CN107709470B - 超亮二聚或多聚染料 - Google Patents
超亮二聚或多聚染料 Download PDFInfo
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- CN107709470B CN107709470B CN201680006600.6A CN201680006600A CN107709470B CN 107709470 B CN107709470 B CN 107709470B CN 201680006600 A CN201680006600 A CN 201680006600A CN 107709470 B CN107709470 B CN 107709470B
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- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
- C09B3/00—Dyes with an anthracene nucleus condensed with one or more carbocyclic rings
- C09B3/14—Perylene derivatives
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- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
- C09B69/00—Dyes not provided for by a single group of this subclass
- C09B69/10—Polymeric dyes; Reaction products of dyes with monomers or with macromolecular compounds
- C09B69/109—Polymeric dyes; Reaction products of dyes with monomers or with macromolecular compounds containing other specific dyes
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
- C09B69/00—Dyes not provided for by a single group of this subclass
- C09B69/10—Polymeric dyes; Reaction products of dyes with monomers or with macromolecular compounds
- C09B69/101—Polymeric dyes; Reaction products of dyes with monomers or with macromolecular compounds containing an anthracene dye
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
- C09B69/00—Dyes not provided for by a single group of this subclass
- C09B69/10—Polymeric dyes; Reaction products of dyes with monomers or with macromolecular compounds
- C09B69/101—Polymeric dyes; Reaction products of dyes with monomers or with macromolecular compounds containing an anthracene dye
- C09B69/102—Polymeric dyes; Reaction products of dyes with monomers or with macromolecular compounds containing an anthracene dye containing a perylene dye
-
- C—CHEMISTRY; METALLURGY
- C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
- C09B—ORGANIC DYES OR CLOSELY-RELATED COMPOUNDS FOR PRODUCING DYES, e.g. PIGMENTS; MORDANTS; LAKES
- C09B69/00—Dyes not provided for by a single group of this subclass
- C09B69/10—Polymeric dyes; Reaction products of dyes with monomers or with macromolecular compounds
- C09B69/103—Polymeric dyes; Reaction products of dyes with monomers or with macromolecular compounds containing a diaryl- or triarylmethane dye
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
- G01N33/582—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances with fluorescent label
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2510/00—Detection of programmed cell death, i.e. apoptosis
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Plural Heterocyclic Compounds (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US201562159771P | 2015-05-11 | 2015-05-11 | |
| US62/159,771 | 2015-05-11 | ||
| PCT/US2016/031831 WO2016183185A1 (en) | 2015-05-11 | 2016-05-11 | Ultra bright dimeric or polymeric dyes |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN107709470A CN107709470A (zh) | 2018-02-16 |
| CN107709470B true CN107709470B (zh) | 2021-01-29 |
Family
ID=57248385
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201680006600.6A Active CN107709470B (zh) | 2015-05-11 | 2016-05-11 | 超亮二聚或多聚染料 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US10865310B2 (enExample) |
| EP (1) | EP3294811B1 (enExample) |
| JP (1) | JP6849599B2 (enExample) |
| KR (1) | KR102765335B1 (enExample) |
| CN (1) | CN107709470B (enExample) |
| WO (1) | WO2016183185A1 (enExample) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP3019559A4 (en) | 2013-08-22 | 2017-04-05 | Sony Corporation | Water soluble fluorescent or colored dyes and methods for their use |
| KR101829159B1 (ko) | 2014-01-16 | 2018-02-13 | 소니 주식회사 | 수용성 형광 또는 유색 염료 |
| WO2016138457A1 (en) | 2015-02-26 | 2016-09-01 | Sony Corporation | Phenylethynylnaphthalene dyes and methods for their use |
| KR102676814B1 (ko) | 2015-02-26 | 2024-06-21 | 소니그룹주식회사 | 접합 그룹을 포함하는 수용성 형광 또는 착색 염료 |
| JP6849599B2 (ja) | 2015-05-11 | 2021-03-24 | ソニー株式会社 | 超明色ダイマーまたはポリマー染料 |
| US11434377B2 (en) | 2016-04-01 | 2022-09-06 | Sony Corporation | Ultra bright dimeric or polymeric dyes with rigid spacing groups |
| KR102530707B1 (ko) * | 2016-04-01 | 2023-05-11 | 소니그룹주식회사 | 초휘도 이량체성 또는 중합체성 염료 |
| KR20180133890A (ko) * | 2016-04-06 | 2018-12-17 | 소니 주식회사 | 스페이싱 링커 그룹을 포함하는 초고명도 이량체성 또는 중합체성 염료 |
| WO2017197014A2 (en) | 2016-05-10 | 2017-11-16 | Sony Corporation | Compositions comprising a polymeric dye and a cyclodextrin and uses thereof |
| WO2017196954A1 (en) | 2016-05-10 | 2017-11-16 | Sony Corporation | Ultra bright polymeric dyes with peptide backbones |
| EP3455300A1 (en) | 2016-05-11 | 2019-03-20 | Sony Corporation | Ultra bright dimeric or polymeric dyes |
| JP7068191B2 (ja) | 2016-06-06 | 2022-05-16 | ソニーグループ株式会社 | 蛍光または有色レポーター基を含むイオン性ポリマー |
| US12018159B2 (en) | 2016-07-29 | 2024-06-25 | Sony Group Corporation | Ultra bright dimeric or polymeric dyes and methods for preparation of the same |
| AU2018282868B2 (en) | 2017-06-16 | 2023-10-19 | Duke University | Resonator networks for improved label detection, computation, analyte sensing, and tunable random number generation |
| JP7551056B2 (ja) | 2017-10-05 | 2024-09-17 | ソニーグループ株式会社 | プログラマブルなポリマー薬物 |
| EP3691689A1 (en) | 2017-10-05 | 2020-08-12 | Sony Corporation | Programmable dendritic drugs |
| CN111836645A (zh) * | 2017-11-16 | 2020-10-27 | 索尼公司 | 可编程的聚合药物 |
| WO2019140301A1 (en) | 2018-01-12 | 2019-07-18 | Sony Corporation | Polymers with rigid spacing groups comprising biologically active compounds |
| US20200360526A1 (en) * | 2018-01-12 | 2020-11-19 | Sony Corporation | Phosphoalkyl polymers comprising biologically active compounds |
| EP4616912A3 (en) | 2018-01-12 | 2025-11-19 | Sony Group Corporation | Phosphoalkyl ribose polymers comprising biologically active compounds |
| KR102742386B1 (ko) * | 2018-03-19 | 2024-12-16 | 소니그룹주식회사 | 형광 신호 향상을 위한 2가 금속의 사용 |
| WO2019182766A1 (en) | 2018-03-21 | 2019-09-26 | Sony Corporation | Polymeric tandem dyes with linker groups |
| WO2019191482A1 (en) | 2018-03-30 | 2019-10-03 | Becton, Dickinson And Company | Water-soluble polymeric dyes having pendant chromophores |
| KR102854332B1 (ko) | 2018-06-27 | 2025-09-03 | 소니그룹주식회사 | 디옥시리보오스를 포함하는 링커 군을 갖는 중합체성 염료 |
| WO2020014634A1 (en) | 2018-07-13 | 2020-01-16 | Sony Corporation | Polymeric dyes having a backbone comprising organophosphate units |
| KR20210152522A (ko) * | 2019-04-11 | 2021-12-15 | 소니그룹주식회사 | 프로그램 가능한 중합체성 약물 |
| EP3952917A1 (en) * | 2019-04-11 | 2022-02-16 | Sony Group Corporation | Programmable polymeric drugs |
| EP3952916A1 (en) * | 2019-04-11 | 2022-02-16 | Sony Group Corporation | Programmable polymeric drugs |
| KR102486779B1 (ko) * | 2019-09-26 | 2023-01-12 | 소니그룹주식회사 | 링커 그룹을 갖는 중합체성 탠덤 염료 |
| WO2021067483A1 (en) | 2019-09-30 | 2021-04-08 | Sony Corporation | Nucleotide probes |
| US20240092820A1 (en) * | 2020-11-25 | 2024-03-21 | Sony Group Corporation | Polymer dyes |
| EP4256078A1 (en) | 2020-12-07 | 2023-10-11 | Sony Group Corporation | Spacing linker group design for brightness enhancement in dimeric or polymeric dyes |
| US12180401B2 (en) | 2021-04-07 | 2024-12-31 | Becton, Dickinson And Company | Water-soluble fluorescent polymeric dyes |
| KR20250023376A (ko) | 2022-06-15 | 2025-02-18 | 소니그룹주식회사 | 스페이싱 링커 그룹을 갖는 중합체 탠덤 염료 |
| WO2023242662A2 (en) | 2022-06-15 | 2023-12-21 | Sony Group Corporation | Polymeric tandem dyes with spacing linker groups |
| WO2025047293A1 (ja) * | 2023-08-30 | 2025-03-06 | ソニーグループ株式会社 | 化合物、検出システムおよび測定装置 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105377994A (zh) * | 2013-08-22 | 2016-03-02 | 索尼公司 | 水溶性荧光染料或有色染料及其使用方法 |
Family Cites Families (98)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4450305A (en) | 1982-10-25 | 1984-05-22 | American Cyanamid Company | Poly(ethyleneoxy)-substituted-9,10-bis(phenylethynyl)anthracenes |
| US4476229A (en) | 1982-11-08 | 1984-10-09 | Abbott Laboratories | Substituted carboxyfluoresceins |
| SU1121931A1 (ru) | 1983-01-10 | 1988-04-15 | Институт Биологической Химии Ан Бсср | Конъюгаты тиреоидных гормонов с альбумином дл выработки антител к тиреоидным гормонам у животных |
| US5268486A (en) | 1986-04-18 | 1993-12-07 | Carnegie-Mellon Unversity | Method for labeling and detecting materials employing arylsulfonate cyanine dyes |
| US5053054A (en) | 1988-09-12 | 1991-10-01 | Ortho Pharmaceutical Corporation | Methods and reagents for staining intracellular components |
| US5318894A (en) | 1990-01-30 | 1994-06-07 | Miles Inc. | Composition, device and method of assaying for peroxidatively active substances |
| US6365730B1 (en) | 1990-06-19 | 2002-04-02 | Gene Shears Pty. Limited | DNA-Armed ribozymes and minizymes |
| JPH04282391A (ja) | 1991-03-08 | 1992-10-07 | Fujisawa Pharmaceut Co Ltd | エタノールアミン誘導体およびその製造法 |
| ATE152831T1 (de) | 1991-09-16 | 1997-05-15 | Molecular Probes Inc | Dimere unsymmetrische cyaninfarbstoffe |
| US5565322A (en) | 1991-11-07 | 1996-10-15 | Nanogen, Inc. | Hybridization of polynucleotides conjugated with chromophores and fluorophores to generate donor-to donor energy transfer system |
| EP0708837B1 (en) | 1993-07-13 | 2006-03-08 | Abbott Laboratories | Fluorescent polymer labeled conjugates and intermediates |
| US6171859B1 (en) | 1994-03-30 | 2001-01-09 | Mitokor | Method of targeting conjugate molecules to mitochondria |
| US6218108B1 (en) | 1997-05-16 | 2001-04-17 | Research Corporation Technologies, Inc. | Nucleoside analogs with polycyclic aromatic groups attached, methods of synthesis and uses therefor |
| DE19717904A1 (de) | 1997-04-23 | 1998-10-29 | Diagnostikforschung Inst | Säurelabile und enzymatisch spaltbare Farbstoffkonstrukte zur Diagnostik mit Nahinfrarotlicht und zur Therapie |
| US6627400B1 (en) | 1999-04-30 | 2003-09-30 | Aclara Biosciences, Inc. | Multiplexed measurement of membrane protein populations |
| US6514700B1 (en) | 1999-04-30 | 2003-02-04 | Aclara Biosciences, Inc. | Nucleic acid detection using degradation of a tagged sequence |
| US6479650B1 (en) | 1999-12-14 | 2002-11-12 | Research Corporation Technologies, Inc. | Fluorescent nucleoside analogs and combinatorial fluorophore arrays comprising same |
| AU2001245643A1 (en) | 2000-03-14 | 2001-09-24 | Genigma Corporation | Biomarkers for the labeling, visual detection and quantification of biomolecules |
| AU8911101A (en) | 2000-09-11 | 2002-03-26 | Univ Columbia | Combinatorial fluorescence energy transfer tags and uses thereof |
| WO2002024815A1 (en) | 2000-09-19 | 2002-03-28 | Li-Cor, Inc. | Cyanine dyes |
| US6448407B1 (en) | 2000-11-01 | 2002-09-10 | Pe Corporation (Ny) | Atropisomers of asymmetric xanthene fluorescent dyes and methods of DNA sequencing and fragment analysis |
| GB2372256A (en) * | 2001-02-14 | 2002-08-21 | Kalibrant Ltd | Detectable entity comprising a plurality of detectable units releasably connected together by stimulus-cleavable linkers for use in fluorescence detection |
| US8323903B2 (en) | 2001-10-12 | 2012-12-04 | Life Technologies Corporation | Antibody complexes and methods for immunolabeling |
| JP3813890B2 (ja) | 2002-03-22 | 2006-08-23 | 富士写真フイルム株式会社 | 3層レジストプロセス用中間層材料組成物及びそれを用いたパターン形成方法 |
| AU2003262833A1 (en) | 2002-08-23 | 2004-03-11 | The Board Of Trustees Of The Leland Stanford Junior University | Fluorescent glycosides and methods for their use |
| WO2004092324A2 (en) | 2002-08-26 | 2004-10-28 | The Regents Of The University Of California | Methods and compositions for detection and analysis of polynucleotides using light harvesting multichromophores |
| US20040138467A1 (en) | 2002-11-26 | 2004-07-15 | French Roger Harquail | Aromatic and aromatic/heteroaromatic molecular structures with controllable electron conducting properties |
| US7759459B2 (en) | 2003-01-10 | 2010-07-20 | Albert Einstein College Of Medicine Of Yeshiva University | Fluorescent assays for protein kinases |
| US7238792B2 (en) | 2003-03-18 | 2007-07-03 | Washington State University Research Foundation | Foldable polymers as probes |
| US7172907B2 (en) | 2003-03-21 | 2007-02-06 | Ge Healthcare Bio-Sciences Corp. | Cyanine dye labelling reagents with meso-substitution |
| AU2003296419A1 (en) | 2003-12-09 | 2005-07-21 | Molecular Probes, Inc. | Pyrenyloxysulfonic acid fluorescent agents |
| WO2006078278A2 (en) | 2004-04-27 | 2006-07-27 | Alnylam Pharmaceuticals, Inc. | Single-stranded and double-stranded oligonucleotides comprising a 2-arylpropyl moiety |
| ES2461858T3 (es) | 2004-08-13 | 2014-05-21 | Epoch Biosciences, Inc. | Colorantes fluorescentes de fosfonato y conjugados |
| US8586718B2 (en) | 2004-09-14 | 2013-11-19 | Applied Biosystems, Llc | Multi-chromophoric quencher constructs for use in high sensitivity energy transfer probes |
| US8153706B2 (en) | 2004-10-25 | 2012-04-10 | Hewlett-Packard Development Company, L.P. | Polymeric colorants having pigment and dye components and corresponding ink compositions |
| EP1655317B1 (en) | 2004-11-09 | 2007-06-13 | Ipagsa Industrial, SL. | Thermally reactive infrared absorption polymers and their use in a heat sensitive lithographic printing plate |
| EP2502946B1 (en) | 2005-01-10 | 2017-10-04 | The Regents of The University of California | Cationic conjugated polymers suitable for strand-specific polynucleiotide detection in homogeneous and solid state assays |
| AU2006223384B2 (en) | 2005-03-09 | 2012-08-02 | Cepheid | Polar dyes |
| US8227621B2 (en) | 2005-06-30 | 2012-07-24 | Li-Cor, Inc. | Cyanine dyes and methods of use |
| WO2007038659A1 (en) * | 2005-09-26 | 2007-04-05 | Invitrogen Corporation | Violet laser excitable dyes and their method of use |
| EP2573833B1 (en) | 2005-12-12 | 2014-04-02 | Basf Se | Organic semiconductors, their manufacture and semiconductor devices comprising them |
| US20070148094A1 (en) | 2005-12-22 | 2007-06-28 | Uzgiris Egidijus E | Polymeric imaging agents and medical imaging methods |
| WO2008021208A2 (en) | 2006-08-12 | 2008-02-21 | Stx Aprilis, Inc. | Sensitizer dyes for photoacid generating systems using short visible wavelengths |
| US8217389B2 (en) | 2006-10-12 | 2012-07-10 | Idemitsu Kosan, Co., Ltd. | Organic thin film transistor device and organic thin film light-emitting transistor |
| EP2064290B1 (en) | 2006-10-27 | 2013-10-09 | Life Technologies Corporation | Fluorogenic ph sensitive dyes and their method of use |
| US8053588B2 (en) | 2007-03-07 | 2011-11-08 | Kabushiki Kaisha Toyota Chuo Kenkyusho | Organosilane compound and organosilica obtained therefrom |
| ES2516827T3 (es) | 2007-04-23 | 2014-10-31 | Deliversir Ltd | Un sistema para entregar agentes terapéuticos a células vivas y núcleos de células |
| US9156865B2 (en) | 2007-04-23 | 2015-10-13 | Deliversir Ltd | System for delivering therapeutic agents into living cells and cells nuclei |
| US9556210B2 (en) | 2007-04-23 | 2017-01-31 | Sabag-Rfa Ltd. | System for delivering therapeutic agents into living cells and cells nuclei |
| WO2008138726A2 (en) | 2007-05-11 | 2008-11-20 | Basf Se | Polymeric dyes |
| EP2014698A1 (en) * | 2007-07-12 | 2009-01-14 | Crystax Pharmaceuticals S.L. | Polymers and their use as fluorescent labels |
| TWI409280B (zh) | 2007-07-31 | 2013-09-21 | American Dye Source Inc | 聚合物染料、塗覆層組合物及熱微影印刷板 |
| GB2456298A (en) | 2008-01-07 | 2009-07-15 | Anthony Ian Newman | Electroluminescent materials comprising oxidation resistant fluorenes |
| ES2613844T3 (es) | 2008-04-21 | 2017-05-26 | Lawrence Livermore National Security, Llc | Ligandos polidentados de alta afinidad selectivos y métodos para producirlos |
| JPWO2010026957A1 (ja) | 2008-09-03 | 2012-02-02 | 国立大学法人富山大学 | 水溶性ロタキサン型蛍光色素および蛍光性有機分子 |
| WO2010055789A1 (ja) * | 2008-11-14 | 2010-05-20 | 独立行政法人科学技術振興機構 | オリゴヌクレオチド誘導体、ラベル化剤及びその利用 |
| US9400273B1 (en) | 2009-12-09 | 2016-07-26 | Life Technologies Corporation | 7-hydroxycoumarin-based cell-tracking reagents |
| WO2011088193A2 (en) | 2010-01-13 | 2011-07-21 | University Of Medicine And Dentistry Of New Jersey | Fluorophore chelated lanthanide luminiscent probes with improved quantum efficiency |
| WO2011120053A1 (en) | 2010-03-26 | 2011-09-29 | Mersana Therapeutics, Inc. | Modified polymers for delivery of polynucleotides, method of manufacture, and methods of use thereof |
| US9995679B2 (en) * | 2010-05-25 | 2018-06-12 | Carnegie Mellon University | Targeted probes of cellular physiology |
| CN102971283A (zh) | 2010-07-08 | 2013-03-13 | 旭硝子株式会社 | 含氟芳香族化合物、有机半导体材料和有机薄膜器件 |
| WO2012080836A2 (en) | 2010-12-13 | 2012-06-21 | Marek Kwiatkowski | Functionalized polymers |
| WO2013012687A2 (en) | 2011-07-15 | 2013-01-24 | Glumetrics, Inc. | Combinations of fluorphores and pyridinium boronic acid quenchers for use in analyte sensors |
| US20130059343A1 (en) | 2011-09-06 | 2013-03-07 | Li-Cor, Inc. | Nucleotide derivatives |
| US9085761B1 (en) * | 2012-06-14 | 2015-07-21 | Affymetrix, Inc. | Methods and compositions for amplification of nucleic acids |
| CA2880290C (en) | 2012-09-12 | 2020-10-27 | Quark Pharmaceuticals, Inc. | Double-stranded oligonucleotide molecules targeting p53 and methods of use thereof |
| US20150258217A1 (en) | 2012-10-04 | 2015-09-17 | The General Hospital Corporation | Methods of Synthesizing and Using Peg-Like Fluorochromes |
| EP2908864B1 (en) | 2012-10-22 | 2019-12-11 | Sabag-Rfa Ltd. | Phosphate compounds for delivering therapeutic agents into living cells and cells nuclei |
| WO2014102803A1 (en) | 2012-12-31 | 2014-07-03 | Yeda Research And Development Co. Ltd. | Molecular sensor and methods of use thereof |
| US9545447B2 (en) | 2013-01-04 | 2017-01-17 | The Texas A&M University System | Polymer-drug systems |
| WO2014159392A1 (en) | 2013-03-14 | 2014-10-02 | Dana-Farber Cancer Institute, Inc. | Bromodomain binding reagents and uses thereof |
| WO2014147642A1 (en) | 2013-03-19 | 2014-09-25 | Council Of Scientific & Industrial Research | Substituted fluoranthene-7-carbonitriles as fluorescent dyes for cell imaging applications |
| US10406246B2 (en) | 2013-10-17 | 2019-09-10 | Deutsches Kresbsforschungszentrum | Double-labeled probe for molecular imaging and use thereof |
| WO2015068697A1 (ja) | 2013-11-11 | 2015-05-14 | オリンパスメディカルシステムズ株式会社 | 処置システム |
| US9150782B2 (en) | 2013-12-06 | 2015-10-06 | Monosol, Llc | Fluorescent tracer for water-soluble films, related methods, and related articles |
| KR101829159B1 (ko) | 2014-01-16 | 2018-02-13 | 소니 주식회사 | 수용성 형광 또는 유색 염료 |
| JP6374172B2 (ja) | 2014-01-31 | 2018-08-15 | 富士フイルム株式会社 | 着色組成物、およびこれを用いた硬化膜、カラーフィルタ、パターン形成方法、カラーフィルタの製造方法、固体撮像素子、画像表示装置ならびに染料多量体 |
| US20170326233A1 (en) | 2014-11-14 | 2017-11-16 | Angiochem Inc. | Conjugates including an antibody moiety, a polypeptide that traverses the blood-brain barrier, and a cytotoxin |
| KR102676814B1 (ko) | 2015-02-26 | 2024-06-21 | 소니그룹주식회사 | 접합 그룹을 포함하는 수용성 형광 또는 착색 염료 |
| WO2016138457A1 (en) | 2015-02-26 | 2016-09-01 | Sony Corporation | Phenylethynylnaphthalene dyes and methods for their use |
| ES2925694T3 (es) | 2015-03-12 | 2022-10-19 | Becton Dickinson Co | Colorantes poliméricos de BODIPY y métodos de uso de los mismos |
| JP6849599B2 (ja) | 2015-05-11 | 2021-03-24 | ソニー株式会社 | 超明色ダイマーまたはポリマー染料 |
| US9670318B2 (en) | 2015-05-28 | 2017-06-06 | Miltenyi Biotec Gmbh | Bright fluorochromes based on multimerization of fluorescent dyes |
| US9913992B2 (en) | 2015-12-22 | 2018-03-13 | Colgate-Palmolive Company | Oral treatment device |
| KR102530707B1 (ko) | 2016-04-01 | 2023-05-11 | 소니그룹주식회사 | 초휘도 이량체성 또는 중합체성 염료 |
| US11434377B2 (en) | 2016-04-01 | 2022-09-06 | Sony Corporation | Ultra bright dimeric or polymeric dyes with rigid spacing groups |
| KR20180133890A (ko) | 2016-04-06 | 2018-12-17 | 소니 주식회사 | 스페이싱 링커 그룹을 포함하는 초고명도 이량체성 또는 중합체성 염료 |
| WO2017197014A2 (en) * | 2016-05-10 | 2017-11-16 | Sony Corporation | Compositions comprising a polymeric dye and a cyclodextrin and uses thereof |
| WO2017196954A1 (en) | 2016-05-10 | 2017-11-16 | Sony Corporation | Ultra bright polymeric dyes with peptide backbones |
| EP3455300A1 (en) | 2016-05-11 | 2019-03-20 | Sony Corporation | Ultra bright dimeric or polymeric dyes |
| JP7068191B2 (ja) | 2016-06-06 | 2022-05-16 | ソニーグループ株式会社 | 蛍光または有色レポーター基を含むイオン性ポリマー |
| US12018159B2 (en) | 2016-07-29 | 2024-06-25 | Sony Group Corporation | Ultra bright dimeric or polymeric dyes and methods for preparation of the same |
| GB2554666B (en) | 2016-09-30 | 2019-12-18 | Sumitomo Chemical Co | Composite Particle |
| EP3691689A1 (en) | 2017-10-05 | 2020-08-12 | Sony Corporation | Programmable dendritic drugs |
| JP7551056B2 (ja) | 2017-10-05 | 2024-09-17 | ソニーグループ株式会社 | プログラマブルなポリマー薬物 |
| EP3952916A1 (en) | 2019-04-11 | 2022-02-16 | Sony Group Corporation | Programmable polymeric drugs |
| EP3952917A1 (en) | 2019-04-11 | 2022-02-16 | Sony Group Corporation | Programmable polymeric drugs |
| KR20210152522A (ko) | 2019-04-11 | 2021-12-15 | 소니그룹주식회사 | 프로그램 가능한 중합체성 약물 |
-
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| CN105377994A (zh) * | 2013-08-22 | 2016-03-02 | 索尼公司 | 水溶性荧光染料或有色染料及其使用方法 |
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| JP2018515628A (ja) | 2018-06-14 |
| US10865310B2 (en) | 2020-12-15 |
| CN107709470A (zh) | 2018-02-16 |
| EP3294811B1 (en) | 2024-02-28 |
| EP3294811A1 (en) | 2018-03-21 |
| KR20180005650A (ko) | 2018-01-16 |
| JP6849599B2 (ja) | 2021-03-24 |
| EP3294811A4 (en) | 2019-02-20 |
| KR102765335B1 (ko) | 2025-02-13 |
| US20180079909A1 (en) | 2018-03-22 |
| WO2016183185A1 (en) | 2016-11-17 |
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