CN102218129A - New drug delivery system of gynaecologic panchrest plaster - Google Patents
New drug delivery system of gynaecologic panchrest plaster Download PDFInfo
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- CN102218129A CN102218129A CN 201010252775 CN201010252775A CN102218129A CN 102218129 A CN102218129 A CN 102218129A CN 201010252775 CN201010252775 CN 201010252775 CN 201010252775 A CN201010252775 A CN 201010252775A CN 102218129 A CN102218129 A CN 102218129A
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- drug delivery
- gynaecologic
- delivery system
- new drug
- medicine
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- Medicines Containing Plant Substances (AREA)
- Cosmetics (AREA)
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Abstract
The invention relates to a new drug delivery system of gynaecologic panchrest plaster. The system consists of 0.16-0.36kg of dimethyl sulfone, 0.13-0.33kg of eucalyptus oil, 5.68-7.68kg of rubber, 0.6-1.5kg of vaseline, 0.30-1.00kg of lanolin, 7.8-9.8kg of zinc oxide, 0.28-0.48kg of liquid paraffin, 5.0-7.0kg of rosin and 5.33kg of traditional Chinese medicine extract. With the drug delivery system of the above prescription for drug loading, the gynaecologic panchrest plaster produced has consistent color, smooth cut opening and good drug delivery effect, with the incidence rate of skin irritation and anaphylaxis reduced to less than 0.8%.
Description
Technical field
The present invention relates to the new medicine-releasing system of a kind of universal gynecologic cream.
Background technology
Universal gynecologic cream is the agent of pure Chinese medicine external plaster, by Lignum Sappan, Radix Ampelopsis, etc. 17 flavor Chinese medicines form.The said preparation prescription is rigorous rationally, determined curative effect, has dispelling cold by warming the meridian, blood circulation promoting and blood stasis dispelling, regulating QI to relieve pain effect after each medicine combination in the side.Be used for the menoxenia abdominal pain in menstruation that the cold womb stasis causes, the cold amenorrhea of abdomen, lumbago belt is inferior.
The flavour of a drug of universal gynecologic cream are formed science, rationally, meet dispelling cold by warming the meridian, blood circulation promoting and blood stasis dispelling, and regulating QI to relieve pain Chinese medicine theory, but because emplastrum medicine carrying matrix design unreasonable will be unfavorable for the release of medicine and increase the irritant reaction of medication place skin.For this reason.Designed the new medicine-releasing system of a kind of universal gynecologic cream.
Summary of the invention
The prescription of the medicine-releasing system that universal gynecologic cream is new (30,000 subsides amount) composed as follows:
Dimethylsulfone 0.16～0.36kg, Oleum Eucalypti 0.13～0.33kg, rubber 5.68～7.68kg, vaseline 0.6～1.5kg, lanoline 0.30～1.00kg, zinc oxide 7.8～9.8kg, liquid paraffin 0.28～0.48kg, Colophonium 5.0～7.0kg, Chinese medical concrete 5.33kg,
Use the medicine-releasing system medicine carrying of above-mentioned prescription, the unilateral color and luster unanimity of the universal gynecologic cream that makes, it is smooth to cut the hole, and release is respond well, and skin irritation and anaphylaxis incidence rate are reduced to below 0.8%.
The specific embodiment
[prescription]
Chinese medical concrete 5.33kg
Dimethylsulfone 0.266kg
Oleum Eucalypti 0.23kg
Rubber 6.857kg
Vaseline 1.23kg
Lanoline 0.769kg
Zinc oxide 8.842kg
Liquid paraffin 0.385kg
Colophonium 5.96kg
Make 30000 cards
[method for making]
1. system extractum:
Get the recipe quantity Chinese crude drug of respectively distinguishing the flavor of, after pre-treatments such as washing, add 95% ethanol extraction, reclaim ethanol, concentrate, drying, extractum, standby.
2. glue:
Adjust the rubber mixing machine roll spacing, machining, it is netted or laminar that blob of viscose is pressed into.
3. mix glue:
Rubber after will broken glue drops in the kneader and stirs, mix, to all adjuvants, the mixing do not had in the prescriptions such as adding dimethylsulfone behind the micelle, to the rubber mixing.Chinese medical concrete is added in the kneader mixing.
4. drying glue:
After being warming up to 80-105 ℃ in the baking oven, sending into and refined glue cream, heating.Dry by the fire to glue cream and be cellular or soft shape.
5. coating:
Hot calender coating machine upper blade is preheated to 80-110 ℃, following heating is preheated to 40-60 ℃, contain offset plate and be preheated to 80-100 ℃, put on elastic force cloth, regulate the spacing of base plate and scraper, the sizing material stand that preheating is good is coated on the cloth cover, check and all begin gluing after normal (glue-spread: 1.6-2.0g/100cm2), require cloth cover smooth, gluing is even, the adhesive plaster of spooling answers degree of tightness suitable, and two ends are neat.
6 sections
The ointment volume that cuts is inserted on the microtome thick stick traveller, section, every width 70mm, it is evenly neat that the punching degree of depth is wanted.
7. pack:
Get the ointment table that is up to the standards from section punching chamber; Get qualified packaging bag from the packaging material temporary room, pack, every packed 4 paste, and put involution on the sealing machine.Require packaging bag enclosing tight, smooth.
Claims (2)
1. medicine-releasing system that universal gynecologic cream is new.
2. the new medicine-releasing system of the described a kind of universal gynecologic cream of claim 1 is characterized in that: in the prescription in per 30000 cards contained principal agent and the weight of adjuvant be dimethylsulfone 0.16～0.36kg, Oleum Eucalypti 0.13～0.33kg, rubber 5.68～7.68kg, vaseline 0.6～1.5kg, lanoline 0.30～1.00kg, zinc oxide 7.8～9.8kg, liquid paraffin 0.28～0.48kg, Colophonium 5.0～7.0kg, Chinese medical concrete 5.33kg.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201010252775 CN102218129A (en) | 2010-08-13 | 2010-08-13 | New drug delivery system of gynaecologic panchrest plaster |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN 201010252775 CN102218129A (en) | 2010-08-13 | 2010-08-13 | New drug delivery system of gynaecologic panchrest plaster |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN102218129A true CN102218129A (en) | 2011-10-19 |
Family
ID=44774999
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN 201010252775 Pending CN102218129A (en) | 2010-08-13 | 2010-08-13 | New drug delivery system of gynaecologic panchrest plaster |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN102218129A (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104873480A (en) * | 2015-05-23 | 2015-09-02 | 王永刚 | Base material for adhesive plaster production through hot-press method, and adhesive plaster preparation method utilizing base material |
| CN107823593A (en) * | 2017-11-21 | 2018-03-23 | 安徽金马药业有限公司 | A kind of universal gynecologic cream and its preparation technology |
| CN112773860A (en) * | 2021-01-18 | 2021-05-11 | 澳邦制药(横琴)有限公司 | Wanying ointment and preparation method thereof |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1368244A (en) * | 2001-02-01 | 2002-09-11 | 杨孟君 | Nano universal gynecologic medicine and its preparing process |
-
2010
- 2010-08-13 CN CN 201010252775 patent/CN102218129A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1368244A (en) * | 2001-02-01 | 2002-09-11 | 杨孟君 | Nano universal gynecologic medicine and its preparing process |
Non-Patent Citations (2)
| Title |
|---|
| 《卫生部颁中药标准》 19971231 中华人民共和国卫生部药典委员会 妇科万应膏 51 1-2 , * |
| 《现代中西医结合杂志》 20070320 刘瑞芝等 妇科万应膏的质量标准研究 1238-1239 1-2 第16卷, 第09期 * |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104873480A (en) * | 2015-05-23 | 2015-09-02 | 王永刚 | Base material for adhesive plaster production through hot-press method, and adhesive plaster preparation method utilizing base material |
| CN104873480B (en) * | 2015-05-23 | 2018-05-04 | 王永刚 | Pressure sintering produces the matrix of rubber ointment and prepares the method for rubber ointment with it |
| CN107823593A (en) * | 2017-11-21 | 2018-03-23 | 安徽金马药业有限公司 | A kind of universal gynecologic cream and its preparation technology |
| CN112773860A (en) * | 2021-01-18 | 2021-05-11 | 澳邦制药(横琴)有限公司 | Wanying ointment and preparation method thereof |
| CN112773860B (en) * | 2021-01-18 | 2022-02-08 | 澳邦制药(横琴)有限公司 | Wanying ointment and preparation method thereof |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| C02 | Deemed withdrawal of patent application after publication (patent law 2001) | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20111019 |