CN104983754A - Callus ointment and preparing method thereof - Google Patents

Abstract

The invention discloses a callus ointment and a preparing method thereof. The callus ointment comprises, by mass, 2-5 parts of rivanol, 1-3 parts of cure all, 180-220 parts of refined gauze, 30-35 parts of zinc oxide, 28-32 parts of rosin, 22-28 parts of rubber, 5-7 parts of yellow soft paraffin, 2-5 parts of wool fat and 0.2-0.7 parts of liquid-state paraffin. The callus ointment is obvious in effect, stable in performance, simple in process, fewer in technological process and low in cost.

Description

Wound healing cream and preparation method thereof

Technical field

The present invention relates to drug world, particularly relate to wound healing cream and preparation method thereof.

Background technology

Wound healing refers to that body suffers External Force Acting, and the process more again after disconnected or defect appears in the tissue such as skin, is to comprise the complex combination that the regeneration of various tissue and granulation tissue hyperplasia, scar tissue formed, and shows the synergism of various process.

First degree wound is only limitted to skin epidermis, and slightly severe one has skin and subcutaneous tissue fracture, and occurs wound; Serious wound can have muscle, tendon, neural fracture and fracture.The following basic process having the wound healing of wound.

At present, for shallow table wound, protect from infection and promote the wound healing medicine of wound healing, its effect is not obvious, and unstable properties, complex process, flow process is many, and cost is higher.

Therefore, prior art has yet to be improved and developed.

Summary of the invention

In view of above-mentioned the deficiencies in the prior art, the object of the present invention is to provide wound healing cream and preparation method thereof, be intended to solve the problem that existing wound healing efficacy of drugs is not obvious, unstable properties, complex process, cost are high.

Technical scheme of the present invention is as follows:

Wound healing cream, is characterized in that, by mass parts, comprising:

Ethacridine 2 ~ 5 parts;

Cure-all 1 ~ 3 part;

Essence 180 ~ 220 parts, gauze;

Zinc oxide 30 ~ 35 parts;

Colophonium 28 ~ 32 parts;

Rubber 22 ~ 28 parts;

Yellow Vaselin 5 ~ 7 parts;

Lanoline 2 ~ 5 parts;

Paraffin hydrocarbons 0.2 ~ 0.7 part.

Described wound healing cream, is characterized in that, by mass parts, comprising:

Ethacridine 3 parts;

Cure-all 1.5 parts;

Essence 200 parts, gauze;

Zinc oxide 32.5 parts;

Colophonium 29.5 parts;

Rubber 25.5 parts;

Yellow Vaselin 6.5 parts;

Lanoline 3.5 parts;

Paraffin hydrocarbons 0.5 part.

A preparation method for wound healing cream as above, is characterized in that, comprise step:

First ethacridine and cure-all adding distil water are dissolved, after all dissolving, add smart gauze and soak 8 hours, make leaching medicine even, take out, dry, cut, folded bar obtains medicine gauze;

By rubber through refining glue, immersion, playing glue process, filter, leave standstill, be coated with cream, cut, make carrier;

Carrier and the combination of medicine gauze, sterilization, finally with the plastic sheeting lid lining of sterilization, cuts, to obtain final product.

Beneficial effect: wound healing cream provided by the present invention and preparation method thereof, it adopts ethacridine 2 ~ 5 parts; Cure-all 1 ~ 3 part; Essence 180 ~ 220 parts, gauze; Zinc oxide 30 ~ 35 parts; Colophonium 28 ~ 32 parts; Rubber 22 ~ 28 parts; Yellow Vaselin 5 ~ 7 parts; Lanoline 2 ~ 5 parts; The formula that paraffin hydrocarbons is 0.2 ~ 0.7 part, its effect is obvious, stable performance, and technique is simple, and flow process is few, and cost is low.

Detailed description of the invention

The invention provides wound healing cream and preparation method thereof, for making object of the present invention, technical scheme and effect clearly, clearly, the present invention is described in more detail below.Should be appreciated that specific embodiment described herein only in order to explain the present invention, be not intended to limit the present invention.

Wound healing cream, is characterized in that, by mass parts, comprising:

Ethacridine 2 ~ 5 parts;

Cure-all 1 ~ 3 part;

Essence 180 ~ 220 parts, gauze;

Zinc oxide 30 ~ 35 parts;

Colophonium 28 ~ 32 parts;

Rubber 22 ~ 28 parts;

Yellow Vaselin 5 ~ 7 parts;

Lanoline 2 ~ 5 parts;

Paraffin hydrocarbons 0.2 ~ 0.7 part.

Further, described wound healing cream, is characterized in that, by mass parts, comprising:

Ethacridine 3 parts;

Cure-all 1.5 parts;

Essence 200 parts, gauze;

Zinc oxide 32.5 parts;

Colophonium 29.5 parts;

Rubber 25.5 parts;

Yellow Vaselin 6.5 parts;

Lanoline 3.5 parts;

Paraffin hydrocarbons 0.5 part.

The present invention also provides a kind of preparation method of wound healing cream as above, and it comprises step:

First ethacridine and cure-all adding distil water are dissolved, after all dissolving, add smart gauze and soak 8 hours, make leaching medicine even, take out, dry, cut, folded bar obtains medicine gauze;

By rubber through refining glue, immersion, playing glue process, filter, leave standstill, be coated with cream, cut, make carrier;

Carrier and the combination of medicine gauze, sterilization, finally with the plastic sheeting lid lining of sterilization, cuts, to obtain final product.

Embodiment 1

Ethacridine 3kg;

Cure-all 1.5 kg;

Essence gauze 200 kg;

Zinc oxide 32.5 kg;

Colophonium 29.5 kg;

Rubber 25.5 kg;

Yellow Vaselin 6.5 kg;

Lanoline 3.5 kg;

Paraffin hydrocarbons 0.5 kg.

Embodiment 2

Ethacridine 2kg;

Cure-all 1 kg;

Essence gauze 220 kg;

Zinc oxide 30kg;

Colophonium 28kg;

Rubber 28 kg;

Yellow Vaselin 7 kg;

Lanoline 2 kg;

Paraffin hydrocarbons 0.7 kg.

Embodiment 3

Ethacridine 5kg;

Cure-all 3kg;

Essence gauze 180 kg;

Zinc oxide 35kg;

Colophonium 32 kg;

Rubber 22 kg;

Yellow Vaselin 5kg;

Lanoline 5kg;

Paraffin hydrocarbons 0.2 kg.

By the formula of embodiment 1, prepare as follows:

First 3kg ethacridine and 1.5 kg cure-alls are added 1000L distilled water to dissolve, after all dissolving, add 200 kg essence gauzes and soak 8 hours, make leaching medicine even, take out, dry, cut, folded bar obtains medicine gauze;

By 25.5 kg rubber through refining glue, immersion, playing glue process, break into cream slurry, filter, leave standstill, be coated with cream, cut, make carrier;

Its detailed process comprises:

1, by lanoline, Yellow Vaselin and liquid paraffin three kinds of materials, heating makes it molten altogether, is prepared into the oils and fats spice mixed;

2, steep glue: rubber is cut into strip (5-6cm long, as 5.5cm), put broken glue on rubber mixing machine, and immerse in above-mentioned oils and fats spice simultaneously, oils and fats spice is adhered on rubber surface and evenly must steep the rubber after glue, then static 15 ~ 72 hours, for subsequent use;

As adopted XK-300 type rubber mixing machine, then mix up roll spacing " 2 " gear of rubber mixing machine, by the strip rubber cut into, put on rubber mixing machine and break glue 3 times, after put into glue bucket, metering, then mix up roll spacing " 1 " gear, processed rubber one time, and immerse in the above-mentioned oils and fats spice mixed simultaneously and enclose fast, oils and fats spice is adhered to evenly on the surface at rubber mass, then puts non-uncovered static 15 ~ 72 hours (as 48 hours) in bubble glue container, for subsequent use.

3, mixing: the rubber after bubble glue puts kneading 50-60 minute in kneader, then zinc oxide and Colophonium is first joined in kneader, after mixing 50-60 minute, static 15 ~ 72 hours, for subsequent use;

Kneader can adopt NH-500 kneader, the rubber first got after bubble glue puts kneading 50-60 minute (as 55 minutes) in kneader, again zinc oxide and Colophonium are successively joined in kneader, after mixing 50-60 minute (as 55 minutes), start discharging, put in clean container static 15 ~ 72 hours (as 48 hours), for subsequent use.

4, slightly refine: get mixing after sizing material slightly refine;

Thick refining can adopt XK-300 type rubber mixing machine, then regulates rubber mixing machine roll spacing be after " 2 " gear, get mixing after sizing material, upper machine, slightly refines first pass, after then the roll spacing of rubber mixing machine being adjusted to " 1.5 " gear, the operation of repetition first pass.Regulate rubber mixing machine roll spacing to be after " 1 " gear, repeat the operation of a time.

5, refine: the sizing material got after thick refining carries out refine, then leaves standstill 15 ~ 72 hours, for subsequent use;

This step can adopt XK-300 type rubber mixing machine equally, regulates rubber mixing machine roll spacing to be after " 0.2 " gear, gets the sizing material after thick refining, upper machine, refine 1 time, is put by sizing material in clean container and leave standstill 15 ~ 72 hours (as 48 hours) after terminating, for subsequent use.

6, divide dish: be placed in by the sizing material after refine and rubber mixing machine carries out refining glue divide dish, point be filled on drip pan, for subsequent use;

This step regulates rubber mixing machine roll spacing be after " 1 " gear, is placed in by the sizing material after refine rubber mixing machine carries out refining glue to divide dish, divides and is filled on drip pan, for subsequent use.

7, drying glue: get point drip pan installing sizing material and be placed in hot air circulation calorstat and carry out drying glue, temperature controls at 115 ± 5 DEG C, heats 20-40 minute (as 30 minutes);

8, gluing: connected by elastical cloth on coating unit, puts the sizing material be baked on coating unit front truck base plate, carries out gluing and obtain ointment cloth;

What gluing adopted is RYTJZ-B type hot pressing coating machine group, first elastical cloth is connected on coating unit, gluing unit front truck base plate is preheated to 110 DEG C ± 5 DEG C, and scraper is preheated to 110 ± 5 DEG C, and roller is preheated to 75 DEG C ± 5 DEG C, suitable winding tension is up and down set, scope 0.2N ~ 0.4N, regulates wire velocity control at 4 ~ 7 ms/min, then is put by the sizing material be baked in baking oven on coating unit front truck base plate, start gluing, coating unit overhead temperature regulating arranges and is no more than 20 DEG C.

9, rolling is cut off: during every rolling 60m, take off ointment cloth, lain in by ointment cloth on cutting bed and carry out cutting;

Suspend during every rolling 60m, take off ointment cloth, heavily change spool, then drive to continue rolling.After rolling, ointment cloth is lain on cutting bed, after fixing machine sections position spiral shell button, make marks from left to right, cutting of starting shooting after confirming the locking of each position.

10, cut into slices: the ointment yardage roll after the section of cutting is put on microtome, carries out section and make carrier.

Microtome adopts DDQJ-C type one side punching microtome, puts on microtome, start punching by the ointment yardage roll after the gluing section of cutting, and lid lining release paper, cuts into and correspond to 4cm × 6.5cm patch sheet.

Finally carrier and the combination of medicine gauze, sterilization, finally with the plastic sheeting lid lining of sterilization, cuts, to obtain final product.

Medicine prepared by the present invention can be used for treatment dissipating blood stasis, detumescence, hemostasis and pain-relieving.And for shallow table wound, protect from infection and promote wound healing.

Should be understood that, application of the present invention is not limited to above-mentioned citing, for those of ordinary skills, can be improved according to the above description or convert, and all these improve and convert the protection domain that all should belong to claims of the present invention.

Claims (3)

1. wound healing cream, is characterized in that, by mass parts, comprising:

Ethacridine 2 ~ 5 parts;

Cure-all 1 ~ 3 part;

Essence 180 ~ 220 parts, gauze;

Zinc oxide 30 ~ 35 parts;

Colophonium 28 ~ 32 parts;

Rubber 22 ~ 28 parts;

Yellow Vaselin 5 ~ 7 parts;

Lanoline 2 ~ 5 parts;

Paraffin hydrocarbons 0.2 ~ 0.7 part.

2. wound healing cream according to claim 1, is characterized in that, by mass parts, comprising:

Ethacridine 3 parts;

Cure-all 1.5 parts;

Essence 200 parts, gauze;

Zinc oxide 32.5 parts;

Colophonium 29.5 parts;

Rubber 25.5 parts;

Yellow Vaselin 6.5 parts;

Lanoline 3.5 parts;

Paraffin hydrocarbons 0.5 part.

3. a preparation method for wound healing cream as claimed in claim 1, is characterized in that, comprise step:

First ethacridine and cure-all adding distil water are dissolved, after all dissolving, add smart gauze and soak 8 hours, make leaching medicine even, take out, dry, cut, folded bar obtains medicine gauze;

By rubber through refining glue, immersion, playing glue process, break into cream slurry, filter, leave standstill, be coated with cream, cut, make carrier;

Carrier and the combination of medicine gauze, sterilization, finally with the plastic sheeting lid lining of sterilization, cuts, to obtain final product.