CN107510704A - A kind of antiallergy burn and scald paste containing bio-vitric - Google Patents
A kind of antiallergy burn and scald paste containing bio-vitric Download PDFInfo
- Publication number
- CN107510704A CN107510704A CN201710968100.7A CN201710968100A CN107510704A CN 107510704 A CN107510704 A CN 107510704A CN 201710968100 A CN201710968100 A CN 201710968100A CN 107510704 A CN107510704 A CN 107510704A
- Authority
- CN
- China
- Prior art keywords
- parts
- vitric
- terpinene
- alcohol
- burn
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
- A61K31/722—Chitin, chitosan
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/06—Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
- A61K33/08—Oxides; Hydroxides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/42—Phosphorus; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0014—Skin, i.e. galenical aspects of topical compositions
Abstract
A kind of antiallergy burn and scald paste containing bio-vitric, it is related to a kind of bio-vitric functional medical device product, and in particular to a kind of antiallergy burn and scald paste containing bio-vitric.It is using following technical scheme：It is using vaseline, atoleine as paste host material, and bioactivity glass and the alcohol of terpinene 4 are prepared for main functional component；It is formulated is formed by the raw material configuration of following parts by weight:Vaseline：45~70 parts, atoleine：3 25 parts, bioactivity glass：3~20 parts, the alcohol of terpinene 4：0.1 2.0 parts, medical glycerine：0.5 5.5 parts, chitosan：0.8~1.0 part, Sodium Hyaluronate：0.2~0.5 part.The present invention be it is a kind of effectively prevent fungal infection, anti-inflammatory it is anti-oxidant, can also wound healing burn and scald paste, it can speed up wound healing, reduces recurrence, prevents from infecting.
Description
Technical field
The present invention relates to a kind of bio-vitric functional medical device product, and in particular to a kind of anti-mistake containing bio-vitric
Quick burn and scald paste.
Background technology
Bio-vitric (bioglass) can realize specific biology, the glass of physiological function.Bio-vitric is implanted into human body
Cranial defect position, it can with bone tissue directly in conjunction with, play a part of repair bone tissue, recover its function.Bio-vitric is Buddhist
Flo-Rida-Low university American L.L. henries are very in invention in 1969.Its main component accounts for 45%Na2O, accounts for 25%CaO and 25%
SiO2 and account for 5%P2O5.If adding a small amount of other compositions, such as K2O, MgO, CaF2, B2O3, then can obtain a series of has reality
With the bio-vitric of value.
Bio-vitric has turned into the cross discipline of material science, biochemistry and molecular biology, due to bio-vitric
There is bioactivity, in tissue engineering bracket material, orthopaedics, dentistry, middle ear, treatment of cancer and pharmaceutical carrier etc.
Application prospect it is considerable.Mainly it is made up of Si, Na, Ca and P oxide.
Chinese patent ZL201310520955.5 discloses a kind of functional dressing and its production and use, and it is main
The bioactivity wound repair material that water is combined is added by alginate, chitosan, bioactivity glass,；It can be made into more
Formulation, mainly include gel and stick agent.But relative to antimycotic, hypo-allergenic effect is poor, oozed out for neutralization, anti-inflammatory,
Induction epithelium regeneration, reduce that surface of a wound scar is also difficult to reach should be effective.
Current antiallergy burn and scald paste, healing rate is slow, it is poor to the control effect of bleeding, easily cause infection hair
It is scorching.
The content of the invention
In view of the defects and deficiencies of the prior art, the present invention intends to provide a kind of antiallergy burning containing bio-vitric
Paste is scalded, it is applied to the promotion healing of the surface of a wound such as burn and scald and prevents allergy paste, passes through bioactivity glass and shell
The hemostasis of glycan, promote healing function, reduce bleeding, long-acting bacteriostatic, wound healing.It is a work(having a extensive future
Can property medical device product.
To achieve the above object, the present invention is using following technical scheme：It is using vaseline, atoleine as paste base
Material, bioactivity glass and terpinene-4-alcohol are prepared for main functional component；It is formulated by following parts by weight
Raw material configuration forms:Vaseline：45~70 parts, atoleine：3-25 parts, bioactivity glass：3~20 parts, terpinene -4-
Alcohol：0.1-2.0 parts, medical glycerine：0.5-5.5 parts, chitosan：0.8~1.0 part, Sodium Hyaluronate：0.2~0.5 part.
The present invention is utilization " bio-vitric " and " terpinene-4-alcohol ", " vaseline " technological incorporation nucleus：Such as micropore
Bioactivity glass and chitosan, terpinene-4-alcohol, a kind of promotion suitable for surface of a wound such as burn and scalds of invention are healed and prevented
Allergy paste, by the hemostasis of bioactivity glass and chitosan, promote healing function, reduce bleeding, long-acting bacteriostatic, promote wound
Heal in face.It is a functional medical device product having a extensive future.
Its main feature：
1st, it is antimycotic, it is hypo-allergenic：By extracting terpinene-4-alcohol from tea tree ethereal oil, be added in paste, have it is antimycotic,
Anti-inflammatory, anti-oxidant isoreactivity, effectively prevent new skin that burned patient is grown from continuing the allergy such as infection foaming, the necrosis that comes off and showing
As；
2nd, neutralize and ooze out, anti-inflammatory：The specific PH of bio-vitric, sepage and anti-inflammatory are effectively neutralized, preferable healing environment is created, subtracts
Few scabies secondary infection；
3rd, epithelium regeneration is induced：Bioactivity glass promotes synthesis and part of the 4th type collagen fiber albumen and epidermal growth factor
Secrete, actively induce the propagation of epithelial cell, break up and divide a word with a hyphen at the end of a line, so as to effectively facilitate wound healing；
4th, surface of a wound scar is reduced：Adjust tissue cell proliferation, significantly shorten the wound repair time, so as to reduce the generation of scar；
5th, contain appropriate vaseline in being formulated, the surface of a wound can be kept to be in the relative closed environment of moistening, wound healing.
The present invention be it is a kind of effectively prevent fungal infection, anti-inflammatory it is anti-oxidant, can also wound healing burn and scald paste
Agent, it can speed up wound healing, reduces recurrence, prevents from infecting.
Embodiment
Embodiment 1
Present embodiment use technical scheme be：It is using vaseline, atoleine as paste host material, and biology is living
Property glass and terpinene-4-alcohol are prepared for main functional component；It is formulated is formed by the raw material configuration of following parts by weight:
Vaseline：45 parts, atoleine：3 parts, bioactivity glass：3 parts, terpinene-4-alcohol：0.1 part, medical glycerine：0.5 part, shell
Glycan：0.8 part, Sodium Hyaluronate：0.2 part.
The present invention is utilization " bio-vitric " and " terpinene-4-alcohol ", " vaseline " technological incorporation nucleus：Such as micropore
Bioactivity glass and chitosan, terpinene-4-alcohol, a kind of promotion suitable for surface of a wound such as burn and scalds of invention are healed and prevented
Allergy paste, by the hemostasis of bioactivity glass and chitosan, promote healing function, reduce bleeding, long-acting bacteriostatic, promote wound
Heal in face.It is a functional medical device product having a extensive future.
Its main feature：1st, it is antimycotic, it is hypo-allergenic：By extracting terpinene-4-alcohol from tea tree ethereal oil, it is added to paste
In agent, there is antimycotic, anti-inflammatory, anti-oxidant isoreactivity, effectively prevent the new skin that burned patient is grown from continuing infection foaming, take off
Fall the allergic phenomenas such as necrosis；2nd, neutralize and ooze out, anti-inflammatory：The specific PH of bio-vitric, sepage and anti-inflammatory are effectively neutralized, created preferable
Healing environment, reduce scabies secondary infection；3rd, epithelium regeneration is induced：Bioactivity glass promotes the 4th type collagen fiber albumen and upper
The synthesis of skin growth factor is secreted with part, is actively induced the propagation of epithelial cell, is broken up and divide a word with a hyphen at the end of a line, is cured so as to effectively facilitate the surface of a wound
Close；4th, surface of a wound scar is reduced：Adjust tissue cell proliferation, significantly shorten the wound repair time, so as to reduce the generation of scar；5、
Contain appropriate vaseline in formula, the surface of a wound can be kept to be in the relative closed environment of moistening, wound healing.
The present invention be it is a kind of effectively prevent fungal infection, anti-inflammatory it is anti-oxidant, can also wound healing burn and scald paste
Agent, it can speed up wound healing, reduces recurrence, prevents from infecting.
Embodiment 2
Present embodiment use technical scheme be：It is using vaseline, atoleine as paste host material, and biology is living
Property glass and terpinene-4-alcohol are prepared for main functional component；It is formulated is formed by the raw material configuration of following parts by weight:
Vaseline：55 parts, atoleine：15 parts, bioactivity glass：12 parts, terpinene-4-alcohol：1 part, medical glycerine：2.5 parts, shell
Glycan：0.9 part, Sodium Hyaluronate：0.35 part.
Embodiment 3
Present embodiment use technical scheme be：It is using vaseline, atoleine as paste host material, and biology is living
Property glass and terpinene-4-alcohol are prepared for main functional component；It is formulated is formed by the raw material configuration of following parts by weight:
Vaseline：70 parts, atoleine：5 parts, bioactivity glass：20 parts, terpinene-4-alcohol：2.0 parts, medical glycerine：5.5 parts,
Chitosan：1.0th, Sodium Hyaluronate：0.5 part.
It is described above, it is merely illustrative of the technical solution of the present invention and unrestricted, those of ordinary skill in the art are to this hair
The other modifications or equivalent substitution that bright technical scheme is made, without departing from the spirit and scope of technical solution of the present invention,
It all should cover among scope of the presently claimed invention.
Claims (4)
- A kind of 1. antiallergy burn and scald paste containing bio-vitric, it is characterised in that：It is using vaseline, atoleine as paste Host material, bioactivity glass and terpinene-4-alcohol are prepared for main functional component；It is formulated by following parts by weight Raw material configuration form:Vaseline：45~70 parts, atoleine：3-25 parts, bioactivity glass：3~20 parts, terpinene -4- Alcohol：0.1-2.0 parts, medical glycerine：0.5-5.5 parts, chitosan：0.8~1.0 part, Sodium Hyaluronate：0.2~0.5 part.
- A kind of 2. antiallergy burn and scald paste containing bio-vitric according to claim 1, it is characterised in that：It is with all Intellectual circle, atoleine are paste host material, and bioactivity glass and terpinene-4-alcohol are prepared for main functional component； It is formulated is formed by the raw material configuration of following parts by weight:Vaseline：45 parts, atoleine：3 parts, bioactivity glass：3 parts, Terpinene-4-alcohol：0.1 part, medical glycerine：0.5 part, chitosan：0.8 part, Sodium Hyaluronate：0.2 part.
- A kind of 3. antiallergy burn and scald paste containing bio-vitric according to claim 1, it is characterised in that：It is with all Intellectual circle, atoleine are paste host material, and bioactivity glass and terpinene-4-alcohol are prepared for main functional component； It is formulated is formed by the raw material configuration of following parts by weight:Vaseline：55 parts, atoleine：15 parts, bioactivity glass：12 Part, terpinene-4-alcohol：1 part, medical glycerine：2.5 parts, chitosan：0.9 part, Sodium Hyaluronate：0.35 part.
- A kind of 4. antiallergy burn and scald paste containing bio-vitric according to claim 1, it is characterised in that：It is with all Intellectual circle, atoleine are paste host material, and bioactivity glass and terpinene-4-alcohol are prepared for main functional component； It is formulated is formed by the raw material configuration of following parts by weight:Vaseline：70 parts, atoleine：5 parts, bioactivity glass：20 Part, terpinene-4-alcohol：2.0 parts, medical glycerine：5.5 parts, chitosan：1.0th, Sodium Hyaluronate：0.5 part.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710968100.7A CN107510704A (en) | 2017-10-18 | 2017-10-18 | A kind of antiallergy burn and scald paste containing bio-vitric |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710968100.7A CN107510704A (en) | 2017-10-18 | 2017-10-18 | A kind of antiallergy burn and scald paste containing bio-vitric |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107510704A true CN107510704A (en) | 2017-12-26 |
Family
ID=60727297
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710968100.7A Pending CN107510704A (en) | 2017-10-18 | 2017-10-18 | A kind of antiallergy burn and scald paste containing bio-vitric |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107510704A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110680832A (en) * | 2018-07-04 | 2020-01-14 | 北京幸福益生再生医学科技有限公司 | Wound tissue self-derived regeneration and repair ointment and preparation method thereof |
| CN116354599A (en) * | 2023-04-06 | 2023-06-30 | 深圳先进技术研究院 | Boron-containing bioactive glass and preparation method and application thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6541042B1 (en) * | 1999-10-27 | 2003-04-01 | Bogar Ag | Therapeutically effective combination |
| CN105963771A (en) * | 2016-06-29 | 2016-09-28 | 广东泰宝医疗科技股份有限公司 | Medical dressing with bioactive components and method for preparing medical dressing |
| CN106039380A (en) * | 2016-06-28 | 2016-10-26 | 邯郸沃伦多科技开发有限公司 | Tissue wound repairing material and related product preparation method thereof |
-
2017
- 2017-10-18 CN CN201710968100.7A patent/CN107510704A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6541042B1 (en) * | 1999-10-27 | 2003-04-01 | Bogar Ag | Therapeutically effective combination |
| CN106039380A (en) * | 2016-06-28 | 2016-10-26 | 邯郸沃伦多科技开发有限公司 | Tissue wound repairing material and related product preparation method thereof |
| CN105963771A (en) * | 2016-06-29 | 2016-09-28 | 广东泰宝医疗科技股份有限公司 | Medical dressing with bioactive components and method for preparing medical dressing |
Non-Patent Citations (2)
| Title |
|---|
| RAIMUNDA SÂMIA NOGUEIRA BRILHANTE,ET AL: "Terpinen-4-ol, tyrosol, and β-lapachone as potential antifungals against dimorphic fungi", 《BRAZILIAN JOURNAL OF MICROBIOLOGY》 * |
| 叶倩等: "奶牛乳房炎防治的研究进展", 《奶牛乳房炎防治的研究进展》 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110680832A (en) * | 2018-07-04 | 2020-01-14 | 北京幸福益生再生医学科技有限公司 | Wound tissue self-derived regeneration and repair ointment and preparation method thereof |
| CN110680832B (en) * | 2018-07-04 | 2021-05-14 | 北京幸福益生高新技术有限公司 | Wound tissue self-derived regeneration and repair ointment and preparation method thereof |
| CN116354599A (en) * | 2023-04-06 | 2023-06-30 | 深圳先进技术研究院 | Boron-containing bioactive glass and preparation method and application thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Naseri et al. | Bioactive glasses in wound healing: hope or hype? | |
| AU2014386243A1 (en) | Sodium containing sol-gel derived bioactive glasses and uses thereof including hemostasis | |
| JP2019517533A (en) | External pharmaceutical composition for treatment of various wound wounds of skin and preparation method thereof | |
| CN103182070B (en) | External composition, and preparation and application thereof | |
| JP2011507845A5 (en) | ||
| CN106377791A (en) | Bamboo alginate functional dressing and preparation method thereof | |
| CN107510704A (en) | A kind of antiallergy burn and scald paste containing bio-vitric | |
| CN107693833A (en) | A kind of dispel scar moist dressing and preparation method containing bioactivity glass | |
| CN105288700A (en) | Medical thermo-sensitive hydrogel dressing and preparation method thereof | |
| CN103480032B (en) | A kind of argentiferous plural gel dressing and preparation method thereof | |
| CN107596435A (en) | A kind of gel of wound repair containing bioactivity glass | |
| CN106215227A (en) | A kind of effect type nose cavity hemostatic material of improvement and preparation method thereof | |
| Miguez-Pacheco et al. | Bioactive glasses for soft tissue engineering applications | |
| CN109700601B (en) | Hydrocolloid silicon dressing patch | |
| CN105616296B (en) | A kind of poplar Chinese holly flower itching-relieve skin-care mud | |
| WO2016080158A1 (en) | Biological film preparation for promoting wound healing and coating and protecting biological organs | |
| CN104548186A (en) | Composite material for prompting wound healing of soft tissue | |
| CN104225577A (en) | Double-treatment-course composite cell growth factor hydrogels as well as preparation methods and applications | |
| CN103191163B (en) | Skin wound repairing pharmaceutical composition | |
| CN108992699A (en) | A kind of functional Wound dressing and preparation method thereof containing active composite material | |
| CN113648450A (en) | Medical sterilization dressing and preparation method thereof | |
| CN113181420B (en) | Liquid wound dressing for quickly repairing skin superficial injury and preparation method thereof | |
| CN104257682B (en) | A kind of wound surface maintenance compositions and preparation | |
| CN109010906A (en) | A kind of biological glue and its working method for promoting postoperative wound local hemostasis and promoting postoperative wound epithelialization | |
| CN109248335A (en) | It is a kind of to promote the antibacterial tissue surface of a wound, promoting healing gel formula and production technology using terpinene-4-alcohol induced activity minerals |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20171226 |