CN107711856A - A kind of composition containing matrine - Google Patents
A kind of composition containing matrine Download PDFInfo
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- CN107711856A CN107711856A CN201710914694.3A CN201710914694A CN107711856A CN 107711856 A CN107711856 A CN 107711856A CN 201710914694 A CN201710914694 A CN 201710914694A CN 107711856 A CN107711856 A CN 107711856A
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- matrine
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A40/00—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production
- Y02A40/10—Adaptation technologies in agriculture, forestry, livestock or agroalimentary production in agriculture
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- Life Sciences & Earth Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Health & Medical Sciences (AREA)
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- General Health & Medical Sciences (AREA)
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Abstract
The invention discloses a kind of composition containing matrine, compound A is：A1：The tetrahydropyridine of (1S, 3S) N ' (4 chlorobenzene methylene) the 1 methyl 2,3,4,9 simultaneously formylhydrazine (VII 6) of [3,4 b] indoles 3；A2：The tetrahydropyridine of (1S, 3S) N ' (cyclohexylmethylene) the 1 methyl 2,3,4,9 simultaneously formylhydrazine (VII 6) of [3,4 b] indoles 3.Calculate by weight percentage, the percentage by weight that matrine accounts for complex composition is 0.05%~5%, and the percentage by weight that compound A accounts for complex composition is 0.1%~80%.The percentage by weight that active ingredient matrine and compound A account for total composition is 0.15%~85%.Said composition can be used for the virosis of preventing and treating various crop, such as tomato, corn, tobacco, while to putting forward the resistance such as the high drought resisting of crop, high temperature resistance, regulating crop growth, Accelerate bloom, raising fruit yield and quality have good effect.
Description
Technical field
The present invention relates to a kind of composition pesticide, and using matrine and compound A as active ingredient, said composition can be used for preventing
The Disease of fruit tree, vegetables, field crop is controlled, the resistance of crop can also be effectively improved, regulating crop growth, promoted out
Flower, improve yield, improve fruit quality etc..
Background technology
Matrine is made of the real extraction through organic solvents such as ethanol of root, stem, leaf fruit of Chinese herbal medicine kuh-seng, is biology
Alkali, generally Banlangen, composition mainly has matrine, oxymatrine, sophocarpine, N-Oxysophocarpine, Sophoridine etc., with hardship
Join alkali, the content highest of oxymatrine.Matrine is agricultural chemical of natural plant, and insect once touches this medicine, i.e., in paralysis nerve
Pivot, then make polypide protein coagulating, block polypide stomata, insect is choked to death, this product is broad spectrum disinfestation to people and animals' low toxicity
Agent, there is stomach toxicity and action of contace poison, and to the viral inhibitory action having.Meet agricultural sustainable development direction, it is domestic at present
Kuh-seng alkali preparation have 0.3% aqueous matrine solution, 0.8% aqueous matrine solution, 1% kuh-seng aqueous slkali, 1.1% kuh-seng aqueous slkali,
1.1% matrine pulvis etc., these medicine based on herbs have been supplied in preventing and treating vegetables, fruit tree, tealeaves, the crop such as tobacco some insects
Obtain good preventive effect.
Compound A:In the structure containing acylhydrazone A1：Tetrahydro-beta-carboline class compound (chemical name：(1S, 3S)-N- (4-
Chlorobenzene methylene) -1- methyl -2,3,4,9- tetrahydropyridines simultaneously [3,4-b] indoles -3- formylhydrazines (VII-6) and A2：(1S,
Simultaneously [3,4-b] indoles -3- formylhydrazines (VII-6) are right for 3S)-N '-(cyclohexylmethylene) -1- methyl -2,3,4,9- tetrahydropyridines
Tobacco mosaic virus (TMV) has extraordinary bioactivity.The tetrahydro-beta-carboline class compound of the structure containing acylhydrazone is easily absorbed by plants,
It is degradable in the environment, have good Environmental compatibility.
(1S, 3S)-N- (4- chlorobenzenes methylene) -1- methyl -2,3,4,9- tetrahydropyridines simultaneously [3,4-b] indoles -3- first
Hydrazide structure formula：
(1S, 3S)-N '-(cyclohexylmethylene) -1- methyl -2,3,4,9- tetrahydropyridines simultaneously [3,4-b] indoles -3- formyls
Hydrazine structural formula：
The content of the invention
Based on case above, it is an object of the invention to provide a kind of composition containing matrine and compound A, can be used for
Fruit tree, vegetables, the virosis of field crop are prevented and treated, and drug effect significantly improves, and can also effectively improve the resistance of crop, adjusts
Plant growth is saved, rush blooms, improves yield, improves fruit quality etc..
To achieve these goals, the technical solution used in the present invention is as follows：
A kind of composition containing matrine, active ingredient are matrine and compound A, wherein compound A1：(1S,3S)-
N '-(4- chlorobenzenes methylene) -1- methyl -2,3,4,9- tetrahydropyridines simultaneously [3,4-b] indoles -3- formylhydrazines (VII-6)；A2：
(1S, 3S)-N '-(cyclohexylmethylene) -1- methyl -2,3,4,9- tetrahydropyridines simultaneously [3,4-b] indoles -3- formylhydrazines (VII-
6)。
Calculate by weight percentage, the percentage by weight that matrine accounts for complex composition is 0.05%~5%, and compound A is accounted for
The percentage by weight of complex composition is 0.1%~80%.
A kind of described composition containing matrine, its active ingredient account for the percentage by weight of total composition for 0.15%~
85%.
A kind of described composition containing matrine, its formulation be aqua, wettable powder, suspending agent, water dispersible granules,
Any one in pulvis.
Matrine has inhibitory action to virus in said composition, and compound A has good activity to mix both to virus
The virosis of fruit tree, vegetables and field crop can be effectively prevented and treated afterwards, and can improve crop anti-adversity, promoted plant growth, carried
High yield.Compared with prior art, had the beneficial effect that caused by the present invention：Expand the use of matrine and compound A single doses
Scope.Matrine and compound A compoundings, can effectively improve the drug effect of single dose, and effectively delay to prevent caused by single medicament use
Imitate the problems such as poor, while more promote the growth of crop.
Embodiment
In example of formulations, listed percentage is weight percentage.
Embodiment 1
The preparation of 0.4% kuh-seng alkali cpd A1 aquas
Raw material forms：0.3% matrine, 0.1% compound A1,5% surfactant sodium dodecyl base benzene sulfonic acid, deionization
Water is mended to 100%.Above-mentioned material is well mixed in kettle in mixing according to corresponding ratio, that is, active constituent content is made and is
4% kuh-seng alkali cpd A1 aquas.
Embodiment 2
The preparation of 2.4% kuh-seng alkali cpd A2 soluble concentrates
Raw material forms：2% matrine, 0.4% compound A2,7% agriculture breast 1601#, 5% cyclohexanone are mended to 100%.It is above-mentioned
Material is well mixed in kettle in mixing according to corresponding ratio, that is, it is 24% kuh-seng alkali cpd that active constituent content, which is made,
A2 soluble concentrates.
Embodiment 3
The preparation of 9% kuh-seng alkali cpd A1 wettable powders
Raw material forms：1.5% matrine, 7.5% compound A1,8% lignosulfonates, 5% alkylsulfonate, 8%
Citrate, diatomite are mended to 100%.It is well mixed again through air-flow crushing after above-mentioned mechanical mass is crushed, that is, is made effective
Component content is 9% kuh-seng alkali cpd A1 wettable powders.
Embodiment 4
The preparation of 18% kuh-seng alkali cpd A2 wettable powders
Raw material forms：4.1% matrine, 13.9% compound A2,8% lignosulfonates, 7% alkylsulfonate,
10% citrate, diatomite are mended to 100%.It is well mixed, that is, is made through air-flow crushing again after above-mentioned mechanical mass is crushed
Active constituent content is 18% kuh-seng alkali cpd A2 wettable powders.
Embodiment 5
The preparation of 21% kuh-seng alkali cpd A1 wettable powders
Raw material forms：3.2% matrine, 17.8% compound A1,8% lignosulfonates, 7% alkylsulfonate,
12% citrate, diatomite are mended to 100%.It is well mixed, that is, is made through air-flow crushing again after above-mentioned mechanical mass is crushed
Active constituent content is 30% kuh-seng alkali cpd A1 wettable powders.
Embodiment 6
The preparation of 80% kuh-seng alkali cpd A2 wettable powders
Raw material forms：12.2% matrine, 67.8% compound A2,8% lignosulfonates, 7% alkylsulfonate,
12% citrate, diatomite are mended to 100%.It is well mixed, that is, is made through air-flow crushing again after above-mentioned mechanical mass is crushed
Active constituent content is 30% kuh-seng alkali cpd A2 wettable powders.
Embodiment 7
The preparation of 13% kuh-seng alkali cpd A1 suspending agents
Raw material forms：1.8% matrine, 11.2% compound A1,6% sodium lignin sulfonate, 1.2% pull open powder, 1% Huang
Virgin rubber, 1%SAG622 organosilicons, 5% glycerine, 0.5% sodium tripolyphosphate, remaining is supplied with deionized water, is routinely suspended
It is 13% kuh-seng alkali cpd A1 suspending agents that the agent mode of production, which is prepared and active constituent content is made,.
Embodiment 8
The preparation of 38% kuh-seng alkali cpd A2 suspending agents
Raw material forms：6% matrine, 32% compound A2,6% sodium lignin sulfonate, 1.2% pull open powder, 1% xanthan
Glue, 1%SAG622 organosilicons, 5% glycerine, 0.5% sodium tripolyphosphate, remaining is supplied with deionized water, routinely suspending agent
It is 18% kuh-seng alkali cpd A2 suspending agents that the mode of production, which is prepared and active constituent content is made,.
Embodiment 9
The preparation of 6% kuh-seng alkali cpd A1 water dispersible granules
Raw material forms：3.5% matrine, 2.5% compound A1,10% lignosulfonates, 6% alkylsulfonate, 5%
Glucose, 4% cornstarch, kaolin and white carbon are mended to 100%.Above-mentioned material is crushed with micro jet, passed through
Mediate, then add in fluidized-bed granulation dryer and be granulated, dry, sieve, that is, it is 6% kuh-seng that active constituent content, which is made,
Alkali cpd A1 water dispersible granules.
Embodiment 10
The preparation of 85% kuh-seng alkali cpd A2 water dispersible granules
Raw material forms：5% matrine, 80% compound A2,6% alkylnaphthalene sulfonate, 3% naphthalene sulfonate, 3% corn form sediment
Powder, kaolin are mended to 100%.Above-mentioned material is crushed with micro jet, through mediating, fluidized bed prilling is then added and does
It is granulated, dried, sieved in dry machine, that is, it is 85% kuh-seng alkali cpd A2 pulvis that active constituent content, which is made,.
Embodiment 11
The preparation of 20% kuh-seng alkali cpd A1 pulvis
Raw material forms：1.2% matrine, 18.8% compound A1,6% alkylnaphthalene sulfonate, 3% naphthalene sulfonate, 3% jade
Rice starch, kaolin are mended to 100%.Above-mentioned material is crushed with micro jet, that is, active constituent content, which is made, is
20% kuh-seng alkali cpd A1 pulvis.
Embodiment 12
The preparation of 83% kuh-seng alkali cpd A1 pulvis
Raw material forms：3% matrine, 80% compound A1,6% alkylnaphthalene sulfonate, 3% naphthalene sulfonate, 3% corn form sediment
Powder, kaolin are mended to 100%.Above-mentioned material is crushed with micro jet, that is, it is 83% bitter that active constituent content, which is made,
Join alkali cpd A1 pulvis.
In order to verify prevention effect of the present invention to virosis, respectively to tomato virus disease, Summer squash virus, color green pepper disease
Viral disease carries out field efficacy checking.The result is as follows：
Field test embodiment one：The field control effectiveness test field of matrine and compound A compositions to tomato virus disease
Measure
After the composition of different content, different compound A and matrine is re-dubbed 5 kinds of different formulations, in tomato virus
Sick early stage carries out foliar spray, and every mu is watered 15L, and comparison medicament is 2% aqueous matrine solution single dose, 6% amino-oligosaccharide
Aqua single dose, first time spray is carried out in tomato virus disease early stage, is total to dispenser three times, every minor tick 7 days, mu water consumption
15L.And 7d, 14d, 21d are investigated after medicine three times, are classified according to related data, disease index is counted, is calculated anti-
Effect, the results are shown in Table 1.
Grade scale is as follows：
0 grade：It is disease-free；
1 grade：Scab heap area accounts for less than the 5% of whole leaf area；
3 grades：Scab heap area accounts for below the 6%-10% of whole leaf area；
5 grades：Scab heap area accounts for below the 11%-20% of whole leaf area；
7 grades：Scab heap area accounts for below the 21%-50% of whole leaf area；
9 grades：Scab heap area accounts for more than the 50% of whole leaf area.
Drug effect computational methods are as follows：
Sick leaf rate (the %)=sick number of sheets/investigation total number of sheets × 100
Disease index=Σ (the sick numbers of sheets at different levels × relative value of series)/(investigation total number of sheets × 9) × 100
Prevention effect (%)=[1- (disease index after disease index × treatment region medicine before blank district medicine)/(blank pair
According to disease index before disease index after area's medicine × treatment region medicine)] × 100.
The reagent agent of table 1 is to tomato virus disease test of pesticide effectiveness result
Field test embodiment two：The field control effectiveness test field of matrine and compound A compositions to Summer squash virus
Between determine
After the composition of different content, different compound A and matrine is re-dubbed 5 kinds of different formulations, in cucurbita pepo disease
Viral disease early stage carries out foliar spray, and every mu is watered 15L, and comparison medicament is 2% aqueous matrine solution, 6% amino-oligosacchride aqua
Single dose, first time spray is carried out in Summer squash virus early stage, is total to dispenser three times, every minor tick 7 days, mu water consumption 15L.
And 7d, 14d, 21d are investigated after medicine three times, standard grading is investigated according to related data, counts disease index, calculated anti-
Effect, the results are shown in Table 2.
Grade scale and drug effect computational methods are same as above.
The reagent agent of table 2 is to Summer squash virus test of pesticide effectiveness result
Field test embodiment three：The field control effectiveness test field of matrine and compound A compositions to color green pepper virosis
Measure
After the composition of different content, different compound A and matrine is re-dubbed 5 kinds of different formulations, in color green pepper virus
Sick early stage carries out foliar spray, and every mu is watered 15L, and comparison medicament is 2% aqueous matrine solution, 6% amino-oligosacchride aqua list
Agent, first time spray is carried out in color green pepper virosis early stage, is total to dispenser three times, every minor tick 7 days, mu water consumption 15L.And point
7d, 14d, 21d are investigated not after medicine three times, are investigated standard grading according to related data, are counted disease index, calculate preventive effect, knot
Fruit is shown in Table 3.
Grade scale and drug effect computational methods are same as above.
The reagent agent of table 3 is to color green pepper virosis test of pesticide effectiveness result
Shown by above field experiment：Matrine and each mixtures of compound A are to tomato, cucurbita pepo, color green pepper virosis
Preventive effect is obviously higher than single matrine and amino-oligosacchride single dose, and preventive effect is above 80% after 21 days after medicine.
Claims (5)
- A kind of 1. composition containing matrine, it is characterised in that said composition active ingredient is matrine and compound A, wherein Compound A is：A1：(1S, 3S)-N '-(4- chlorobenzenes methylene) -1- methyl -2,3,4,9- tetrahydropyridines simultaneously [3,4-b] Yin Diindyl -3- formylhydrazines (VII-6) or A2：(1S, 3S)-N '-(cyclohexylmethylene) -1- methyl -2,3,4,9- tetrahydropyridines simultaneously [3, 4-b] indoles -3- formylhydrazines (VII-6).
- 2. the composition containing matrine as claimed in claim 1, it is characterised in that calculate by weight percentage, matrine accounts for multiple Percentage by weight with composition is 0.05%~5%, compound A account for the percentage by weight of complex composition for 0.1%~ 80%.
- 3. the composition containing matrine as claimed in claim 2, it is characterised in that active ingredient matrine and compound A are accounted for The percentage by weight of total composition is 0.15%~85%.
- 4. the composition containing matrine as claimed in claim 1, it is characterised in that said composition is for preventing and treating fruit tree, vegetable Application in terms of the virosis of dish and field crop.
- 5. the composition containing matrine as claimed in claim 1, it is characterised in that described containing matrine and compound A Composition can be prepared into any one in aqua, wettable powder, suspending agent, water dispersible granules, pulvis.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710914694.3A CN107711856A (en) | 2017-09-30 | 2017-09-30 | A kind of composition containing matrine |
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|---|---|---|---|
| CN201710914694.3A CN107711856A (en) | 2017-09-30 | 2017-09-30 | A kind of composition containing matrine |
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| CN107711856A true CN107711856A (en) | 2018-02-23 |
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| CN201710914694.3A Pending CN107711856A (en) | 2017-09-30 | 2017-09-30 | A kind of composition containing matrine |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110859105A (en) * | 2019-12-14 | 2020-03-06 | 贵州朝鑫生态农业发展有限公司 | Planting method of bee sugar plums |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104744460A (en) * | 2013-12-30 | 2015-07-01 | 南开大学 | B-carboline, dihydro-B-carboline and tetrahydro-B-carboline alkaloid derivative as well as preparation method and application in aspects of plant virus prevention and cure, sterilization and insecticide |
-
2017
- 2017-09-30 CN CN201710914694.3A patent/CN107711856A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104744460A (en) * | 2013-12-30 | 2015-07-01 | 南开大学 | B-carboline, dihydro-B-carboline and tetrahydro-B-carboline alkaloid derivative as well as preparation method and application in aspects of plant virus prevention and cure, sterilization and insecticide |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110859105A (en) * | 2019-12-14 | 2020-03-06 | 贵州朝鑫生态农业发展有限公司 | Planting method of bee sugar plums |
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