EP3285754A4 - Préparations à base de diacéréine et procédés de réduction des taux d'acide urique sanguins grâce à l'utilisation de cette dernière - Google Patents
Préparations à base de diacéréine et procédés de réduction des taux d'acide urique sanguins grâce à l'utilisation de cette dernière Download PDFInfo
- Publication number
- EP3285754A4 EP3285754A4 EP15890063.9A EP15890063A EP3285754A4 EP 3285754 A4 EP3285754 A4 EP 3285754A4 EP 15890063 A EP15890063 A EP 15890063A EP 3285754 A4 EP3285754 A4 EP 3285754A4
- Authority
- EP
- European Patent Office
- Prior art keywords
- methods
- same
- uric acid
- formulations containing
- blood levels
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- TYNLGDBUJLVSMA-UHFFFAOYSA-N 4,5-diacetyloxy-9,10-dioxo-2-anthracenecarboxylic acid Chemical compound O=C1C2=CC(C(O)=O)=CC(OC(C)=O)=C2C(=O)C2=C1C=CC=C2OC(=O)C TYNLGDBUJLVSMA-UHFFFAOYSA-N 0.000 title 1
- LEHOTFFKMJEONL-UHFFFAOYSA-N Uric Acid Chemical compound N1C(=O)NC(=O)C2=C1NC(=O)N2 LEHOTFFKMJEONL-UHFFFAOYSA-N 0.000 title 1
- TVWHNULVHGKJHS-UHFFFAOYSA-N Uric acid Natural products N1C(=O)NC(=O)C2NC(=O)NC21 TVWHNULVHGKJHS-UHFFFAOYSA-N 0.000 title 1
- 230000036765 blood level Effects 0.000 title 1
- 229960004590 diacerein Drugs 0.000 title 1
- 238000009472 formulation Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
- 229940116269 uric acid Drugs 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/192—Carboxylic acids, e.g. valproic acid having aromatic groups, e.g. sulindac, 2-aryl-propionic acids, ethacrynic acid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
- A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/12—Ketones
- A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
- A61K31/22—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin
- A61K31/222—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids of acyclic acids, e.g. pravastatin with compounds having aromatic groups, e.g. dipivefrine, ibopamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Emergency Medicine (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/US2015/026678 WO2016171656A1 (fr) | 2015-04-20 | 2015-04-20 | Préparations à base de diacéréine et procédés de réduction des taux d'acide urique sanguins grâce à l'utilisation de cette dernière |
Publications (2)
Publication Number | Publication Date |
---|---|
EP3285754A1 EP3285754A1 (fr) | 2018-02-28 |
EP3285754A4 true EP3285754A4 (fr) | 2018-12-19 |
Family
ID=57143313
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
EP15890063.9A Withdrawn EP3285754A4 (fr) | 2015-04-20 | 2015-04-20 | Préparations à base de diacéréine et procédés de réduction des taux d'acide urique sanguins grâce à l'utilisation de cette dernière |
Country Status (12)
Country | Link |
---|---|
EP (1) | EP3285754A4 (fr) |
JP (1) | JP2018513203A (fr) |
KR (1) | KR20180013880A (fr) |
CN (1) | CN107708681A (fr) |
AU (1) | AU2015392441A1 (fr) |
BR (1) | BR112017022509A2 (fr) |
CA (1) | CA2983394A1 (fr) |
CO (1) | CO2017011722A2 (fr) |
IL (1) | IL255073A0 (fr) |
MX (1) | MX2017013489A (fr) |
RU (1) | RU2690372C2 (fr) |
WO (1) | WO2016171656A1 (fr) |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2008146178A2 (fr) * | 2007-05-30 | 2008-12-04 | Wockhardt Research Centre | Nouvelle forme posologique de comprimé |
WO2009040702A2 (fr) * | 2007-09-27 | 2009-04-02 | Wockhardt Research Centre | Compositions pharmaceutiques de rhéine ou de diacéréine |
WO2009048940A2 (fr) * | 2007-10-08 | 2009-04-16 | Dr. Reddy's Laboratories Ltd. | Formulations pharmaceutiques de diacéréine |
EP2349289A1 (fr) * | 2008-10-28 | 2011-08-03 | TWI Biotechnology, Inc. | Compositions pharmaceutiques contenant de la diacéréine |
US20110311594A1 (en) * | 2010-06-22 | 2011-12-22 | Shou-Chiung Chen | Controlled release compositions with reduced food effect |
US20120232044A1 (en) * | 2011-03-11 | 2012-09-13 | Twi Biotechnology, Inc. | Methods and compositions for treating hyperuricemia and metabolic disorders associated with hyperuricemia |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH06316517A (ja) * | 1993-02-22 | 1994-11-15 | Grelan Pharmaceut Co Ltd | 放出制御製剤 |
EP1795207A1 (fr) * | 2004-10-01 | 2007-06-13 | Nippon Zoki Pharmaceutical Co. Ltd. | Préparation pharmaceutique solide |
US20100285114A1 (en) * | 2007-09-27 | 2010-11-11 | Rahul Dabre | Pharmaceutical compositions of rhein or diacerein |
KR101190708B1 (ko) * | 2010-03-12 | 2012-10-12 | 주식회사 대웅제약 | 모사프리드 또는 이의 염을 포함하는 서방형 약학 조성물 |
JP5865904B2 (ja) * | 2010-06-16 | 2016-02-17 | タケダ ファーマシューティカルズ ユー.エス.エー. インコーポレイティド | キサンチンオキシドレダクターゼ阻害剤またはキサンチンオキシダーゼ阻害剤の新規の調節放出剤形 |
-
2015
- 2015-04-20 CA CA2983394A patent/CA2983394A1/fr not_active Abandoned
- 2015-04-20 CN CN201580081063.7A patent/CN107708681A/zh active Pending
- 2015-04-20 EP EP15890063.9A patent/EP3285754A4/fr not_active Withdrawn
- 2015-04-20 RU RU2017140079A patent/RU2690372C2/ru active
- 2015-04-20 JP JP2017555702A patent/JP2018513203A/ja active Pending
- 2015-04-20 WO PCT/US2015/026678 patent/WO2016171656A1/fr active Application Filing
- 2015-04-20 KR KR1020177032849A patent/KR20180013880A/ko unknown
- 2015-04-20 MX MX2017013489A patent/MX2017013489A/es unknown
- 2015-04-20 BR BR112017022509A patent/BR112017022509A2/pt not_active Application Discontinuation
- 2015-04-20 AU AU2015392441A patent/AU2015392441A1/en not_active Abandoned
-
2017
- 2017-10-16 IL IL255073A patent/IL255073A0/en unknown
- 2017-11-17 CO CONC2017/0011722A patent/CO2017011722A2/es unknown
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2008146178A2 (fr) * | 2007-05-30 | 2008-12-04 | Wockhardt Research Centre | Nouvelle forme posologique de comprimé |
WO2009040702A2 (fr) * | 2007-09-27 | 2009-04-02 | Wockhardt Research Centre | Compositions pharmaceutiques de rhéine ou de diacéréine |
WO2009048940A2 (fr) * | 2007-10-08 | 2009-04-16 | Dr. Reddy's Laboratories Ltd. | Formulations pharmaceutiques de diacéréine |
EP2349289A1 (fr) * | 2008-10-28 | 2011-08-03 | TWI Biotechnology, Inc. | Compositions pharmaceutiques contenant de la diacéréine |
US20110311594A1 (en) * | 2010-06-22 | 2011-12-22 | Shou-Chiung Chen | Controlled release compositions with reduced food effect |
US20120232044A1 (en) * | 2011-03-11 | 2012-09-13 | Twi Biotechnology, Inc. | Methods and compositions for treating hyperuricemia and metabolic disorders associated with hyperuricemia |
Non-Patent Citations (1)
Title |
---|
See also references of WO2016171656A1 * |
Also Published As
Publication number | Publication date |
---|---|
CA2983394A1 (fr) | 2016-10-27 |
EP3285754A1 (fr) | 2018-02-28 |
CO2017011722A2 (es) | 2018-04-19 |
MX2017013489A (es) | 2018-05-22 |
JP2018513203A (ja) | 2018-05-24 |
RU2017140079A (ru) | 2019-05-20 |
BR112017022509A2 (pt) | 2018-07-17 |
WO2016171656A1 (fr) | 2016-10-27 |
RU2017140079A3 (fr) | 2019-05-20 |
KR20180013880A (ko) | 2018-02-07 |
RU2690372C2 (ru) | 2019-06-03 |
CN107708681A (zh) | 2018-02-16 |
IL255073A0 (en) | 2017-12-31 |
AU2015392441A1 (en) | 2017-11-09 |
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Legal Events
Date | Code | Title | Description |
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PUAI | Public reference made under article 153(3) epc to a published international application that has entered the european phase |
Free format text: ORIGINAL CODE: 0009012 |
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17P | Request for examination filed |
Effective date: 20171114 |
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AK | Designated contracting states |
Kind code of ref document: A1 Designated state(s): AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC MK MT NL NO PL PT RO RS SE SI SK SM TR |
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AX | Request for extension of the european patent |
Extension state: BA ME |
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DAV | Request for validation of the european patent (deleted) | ||
DAX | Request for extension of the european patent (deleted) | ||
A4 | Supplementary search report drawn up and despatched |
Effective date: 20181120 |
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RIC1 | Information provided on ipc code assigned before grant |
Ipc: A61K 31/192 20060101AFI20181114BHEP Ipc: A61K 9/20 20060101ALI20181114BHEP |
|
RIC1 | Information provided on ipc code assigned before grant |
Ipc: A61K 9/20 20060101ALI20191024BHEP Ipc: A61K 31/192 20060101AFI20191024BHEP |
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GRAP | Despatch of communication of intention to grant a patent |
Free format text: ORIGINAL CODE: EPIDOSNIGR1 |
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INTG | Intention to grant announced |
Effective date: 20191203 |
|
RIN1 | Information on inventor provided before grant (corrected) |
Inventor name: BROWN III, CARL OSCAR Inventor name: CHEN, CHI-KUANG Inventor name: LU, WEI-SHU Inventor name: LIM, HANPIN Inventor name: CHUNG, TIEN-KUEN |
|
STAA | Information on the status of an ep patent application or granted ep patent |
Free format text: STATUS: THE APPLICATION IS DEEMED TO BE WITHDRAWN |
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18D | Application deemed to be withdrawn |
Effective date: 20200603 |