CN107890500A - 一种治疗鳞屑型足癣的药膏及其制备方法 - Google Patents

一种治疗鳞屑型足癣的药膏及其制备方法 Download PDF

Info

Publication number
CN107890500A
CN107890500A CN201711271325.3A CN201711271325A CN107890500A CN 107890500 A CN107890500 A CN 107890500A CN 201711271325 A CN201711271325 A CN 201711271325A CN 107890500 A CN107890500 A CN 107890500A
Authority
CN
China
Prior art keywords
parts
ointment
preparation
rattletop
coptis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201711271325.3A
Other languages
English (en)
Inventor
马建国
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CN201711271325.3A priority Critical patent/CN107890500A/zh
Publication of CN107890500A publication Critical patent/CN107890500A/zh
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236—Ligusticum (licorice-root)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/282—Artemisia, e.g. wormwood or sagebrush
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/489—Sophora, e.g. necklacepod or mamani
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A61K36/718—Coptis (goldthread)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/889—Arecaceae, Palmae or Palmaceae (Palm family), e.g. date or coconut palm or palmetto
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

本发明涉及一种治疗鳞屑型足癣的药膏及其制备方法，配方是由下述重量配比的原料组成：藁本100一10份，牛蒡子100一10份，升麻100一10份，山豆根100一10份，槟榔100一10份，黄连100一10份，青蒿100一10份，凡士林5000一400份。制备方法是：将藁本、牛蒡子、升麻、山豆根、槟榔、黄连、青蒿，共磨成细粉，过100目筛，然后入凡士林中充分调匀，即成，分装备用。有益效果是：通过在临床观察，药物直至病变部位后，较好发挥杀真菌疗癣止痒，滋润肌肤作用。患者用后均感舒适，坚持外搽，使鳞屑型角化性皮损逐渐消退，达到标本兼治良好效果。有效避免了西药制剂对肌肤造成的损害。

Description

一种治疗鳞屑型足癣的药膏及其制备方法
技术领域
本发明涉及一种中药药膏，具体为治疗鳞屑型足癣的药膏及其制备方法。
背景技术
鳞屑型足癣是常见多发皮肤病，除足背外，所有趾缝、足底、足侧、足跟，均可累及发生。鳞屑呈环状、鱼鳞样或小片形，色淡黄，不断脱落，不断发生。将鳞屑剥去后，其下皮肤正常或略显红色。由于日久不愈，趾缝或足跟皮肤角化过度，变厚，到冬季干燥时，发生裂隙，有少数患者四季均裂，伴有不同程度痒或痛感。
西药治疗此病，用克霉坐乳膏、硝酸咪康坐乳膏、水扬酸酒精、皮康王、皮康霜等。多数患者认为，外用上药后，杀霉菌滋润肌肤效果不著，且肌肤会相反更加干燥或痛感。因而迄今仍乏一种治疗鳞屑型足癣既有好的疗效，又方便实用外治中药膏。
发明内容
本发明目的，为解除鳞屑型足癣患者痛苦，按中医药理论观点，宜研制出一种有较好疗效，杀霉菌滋润保护肌肤中药膏外搽，为较好疗法。
本发明是这样实现的：一种治疗鳞屑型足癣的药膏，它是由下述重量配比的原料组成：藁本100一10份，牛蒡子100一10份，升麻100一10份，山豆根100一10份，槟榔100一10份，黄连100一10份，青蒿100一10份，凡士林5000一400份。
本发明所述的一种治疗鳞屑型足癣的药膏最佳配比范围是：藁本20份，牛蒡子20份，升麻20份，山豆根20份，槟榔20份，黄连20份，青蒿20份，凡士林800份。
本发明所述药膏的制备方法是：将藁本、牛蒡子、升麻、山豆根、槟榔、黄连、青蒿，共磨成细粉，过100目筛，然后将药粉入凡士林中充分调匀，即成治疗鳞屑型足癣的药膏，分装塑料盒中备用。-
本发明的用药依据及有益效果是：藁本，味辛，性温，气味香烈，外用可治癣疾。现代研究，藁本含挥发油，由藁本粉、双甲氧丙烯苯组成，对常见致病性皮肤癣菌，有较强抗菌作用；牛蒡子，味辛、苦，性寒，现代研究，对多种皮肤真菌有不同程度抑制作用；升麻，味甘、辛、微寒，现代研究，对多种皮肤真菌有较好抗菌作用；山豆根，味苦，性寒，对絮状表皮癣菌有抑制作用；槟榔，味苦、辛，性温，现代研究，有抗皮肤真菌作用；黄连，味苦，性寒，现代研究，主含小蘖硷、黄连硷，对多种致病性真菌有抑制作用；青蒿，味苦、辛，性寒，现代研究，对皮肤真菌有较好杀灭抑制作用。
此药膏因是选用中药制成，取其治疗鳞屑型足癣，通过在临床中观察，药物直至病变部位后，较好发挥杀真菌疗癣止痒，滋润肌肤作用。据患者用后反应，用后均感舒适，坚持外搽，使鳞屑型角化性皮损逐渐消退，达到标本兼治良好效果。有效避免了西药制剂对肌肤造成的损害，及皮损更加干燥副作用，无任何不适，患者均愿接受使用本药膏外用，且简便易行，不仅杀真菌止痒润肤，并对皮肤有保护作用。与西药治疗方法相比，确具一定优越性和实用价值。
药膏的使用方法：每日早晚各1次涂搽于皮损处，然后纱布包敷，至皮损全部消退，症状消失，皮肤恢复正常。
临床疗效观察
临床治疗71例，男53例，女18例，年龄28一74岁。所有病例均符合鳞屑型足癣诊断标准。
治疗效果：治愈：临床症状，体征消失，皮肤恢复正常。好转：症状明显减轻，皮损消退50%以上。治疗30天后进行疗效统计。
结果71例中，治愈60例，好转11例。
具体实施方式
下面用具体实施例来说明本发明的技术特征。
实施例1：藁本20g，牛蒡子20g，升麻20g，山豆根20g，槟榔20g，黄连20g，青蒿20g，凡士林800g。
该药膏的制备方法是：将藁本、牛蒡子、升麻、山豆根、槟榔、黄连、青蒿，共磨成细粉，过100目筛，然后将药份入凡士林中充分调匀，分装塑料盒中即可。
实施例2：藁本40g，牛蒡子40g，升麻40g，山豆根40g，槟榔40g，黄连40g，青蒿40g，凡士林2100g。
实施例3：藁本70g，牛蒡子70g，升麻70g，山豆根70g，槟榔70g，黄连70g，青蒿70g，凡士林3400g。，
该药膏的制备过程按上述实施例1制备过程加工即可。
从实践中对3个实施方案进行疗效比较，认为实施例1疗效优于实施例2、实施例3，所以实施例1为最佳实施例。

Claims (3)

1.一种治疗鳞屑型足癣的药膏，其特征是由下述重量配比的原料组成：藁本100一10份，牛蒡子100一10份，升麻100一10份，山豆根100一10份，槟榔100一10份，黄连100一10份，青蒿100一10份，凡士林5000一400份。
2.如权利要求1所述的药膏，其特征在于由下述重量配比的原料组成：藁本20份，牛蒡子20份，升麻20份，山豆根20份，槟榔20份，黄连20份，青蒿20份，凡士林800份。
3.如权利要求1或2所述的药膏制备方法，其特征在于至少包括如下步骤：将藁本、牛蒡子、升麻、山豆根、槟榔、黄连、青蒿，共磨成细粉，过100目筛，然后将药粉入凡士林中充分调匀，即成药膏。
CN201711271325.3A 2017-12-05 2017-12-05 一种治疗鳞屑型足癣的药膏及其制备方法 Pending CN107890500A (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201711271325.3A CN107890500A (zh) 2017-12-05 2017-12-05 一种治疗鳞屑型足癣的药膏及其制备方法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201711271325.3A CN107890500A (zh) 2017-12-05 2017-12-05 一种治疗鳞屑型足癣的药膏及其制备方法

Publications (1)

Publication Number Publication Date
CN107890500A true CN107890500A (zh) 2018-04-10

Family

ID=61807086

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201711271325.3A Pending CN107890500A (zh) 2017-12-05 2017-12-05 一种治疗鳞屑型足癣的药膏及其制备方法

Country Status (1)

Country Link
CN (1) CN107890500A (zh)

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1895385A (zh) * 2006-06-23 2007-01-17 程丽 治疗手足癣的中药水剂
CN105267811A (zh) * 2015-10-01 2016-01-27 陈鑫焱 一种治疗手足癣的外用颗粒剂及其制备方法和应用
CN105561098A (zh) * 2016-02-17 2016-05-11 蒋玉群 一种治疗糜烂性脚气的药物

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1895385A (zh) * 2006-06-23 2007-01-17 程丽 治疗手足癣的中药水剂
CN105267811A (zh) * 2015-10-01 2016-01-27 陈鑫焱 一种治疗手足癣的外用颗粒剂及其制备方法和应用
CN105561098A (zh) * 2016-02-17 2016-05-11 蒋玉群 一种治疗糜烂性脚气的药物

Similar Documents

Publication Publication Date Title
CN103463539A (zh) 一种治疗湿疹的药物及其制备方法和用途
CN106474350A (zh) 一种植物抗菌素复方喷剂及其制备方法
CN104840816A (zh) 一种预防和治疗痛风及高尿酸血症的复合超微粉及其制备方法
KR20160025187A (ko) 황백 추출물을 이용한 피부냉감용 생약조성물 및 이의 제조방법과 이를 이용한 피부개선제품
CN101152509A (zh) 一种治疗慢性咽炎的中药制剂的制备方法
CN112402522B (zh) 一种外治银屑病的中草药油剂
CN107890500A (zh) 一种治疗鳞屑型足癣的药膏及其制备方法
CN104740320A (zh) 一种治疗痤疮的中药组合物及其制备方法
CN107260844A (zh) 一种抑菌喷剂
CN101152546A (zh) 具有消炎、止痒和消毒杀菌功效的外用制剂及制法
KR20170023042A (ko) 황백 추출물을 이용한 피부냉감용 생약조성물 및 이의 제조방법과 이를 이용한 피부개선제품
CN108355124B (zh) 一种治疗气道粘液高分泌的中药组合物及其应用
CN102139062B (zh) 新型治疗咽炎、扁桃体炎的中药
CN104491635A (zh) 一种治疗足癣用中药组合物及其制备方法
CN111544419B (zh) 冠心病外用贴膏及其贴膜
CN104352557B (zh) 治疗湿热下注型带下病的苦参组合物
CN113197937B (zh) 一种预防、减轻或治疗放射性皮炎的组合物
CN108272960A (zh) 一种治疗痔病的中药组合物及其制备方法与用途
CN115645483B (zh) 组合物在制备治疗干性年龄相关性黄斑变性药物中的应用
CN114028487B (zh) 一种治疗急性软组织损伤的药物组合物及制剂
CN100333744C (zh) 一种治疗痤疮的药物
CN101926859B (zh) 一种治疗痔疮的中药组合物
CN105770278A (zh) 一种治疗鸡眼的中药膏
CN106581531A (zh) 一种治疗脚汗、脚臭的药物
CN105770205A (zh) 一种含有非洛地平的治疗高血压的药物组合物及其制备方法

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication
RJ01 Rejection of invention patent application after publication

Application publication date: 20180410