CN107596435A - A kind of gel of wound repair containing bioactivity glass - Google Patents
A kind of gel of wound repair containing bioactivity glass Download PDFInfo
- Publication number
- CN107596435A CN107596435A CN201710784993.XA CN201710784993A CN107596435A CN 107596435 A CN107596435 A CN 107596435A CN 201710784993 A CN201710784993 A CN 201710784993A CN 107596435 A CN107596435 A CN 107596435A
- Authority
- CN
- China
- Prior art keywords
- gel
- base fluid
- bioactivity glass
- accounts
- wound repair
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Present invention is disclosed a kind of gel of wound repair containing bioactivity glass, it is made up of base fluid, bioactivity glass powder, Silica hydrogel, hyaluronic acid sodium gel, Peppermint essential oil, wherein, base fluid is mixed into by yellow petroleum jelly, atoleine, lanolin, wherein according to mass component ratio, yellow petroleum jelly accounts for the 60 80% of the base fluid, atoleine accounts for the 10 30% of the base fluid, lanolin accounts for the 10% of the base fluid, base fluid accounts for the 75 82% of wound repair gel, and bioactivity glass powder accounts for the 16 23% of wound repair gel：Silica hydrogel accounts for the 0.4 0.6% of wound repair gel, and hyaluronic acid sodium gel accounts for the 0.8 1.3% of wound repair gel：Peppermint essential oil accounts for the 0.3 0.6% of wound repair gel.Beneficial effect of the present invention is：With good wound repairing ability, moreover it is possible to anti-inflammation, the speed of wound healing.
Description
【Technical field】
The invention belongs to medical material tech field, more particularly to a kind of gel of wound repair containing bioactivity glass.
【Background technology】
Bioactivity glass (bioactiveglass, BAG) be one kind body tissue can be repaired, substitute with again
Life, there is the material that can make that bonding action is formed between tissue and material.BAG had found in 1969 by Hench, by SiO2,
The silicate glass of the bases such as Na2O, CaO and P2O5 composition.The catabolite of bioactivity glass can promote growth because
The generation of son, the procreation for promoting cell, the gene expression for strengthening Gegenbaur's cell and the growth of bone tissue.Be so far it is unique both
It can be combined with bone tissue bonding, while the bioartificial materials that and can is connected with soft tissue.
Chinese Patent Application No. CN201610170827.6 patents disclosed in 29 days disclose one kind within 06 month 2016
Wound repair gel, wound repair gel is counted in parts by weight to be made up of following component：10~40 parts of bioactive glass powder,
2~10 parts of polyethylene glycol 400,10~25 parts of Silica hydrogel, 5~15 parts of hyaluronic acid sodium gel, 0.1~2 part of acid particles, ice
0.5~5 part of piece, 0.1~0.5 part of absolute ethyl alcohol.Described bioactive glass powder consists of the following composition：SiO2：
45.0% (± 1%), CaO：24.5% (± 1%), Na2O：24.5% (± 1%), P2O5：6.0% (± 1%).The biology is living
Property glass wound repair gel is to chronic large area surface of a wound such as burn, bedsore, diabetes, contusion and all kinds of skin surface ulcer
Treatment there is the effect of notable, while the gel have prevent adhesion, antibacterial, moisturizing, the special efficacy such as growth for suppressing scar.
On above-mentioned technical proposal is generally based on, the research of correlation is made, wound repair speed is improved so as to reach
Effect.
A kind of it is therefore proposed that gel of wound repair containing bioactivity glass that can improve wound repair speed.
【The content of the invention】
It is a primary object of the present invention to provide a kind of surface of a wound containing bioactivity glass that can improve wound repair speed
Repair gel.
The present invention is achieved through the following technical solutions above-mentioned purpose：A kind of gel of wound repair containing bioactivity glass, its
It is characterised by：It is made up of base fluid, bioactivity glass powder, Silica hydrogel, hyaluronic acid sodium gel, Peppermint essential oil, wherein, base fluid
It is mixed into by yellow petroleum jelly, atoleine, lanolin, wherein according to mass component ratio, yellow petroleum jelly accounts for the 60- of the base fluid
80%, atoleine accounts for the 10-30% of the base fluid, and lanolin accounts for the 10% of the base fluid, and base fluid accounts for the 75- of wound repair gel
82%, bioactivity glass powder accounts for the 16-23% of wound repair gel：Silica hydrogel accounts for the 0.4-0.6% of wound repair gel,
Hyaluronic acid sodium gel accounts for the 0.8-1.3% of wound repair gel：Peppermint essential oil accounts for the 0.3-0.6% of wound repair gel.
The base fluid is according to yellow petroleum jelly：Atoleine：Lanolin=7:2:1 prepares, wherein, base fluid：Bioactivity glass
Glass powder：Silica hydrogel：Hyaluronic acid sodium gel：Peppermint essential oil is 80：18：0.5：1：0.5.
The base fluid is according to yellow petroleum jelly：Atoleine：Lanolin=6:3:1 prepares, wherein, base fluid：Bioactivity glass
Glass powder：Silica hydrogel：Hyaluronic acid sodium gel：Peppermint essential oil is 75：23：0.4：1.3：0.3.
The base fluid is according to yellow petroleum jelly：Atoleine：Lanolin=8:1:1 prepares, wherein, base fluid：Bioactivity glass
Glass powder：Silica hydrogel：Hyaluronic acid sodium gel：Peppermint essential oil is 82：16：0.6：0.8：0.6.
The molecular weight of hyaluronic acid sodium gel is 10000.
Compared with prior art, a kind of beneficial effect of the gel of wound repair containing bioactivity glass of the present invention is：Tool
There is good wound repairing ability, moreover it is possible to anti-inflammation, the speed of wound healing.
【Embodiment】
The present invention is a kind of gel of wound repair containing bioactivity glass, is coagulated by base fluid, bioactivity glass powder, silicon
Glue, hyaluronic acid sodium gel, Peppermint essential oil composition, wherein, base fluid is mixed into by yellow petroleum jelly, atoleine, lanolin, wherein
According to mass component ratio, yellow petroleum jelly accounts for the 60-80% of the base fluid, and atoleine accounts for the 10-30% of the base fluid, and lanolin accounts for this
The 10% of base fluid, and repair in gel, base fluid accounts for 75-82%, and bioactivity glass powder accounts for 16-23%：Silica hydrogel accounts for 0.4-
0.6%, hyaluronic acid sodium gel accounts for 0.8-1.3%：Peppermint essential oil accounts for 0.3-0.6%.
Technical scheme is described further with reference to embodiment.
Embodiment 1
First, yellow petroleum jelly is heated, makes its thawing, example in mass ratio is mixed in atoleine, is added lanolin, is pressed
Base fluid is formed according to mass ratio, base fluid is according to yellow petroleum jelly：Atoleine：Lanolin=7:2:1 is prepared.It is and fully mixed
Close, the base fluid of Extraction and determination.
Secondly, the bioactivity glass powder into base fluid, according to mass component ratio, base fluid：Bioactivity glass powder=50:
9, under the conditions of 20~35 DEG C, stir to bioactivity glass powder and be completely dissolved；
Silica hydrogel is added into mixed liquor again, according to mass component ratio, base fluid：Silica hydrogel=160:1, in 20~35 DEG C of bars
Under part, it is sufficiently stirred to form glue,
The hyaluronic acid sodium gel of 10000 molecular weight is added, according to mass component ratio, base fluid：Hyaluronic acid sodium gel
=80:1, under the conditions of 20~35 DEG C, it is sufficiently stirred to form glue；
Then Peppermint essential oil is added according to mass component ratio, base fluid：Peppermint essential oil=160:1, mixing is stirred, is formed
Repair gel.
Therefore, according to mass component ratio, base fluid：Bioactivity glass powder：Silica hydrogel：Hyaluronic acid sodium gel：Peppermint
Essential oil is 80：18：0.5：1：0.5.
Silica hydrogel is at least one of methyl vinyl silicon oil, methyl-silicone oil, ethyl silicon oil.Described Sodium Hyaluronate
Gel is prepared by following methods：Hyal powder first is infiltrated with appropriate glycerine, after being uniformly dispersed, is added a small amount of
Water dissolves；Wherein the mass percent of Sodium Hyaluronate is 0.5%~1%, and the mass percent of glycerine and distilled water is
7-8:2-3。
Embodiment 2
First, yellow petroleum jelly is heated, makes its thawing, example in mass ratio is mixed in atoleine, is added lanolin, is pressed
Base fluid is formed according to mass ratio, base fluid is according to yellow petroleum jelly：Atoleine：Lanolin=6:3:1 is prepared.It is and fully mixed
Close, the base fluid of Extraction and determination.
In the way of embodiment 1, according to mass component ratio, base fluid：Bioactivity glass powder：Silica hydrogel：Hyalomitome
Sour sodium gel：Peppermint essential oil is 75：23：0.4：1.3：0.3.
Secondly, the bioactivity glass powder into base fluid, under the conditions of 20~35 DEG C, stir complete to bioactivity glass powder
Fully dissolved；
Silica hydrogel is added into mixed liquor again, under the conditions of 20~35 DEG C, is sufficiently stirred to form glue,
The hyaluronic acid sodium gel of 10000 molecular weight is added, under the conditions of 20~35 DEG C, is sufficiently stirred to form glue；
Then Peppermint essential oil is added, is stirred mixing, is formed and repairs gel.
Silica hydrogel is at least one of methyl vinyl silicon oil, methyl-silicone oil, ethyl silicon oil.Described Sodium Hyaluronate
Gel is prepared by following methods：Hyal powder first is infiltrated with appropriate glycerine, after being uniformly dispersed, is added a small amount of
Water dissolves；Wherein the mass percent of Sodium Hyaluronate is 0.5%~1%, and the mass percent of glycerine and distilled water is
7-8:2-3。
Embodiment 3：
First, yellow petroleum jelly is heated, makes its thawing, example in mass ratio is mixed in atoleine, is added lanolin, is pressed
Base fluid is formed according to mass ratio, base fluid is according to yellow petroleum jelly：Atoleine：Lanolin=8:1:1 is prepared.It is and fully mixed
Close, the base fluid of Extraction and determination.
In the way of embodiment 1, according to mass component ratio, base fluid：Bioactivity glass powder：Silica hydrogel：Hyalomitome
Sour sodium gel：Peppermint essential oil is 82：16：0.6：0.8：0.6.
Secondly, the bioactivity glass powder into base fluid, under the conditions of 20~35 DEG C, stir complete to bioactivity glass powder
Fully dissolved；
Silica hydrogel is added into mixed liquor again, under the conditions of 20~35 DEG C, is sufficiently stirred to form glue,
The hyaluronic acid sodium gel of 10000 molecular weight is added, under the conditions of 20~35 DEG C, is sufficiently stirred to form glue；
Then Peppermint essential oil is added, is stirred mixing, is formed and repairs gel.
Silica hydrogel is at least one of methyl vinyl silicon oil, methyl-silicone oil, ethyl silicon oil.Described Sodium Hyaluronate
Gel is prepared by following methods：Hyal powder first is infiltrated with appropriate glycerine, after being uniformly dispersed, is added a small amount of
Water dissolves；Wherein the mass percent of Sodium Hyaluronate is 0.5%~1%, and the mass percent of glycerine and distilled water is
7-8:2-3。
Embodiment 4
First, yellow petroleum jelly is heated, makes its thawing, example in mass ratio is mixed in atoleine, is added lanolin, is pressed
Base fluid is formed according to mass ratio, base fluid is according to yellow petroleum jelly：Atoleine：Lanolin=7:2:1 is prepared.It is and fully mixed
Close, the base fluid of Extraction and determination.
In the way of embodiment 1, according to mass component ratio, base fluid：Bioactivity glass powder：Silica hydrogel：Hyalomitome
Sour sodium gel：Peppermint essential oil is 75：23：0.4：1.3：0.3.
Secondly, the bioactivity glass powder into base fluid, under the conditions of 20~35 DEG C, stir complete to bioactivity glass powder
Fully dissolved；
Silica hydrogel is added into mixed liquor again, under the conditions of 20~35 DEG C, is sufficiently stirred to form glue,
The hyaluronic acid sodium gel of 10000 molecular weight is added, under the conditions of 20~35 DEG C, is sufficiently stirred to form glue；
Then Peppermint essential oil is added, is stirred mixing, is formed and repairs gel.
Embodiment 5
First, yellow petroleum jelly is heated, makes its thawing, example in mass ratio is mixed in atoleine, is added lanolin, is pressed
Base fluid is formed according to mass ratio, base fluid is according to yellow petroleum jelly：Atoleine：Lanolin=7:2:1 is prepared.It is and fully mixed
Close, the base fluid of Extraction and determination.
In the way of embodiment 1, according to mass component ratio, base fluid：Bioactivity glass powder：Silica hydrogel：Hyalomitome
Sour sodium gel：Peppermint essential oil is 82：16：0.6：0.8：0.6.
Secondly, the bioactivity glass powder into base fluid, under the conditions of 20~35 DEG C, stir complete to bioactivity glass powder
Fully dissolved；
Silica hydrogel is added into mixed liquor again, under the conditions of 20~35 DEG C, is sufficiently stirred to form glue,
The hyaluronic acid sodium gel of 10000 molecular weight is added, under the conditions of 20~35 DEG C, is sufficiently stirred to form glue；
Then Peppermint essential oil is added, is stirred mixing, is formed and repairs gel.
Embodiment 6
First, yellow petroleum jelly is heated, makes its thawing, example in mass ratio is mixed in atoleine, is added lanolin, is pressed
Base fluid is formed according to mass ratio, base fluid is according to yellow petroleum jelly：Atoleine：Lanolin=6:3:1 is prepared.It is and fully mixed
Close, the base fluid of Extraction and determination.
In the way of embodiment 1, according to mass component ratio, base fluid：Bioactivity glass powder：Silica hydrogel：Hyalomitome
Sour sodium gel：Peppermint essential oil is 80：18：0.5：1：0.5.
Secondly, the bioactivity glass powder into base fluid, under the conditions of 20~35 DEG C, stir complete to bioactivity glass powder
Fully dissolved；
Silica hydrogel is added into mixed liquor again, under the conditions of 20~35 DEG C, is sufficiently stirred to form glue,
The hyaluronic acid sodium gel of 10000 molecular weight is added, under the conditions of 20~35 DEG C, is sufficiently stirred to form glue；
Then Peppermint essential oil is added, is stirred mixing, is formed and repairs gel.
Embodiment 7
First, yellow petroleum jelly is heated, makes its thawing, example in mass ratio is mixed in atoleine, is added lanolin, is pressed
Base fluid is formed according to mass ratio, base fluid is according to yellow petroleum jelly：Atoleine：Lanolin=6:3:1 is prepared.It is and fully mixed
Close, the base fluid of Extraction and determination.
In the way of embodiment 1, according to mass component ratio, base fluid：Bioactivity glass powder：Silica hydrogel：Hyalomitome
Sour sodium gel：Peppermint essential oil is 82：16：0.6：0.8：0.6.
Secondly, the bioactivity glass powder into base fluid, under the conditions of 20~35 DEG C, stir complete to bioactivity glass powder
Fully dissolved；
Silica hydrogel is added into mixed liquor again, under the conditions of 20~35 DEG C, is sufficiently stirred to form glue,
The hyaluronic acid sodium gel of 10000 molecular weight is added, under the conditions of 20~35 DEG C, is sufficiently stirred to form glue；
Then Peppermint essential oil is added, is stirred mixing, is formed and repairs gel.
Embodiment 8
First, yellow petroleum jelly is heated, makes its thawing, example in mass ratio is mixed in atoleine, is added lanolin, is pressed
Base fluid is formed according to mass ratio, base fluid is according to yellow petroleum jelly：Atoleine：Lanolin=8:1:1 is prepared.It is and fully mixed
Close, the base fluid of Extraction and determination.
In the way of embodiment 1, according to mass component ratio, base fluid：Bioactivity glass powder：Silica hydrogel：Hyalomitome
Sour sodium gel：Peppermint essential oil is 80：18：0.5：1：0.5..
Secondly, the bioactivity glass powder into base fluid, under the conditions of 20~35 DEG C, stir complete to bioactivity glass powder
Fully dissolved；
Silica hydrogel is added into mixed liquor again, under the conditions of 20~35 DEG C, is sufficiently stirred to form glue,
The hyaluronic acid sodium gel of 10000 molecular weight is added, under the conditions of 20~35 DEG C, is sufficiently stirred to form glue；
Then Peppermint essential oil is added, is stirred mixing, is formed and repairs gel.
Embodiment 9
First, yellow petroleum jelly is heated, makes its thawing, example in mass ratio is mixed in atoleine, is added lanolin, is pressed
Base fluid is formed according to mass ratio, base fluid is according to yellow petroleum jelly：Atoleine：Lanolin=8:1:1 is prepared.It is and fully mixed
Close, the base fluid of Extraction and determination.
In the way of embodiment 1, according to mass component ratio, base fluid：Bioactivity glass powder：Silica hydrogel：Hyalomitome
Sour sodium gel：Peppermint essential oil is 75：23：0.4：1.3：0.3.
Secondly, the bioactivity glass powder into base fluid, under the conditions of 20~35 DEG C, stir complete to bioactivity glass powder
Fully dissolved；
Silica hydrogel is added into mixed liquor again, under the conditions of 20~35 DEG C, is sufficiently stirred to form glue,
The hyaluronic acid sodium gel of 10000 molecular weight is added, under the conditions of 20~35 DEG C, is sufficiently stirred to form glue；
Then Peppermint essential oil is added, is stirred mixing, is formed and repairs gel.
The hyaluronic acid of each embodiment is 10000 low molecule amount in the present invention,
Bioactivity glass aperture is in 50 microns.
Verified by zoopery, the product not only has good wound repairing ability, moreover it is possible to anti-inflammation, improve wound
The speed of face healing.
According to existing experimental method, the concrete operations of zoopery are as follows：It is left in 200g from 60 SD rats, body weight
The right side, 8 week old, each 30 of male and female, divide 3 groups, separate cage.24h carries out back depilation processing, depilation to experimental animal before experiment
Routine feeding afterwards；Start to test, all experiment mouses are carried out with intraperitoneal injection 300mg/kg 10% chloraldurate solution
Anesthesia, normal sterile processing；In carrying out mark with a diameter of 1.5cm circular hole at 1cm by SD rat back backbones both sides, then
Epidermis, corium and subcutaneous connective tissue are removed with scalpel, per side 2,5 wounds of every mouse, 5 wounds are applied respectively
The gel of embodiment 1-3 synthesis provided by the invention compares the most with existing gel, is finally wrapped up respectively with sterile gauze, often
Day dosing once, observes the healing state of the surface of a wound.
In addition, being smeared respectively a variety of gels by human body, subject is provided to gel use feeling, by as above
The result：
| Project | Healing time (my god) | Subject assessment |
| Embodiment 1 | 5 | There is refrigerant sense, without any excitement |
| Embodiment 2 | 5.5 | There is refrigerant sense, without any excitement |
| Embodiment 3 | 5.5 | There is refrigerant sense, without any excitement |
| Embodiment 4 | 5 | There is refrigerant sense, without any excitement |
| Embodiment 5 | 5 | There is refrigerant sense, without any excitement |
| Embodiment 6 | 5.5 | There is refrigerant sense, without any excitement |
| Embodiment 7 | 5.5 | There is refrigerant sense, without any excitement |
| Embodiment 8 | 5.5 | There is refrigerant sense, without any excitement |
| Embodiment 9 | 5.5 | There is refrigerant sense, without any excitement |
| Control group 1 | 6 | Without refrigerant sense, without any excitement |
| Control group 2 | 6 | Without refrigerant sense, a little excitement |
Above-described is only some embodiments of the present invention.For the person of ordinary skill of the art, not
On the premise of departing from the invention design, various modifications and improvements can be made, these belong to the protection model of the present invention
Enclose.
Claims (5)
- A kind of 1. gel of wound repair containing bioactivity glass, it is characterised in that：Coagulated by base fluid, bioactivity glass powder, silicon Glue, hyaluronic acid sodium gel, Peppermint essential oil composition, wherein, base fluid is mixed into by yellow petroleum jelly, atoleine, lanolin, wherein According to mass component ratio, yellow petroleum jelly accounts for the 60-80% of the base fluid, and atoleine accounts for the 10-30% of the base fluid, and lanolin accounts for this The 10% of base fluid, base fluid account for the 75-82% of wound repair gel, and bioactivity glass powder accounts for the 16- of wound repair gel 23%：Silica hydrogel accounts for the 0.4-0.6% of wound repair gel, and hyaluronic acid sodium gel accounts for the 0.8-1.3% of wound repair gel： Peppermint essential oil accounts for the 0.3-0.6% of wound repair gel.
- 2. the gel of wound repair containing bioactivity glass as claimed in claim 1, it is characterised in that：The base fluid is according to yellow all Intellectual circle：Atoleine：Lanolin=7:2:1 prepares, wherein, base fluid：Bioactivity glass powder：Silica hydrogel：Sodium Hyaluronate Gel：Peppermint essential oil is 80：18：0.5：1：0.5.
- 3. the gel of wound repair containing bioactivity glass as claimed in claim 1, it is characterised in that：The base fluid is according to yellow all Intellectual circle：Atoleine：Lanolin=6:3:1 prepares, wherein, base fluid：Bioactivity glass powder：Silica hydrogel：Sodium Hyaluronate Gel：Peppermint essential oil is 75：23：0.4：1.3：0.3.
- 4. the gel of wound repair containing bioactivity glass as claimed in claim 1, it is characterised in that：The base fluid is according to yellow all Intellectual circle：Atoleine：Lanolin=8:1:1 prepares, wherein, base fluid：Bioactivity glass powder：Silica hydrogel：Sodium Hyaluronate Gel：Peppermint essential oil is 82：16：0.6：0.8：0.6.
- 5. the gel of wound repair containing bioactivity glass as claimed in claim 1, it is characterised in that：Hyaluronic acid sodium gel Molecular weight is 10000.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710784993.XA CN107596435A (en) | 2017-09-04 | 2017-09-04 | A kind of gel of wound repair containing bioactivity glass |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710784993.XA CN107596435A (en) | 2017-09-04 | 2017-09-04 | A kind of gel of wound repair containing bioactivity glass |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN107596435A true CN107596435A (en) | 2018-01-19 |
Family
ID=61057343
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710784993.XA Pending CN107596435A (en) | 2017-09-04 | 2017-09-04 | A kind of gel of wound repair containing bioactivity glass |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN107596435A (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110368517A (en) * | 2019-07-26 | 2019-10-25 | 深圳阳光环球玻璃有限公司 | A kind of wound hemostasis reparation bioactivity glass medical material |
| CN112057681A (en) * | 2020-10-23 | 2020-12-11 | 温州医科大学慈溪生物医药研究院 | Composition containing bioglass ceramics and application thereof in scar repair |
| CN114558168A (en) * | 2022-03-25 | 2022-05-31 | 白绍静 | Active induced wound repair gel and preparation method and manufacturing equipment thereof |
| CN116328017A (en) * | 2023-04-13 | 2023-06-27 | 江苏汇锦然医疗器械有限公司 | Highly antibacterial vertical absorption alginate dressing and preparation method thereof |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1252995A (en) * | 1998-11-06 | 2000-05-17 | 陈军 | Burn cream |
| WO2007072065A3 (en) * | 2005-12-23 | 2007-10-04 | Advanced Bio Technologies Inc | Silicone composition |
| CN104983754A (en) * | 2015-06-16 | 2015-10-21 | 吉林万通药业集团郑州万通复升药业股份有限公司 | Callus ointment and preparing method thereof |
| CN104984384A (en) * | 2015-07-27 | 2015-10-21 | 南阳市汇博生物技术有限公司 | Medical antibacterial dressing and preparation method thereof |
| CN105709271A (en) * | 2016-03-24 | 2016-06-29 | 广东泰宝医疗科技股份有限公司 | Glass wound repair gel with biological activity and preparation method thereof |
| CN105963771A (en) * | 2016-06-29 | 2016-09-28 | 广东泰宝医疗科技股份有限公司 | Medical dressing with bioactive components and method for preparing medical dressing |
-
2017
- 2017-09-04 CN CN201710784993.XA patent/CN107596435A/en active Pending
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1252995A (en) * | 1998-11-06 | 2000-05-17 | 陈军 | Burn cream |
| WO2007072065A3 (en) * | 2005-12-23 | 2007-10-04 | Advanced Bio Technologies Inc | Silicone composition |
| CN104983754A (en) * | 2015-06-16 | 2015-10-21 | 吉林万通药业集团郑州万通复升药业股份有限公司 | Callus ointment and preparing method thereof |
| CN104984384A (en) * | 2015-07-27 | 2015-10-21 | 南阳市汇博生物技术有限公司 | Medical antibacterial dressing and preparation method thereof |
| CN105709271A (en) * | 2016-03-24 | 2016-06-29 | 广东泰宝医疗科技股份有限公司 | Glass wound repair gel with biological activity and preparation method thereof |
| CN105963771A (en) * | 2016-06-29 | 2016-09-28 | 广东泰宝医疗科技股份有限公司 | Medical dressing with bioactive components and method for preparing medical dressing |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110368517A (en) * | 2019-07-26 | 2019-10-25 | 深圳阳光环球玻璃有限公司 | A kind of wound hemostasis reparation bioactivity glass medical material |
| CN112057681A (en) * | 2020-10-23 | 2020-12-11 | 温州医科大学慈溪生物医药研究院 | Composition containing bioglass ceramics and application thereof in scar repair |
| CN114558168A (en) * | 2022-03-25 | 2022-05-31 | 白绍静 | Active induced wound repair gel and preparation method and manufacturing equipment thereof |
| CN116328017A (en) * | 2023-04-13 | 2023-06-27 | 江苏汇锦然医疗器械有限公司 | Highly antibacterial vertical absorption alginate dressing and preparation method thereof |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN107596435A (en) | A kind of gel of wound repair containing bioactivity glass | |
| CN104587518A (en) | Hyaluronic acid dressing and preparation method thereof | |
| CN105194719B (en) | A kind of facial wound repairs dressing, application and preparation method thereof | |
| CN108210887A (en) | A kind of Medical cold application and preparation method thereof | |
| CN106606798A (en) | Medical hyaluronic acid bioremediation plaster and preparation method thereof | |
| CN114191597B (en) | Liquid dressing for repairing skin wound surface and preparation method and application thereof | |
| CN101780031B (en) | Induced gel used for repairing skin wound surfaces or cervical mucosa | |
| CN103751833B (en) | Medical antibacterial wound dressing and preparation method thereof | |
| CN105963771B (en) | A kind of medical dressing and preparation method thereof containing bioactive ingredients | |
| CN110169948A (en) | A kind of canker sore of the material containing bioactive minerals repairs gel and preparation method thereof | |
| CN107007874A (en) | A kind of silicon substrate wound repair aqueous gel and preparation method thereof | |
| CN103083712A (en) | Stem cells or other bioactive substances doped surgical dressing | |
| CN105013001A (en) | Medical biological hydrogel function dressing for gynecology and preparation method of dressing | |
| CN104382843B (en) | A kind of skin repair gel | |
| CN106794195A (en) | Method and composition for strengthening and extending the cosmetic outcome of No operation skin intervention | |
| CN109010124A (en) | A kind of ocean essence gynaecology bacteriostatic gel and preparation method thereof | |
| WO2007033591A1 (en) | Active prosthetic material for wounds | |
| CN101596310A (en) | A kind of artificial substrate membrane emulsifying paste that is used for wound repair | |
| CN114533654B (en) | Low-molecular chondroitin sulfate composite hydrogel and preparation method and application thereof | |
| CN107551090A (en) | One kind, which is nourished, repairs gel | |
| Zhu et al. | Effectiveness of nano bioactive glass fiber loaded with platelet-rich plasma on thermal wound healing process in rats | |
| CN104225577A (en) | Double-treatment-course composite cell growth factor hydrogels as well as preparation methods and applications | |
| CN108079013A (en) | A kind of preparation method and application for relieving pain bioactivity glass powder | |
| CN107510704A (en) | A kind of antiallergy burn and scald paste containing bio-vitric | |
| CN103191163B (en) | Skin wound repairing pharmaceutical composition |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20180119 |
|
| RJ01 | Rejection of invention patent application after publication |