CN107841458B - Multilayer push type microorganism constant temperature drug sensitive incubator - Google Patents
Multilayer push type microorganism constant temperature drug sensitive incubator Download PDFInfo
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- CN107841458B CN107841458B CN201711168452.0A CN201711168452A CN107841458B CN 107841458 B CN107841458 B CN 107841458B CN 201711168452 A CN201711168452 A CN 201711168452A CN 107841458 B CN107841458 B CN 107841458B
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- 239000003814 drug Substances 0.000 title claims abstract description 21
- 229940079593 drug Drugs 0.000 title claims abstract description 21
- 244000005700 microbiome Species 0.000 title claims abstract description 13
- 238000010438 heat treatment Methods 0.000 claims abstract description 7
- 238000007789 sealing Methods 0.000 claims abstract description 4
- 238000001514 detection method Methods 0.000 claims description 17
- 239000010410 layer Substances 0.000 claims description 16
- 238000000034 method Methods 0.000 claims description 11
- 230000005540 biological transmission Effects 0.000 claims description 9
- 239000011229 interlayer Substances 0.000 claims description 8
- 238000000926 separation method Methods 0.000 claims description 4
- 230000000813 microbial effect Effects 0.000 claims 4
- 238000005119 centrifugation Methods 0.000 description 7
- 230000035945 sensitivity Effects 0.000 description 6
- 230000001580 bacterial effect Effects 0.000 description 3
- 238000012258 culturing Methods 0.000 description 3
- 230000000694 effects Effects 0.000 description 3
- 238000005507 spraying Methods 0.000 description 3
- 238000002815 broth microdilution Methods 0.000 description 2
- 230000007547 defect Effects 0.000 description 2
- 238000003745 diagnosis Methods 0.000 description 2
- 238000001085 differential centrifugation Methods 0.000 description 2
- 238000009792 diffusion process Methods 0.000 description 2
- 239000002245 particle Substances 0.000 description 2
- 238000004062 sedimentation Methods 0.000 description 2
- 206010059866 Drug resistance Diseases 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 244000052616 bacterial pathogen Species 0.000 description 1
- 230000003385 bacteriostatic effect Effects 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 230000003111 delayed effect Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000002289 effect on microbe Effects 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000000703 high-speed centrifugation Methods 0.000 description 1
- 238000009630 liquid culture Methods 0.000 description 1
- 238000000464 low-speed centrifugation Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 238000002558 medical inspection Methods 0.000 description 1
- 238000011206 morphological examination Methods 0.000 description 1
- 238000011369 optimal treatment Methods 0.000 description 1
- 230000007918 pathogenicity Effects 0.000 description 1
- 230000003014 reinforcing effect Effects 0.000 description 1
- 230000000405 serological effect Effects 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 238000011282 treatment Methods 0.000 description 1
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/34—Internal compartments or partitions
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/48—Holding appliances; Racks; Supports
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/52—Mobile; Means for transporting the apparatus
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- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M33/00—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
- C12M33/10—Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus by centrifugation ; Cyclones
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/12—Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature
- C12M41/14—Incubators; Climatic chambers
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
- C12M41/34—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of gas
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Abstract
The invention discloses a multilayer push type microorganism constant temperature drug sensitive incubator, which comprises a constant temperature incubator, a conveying box, a heating device and a control system, wherein the upper end and the lower end of the inner wall of the constant temperature incubator are provided with a main body of a rotating device through bearings, the rotating device is a whole formed by sequentially superposing and fixing a plurality of layers of annular cavities from top to bottom, each layer of annular cavity is uniformly divided into a plurality of independent units along the radial direction by a supporting plate, and each independent unit is used for accommodating a matched incubator after being numbered respectively; an internal driving cylinder mechanism is arranged in the hollow cavity. The shell of the conveying box is connected to the side wall of the constant temperature box at one side of the inlet and the outlet in a sealing way, and an external driving cylinder mechanism, a conveying mechanism and a detecting mechanism are arranged in the conveying box. The invention can realize the operation of putting in and extracting any culture box.
Description
Technical field:
the invention relates to the technical field of body fluid microorganism drug-sensitive culture detection instruments, in particular to a multilayer push type microorganism constant temperature drug-sensitive incubator.
The background technology is as follows:
in laboratory detection of bacterial animal epidemic diseases, bacterial morphological examination, separation culture, biochemical identification, pathogenicity test, serological examination and other diagnosis methods are generally adopted, and conventional drug sensitivity test is carried out on separated strains. The traditional special device for drug sensitivity culture and medical inspection of microorganisms, in particular to a device for rapidly culturing drug sensitivity and identifying trace continuous detection of mycobacteria, which is mainly implemented in a constant temperature environment, needs to observe for many times in the culture process and discover results as soon as possible, meanwhile, the liquid culture solution is easy to leak in the process of taking and transferring, the whole process can be completed through a plurality of steps, and excessive manpower and material resources can be consumed, and the degree of automation is low. The traditional method adopts a paper sheet diffusion method or a broth dilution method, wherein the paper sheet diffusion method can only qualitatively detect the drug sensitivity of the separated pathogenic bacteria, and the broth dilution method can quantitatively detect the minimum bactericidal concentration and the minimum bacteriostatic concentration of the drug. The method has the defects of higher requirement condition, complex operation and longer time consumption. The accurate diagnosis and the drug sensitivity result can be obtained only after more than five days, and before the drug sensitivity result is obtained, the treatment can be judged by the experience of clinical veterinarians, and the optimal treatment time is often delayed due to the wide existence of bacterial drug resistance, so that epidemic situation is repeated, out of control is caused, and the loss is huge.
The invention comprises the following steps:
aiming at the problems and the defects of the existing microorganism culture detection equipment at present, the invention provides a multilayer push type microorganism constant temperature drug-sensitive incubator capable of realizing a large number of concentrated cultures and independent taking out detection at any position.
The technical scheme is as follows: the multilayer push type microorganism constant temperature drug sensitive incubator comprises an incubator, a conveying box, a heating device and a control system, wherein the upper end and the lower end of the inner wall of the incubator are provided with a main body of a rotating device through bearings, and the main body of the rotating device is in transmission connection with a rotating driving motor; the rotating device is an integral body formed by sequentially superposing and fixing a plurality of layers of annular cavities from top to bottom, the middle part of the rotating device is a hollow cavity, each layer of annular cavity is uniformly divided into a plurality of independent units along the radial direction by the supporting plate, and each independent unit is used for accommodating a matched culture box after being numbered respectively; an inner screw rod and an inner slide rod are vertically arranged in the hollow cavity respectively, a nut pipe and a sliding sleeve are respectively fixed on an inner driving cylinder which is horizontally arranged in the hollow cavity, the nut pipe is arranged on the inner screw rod, the sliding sleeve is arranged on the inner slide rod, and the nut rod is in transmission connection with an inner stepping motor; the internal driving cylinder is provided with a position sensor or a code reader for identifying the layer height and the number of the independent unit; an inlet and an outlet are arranged on the side wall of the incubator at the side opposite to the piston rod of the inner drive cylinder.
The conveying box is characterized in that the outer shell of the conveying box is connected to the side wall of the constant temperature box at one side of the inlet and the outlet in a sealing way, an outer screw rod and an outer sliding rod are vertically arranged in the conveying box shell respectively, a nut pipe and a sliding sleeve are respectively fixed on an outer driving cylinder which is horizontally arranged in the hollow cavity, the nut pipe is arranged on the outer screw rod, the sliding sleeve is arranged on the outer sliding rod, and the nut rod is in transmission connection with an outer stepping motor; the external driving cylinder is provided with a position sensor or a code reader for identifying the layer height and the number of the independent unit; the piston rod of the external driving cylinder is opposite to the inlet and the outlet;
and a conveying mechanism is arranged in the area between the piston rod of the external driving cylinder and the inlet and the outlet, and a bracket of the conveying mechanism is fixed with the external driving cylinder.
The detection mechanism is arranged on the upper side of the conveying mechanism, the input end of the conveying mechanism is provided with an inlet, and the output end of the conveying mechanism is provided with an outlet. The code scanner is arranged on the detection mechanism support. The detection mechanism or the coding and coding device is fixed on the inner wall of the top of the conveying box or on a shell bracket of the external driving cylinder.
When the main body of the rotating device rotates, a gear ring is arranged on the lower side of the main body of the rotating device, a gear is arranged on a rotating shaft of a rotary driving motor fixed at the bottom of the constant temperature box, and the gear is meshed with the gear ring.
In addition, a sliding door capable of being sealed and a controllable push rod for driving the sliding door to open and close are arranged at the inlet and outlet positions of the side wall of the incubator. When all sliding doors are closed simultaneously through the controllable push rod, the main body of the rotating device can be driven at variable speed, and the differential centrifugal effect is realized. At least one interlayer is arranged in the middle of the culture box, and micropores are respectively arranged on the interlayer.
The beneficial effects are that: according to the invention, the incubator is firstly conveyed into different unit cavities of different layers of the incubator by using the conveying box, a large number of incubators can be accommodated by using the stacked multi-layer structure, and the purpose of separating and culturing can be realized by the rotation of the rotating device in the incubator culturing process. The incubator and the delivery box are matched with each other, so that the operation of putting in and extracting any incubator can be realized. The internal driving cylinder and the external driving cylinder can distribute the culture box to the unit cavity of any vacancy.
The invention can realize differential centrifugation effect on microorganisms, and gradually increases centrifugation speed or alternately performs low speed and high speed centrifugation when external output is required at the end of culture, so that particles with different sedimentation speeds are separated in batches at different centrifugation speeds and different centrifugation times. The culture box further realizes the purpose of separation detection through an interlayer and a micropore structure.
Drawings
Fig. 1 is a schematic cross-sectional structure of the present invention.
FIG. 2 is a schematic view of the cross-sectional structure A-A in FIG. 1.
Reference numerals in the drawings: 1 is a constant temperature box, 2 is a conveying box, 3 is a rotating device, 4 is an interlayer, 51 is an inner driving cylinder, 52 is an outer driving cylinder, 6 is a nut tube, 71 is an inner screw, 72 is an outer screw, 81 is an inner slide rod, 82 is an outer slide rod, 91 is an inner stepping motor, 92 is an outer stepping motor, 10 is a support, 11 is a hollow cavity, 12 is a detection mechanism support, 13 is a detection mechanism, 14 is a conveying mechanism, 15 is an inlet and outlet, 16 is an upper bearing, 17 is a lower bearing, 18 is a gear ring, 19 is a gear, 20 is a rotating driving motor, 21 is a supporting plate, 22 is a reinforcing plate, 23 is an inlet, 24 is an inclined baffle, 25 is an outlet, 26 is a culture box, 27 is a heating device, and 28 is a sliding sleeve.
The specific embodiment is as follows:
as shown in fig. 1 and 2, the multi-layer push type microorganism thermostatic drug-sensitive incubator comprises a constant temperature incubator 1 and a conveying incubator 2, a heating device, a control system and the like.
The incubator 1 has a cylindrical structure, and has a main body of the rotating device 3 mounted on the upper and lower ends of the inner wall thereof via an upper bearing 16 and a lower bearing 17, respectively. The rotating device 3 is an integral circular cylinder formed by sequentially overlapping and fixing a plurality of layers of annular cavities from top to bottom, and the central axis area of the rotating device is a hollow cavity. Each layer of annular cavity is divided into a plurality of independent units by supporting plates which are uniformly distributed along the radial direction. Each of the individual units is individually numbered for receiving a matched cassette 26, preferably with a labeled bar code or two-dimensional code disposed on the side wall of each individual unit.
The main body of the rotating device 3 is in transmission connection with a rotary drive motor 20. Specifically, a gear ring 18 is provided on the lower side of the main body of the rotating device 3 when the main body of the rotating device 3 rotates, and a gear 19 is mounted on the rotation shaft of a rotation driving motor 20 fixed to the bottom of the oven 1, and the gear 19 is engaged with the gear ring 18.
The heating means and the spraying means may be arranged inside the hollow cavity of the rotating means 3 or inside the oven 1 outside the rotating means 3. Sensor components such as a temperature sensor and a humidity sensor are provided in the oven 1. The connection of the sensor components such as the temperature sensor, the humidity sensor and the like and the input of the control system is used for detecting the culture condition in the incubator 1, and the control system controls the heating device to heat or controls the spraying device to heat and supplement humidity according to the change condition of the culture condition. Or, install the fan in incubator 1, can utilize the fan to realize convection current or introduce cold wind through the fan and adjust the temperature, perhaps reduce the temperature through the spraying. The control system is also used for controlling the rotation speed of the rotary driving motor 20 so as to realize variable speed driving of the rotary device 3.
Since the inlet and outlet 15 is arranged on the side wall of the incubator 1, when the rotating device 3 needs to be accelerated, a sliding door which can be sealed is also arranged at the position of the inlet and outlet 15 on the side wall of the incubator 1. Each sliding door can be connected into a whole, and a controllable push rod for driving the sliding door to open and close is arranged. And after all sliding doors are closed simultaneously by using a control system or manual control, the main body of the rotating device 3 is driven at variable speed, so that the differential centrifugal effect is realized. When the differential centrifugation effect on the microorganisms is needed to be output outwards at the end of the culture, the centrifugation speed is gradually increased or the low speed and the high speed are alternately adopted to carry out centrifugation, so that particles with different sedimentation speeds are separated in batches at different centrifugation speeds and different centrifugation times.
At least one interlayer is arranged in the middle of the culture box 26, and micropores are respectively arranged on the interlayer. The cartridge 26 further achieves the purpose of separation detection by a barrier and microporous structure.
The important components for driving each cassette 26 to move are by the cooperation of an inner drive cylinder 51 and an outer drive cylinder 52.
Specifically, an inner screw rod and an inner slide rod are vertically arranged in the hollow cavity respectively, a nut pipe and a sliding sleeve are respectively fixed on an inner driving cylinder 51 which is horizontally arranged in the hollow cavity, the nut pipe is arranged on the inner screw rod, the sliding sleeve is arranged on the inner slide rod, and the nut rod is in transmission connection with an inner stepping motor; the inner driving cylinder 51 is provided with a position sensor or a code reader for identifying the layer height and the number of the independent unit. An inlet and outlet 15 is arranged on the side wall of the incubator 1 on the side opposite to the piston rod of the inner drive cylinder 51.
The shell of the conveying box 2 is connected to the side wall of the constant temperature box 1 at one side of the inlet and outlet 15 in a sealing way, an outer screw rod and an outer slide rod are respectively vertically arranged in the shell of the conveying box 2, a nut pipe and a sliding sleeve are respectively fixed on an outer driving cylinder 52 which is horizontally arranged in the hollow cavity, the nut pipe is arranged on the outer screw rod, the sliding sleeve is arranged on the outer slide rod, and the nut rod is in transmission connection with an outer stepping motor; the outer driving cylinder 52 is provided with a position sensor or a code reader for identifying the layer height and the number of the independent unit; the piston rod of the external driving cylinder 52 is opposite to the inlet and outlet 15.
The incubator 1 and the transport box 2 cooperate with each other to enable the loading and unloading operation of any one of the culture cassettes 26. Wherein the inner drive cylinder 51 and the outer drive cylinder 52 are capable of dispensing the cartridge 26 to any empty cell cavity.
Meanwhile, a conveying mechanism 14 is arranged in a region between a piston rod of the external driving cylinder 52 and the inlet and outlet 15, and a bracket of the conveying mechanism 14 is fixed with the external driving cylinder 52.
It is also necessary to provide a detection mechanism 13 above the conveying mechanism 14, an inlet at the input end of the conveying mechanism 14, and an outlet at the output end of the conveying mechanism 14. The code scanner is arranged at the inlet of the conveying mechanism 14, and the code scanner is arranged on the bracket of the detecting mechanism 13. The detection mechanism 13 or the coding encoder is fixed on the inner wall of the top of the conveying box 2 or on a shell bracket of the outer driving cylinder 52.
Claims (6)
1. The multilayer push type microorganism constant temperature drug sensitive incubator comprises an incubator, a conveying box, a heating device and a control system, wherein the upper end and the lower end of the inner wall of the incubator are provided with a main body of a rotating device through bearings, and the main body of the rotating device is in transmission connection with a rotating driving motor; the rotating device is an integral body formed by sequentially superposing and fixing a plurality of layers of annular cavities from top to bottom, the middle part of the rotating device is a hollow cavity, each layer of annular cavity is uniformly divided into a plurality of independent units along the radial direction by the supporting plate, and each independent unit is used for accommodating a matched culture box after being numbered respectively; the method is characterized in that: an inner screw rod and an inner slide rod are vertically arranged in the hollow cavity respectively, a nut pipe and a sliding sleeve are respectively fixed on an inner driving cylinder which is horizontally arranged in the hollow cavity, the nut pipe is arranged on the inner screw rod, the sliding sleeve is arranged on the inner slide rod, and the nut rod is in transmission connection with an inner stepping motor; the internal driving cylinder is provided with a position sensor or a code reader for identifying the layer height and the number of the independent unit; an inlet and an outlet are arranged on the side wall of the incubator at the side opposite to the piston rod of the inner drive cylinder; the conveying box is characterized in that the outer shell of the conveying box is connected to the side wall of the constant temperature box at one side of the inlet and the outlet in a sealing way, an outer screw rod and an outer sliding rod are vertically arranged in the conveying box shell respectively, a nut pipe and a sliding sleeve are respectively fixed on an outer driving cylinder which is horizontally arranged in the hollow cavity, the nut pipe is arranged on the outer screw rod, the sliding sleeve is arranged on the outer sliding rod, and the nut rod is in transmission connection with an outer stepping motor; the external driving cylinder is provided with a position sensor or a code reader for identifying the layer height and the number of the independent unit; a conveying mechanism is arranged in the area between the piston rod of the external driving cylinder and the inlet and the outlet, and a bracket of the conveying mechanism is fixed with the external driving cylinder; the detection mechanism is arranged on the upper side of the conveying mechanism, the input end of the conveying mechanism is provided with an inlet, and the output end of the conveying mechanism is provided with an outlet; the piston rod of the external driving cylinder is opposite to the inlet and the outlet; the incubator is fed into different unit cavities of different layers of the incubator by utilizing the conveying box, a large number of incubators can be accommodated by utilizing the stacked multilayer structure, separation culture can be realized through rotation of the rotating device in the incubator in the culture process, the incubator and the conveying box are mutually matched to realize the putting-in and extracting operation of any incubator, and the inner driving cylinder and the outer driving cylinder can distribute the incubators for unit cavities of any vacancy.
2. The multi-layered push type microbial isothermal drug sensitive incubator according to claim 1, characterized in that: the code scanner is arranged on the detection mechanism support.
3. The multilayer push type microorganism thermostatic drug sensitive incubator according to claim 1 or 2, characterized in that: the detection mechanism or the coding and coding device is fixed on the inner wall of the top of the conveying box or on a shell bracket of the external driving cylinder.
4. The multi-layered push type microbial isothermal drug sensitive incubator according to claim 1, characterized in that: the gear ring is arranged on the lower side of the main body of the rotating device, a gear is arranged on a rotating shaft of a rotary driving motor fixed at the bottom of the constant temperature box, and the gear is meshed with the gear ring.
5. The multi-layered push type microbial isothermal drug sensitive incubator according to claim 1, characterized in that: the inlet and outlet positions of the side wall of the incubator are also provided with a sliding door capable of being sealed and a controllable push rod for driving the sliding door to open and close.
6. The multi-layered push type microbial isothermal drug sensitive incubator according to claim 1, characterized in that: at least one interlayer is arranged in the middle of the culture box, and micropores are respectively arranged on the interlayer.
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CN108998370A (en) * | 2018-09-18 | 2018-12-14 | 安图实验仪器(郑州)有限公司 | The susceptibility automatic incubation system of microorganism |
CN109856398B (en) * | 2019-01-31 | 2022-04-29 | 京东方科技集团股份有限公司 | Vaccine detection device and detection method thereof |
CN110711617B (en) * | 2019-10-30 | 2020-09-01 | 浙江达普生物科技有限公司 | Heating system for continuous inspection operation |
CN114107039B (en) * | 2022-01-28 | 2022-06-24 | 珠海迪尔生物工程股份有限公司 | Microorganism drug sensitivity analyzer |
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JP2004166554A (en) * | 2002-11-19 | 2004-06-17 | Sanyo Electric Co Ltd | Incubator |
CN102174395A (en) * | 2011-01-30 | 2011-09-07 | 中国科学院广州生物医药与健康研究院 | Automation augmentation and culture system of induced pluripotent stem cells |
CN102378945A (en) * | 2008-12-23 | 2012-03-14 | 佐马技术有限公司 | Flexible manufacturing system |
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US20090274348A1 (en) * | 2008-04-30 | 2009-11-05 | Ortho-Clinical Diagnostics, Inc. | Immunodiagnostic test apparatus having at least one imager to provide agglutination evaluations during centrifugration cycle |
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Publication number | Priority date | Publication date | Assignee | Title |
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JP2004166554A (en) * | 2002-11-19 | 2004-06-17 | Sanyo Electric Co Ltd | Incubator |
CN102378945A (en) * | 2008-12-23 | 2012-03-14 | 佐马技术有限公司 | Flexible manufacturing system |
CN102174395A (en) * | 2011-01-30 | 2011-09-07 | 中国科学院广州生物医药与健康研究院 | Automation augmentation and culture system of induced pluripotent stem cells |
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