CN107837376A - A kind of hemostasis and pain-relieving gel and preparation method thereof - Google Patents
A kind of hemostasis and pain-relieving gel and preparation method thereof Download PDFInfo
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- CN107837376A CN107837376A CN201711148871.8A CN201711148871A CN107837376A CN 107837376 A CN107837376 A CN 107837376A CN 201711148871 A CN201711148871 A CN 201711148871A CN 107837376 A CN107837376 A CN 107837376A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9068—Zingiber, e.g. garden ginger
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/36—Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/489—Sophora, e.g. necklacepod or mamani
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/62—Nymphaeaceae (Water-lily family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/889—Arecaceae, Palmae or Palmaceae (Palm family), e.g. date or coconut palm or palmetto
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
Abstract
The invention belongs to pharmaceutical technology field, more particularly to a kind of hemostasis and pain-relieving gel and preparation method thereof, it is made by the raw material of following portions by weight：5 20 parts of dalbergia wood, 8 20 parts of rhizoma nelumbinis, 3 15 parts of crinis trachycarpi, 3 12 parts of carbonized hair, 4 10 parts of the Fructus Sophorae, 2 10 parts of baked ginger, 4 10 parts of hedgehog skin, 20 70 parts of sheep hoof, the present invention carrys out cooling blood and hemostasis by monarch drug in a prescription of sheep hoof, dalbergia wood, rhizoma nelumbinis are ministerial drug to relieve pain stagnation resolvation, myogenic is restrained using crinis trachycarpi, carbonized hair, the Fructus Sophorae, hedgehog skin as adjutant, using baked ginger to make medicine come warming channel for arresting bleeding, warm in pain.All medicine compatibilities are reasonable, have cooling blood and hemostasis, analgesic stagnation resolvation, convergence myogenic, the effect of warm in pain, hemostasis and pain-relieving is fast, good effect, short treating period, has no toxic side effect.
Description
Technical field
The invention belongs to pharmaceutical technology field, more particularly to a kind of hemostasis and pain-relieving gel and preparation method thereof.
Background technology
In daily life, cause to bleed because extraneous factor usually makes skin cause accidental damage, bleed few, because
Fray the skin corium bleeding of body surface, general wound can oneself healing, and when bleeding is more, when body self-healing is difficult to stop blooding, just need
Want external used medicine to coordinate to be stopped blooding.Extraneous medicine can accelerate platelet aggregation to the edge of wound, and entangled to each other, make blood
Liquid accelerates solidification, in wound, produces fibrin.Existing hemostasis and pain-relieving gel respectively has advantage and disadvantage, and its performance still needs to be carried
It is high, it is therefore desirable to strengthen the research to this ten thousand face, meet the needs of patient.
The content of the invention
It is an object of the invention to provide a kind of hemostasis and pain-relieving gel and preparation method thereof.
The object of the present invention is achieved like this：A kind of hemostasis and pain-relieving gel, it is characterised in that it is by following weight parts
Several raw materials are formulated：Dalbergia wood 5-20 parts, rhizoma nelumbinis 8-20 parts, crinis trachycarpi 3-15 parts, carbonized hair 3-12 parts, Fructus Sophorae 4-10 parts,
Baked ginger 2-10 parts, hedgehog skin 4-10 parts, sheep hoof 20-70 parts.
A kind of hemostasis and pain-relieving gel, it is characterised in that：It is formulated by the raw material of following portions by weight：Dalbergia wood 9-15
Part, rhizoma nelumbinis 10-15 parts, crinis trachycarpi 5-10 parts, carbonized hair 5-9 parts, Fructus Sophorae 6-9 parts, baked ginger 3-9 parts, hedgehog skin 6-9 parts, sheep hoof
30-60 parts.
A kind of hemostasis and pain-relieving gel, it is characterised in that：It is formulated by the raw material of following portions by weight：Dalbergia wood 10
Part, 12 parts of rhizoma nelumbinis, 8 parts of crinis trachycarpi, 7 parts of carbonized hair, 7 parts of the Fructus Sophorae, 5 parts of baked ginger, 7 parts of hedgehog skin, 50 parts of sheep hoof.
A kind of preparation method of hemostasis and pain-relieving gel, it is characterised in that：Its preparation method is as follows：
Step 1）, 10 parts of dalbergia wood, 12 parts of rhizoma nelumbinis, 8 parts of crinis trachycarpi, 7 parts of carbonized hair, the Fructus Sophorae are taken according to the parts by weight of the raw material
7 parts, 5 parts of baked ginger, 7 parts of hedgehog skin, 50 parts of sheep hoof, after washing carry out moist heat sterilization 10min-20min, then dried in dryer
Dry 10min-20min, drying temperature is 25 DEG C -35 DEG C, finally by the dalbergia wood of drying, rhizoma nelumbinis, crinis trachycarpi, carbonized hair, the Fructus Sophorae, big gun
Ginger, hedgehog skin, sheep hoof are put into pulverizer, are ground into 50-100 mesh powders, and active compound powder is made, standby；
Step 2）, take 300 parts of 10 parts of carragheen, 20 parts of glycerine, 12 parts of polyoxyethylene sorbitan monoleate and distilled water, by 10 parts of carragheen
5-10 minutes are soaked in 20 parts of glycerine, 300 parts of distilled water is then added, is heated to 80 DEG C -100 DEG C, heats while stirring,
30 DEG C -40 DEG C are subsequently cooled to, 12 parts of polyoxyethylene sorbitan monoleates is added, stirs, room temperature is cooled to and gel forming agent is made；
Step 3）, by step 1）The active compound powder of acquisition and step 2）Obtained gel forming agent presses 1：0.05-1：0.1 ratio
Mixing, and stir, you can obtain described hemostasis and pain-relieving gel.
The present invention has no toxic side effect, and the medicine pharmacology in used formula is：
Dalbergia wood：It is pungent, temperature.Return liver, the spleen channel.For spitting blood, bleeding from five sense organs or subcutaneous tissue, traumatism and bleeding, liver-depressed hypochondrium pain, obstruction of qi in the chest shouting pain, the pain of injury caused by falling and tumbling, vomit
Tell stomachache.
Rhizoma nelumbinis：It is sweet, puckery, put down.Return liver, lung, stomach.Astringing to arrest bleeding, stagnation resolvation.For spitting blood, spitting of blood, bleeding from five sense organs or subcutaneous tissue, hematuria, collapse
Leakage.《Book on Chinese herbal medicine is looked for the truth》Record：Rhizoma nelumbinis puckery.With dried rhizome of rehmannia juice boys' urine.Kind only all hematemesis mass formed by blood stasis.Avoid iron.
Crinis trachycarpi：It is bitter, puckery, it is mild-natured.Return liver warp, lung channel, large intestine channel.For spitting blood, bleeding from five sense organs or subcutaneous tissue, have blood in stool, the card such as uterine bleeding.Convergence
Hemostasis：Cure mainly spitting of blood, haematemesis, bleeding from five sense organs or subcutaneous tissue, have blood in stool, uterine bleeding, the card such as menorrhalgia and without the stagnant person of the stasis of blood.
Carbonized hair：Hardship, put down.Return liver, stomach.Astringing to arrest bleeding, stagnation resolvation, diuresis.For spitting blood, spitting of blood, bleeding from five sense organs or subcutaneous tissue, blood strangury, urine
Blood, have blood in stool, uterine bleeding, traumatism and bleeding, difficult urination.
The Fructus Sophorae：Bitter, it is cold in nature.Return liver, large intestine channel.Clearing heat-fire, cooling blood and hemostasis.Had blood in stool for intestines heat, hemorrhoid swell bleeding, liver
Heat headache, dizziness hot eyes.《Essentials of Materia Medica》：" pure the moon of bitter cold.Enter Liver Channel qi leel.Dispelling wind heat, profit liver is dry, cool large intestine.Control unhappy wind
Dizzy, hemorrhoid blood intestines wind, the erosion of vulva is wet to itch, and improving eyesight stops tear, permanent tooth crow moustache, desinsection induced abortion.List and five sub- persons are gone, copper mallet mallet is broken, cow's milk
Mix steaming.Sophora flower hardship is cool, enter liver, large intestine blood system and cool blood.Wind-heat hot eyes is controlled, it is red to let out dysentery in vain, five hemorrhoid intestines winds, tell and collapse all blood ".
Baked ginger：It is pungent, heat.Returns spleen, stomach, kidney channel.Warming channel for arresting bleeding, warm in pain.Lost blood for the deficiency of yang, hematemesis uterine bleeding, taste
The cold of insufficiency type, stomachache are vomited and diarrhoea.《Herbal lease making》：Arduous big heat, in being kept except stomach is cold and bushing gas, internal organs of dispelling it is heavy it is cold plug with molten metal cold, go to dislike and give birth to
Newly, it is absolutely not positive that arteries and veins can be returned, draw blood medicine enter liver again and green blood is brought down a fever, black supplemental provisions are regarded it as and enter kidney dispellieg cold and dampness.
Hedgehog skin：It is bitter, sweet, it is mild-natured.Return stomach, large intestine, kidney channel.Blood-activating analgetic, astringing to arrest bleeding, controlling nocturnal emission with astringent drugs.For pain of gastric cavity
Bitterly, uterine hemorrhage, have blood in stool, discharging fresh blood stool, prolapse of the anus, hemorrhoid, seminal emission, the enuresis.
Sheep hoof：Bitter, acid, trembles with fear.It is clearing heat and detoxicating, hemostasis, defaecation, desinsection.It is small for nosebleed, functional uterine bleeding, blood
Plate reduction property purpura, chronic hepatitis, perianal is scorching, constipation；External piles is controlled in external application, acute mastitis, impetigo, furuncle,
Psoriasis.
The present invention is that monarch drug in a prescription carrys out cooling blood and hemostasis using sheep hoof, and dalbergia wood, rhizoma nelumbinis relieve pain stagnation resolvation for ministerial drug, more than crinis trachycarpi, blood
Charcoal, the Fructus Sophorae, hedgehog skin are that adjutant restrains myogenic, using baked ginger to make the medicine come warming channel for arresting bleeding, warm in pain.All medicine compatibilities are reasonable,
With cooling blood and hemostasis, analgesic stagnation resolvation, convergence myogenic, the effect of warm in pain, hemostasis and pain-relieving is fast, good effect, short treating period, nontoxic pair
Effect.
Embodiment
Embodiment 1：A kind of hemostasis and pain-relieving gel, it is formulated by the raw material of following portions by weight：10 grams of dalbergia wood, lotus root
12 grams of section, 8 grams of crinis trachycarpi, 7 grams of carbonized hair, 7 grams of the Fructus Sophorae, 5 grams of baked ginger, 7 grams of hedgehog skin, 50 grams of sheep hoof.
A kind of preparation method of hemostasis and pain-relieving gel, it is characterised in that：Its preparation method is as follows：
Step 1）, 10 grams of dalbergia wood, 12 grams of rhizoma nelumbinis, 8 grams of crinis trachycarpi, 7 grams of carbonized hair, the Fructus Sophorae are taken according to the parts by weight of the raw material
7 grams, 5 grams of baked ginger, 7 grams of hedgehog skin, 50 grams of sheep hoof, after washing carry out moist heat sterilization 15min, then dried in dryer
15min, drying temperature is 30 DEG C, finally by the dalbergia wood of drying, rhizoma nelumbinis, crinis trachycarpi, carbonized hair, the Fructus Sophorae, baked ginger, hedgehog skin, sheep
Hoof is put into pulverizer, is ground into 55 mesh powders, and active compound powder is made, standby；
Step 2）, take 300 parts of 10 parts of carragheen, 20 parts of glycerine, 12 parts of polyoxyethylene sorbitan monoleate and distilled water, by 10 parts of carragheen
5-10 minutes are soaked in 20 parts of glycerine, 300 parts of distilled water is then added, is heated to 80 DEG C -100 DEG C, heats while stirring,
30 DEG C -40 DEG C are subsequently cooled to, 12 parts of polyoxyethylene sorbitan monoleates is added, stirs, room temperature is cooled to and gel forming agent is made；
Step 3）, by step 1）The active compound powder of acquisition and step 2）Obtained gel forming agent presses 1：0.08 ratio mixing,
And stir, you can obtain described hemostasis and pain-relieving gel.
The present invention is right because experimental data is more in the present invention to medicinal material progress prescription from medicinal material with tcm theory
Formula is repeatedly adjusted and tested, and is only listed 8 groups of higher prescriptions of curative effect herein and is contrasted with inventive formulation.
Experiment is as follows：
Formula 1：12 grams of rhizoma nelumbinis, 8 grams of crinis trachycarpi, 7 grams of carbonized hair, 7 grams of the Fructus Sophorae, 5 grams of baked ginger, 7 grams of hedgehog skin, 50 grams of sheep hoof.
Formula 2：10 grams of dalbergia wood, 8 grams of crinis trachycarpi, 7 grams of carbonized hair, 7 grams of the Fructus Sophorae, 5 grams of baked ginger, 7 grams of hedgehog skin, sheep hoof 50
Gram.
Formula 3：10 grams of dalbergia wood, 12 grams of rhizoma nelumbinis, 7 grams of carbonized hair, 7 grams of the Fructus Sophorae, 5 grams of baked ginger, 7 grams of hedgehog skin, 50 grams of sheep hoof.
Formula 4：10 grams of dalbergia wood, 12 grams of rhizoma nelumbinis, 8 grams of crinis trachycarpi, 7 grams of the Fructus Sophorae, 5 grams of baked ginger, 7 grams of hedgehog skin, 50 grams of sheep hoof.
Formula 5：10 grams of dalbergia wood, 12 grams of rhizoma nelumbinis, 8 grams of crinis trachycarpi, 7 grams of carbonized hair, 5 grams of baked ginger, 7 grams of hedgehog skin, sheep hoof 50
Gram.
Formula 6：10 grams of dalbergia wood, 12 grams of rhizoma nelumbinis, 8 grams of crinis trachycarpi, 7 grams of carbonized hair, 7 grams of the Fructus Sophorae, 7 grams of hedgehog skin, sheep hoof 50
Gram.
Formula 7：10 grams of dalbergia wood, 12 grams of rhizoma nelumbinis, 8 grams of crinis trachycarpi, 7 grams of carbonized hair, 7 grams of the Fructus Sophorae, 5 grams of baked ginger, 50 grams of sheep hoof.
Formula 8：10 grams of dalbergia wood, 12 grams of rhizoma nelumbinis, 8 grams of crinis trachycarpi, 7 grams of carbonized hair, 7 grams of the Fructus Sophorae, 5 grams of baked ginger, hedgehog skin 7
Gram.
Inventive formulation：10 grams of dalbergia wood, 12 grams of rhizoma nelumbinis, 8 grams of crinis trachycarpi, 7 grams of carbonized hair, 7 grams of the Fructus Sophorae, 5 grams of baked ginger, hedgehog
7 grams of skin, 50 grams of sheep hoof.
Control group 1：Use certain commercially available hemostasis baiyao
Control group 2：Without using any haemostatic medicament.
Experimental method：Healthy adult new zealand white rabbit 1100, body weight 2.0-2.5kg, male and female dual-purpose.It is new by 1100
Western blue White Rabbit is randomly divided into 11 groups, every group 100, corresponds to above-mentioned formula 1- formulas 8, inventive formulation, the and of control group 1 respectively
Control group 2.Animal adaptability is tested after one week, and it is about 2cm, depth 0.5cm to be made long on White Rabbit hind leg with scalpel
Wound, cause Hemorrhage Model, entered immediately after using above-mentioned formula 1- formulas 8, inventive formulation, control group 1 and control group 2
Row administration, covers bleeding part using medicine and is stopped blooding, and starts timing, observes bleeding part every 30s, loses to 5s and ooze
Stop timing during blood, both obtain the bleeding time.
Experimental result is as follows：
| White Rabbit quantity | Dosage | Bleeding time | Hemostatic efficiency | |
| Formula 1 | 100 | 10g | 5.39±0.25 | 92% |
| Formula 2 | 100 | 10g | 5.11±0.49 | 95% |
| Formula 3 | 100 | 10g | 4. 24±0.61 | 93% |
| Formula 4 | 100 | 10g | 4.97±0.13 | 94% |
| Formula 5 | 100 | 10g | 5.35±0.67 | 96% |
| Formula 6 | 100 | 10g | 4.59±0.82 | 94% |
| Formula 7 | 100 | 10g | 5.77±0.29 | 95% |
| Formula 8 | 100 | 10g | 6.14±0.44 | 91% |
| Inventive formulation | 100 | 10g | 3.52±0.35 | 100% |
| Control group 1 | 100 | 10g | 7.65±0.83 | 93% |
| Control group 2 | 100 | 10g | 10.46±0.75 | 42% |
Find out from experiment, when using inventive formulation, cure rate is up to 100%, and treatment time is significantly reduced, when any less
During one Chinese medicine material, especially when lacking the monarch drug in a prescription sheep hoof in the present invention, do not go out to reaching curative effect of the invention
The blood time is longer, and efficient relatively low.Obvious inventive formulation lacks can not reach good curative effect simply.
Illustrate beneficial effects of the present invention with reference to Clinical practice data：
Hemostasis and pain-relieving gel provided by the invention effective percentage after patient takes is specific as follows up to more than 98%：
The selection standard of case：
Patient for hospital where me clinic case, totally 273, -10 years old 1 years old age 134, -30 years old 10 years old 62,30
Year -50 years old 50, more than 50 years old 25.
Application method：Medicine is applied to wound, three times a day.
Criterion of therapeutical effect：
Curative effect judging standard：Effective, effective, invalid three classes are divided into according to the correlation circumstance of wound healing.
It is effective：After the present invention, symptom disappears, and thoroughly cures；
Effectively：After the present invention, symptom substantially mitigates, but is not wholly absent；
It is invalid：After the present invention, symptom does not disappear, preceding without any improvement with taking.
Therapeutic effect：In 273 patients, 258 patients are using hemostasis and pain-relieving in the present invention 5 minutes, using hindering after three days
Mouth healing completely.10 patients after five days wound be completely recovered, 5 patients after one week wound be completely recovered, effective percentage reaches
100%, healing time is greatly improved.
Model case：
1st, Zhang, male, 10 years old, because playing, imprudence was scratched finger using fruit knife, wound depth 2mm, long 1cm, is bled tight
Weight, after to our hospital, be applied to wound using the present invention, stop blooding after 2 minutes, and pain weakens, and prevents infection from using bandage
Wrapping, second day wound closure, no longer bleeding, wound closure incrustation in the 3rd day.
2nd, Wu, women, 52 years old, palm is punctured accidentally using scissors, has hemostasis and pain-relieving gel of the present invention at home,
Wound is applied to immediately, is stopped blooding after 3 minutes, and pain weakens, daily to smear three times, is fully recovered after 7 days.
Preparation method in following examples is same as Example 1, repeats no more.
Embodiment 2：A kind of hemostasis and pain-relieving gel, it is characterised in that：It is formulated by the raw material of following portions by weight：
5 grams of dalbergia wood, 8 grams of rhizoma nelumbinis, 3 grams of crinis trachycarpi, 3 grams of carbonized hair, 4 grams of the Fructus Sophorae, 2 grams of baked ginger, 4 grams of hedgehog skin, 20 grams of sheep hoof.
Embodiment 3：A kind of hemostasis and pain-relieving gel, it is characterised in that：It is formulated by the raw material of following portions by weight：
20 grams of dalbergia wood, 20 grams of rhizoma nelumbinis, 15 grams of crinis trachycarpi, 12 grams of carbonized hair, 10 grams of the Fructus Sophorae, 10 grams of baked ginger, 10 grams of hedgehog skin, sheep hoof 70
Gram.
Embodiment 4：A kind of hemostasis and pain-relieving gel, it is characterised in that：It is formulated by the raw material of following portions by weight：
20 grams of dalbergia wood, 8 grams of rhizoma nelumbinis, 3 grams of crinis trachycarpi, 3 grams of carbonized hair, 4 grams of the Fructus Sophorae, 2 grams of baked ginger, 4 grams of hedgehog skin, 20 grams of sheep hoof.
Embodiment 5：A kind of hemostasis and pain-relieving gel, it is characterised in that：It is formulated by the raw material of following portions by weight：
5 grams of dalbergia wood, 20 grams of rhizoma nelumbinis, 3 grams of crinis trachycarpi, 3 grams of carbonized hair, 4 grams of the Fructus Sophorae, 2 grams of baked ginger, 4 grams of hedgehog skin, 20 grams of sheep hoof.
Embodiment 6：A kind of hemostasis and pain-relieving gel, it is characterised in that：It is formulated by the raw material of following portions by weight：
5 grams of dalbergia wood, 8 grams of rhizoma nelumbinis, 15 grams of crinis trachycarpi, 3 grams of carbonized hair, 4 grams of the Fructus Sophorae, 2 grams of baked ginger, 4 grams of hedgehog skin, 20 grams of sheep hoof.
Embodiment 7：A kind of hemostasis and pain-relieving gel, it is characterised in that：It is formulated by the raw material of following portions by weight：
5 grams of dalbergia wood, 8 grams of rhizoma nelumbinis, 3 grams of crinis trachycarpi, 12 grams of carbonized hair, 10 grams of the Fructus Sophorae, 2 grams of baked ginger, 4 grams of hedgehog skin, 20 grams of sheep hoof.
Embodiment 8：A kind of hemostasis and pain-relieving gel, it is characterised in that：It is formulated by the raw material of following portions by weight：
5 grams of dalbergia wood, 8 grams of rhizoma nelumbinis, 3 grams of crinis trachycarpi, 3 grams of carbonized hair, 4 grams of the Fructus Sophorae, 10 grams of baked ginger, 4 grams of hedgehog skin, 20 grams of sheep hoof.
Embodiment 9：A kind of hemostasis and pain-relieving gel, it is characterised in that：It is formulated by the raw material of following portions by weight：
5 grams of dalbergia wood, 8 grams of rhizoma nelumbinis, 3 grams of crinis trachycarpi, 3 grams of carbonized hair, 4 grams of the Fructus Sophorae, 2 grams of baked ginger, 10 grams of hedgehog skin, 70 grams of sheep hoof.
Embodiment 10：A kind of hemostasis and pain-relieving gel, it is characterised in that：It is by following portions by weight raw material prepare and
Into：20 grams of dalbergia wood, 20 grams of rhizoma nelumbinis, 3 grams of crinis trachycarpi, 3 grams of carbonized hair, 4 grams of the Fructus Sophorae, 2 grams of baked ginger, 4 grams of hedgehog skin, 20 grams of sheep hoof.
Embodiment 11：A kind of hemostasis and pain-relieving gel, it is characterised in that：It is by following portions by weight raw material prepare and
Into：5 grams of dalbergia wood, 20 grams of rhizoma nelumbinis, 15 grams of crinis trachycarpi, 3 grams of carbonized hair, 4 grams of the Fructus Sophorae, 2 grams of baked ginger, 4 grams of hedgehog skin, 20 grams of sheep hoof.
Embodiment 12：A kind of hemostasis and pain-relieving gel, it is characterised in that：It is by following portions by weight raw material prepare and
Into：5 grams of dalbergia wood, 8 grams of rhizoma nelumbinis, 15 grams of crinis trachycarpi, 12 grams of carbonized hair, 4 grams of the Fructus Sophorae, 2 grams of baked ginger, 4 grams of hedgehog skin, 20 grams of sheep hoof.
Embodiment 13：A kind of hemostasis and pain-relieving gel, it is characterised in that：It is by following portions by weight raw material prepare and
Into：5 grams of dalbergia wood, 8 grams of rhizoma nelumbinis, 3 grams of crinis trachycarpi, 12 grams of carbonized hair, 10 grams of the Fructus Sophorae, 10 grams of baked ginger, 10 grams of hedgehog skin, sheep hoof 20
Gram.
Embodiment 14：A kind of hemostasis and pain-relieving gel, it is characterised in that：It is by following portions by weight raw material prepare and
Into：5 grams of dalbergia wood, 20 grams of rhizoma nelumbinis, 15 grams of crinis trachycarpi, 12 grams of carbonized hair, 10 grams of the Fructus Sophorae, 10 grams of baked ginger, 10 grams of hedgehog skin, sheep hoof 70
Gram.
Embodiment 15：A kind of hemostasis and pain-relieving gel, it is characterised in that：It is by following portions by weight raw material prepare and
Into：20 grams of dalbergia wood, 8 grams of rhizoma nelumbinis, 15 grams of crinis trachycarpi, 12 grams of carbonized hair, 10 grams of the Fructus Sophorae, 10 grams of baked ginger, 10 grams of hedgehog skin, sheep hoof 70
Gram.
Embodiment 16：A kind of hemostasis and pain-relieving gel, it is characterised in that：It is by following portions by weight raw material prepare and
Into：20 grams of dalbergia wood, 20 grams of rhizoma nelumbinis, 3 grams of crinis trachycarpi, 12 grams of carbonized hair, 10 grams of the Fructus Sophorae, 10 grams of baked ginger, 10 grams of hedgehog skin, sheep hoof 70
Gram.
Embodiment 17：A kind of hemostasis and pain-relieving gel, it is characterised in that：It is by following portions by weight raw material prepare and
Into：20 grams of dalbergia wood, 20 grams of rhizoma nelumbinis, 15 grams of crinis trachycarpi, 3 grams of carbonized hair, 10 grams of the Fructus Sophorae, 10 grams of baked ginger, 10 grams of hedgehog skin, sheep hoof 70
Gram.
Embodiment 18：A kind of hemostasis and pain-relieving gel, it is characterised in that：It is by following portions by weight raw material prepare and
Into：20 grams of dalbergia wood, 20 grams of rhizoma nelumbinis, 15 grams of crinis trachycarpi, 12 grams of carbonized hair, 4 grams of the Fructus Sophorae, 10 grams of baked ginger, 10 grams of hedgehog skin, sheep hoof 70
Gram.
Embodiment 19：A kind of hemostasis and pain-relieving gel, it is characterised in that：It is by following portions by weight raw material prepare and
Into：20 grams of dalbergia wood, 20 grams of rhizoma nelumbinis, 15 grams of crinis trachycarpi, 12 grams of carbonized hair, 10 grams of the Fructus Sophorae, 3 grams of baked ginger, 10 grams of hedgehog skin, sheep hoof 70
Gram.
Embodiment 20：A kind of hemostasis and pain-relieving gel, it is characterised in that：It is by following portions by weight raw material prepare and
Into：20 grams of dalbergia wood, 20 grams of rhizoma nelumbinis, 15 grams of crinis trachycarpi, 12 grams of carbonized hair, 10 grams of the Fructus Sophorae, 10 grams of baked ginger, 6 grams of hedgehog skin, sheep hoof 70
Gram.
Embodiment 21：A kind of hemostasis and pain-relieving gel, it is characterised in that：It is by following portions by weight raw material prepare and
Into：20 grams of dalbergia wood, 20 grams of rhizoma nelumbinis, 15 grams of crinis trachycarpi, 12 grams of carbonized hair, 10 grams of the Fructus Sophorae, 10 grams of baked ginger, 10 grams of hedgehog skin, sheep hoof
30 grams.
Embodiment 22：A kind of hemostasis and pain-relieving gel, it is characterised in that：It is by following portions by weight raw material prepare and
Into：5 grams of dalbergia wood, 8 grams of rhizoma nelumbinis, 15 grams of crinis trachycarpi, 12 grams of carbonized hair, 10 grams of the Fructus Sophorae, 10 grams of baked ginger, 10 grams of hedgehog skin, sheep hoof 70
Gram.
Embodiment 23：A kind of hemostasis and pain-relieving gel, it is characterised in that：It is by following portions by weight raw material prepare and
Into：20 grams of dalbergia wood, 8 grams of rhizoma nelumbinis, 3 grams of crinis trachycarpi, 12 grams of carbonized hair, 10 grams of the Fructus Sophorae, 10 grams of baked ginger, 10 grams of hedgehog skin, sheep hoof 70
Gram.
Embodiment 24：A kind of hemostasis and pain-relieving gel, it is characterised in that：It is by following portions by weight raw material prepare and
Into：20 grams of dalbergia wood, 20 grams of rhizoma nelumbinis, 3 grams of crinis trachycarpi, 3 grams of carbonized hair, 10 grams of the Fructus Sophorae, 10 grams of baked ginger, 10 grams of hedgehog skin, sheep hoof 70
Gram.
Claims (4)
- A kind of 1. hemostasis and pain-relieving gel, it is characterised in that：It is formulated by the raw material of following portions by weight：Dalbergia wood 5-20 Part, rhizoma nelumbinis 8-20 parts, crinis trachycarpi 3-15 parts, carbonized hair 3-12 parts, Fructus Sophorae 4-10 parts, baked ginger 2-10 parts, hedgehog skin 4-10 parts, sheep Hoof 20-70 parts.
- A kind of 2. hemostasis and pain-relieving gel, it is characterised in that：It is formulated by the raw material of following portions by weight：Dalbergia wood 9-15 Part, rhizoma nelumbinis 10-15 parts, crinis trachycarpi 5-10 parts, carbonized hair 5-9 parts, Fructus Sophorae 6-9 parts, baked ginger 3-9 parts, hedgehog skin 6-9 parts, sheep hoof 30-60 parts.
- A kind of 3. hemostasis and pain-relieving gel, it is characterised in that：It is formulated by the raw material of following portions by weight：10 parts of dalbergia wood, 12 parts of rhizoma nelumbinis, 8 parts of crinis trachycarpi, 7 parts of carbonized hair, 7 parts of the Fructus Sophorae, 5 parts of baked ginger, 7 parts of hedgehog skin, 50 parts of sheep hoof.
- A kind of 4. preparation method of hemostasis and pain-relieving gel, it is characterised in that：Its preparation method is as follows：Step 1）, 10 parts of dalbergia wood, 12 parts of rhizoma nelumbinis, 8 parts of crinis trachycarpi, 7 parts of carbonized hair, the Fructus Sophorae are taken according to the parts by weight of the raw material 7 parts, 5 parts of baked ginger, 7 parts of hedgehog skin, 50 parts of sheep hoof, after washing carry out moist heat sterilization 10min-20min, then dried in dryer Dry 10min-20min, drying temperature is 25 DEG C -35 DEG C, finally by the dalbergia wood of drying, rhizoma nelumbinis, crinis trachycarpi, carbonized hair, the Fructus Sophorae, big gun Ginger, hedgehog skin, sheep hoof are put into pulverizer, are ground into 50-100 mesh powders, and active compound powder is made, standby；Step 2）, take 300 parts of 10 parts of carragheen, 20 parts of glycerine, 12 parts of polyoxyethylene sorbitan monoleate and distilled water, by 10 parts of carragheen 5-10 minutes are soaked in 20 parts of glycerine, 300 parts of distilled water is then added, is heated to 80 DEG C -100 DEG C, heats while stirring, 30 DEG C -40 DEG C are subsequently cooled to, 12 parts of polyoxyethylene sorbitan monoleates is added, stirs, room temperature is cooled to and gel forming agent is made；Step 3）, by step 1）The active compound powder of acquisition and step 2）Obtained gel forming agent presses 1：0.05-1：0.1 ratio Mixing, and stir, you can obtain described hemostasis and pain-relieving gel.
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Application publication date: 20180327 |