CN107708681A - 含有双醋瑞因的制剂及使用其降低尿酸血液水平的方法 - Google Patents
含有双醋瑞因的制剂及使用其降低尿酸血液水平的方法 Download PDFInfo
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- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 description 1
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 description 1
- 238000007427 paired t-test Methods 0.000 description 1
- 230000035790 physiological processes and functions Effects 0.000 description 1
- 230000000291 postprandial effect Effects 0.000 description 1
- 230000009103 reabsorption Effects 0.000 description 1
- 230000002040 relaxant effect Effects 0.000 description 1
- 238000005070 sampling Methods 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 230000019491 signal transduction Effects 0.000 description 1
- RMAQACBXLXPBSY-UHFFFAOYSA-N silicic acid Chemical compound O[Si](O)(O)O RMAQACBXLXPBSY-UHFFFAOYSA-N 0.000 description 1
- 235000012239 silicon dioxide Nutrition 0.000 description 1
- 159000000000 sodium salts Chemical class 0.000 description 1
- 229920003109 sodium starch glycolate Polymers 0.000 description 1
- 239000008109 sodium starch glycolate Substances 0.000 description 1
- 229940079832 sodium starch glycolate Drugs 0.000 description 1
- 238000007619 statistical method Methods 0.000 description 1
- 239000008117 stearic acid Substances 0.000 description 1
- 230000001629 suppression Effects 0.000 description 1
- 238000013268 sustained release Methods 0.000 description 1
- 239000012730 sustained-release form Substances 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 239000000454 talc Substances 0.000 description 1
- 235000012222 talc Nutrition 0.000 description 1
- 229910052623 talc Inorganic materials 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 229940124597 therapeutic agent Drugs 0.000 description 1
- 235000010487 tragacanth Nutrition 0.000 description 1
- 239000000196 tragacanth Substances 0.000 description 1
- 229940116362 tragacanth Drugs 0.000 description 1
- 238000001890 transfection Methods 0.000 description 1
- 238000003146 transient transfection Methods 0.000 description 1
- 208000001072 type 2 diabetes mellitus Diseases 0.000 description 1
- 229940005267 urate oxidase Drugs 0.000 description 1
- 108010078530 urate transporter Proteins 0.000 description 1
- 230000003424 uricosuric effect Effects 0.000 description 1
- 230000002747 voluntary effect Effects 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
- 239000003064 xanthine oxidase inhibitor Substances 0.000 description 1
- 239000011701 zinc Substances 0.000 description 1
- 229910052725 zinc Inorganic materials 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
- A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/222—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having aromatic groups, e.g. dipivefrine, ibopamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Emergency Medicine (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/US2015/026678 WO2016171656A1 (fr) | 2015-04-20 | 2015-04-20 | Préparations à base de diacéréine et procédés de réduction des taux d'acide urique sanguins grâce à l'utilisation de cette dernière |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107708681A true CN107708681A (zh) | 2018-02-16 |
Family
ID=57143313
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201580081063.7A Pending CN107708681A (zh) | 2015-04-20 | 2015-04-20 | 含有双醋瑞因的制剂及使用其降低尿酸血液水平的方法 |
Country Status (12)
| Country | Link |
|---|---|
| EP (1) | EP3285754A4 (fr) |
| JP (1) | JP2018513203A (fr) |
| KR (1) | KR20180013880A (fr) |
| CN (1) | CN107708681A (fr) |
| AU (1) | AU2015392441A1 (fr) |
| BR (1) | BR112017022509A2 (fr) |
| CA (1) | CA2983394A1 (fr) |
| CO (1) | CO2017011722A2 (fr) |
| IL (1) | IL255073A0 (fr) |
| MX (1) | MX2017013489A (fr) |
| RU (1) | RU2690372C2 (fr) |
| WO (1) | WO2016171656A1 (fr) |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100285114A1 (en) * | 2007-09-27 | 2010-11-11 | Rahul Dabre | Pharmaceutical compositions of rhein or diacerein |
| CN103037849A (zh) * | 2010-06-22 | 2013-04-10 | 安成国际药业股份有限公司 | 具有减少的食物效应的控释组合物 |
| CN103429236A (zh) * | 2011-03-11 | 2013-12-04 | 安成生物科技股份有限公司 | 治疗高尿酸血症和与高尿酸血症相关的代谢性病症的方法和组合物 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH06316517A (ja) * | 1993-02-22 | 1994-11-15 | Grelan Pharmaceut Co Ltd | 放出制御製剤 |
| KR20070058540A (ko) * | 2004-10-01 | 2007-06-08 | 니폰 조키 세야쿠 가부시키가이샤 | 고형 의약제제 |
| EP2167048B1 (fr) * | 2007-05-30 | 2016-10-26 | Wockhardt Limited | Nouvelle forme posologique de comprimé |
| CA2926563A1 (fr) * | 2007-09-27 | 2009-04-02 | Wockhardt Research Centre | Compositions pharmaceutiques de rheine ou de diacereine |
| WO2009048940A2 (fr) * | 2007-10-08 | 2009-04-16 | Dr. Reddy's Laboratories Ltd. | Formulations pharmaceutiques de diacéréine |
| TWI473610B (zh) * | 2008-10-28 | 2015-02-21 | Twi Biotechnology Inc | 包含雙醋瑞因（ｄｉａｃｅｒｅｉｎ）之醫藥組合物 |
| KR101190708B1 (ko) * | 2010-03-12 | 2012-10-12 | 주식회사 대웅제약 | 모사프리드 또는 이의 염을 포함하는 서방형 약학 조성물 |
| UA112632C2 (uk) * | 2010-06-16 | 2016-10-10 | Такеда Фармасьютикалз Ю.Ес.Ей., Інк. | Дозована форма з модифікованим вивільненням фебуксостату (варіанти) |
-
2015
- 2015-04-20 EP EP15890063.9A patent/EP3285754A4/fr not_active Withdrawn
- 2015-04-20 BR BR112017022509A patent/BR112017022509A2/pt not_active Application Discontinuation
- 2015-04-20 KR KR1020177032849A patent/KR20180013880A/ko unknown
- 2015-04-20 AU AU2015392441A patent/AU2015392441A1/en not_active Abandoned
- 2015-04-20 RU RU2017140079A patent/RU2690372C2/ru active
- 2015-04-20 CN CN201580081063.7A patent/CN107708681A/zh active Pending
- 2015-04-20 MX MX2017013489A patent/MX2017013489A/es unknown
- 2015-04-20 WO PCT/US2015/026678 patent/WO2016171656A1/fr active Application Filing
- 2015-04-20 JP JP2017555702A patent/JP2018513203A/ja active Pending
- 2015-04-20 CA CA2983394A patent/CA2983394A1/fr not_active Abandoned
-
2017
- 2017-10-16 IL IL255073A patent/IL255073A0/en unknown
- 2017-11-17 CO CONC2017/0011722A patent/CO2017011722A2/es unknown
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100285114A1 (en) * | 2007-09-27 | 2010-11-11 | Rahul Dabre | Pharmaceutical compositions of rhein or diacerein |
| CN103037849A (zh) * | 2010-06-22 | 2013-04-10 | 安成国际药业股份有限公司 | 具有减少的食物效应的控释组合物 |
| CN103429236A (zh) * | 2011-03-11 | 2013-12-04 | 安成生物科技股份有限公司 | 治疗高尿酸血症和与高尿酸血症相关的代谢性病症的方法和组合物 |
Also Published As
| Publication number | Publication date |
|---|---|
| IL255073A0 (en) | 2017-12-31 |
| RU2017140079A3 (fr) | 2019-05-20 |
| EP3285754A1 (fr) | 2018-02-28 |
| EP3285754A4 (fr) | 2018-12-19 |
| AU2015392441A1 (en) | 2017-11-09 |
| WO2016171656A1 (fr) | 2016-10-27 |
| CA2983394A1 (fr) | 2016-10-27 |
| BR112017022509A2 (pt) | 2018-07-17 |
| JP2018513203A (ja) | 2018-05-24 |
| CO2017011722A2 (es) | 2018-04-19 |
| RU2690372C2 (ru) | 2019-06-03 |
| MX2017013489A (es) | 2018-05-22 |
| RU2017140079A (ru) | 2019-05-20 |
| KR20180013880A (ko) | 2018-02-07 |
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