection, the bar code scanning and the puncture sampling of the second test tube are carried out continuously after the second mixing is finished.
Fifthly, repeating the steps in sequence until the puncture sampling work of all the test tubes is completed, resetting the mixing groove 202, rotating the mixing groove to a state that the opening faces downwards, opening the clamping hook 211 again, and enabling the test tube row to fall freely to realize the blanking step.
But trip automatic switch locking state and unblock state in above-mentioned embodiment, arrange the not good implementation of another kind of effect of locking means as the test tube, also can only have arrange the function of locking at the mixing inslot with the test tube, then combine the manual work to carry out the upper and lower material that the test tube was arranged, for example set up the shell fragment in the mixing inslot, the test tube is arranged and is supported the pressure shell fragment behind the entering mixing groove, fixes through the frictional force between shell fragment and the test tube row.
The repetition steps in the fourth step and the fifth step in the above embodiments are that only one puncture position is provided in the present embodiment, and the puncture device can puncture and sample only one test tube at a time; if the puncture device is provided with a plurality of puncture positions, a plurality of test tube puncture samples can be analyzed simultaneously, repeated steps of test tube rows can be correspondingly reduced, and the puncture sampling work of all test tubes is completed.
The mixing device provided by the embodiment can mix and move the test tubes in the test tube row together, does not need to take out the independent test tubes to finish the operation, has a simple structure, and reduces the failure rate; and the workload of operators is reduced, the efficiency is improved, and the cost is saved.
Discharge device 300
Referring to fig. 11, there is shown a schematic perspective view of an embodiment of the discharge apparatus of the present invention, including a discharge fork 301 and a flipping panel 302.
The material returning fork 301 can move along a straight line under the driving of the power assembly, so as to drive the test tube bank to move, the material returning fork comprises a horizontal first bearing plate 3011 and a vertical first limiting plate 3012 arranged at the head end of the first bearing plate 3011, a first accommodating space for placing the test tube bank is formed between the first limiting plate 3012 and the first bearing plate 3011, the test tube bank directly falls into the first accommodating space after falling from a first position (material returning position), and the material returning fork 301 drives the test tube bank to advance.
The material returning fork 301 adopts a sectional moving mode, the driving stroke of the material returning fork 301 comprises a first stroke for driving the test tube row to move to the turnover plate and a second stroke for driving the turned test tube row to move from the turnover plate to the discharging position, namely, the test tube row is firstly pushed to the turnover mechanism by the material returning fork 301 to turn over, and then pushed to the second position by the material returning fork 301 to be stored after turning over.
Further, in order to balance the stress, two sides of the material returning fork 301 are respectively provided with a group of first bearing plates 3011 and first limiting plates 3012.
The flip board 302 includes a second receiving board 3021 and a vertical third receiving board 3022 disposed at the tail end of the second receiving board 3021, a second accommodating space for accommodating the test tube bank is formed between the second receiving board 3021 and the third receiving board 3022, and the rotating shaft 303 is disposed at the connection position of the second receiving board and the third receiving board.
In this embodiment, the second receiving plate 3021 and the third receiving plate 3022 are disposed above the first receiving plate 3011, and in order to avoid interference between the driving mechanism and the turnover mechanism, a notch penetrating through the bottom of the second receiving plate 3021 and the third receiving plate 3022 is disposed on the second receiving plate 3021, and the height of the notch should meet the requirement: the material returning fork 301 can drive the test tube bank to pass through the turnover plate from the notch after the turnover plate is turned over.
The turning plate 302 is in a state before turning in fig. 11, and at this time, the head end of the second receiving plate 3021 preferably rests on the first receiving plate 3011 and is inclined relative to the first receiving plate 3011, so that the test tube bank can smoothly enter the second accommodating space.
In addition, the present invention further comprises a buffer platform 304 disposed at the second position for placing the tube row after the turning.
Referring to fig. 12 to 15, the working process of the discharging device of the present invention is as follows:
first, fig. 12 shows an initial state of the material returning device, in which the material returning fork 301 extends to the longest, the first accommodating space is at the first position, the test tube bank 400 falls from the upper blending tank onto the first receiving plate 3011, and the head end of the second receiving plate 3021 rests on the upper surface of the first receiving plate 3011 and is inclined with respect to the first receiving plate 3011.
Second, fig. 13 shows a state when the reject fork is at the first stroke end, after the test tube row 400 falls on the first receiving plate 3011, the reject fork 301 moves to the left side, the test tube row 400 is pushed onto the second receiving plate 3021, and the reject fork 301 pauses moving.
Fig. 14 shows a state after the inversion plate is turned over, after the test tube row 400 moves onto the second receiving plate 3021, the inversion plate rotates counterclockwise to erect the test tube row 400, at this time, the second receiving plate 3021 is in a vertical state, and the third receiving plate 3022 is in a horizontal state.
Fourthly, fig. 15 shows a state when the material returning fork is at the second stroke end, after the test tube row 400 is erected, the material returning fork 301 moves again, the notch on the turnover plate passes through the second receiving plate 3021 and drives the test tube row 400 to be separated from the turnover plate, and the test tube row is reset after being pushed to the second position (the buffer platform 304).
While the preferred embodiments of the present invention have been illustrated and described, it will be understood by those skilled in the art that various changes in form and details may be made therein without departing from the spirit and scope of the invention as defined by the appended claims.

Claims (10)

1. An automatic sample feeding device is characterized by comprising a sample separating device, a blending device and a discharging device, wherein the blending device is arranged below the sample separating device, the discharging device is arranged below the blending device, the sample separating device is used for separating an individual test tube row from a plurality of test tube rows for storing samples, the individual test tube row falls into the blending device and then is blended, and the test tube row falls into the discharging device at the blending device and then is discharged;
mixing device includes support and mixing groove, be equipped with the confession on the mixing groove the opening of test tube row business turn over, the mixing groove with the support is connected to can be relative around an axle center the support rotates, and this mixing groove can be fixed at opening up, opening down and the state of erectting at least, works as the material loading that the test tube was arranged can be realized to the opening in mixing groove when up, can realize the unloading that the test tube was arranged when the opening was down, the puncture of test tube can be realized when the mixing groove is in the state of erectting.
2. The autosampler device according to claim 1, wherein said sample separation device comprises a linkage mechanism and a support device arranged below said linkage mechanism, said support device comprising an openable support plate for receiving the rows of test tubes stacked in a vertical direction when closed and allowing the rows of test tubes to fall freely when opened; the connecting rod mechanism comprises a first supporting rod and a second supporting rod which are oppositely arranged, the first supporting rod and the second supporting rod can be relatively close to or separated from each other, the first supporting rod and the second supporting rod can support the test tube rows on the penultimate layer and above when the first supporting rod and the second supporting rod are relatively close to each other, and the test tube rows can be allowed to freely fall when the first supporting rod and the second supporting rod are relatively far away from each other.
3. The automatic sampling device according to claim 2, wherein the link mechanism comprises a first swing link, a second swing link, a first rotating shaft, a second rotating shaft and a sliding rod, wherein the first rotating shaft and the second rotating shaft are parallel to each other, one end of the first swing link and one end of the second swing link are respectively connected with the first rotating shaft and the second rotating shaft, the other end of the first swing link and the other end of the second swing link are respectively connected with the two ends of the sliding rod in a rotating manner, a first supporting rod and a second supporting rod are respectively connected to the first rotating shaft and the second rotating shaft through the swing links, the first swing link and the second swing link can swing in the same direction through the sliding rod, so as to respectively drive the first supporting rod and the second supporting rod to swing synchronously, the first supporting rod is located below the first rotating shaft, the second supporting rod is located above the second rotating shaft, and the first supporting rod and the second supporting rod are located in the same horizontal plane, when the first supporting, When the second swing rod swings towards a first direction, the first support rod and the second support rod are relatively close to each other, and when the first swing rod and the second swing rod swing towards an opposite second direction, the first support rod and the second support rod are relatively far away from each other.
4. The automatic sampling device according to claim 2, wherein the supporting device comprises a third rotating shaft, a fourth rotating shaft, a third oscillating bar, a fourth oscillating bar, a sliding block and a linear motor, the third rotating shaft and the fourth rotating shaft are parallel to each other and are respectively fixedly connected with the supporting plate, one ends of the third oscillating bar and one end of the fourth oscillating bar are respectively fixedly connected with the third rotating shaft and the fourth rotating shaft, the other ends of the third oscillating bar and the fourth oscillating bar are rotatably connected with the sliding block and can slide along the length direction of the sliding block relative to the sliding block, the sliding block can reciprocate along the vertical direction under the driving of the linear motor, and then the supporting plate is driven by the third oscillating bar and the fourth oscillating bar to reciprocate.
5. The autoinjection device of any one of claims 1-4, further comprising a displacement device and a puncture device, wherein the homogenizing device reciprocates through the displacement device, and the puncture device is disposed on a moving path of the displacement device.
6. The autosampler device according to claim 1, wherein said mixing tank is fixed in a vertical position during movement, and wherein a plurality of piercing holes are provided at the top of the mixing tank in this position, said piercing holes being aligned with the test tubes in the test tube row, respectively.
7. The automatic sampling device according to claim 1, comprising a slide bar and hooks, wherein the slide bar can slide back and forth along the length direction of the slide bar, the hooks are symmetrically buckled at two sides of the opening and can elastically move along the direction perpendicular to the sliding direction of the slide bar, when the mixing tank is fixed in the state that the opening faces downwards, the slide bar slides from a first position to a second position, the hooks synchronously move in opposite directions, and the distance between the hooks is not less than the width or the length of the opening; when the blending groove rotates, the sliding rod slides to the first position from the second position, the clamping hooks synchronously move in opposite directions, and the distance between the clamping hooks is smaller than the width or the length of the opening.
8. The automatic sampling device according to claim 7, comprising a first spring and a driving rod which are arranged corresponding to the hooks, wherein one end of the driving rod is abutted against the sliding rod, the other end of the driving rod is connected with the corresponding hook, the first spring is sleeved on the driving rod and is compressed when the hooks move reversely relative to the opposite hooks; grooves are symmetrically formed in the positions, abutted against the driving rod, of the two sides of the sliding rod, and when the sliding rod is located at the first position, the driving rod slides into the grooves; when the slide bar is at the second position, the driving rod slides out of the groove.
9. The automatic sampling device of any one of claims 1 to 4, wherein the discharging device comprises a material returning fork and a turnover plate, wherein the material returning fork is configured to drive the test tube row to move, the turnover plate is configured to drive the test tube row to turn over, and wherein a driving stroke of the material returning fork comprises a first stroke that drives the test tube row to move to the turnover plate and a second stroke that drives the turned test tube row to move from the turnover plate to a discharging position.
10. The automatic sample feeding device according to claim 9, wherein the material returning fork comprises a horizontal first bearing plate and a vertical first limiting plate arranged at the head end of the first bearing plate, and a first accommodating space for accommodating the test tube bank is formed between the first limiting plate and the first bearing plate; the overturning plate comprises a second bearing plate and a vertical third bearing plate arranged at the tail end of the second bearing plate, a second accommodating space for accommodating the test tube bank is formed between the second bearing plate and the third bearing plate, and a rotating shaft is arranged at the joint of the second bearing plate and the third bearing plate; the second accepts the board and the third accepts the board to locate first top of accepting the board, the second is accepted to be equipped with one and link up its bottom and the third on the board and is accepted the breach of board, first board and the first limiting plate of accepting can the second is accepted board and third and is accepted board upset back and is crossed this second by this breach and accept board and third and accept the board.
CN201610884853.5A 2016-10-10 2016-10-10 Automatic sample introduction device Active CN107918029B (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CN201610884853.5A CN107918029B (en) 2016-10-10 2016-10-10 Automatic sample introduction device
PCT/CN2017/093474 WO2018068549A1 (en) 2016-10-10 2017-07-19 Automatic sample introduction device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201610884853.5A CN107918029B (en) 2016-10-10 2016-10-10 Automatic sample introduction device

Publications (2)

Publication Number Publication Date
CN107918029A CN107918029A (en) 2018-04-17
CN107918029B true CN107918029B (en) 2021-04-16

Family

ID=61892393

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201610884853.5A Active CN107918029B (en) 2016-10-10 2016-10-10 Automatic sample introduction device

Country Status (2)

Country Link
CN (1) CN107918029B (en)
WO (1) WO2018068549A1 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109060661B (en) * 2018-09-03 2023-08-29 中国人民解放军陆军勤务学院 Ultraviolet-visible automatic sample injection cleaning equipment and control method
CN109387384B (en) * 2018-10-22 2023-12-29 绍兴文理学院元培学院 Automatic bidirectional counterforce frame
CN111487400A (en) * 2020-05-22 2020-08-04 南京岚煜生物科技有限公司 Time-resolved fluorescence immunoassay analyzer
CN111958295A (en) * 2020-08-21 2020-11-20 芜湖宏远汽车零部件有限公司 Axostylus axostyle loading attachment is used in automobile parts processing

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN204896714U (en) * 2015-06-29 2015-12-23 河北鑫乐医疗器械科技股份有限公司 Heparin tube automatic loading detection device

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6808304B2 (en) * 2002-08-27 2004-10-26 Dade Behring Inc. Method for mixing liquid samples using a linear oscillation stroke
CN1932514A (en) * 2006-09-30 2007-03-21 江西特康科技有限公司 Haematocyte analyzer feeding mode and automatic feeding device
CN103364577B (en) * 2012-03-29 2014-11-26 深圳市开立科技有限公司 Feeding and sampling device for hematology analyzer
WO2014048473A1 (en) * 2012-09-27 2014-04-03 Pz Cormay S.A. Method and device for delivering fluid sample to analyzing apparatus
CN103901220B (en) * 2014-04-02 2015-04-08 长春迪瑞医疗科技股份有限公司 Device for automatically clamping, shaking up and puncturing
CN104991080B (en) * 2015-05-26 2017-06-06 中山市创艺生化工程有限公司 A kind of sampling device of cellanalyzer
CN105383951B (en) * 2015-12-08 2018-01-16 苏州金艾特科技有限公司 A kind of test tube preparation device and method

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN204896714U (en) * 2015-06-29 2015-12-23 河北鑫乐医疗器械科技股份有限公司 Heparin tube automatic loading detection device

Also Published As

Publication number Publication date
CN107918029A (en) 2018-04-17
WO2018068549A1 (en) 2018-04-19

Similar Documents

Publication Publication Date Title
CN107918029B (en) Automatic sample introduction device
CN106383242B (en) Sample analyser
AU675228B2 (en) Device for the transfer, agitaton and sampling of blood products in tubes grouped in cassettes
US8470242B2 (en) Apparatus having improved gantry assembly suitable for use in a laboratory environment
CN102095841B (en) Automatic single sample introduction device of blood cell analyzer
CN103364577A (en) Feeding and sampling device for hematology analyzer
RU2009120619A (en) DEVICE AND METHOD FOR OPERATING TUBES, IN PARTICULAR, IN AN AUTOMATIC BLOOD ANALYSIS
CN103364255A (en) Blending device for hematology analyzer
CN109342753A (en) Sample transport apparatus
CN107913626B (en) Test tube row mixing device
CN219447716U (en) Upgraded coal sample storage cabinet
CN107913750B (en) Layering device for connecting rod mechanism and test tube rows
CN109297793A (en) All-in-one machine is dyed in film-making
CN112914735B (en) Separate storage structure, separate storing compartment and medical shallow
CN206038707U (en) Sample structure and multinomial mesh detector
CN103364256A (en) Dragging device for hematology analyzer
CN105259022B (en) One kind prevents the secondary impact device that drops hammer
CN210376314U (en) Sample placer for medicine inspection
CN218968216U (en) Feeding mechanism of bone marrow cell morphology analysis system
CN209247803U (en) Sample transport apparatus
CN221050880U (en) Frozen storage rack extracting device
CN206177972U (en) Sample analyzer
CN215218736U (en) Laboratory harmful gas monitoring devices
CN107913748B (en) Test tube row material returning device and mixing device
CN216178232U (en) Stirring rod blade rotary riveting mechanism

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant