CN107735081A - 用于治疗抑郁症的方法和药盒 - Google Patents

用于治疗抑郁症的方法和药盒 Download PDF

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Publication number
CN107735081A
CN107735081A CN201680029082.XA CN201680029082A CN107735081A CN 107735081 A CN107735081 A CN 107735081A CN 201680029082 A CN201680029082 A CN 201680029082A CN 107735081 A CN107735081 A CN 107735081A
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China
Prior art keywords
patient
esketamine
chinese mugwort
during
induction period
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CN201680029082.XA
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English (en)
Chinese (zh)
Inventor
J.辛格
I.卡尔斯
E.达伊
W.C.德雷维特斯
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Janssen Pharmaceutica NV
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Janssen Pharmaceutica NV
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Publication of CN107735081A publication Critical patent/CN107735081A/zh
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Psychiatry (AREA)
  • Organic Chemistry (AREA)
  • Dermatology (AREA)
  • Pulmonology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Treatments Of Macromolecular Shaped Articles (AREA)
  • Emergency Medicine (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
CN201680029082.XA 2015-05-20 2016-05-20 用于治疗抑郁症的方法和药盒 Pending CN107735081A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562164026P 2015-05-20 2015-05-20
US62/164026 2015-05-20
PCT/US2016/033404 WO2016187491A1 (en) 2015-05-20 2016-05-20 Methods and kits for treating depression

Publications (1)

Publication Number Publication Date
CN107735081A true CN107735081A (zh) 2018-02-23

Family

ID=57320901

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201680029082.XA Pending CN107735081A (zh) 2015-05-20 2016-05-20 用于治疗抑郁症的方法和药盒

Country Status (20)

Country Link
US (1) US20160338977A1 (https=)
EP (1) EP3297618A4 (https=)
JP (1) JP2018515557A (https=)
KR (1) KR20180008634A (https=)
CN (1) CN107735081A (https=)
AU (3) AU2016263598A1 (https=)
CA (1) CA2986477A1 (https=)
CL (1) CL2017002904A1 (https=)
CO (1) CO2017011564A2 (https=)
DO (1) DOP2017000268A (https=)
EA (1) EA201792545A1 (https=)
EC (1) ECSP17077930A (https=)
GT (1) GT201700246A (https=)
HK (1) HK1252937A1 (https=)
IL (1) IL255463A (https=)
MA (1) MA42135A (https=)
MX (1) MX2017014797A (https=)
PE (1) PE20180260A1 (https=)
PH (1) PH12017502103A1 (https=)
WO (1) WO2016187491A1 (https=)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112188889A (zh) * 2018-06-27 2021-01-05 克雷西奥生物科技有限公司 治疗重度抑郁症的方法
CN112702995A (zh) * 2018-10-05 2021-04-23 克雷西奥生物科技有限公司 治疗重度抑郁症的艾氯胺酮的治疗方案
CN113038941A (zh) * 2018-09-28 2021-06-25 赛隆制药股份公司 用于通过肺部施用治疗抑郁症的方法中的氯胺酮组合物
CN114126595A (zh) * 2019-03-05 2022-03-01 杨森制药公司 用于治疗抑郁症的艾司氯胺酮
US12076300B2 (en) 2019-12-30 2024-09-03 Clexio Biosciences Ltd. Dosage regime with esketamine for treating major depressive disorder
US12478592B2 (en) 2019-12-30 2025-11-25 Clexio Biosciences Ltd. Dosage regime with esketamine for treating neuropsychiatric or neurological conditions

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20140274981A1 (en) 2013-03-15 2014-09-18 Janssen Pharmaceutica Nv Pharmaceutical composition of s-ketamine hydrochloride
KR20170040800A (ko) 2014-08-13 2017-04-13 얀센 파마슈티카 엔.브이. 우울증 치료 방법
AU2015318123A1 (en) 2014-09-15 2017-03-30 Janssen Pharmaceutica Nv Val66Met (SNP rs6265) genotype specific dosing regimens and methods for the treatment of depression
US20160332962A1 (en) 2015-05-13 2016-11-17 Janssen Pharmaceutica Nv (s)-csa salt of s-ketamine, (r)-csa salt of s-ketamine and processes for the preparation of s-ketamine
CN107847469A (zh) 2015-06-27 2018-03-27 美国神农制药责任有限公司 氯胺酮透皮递送系统
US20200009081A1 (en) 2017-09-13 2020-01-09 Janssen Pharmaceutica N.V. Delivery Of Esketamine For The Treatment Of Depression
KR20240011237A (ko) * 2017-12-22 2024-01-25 얀센 파마슈티카 엔브이 우울증 치료를 위한 에스케타민
ES2907692T3 (es) 2017-12-29 2022-04-26 Celon Pharma Sa Composición de ketamina de polvo seco para su administración por vía pulmonar en la depresión resistente al tratamiento
WO2020070547A1 (en) * 2018-10-05 2020-04-09 Clexio Biosciences Ltd. Dosage regime of esketamine for treating major depressive disorder
EP3863617A1 (en) 2018-10-11 2021-08-18 Clexio Biosciences Ltd. Esketamine for use in treating major depressive disorder
CN114286674A (zh) * 2019-08-28 2022-04-05 杨森制药公司 用于治疗患有包括自杀倾向在内的重性抑郁障碍的患者的艾司氯胺酮
TW202135787A (zh) 2019-12-12 2021-10-01 比利時商健生藥品公司 艾氯胺酮調配物及製備與儲存的方法
JP7840873B2 (ja) * 2020-05-28 2026-04-06 ヤンセン ファーマシューティカ エヌ．ベー． うつ病の治療方法
GB202019952D0 (en) * 2020-12-17 2021-02-03 Neurocentrx Pharma Ltd Novel compositions
WO2022235576A1 (en) * 2021-05-03 2022-11-10 Wang Michael Z Methods and compositions for treating depression

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101466364A (zh) * 2006-03-22 2009-06-24 纽约大学西奈山医学院 鼻内施用氯胺酮治疗抑郁症
WO2014169272A1 (en) * 2013-04-12 2014-10-16 Icahn School Of Medicine At Mount Sinai Method for treating post-traumatic stress disorder
CN104519878A (zh) * 2012-03-12 2015-04-15 詹森药业有限公司 用于治疗顽固性或难治性抑郁症的艾氯胺酮
WO2016044150A1 (en) * 2014-09-15 2016-03-24 Janssen Pharmaceutica Nv VAL66MET (SNP rs6265) GENOTYPE SPECIFIC DOSING REGIMENS AND METHODS FOR THE TREATMENT OF DEPRESSION

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20110038807A1 (en) * 2009-08-14 2011-02-17 Demitri Papolos Compositions and methods for treating bipolar disorder
WO2013003669A2 (en) * 2011-06-30 2013-01-03 University Of South Florida Compositions, methods of use, and methods of treatment
EP2830604A4 (en) * 2012-03-30 2015-08-19 Gen Hospital Corp COMPOSITIONS WITH SCOPOLAMINE AND KETAMINE FOR THE TREATMENT OF DEPRESSIONS

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101466364A (zh) * 2006-03-22 2009-06-24 纽约大学西奈山医学院 鼻内施用氯胺酮治疗抑郁症
CN104519878A (zh) * 2012-03-12 2015-04-15 詹森药业有限公司 用于治疗顽固性或难治性抑郁症的艾氯胺酮
WO2014169272A1 (en) * 2013-04-12 2014-10-16 Icahn School Of Medicine At Mount Sinai Method for treating post-traumatic stress disorder
WO2016044150A1 (en) * 2014-09-15 2016-03-24 Janssen Pharmaceutica Nv VAL66MET (SNP rs6265) GENOTYPE SPECIFIC DOSING REGIMENS AND METHODS FOR THE TREATMENT OF DEPRESSION

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN112188889A (zh) * 2018-06-27 2021-01-05 克雷西奥生物科技有限公司 治疗重度抑郁症的方法
US12036189B2 (en) 2018-06-27 2024-07-16 Clexio Biosciences Ltd. Method of treating major depressive disorder
CN113038941A (zh) * 2018-09-28 2021-06-25 赛隆制药股份公司 用于通过肺部施用治疗抑郁症的方法中的氯胺酮组合物
CN112702995A (zh) * 2018-10-05 2021-04-23 克雷西奥生物科技有限公司 治疗重度抑郁症的艾氯胺酮的治疗方案
US11865088B2 (en) 2018-10-05 2024-01-09 Clexio Biosciences Ltd. Method of treating major depressive disorder
US11957645B2 (en) 2018-10-05 2024-04-16 Clexio Biosciences Ltd. Method of treating major depressive disorder
US12016832B2 (en) 2018-10-05 2024-06-25 Clexio Biosciences Ltd. Method of treating major depressive disorder
CN114126595A (zh) * 2019-03-05 2022-03-01 杨森制药公司 用于治疗抑郁症的艾司氯胺酮
US12076300B2 (en) 2019-12-30 2024-09-03 Clexio Biosciences Ltd. Dosage regime with esketamine for treating major depressive disorder
US12268658B2 (en) 2019-12-30 2025-04-08 Clexio Biosciences Ltd. Dosage regime with esketamine for treating major depressive disorder
US12478592B2 (en) 2019-12-30 2025-11-25 Clexio Biosciences Ltd. Dosage regime with esketamine for treating neuropsychiatric or neurological conditions

Also Published As

Publication number Publication date
AU2016263598A1 (en) 2017-11-23
GT201700246A (es) 2019-07-29
CL2017002904A1 (es) 2018-04-20
IL255463A (en) 2018-01-31
KR20180008634A (ko) 2018-01-24
JP2018515557A (ja) 2018-06-14
EA201792545A1 (ru) 2018-05-31
ECSP17077930A (es) 2018-02-28
PE20180260A1 (es) 2018-02-05
CO2017011564A2 (es) 2018-04-19
DOP2017000268A (es) 2018-04-15
US20160338977A1 (en) 2016-11-24
HK1252937A1 (zh) 2019-06-06
EP3297618A1 (en) 2018-03-28
PH12017502103A1 (en) 2018-05-07
AU2021215155A1 (en) 2021-09-02
CA2986477A1 (en) 2016-11-24
AU2016263598A8 (en) 2017-11-30
AU2023237026A1 (en) 2023-10-12
EP3297618A4 (en) 2019-01-23
WO2016187491A1 (en) 2016-11-24
MA42135A (fr) 2018-03-28
MX2017014797A (es) 2018-02-15

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Application publication date: 20180223