CN107802523A - A kind of essential oil rod for eliminating bite by mosquitos sufferings and its preparation method and application - Google Patents
A kind of essential oil rod for eliminating bite by mosquitos sufferings and its preparation method and application Download PDFInfo
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- CN107802523A CN107802523A CN201711304452.9A CN201711304452A CN107802523A CN 107802523 A CN107802523 A CN 107802523A CN 201711304452 A CN201711304452 A CN 201711304452A CN 107802523 A CN107802523 A CN 107802523A
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- mosquitos
- bite
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/0216—Solid or semisolid forms
- A61K8/0229—Sticks
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/737—Galactomannans, e.g. guar; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/738—Cyclodextrins
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L9/00—Disinfection, sterilisation or deodorisation of air
- A61L9/01—Deodorant compositions
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L9/00—Disinfection, sterilisation or deodorisation of air
- A61L9/01—Deodorant compositions
- A61L9/013—Deodorant compositions containing animal or plant extracts, or vegetable material
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/02—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings containing insect repellants
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
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- Pest Control & Pesticides (AREA)
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Abstract
The present invention discloses a kind of essential oil rod for eliminating bite by mosquitos sufferings, in parts by weight, composed of the following components:3 10 parts of tween, 8 15 parts of distilled water, 0.2 1 parts of Basil Essential, 0.1 0.3 parts of citronella oil, 13 parts of cyclodextrin, 0.5 2 parts of alcohol, 0.18 0.5 parts of carragheen.A kind of essential oil rod for elimination bite by mosquitos sufferings that the present invention prepares, have and eliminate sufferings caused by bite by mosquitos, wind spot and function of driving mosquitoes effect in time, also with clean rooms, pure and fresh brains, oxidation resistant benefit.
Description
Technical field
The present invention relates to a kind of essential oil, more particularly to a kind of essential oil rod for eliminating bite by mosquitos sufferings and preparation method thereof and
Using.
Background technology
Mosquito main harm is to spread disease, and it is prevention and the effective way for reducing killing propagation disease to eliminate mosquito.Keep away
Mosquito amine can impact as an effective culicifuge, Metadelphene to the central nervous system of people, and the Metadelphene of high concentration is easy
Trigger epilepsy, the chemical synthesis preparation such as Metadelphene and dimethyl phthalate has certain excitant, and skin sensitivity, the person that has wound and pregnant baby want
Avoid using.For mosquito, a kind of plant-based medicine is researched and developed, harmless and good effect, is a urgent problem to be solved.
The content of the invention
In view of the above-mentioned problems of the prior art, the present invention provide it is a kind of eliminate bite by mosquitos sufferings essential oil rod and its
Preparation method and application, effectively eliminate sufferings, wind spot caused by bite by mosquitos.
In order to solve the above-mentioned technical problem, the present invention adopts the following technical scheme that:
A kind of essential oil rod for eliminating bite by mosquitos sufferings, it is in parts by weight, composed of the following components:Tween 3-10 parts, steam
Distilled water 8-15 parts, Basil Essential 0.2-1 parts, citronella oil 0.1-0.3 parts, cyclodextrin 1-3 parts, alcohol 0.5-2 parts, carragheen
0.18-0.5 parts.
As the further optimization of such scheme, the mass ratio of the distilled water and Basil Essential is 20:1.
A kind of essential oil rod for eliminating bite by mosquitos sufferings, it is in parts by weight, composed of the following components:5 parts of tween, distilled water
10 parts, 0.5 part of Basil Essential, 0.25 part of citronella oil, 1.2 parts of cyclodextrin, 1 part of alcohol, 0.3 part of carragheen.
A kind of essential oil rod for eliminating bite by mosquitos sufferings, it is in parts by weight, composed of the following components:7 parts of tween, distilled water
12 parts, 0.6 part of Basil Essential, 0.22 part of citronella oil, 1.5 parts of cyclodextrin, 0.8 part of alcohol, 0.3 part of carragheen.
As the further optimization of such scheme, a kind of essential oil rod for eliminating bite by mosquitos sufferings, the Basil Essential
Component, in parts by weight, including following components:44.1 parts of hexadecylic acid ethyl acetate, 17.1 parts of terpinyl acetate, geraniol
3.0% part, 9.9 parts of (s) -2,5,5,8- tetramethyl -1,2,3,6- tetrahydro Azulene -4- ketone.Thin hair sweet basil is cultivar, through peace
Emblem university of TCM professor is identified, Basil Essential is prepared using steam distillation.
A kind of preparation method for the essential oil rod for eliminating bite by mosquitos sufferings, comprises the following steps:
(1), tween, distilled water are placed in test tube, then are placed in pipette, extract Basil Essential in test tube, mixture fills
Divide and mix, it is standby;
(2), cyclodextrin, citronella oil are added in distilled water, are heated to 55-60 DEG C, is stirred continuously until uniformly;
(3), the solution obtained by step (1) and step (2) is mixed, 80 DEG C -90 DEG C is heated to, adds appropriate carragheen,
Shake up, pour into sizing container and obtain essential oil rod.
A kind of application for the essential oil rod for eliminating bite by mosquitos sufferings, a kind of essential oil rod of described elimination bite by mosquitos sufferings
For treating caused sufferings after bite by mosquitos;Eliminate wind spot caused by bite by mosquitos.
Compared with the prior art, essential oil rod of a kind of elimination bite by mosquitos sufferings of the invention and preparation method thereof is beneficial
Effect is embodied in:
(1) a kind of, the essential oil rod of elimination bite by mosquitos sufferings of the invention, using basil, oil of Cymbopogon winterianus, cyclodextrin and
Carragheen etc., with reference to essential oil slow release method, essential oil gel stick has as externally applied liniment and eliminates pain caused by bite by mosquitos in time
Itch, the effect of wind spot and function of driving mosquitoes, be provided simultaneously with function of driving mosquitoes.
(2) a kind of, the essential oil rod of elimination bite by mosquitos sufferings of the invention, can pure and fresh brains, clean rooms, it is anti-oxidant
Benefit.
(3), a kind of essential oil rod technique of elimination bite by mosquitos sufferings of the invention is easy to standardize, is adapted to extensive life
Production.To improving Competitive Products, effectively extend volume growth, promote interprise's intensive management and technological progress etc. that all there is weight
Big realistic meaning and social effect.
Embodiment
To make the object, technical solutions and advantages of the present invention of greater clarity, below by embodiment, the present invention is entered
Row is further described.However, it should be understood that the specific embodiments described herein are merely illustrative of the present invention, and do not have to
In limitation the scope of the present invention.
Embodiment 1
A kind of essential oil rod for eliminating bite by mosquitos sufferings, it is in parts by weight, composed of the following components:5 parts of tween, distilled water
10 parts, 0.5 part of Basil Essential, 0.25 part of citronella oil, 1.2 parts of cyclodextrin, 1 part of alcohol, 0.3 part of carragheen.
In this preferred embodiment, a kind of preparation method for the essential oil rod for eliminating bite by mosquitos sufferings, comprise the following steps:
(1), tween, distilled water are placed in test tube, then are placed in pipette, extract Basil Essential in test tube, mixture fills
Divide and mix, it is standby;
(2), cyclodextrin, citronella oil are added in distilled water, are heated to 55-60 DEG C, is stirred continuously until uniformly;
(3), the solution obtained by step (1) and step (2) is mixed, 80 DEG C -90 DEG C is heated to, adds appropriate carragheen,
Shake up, pour into sizing container and obtain essential oil rod.
Wherein, citronella oil is commercial goods, and tween, cyclodextrin, carragheen, alcohol are ommercially available AR, each component
Proportion is converted as mass percent.
Embodiment 2
A kind of essential oil rod for eliminating bite by mosquitos sufferings, it is in parts by weight, composed of the following components:7 parts of tween, distilled water
12 parts, 0.6 part of Basil Essential, 0.22 part of citronella oil, 1.5 parts of cyclodextrin, 0.8 part of alcohol, 0.3 part of carragheen.
In this preferred embodiment, a kind of preparation method for the essential oil rod for eliminating bite by mosquitos sufferings, comprise the following steps:
(1), tween, distilled water are placed in test tube, then are placed in pipette, extract Basil Essential in test tube, mixture fills
Divide and mix, it is standby;
(2), cyclodextrin, citronella oil are added in distilled water, are heated to 55-60 DEG C, is stirred continuously until uniformly;
(3), the solution obtained by step (1) and step (2) is mixed, 80 DEG C -90 DEG C is heated to, adds appropriate carragheen,
Shake up, pour into sizing container and obtain essential oil rod.
Wherein, citronella oil is commercial goods, and tween, cyclodextrin, carragheen, alcohol are ommercially available AR, each component
Proportion is converted as mass percent.
Application test based on embodiment 1
8 points 2 groups of rabbit, wherein well word is drawn as damaged skin group by the use of blade by four skin depilatory areas, four are in addition
Intact skin group, hair removal section is only applied to the essential oil 4.0ml/ of embodiment 1, observed in 14 days by day, the behavioral activity of two groups of rabbit,
Diet, fur gloss and body weight have no effect, and no rabbit is dead, does not occur any acute toxic reaction.
Embodiment 1 eliminates wind spot observation caused by bite by mosquitos
6 points 2 groups of rabbit, wherein well word is drawn as damaged skin group by the use of blade by 3 skin depilatory areas, 3 have been in addition
Whole skin group, go to hair-fields to apply the essential oil 1ml of embodiment 1, after 24h is administered, remaining tested material is removed with warm water, and in 1h, 24h,
48h, 72h hour, record smear situations such as position whether there is erythema, oedema.As a result intact skin group is in the equal nothing of each observing time point
Erythema and oedema phenomenon occur.There is inadequate visible erythema the essential oil smear zone of embodiment 1 of damaged skin in 1h, and 24h recovers;
Illustrate this product to rabbit no skin irritation, but can recover.
The skin hypersensitivity of embodiment 1 is observed
Albino guinea-pig left dorsal unhairing, the essential oil 0.2ml of embodiment 1 is given by dermal application method, continue 6h, and in administration 24
After hour, with method repeat administration, administration is excited within the 28th day within the 14th day, the essential oil 0.2ml of embodiment 1 is applied on the right side of guinea pig back
Go hair-fields, tested material to be washed away after 6h, is observed at once, then observed again in 24h, 48h, 72h, as a result skin is without allergy such as erythema
Phenomenon produces.It can be seen that the essential oil of embodiment 1 does not produce sensitization.
The mosquito repellent of embodiment 1 is tested
The qualified tester of four attacks, arm exposure 40mm × 40mm emgloves is worn, by 1.5 μ l/cm2
Dose uniformity smear embodiment 1, after 2h, hand is stretched into the qualified aedes albopictus of attack whether there is into 2min in mosquito cage, observation
Mosquito comes to stop to fall to suck blood.Afterwards at interval of 1h tests once.As long as have a mosquito come to suck blood sentence keep away mosquito failure.Note
Record its effective protecting time (h).When taking effective protection of the average value of the effective protecting time of four bit test persons as embodiment 1
Between, traditional essential wind oil is tested with method.The effective protecting time of acetonideexample 1 is 6h, effective guarantor of traditional essential wind oil
The shield time is 3h.
The crowd of embodiment 1 tries out
40 crowds for suffering from red and swollen heat pain caused by bite by mosquitos, using the essential oil of embodiment 1,40 patients are through treating scabies
Itch and be obviously improved with local red and swollen phenomenon.Feel in use without generation is uncomfortable.
The essential oil rod of a kind of elimination bite by mosquitos sufferings of the present invention, using basil, oil of Cymbopogon winterianus, cyclodextrin and OK a karaoke club
Glue etc., with reference to essential oil slow release method, essential oil gel stick as externally applied liniment, have eliminate in time sufferings caused by bite by mosquitos,
Wind spot and function of driving mosquitoes effect, are provided simultaneously with function of driving mosquitoes.
The foregoing is merely illustrative of the preferred embodiments of the present invention, is not intended to limit the invention, all essences in the present invention
Any modification, equivalent substitution or improvement made within refreshing and principle etc., should be included in the scope of the protection.
Claims (7)
1. a kind of essential oil rod for eliminating bite by mosquitos sufferings, it is characterised in that in parts by weight, composed of the following components:Tween
3-10 parts, distilled water 8-15 parts, Basil Essential 0.2-1 parts, citronella oil 0.1-0.3 parts, cyclodextrin 1-3 parts, alcohol 0.5-2 parts,
Carragheen 0.18-0.5 parts.
2. it is according to claim 1 it is a kind of eliminate bite by mosquitos sufferings essential oil rod, it is characterised in that the distilled water with
The mass ratio of Basil Essential is 20:1.
3. a kind of essential oil rod for eliminating bite by mosquitos sufferings, it is characterised in that in parts by weight, composed of the following components:Tween 5
Part, 10 parts of distilled water, 0.5 part of Basil Essential, 0.25 part of citronella oil, 1.2 parts of cyclodextrin, 1 part of alcohol, 0.3 part of carragheen.
4. a kind of essential oil rod for eliminating bite by mosquitos sufferings, it is characterised in that in parts by weight, composed of the following components:Tween 7
Part, 12 parts of distilled water, 0.6 part of Basil Essential, 0.22 part of citronella oil, 1.5 parts of cyclodextrin, 0.8 part of alcohol, 0.3 part of carragheen.
5. the essential oil rod based on a kind of any described elimination bite by mosquitos sufferings of claim 1-4, it is characterised in that described
The component of Basil Essential, in parts by weight, including following components:44.1 parts of hexadecylic acid ethyl acetate, 17.1 parts of terpinyl acetate,
3.0% part of geraniol, 9.9 parts of (s) -2,5,5,8- tetramethyl -1,2,3,6- tetrahydro Azulene -4- ketone.
6. the preparation method of the essential oil rod based on a kind of any described elimination bite by mosquitos sufferings of claim 1-4, its feature
It is, comprises the following steps:
(1), tween, distilled water are placed in test tube, then are placed in pipette, extract Basil Essential in test tube, mixture is fully mixed
It is even, it is standby;
(2), cyclodextrin, citronella oil are added in distilled water, are heated to 55-60 DEG C, is stirred continuously until uniformly;
(3), the solution obtained by step (1) and step (2) is mixed, 80 DEG C -90 DEG C is heated to, adds appropriate carragheen, shake up,
Pour into sizing container and obtain essential oil rod.
7. the application of the essential oil rod based on a kind of any described elimination bite by mosquitos sufferings of claim 1-4, it is characterised in that
A kind of essential oil rod of described elimination bite by mosquitos sufferings is used to treat caused sufferings after bite by mosquitos;Bite by mosquitos is eliminated to draw
The wind spot risen.
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CN201711304452.9A CN107802523A (en) | 2017-12-11 | 2017-12-11 | A kind of essential oil rod for eliminating bite by mosquitos sufferings and its preparation method and application |
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CN201711304452.9A CN107802523A (en) | 2017-12-11 | 2017-12-11 | A kind of essential oil rod for eliminating bite by mosquitos sufferings and its preparation method and application |
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Cited By (1)
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CN115252479A (en) * | 2022-08-15 | 2022-11-01 | 王德立 | Itching-relieving inflammation-diminishing mosquito-repellent lotion formula |
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CN115252479A (en) * | 2022-08-15 | 2022-11-01 | 王德立 | Itching-relieving inflammation-diminishing mosquito-repellent lotion formula |
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Application publication date: 20180316 |