CN107898984A - Neck-shoulder pain, lumbago and leg pain treatment plaster and preparation method thereof - Google Patents
Neck-shoulder pain, lumbago and leg pain treatment plaster and preparation method thereof Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9068—Zingiber, e.g. garden ginger
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/58—Reptiles
- A61K35/583—Snakes; Lizards, e.g. chameleons
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/62—Leeches; Worms, e.g. cestodes, tapeworms, nematodes, roundworms, earth worms, ascarids, filarias, hookworms, trichinella or taenia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/63—Arthropods
- A61K35/648—Myriapods, e.g. centipedes or millipedes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/282—Artemisia, e.g. wormwood or sagebrush
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8962—Allium, e.g. garden onion, leek, garlic or chives
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
Abstract
The invention belongs to technical field of Chinese medicine, and in particular to a kind of neck-shoulder pain, lumbago and leg pain treatment plaster and preparation method thereof.Neck-shoulder pain, lumbago and leg pain treatment plaster includes 40~60 parts of wormwood leaf, 10~12 parts of ginger, raw 80~120 parts of green onion, 40~60 parts of sky dragon in the present invention, 40~60 parts of earthworm, 20~40 parts of ground beetle, 20~40 parts of levisticum, 2~4 parts of Borneolum, 10~15 parts of Soil unit, 30~50 parts of the root of Dahurain angelica.The production method of neck-shoulder pain, lumbago and leg pain treatment plaster includes weighing in the present invention smash to pieces after the cleaning of above-mentioned part medicinal material after be mixed to get particle；Then alcohol is added into particle to be soaked twice；Then concentrated after mixing first-time filtrate, secondary filtrate and decoction liquor, it is spare to obtain ointment；Then wormwood leaf, ginger, raw green onion and Borneolum are weighed, is smashed to pieces after mixing, above-mentioned gained ointment is eventually adding and is uniformly mixed.The present invention can alleviate vascular tissue's compressing, release musculature spasm, alleviate and treat the neck-shoulder pain, lumbago and leg pain of whole body, reach the effect treated both principal and secondary aspect of disease, and also make it that medication is safer while active constituents of medicine content is lifted.
Description
Technical field
The invention belongs to technical field of Chinese medicine, and in particular to a kind of neck-shoulder pain, lumbago and leg pain treatment plaster and preparation method thereof.
Background technology
Neck-shoulder pain, lumbago and leg pain be mostly caused by chronic strain and aseptic inflammation with patient part pain, swelling even function by
It is limited to one group of disease of master.The initiation reason of neck-shoulder pain, lumbago and leg pain is mainly by following several：1st, acute injury of soft tissue；2nd, soft tissue
Chronic strain；3rd, allergy；4th, chill is raw etc..
Initial stage, neck-shoulder pain, lumbago and leg pain illness was often not very obvious, and onset is hidden, weight when light during pain during beginning, partly can be voluntarily
Alleviate, because without being recognized and being paid attention to by people, so as to usually miss the best opportunity for the treatment of because of ignorance.
Heel part illness is similar, and the existing therapeutic modality for neck-shoulder pain, lumbago and leg pain is roughly divided into three kinds：1st, Western medicine aids in
Treatment, mainly by reducing position hormone secretion, reducing neural sensitivity or even blocking the modes such as pain nerve to relieve pain, generation
Medicine administered to bring out the cold thing has brufen etc.；Usually suiting the medicine to the illness property is strong for this kind of lenitive mode, and universality is poor, and usually can be with acutely
Side effect and a variety of taboo use conditions.And due to former using the effects such as hormone secretion, reduction neural sensitivity are reduced
Reason, belongs to presentation treatment, is only capable of alleviating for the moment pain.2nd, operative treatment, mainly cuts off illness by way of surgical operation,
To reach radical cure effect, this therapeutic modality input is big, and is often associated with a variety of postoperative complications, belongs to one kind less than ten thousand
Have no alternative but the therapeutic modality that will not be used.3rd, traditional Chinese medicine therapy, by the rarity of Chinese civilization --- lunar physics technique, passes through one
A little row Chinese medicines or Chinese traditional massage skill and technique, comb the cause of disease, remove lesion, carry out health and support treatment, this therapeutic modality is gentle and fits
It is wide with scope, and be based on, by adjusting human body body self-ability, resisting the cause of disease, belonging to and treat both principal and secondary aspect of disease, therefore, this treatment
Mode is increasingly approved and is adopted by people, but treatment of this kind of mode for neck-shoulder pain, lumbago and leg pain, the maximum that presently, there are
Defect is that therapeutic effect is not good enough first, secondly Chinese herbal medicine utilization rate is low.
The content of the invention
In order to solve the above problem existing in the prior art, primary and foremost purpose of the invention is to provide one kind for neck, shoulder, waist and leg
Pain has the neck-shoulder pain, lumbago and leg pain treatment plaster of preferable therapeutic effect.On this basis, it is a further object of the present invention to provide a kind of high
The production method of the neck-shoulder pain, lumbago and leg pain treatment plaster of utilization rate, while further to lift the neck-shoulder pain, lumbago and leg pain treatment cream
The drug effect of medicine.
Present invention firstly provides a kind of neck-shoulder pain, lumbago and leg pain to treat plaster, is mainly made of the raw material of following parts by weight：
For the better healing of tissue injury type neck-shoulder pain, lumbago and leg pain, neck-shoulder pain, lumbago and leg pain of the invention treatment plaster further preferably wraps
Include the raw material of following parts by weight：
In order to further lift drug effect, neck-shoulder pain, lumbago and leg pain of the invention treatment plaster further preferably further includes following parts by weight
Raw material：15~25 parts of egg white, 10~16 parts of white wine.
Embodiment according to the present invention, neck-shoulder pain, lumbago and leg pain of the invention treat plaster preferably by following parts by weight
Raw material are made：
Based on above technical scheme, the present invention also provides the production method of neck-shoulder pain, lumbago and leg pain treatment plaster, including with
Lower step：
S1：Weigh and be mixed to get particle after being smashed to pieces after sky dragon, earthworm, ground beetle, levisticum, Soil unit and the root of Dahurain angelica clean, then
Alcohol is added into particle all to submerge in alcohol to particle, carries out first time immersion；
S2：Separation of solid and liquid is carried out after the completion of soaking for the first time, obtains first-time filtrate and a filter residue, is added into a filter residue
Enter water a to disintegrating slag all to submerge in water, carry out second and soak；
S3：Separation of solid and liquid is carried out after the completion of second of immersion, obtains secondary filtrate and secondary filter residue, is added into secondary filter residue
Enter water to be decocted, decoction finishes carry out separation of solid and liquid, obtains decoction liquor；
S4：Concentrated after first-time filtrate, secondary filtrate and decoction liquor are mixed, it is spare to obtain ointment；
S5：Wormwood leaf, ginger, raw green onion and Borneolum are weighed, is smashed to pieces after mixing, it is equal then to add ointment mixing obtained by step S4
It is even to treat plaster up to the neck-shoulder pain, lumbago and leg pain.
Embodiment according to the present invention, in order to further lift the treatment for tissue injury type neck-shoulder pain, lumbago and leg pain
Effect, production method of the invention further preferably comprise the following steps：In step S5 with smash to pieces after wormwood leaf, ginger, raw green onion and
Borneolum adds in ointment obtained by step S4 and also helps more paste together；It is described to help more paste to be prepared by following steps：
P1：Weigh 40~55 parts by weight dragon's blood, 20~30 parts by weight rhizomes of davallia, 10~15 parts by weight rheum officinales, 20~25 weights
Measure part arisacma consanguineum schott and 15~25 parts by weight are interrupted, be uniformly mixed after smashing to pieces and obtain batch mixing, 5 times of batch mixing weight of addition into batch mixing
Alcohol, be heated at reflux for the first time 2.3 it is small when, after being heated at reflux for the first time, carry out separation of solid and liquid, obtain first separation liquid and
First separation slag；
P2：The water of 10 times of separation slag weight are added into first separation slag, be heated at reflux for the second time 2.3 it is small when, the
After secondary back heats, separation of solid and liquid is carried out, obtains secondary separation liquid and secondary separation slag；
P3：Concentrated after first separation liquid and secondary separation liquid are mixed, obtain helping more first cream；
P4：Xiang Zhuyu just adds the native copper of 20~35 parts by weight in cream, be uniformly mixed described in obtaining and help more paste.
Embodiment according to the present invention, in order to further lift drug effect, described in production method of the invention
The relative density of ointment is preferably 1.2~1.4, described to help that more just the density of cream is preferably 1.1~1.3.
Embodiment according to the present invention, in order to further lift drug effect, in production method of the invention preferably
Comprise the following steps：Added together with wormwood leaf, ginger, raw green onion and Borneolum in step S5 after smashing to pieces in ointment obtained by step S4
Also have 15~25 parts by weight egg white and 10~16 parts by weight white wine.
Beneficial effects of the present invention are：
In the present invention, reconciled and compounded by each taste Chinese herbal medicine raw material, clearing damp uncharms, alleviates and treat pain, according to this
The embodiment of invention confirms, has good therapeutic effect for neck-shoulder pain, lumbago and leg pain.The neck-shoulder pain, lumbago and leg pain of the present invention is controlled
Vascular tissue's compressing can be alleviated by treating plaster, release musculature spasm, enhancing improves local blood circulation, and then alleviates and control
The neck-shoulder pain, lumbago and leg pain of whole body is treated, reaches the effect treated both principal and secondary aspect of disease, and it is applied widely.
In the present invention, the dragon's blood, the rhizome of davallia, native copper, rheum officinale, arisacma consanguineum schott and the discontinuously corresponding technical side that preferably add
Case, can play more preferable therapeutic effect to tissue damage class pain.Dragon's blood, the rhizome of davallia, native copper, rheum officinale, arisacma consanguineum schott and disconnected
It is continuous to cooperate, tissue repair hyperplasia can be promoted, repair traumatic wounds as early as possible.
In the present invention, the neck-shoulder pain, lumbago and leg pain that with the addition of egg white treats plaster during specifically used, can be steamed in advance
Heat treatment, treats to carry out application therapy again after albumen portion denaturation, each active ingredient excitation can be helped to enter the egg of half denaturation
Further enter in clear in human body, and then further lift therapeutic effect.Meanwhile the white wine synchronously added, on the one hand it is beneficial to
The further dissolving exudation of pharmacological property component, on the other hand since human body is stronger, Neng Gouyu for the absorbability of alcohol
Egg white cooperates to be made in the smooth human body of active ingredient as carrier.
In production method provided by the present invention, according to the physicochemical characteristics of each raw material, respectively by multi-level
Extracting method process, and then as far as possible extract the active chemical components in raw material.Applied with conventional directly medicinal powder
Compare, additionally it is possible to remove the toxicity of part raw material, also make it that medication is safer while active constituents of medicine content is lifted.
Embodiment
Further explaination is done to the present invention with reference to specific embodiment.
Embodiment 1：
The present embodiment provides a kind of neck-shoulder pain, lumbago and leg pain to treat plaster, is made of following raw material：Wormwood leaf 40g, ginger 10g,
Raw green onion 80g, sky dragon 40g, earthworm 40g, ground beetle 20g, levisticum 20g, Borneolum 2g, Soil unit 10g and root of Dahurain angelica 30g.
The specific production method of the neck-shoulder pain, lumbago and leg pain treatment plaster of the present embodiment is as follows：Weigh sky dragon, earthworm, ground beetle,
Particle is mixed to get after being smashed to pieces after levisticum, Soil unit and root of Dahurain angelica cleaning, alcohol that concentration is 50% is then added into particle to broken
Material is all submerged in alcohol, carries out first time immersion.Filtered after the completion of soaking for the first time, obtain first-time filtrate and a filter residue,
Water a to disintegrating slag is added into a filter residue all to submerge in water, is carried out second and is soaked.Filtered after the completion of second of immersion,
Secondary filtrate and secondary filter residue are obtained, 500ml water is added into secondary filter residue and is decocted, decoction finishes filtering, is decocted
Liquid.Will first-time filtrate, secondary filtrate and decoction liquor mix after concentrate, obtain that ointment is spare, the relative density of ointment is 1.2.Claim
Wormwood leaf, ginger, raw green onion and Borneolum are taken, is smashed to pieces after mixing, gained ointment is then added and is uniformly mixed up to the neck, shoulder, waist and leg
Pain treatment plaster.
Embodiment 2：
The present embodiment provides a kind of neck-shoulder pain, lumbago and leg pain to treat plaster, is made of following raw material：Wormwood leaf 60g, ginger 12g,
Raw green onion 120g, sky dragon 60g, earthworm 60g, ground beetle 40g, levisticum 40g, Borneolum 4g, Soil unit 15g and root of Dahurain angelica 50g.
The specific production method of the neck-shoulder pain, lumbago and leg pain treatment plaster of the present embodiment is as follows：Weigh sky dragon, earthworm, ground beetle,
Particle is mixed to get after being smashed to pieces after levisticum, Soil unit and root of Dahurain angelica cleaning, alcohol that concentration is 50% is then added into particle to broken
Material is all submerged in alcohol, carries out first time immersion.Filtered after the completion of soaking for the first time, obtain first-time filtrate and a filter residue,
Water a to disintegrating slag is added into a filter residue all to submerge in water, is carried out second and is soaked.Filtered after the completion of second of immersion,
Secondary filtrate and secondary filter residue are obtained, 1000ml water is added into secondary filter residue and is decocted, decoction finishes filtering, is decocted
Liquid.Will first-time filtrate, secondary filtrate and decoction liquor mix after concentrate, obtain that ointment is spare, the relative density of ointment is 1.4.Claim
Wormwood leaf, ginger, raw green onion and Borneolum are taken, is smashed to pieces after mixing, gained ointment is then added and is uniformly mixed up to the neck, shoulder, waist and leg
Pain treatment plaster.
Embodiment 3：
The present embodiment provides a kind of neck-shoulder pain, lumbago and leg pain to treat plaster, is made of following raw material：Wormwood leaf 60g, ginger 12g,
Raw green onion 120g, sky dragon 60g, earthworm 60g, ground beetle 40g, levisticum 40g, Borneolum 4g, Soil unit 15g and root of Dahurain angelica 50g；And dragon's blood
55g, rhizome of davallia 30g, native copper 35g, rheum officinale 15g, arisacma consanguineum schott 25g, interrupted 25g, egg white 25g and white wine 16g.
The specific production method of the neck-shoulder pain, lumbago and leg pain treatment plaster of the present embodiment is as follows：
Weigh and be mixed to get particle after being smashed to pieces after sky dragon, earthworm, ground beetle, levisticum, Soil unit and the root of Dahurain angelica clean, then to broken
The alcohol that concentration is 50% is added in material all to submerge in alcohol to particle, carries out first time immersion.After the completion of soaking for the first time
Filtering, obtains first-time filtrate and a filter residue, and water a to disintegrating slag is added into a filter residue and is all submerged in water, carries out second
Secondary immersion.Second soak after the completion of filter, obtain secondary filtrate and secondary filter residue, added into secondary filter residue 1000ml water into
Row decocts, and decoction finishes filtering, obtains decoction liquor.Concentrated after first-time filtrate, secondary filtrate and decoction liquor are mixed, obtain ointment
Spare, the relative density of ointment is 1.3.
Weigh dragon's blood, the rhizome of davallia, rheum officinale, arisacma consanguineum schott and discontinuously, after smashing to pieces be uniformly mixed obtain batch mixing, added into batch mixing
750ml volumetric concentrations be 75% alcohol, be heated at reflux for the first time 2.3 it is small when, be heated at reflux finish postcooling then for the first time
Filtering, obtains first separation liquid and first separation slag.The water of 10 times of separation slag weight is added into first separation slag, carries out second
It is secondary be heated at reflux 2.3 it is small when, be heated at reflux for the second time finish postcooling then filter, obtain secondary separation liquid and secondary separation
Slag.Concentrated after first separation liquid and secondary separation liquid are mixed, obtain helping more first cream, the relative density for helping more first cream is 1.25.
Xiang Zhuyu just adds native copper in cream, be uniformly mixed and obtain helping more paste.
Wormwood leaf, ginger, raw green onion and Borneolum are weighed, is smashed to pieces after mixing, then helps more cream together with egg white, white wine and gained
Agent adds gained ointment and is uniformly mixed up to neck-shoulder pain, lumbago and leg pain treatment plaster together.
Embodiment 4：
The present embodiment provides a kind of neck-shoulder pain, lumbago and leg pain to treat plaster, is made of following raw material：Wormwood leaf 60g, ginger 12g,
Raw green onion 120g, sky dragon 60g, earthworm 60g, ground beetle 40g, levisticum 40g, Borneolum 4g, Soil unit 15g and root of Dahurain angelica 50g；And dragon's blood
40g, rhizome of davallia 20g, native copper 20g, rheum officinale 10g, arisacma consanguineum schott 20g, interrupted 15g, egg white 15g and white wine 10g.
The specific production method of the neck-shoulder pain, lumbago and leg pain treatment plaster of the present embodiment is as follows：
Weigh and be mixed to get particle after being smashed to pieces after sky dragon, earthworm, ground beetle, levisticum, Soil unit and the root of Dahurain angelica clean, then to broken
The alcohol that concentration is 50% is added in material all to submerge in alcohol to particle, carries out first time immersion.After the completion of soaking for the first time
Filtering, obtains first-time filtrate and a filter residue, and water a to disintegrating slag is added into a filter residue and is all submerged in water, carries out second
Secondary immersion.Second soak after the completion of filter, obtain secondary filtrate and secondary filter residue, added into secondary filter residue 1000ml water into
Row decocts, and decoction finishes filtering, obtains decoction liquor.Concentrated after first-time filtrate, secondary filtrate and decoction liquor are mixed, obtain ointment
Spare, the relative density of ointment is 1.2.
Weigh dragon's blood, the rhizome of davallia, rheum officinale, arisacma consanguineum schott and discontinuously, after smashing to pieces be uniformly mixed obtain batch mixing, added into batch mixing
525ml volumetric concentrations are 75% alcohol, be heated at reflux for the first time 2 it is small when, be heated at reflux finish postcooling and then mistake for the first time
Filter, obtains first separation liquid and first separation slag.The water of 10 times of separation slag weight is added into first separation slag, is carried out second
Be heated at reflux 2 it is small when, be heated at reflux for the second time finish postcooling then filter, obtain secondary separation liquid and secondary separation slag.Will
Concentrated after first separation liquid and the mixing of secondary separation liquid, obtain helping more first cream, the relative density for helping more first cream is 1.1.Xiang Zhuyu
Native copper is added in first cream, is uniformly mixed and obtains helping more paste.
Wormwood leaf, ginger, raw green onion and Borneolum are weighed, is smashed to pieces after mixing, then helps more cream together with egg white, white wine and gained
Agent adds gained ointment and is uniformly mixed up to neck-shoulder pain, lumbago and leg pain treatment plaster together.
Embodiment 5：
The present embodiment provides a kind of neck-shoulder pain, lumbago and leg pain to treat plaster, is made of following raw material：Wormwood leaf 50g, ginger 11g,
Raw green onion 100g, sky dragon 50g, earthworm 50g, ground beetle 30g, levisticum 30g, Borneolum 3g, Soil unit 13g and root of Dahurain angelica 40g；And dragon's blood
50g, rhizome of davallia 16g, native copper 30g, rheum officinale 12g, arisacma consanguineum schott 22g, interrupted 23g, egg white 21g and white wine 13g.
The specific production method of the neck-shoulder pain, lumbago and leg pain treatment plaster of the present embodiment is as follows：
Weigh and be mixed to get particle after being smashed to pieces after sky dragon, earthworm, ground beetle, levisticum, Soil unit and the root of Dahurain angelica clean, then to broken
The alcohol that concentration is 50% is added in material all to submerge in alcohol to particle, carries out first time immersion.After the completion of soaking for the first time
Filtering, obtains first-time filtrate and a filter residue, and water a to disintegrating slag is added into a filter residue and is all submerged in water, carries out second
Secondary immersion.Second soak after the completion of filter, obtain secondary filtrate and secondary filter residue, added into secondary filter residue 1000ml water into
Row decocts, and decoction finishes filtering, obtains decoction liquor.Concentrated after first-time filtrate, secondary filtrate and decoction liquor are mixed, obtain ointment
Spare, the relative density of ointment is 1.28.
Weigh dragon's blood, the rhizome of davallia, rheum officinale, arisacma consanguineum schott and discontinuously, after smashing to pieces be uniformly mixed obtain batch mixing, added into batch mixing
615ml volumetric concentrations be 75% alcohol, be heated at reflux for the first time 2.5 it is small when, be heated at reflux finish postcooling then for the first time
Filtering, obtains first separation liquid and first separation slag.The water of 10 times of separation slag weight is added into first separation slag, carries out second
It is secondary be heated at reflux 2.5 it is small when, be heated at reflux for the second time finish postcooling then filter, obtain secondary separation liquid and secondary separation
Slag.Concentrated after first separation liquid and secondary separation liquid are mixed, obtain helping more first cream, the relative density for helping more first cream is 1.3.To
Help and native copper is more just added in cream, be uniformly mixed and obtain helping more paste.
Wormwood leaf, ginger, raw green onion and Borneolum are weighed, is smashed to pieces after mixing, then helps more cream together with egg white, white wine and gained
Agent adds gained ointment and is uniformly mixed up to neck-shoulder pain, lumbago and leg pain treatment plaster together.
Repetition makes the neck-shoulder pain, lumbago and leg pain treatment plaster of multiple batches of embodiment 5 and carries out compliance test result to it.
Experimental example
First, experimental method
Same batch rabbit 25 is taken, the items basic parameter such as weight is in consistent control level.The back of rabbit from
Hair is cut off at neck 3cm, the naked skin for leaking out 10cm × 3cm scopes, it is deep that 5cm long is longitudinally cut off in the skin middle position appeared
Up to the damage of muscle, exposed 1min, then arrives rabbit damage model to obtain the final product.25 rabbit through damage processing are divided into three groups,
First group is blank control group, and comprising 5 rabbit, 5 rabbit are without any processing；Second group is experimental group, includes 10
Rabbit, 10 rabbit carry out plaster in its damage location and stick, and interior plaster is using previous embodiment 5 in plaster
Neck-shoulder pain, lumbago and leg pain treats plaster, and first plaster steaming is handled before sticking, daily two patch；3rd group is chemical drug control group, comprising
10 rabbit, 10 rabbit take wind-expelling pain-stopping capsule, and (ordinary purchasing is from pharmacy, the limited public affairs of production firm's Shaanxi step-length pharmacy
Department).The wound recovery situation of first and third, seven day damage rabbit of observation, is listed in the table below 1, table 2 and table 3 successively respectively.
2nd, experimental result
Table 1
Table 2
Table 3
3rd, interpretation of result
1~table of analytical table 3 understands that neck-shoulder pain, lumbago and leg pain using the present invention treats the family that plaster is treated in experimental group
Rabbit, in terms of wound striking feedback, mutually has excellent therapeutic effect compared to blank control group the effect of experimental group, embodies
The present invention has good result in terms of analgesic, and phase is also had no time compared to the therapeutic effect of chemical drug experimental group and allowed more, even
Curative effect is more preferably.Further, in terms of embodying organization healing in red, swollen, oozing of blood, bleeding, suppuration etc., experimental group has blank control group
The tissue repair effect not possessed completely with chemical drug control group, the neck-shoulder pain, lumbago and leg pain treatment plaster for further embodying the present invention exist
While analgesic, there is good tissue repair effect, and then be more suitable for needing the treatment of the neck-shoulder pain, lumbago and leg pain of tissue repair.
On the basis of above zoopery, neck-shoulder pain, lumbago and leg pain of the invention treatment plaster has been also applied to clinical trial,
It further demonstrate the excellent curative effect of the neck-shoulder pain, lumbago and leg pain treatment plaster of the present invention, model case is as follows：
Case 1：Mr. Wang, male, 47 years old, when dropping from eminence tumble injury it is right foot cause " right calcaneus comminuted fracture ", patient refuses
Operation absolutely, neck-shoulder pain, lumbago and leg pain using the present invention treat plaster, and then a gypsum has been beaten in outside, and six neck shoulders have been gone up in two weeks
Pain in waist and lower extremities treats plaster, and two weeks checks X-ray film later：Fracture line obscures, and has torn gypsum open, can walk, by it not bitterly.
The present invention is not limited to above-mentioned preferred forms, anyone can show that other are various under the enlightenment of the present invention
The product of form, however, make any change in its shape or structure, it is every that there is skill identical or similar to the present application
Art scheme, is within the scope of the present invention.
Claims (8)
1. neck-shoulder pain, lumbago and leg pain treats plaster, it is characterised in that is mainly made of the raw material of following parts by weight：
2. neck-shoulder pain, lumbago and leg pain according to claim 1 treats plaster, it is characterised in that：Further include the former material of following parts by weight
Material：
3. neck-shoulder pain, lumbago and leg pain according to claim 2 treats plaster, it is characterised in that：Further include the former material of following parts by weight
Material：
15~25 parts of egg white, 10~16 parts of white wine.
4. neck-shoulder pain, lumbago and leg pain according to claim 3 treats plaster, it is characterised in that：By the raw material system of following parts by weight
Into：
5. the production method of the neck-shoulder pain, lumbago and leg pain treatment plaster described in a kind of claim 1, it is characterised in that including following step
Suddenly：
S1：Weigh and be mixed to get particle after being smashed to pieces after sky dragon, earthworm, ground beetle, levisticum, Soil unit and the root of Dahurain angelica clean, then to broken
Alcohol is added in material all to submerge in alcohol to particle, carries out first time immersion；
S2：Separation of solid and liquid is carried out after the completion of soaking for the first time, first-time filtrate and a filter residue is obtained, water is added into a filter residue
All submerged to a disintegrating slag in water, carry out second and soak；
S3：Separation of solid and liquid is carried out after the completion of second of immersion, secondary filtrate and secondary filter residue is obtained, water is added into secondary filter residue
Decocted, decoction finishes carry out separation of solid and liquid, obtains decoction liquor；
S4：Concentrated after first-time filtrate, secondary filtrate and decoction liquor are mixed, it is spare to obtain ointment；
S5：Wormwood leaf, ginger, raw green onion and Borneolum are weighed, is smashed to pieces after mixing, step S4 gained ointment is then added and is uniformly mixed i.e.
Obtain the neck-shoulder pain, lumbago and leg pain treatment plaster.
6. production method according to claim 5, it is characterised in that in step S5 with smash to pieces after wormwood leaf, ginger, life
Green onion and Borneolum add in ointment obtained by step S4 and also help more paste together；It is described help more paste by following steps prepare and
：
P1：Weigh 40~55 parts by weight dragon's blood, 20~30 parts by weight rhizomes of davallia, 10~15 parts by weight rheum officinales, 20~25 parts by weight
Arisacma consanguineum schott and 15~25 parts by weight are interrupted, are uniformly mixed after smashing to pieces and obtain batch mixing, the wine of 5 times of batch mixing weight is added into batch mixing
Essence, be heated at reflux for the first time 2.3 it is small when, after being heated at reflux for the first time, carry out separation of solid and liquid, obtain first separation liquid and one
Secondary separation slag；
P2：Into first separation slag add 10 times separation slag weight water, be heated at reflux for the second time 2.3 it is small when, for the second time
After being heated at reflux, separation of solid and liquid is carried out, obtains secondary separation liquid and secondary separation slag；
P3：Concentrated after first separation liquid and secondary separation liquid are mixed, obtain helping more first cream；
P4：Xiang Zhuyu just adds the native copper of 20~35 parts by weight in cream, be uniformly mixed described in obtaining and help more paste.
7. production method according to claim 6, it is characterised in that the relative density of the ointment is 1.2~1.4, institute
The density for stating cream at the beginning of helping more is 1.1~1.3.
8. production method according to claim 7, it is characterised in that in step S5 with smash to pieces after wormwood leaf, ginger, life
Green onion and Borneolum add in ointment obtained by step S4 together the egg white of 15~25 parts by weight and the white wine of 10~16 parts by weight.
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| CN201711227744.7A CN107898984A (en) | 2017-11-29 | 2017-11-29 | Neck-shoulder pain, lumbago and leg pain treatment plaster and preparation method thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
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| CN110585351A (en) * | 2019-10-22 | 2019-12-20 | 长垣仁济医院有限公司 | External-use bone-setting ointment and preparation method thereof |
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| JP2014114253A (en) * | 2012-12-11 | 2014-06-26 | Kaigen Pharma Co Ltd | Analgesic antiinflammatory composition containing crude drug |
| CN104147577A (en) * | 2014-08-27 | 2014-11-19 | 刘俊旭 | Plaster used for promoting generation of bone callus and treating fracture |
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