CN107693833A - A kind of dispel scar moist dressing and preparation method containing bioactivity glass - Google Patents

A kind of dispel scar moist dressing and preparation method containing bioactivity glass Download PDF

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Publication number
CN107693833A
CN107693833A CN201710968187.8A CN201710968187A CN107693833A CN 107693833 A CN107693833 A CN 107693833A CN 201710968187 A CN201710968187 A CN 201710968187A CN 107693833 A CN107693833 A CN 107693833A
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China
Prior art keywords
parts
bioactivity glass
chitosan
scar
vaseline
Prior art date
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Pending
Application number
CN201710968187.8A
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Chinese (zh)
Inventor
朱礼飞
张劲松
李保芝
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Zhangjiagang Blue Zhi Biological Technology Co Ltd
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Zhangjiagang Blue Zhi Biological Technology Co Ltd
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Priority to CN201710968187.8A priority Critical patent/CN107693833A/en
Publication of CN107693833A publication Critical patent/CN107693833A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/20Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing organic materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/18Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing inorganic materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/28Polysaccharides or their derivatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/34Oils, fats, waxes or natural resins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42Use of materials characterised by their function or physical properties
    • A61L15/44Medicaments
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/10Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
    • A61L2300/112Phosphorus-containing compounds, e.g. phosphates, phosphonates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/20Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
    • A61L2300/23Carbohydrates
    • A61L2300/232Monosaccharides, disaccharides, polysaccharides, lipopolysaccharides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412Tissue-regenerating or healing or proliferative agents

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Materials Engineering (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Inorganic Chemistry (AREA)
  • Cosmetics (AREA)
  • Materials For Medical Uses (AREA)

Abstract

A kind of dispel scar moist dressing and preparation method containing bioactivity glass, it is related to a kind of improvement of medical functions apparatus, and in particular to a kind of dispel scar moist dressing and preparation method containing bioactivity glass.It is using vaseline, atoleine as paste host material, is soaked by gauze or non-woven fabric plate under 75 105 degrees Celsius and dries shaping, bioactivity glass and chitosan are prepared for main functional component, and it is made up of the composition of raw materials of following parts by weight:Vaseline:70 parts, atoleine:10 parts, bioactivity glass:12 parts, medical glycerine:2 parts, chitosan:0.7 part, appropriate meche.It can effectively reduce dressing caused by scar, such as the promotion healing of the caesarean operation scar surface of a wound, by bioactivity glass and the anti-inflammatory of chitosan, promote healing function, reduce inflammation and produce, long-acting bacteriostatic, wound healing, particularly effective prevention of scar generation.

Description

A kind of dispel scar moist dressing and preparation method containing bioactivity glass
Technical field
The present invention relates to a kind of improvement of medical functions apparatus, and in particular to a kind of scar of dispelling containing bioactivity glass is wet Property dressing and preparation method.
Background technology
Bioactivity glass be one kind body tissue can be repaired, substituted and be regenerated, have can make tissue and material Between formed bonding action material.The catabolite of bioactivity glass can promote the generation of growth factor, promote cell Procreation, strengthen Gegenbaur's cell gene expression and bone tissue growth.Being so far uniquely can either be with bone tissue bonding With reference to, while the bioartificial materials that and can is connected with soft tissue.Bioactivity glass(Bioactiveglass, BAG), it It is the silicate glass being made up of bases such as SiO2, Na2O, CaO and P2O5.
Bioactivity glass and the most significant feature of glass ceramics are that surface appearance dynamically becomes with the time after being implanted into human body Change, surface forms carbonated hydroxyapatite (HCA) layer of bioactivity, and bonded interface is provided for tissue.Most bioactivity Glass is A class bioactive materials, existing ostosis(osteoproductive), there is bone guided again (osteoconductive)Effect, there is good associativity with bone and soft tissue, BAG is considered as that can be applicable to reparation neck The good biological material in domain.The purposes of such a prosthetic material is not only extremely wide, and in the professional product of various fields On have irreplaceable magical effect, as wrinkle, empyrosis, canker sore, intestine gastric ulcer, skin are removed in skin nursing, whitening Bonding fester, killed fungi, bone repair, soft tissue and bone tissue etc., it is believed that its appearance will be that human health makes Zhuo More contribute.In addition, BAG also has the reaction of quick surface;Amorphous two-dimensional structure makes intensity and fracture toughness low;Modulus of elasticity (30-35MPa) is low, is approached with cortex bone;Machinable bio-vitric has good processing characteristics.
Current various scar moist dressings of dispelling can not be to the healing environment that wound provides, and surface of a wound scar effect of dispelling is poor.
The content of the invention
In view of the defects and deficiencies of the prior art, the present invention intends to provide a kind of scar of dispelling containing bioactivity glass Moist dressing and preparation method, it can effectively reduce dressing caused by scar, as the caesarean operation scar surface of a wound promotion heal, By bioactivity glass and the anti-inflammatory of chitosan, promote healing function, reduce inflammation and produce, long-acting bacteriostatic, promote the surface of a wound to be cured Close, particularly effective prevention of scar produces.
To achieve the above object, the present invention is using following technical scheme:It is using vaseline, atoleine as paste base Material, soaked by gauze or non-woven fabric plate under 75-105 degrees Celsius and dry shaping, bioactivity glass and chitosan It is prepared for main functional component, it is made up of the composition of raw materials of following parts by weight:Vaseline:65~80 parts, liquid stone Wax:5-18 parts, bioactivity glass:5~20 parts, medical glycerine:0.5-4.5 parts, chitosan:0.3~1.0 part, meche fits Amount.
The present invention is utilization " vaseline gauze pieces of cloth " technological incorporation nucleus:Such as bioactivity glass and chitosan, hair Bright one kind can effectively reduce dressing caused by scar, such as the promotion healing of the caesarean operation scar surface of a wound, pass through bioactivity glass The anti-inflammatory of glass and chitosan, promote healing function, reduce inflammation and produce, long-acting bacteriostatic, wound healing, be particularly effectively pre- Anti- scar produces.It is a functional medical device product having a extensive future.
Its main feature:
1st, the moistening seal of petrolatum gauze in itself, good healing environment is provided for wound healing;
2nd, neutralize and ooze out, anti-inflammatory:The specific PH of bio-vitric, sepage and anti-inflammatory are effectively neutralized, preferable healing environment is created, subtracts Few scabies secondary infection;
3rd, epithelium regeneration is induced:Bioactivity glass promotes synthesis and part of the 4th type collagen fiber albumen and epidermal growth factor Secrete, actively induce the propagation of epithelial cell, break up and divide a word with a hyphen at the end of a line, so as to effectively facilitate wound healing;
4th, surface of a wound scar is reduced:Adjust tissue cell proliferation, significantly shorten the wound repair time, so as to reduce the generation of scar.
The invention provides it is a kind of effectively prevent scar from producing, the moist dressing of wound healing, it can speed up wound Face healing, reduce scar, prevent from infecting.It can effectively reduce dressing caused by scar, such as the rush of the caesarean operation scar surface of a wound Enter healing, by bioactivity glass and the anti-inflammatory of chitosan, promote healing function, reduce inflammation and produce, long-acting bacteriostatic, promote Wound healing, particularly effective prevention of scar produce.
Embodiment
Embodiment 1
Present embodiment use technical scheme be:It is using vaseline, atoleine as paste host material, passes through yarn Cloth or non-woven fabric plate soak under 75 degrees Celsius dries shaping, and bioactivity glass and chitosan are prepared for main functional component Form, it is made up of the composition of raw materials of following parts by weight:Vaseline:65 parts, atoleine:5 parts, bioactivity glass:5 Part, medical glycerine:0.5 part, chitosan:0.3 part, appropriate meche.
The present invention is utilization " vaseline gauze pieces of cloth " technological incorporation nucleus:Such as bioactivity glass and chitosan, hair Bright one kind can effectively reduce dressing caused by scar, such as the promotion healing of the caesarean operation scar surface of a wound, pass through bioactivity glass The anti-inflammatory of glass and chitosan, promote healing function, reduce inflammation and produce, long-acting bacteriostatic, wound healing, be particularly effectively pre- Anti- scar produces.It is a functional medical device product having a extensive future.
Its main feature:
1st, the moistening seal of petrolatum gauze in itself, good healing environment is provided for wound healing;
2nd, neutralize and ooze out, anti-inflammatory:The specific PH of bio-vitric, sepage and anti-inflammatory are effectively neutralized, preferable healing environment is created, subtracts Few scabies secondary infection;
3rd, epithelium regeneration is induced:Bioactivity glass promotes synthesis and part of the 4th type collagen fiber albumen and epidermal growth factor Secrete, actively induce the propagation of epithelial cell, break up and divide a word with a hyphen at the end of a line, so as to effectively facilitate wound healing;
4th, surface of a wound scar is reduced:Adjust tissue cell proliferation, significantly shorten the wound repair time, so as to reduce the generation of scar.
The invention provides it is a kind of effectively prevent scar from producing, the moist dressing of wound healing, it can speed up wound Face healing, reduce scar, prevent from infecting.It can effectively reduce dressing caused by scar, such as the rush of the caesarean operation scar surface of a wound Enter healing, by bioactivity glass and the anti-inflammatory of chitosan, promote healing function, reduce inflammation and produce, long-acting bacteriostatic, promote Wound healing, particularly effective prevention of scar produce.
Embodiment 1
Present embodiment use technical scheme be:It is using vaseline, atoleine as paste host material, passes through yarn Cloth or non-woven fabric plate soak under 90 degrees Celsius dries shaping, and bioactivity glass and chitosan are prepared for main functional component Form, it is made up of the composition of raw materials of following parts by weight:Vaseline:70 parts, atoleine:10 parts, bioactivity glass:12 Part, medical glycerine:2 parts, chitosan:0.7 part, appropriate meche.
Embodiment 1
Present embodiment use technical scheme be:It is using vaseline, atoleine as paste host material, passes through yarn Cloth or non-woven fabric plate soak under 105 degrees Celsius dries shaping, and bioactivity glass and chitosan are main functional component system Standby to form, it is made up of the composition of raw materials of following parts by weight:Vaseline:80 parts, atoleine:18 parts, bioactivity glass: 20 parts, 4.5 parts of medical glycerine, chitosan:1.0 parts, appropriate meche.
It is described above, it is merely illustrative of the technical solution of the present invention and unrestricted, those of ordinary skill in the art are to this hair The other modifications or equivalent substitution that bright technical scheme is made, without departing from the spirit and scope of technical solution of the present invention, It all should cover among scope of the presently claimed invention.

Claims (4)

1. a kind of dispel scar moist dressing and preparation method containing bioactivity glass, it is characterised in that:It is with vaseline, liquid Paraffin is paste host material, is soaked by gauze or non-woven fabric plate under 75-105 degrees Celsius and dries shaping, bioactivity Glass and chitosan are prepared for main functional component, and it is made up of the composition of raw materials of following parts by weight:Vaseline:65~ 80 parts, atoleine:5-18 parts, bioactivity glass:5~20 parts, medical glycerine:0.5-4.5 parts, chitosan:0.3~1.0 Part, appropriate meche.
2. a kind of dispel scar moist dressing and preparation method containing bioactivity glass according to claim 1, its feature exist In:It is using vaseline, atoleine as paste host material, is soaked and dried in the air under 75 degrees Celsius by gauze or non-woven fabric plate Dry forming, bioactivity glass and chitosan are prepared for main functional component, its by following parts by weight composition of raw materials Composition:Vaseline:65 parts, atoleine:5 parts, bioactivity glass:5 parts, medical glycerine:0.5 part, chitosan:0.3 part, yarn Appropriate cloth.
3. a kind of dispel scar moist dressing and preparation method containing bioactivity glass according to claim 1, its feature exist In:It is using vaseline, atoleine as paste host material, is soaked and dried in the air under 90 degrees Celsius by gauze or non-woven fabric plate Dry forming, bioactivity glass and chitosan are prepared for main functional component, its by following parts by weight composition of raw materials Composition:Vaseline:70 parts, atoleine:10 parts, bioactivity glass:12 parts, medical glycerine:2 parts, chitosan:0.7 part, yarn Appropriate cloth.
4. a kind of dispel scar moist dressing and preparation method containing bioactivity glass according to claim 1, its feature exist In:It is using vaseline, atoleine as paste host material, is soaked by gauze or non-woven fabric plate under 105 degrees Celsius Shaping is dried, bioactivity glass and chitosan are prepared for main functional component, and it is matched somebody with somebody by the raw material of following parts by weight Fang Zucheng:Vaseline:80 parts, atoleine:18 parts, bioactivity glass:20 parts, 4.5 parts of medical glycerine, chitosan:1.0 Part, appropriate meche.
CN201710968187.8A 2017-10-18 2017-10-18 A kind of dispel scar moist dressing and preparation method containing bioactivity glass Pending CN107693833A (en)

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Application Number Priority Date Filing Date Title
CN201710968187.8A CN107693833A (en) 2017-10-18 2017-10-18 A kind of dispel scar moist dressing and preparation method containing bioactivity glass

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110038154A (en) * 2018-01-15 2019-07-23 张家港蓝智生物科技有限公司 Promote the dressing of wound healing and its preparation method applied to functional sponge
CN110038156A (en) * 2019-04-19 2019-07-23 南通蓝智新材料科技有限公司 Hemostasis promotees wound healing lotion and preparation method thereof
CN112370243A (en) * 2020-11-19 2021-02-19 南京平港生物技术有限公司 Sterile medical wet repair dressing and preparation method thereof
CN112451728A (en) * 2020-12-10 2021-03-09 精彩人生(湖北)再生医学科技有限公司 Bioactive glass dressing for human skin tissue recovery and preparation method thereof
CN115887748A (en) * 2022-12-13 2023-04-04 海南鸿翼医疗器械有限公司 Medical functional dressing for inhibiting bacteria and promoting healing and preparation method thereof

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1208338A (en) * 1996-09-19 1999-02-17 美国生物材料公司 Composition and method for acceleration of wound and burn healing
CN201131954Y (en) * 2006-12-22 2008-10-15 范传玲 Medical combination type sterile dressings
CN101991875A (en) * 2010-10-29 2011-03-30 上海硅健生物材料有限公司 Mesoporous bioactive glass and chitosan composite porous hemostatic material and preparation method thereof
CN104623718A (en) * 2015-01-22 2015-05-20 谈伟强 Chitosan petrolatum gauze and preparation method thereof
CN106039380A (en) * 2016-06-28 2016-10-26 邯郸沃伦多科技开发有限公司 Tissue wound repairing material and related product preparation method thereof

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1208338A (en) * 1996-09-19 1999-02-17 美国生物材料公司 Composition and method for acceleration of wound and burn healing
CN201131954Y (en) * 2006-12-22 2008-10-15 范传玲 Medical combination type sterile dressings
CN101991875A (en) * 2010-10-29 2011-03-30 上海硅健生物材料有限公司 Mesoporous bioactive glass and chitosan composite porous hemostatic material and preparation method thereof
CN104623718A (en) * 2015-01-22 2015-05-20 谈伟强 Chitosan petrolatum gauze and preparation method thereof
CN106039380A (en) * 2016-06-28 2016-10-26 邯郸沃伦多科技开发有限公司 Tissue wound repairing material and related product preparation method thereof

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110038154A (en) * 2018-01-15 2019-07-23 张家港蓝智生物科技有限公司 Promote the dressing of wound healing and its preparation method applied to functional sponge
CN110038156A (en) * 2019-04-19 2019-07-23 南通蓝智新材料科技有限公司 Hemostasis promotees wound healing lotion and preparation method thereof
CN110038156B (en) * 2019-04-19 2020-09-08 张家港蓝智生物科技有限公司 Hemostatic and wound healing promoting emulsion and preparation method thereof
CN112370243A (en) * 2020-11-19 2021-02-19 南京平港生物技术有限公司 Sterile medical wet repair dressing and preparation method thereof
CN112451728A (en) * 2020-12-10 2021-03-09 精彩人生(湖北)再生医学科技有限公司 Bioactive glass dressing for human skin tissue recovery and preparation method thereof
CN115887748A (en) * 2022-12-13 2023-04-04 海南鸿翼医疗器械有限公司 Medical functional dressing for inhibiting bacteria and promoting healing and preparation method thereof
CN115887748B (en) * 2022-12-13 2023-09-01 海南鸿翼医疗器械有限公司 Medical functional dressing for inhibiting bacteria and promoting healing and preparation method thereof

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Application publication date: 20180216