CN107823005A - A kind of skin care compositions of anti-acne reparation containing Folium Rhododendri Simsii extract and application - Google Patents
A kind of skin care compositions of anti-acne reparation containing Folium Rhododendri Simsii extract and application Download PDFInfo
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- CN107823005A CN107823005A CN201711315614.9A CN201711315614A CN107823005A CN 107823005 A CN107823005 A CN 107823005A CN 201711315614 A CN201711315614 A CN 201711315614A CN 107823005 A CN107823005 A CN 107823005A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/362—Polycarboxylic acids
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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Abstract
The invention discloses a kind of skin care compositions of anti-acne reparation containing Folium Rhododendri Simsii extract and application, belongs to technical field of skin care, and the composition of anti-acne reparation includes the component of following mass fraction：6~11 parts of 11~17 parts of azalaic acid, 10~16 parts of white pond lily extract and Bai Yela oil of Flos Chrysanthemi；The weight/mass percentage composition of skin care compositions is 5.5% in skin care item.The present invention skin care compositions and skin care item not but not damage skin, and anti-acne repair the effect of it is good.
Description
Technical field
The invention belongs to technical field of skin care, more particularly to a kind of skin care group of the anti-acne reparation containing Folium Rhododendri Simsii extract
Compound and application.
Background technology
The whelk of face is formed by following several factors：1) smegma is vigorous, sebum accumulation；2) on follicular orifice
Skin hyperplasia keratinization, hair follicle block；3) propionibacterium acnes amount reproduction, hair follicle inflammatory reaction.However, existing anti-acne
The synthesis chemical reagent added in remediation composition and skin care item is excessive, easily damages skin；Secondly, the effect of anti-acne is repaired
Difference.
Therefore, it is necessary to prepare new composition and skin care item, its not but not damage skin, and anti-acne reparation
The effect of it is good.
The content of the invention
Present invention aims to overcome that the shortcomings of the prior art, and a kind of anti-acne containing Folium Rhododendri Simsii extract is provided and repaiied
Multiple skin care compositions and application, the skin care compositions and skin care item not but not damage skin, and anti-acne repair the effect of
It is good.
To achieve the above object, the technical scheme taken of the present invention is：A kind of skin care compositions of anti-acne reparation, it is included
The component of following mass fraction：11~17 parts of azalaic acid, 10~16 parts of white pond lily extract and Bai Yela oil of Flos Chrysanthemi 6~11
Part.
Azalaic acid is Folium Rhododendri Simsii extract, and azalaic acid can suppress, kill skin and intrafollicular bacterium, eliminate cause of disease
Body；The grease of skin hypersecretion can also be reduced.White pond lily extract includes flavones and polyphenol, can whitening and moisturizing.Bai Ye
Cured oil of Flos Chrysanthemi derives from Bai Yela chrysanthemums, and it has the effect of moisturizing and skin care are moistened.
The skin care compositions of the present invention includes azalaic acid (Folium Rhododendri Simsii extract), white pond lily extract and Bai Yela chrysanthemums
Oil, azalaic acid, white pond lily extract and Bai Yela oil of Flos Chrysanthemi can reduce the secretion of grease and resist in the range of certain proportion
Bacterium anti-inflammatory, can efficiently anti-acne reparation；And the skin care compositions is mostly natural materials, to skin zero damage.
As the improvement of above-mentioned technical proposal, skin care compositions includes the component of following mass fraction：Azalaic acid 14~
6~9 parts of 17 parts, 10~14 parts of white pond lily extract and Bai Yela oil of Flos Chrysanthemi.
As the improvement of above-mentioned technical proposal, the mass ratio of the azalaic acid and the white pond lily extract for 1.5~
1.7.When the mass ratio of azalaic acid and white lotus flower extract is 1.5~1.7, skin care compositions anti-acne can be further enhanced and repaiied
The effect of multiple.
As the further improvement of above-mentioned technical proposal, the mass ratio of the azalaic acid and the white pond lily extract is
1.6。
As the further improvement of above-mentioned technical proposal, the mass ratio of the azalaic acid and the white pond lily extract is
1.5。
As the further improvement of above-mentioned technical proposal, skin care compositions is made up of the component of following mass fraction：Du
Cuckoo spends 7 parts of 16 parts of acid, 10 parts of white pond lily extract and Bai Yela oil of Flos Chrysanthemi.
As the further improvement of above-mentioned technical proposal, skin care compositions is made up of the component of following mass fraction：Du
Cuckoo spends 8.2 parts of 16.5 parts of acid, 11 parts of white pond lily extract and Bai Yela oil of Flos Chrysanthemi.
In addition, the present invention also provides application of the described skin care compositions in skin care item.
In addition, the present invention also provides a kind of skin care item for including described skin care compositions.
As the improvement of above-mentioned technical proposal, the skin care item are made up of the component of lower weight/mass percentage composition：Skincare composition
Thing 5.5%, NMF 11.6% and emulsifying agent 13%, surplus are deionized water.
The beneficial effects of the present invention are：The present invention provides a kind of skincare composition of the anti-acne reparation containing Folium Rhododendri Simsii extract
Thing and application, the matter of azalaic acid, white pond lily extract and Bai Yela oil of Flos Chrysanthemi in skin care compositions and skin care item of the invention
Amount efficiently can carry out anti-acne reparation in the range of certain proportion to face；And it is mostly in the skin care compositions and skin care item
Natural materials, to skin zero damage.
Embodiment
For the object, technical solutions and advantages of the present invention are better described, below in conjunction with specific embodiment and subordinate list pair
The present invention is described further.
Embodiment 1
A kind of skin care compositions of anti-acne reparation, it is made up of the component of following mass fraction：11 parts of azalaic acid, sleep in vain
6 parts of 14 parts of lotus extract and Bai Yela oil of Flos Chrysanthemi.
The present embodiment also provides a kind of skin care item, and it is made up of the component of following weight/mass percentage composition：Skin care compositions
5.5%th, NMF (butantriol and glycerine) 11.6% and emulsifying agent (sorbierite olive grease) 13%, surplus is deionized water.
Embodiment 2
A kind of skin care compositions of anti-acne reparation, it is made up of the component of following mass fraction：17 parts of azalaic acid, sleep in vain
8.6 parts of 16 parts of lotus extract and Bai Yela oil of Flos Chrysanthemi.
The present embodiment also provides a kind of skin care item, and it is made up of the component of following weight/mass percentage composition：Skin care compositions
5.5%th, NMF (butantriol and glycerine) 11.6% and emulsifying agent (sorbierite olive grease) 13%, surplus is deionized water.
Embodiment 3
A kind of skin care compositions of anti-acne reparation, it is made up of the component of following mass fraction：14 parts of azalaic acid, sleep in vain
11 parts of 10 parts of lotus extract and Bai Yela oil of Flos Chrysanthemi.
The present embodiment also provides a kind of skin care item, and it is made up of the component of following weight/mass percentage composition：Skin care compositions
5.5%th, NMF (butantriol and glycerine) 11.6% and emulsifying agent (sorbierite olive grease) 13%, surplus is deionized water.
Embodiment 4
A kind of skin care compositions of anti-acne reparation, it is made up of the component of following mass fraction：16 parts of azalaic acid, sleep in vain
7 parts of 10 parts of lotus extract and Bai Yela oil of Flos Chrysanthemi.
The present embodiment also provides a kind of skin care item, and it is made up of the component of following weight/mass percentage composition：Skin care compositions
5.5%th, NMF (butantriol and glycerine) 11.6% and emulsifying agent (sorbierite olive grease) 13%, surplus is deionized water.
Embodiment 5
A kind of skin care compositions of anti-acne reparation, it is made up of the component of following mass fraction：It is 16.5 parts of azalaic acid, white
8.2 parts of 11 parts of water lily extract and Bai Yela oil of Flos Chrysanthemi.
The present embodiment also provides a kind of skin care item, and it is made up of the component of following weight/mass percentage composition：Skin care compositions
5.5%th, NMF (butantriol and glycerine) 11.6% and emulsifying agent (sorbierite olive grease) 13%, surplus is deionized water.
Embodiment 6
A kind of skin care compositions of anti-acne reparation, it is made up of the component of following mass fraction：17 parts of azalaic acid, sleep in vain
6 parts of 10 parts of lotus extract and Bai Yela oil of Flos Chrysanthemi.
The present embodiment also provides a kind of skin care item, and it is made up of the component of following weight/mass percentage composition：Skin care compositions
5.5%th, NMF (butantriol and glycerine) 11.6% and emulsifying agent (sorbierite olive grease) 13%, surplus is deionized water.
Comparative example 1
A kind of skin care compositions of anti-acne reparation, it is made up of the component of following mass fraction：17 parts of azalaic acid and white
10 parts of water lily extract.
The present embodiment also provides a kind of skin care item, and it is made up of the component of following weight/mass percentage composition：Skin care compositions
5.5%th, NMF (butantriol and glycerine) 11.6% and emulsifying agent (sorbierite olive grease) 13%, surplus is deionized water.
Comparative example 2
A kind of skin care compositions of anti-acne reparation, it is made up of the component of following mass fraction：25 parts of azalaic acid, sleep in vain
4 parts of 10 parts of lotus extract and Bai Yela oil of Flos Chrysanthemi.
The present embodiment also provides a kind of skin care item, and it is made up of the component of following weight/mass percentage composition：Skin care compositions
5.5%th, NMF (butantriol and glycerine) 11.6% and emulsifying agent (sorbierite olive grease) 13%, surplus is deionized water.
Effect example 1
1) propionibacterium acnes Anaerobic culturel 24h in dextrose broth is taken, afterwards with 0.03mol/L PBSs,
Bacteria concentration is made as 106Cfu/mL bacteria suspension；Take skin care item 1g to add in above-mentioned 0.1mL bacteria suspensions uniformly to mix, after 20min
9mL 0.03mol/L PBS are added, are fully mixed；After appropriate dilution, wherein 3 dilution factors are taken, takes 1mL to be placed in two respectively and puts down
In row culture dish, nutrient solution, Hybrid NC machine tool are added.Bacterium colony is recorded after 48h, is averaged, while sets blank control.Inhibiting rate
Calculation formula be：Clump count × 100% of (clump counts of clump count-skin care item of blank control)/blank control.
It is randomly divided into 5 groups：A11 groups use the skin care item of embodiment 1, and B11 groups use the skin care item of embodiment 2, and C11 groups make
With the skin care item of embodiment 3, D11 groups use the skin care item of comparative example 1, and E11 groups use the skin care item of comparative example 2, inhibiting rate
Measurement result is as shown in table 1.
Table 1
| Group | A11 groups | B11 groups | C11 groups | D11 groups | E11 groups |
| Inhibiting rate/% | 42.6 | 41.3 | 40.0 | 25.1 | 28.7 |
As shown in table 1, the propionibacterium acnes inhibiting rate of A11, B11 and C11 group is more than the acne propionic acid of D11 and E11 groups
Bacillus inhibiting rate；As can be seen here, when azalaic acid in skin care compositions mass fraction be 11~17 parts, white pond lily extract
Mass fraction is 10~16 parts, when the mass fraction of Bai Yela oil of Flos Chrysanthemi is 6~11 parts, the acne of skin care compositions and skin care item
It is preferable that Propionibacterium suppresses effect.
2) choosing face has the volunteer of whelk, and week for 7 weeks smears shin moisturizer to face；Surveyed with skin oil and fat tester
Surely smear shin moisturizer before and after face skin oil and fat content, calculate facial skin grease reduced rate.
250 volunteers are taken, are randomly divided into 5 groups：A12 groups smear the skin care item of embodiment 1, and B12 groups smear embodiment 2
Skin care item, C12 groups smear the skin care item of embodiment 3, and D12 groups smear the skin care item of embodiment 4, and E12 groups smear the shield of embodiment 5
Skin product, the measurement result of skin oil and fat reduced rate are as shown in table 2.
Table 2
| Group | A12 groups | B12 groups | C12 groups | D12 groups | E12 groups |
| Skin oil and fat reduced rate/% | 20.9 | 19.8 | 22.4 | 9.5 | 13.4 |
As shown in table 2, the skin oil and fat reduced rate of A12, B12 and C12 group is more than the skin oil and fat reduction of D12 and E12 groups
Rate；As can be seen here, when azalaic acid in skin care compositions mass fraction be 11~17 parts, the mass fraction of white pond lily extract
For 10~16 parts, when the mass fraction of Bai Yela oil of Flos Chrysanthemi is 6~11 parts, skin care compositions and skin care item can preferably reduce skin
The secretory volume of skin grease.
With reference to Tables 1 and 2, it is seen that when the mass fraction of azalaic acid in skin care compositions is 11~17 parts, white pond lily carries
The mass fraction for taking thing is 10~16 parts, when the mass fraction of Bai Yela oil of Flos Chrysanthemi is 6~11 parts, skin care compositions and skin care item
Can preferably anti-acne reparation.
Effect example 2
1) effect example 1 is referred to, is randomly divided into 6 groups：A21 groups use the skin care item of embodiment 1, and B21 groups use embodiment 2
Skin care item, C21 groups use the skin care item of embodiment 3, and D21 groups use the skin care item of embodiment 4, and E21 groups use the shield of embodiment 5
Skin product, F21 groups use the skin care item of embodiment 6, and the measurement result of inhibiting rate is as shown in table 3.
Table 3
| Group | A21 groups | B21 groups | C21 groups | D21 groups | E21 groups | F21 groups |
| Inhibiting rate/% | 42.6 | 41.3 | 40.0 | 60.9 | 62.1 | 58.3 |
As shown in table 3, the propionibacterium acnes inhibiting rate of A21, B21 and C21 group is less than the acne of D21, E21 and F21 group
Propionibacterium inhibiting rate；As can be seen here, when the mass fraction of azalaic acid in skin care compositions is 14~17 parts, white pond lily extracts
The mass fraction of thing is 10~14 parts, and the mass fraction of Bai Yela oil of Flos Chrysanthemi is 6~9 parts, and azalaic acid extracts with white pond lily
When the mass ratio of thing is 1.5~1.7, azalaic acid can further cooperate with suppression propionibacterium acnes with white pond lily extract, shield
It is more preferable that the propionibacterium acnes of skin composition and skin care item suppresses effect.
2) effect example 1 is referred to, 300 volunteers is taken, is randomly divided into 6 groups：A22 groups smear the skin care item of embodiment 1, B22
Group smears the skin care item of embodiment 2, and C22 groups smear the skin care item of embodiment 3, and D22 groups smear the skin care item of embodiment 4, E22 groups
The skin care item of embodiment 5 are smeared, F22 groups smear the skin care item of embodiment 6, the measurement result such as institute of table 4 of skin oil and fat reduced rate
Show.
Table 4
As shown in table 4, the skin oil and fat reduced rate of A22, B22 and C22 group is less than the skin oil and fat of D22, E22 and F22 group
Reduced rate；As can be seen here, when azalaic acid in skin care compositions mass fraction be 14~17 parts, the quality of white pond lily extract
Number is 10~14 parts, and the mass fraction of Bai Yela oil of Flos Chrysanthemi is 6~9 parts, the mass ratio of azalaic acid and white pond lily extract
For 1.5~1.7 when, azalaic acid and white pond lily extract can further cooperate with the secretory volume for suppressing to reduce skin oil and fat, skin care
Composition and skin care item can more attentively reduce the secretory volume of skin oil and fat.
Consolidated statement 3 and table 4, it is seen that when the mass fraction of azalaic acid in skin care compositions is 14~17 parts, white pond lily carries
The mass fraction for taking thing is 10~14 parts, and the mass fraction of Bai Yela oil of Flos Chrysanthemi is 6~9 parts, and azalaic acid extracts with white pond lily
When the mass ratio of thing is 1.5~1.7, skin care compositions and the preferably anti-acne reparation of skin care liquid energy.
Effect example 3
Choosing 250 faces has the volunteer of whelk, is randomly divided into 5 groups：A3 groups smear the skin care item of comparative example 1, B3
Group smears the skin care item of embodiment 1, and C3 groups smear the skin care item of embodiment 4, the skin care item of D3 groups embodiment 5, and E3 groups are smeared real
Apply the skin care item of example 6；The face of volunteer is early daily, evening respectively smears 1 skin care item, continuous to smear 5 weeks, during which without using other
Skin care item；After 5 weeks, survey volunteer's using effect, efficacy result is shown in Table 5；Efficacy assessment standard is as follows：It is effective：Face
Whelk is largely reduced, and skin becomes smoother；Effectively：Face's whelk has been reduced, and skin becomes somewhat smooth；Nothing
Effect：Face's whelk and skin change unobvious.
Table 5
| Group | Effective/people | Effectively/people | Invalid/people |
| A3 groups | 0 | 10 | 40 |
| B3 groups | 3 | 30 | 17 |
| C3 groups | 30 | 20 | 0 |
| D3 groups | 35 | 15 | 0 |
| E3 groups | 25 | 25 | 0 |
As shown in table 5, after volunteer is smeared using the skin care item group of the application, whelk is largely reduced, and skin becomes to compare
It is more smooth；Especially when azalaic acid in skin care compositions mass fraction be 14~17 parts, the mass fraction of white pond lily extract
For 10~14 parts, the mass fraction of Bai Yela oil of Flos Chrysanthemi is 6~9 parts, and the mass ratio of azalaic acid and white pond lily extract is 1.5
When~1.7, composition and skin care item can preferably anti-acne reparations.
Finally, it should be noted that above example to illustrate technical scheme rather than to the present invention protect
The limitation of scope, although being explained in detail with reference to preferred embodiment to the present invention, one of ordinary skill in the art should manage
Solution, technical scheme can be modified or replaced on an equal basis, without departing from technical solution of the present invention essence and
Scope.
Claims (10)
1. a kind of skin care compositions of anti-acne reparation, it is characterised in that include the component of following mass fraction：Azalaic acid 11~
6~11 parts of 17 parts, 10~16 parts of white pond lily extract and Bai Yela oil of Flos Chrysanthemi.
2. skin care compositions as claimed in claim 1, it is characterised in that include the component of following mass fraction：Azalaic acid
6~9 parts of 14~17 parts, 10~14 parts of white pond lily extract and Bai Yela oil of Flos Chrysanthemi.
3. skin care compositions as claimed in claim 1 or 2, it is characterised in that the azalaic acid extracts with the white pond lily
The mass ratio of thing is 1.5~1.7.
4. skin care compositions as claimed in claim 3, it is characterised in that the azalaic acid and the white pond lily extract
Mass ratio is 1.6.
5. skin care compositions as claimed in claim 3, it is characterised in that the azalaic acid and the white pond lily extract
Mass ratio is 1.5.
6. skin care compositions as claimed in claim 4, it is characterised in that be made up of the component of following mass fraction：Azalea
7 parts of 16 parts of acid, 10 parts of white pond lily extract and Bai Yela oil of Flos Chrysanthemi.
7. skin care compositions as claimed in claim 5, it is characterised in that be made up of the component of following mass fraction：Azalea
8.2 parts of 16.5 parts of acid, 11 parts of white pond lily extract and Bai Yela oil of Flos Chrysanthemi.
8. application of the skin care compositions as described in any one of claim 1~7 in skin care item.
A kind of 9. skin care item for including the skin care compositions as described in power requires 1~6 any one.
10. skin care item as claimed in claim 9, it is characterised in that be made up of the component of following weight/mass percentage composition：Skin care group
Compound 5.5%, NMF 11.6% and emulsifying agent 13%, surplus are deionized water.
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| CN201711315614.9A CN107823005A (en) | 2017-12-07 | 2017-12-07 | A kind of skin care compositions of anti-acne reparation containing Folium Rhododendri Simsii extract and application |
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| CN201711315614.9A CN107823005A (en) | 2017-12-07 | 2017-12-07 | A kind of skin care compositions of anti-acne reparation containing Folium Rhododendri Simsii extract and application |
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| CN108670926A (en) * | 2018-07-09 | 2018-10-19 | 广州赛莱拉干细胞科技股份有限公司 | Moisturizing composition and skin care product containing same |
| CN113318053A (en) * | 2021-07-07 | 2021-08-31 | 广东伊留美化妆品有限公司 | Preparation method and application of whitening and freckle-removing composition |
| US11786451B2 (en) | 2019-06-28 | 2023-10-17 | The Procter & Gamble Company | Skin care composition |
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| CN101690704A (en) * | 2009-08-21 | 2010-04-07 | 珈侬生化科技(中国)有限公司 | Rhododendron active extract preparation and whitening anti-aging active cosmetic |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN108670926A (en) * | 2018-07-09 | 2018-10-19 | 广州赛莱拉干细胞科技股份有限公司 | Moisturizing composition and skin care product containing same |
| US11786451B2 (en) | 2019-06-28 | 2023-10-17 | The Procter & Gamble Company | Skin care composition |
| CN113318053A (en) * | 2021-07-07 | 2021-08-31 | 广东伊留美化妆品有限公司 | Preparation method and application of whitening and freckle-removing composition |
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