CN105796404A - Anticorrosion composition and application to daily chemical products - Google Patents
Anticorrosion composition and application to daily chemical products Download PDFInfo
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- CN105796404A CN105796404A CN201610145851.4A CN201610145851A CN105796404A CN 105796404 A CN105796404 A CN 105796404A CN 201610145851 A CN201610145851 A CN 201610145851A CN 105796404 A CN105796404 A CN 105796404A
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- extract
- radix scutellariae
- pericarpium granati
- anticorrosive composite
- alkali
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/368—Carboxylic acids; Salts or anhydrides thereof with carboxyl groups directly bound to carbon atoms of aromatic rings
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/41—Amines
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/10—General cosmetic use
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/52—Stabilizers
- A61K2800/524—Preservatives
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Abstract
The invention discloses an anticorrosion composition.The anticorrosion composition is characterized by comprising, by weight, 0.1%-30% of gluconolactone (and) sodium benzoate, 0.1%-10% of alkali, 10%-60% of scutellaria baicalensis extract and 10%-50% of pomegranate peel extract.The anticorrosion composition has the good anticorrosion effect and is safe and free of irritation, and the defect that as present anticorrosion agents for daily chemical products are large in irritation, the harm to the skin of the human body is large is overcome.
Description
Technical field
The present invention relates to a kind of anticorrosive composite, said composition can be applicable in household chemicals, reaches anticorrosion purpose, belongs to
In filed of daily-use chemical industry.
Background technology
Containing abundant nutrient pledge in household chemicals, it is particularly suitable for growth of microorganism, so in household chemicals
Need to add preservative.The purpose adding preservative at household chemicals is contemplated to suppress growth of microorganism and generation, it is to avoid
Household chemicals produces denaturalization phenomenon and maintains freshness and lasting effect.
At present, conventional in household chemicals preservative have p-Hydroxybenzoate, imidazolidinyl urea, in uride, different
Thiazolinone, phenyl phenol etc..These preservative have certain injury to human body skin, easily cause skin allergy.
Along with the progress of science and technology, growth in the living standard.Consumer increasingly payes attention to skin care, increasingly pays close attention to daily
The safety of chemicals, pursues natural skin care.So, chemical preservative safety is thrown doubt upon by consumer, increasingly pursues
Natural, healthy skin protection, promotes household chemicals industry to begin look for the alternative route of preservative.Research and use non-stimulated,
The compositions of the potent antiseptic effect that safety is high becomes the focus of household chemicals research.
Summary of the invention
It is an object of the invention to provide the compositions with preservative efficacy that a kind of zest is low, safety is high.
To achieve the object of the present invention, present invention employs following technical scheme:
A kind of anticorrosive composite, it is characterised in that be made up of the component of following percentage by weight: gluconolactone (and) benzoic acid
Sodium 0.1-30%, alkali 0.1-10%, Radix Scutellariae extract 10-60, Pericarpium Granati extract 10-50%.
Preferably, described a kind of anticorrosive composite, it is characterised in that be made up of the component of following percentage by weight: gluconic acid
Lactone (and) sodium benzoate 1-25%, alkali 0.2-8%, Radix Scutellariae extract 15-50%, Pericarpium Granati extract 15-45%.
Preferably, described a kind of anticorrosive composite, it is characterised in that be made up of the component of following percentage by weight: gluconic acid
Lactone (and) sodium benzoate 5-20%, alkali 0.2-6%, Radix Scutellariae extract 20-50%, Pericarpium Granati extract 15-40%.
Preferably, described a kind of anticorrosive composite, it is characterised in that comprise the component of following percentage by weight: in gluconic acid
Ester (and) sodium benzoate 5-20%, alkali 0.3-5%, Radix Scutellariae extract 20-45, Pericarpium Granati extract 20-45%.
Described Radix Scutellariae extract, Pericarpium Granati extract, its preparation method is: Radix Scutellariae, Pericarpium Granati are pulverized, mixed after sieving
Close uniformly, add Extraction solvent by feed liquid mass ratio 1: 5 ~ 1: 20, after soaking 1 ~ 2.5h together with Extraction solvent, under room temperature
Extracting with high pressure homogenization method machine, extracting solution is performing centrifugal separation on, and membrane separation concentrated to be reduced to extracting solution with quality of medicinal material ratio be 5:
1 ~ 1: 5, add with concentrate after extracting solution as weight 1.3-butanediol dissolve, filter, prepare Radix Scutellariae extract, stone
Pomegranate peel extract;Extraction solvent is water, ethanol, ethanol-water mixed solution.
Described gluconolactone (and) sodium benzoate be Lonza company of Switzerland produce gluconolactone (and) benzoic acid
Sodium.
Described alkali is in sodium hydroxide, potassium hydroxide, triethanolamine, sodium carbonate, sodium bicarbonate, aminomethyl propanol
Plant or multiple.
The preparation method of described a kind of anticorrosive composite, it is characterised in that: first Radix Scutellariae extract and Pericarpium Granati are extracted
Thing mix, add gluconolactone (and) sodium benzoate, alkali, after being uniformly dissolved, filter,.
The second object of the present invention is being used for above-mentioned a kind of anticorrosive composite in household chemicals, makes character steady
The household chemicals fixed, antiseptic effect is good.
For realizing the second object of the present invention, present invention employs following technical scheme: by above-mentioned a kind of anticorrosive composite
Be used for prepare household chemicals, it is characterised in that containing above-mentioned a kind of anticorrosive composite in defying age household chemicals, it is used
Amount is calculated as 0.1-20% with mass fraction, and preferable amount is calculated as 1-10% with mass fraction.
The dosage form of household chemicals is not particularly limited, and can be solution, emulsion, paste, foundation emulsion, spray, facial film etc..
The invention has the beneficial effects as follows: the compositions of the present invention has good antiseptic effect, and safe, non-stimulated,
Overcome the defect that current preservative is big to human body skin injury.
Detailed description of the invention
Below by way of specific embodiment come the present invention is further illustrated, but these embodiments simply to illustrate that,
It it not limitation of the present invention.
1 one kinds of anticorrosive composites (I) of embodiment
A kind of anticorrosive composite (I) forms as follows by weight percentage: gluconolactone (and) sodium benzoate 20%, sodium hydroxide
2%, Radix Scutellariae extract 40%, Pericarpium Granati extract 38%.
2 one kinds of anticorrosive composites (II) of embodiment
A kind of anticorrosive composite (II) forms as follows by weight percentage: gluconolactone (and) sodium benzoate 22%, aminomethyl third
Alcohol 2.5%, Radix Scutellariae extract 38%, Pericarpium Granati extract 37.5%.
3 one kinds of anticorrosive composites (III) of embodiment
A kind of anticorrosive composite (III) forms as follows by weight percentage: gluconolactone (and) sodium benzoate 20%, potassium hydroxide
2.5%, Radix Scutellariae extract 45%, Pericarpium Granati extract 32.5%.
Comparative example 1
Comparative composition forms as follows by weight percentage: gluconolactone (and) sodium benzoate 20%, sodium hydroxide 2%, water
78%。
Comparative example 2
Comparative composition forms as follows by weight percentage: Radix Scutellariae extract 40%, Pericarpium Granati extract 38%, water 22%.
Experimental example 1 bacteriostatic test
The bacterial strain used is Candida albicans (ATCC10231), escherichia coli (ATCC8739), staphylococcus aureus
(ATCC6538), bacillus pyocyaneus (ATCC9027), aspergillus niger (ATCC16404) are commercial.
Prepared by bacterium solution: each extracting waste candida mycoderma, escherichia coli, staphylococcus aureus, bacillus pyocyaneus, aspergillus niger new
Fresh slant culture is prepared as each bacterium solution, then ratio is turbid, general 0.5 the Maxwell unit of each bacterial concentration (be equivalent to 1.5 ×
108CFU/mL).
Fungistatic effect measures: pour in sterile petri dish by the nutrient agar after 15-20mL sterilizing, cooled and solidified
The rear injection above-mentioned bacterium solution of 0.1mL, smears with aseptic triangular glass rod and is uniformly expanded to media surface, is cultivating with sterile working
Primary surface is direct equidistant vertically puts Oxford cup, pressurizes gently so that it is contact tight with culture medium, adds in cup
0.2mL measuring samples, each sample do 3 parallel, simultaneously with normal saline do synchronization bacteriostatic experiment carry out blank, place
Corresponding incubator is cultivated antibacterial and is cultivated 48 hours at 37 DEG C, and fungus is being cultivated 3-5 days at 28 DEG C.Observed result on time, uses chi
Son measures the diameter of inhibition zone, takes its meansigma methods.Antibacterial circle diameter meansigma methods (mm) is shown in Table 1.
Table 1
Sample | Staphylococcus aureus | Bacillus pyocyaneus | Escherichia coli | Candida albicans | Aspergillus niger |
Comparative example 1 | 21.6 | 19.5 | 23.7 | 18.9 | 19.4 |
Comparative example 2 | 11.6 | 15.5 | 12.9 | 12.6 | 13.1 |
Embodiment 1 | 27.4 | 24.7 | 31.5 | 26.2 | 21.0 |
Embodiment 2 | 28.2 | 24.4 | 30.7 | 25.6 | 20.5 |
Embodiment 3 | 25.9 | 25.1 | 29.9 | 26.3 | 21.4 |
Five samples are tested by 3 parallel inhibition zones of 5 kinds of bacterial strains, and result of the test shows: the antibacterial circle diameter of embodiment 1-3 is equal
Big than comparative example 1-2, illustrates that the fungistatic effect of embodiment 1 and embodiment 2 is the most notable;Gram positive bacteria, negative bacterium,
The antibacterial circle diameter length of yeast and mycotic culture flat board is all at more than 20mm, and diameter length is comparatively average, says
The bright fungistatic effect executing example 1-3 has significant broad spectrum activity.
Embodiment 4 skin protection cream
Table 2 provides the skin protection cream formula of a kind of anticorrosive composite (I) containing the present invention.
Table 2
Material title | Mass fraction (%) |
Cetearyl alcohol olive oil acid esters | 2.0 |
Pyrusussuriensis smooth olive oil acid esters | 1.0 |
Cetearyl glucoside | 0.5 |
Miglyol 812 | 3.0 |
Isopropyl palmitate | 5.0 |
Olive oil | 2.0 |
Shea butter | 1.0 |
Glyceryl monostearate | 0.6 |
Hydrogenated polydecene | 2.0 |
Cyclomethicone | 4.0 |
Water | Surplus |
Allantoin | 0.1 |
DL-Panthenol | 0.50 |
1,3 butylene glycol | 5.0 |
Xanthan gum | 0.2 |
EDTA disodium | 0.02 |
Glycerol | 10.0 |
Hyaluronate sodium | 0.02 |
A kind of anticorrosive composite (I) | 1.2 |
Essence | 0.15 |
Preparation method:
(1) oil-soluble ingredients is mixed and heated to 80 DEG C be uniformly dissolved, for oil phase.
(2) water soluble ingredient is mixed and heated to 80 DEG C be uniformly dissolved, for oil phase.
(3) aqueous phase is added oil phase homogenizing 5min, is cooled to when 50 DEG C add essence and a kind of anticorrosive composite (I),
And homogenizing 2 minutes, stirring, it is down to 38 DEG C of dischargings, packs after ageing 24h,.
Embodiment 5 facial treatment milk
Table 3 provides the facial treatment milk formula of a kind of anticorrosive composite containing the present invention, the consumption mass fraction table of each material
Show.
Table 3
The preparation method of whitening and skin-protecting breast: by the dimethyl siloxane in formula table, isopropyl palmitate, Caprylic Capric
Ester, monoglyceride, stearic acid mix, and are heated to 80 DEG C, and fusing stirs, as oil phase;By the 1,2-in formula table the third two
Alcohol, a kind of anticorrosive composite (II), triethanolamine, deionized water mixing, be heated to 85 DEG C, and stirring and dissolving is uniform, as water
Phase.Oil phase and aqueous phase being added in emulsifying pot, stir, emulsifying homogeneous is after 6 minutes, when stirring is cooled to 50 DEG C, adds perfume
Essence, stirs, and is cooled to 38 DEG C,.
The preparation of embodiment 6 surfactant
Table 4 provides the surfactant formula of a kind of anticorrosive composite containing the present invention, and the consumption mass fraction of each material represents.
Table 4
Preparation method: deionized water is heated to 85 DEG C, adds hydroxyethyl cellulose, and stirring and dissolving is uniform, adds 1,2-the third two
Alcohol.When stirring is cooled to 50 DEG C, add other compositions, continue stirring and be cooled to 38 DEG C,.
The common surfactant of comparative example 3
Table 5 provides the common surfactant formula of the compositions not containing the present invention, and the consumption mass fraction of each material represents.
Table 5
Preparation method: deionized water is heated to 85 DEG C, adds hydroxyethyl cellulose, and stirring and dissolving is uniform, adds 1,2-the third two
Alcohol.When stirring is cooled to 50 DEG C, add other compositions, continue stirring and be cooled to 38 DEG C,.
Experimental example 2 preservation challenge evaluation experimental
1, experimental strain
Staphylococcus aureus ATCC 6538(staphylococcus aureus), Escherichia coli ATCC 8739
(escherichia coli), Pseudomonas aeruginosa ATCC 9027 (bacillus pyocyaneus), Candida albicans ATCC
10231 (candida albicanses), Aspergillus niger ATCC 9029 (Aspergillus niger).
2, the keeping of experimental strain and condition of culture
(1) antibacterial and candida albicans
Culture medium: TSB
Maintaining requirement: cold preservation 4 ~ 8 DEG C
Maintaining requirement: 2 months
(2) Aspergillus niger
Culture medium: PDB
Maintaining requirement: cold preservation 4 ~ 8 DEG C
Maintaining requirement: 2 months
3, bacterium solution manufacture method is used in test
(1) (test portion every gram of experiment is 10 to antibacterial liquid manufacture method7cfu )
Three kinds of antibacterials and Candida albicans respectively take 50 μ L add sterilized process 5mL TSB culture fluid in inoculate, then
Cultivate 48 hours at 37 DEG C of shaking tables, obtain the bacterium solution of each bacterium.According to 106, 107,108Three dilution factors by LB culture medium by it
Cultivate, then confirm the viable count of each bacterium solution.Each bacterium solution takes in the 50mL centrifuge tube that 1mL is added to and mixes, it is thus achieved that mixed bacteria liquid
(concentration of mixed bacteria liquid is for being preferably controlled in 1.0 × 109About cfu/mL).
(2) (test portion every gram of experiment is 10 to the manufacture method of fungus liquid5cfu )
Reference culture bacterium (Aspergillus niger) is inoculated in culture medium, is then placed on inside the incubator of 25 DEG C and cultivates spore fully
After son, being inoculated in culture fluid PDB10mL by the spore platinum inoculating loop of cultured black, fully concussion is uniformly, so
After inside culture medium, spore is scraped off.After the spore scraped off and fluid medium being sufficiently mixed, take bacterium above
Liquid is collected in centrifuge tube, obtains fungus liquid.By fungus liquid (about 107Cfu), after being diluted on PDA cultivation, confirm to deposit as far as possible
The bacterium number lived.
4, experimental technique
(1) preparation of sample
Anticorrosive composite prepared by embodiment 1,2,3 and comparative example 1,2 is separately added in table 6 formula, is uniformly dissolved and makes examination
Sample.
Table 6
(2) antibacterial preservative challenge test method
This laboratory reference household chemicals, toilet articles and fragrance association (CTFA) microbiological test methods be i.e.: household chemicals
Middle interpolation a certain amount of mixed microorganism bacteria suspension, adds mixed vaccine amount and is respectively as follows: antibacterial 3.0 × 107CFU/g (CFU/m1) and
Mycete 1.0 × 105CFU/g (CFU/m1)), mixed sample observes the survival feelings of microorganism in special time separation detection
Condition: 0 hour (i.e. inoculation after at once sampling), 7 days, 14 days, 21 days and 28 days result it is required that antibacterial reduction by 99. when the 7th day
9%, mycete reduces by 90%;And continuous decrease is zero to judge the antiseptic effect of preservative in 28 days, concrete judgement knot
Really reference table 7.
Table 7
Strain name | 0d | 7d | 14d | 21d | 28d |
Fungus (cfu/g) | 1.0×105 | ≤100 | 0 | 0 | 0 |
Antibacterial (cfu/g) | 3.0×107 | 0 | 0 | 0 | 0 |
5, result
The results are shown in Table shown in 8.
Table 8
As shown in Table 8, the sample made by embodiment 1,2,3 passed preservation challenge test, has potent antiseptic effect.
As time goes on, antibacterial and total number of fungi all have decline to the sample that comparative example 1,2 makes, and illustrate all have certain anticorrosion to imitate
Really, but do not tested by preservation challenge.
Experimental example 3 skin irritation evaluation experimental
With 40 women and 10 male as object, take in the coyote hole that 30mg sample is placed in speckle examination adhesive tape, sample will be equipped with immediately
Speckle examination adhesive tape start from bottom to be longitudinally affixed on the normal skin of left forearm, the lightest pressing room is to drive away air, and
Trier is made to be uniformly distributed.Labelling is carried out at test position, in order to observe.Every 24 hours patch skins once, open after paster half
Hour, then checked according to the term of CTFA guide (1981).6 patch experiments are carried out altogether, after patch skin terminates
6th day, in order to observe late response, carry out additional inspection.Data then utilize and check result for the last time, compare.
Identify and carry out for standard with table 9.Substances is respectively the surfactant of embodiment 6 and the common surfactant of comparative example 1, and result is such as
Shown in table 10.
Table 9
Grade | Symbol | Standard of perfection |
0 | - | Negative reaction: non-stimulated, without erythema |
1 | ± | Suspicious reaction: slight erythema |
2 | + | Weak positive reaction: erythema |
3 | ++ | Strong positive reaction: erythema, pimple, vesicle |
4 | +++ | Extremely strong positive reaction: serious edema, bulla |
Table 10
Lagging number of times | Comparative example 3 | Blank experiment | Embodiment 4 |
1 | 0 | 0 | |
2 | 1 time+ | 0 | 0 |
3 | 0 | 0 | |
4 | 1 time ± | 0 | 0 |
5 | 0 | 0 | |
6 | 0 | 0 | |
After end the 6th day | 1 time ± | 0 | 0 |
Add up to | 2 times ±, 1 time+ | 0 | 0 |
Result of the test shows, non-stimulated in the experiment of tested crowd's empty, and skin does not the most occur in the surfactant of embodiment 4 preparation
The phenomenon that skin stimulates, and the common surfactant of comparative example 1 preparation is to exist the irritant reaction of skin.Illustrate to use the present invention
The cosmetics prepared of compositions less than the cosmetics zest prepared by common preservatives, safer.
Claims (7)
1. an anticorrosive composite, it is characterised in that be made up of the component of following percentage by weight: gluconolactone (and) benzene first
Acid sodium 0.1-30%, alkali 0.1-10%, Radix Scutellariae extract 10-60, Pericarpium Granati extract 10-50%.
2. an anticorrosive composite, it is characterised in that be made up of the component of following percentage by weight: gluconolactone (and) benzene first
Acid sodium 1-25%, alkali 0.2-8%, Radix Scutellariae extract 15-50%, Pericarpium Granati extract 15-45%.
3. an anticorrosive composite, it is characterised in that be made up of the component of following percentage by weight: gluconolactone (and) benzene first
Acid sodium 5-20%, alkali 0.2-6%, Radix Scutellariae extract 20-50%, Pericarpium Granati extract 15-40%.
4. an anticorrosive composite, it is characterised in that comprise the component of following percentage by weight: gluconolactone (and) benzoic acid
Sodium 5-20%, alkali 0.3-5%, Radix Scutellariae extract 20-45, Pericarpium Granati extract 20-45%.
5., according to the Radix Scutellariae extract described in any one of claim 1-4, Pericarpium Granati extract, its preparation method is: by Radix Scutellariae,
Pericarpium Granati is pulverized, mix homogeneously after sieving, and adds Extraction solvent by feed liquid mass ratio 1: 5 ~ 1: 20, soaks together with Extraction solvent
After bubble 1 ~ 2.5h, extracting with high pressure homogenization method machine under room temperature, extracting solution is performing centrifugal separation on, and membrane separation concentrated being reduced to is extracted
Liquid is 5: 1 ~ 1: 5 with quality of medicinal material ratio, add with concentrate after extracting solution as weight 1.3-butanediol dissolve, mistake
Filter, prepares Radix Scutellariae extract, Pericarpium Granati extract;Extraction solvent is water, ethanol, ethanol-water mixed solution.
6. it is sodium hydroxide, potassium hydroxide, triethanolamine, sodium carbonate, bicarbonate according to the alkali described in any one of claim 1-4
One or more in sodium, aminomethyl propanol.
7. the application in household chemicals of a kind of anticorrosive composite described in any one of claim 1-4, it is characterised in that day
With containing a kind of anticorrosive composite described in any one of claim 1-4 in chemicals, its consumption is calculated as 0.1-with mass fraction
20%。
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Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
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CN106377467A (en) * | 2016-11-29 | 2017-02-08 | 佛山市芊茹化妆品有限公司 | Pomelo-peel-extract-containing anticorrosive bactericidal composition |
CN108685802A (en) * | 2018-08-07 | 2018-10-23 | 广东丸美生物技术股份有限公司 | Anticorrosive composite and its preparation method and application |
CN109925207A (en) * | 2019-01-02 | 2019-06-25 | 杭州犇鑫科技有限公司 | A kind of new food preservative composition and its preparation method and application |
-
2016
- 2016-03-14 CN CN201610145851.4A patent/CN105796404A/en active Pending
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中华人民共和国卫生部: "《化妆品管理及安全性和功效性评价》", 31 January 2007, 化学工业出版社 * |
刘军红 等: "生物碱提取、分离和纯化的研究进展", 《时珍国医国药》 * |
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Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106377467A (en) * | 2016-11-29 | 2017-02-08 | 佛山市芊茹化妆品有限公司 | Pomelo-peel-extract-containing anticorrosive bactericidal composition |
CN108685802A (en) * | 2018-08-07 | 2018-10-23 | 广东丸美生物技术股份有限公司 | Anticorrosive composite and its preparation method and application |
CN108685802B (en) * | 2018-08-07 | 2019-10-18 | 广东丸美生物技术股份有限公司 | Anticorrosive composite and its preparation method and application |
CN109925207A (en) * | 2019-01-02 | 2019-06-25 | 杭州犇鑫科技有限公司 | A kind of new food preservative composition and its preparation method and application |
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Application publication date: 20160727 |