CN107708685B - 含有降胭脂树素的、用于保护视网膜色素上皮细胞的组合物 - Google Patents

含有降胭脂树素的、用于保护视网膜色素上皮细胞的组合物 Download PDF

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Publication number
CN107708685B
CN107708685B CN201680037407.9A CN201680037407A CN107708685B CN 107708685 B CN107708685 B CN 107708685B CN 201680037407 A CN201680037407 A CN 201680037407A CN 107708685 B CN107708685 B CN 107708685B
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norbixin
composition
composition according
body weight
mammal
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CN107708685A (zh
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勒内·拉丰
斯坦尼斯拉斯·韦耶
乔斯-阿兰·撒海尔
瓦莱丽·封丹
皮埃尔-保尔·爱琳娜
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Sorbonne Universite
Biophytis SA
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Universite Pierre et Marie Curie
Biophytis SA
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/20—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids
    • A61K31/202—Carboxylic acids, e.g. valproic acid having a carboxyl group bound to a chain of seven or more carbon atoms, e.g. stearic, palmitic, arachidic acids having three or more double bonds, e.g. linolenic
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES, NOT OTHERWISE PROVIDED FOR; PREPARATION OR TREATMENT THEREOF
    • A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105—Plant extracts, their artificial duplicates or their derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A61K31/355—Tocopherols, e.g. vitamin E
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A61K31/375—Ascorbic acid, i.e. vitamin C; Salts thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/24—Heavy metals; Compounds thereof
    • A61K33/30—Zinc; Compounds thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Engineering & Computer Science (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medical Informatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Microbiology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Inorganic Chemistry (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Dermatology (AREA)
  • Physiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Medicinal Preparation (AREA)
CN201680037407.9A 2015-04-30 2016-04-28 含有降胭脂树素的、用于保护视网膜色素上皮细胞的组合物 Active CN107708685B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR1553957 2015-04-30
FR1553957A FR3035589B1 (fr) 2015-04-30 2015-04-30 Composition pour la protection des cellules de l'epithelium pigmentaire retinien
PCT/FR2016/051001 WO2016174360A1 (fr) 2015-04-30 2016-04-28 Composition contenant de la norbixine pour la protection des cellules de l'epithelium pigmentaire retinien

Publications (2)

Publication Number Publication Date
CN107708685A CN107708685A (zh) 2018-02-16
CN107708685B true CN107708685B (zh) 2021-09-21

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CN201680037407.9A Active CN107708685B (zh) 2015-04-30 2016-04-28 含有降胭脂树素的、用于保护视网膜色素上皮细胞的组合物

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US (1) US10314804B2 (enExample)
EP (1) EP3288551B1 (enExample)
JP (1) JP6660401B2 (enExample)
KR (1) KR102575312B1 (enExample)
CN (1) CN107708685B (enExample)
AU (1) AU2016256637A1 (enExample)
BR (1) BR112017023264A2 (enExample)
CA (1) CA2984405C (enExample)
ES (1) ES2752061T3 (enExample)
FR (1) FR3035589B1 (enExample)
IL (1) IL255276A0 (enExample)
MX (1) MX376021B (enExample)
PL (1) PL3288551T3 (enExample)
RU (1) RU2715889C2 (enExample)
WO (1) WO2016174360A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR3078252B1 (fr) * 2018-02-28 2020-08-14 Biophytis Phytoecdysones pour leur utilisation dans la prevention de la perte de force musculaire lors d’une immobilisation
CA3098868A1 (en) 2018-05-03 2019-11-07 L.E.A.F. Holdings Group Llc Carotenoid compositions and uses thereof
KR20200134935A (ko) 2019-05-24 2020-12-02 (주)비지엔케어 커큐민을 유효성분으로 포함하는 인간 망막색소상피세포 증식 개선용 약학 조성물
EP4054637A4 (en) * 2019-11-06 2023-12-20 L.E.A.F Holdings Group LLC CAROTINOID COMPOSITIONS AND USES THEREOF
FR3105790B1 (fr) * 2019-12-26 2022-01-14 Biophytis Composés chimiques ciblant l’œil et leur utilisation dans le traitement de maladies oculaires
KR20210008884A (ko) 2021-01-08 2021-01-25 (주)비지엔케어 커큐민을 유효성분으로 포함하는 인간 망막색소상피세포 증식 개선용 조성물 및 기능성 식품 조성물
TWI894483B (zh) * 2022-08-24 2025-08-21 鼎赫生物科技股份有限公司 一種組合物用於治療眼睛疾病之醫藥品用途

Family Cites Families (10)

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Publication number Priority date Publication date Assignee Title
FR1154172A (fr) 1955-07-05 1958-04-03 Rollei Werke Franke Heidecke étui de protection pour appareils photographiques
WO2001085183A2 (en) * 2000-05-08 2001-11-15 N.V. Nutricia Preparation for the prevention and treatment of ocular disorders
CA2528718A1 (en) * 2003-06-20 2004-12-29 Alcon, Inc. Treatment of amd with combination of ingredients
US7887847B2 (en) * 2004-05-08 2011-02-15 Paul Jr Edward L Nutritional supplement for treatment of ocular diseases
EP1814540A2 (en) * 2004-11-16 2007-08-08 Nu-Tein Co., Inc. Compositions useful to treat ocular neovascular diseases and macular degeneration
JP2008179632A (ja) * 2006-12-29 2008-08-07 Fuji Chem Ind Co Ltd 抗酸化剤
JP5550854B2 (ja) * 2009-06-10 2014-07-16 理研ビタミン株式会社 一重項酸素消去剤
FR2947173B1 (fr) 2009-06-25 2012-01-27 Inst Biophytis Composition alimentaire destinee a la protection solaire
JP2012097003A (ja) * 2010-10-29 2012-05-24 Gifu City ビキシン誘導体及び細胞保護剤
FR2975008B1 (fr) * 2011-05-13 2014-03-07 Inst Biophytis Utilisation de composes et composition pour le traitement de la degenerescence maculaire liee a l'age (dmla)

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
ValeÂrie Fontaine等.Norbixin Protects Retinal Pigmented Epithelium Cells and Photoreceptors against A2E-Mediated Phototoxicity In Vitro and In Vivo.《PLOS ONE》.2016,1-25. *
人视网膜色素上皮细胞凋亡的研究综述;王丽丽;《健康必读》;20130331;第12卷(第3期);第534页 *

Also Published As

Publication number Publication date
CA2984405C (fr) 2024-01-23
IL255276A0 (en) 2017-12-31
ES2752061T3 (es) 2020-04-02
PL3288551T3 (pl) 2020-04-30
CA2984405A1 (fr) 2016-11-03
JP6660401B2 (ja) 2020-03-11
FR3035589A1 (fr) 2016-11-04
JP2018518460A (ja) 2018-07-12
KR102575312B1 (ko) 2023-09-06
BR112017023264A2 (pt) 2018-08-07
RU2017141462A (ru) 2019-05-31
US20180289651A1 (en) 2018-10-11
MX2017013918A (es) 2018-04-24
AU2016256637A1 (en) 2017-12-14
EP3288551A1 (fr) 2018-03-07
US10314804B2 (en) 2019-06-11
RU2715889C2 (ru) 2020-03-04
EP3288551B1 (fr) 2019-07-31
WO2016174360A9 (fr) 2017-11-16
RU2017141462A3 (enExample) 2019-09-12
CN107708685A (zh) 2018-02-16
FR3035589B1 (fr) 2019-12-13
WO2016174360A1 (fr) 2016-11-03
KR20180011777A (ko) 2018-02-02
MX376021B (es) 2025-03-07

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