CN107823079A - A kind of sea cucumber EGF composition skin-care cosmetics and preparation method thereof - Google Patents
A kind of sea cucumber EGF composition skin-care cosmetics and preparation method thereof Download PDFInfo
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- CN107823079A CN107823079A CN201711068461.2A CN201711068461A CN107823079A CN 107823079 A CN107823079 A CN 107823079A CN 201711068461 A CN201711068461 A CN 201711068461A CN 107823079 A CN107823079 A CN 107823079A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/98—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
- A61K8/987—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
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Abstract
The present invention relates to a kind of sea cucumber EGF composition skin-care cosmetics.In parts by weight, its raw material includes wild 0.07 1.4 parts of stichopus japonicus extract solution, 0.03 0.6 parts of EGF stostes.Its raw material also includes 2~10 parts of natural extract.The present invention also provides a kind of preparation method of sea cucumber EGF composition skin-care cosmetics.The present invention can supplement the EGF of needed by human body, promote the Proliferation, Differentiation of cell, and can enough supplements a variety of nutriments required for holothurian collagen and cell proliferation and differentiation simultaneously, plays a part of cooperateing with EGF, can effectively delay cell senescence to prevent the aging with delaying skin.
Description
Technical field
The present invention relates to a kind of sea cucumber EGF composition skin-care cosmetics and preparation method thereof, belong to skin protection cosmetics field.
Background technology
Today's society, as the improvement of people's living standards, people increasingly pay attention to the aging of skin, prevent and delay skin
Skin aging has turned into one of focus of cosmetic science man research.The aging of skin is a complicated process, and life hair
The natural law of exhibition process.People has arrived ageing phase, and skin fiber tissue is gradually degenerated atrophy, relaxation, sweat gland, sebaceous glands
Metabolic function fade, cause dry skin, relaxation, wrinkle occur first in face particularly canthus, forehead etc..
Its main cause is in human body caused by collagen and EGF loss.
Collagen is a kind of very important protein of human body, and it is collagen egg to have 1/3rd in human body protein
In vain, it is primarily present in connective tissue.It has very strong stretch capability, is ligament and the Main Ingredients and Appearance of tendon forceps, collagen
Or the main constituents of extracellular matrix.It makes skin keep elastic, and the aging of collagen, then skin is wrinkled
Line.Recombinant human epidermal growth factor (EGF) is a kind of natural extract matter in human body, small point be made up of 53 amino acid
Sub- polypeptide, the highest awards-Nobel Prize for winning human sciences in 1986.EGF has extensive biological effect, and it is maximum special
Point is the Proliferation, Differentiation that can promote cell, so as to replace aging and dead cell with the cell of new life.With the increasing at age
Long, collagen and EGF in human body can gradually be lost in.Women collagen and EGF at 25 years old have begun to aging, stream
Lose, content declines year by year, then enters within 30 years old the peak period being lost in, and at 40 years old, half when content was less than 18 years old, the elderly is on the face
The wrinkle of ditch ditch bank, exactly because collagen and EGF are lost in.The loss of collagen causes the collagen peptide bond for supporting skin
It is broken with elasticated net, its spiral net-shaped structure is destroyed immediately, and skin histology is oxidized, atrophy, is collapsed；EGF loss, cell
Vigor decline, power of regeneration weaken, make the sluggish metabolism of Skin Cell, dryings, wrinkle, loose nothing just occurs in skin
The aging phenomenons such as elasticity.
Sea cucumber, belong to Holothuroidea, be a kind of ocean echinoderm, there is the survival history of more than 600,000,000 years away from the present.Sea cucumber, it is
One of eight big treasure of the world.Sea cucumber contains abundant collagen, compared with the collagen of other classifications, not only collagen
Purity it is higher, it is more a variety of dilute rich in 18 kinds of amino acid, Sea Cucumber Glycosides and the sea cucumber polysaccharide not available for other collagens etc.
There is composition, these compositions are the nutriments needed for body cell multiplication differentiation.Therefore, holothurian collagen is otherwise known as collagen
Local tyrant's gold in albumen.
EGF promotes cell proliferation and differentiation, and sea cucumber does not have one kind at present rich in a variety of nutriments such as collagens
While needed by human body EGF can either be supplemented, a variety of battalion needed for and can supplement holothurian collagen and its offer cell differentiation
Form point, can effectively delay cell senescence to prevent the skin protection cosmetics with delay skin aging.
Therefore, it is necessary to propose effective technical scheme, solve the above problems.
The content of the invention
The present invention is directed to above-mentioned the deficiencies in the prior art, there is provided a kind of sea cucumber EGF composition skin-care cosmetics.Offer can
While enough supplementing needed by human body EGF, a variety of battalion needed for and can supplement holothurian collagen and its offer cell proliferation and differentiation
Material is supported, can effectively delay cell senescence so as to prevent and delay skin aging.
The technical scheme that the present invention solves above-mentioned technical problem is as follows：
A kind of sea cucumber EGF composition skin-care cosmetics, in parts by weight, its raw material include wild stichopus japonicus extract solution
0.07-1.4 parts, EGF stoste 0.03-0.6 parts.
Preferably, the wild stichopus japonicus extract solution and the weight ratio of EGF stostes are 7：3.
Preferably, in parts by weight, its raw material also includes 2~10 parts of natural extract.
Preferably, the natural extract be Gotu Kola P.E, oat kernel extract, aloe barbadensis Miller leaf extract,
One or more mixing in hamamelis extract.
Preferably, in terms of 100 parts by weight, its raw material includes wild stichopus japonicus extract solution 0.07-1.4 parts, EGF stostes
0.03-0.6 parts, 2~10 parts of natural extract, 0.01~20 part of natural oil lipid, 0.01~20 part of Synthetic Oil, polyalcohol 2
~10 parts, 0.01~5 part of thickener, 0.01~5 part of higher alcohol, 0.01~10 part of emulsifying agent, 0.5~5 part of functional additive,
0.1~0.5 part of preservative, 0.01~0.5 part of essence, deionized water surplus.
The present invention also provides a kind of preparation method of sea cucumber EGF composition skin-care cosmetics, and step is as follows：
S1, it is added to after being well mixed natural oil lipid, thickener, higher alcohol and emulsifying agent by proportioning in water-bath,
In 75 DEG C~85 DEG C agitating and heating 20min~30min, oil phase is obtained；Polyalcohol, natural extract and feature are added by proportioning
Add agent to mix, and add deionized water, in 45 DEG C~55 DEG C agitating and heating 20min~30min, obtain aqueous phase；
Deionized water is added in S2, the oil phase obtained to step S1, is heated while stirring, reduces temperature to 45 DEG C~55
DEG C, preservative is proportionally added into, and aqueous phase described in adding step S1 is stirred until homogeneous dissolving；Continue to reduce solution temperature to 30 DEG C
~40 DEG C, essence is proportionally added into, is stirred until homogeneous dissolving；Solution temperature is finally reduced to room temperature, is proportionally added into wild thorn
After ginseng extract solution, EGF stostes stir, with citric acid regulating solution pH value to 6.0~7.0, mixed liquor is obtained；
S3, the 100 DEG C of sterilization 15min~30min of mixed liquor for obtaining step S2, produce present invention EGF containing sea cucumber combinations
Thing skin protection cosmetics.
Beneficial effect：
The present invention can supplement the EGF of needed by human body, promote the Proliferation, Differentiation of cell, while and can enough supplements sea cucumber collagen
A variety of nutriments required for albumen and cell proliferation and differentiation, play a part of cooperateing with EGF, can effectively delay thin
Born of the same parents' aging is so as to preventing the aging with delaying skin：
(1) act on cell membrane, acted on by LCK in target cell (TPK), cross-film transmits signal, leads
Receptor Protein Tyrosine residue phosphorylation is caused, makes gene activation in target cell core, acts on the relevant enzyme of DNA replication dna and thin
Born of the same parents are rised in value relevant gene expression, are promoted the Proliferation, Differentiation of cell, are largely produced neonatal cell, maintain or change neonatal cell with
The proportionate relationship of decline cell；
(2) resisting causes the stimulation of intracellular DNA break, foeign element such as ultraviolet, medicine, hormone etc. for making a variation to be done
Disturb, suppress the improper apoptosis speed of cell, increase the antijamming capability of skin；
(3) go deep into skin basalis, accelerate basal layer cell Proliferation, Differentiation, accelerate the generation of neoblast, allow senile cell
Quick angling, come off, the collagenous fibres and elastomer for make to be broken, be denatured are repaired, and skin elasticity increases, and wrinkle is gradual
Calm down, disappear.
(4) by changing the ratio of new old cell in skin, skin average age is reduced, skin is in young shape all the time
State, while melanin and coloured corpuscle content in skin can be reduced, the color spot of face gradually desalinated, disappeared, promote extracellular
Hyaluronic acid, mucopolysaccharide etc. synthesize and secretion, maintains the moisture of intradermal, strengthens epidermis endocuticle water holding capacity,
Allow skin to moisten and distribute vigor, effectively prevent the aging with delaying skin.
Embodiment
The present invention relates to a kind of sea cucumber EGF composition skin-care cosmetics, it is former that its raw material includes wild stichopus japonicus extract solution, EGF
It is liquid, natural extract, natural oil lipid, Synthetic Oil, polyalcohol, thickener, higher alcohol, emulsifying agent, functional additive, anti-
Rotten agent, essence, deionized water.
The natural extract be Gotu Kola P.E, oat kernel extract, pot marigold extract, purslane extract,
Royal jelly extract, aloe barbadensis Miller leaf extract, hamamelis extract, Astragalus Root P.E, licorice, spiceleaf day
One or more mixing of Zhu Kui extracts etc.；Preferably Gotu Kola P.E, oat kernel extract, Aloe Barbadensis Miller extraction
One or more mixing in thing, hamamelis extract；
The natural oil lipid be olive oil, macadamia nut oil, jojoba seed oil, Corn Seeds oil, shea butter, grape-kernel oil,
One kind in camellia seed oil, wheat-germ oil, sweet almond oil, evening primrose oil, coconut oil, palm oil, avocado oil, fat of Oromaius norvaehollandeae etc. or
A variety of mixing；One kind or more preferably in olive oil, macadamia nut oil, jojoba seed oil, shea butter, grape-kernel oil, fat of Oromaius norvaehollandeae
Kind mixing；
The artificial oil lipid is palm acid ethyl capronate, dimethyl silicone polymer, Dormant oils, cetostearyl alcohol ethyl hexyl
Acid esters, glycerine three (ethylhexoate), pentaerythrite ethylhexoate, isostearic acid ethylhexoate, isopropyl myristate,
One or more mixing in isononyl isononanoate, isopropyl palmitate etc.；Preferably palm acid ethyl capronate, poly dimethyl
Siloxanes, cetostearyl alcohol ethylhexoate, glycerine three (ethylhexoate), one kind in pentaerythrite ethylhexoate or more
Kind mixing；
The polyalcohol is that the one or more of glycerine, propane diols, butanediol, pentanediol, hexylene glycol, pungent glycol etc. are mixed
Close；One or more mixing preferably in glycerine, propane diols, butanediol；
The thickener be carbomer, hydroxyethyl cellulose, hydroxypropyl cellulose, guar gum, algin, carragheen,
One or more mixing of Arabic gum, gellan gum, xanthans, natural plant starch, gelatin etc.；Preferably hydroxy ethyl fiber
One or more mixing in element, carbomer, xanthans；
The higher alcohol is laruyl alcohol, cetanol, stearyl alcohol, isooctadecanol, phytosterol, lanonol, cholesterol, octyl group
One or more mixing of dodecanol etc.；One or more preferably in cetanol, stearyl alcohol, octyldodecanol are mixed
Close；
The emulsifying agent is stearic acid, cetostearyl alcohol olive oleate, the smooth olive oleate of sorb, glycerol stearate
One or more mixing of ester, lauryl glucoside, C12-20 alkyl glucosides, triethanolamine etc.；Preferably cetostearyl alcohol
One or more mixing of olive oleate, triethanolamine, C12-20 alkyl glucosides；
The functional additive be allantoin, hyaluronic acid, trehalose, polyglutamic acid, niacinamide, adenosine, glycine betaine,
One or more mixing of dipotassium glycyrrhizinate, vitamin E；Preferably in polyglutamic acid, Sodium Hyaluronate, glycine betaine, vitamin E
One or more mixing；
The preservative is methyl p-hydroxybenzoate, propylparaben, Phenoxyethanol, imidazolidinyl urea, double
One or more mixing of (methylol) imidazolidinyl urea, methylisothiazolinone, iodine propilolic alcohol butyl mephenesin Carbamate etc.；It is preferred that
For one or more mixing of methyl p-hydroxybenzoate, propylparaben, Phenoxyethanol；
The essence is the essence for meeting cosmetics odor type, such as：Skin protection cosmetics essence, preferably Beige ＆ Rose are fragrant
One kind in essence, white tea essence, lavender oil, cream jasmin france.
The formulation of skin protection cosmetics of the present invention can be watery, elite, emulsion, paste, white shape, gel, spraying, facial mask liquid its
In one kind.
Embodiment 1
A kind of sea cucumber EGF composition skin-care cosmetics of the present embodiment, its preparation method, comprise the following steps：
(1) according to wild stichopus japonicus extract solution 0.175g, EGF stostes 0.075g of formula precise, glycerine 4.0g, propane diols
2.0g, hamamelis extract 2.0g, aloe barbadensis Miller leaf extract 2.0g, trehalose 0.5g, allantoin 0.1g, hyalomitome
Sour sodium 0.05g, Phenoxyethanol 0.5g, white tea essence 0.02g, it is standby；
(2) by glycerine, propane diols, hamamelis extract, aloe barbadensis Miller leaf extract, trehalose, allantoin, thoroughly
Bright matter acid sodium mixing, adding deionized water makes it well mixed, it is preferred that 30g deionized waters is added, in 45 DEG C of agitating and heatings
20min, obtain aqueous phase；
(3) 58.58g deionized waters are added in water-bath, the benzene oxygen that aqueous phase and step 1 described in addition step 2 weigh
Ethanol, it is stirred until homogeneous dissolving；Continue to reduce solution temperature to 35 DEG C, add the white tea essence that step 1 weighs, be stirred until homogeneous
Dissolving；Solution temperature is finally reduced to room temperature, after the sea cucumber EGF compositions that addition step 1 weighs stir, is adjusted with citric acid
Solution ph is saved to 6.5, obtains mixed liquor；
(4) 100 DEG C of sterilization 15min of mixed liquor for obtaining step 3, the skin protection cosmetics of the compositions of EGF containing sea cucumber is produced.
Embodiment 2
A kind of sea cucumber EGF composition skin-care cosmetics of the present embodiment, its preparation method, comprise the following steps：
(1) according to wild stichopus japonicus extract solution 1.4g, EGF stostes 0.6g of formula precise, glycerine 4g, propane diols 2g, fourth
Glycol 2g, xanthans 0.5g, oat kernel extract 2g, Gotu Kola P.E 2g, royal jelly extract 1g, polyglutamic acid 0.5g,
Allantoin 0.1g, Sodium Hyaluronate 0.2g, Phenoxyethanol 0.5g, cream jasmin france 0.02g, it is standby；
(2) glycerine, propane diols, butanediol, xanthans, oat kernel extract, Gotu Kola P.E, royal jelly are extracted
Thing, polyglutamic acid, allantoin, Sodium Hyaluronate and the mixing of 30g ionized waters, in 47 DEG C of agitating and heating 25min, obtain aqueous phase；
(3) 58.58g deionized waters are added in water-bath；The benzene oxygen that aqueous phase and step 1 described in adding step 2 weigh
Ethanol, it is stirred until homogeneous dissolving；Continue to reduce solution temperature to 30 DEG C, add the cream jasmin france that step 1 weighs, be stirred until homogeneous
Dissolving；Solution temperature is finally reduced to room temperature, after the sea cucumber EGF compositions that addition step 1 weighs stir, is adjusted with citric acid
Solution ph is saved to 6.7, obtains mixed liquor；
(4) 100 DEG C of sterilization 20min of mixed liquor for obtaining step 3, the skin protection cosmetics of the compositions of EGF containing sea cucumber is produced.
Embodiment 3
A kind of sea cucumber EGF composition skin-care cosmetics of the present embodiment, its preparation method, comprise the following steps：
(1) according to wild stichopus japonicus extract solution 0.7g, EGF stostes 0.3g of formula precise, olive oil 1g, macadamia nut oil 1g,
Jojoba seed oil 2g, dimethyl silicone polymer 1.5g, cetanol ethylhexoate 1.5g, palm acid ethyl capronate 2g, glycerine
5g, propane diols 2g, hydroxyethyl cellulose 0.1g, xanthans 0.1g, octyldodecanol 0.8g, cetanol 1g, cetostearyl alcohol
The smooth olive oleate 0.5g of olive oleate 1g, sorb, licorice 2g, purslane extract 2g, Aloe Barbadensis Miller carry
Take thing 2g, Astragalus Root P.E 2g, glycine betaine 1.5g, allantoin 0.1g, Sodium Hyaluronate 0.1g, methyl p-hydroxybenzoate
0.2g, propylparaben 0.3g, Beige ＆ Rose essence 0.2g, it is standby.
(2) olive oil, macadamia nut oil, jojoba seed oil, dimethyl silicone polymer, the cetanol ethyl hexyl weighed step 1
Acid esters, palm acid ethyl capronate, octyldodecanol, cetanol, cetostearyl alcohol olive oleate and the smooth olive oil of sorb
It is added to after acid esters is well mixed in water-bath, in 80 DEG C of agitating and heating 25min, obtains oil phase；By glycerine, propane diols, hydroxyl second
Base cellulose, xanthans, licorice, purslane extract, aloe barbadensis Miller leaf extract, Astragalus Root P.E, glycine betaine,
Allantoin, Sodium Hyaluronate and the mixing of 30g deionized waters, in 50 DEG C of agitating and heating 30min, obtain aqueous phase；
(3) 58.58g deionized waters are added in water-bath, it is stirring while adding；Mixed solution temperature is reduced to 50
DEG C, the methyl p-hydroxybenzoate and propylparaben that aqueous phase and step 1 described in addition step 2 weigh, stir to equal
Even dissolving；Continue to reduce solution temperature to 31 DEG C, add the Beige ＆ Rose essence that step 1 weighs, be stirred until homogeneous dissolving；Most
Solution temperature is reduced afterwards to room temperature, after the sea cucumber EGF compositions that addition step 1 weighs stir, uses citric acid regulating solution
PH value obtains mixed liquor to 6.4；
(4) 100 DEG C of sterilization 25min of mixed liquor for obtaining step 3, the skin protection cosmetics of the compositions of EGF containing sea cucumber is produced.
Embodiment 4
A kind of sea cucumber EGF composition skin-care cosmetics of the present embodiment, its preparation method, comprise the following steps：
(1) according to wild stichopus japonicus extract solution 1.05g, EGF stostes 0.45g of formula precise, olive oil 1.5g, fat of Oromaius norvaehollandeae
2g, grape-kernel oil 2g, shea butter 3g, dimethyl silicone polymer 2g, pentaerythrite ethylhexoate 1.5g, palm acid ethyl oneself
Acid esters 3g, glycerine three (ethylhexoate) 1.5g, isopropyl myristate 1g, glycerine 4g, propane diols 4g, butanediol 2g, card ripple
Nurse 0.15g, xanthans 0.1g, stearyl alcohol 0.5g, cetanol 1.5g, triethanolamine 0.15g, C12-20 alkyl glucoside 2.5g,
Gotu Kola P.E 2g, hamamelis extract 2g, oat kernel extract 2g, Pelargonium roseum extract 2g, niacinamide 2g,
Sodium Hyaluronate 0.15g, polyglutamic acid 0.5g, methyl p-hydroxybenzoate 0.1g, 0.2 part of propylparaben, benzene oxygen
It is ethanol 0.2g, lavender fragrance 0.3g, standby.
(2) olive oil, fat of Oromaius norvaehollandeae, grape-kernel oil, shea butter, dimethyl silicone polymer, the Ji Wusi weighed step 1
Alcohol ethylhexoate, palm acid ethyl capronate, glycerine three (ethylhexoate), isopropyl myristate, stearyl alcohol, spermaceti
It is added in water-bath after alcohol, triethanolamine and C12-20 alkyl glucosides are well mixed, in 78 DEG C of agitating and heating 30min, obtains
To oil phase；Glycerine, propane diols, butanediol, carbomer, xanthans and 30g deionized waters are mixed, in 45 DEG C of agitating and heatings
28min, obtain aqueous phase；
(3) 58.58g deionized waters are added in water-bath, it is stirring while adding；Mixed solution temperature is reduced to 45
DEG C, Phenoxyethanol, methyl p-hydroxybenzoate and the propylparaben that aqueous phase and step 1 described in addition step 2 weigh,
It is stirred until homogeneous dissolving；Continue to reduce solution temperature to 35 DEG C, add the lavender fragrance that step 1 weighs, be stirred until homogeneous molten
Solution；Solution temperature is finally reduced to room temperature, after the sea cucumber EGF compositions that addition step 1 weighs stir, is adjusted with citric acid
Solution ph obtains mixed liquor to 6.8；
(4) 100 DEG C of sterilization 30min of mixed liquor for obtaining step 3, the skin protection cosmetics of the compositions of EGF containing sea cucumber is produced.
The present invention can be summarized with others without prejudice to the concrete form of the spirit or essential characteristics of the present invention.Therefore, nothing
By from the point of view of which point, the embodiment above of the invention can only all be considered the description of the invention and can not limit this hair
Bright, claims indicate the scope of the present invention, and above-mentioned explanation does not point out the scope of the present invention, therefore, with this
Any change in claims of invention suitable implication and scope, all it is considered as the claim for being included in the present invention
In the range of book.
Claims (6)
1. a kind of sea cucumber EGF composition skin-care cosmetics, it is characterised in that in parts by weight, its raw material includes wild stichopus japonicus
Extract solution 0.07-1.4 parts, EGF stoste 0.03-0.6 parts.
2. sea cucumber EGF composition skin-care cosmetics as claimed in claim 1, it is characterised in that the wild stichopus japonicus extract solution
Weight ratio with EGF stostes is 7：3.
3. sea cucumber EGF composition skin-care cosmetics as claimed in claim 1 or 2, it is characterised in that in parts by weight, its
Raw material also includes 2~10 parts of natural extract.
4. sea cucumber EGF composition skin-care cosmetics as claimed in claim 3, it is characterised in that the natural extract is product
The one or more avenged in careless extract, oat kernel extract, aloe barbadensis Miller leaf extract, hamamelis extract are mixed
Close.
5. sea cucumber EGF composition skin-care cosmetics as claimed in claim 4, it is characterised in that in terms of 100 parts by weight, its
Raw material includes wild stichopus japonicus extract solution 0.07-1.4 parts, EGF stoste 0.03-0.6 parts, 2~10 parts of natural extract, natural oil
0.01~20 part of class, 0.01~20 part of Synthetic Oil, 2~10 parts of polyalcohol, 0.01~5 part of thickener, higher alcohol 0.01~5
Part, 0.01~10 part of emulsifying agent, 0.5~5 part of functional additive, 0.1~0.5 part of preservative, 0.01~0.5 part of essence, go
Ion water surplus.
A kind of 6. preparation method of sea cucumber EGF composition skin-care cosmetics as claimed in claim 5, it is characterised in that step
It is as follows：
S1, it is added to after being well mixed natural oil lipid, thickener, higher alcohol and emulsifying agent by proportioning in water-bath, 75
DEG C~85 DEG C of agitating and heating 20min~30min, obtain oil phase；By proportioning by polyalcohol, natural extract and functional additive
Mixing, and deionized water is added, in 45 DEG C~55 DEG C agitating and heating 20min~30min, obtain aqueous phase；
Deionized water is added in S2, the oil phase obtained to step S1, is heated while stirring, temperature is reduced to 45 DEG C~55 DEG C, presses
Ratio adds preservative, and aqueous phase described in adding step S1 is stirred until homogeneous dissolving；Continue to reduce solution temperature to 30 DEG C~40
DEG C, essence is proportionally added into, is stirred until homogeneous dissolving；Solution temperature is finally reduced to room temperature, wild stichopus japonicus is proportionally added into and carries
After taking liquid, EGF stostes to stir, with citric acid regulating solution pH value to 6.0~7.0, mixed liquor is obtained；
S3, the 100 DEG C of sterilization 15min~30min of mixed liquor for obtaining step S2, produce present invention EGF containing sea cucumber compositions shield
Skin cosmetics.
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| CN109481333A (en) * | 2018-12-13 | 2019-03-19 | 昆明白鸥微藻技术有限公司 | A kind of astaxanthin EGF stoste and preparation method thereof |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN109091427A (en) * | 2018-08-31 | 2018-12-28 | 广州东智盟化妆品有限公司 | A kind of deep layer whitening sun protection restoration, skin essence lotion and preparation method thereof |
| CN109481333A (en) * | 2018-12-13 | 2019-03-19 | 昆明白鸥微藻技术有限公司 | A kind of astaxanthin EGF stoste and preparation method thereof |
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Application publication date: 20180323 |