CN109528486A - A kind of self-heating smoke-less moxibustion plaster - Google Patents
A kind of self-heating smoke-less moxibustion plaster Download PDFInfo
- Publication number
- CN109528486A CN109528486A CN201910034320.1A CN201910034320A CN109528486A CN 109528486 A CN109528486 A CN 109528486A CN 201910034320 A CN201910034320 A CN 201910034320A CN 109528486 A CN109528486 A CN 109528486A
- Authority
- CN
- China
- Prior art keywords
- folium artemisiae
- layer
- artemisiae argyi
- ointment
- self
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000010438 heat treatment Methods 0.000 title claims abstract description 59
- 239000011505 plaster Substances 0.000 title claims description 38
- 239000002674 ointment Substances 0.000 claims abstract description 72
- 230000002269 spontaneous effect Effects 0.000 claims abstract description 34
- 239000000463 material Substances 0.000 claims abstract description 21
- 238000013022 venting Methods 0.000 claims abstract description 20
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 17
- 239000004831 Hot glue Substances 0.000 claims abstract description 14
- 239000011347 resin Substances 0.000 claims abstract description 14
- 229920005989 resin Polymers 0.000 claims abstract description 14
- 239000000017 hydrogel Substances 0.000 claims abstract description 12
- 238000010792 warming Methods 0.000 claims abstract description 12
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims abstract description 9
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 claims abstract description 9
- 229910052799 carbon Inorganic materials 0.000 claims abstract description 9
- 229910052902 vermiculite Inorganic materials 0.000 claims abstract description 9
- 235000019354 vermiculite Nutrition 0.000 claims abstract description 9
- 239000010455 vermiculite Substances 0.000 claims abstract description 9
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims abstract description 6
- 239000000853 adhesive Substances 0.000 claims abstract description 6
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 claims abstract description 6
- 229910052782 aluminium Inorganic materials 0.000 claims abstract description 6
- 239000011888 foil Substances 0.000 claims abstract description 6
- 238000000926 separation method Methods 0.000 claims abstract description 5
- 239000000284 extract Substances 0.000 claims description 50
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 30
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 24
- 239000000706 filtrate Substances 0.000 claims description 18
- 239000003921 oil Substances 0.000 claims description 16
- 239000000843 powder Substances 0.000 claims description 16
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 12
- 235000019441 ethanol Nutrition 0.000 claims description 12
- 229940116257 pepper extract Drugs 0.000 claims description 9
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 claims description 8
- 239000012528 membrane Substances 0.000 claims description 7
- 239000000203 mixture Substances 0.000 claims description 7
- 229920002725 thermoplastic elastomer Polymers 0.000 claims description 7
- 235000002566 Capsicum Nutrition 0.000 claims description 6
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 claims description 6
- 239000001390 capsicum minimum Substances 0.000 claims description 6
- 238000000605 extraction Methods 0.000 claims description 6
- 239000000341 volatile oil Substances 0.000 claims description 6
- FJKROLUGYXJWQN-UHFFFAOYSA-N 4-hydroxybenzoic acid Chemical class OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 claims description 5
- 239000005995 Aluminium silicate Substances 0.000 claims description 5
- 239000003109 Disodium ethylene diamine tetraacetate Substances 0.000 claims description 5
- ZGTMUACCHSMWAC-UHFFFAOYSA-L EDTA disodium salt (anhydrous) Chemical compound [Na+].[Na+].OC(=O)CN(CC([O-])=O)CCN(CC(O)=O)CC([O-])=O ZGTMUACCHSMWAC-UHFFFAOYSA-L 0.000 claims description 5
- 239000004166 Lanolin Substances 0.000 claims description 5
- 235000012211 aluminium silicate Nutrition 0.000 claims description 5
- UTUUIUQHGDRVPU-UHFFFAOYSA-K aluminum;2-aminoacetate;dihydroxide;hydrate Chemical compound O.[OH-].[OH-].[Al+3].NCC([O-])=O UTUUIUQHGDRVPU-UHFFFAOYSA-K 0.000 claims description 5
- 235000013871 bee wax Nutrition 0.000 claims description 5
- 239000012166 beeswax Substances 0.000 claims description 5
- 239000006071 cream Substances 0.000 claims description 5
- 235000019301 disodium ethylene diamine tetraacetate Nutrition 0.000 claims description 5
- NLYAJNPCOHFWQQ-UHFFFAOYSA-N kaolin Chemical compound O.O.O=[Al]O[Si](=O)O[Si](=O)O[Al]=O NLYAJNPCOHFWQQ-UHFFFAOYSA-N 0.000 claims description 5
- 235000019388 lanolin Nutrition 0.000 claims description 5
- 229940039717 lanolin Drugs 0.000 claims description 5
- 229920001495 poly(sodium acrylate) polymer Polymers 0.000 claims description 5
- 239000008213 purified water Substances 0.000 claims description 5
- NNMHYFLPFNGQFZ-UHFFFAOYSA-M sodium polyacrylate Chemical compound [Na+].[O-]C(=O)C=C NNMHYFLPFNGQFZ-UHFFFAOYSA-M 0.000 claims description 5
- 150000003505 terpenes Chemical class 0.000 claims description 5
- 235000007586 terpenes Nutrition 0.000 claims description 5
- 229940099259 vaseline Drugs 0.000 claims description 5
- AXTGDCSMTYGJND-UHFFFAOYSA-N 1-dodecylazepan-2-one Chemical compound CCCCCCCCCCCCN1CCCCCC1=O AXTGDCSMTYGJND-UHFFFAOYSA-N 0.000 claims description 4
- 229960003639 laurocapram Drugs 0.000 claims description 4
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 claims description 3
- 239000001569 carbon dioxide Substances 0.000 claims description 3
- 229910002092 carbon dioxide Inorganic materials 0.000 claims description 3
- 238000001914 filtration Methods 0.000 claims description 3
- 150000003839 salts Chemical class 0.000 claims description 3
- 238000007873 sieving Methods 0.000 claims description 3
- 238000001256 steam distillation Methods 0.000 claims description 3
- 238000000194 supercritical-fluid extraction Methods 0.000 claims description 3
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims description 2
- 229910052708 sodium Inorganic materials 0.000 claims description 2
- 239000011734 sodium Substances 0.000 claims description 2
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 claims 2
- 240000008574 Capsicum frutescens Species 0.000 claims 2
- 235000005979 Citrus limon Nutrition 0.000 claims 1
- 244000131522 Citrus pyriformis Species 0.000 claims 1
- 244000147568 Laurus nobilis Species 0.000 claims 1
- 235000017858 Laurus nobilis Nutrition 0.000 claims 1
- 235000005212 Terminalia tomentosa Nutrition 0.000 claims 1
- 239000002253 acid Substances 0.000 claims 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 claims 1
- 150000002576 ketones Chemical class 0.000 claims 1
- 229910052757 nitrogen Inorganic materials 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 24
- 238000004519 manufacturing process Methods 0.000 abstract description 6
- 230000008901 benefit Effects 0.000 abstract description 5
- 238000002360 preparation method Methods 0.000 abstract description 4
- 239000002994 raw material Substances 0.000 abstract description 3
- 239000003814 drug Substances 0.000 description 17
- 239000000047 product Substances 0.000 description 14
- 208000024891 symptom Diseases 0.000 description 13
- 229940079593 drug Drugs 0.000 description 11
- 235000010894 Artemisia argyi Nutrition 0.000 description 10
- 244000030166 artemisia Species 0.000 description 10
- 201000010099 disease Diseases 0.000 description 6
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 6
- 230000006872 improvement Effects 0.000 description 6
- 238000000034 method Methods 0.000 description 6
- 239000011159 matrix material Substances 0.000 description 5
- 241000208293 Capsicum Species 0.000 description 4
- 239000004615 ingredient Substances 0.000 description 4
- DTGKSKDOIYIVQL-QXFUBDJGSA-N (-)-borneol Chemical compound C1C[C@]2(C)[C@H](O)C[C@H]1C2(C)C DTGKSKDOIYIVQL-QXFUBDJGSA-N 0.000 description 3
- 229930006703 (-)-borneol Natural products 0.000 description 3
- 206010037660 Pyrexia Diseases 0.000 description 3
- 238000010521 absorption reaction Methods 0.000 description 3
- 238000001467 acupuncture Methods 0.000 description 3
- 239000000499 gel Substances 0.000 description 3
- 230000008569 process Effects 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- 238000002560 therapeutic procedure Methods 0.000 description 3
- 238000002485 combustion reaction Methods 0.000 description 2
- 230000000857 drug effect Effects 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 239000004744 fabric Substances 0.000 description 2
- 230000036571 hydration Effects 0.000 description 2
- 238000006703 hydration reaction Methods 0.000 description 2
- 239000004745 nonwoven fabric Substances 0.000 description 2
- 230000035807 sensation Effects 0.000 description 2
- 230000007958 sleep Effects 0.000 description 2
- 230000000638 stimulation Effects 0.000 description 2
- 206010067484 Adverse reaction Diseases 0.000 description 1
- 206010012735 Diarrhoea Diseases 0.000 description 1
- 208000005171 Dysmenorrhea Diseases 0.000 description 1
- 206010013935 Dysmenorrhoea Diseases 0.000 description 1
- 235000002918 Fraxinus excelsior Nutrition 0.000 description 1
- 208000002193 Pain Diseases 0.000 description 1
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 description 1
- 206010053615 Thermal burn Diseases 0.000 description 1
- 210000001015 abdomen Anatomy 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 230000006838 adverse reaction Effects 0.000 description 1
- 239000005030 aluminium foil Substances 0.000 description 1
- 239000002956 ash Substances 0.000 description 1
- 230000004888 barrier function Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000000919 ceramic Substances 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 208000019902 chronic diarrheal disease Diseases 0.000 description 1
- 235000019504 cigarettes Nutrition 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 230000032798 delamination Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 238000002651 drug therapy Methods 0.000 description 1
- 230000007613 environmental effect Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 238000010304 firing Methods 0.000 description 1
- 239000003292 glue Substances 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 239000012943 hotmelt Substances 0.000 description 1
- 229920003063 hydroxymethyl cellulose Polymers 0.000 description 1
- 229940031574 hydroxymethyl cellulose Drugs 0.000 description 1
- 230000008595 infiltration Effects 0.000 description 1
- 238000001764 infiltration Methods 0.000 description 1
- 206010022437 insomnia Diseases 0.000 description 1
- 230000002427 irreversible effect Effects 0.000 description 1
- 239000006210 lotion Substances 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 230000005906 menstruation Effects 0.000 description 1
- 238000000465 moulding Methods 0.000 description 1
- 150000004767 nitrides Chemical class 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 238000000554 physical therapy Methods 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 238000003672 processing method Methods 0.000 description 1
- 238000006479 redox reaction Methods 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 239000000779 smoke Substances 0.000 description 1
- 210000000952 spleen Anatomy 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 229910052613 tourmaline Inorganic materials 0.000 description 1
- 229940070527 tourmaline Drugs 0.000 description 1
- 239000011032 tourmaline Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
- A61H39/00—Devices for locating or stimulating specific reflex points of the body for physical therapy, e.g. acupuncture
- A61H39/06—Devices for heating or cooling such points within cell-life limits
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F7/02—Compresses or poultices for effecting heating or cooling
- A61F7/03—Compresses or poultices for effecting heating or cooling thermophore, i.e. self-heating, e.g. using a chemical reaction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/282—Artemisia, e.g. wormwood or sagebrush
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7046—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds
- A61K9/7053—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising macromolecular compounds obtained by reactions only involving carbon to carbon unsaturated bonds, e.g. polyvinyl, polyisobutylene, polystyrene
- A61K9/7061—Polyacrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
- A61K9/703—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms characterised by shape or structure; Details concerning release liner or backing; Refillable patches; User-activated patches
- A61K9/7038—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer
- A61K9/7076—Transdermal patches of the drug-in-adhesive type, i.e. comprising drug in the skin-adhesive layer the adhesive comprising ingredients of undetermined constitution or reaction products thereof, e.g. rosin or other plant resins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F7/02—Compresses or poultices for effecting heating or cooling
- A61F2007/0203—Cataplasms, poultices or compresses, characterised by their contents; Bags therefor
- A61F2007/0206—Cataplasms, poultices or compresses, characterised by their contents; Bags therefor containing organic solids or fibres
- A61F2007/0207—Plants, dried plants, seeds or fruits
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F7/02—Compresses or poultices for effecting heating or cooling
- A61F2007/0225—Compresses or poultices for effecting heating or cooling connected to the body or a part thereof
- A61F2007/0226—Compresses or poultices for effecting heating or cooling connected to the body or a part thereof adhesive, self-sticking
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F7/00—Heating or cooling appliances for medical or therapeutic treatment of the human body
- A61F7/02—Compresses or poultices for effecting heating or cooling
- A61F2007/0261—Compresses or poultices for effecting heating or cooling medicated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
- A61H2201/00—Characteristics of apparatus not provided for in the preceding codes
- A61H2201/02—Characteristics of apparatus not provided for in the preceding codes heated or cooled
- A61H2201/0207—Characteristics of apparatus not provided for in the preceding codes heated or cooled heated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61H—PHYSICAL THERAPY APPARATUS, e.g. DEVICES FOR LOCATING OR STIMULATING REFLEX POINTS IN THE BODY; ARTIFICIAL RESPIRATION; MASSAGE; BATHING DEVICES FOR SPECIAL THERAPEUTIC OR HYGIENIC PURPOSES OR SPECIFIC PARTS OF THE BODY
- A61H2201/00—Characteristics of apparatus not provided for in the preceding codes
- A61H2201/10—Characteristics of apparatus not provided for in the preceding codes with further special therapeutic means, e.g. electrotherapy, magneto therapy or radiation therapy, chromo therapy, infrared or ultraviolet therapy
- A61H2201/105—Characteristics of apparatus not provided for in the preceding codes with further special therapeutic means, e.g. electrotherapy, magneto therapy or radiation therapy, chromo therapy, infrared or ultraviolet therapy with means for delivering media, e.g. drugs or cosmetics
Abstract
The present invention relates to a kind of self-heating smoke-less moxibustion plasters, are bonded together and are constituted by folium artemisiae argyi ointment layer, back bracket layer and spontaneous heating thermal paste layer from bottom to top, the center of folium artemisiae argyi ointment layer, back bracket layer and spontaneous heating thermal paste layer is on the same line；Spontaneous heating thermal paste layer is placed in the venting bags of circular sky by exothermic material and is constituted, and posts separation layer outside venting bags, exothermic material is made of iron powder, expanded vermiculite, active carbon, Nacl, water-absorbing resins, water；Back bracket layer is double-sided self-adhesive aluminum foil, and self-adhesion face bonds together with spontaneous heating thermal paste layer and folium artemisiae argyi ointment layer；The folium artemisiae argyi ointment layer is made of round separate paper and the ointment being pasted together with round separate paper, ointment is one of hot melt adhesive patch, warming hydrogel patch or round ointment, abundant raw materials of the present invention, production method is simple, preparation easy to produce, at low cost, effect is good, it is the big innovation on moxibustion treatment articles, there is good economic and social benefit.
Description
Technical field
The present invention relates to moxibustion product, especially a kind of self-heating smoke-less moxibustion plaster.
Background technique
Moxa-moxibustion is that the interior disease of one of most ancient and most important therapy and the unique complete set of the mankind is outer inside Chinese medicine
System is controlled, is clinically widely applied always, there are obvious curative effects to a variety of diseases.Moxa-moxibustion is with moxa for main incendiary material,
Certain position or the acupuncture points on the human body that body surface is placed it in after lighting, by the warm stimulation of Chinese mugwort burning and itself drug therapy, thus
Reach the purpose prevented and cured diseases.But traditional puncture is because of factors hampers such as smoke fire burns, ashes scald, cumbersome, low efficiencys
The development of moxa-moxibustion.Many moxibustion products are improved at present, such as stuck paper tube moxibustion sticks (patent No. 201020534103), Chinese mugwort
Moxibustion patch (patent No. 201120573062), moxibustion plaster (patent No. 201220183825,201220316041), infrared therapy
Instrument moxibustion (patent No. 201320829302), moxibustion plaster moxibustion (patent No. 201220316041,201520682362), a kind of Chinese mugwort essence
Oily moxibustion plaster (patent No. 201621048381), a kind of moxibustion plaster (patent No. 201520647129,201520989692,
201620345005) a kind of, patented product of efficiently mild moxibustion plaster (patent No. 201720379615) etc..
Above product all increases on the basis of traditional puncture, improves to some extent, but folium artemisiae argyi medicine in most of product
Perhaps P-Cymene or fuzzy, the heating layer use to the processing method description of folium artemisiae argyi of the single selection folium artemisiae argyi fine powder of nitride layer, moxa
Far-infared ceramic powder or Tourmaline fever powder, these substance calorific values are little, in addition, the folium artemisiae argyi fine powder of addition, with traditional moxa
The chemical substance discharged after burning cannot be equal, meanwhile, single P-Cymene is released after can not representing folium artemisiae argyi burning completely
The active principle put.
Some is shared using moxa layer and essential oil introduced layer, and such as a kind of Novel moxibustion patch and moxa-moxibustion patch combine (patent
Number 201710699838), the moxa layer of the patent introduction, wherein main component is the T-type nonglandular hair of folium artemisiae argyi, can not abundant generation
Table represents effective component in folium artemisiae argyi；
In addition, a kind of make referrals to from moxibustion plaster (patent No. 201720003515) is lighted containing L-Borneol layer, there is one outside the L-Borneol layer
Layer non-woven fabrics air-permeable layer, although non-woven fabrics can breathe freely, L-Borneol is not directly and skin contact, drug absorption will receive limitation；
Equally, one kind, which is begged, also describes heating pack, Chinese mugwort extract and hot melt cream in moxibustion plaster (patent No. 201810755012)
The combination of body, but the patent is placed on lotion is heated in Chinese mugwort extract except drug application packet, due to the nonwoven at the hot melt adhesive back side
Cloth directly contacts the middle drug application packet of internal layer, simultaneously because the barrier action of hot melt adhesive cream, will lead in middle drug application packet it is effective at
Patient skin can not be touched by dividing, so that making the performance of drug effect can have a greatly reduced quality, can not meet the actual needs of moxa-moxibustion.Therefore,
The improvement and innovation of moxibustion product are imperative.
Summary of the invention
For above situation, for the defect for overcoming the prior art, the purpose of the present invention is just to provide a kind of self-heating smoke-less
There is moxibustion plaster folium artemisiae argyi active principle to extract sufficiently, manufacture simple, the abundant advantage of moulding type.It can be effective in use
It solves the problems, such as that moxibustion treatment disease is cumbersome, inconvenient and effect is poor, while there is safety and environmental protection, reduce smog in use process
Adverse effect of the particle to personnel health.
The technical solution that the present invention solves is a kind of self-heating smoke-less moxibustion plaster, by folium artemisiae argyi ointment layer, back from bottom to top
Support layer and spontaneous heating thermal paste layer are bonded together composition, and the center of folium artemisiae argyi ointment layer, back bracket layer and spontaneous heating thermal paste layer is same
On straight line；
The spontaneous heating thermal paste layer is placed in the venting bags of circular sky by exothermic material and is constituted, and posts separation layer outside venting bags,
The exothermic material is by following weight ratio meter: 38~50g of iron powder, 15~25 g of expanded vermiculite, 15~20 g of active carbon, work
2~5 g of industry salt, 1~3 g of water-absorbing resins, 10~25 g of water are made；The venting bags are the circles being sealed to by ventilated membrane；
The back bracket layer is double-sided self-adhesive aluminum foil, and two self-adhesion faces are bonded in one with spontaneous heating thermal paste layer, folium artemisiae argyi ointment layer respectively
It rises；
The folium artemisiae argyi ointment layer can be to be made of round separate paper and the ointment being pasted together with round separate paper, described
Ointment is one of hot melt adhesive patch, warming hydrogel patch or round ointment, and the hot melt adhesive patch is by following weight ratio
Meter: 0.30~0.85g of volatile argyi leaf oil, 2.5~6.0g of folium artemisiae argyi medicinal extract, 10~20g of thermoplastic elastomer, atoleine 3~
15g, 2~5g of terpene resin and 0.01~0.04g of dimethyl sulfoxide are uniformly mixed manufactured thickness 0.2cm~0.4cm, diameter 3.5cm
Circular patch；
The warming hydrogel patch is by following weight ratio meter: volatile argyi leaf oil 0.2-0.65g, folium artemisiae argyi medicinal extract 2.0~5.0
G, 0.01~0.1 g of pepper extract, 5~10 g of Sodium Polyacrylate, 2~6 g of sodium cellulose glycolate, 20~30 g of glycerol,
50~60 g of purified water, 0.01~0.5 g of Dihydroxyaluminium Aminoacetate, 0.05~0.2 g of disodium ethylene diamine tetraacetate, citric acid 0.1~0.5
G, 0.5~2 g of kaolin and 0.01~0.5 g of paraben esters be uniformly mixed made of thickness 0.2cm~0.4cm, diameter 3.5cm
Circular patch；
The circle ointment is the first round ointment or the second round ointment, and the first round ointment is by following weight ratio meter:
0.30~0.85g of volatile argyi leaf oil, 2.5~6.0g of folium artemisiae argyi medicinal extract, 10~20g of beeswax, 3~15g of vaseline, 2~5g of lanolin,
The circle that 2~4g of glycerol and 0.1~0.4g of Laurocapram is uniformly mixed manufactured thickness 0.2cm~0.4cm, diameter 3.5cm is soft
Cream；The round ointment of described second is by following weight ratio meter: 2~4g of folium artemisiae argyi supercritical extract, 2~3g of folium artemisiae argyi fine powder are mixed
Close the round paste of uniformly manufactured thickness 0.2-0.4cm, diameter 3.5cm；
The volatile argyi leaf oil uses extraction by steam distillation, and dry folium artemisiae argyi is added to the water of 10 times of weight, extracts 4h, is collected
Volatile oil；
The folium artemisiae argyi medicinal extract is: taking dry folium artemisiae argyi, the ethyl alcohol that the volumetric concentration 85% of 8 times of weight is added extracts 2h, and filtering obtains the
One filtrate, the ethyl alcohol that the volumetric concentration 85% of 6 times of dry folium artemisiae argyi weight is added in the first filtrate extract 1h, obtain the second filtrate, merge two
Secondary filtrate, be concentrated into 50 DEG C of relative densities be 1.15~1.20 to get；
The pepper extract is: taking dry capsicum, the ethyl alcohol of the volumetric concentration 85% of 6 times of dry capsicum weight, diacolation is added
For 24 hours, collect filtrate, filtrate be concentrated into 50 DEG C of relative densities 1.25~1.30 to get；
The folium artemisiae argyi supercritical extract is: being first ground into folium artemisiae argyi and is all sieved by 24 mesh pharmacopeia and sieved by 65 mesh pharmacopeia
Coarse powder no more than 40% is fitted into carbon dioxide supercritical extraction tank, adds the volume fraction 75% of folium artemisiae argyi weight 5~10%
Ethyl alcohol, set 35~45 DEG C of extractor temperature, 25~40Mpa of extracting pressure, 45~60 DEG C of I temperature of knockout drum, separating pressure 6
~10Mpa after 30~40 DEG C, 4~8Mpa of separating pressure, 1~2h of extraction time of II temperature of knockout drum, passes through knockout drum I respectively
Extract is released with the valve of knockout drum II, merges extract twice, obtains folium artemisiae argyi supercritical extract；
The folium artemisiae argyi fine powder is the powder for all sieving and being no less than by 100 mesh pharmacopeia sieve 95% by 80 mesh pharmacopeia.
Abundant raw materials of the present invention, production method is simple, preparation easy to produce, at low cost, and effect is good, is moxibustion treatment articles
A big innovation on (drug), there is good economic and social benefit.
Detailed description of the invention
Fig. 1 is structural front view of the invention.
Specific embodiment
It elaborates below in conjunction with drawings and examples to specific implementation of the invention.
The present invention in specific implementation, can be provided by following embodiment.
Embodiment 1: a kind of self-heating smoke-less moxibustion plaster of the present invention, by from bottom to top folium artemisiae argyi ointment layer, back bracket layer and from
Hot warm paste layer is bonded together composition, and the center of folium artemisiae argyi ointment layer, back bracket layer and spontaneous heating thermal paste layer is on the same line；
The spontaneous heating thermal paste layer is placed in the venting bags of circular sky by exothermic material and is constituted, and posts separation layer outside venting bags,
The exothermic material is by following weight ratio meter: 38~50g of iron powder, 15~25 g of expanded vermiculite, 15~20 g of active carbon, work
2~5 g of industry salt, 1~3 g of water-absorbing resins, 10~25 g of water are made；The venting bags are the circles being sealed to by ventilated membrane；
The back bracket layer is double-sided self-adhesive aluminum foil, and two self-adhesion faces are bonded in one with spontaneous heating thermal paste layer, folium artemisiae argyi ointment layer respectively
It rises；
The folium artemisiae argyi ointment layer can be to be made of round separate paper and the ointment being pasted together with round separate paper, described
Ointment is one of hot melt adhesive patch, warming hydrogel patch or round ointment, and the hot melt adhesive patch is by following weight ratio
Meter: 0.30~0.85g of volatile argyi leaf oil, 2.5~6.0g of folium artemisiae argyi medicinal extract, 10~20g of thermoplastic elastomer, atoleine 3~
15g, 2~5g of terpene resin and 0.01~0.04g of dimethyl sulfoxide are uniformly mixed manufactured thickness 0.2cm~0.4cm, diameter 3.5cm
Circular patch；
The warming hydrogel patch is by following weight ratio meter: volatile argyi leaf oil 0.2-0.65g, folium artemisiae argyi medicinal extract 2.0~5.0
G, 0.01~0.1 g of pepper extract, 5~10 g of Sodium Polyacrylate, 2~6 g of sodium cellulose glycolate, 20~30 g of glycerol,
50~60 g of purified water, 0.01~0.5 g of Dihydroxyaluminium Aminoacetate, 0.05~0.2 g of disodium ethylene diamine tetraacetate, citric acid 0.1~0.5
G, 0.5~2 g of kaolin and 0.01~0.5 g of paraben esters be uniformly mixed made of thickness 0.2cm~0.4cm, diameter 3.5cm
Circular patch；
The circle ointment is the first round ointment or the second round ointment, and the first round ointment is by following weight ratio meter:
0.30~0.85g of volatile argyi leaf oil, 2.5~6.0g of folium artemisiae argyi medicinal extract, 10~20g of beeswax, 3~15g of vaseline, 2~5g of lanolin,
The circle that 2~4g of glycerol and 0.1~0.4g of Laurocapram is uniformly mixed manufactured thickness 0.2cm~0.4cm, diameter 3.5cm is soft
Cream；The round ointment of described second is by following weight ratio meter: 2~4g of folium artemisiae argyi supercritical extract, 2~3g of folium artemisiae argyi fine powder are mixed
Close the round paste of uniformly manufactured thickness 0.2-0.4cm, diameter 3.5cm；
The volatile argyi leaf oil uses extraction by steam distillation, and dry folium artemisiae argyi is added to the water of 10 times of weight, extracts 4h, is collected
Volatile oil；
The folium artemisiae argyi medicinal extract is: taking dry folium artemisiae argyi, the ethyl alcohol that the volumetric concentration 85% of 8 times of weight is added extracts 2h, and filtering obtains the
One filtrate, the ethyl alcohol that the volumetric concentration 85% of 6 times of dry folium artemisiae argyi weight is added in the first filtrate extract 1h, obtain the second filtrate, merge two
Secondary filtrate, be concentrated into 50 DEG C of relative densities be 1.15~1.20 to get；
The pepper extract is: taking dry capsicum, the ethyl alcohol of the volumetric concentration 85% of 6 times of dry capsicum weight, diacolation is added
For 24 hours, collect filtrate, filtrate be concentrated into 50 DEG C of relative densities 1.25~1.30 to get；
The folium artemisiae argyi supercritical extract is: being first ground into folium artemisiae argyi and is all sieved by 24 mesh pharmacopeia and sieved by 65 mesh pharmacopeia
Coarse powder no more than 40% is fitted into carbon dioxide supercritical extraction tank, adds the volume fraction 75% of folium artemisiae argyi weight 5~10%
Ethyl alcohol, set 35~45 DEG C of extractor temperature, 25~40Mpa of extracting pressure, 45~60 DEG C of I temperature of knockout drum, separating pressure 6
~10Mpa after 30~40 DEG C, 4~8Mpa of separating pressure, 1~2h of extraction time of II temperature of knockout drum, passes through knockout drum I respectively
Extract is released with the valve of knockout drum II, merges extract twice, obtains folium artemisiae argyi supercritical extract；
The folium artemisiae argyi fine powder is the powder for all sieving and being no less than by 100 mesh pharmacopeia sieve 95% by 80 mesh pharmacopeia.
Embodiment 2: a kind of self-heating smoke-less moxibustion plaster of the present invention, by folium artemisiae argyi ointment layer 5,6 and of back bracket layer from bottom to top
Spontaneous heating thermal paste layer 7 is bonded together composition, and the center of folium artemisiae argyi ointment layer 5, back bracket layer 6 and spontaneous heating thermal paste layer 7 is the same as always
On line；The spontaneous heating thermal paste layer 7 is placed in venting bags by exothermic material to be constituted, and the exothermic material is by following weight ratio meter
: iron powder 39g, expanded vermiculite 17.8g, 16.5 g of active carbon, 19.7 g system of Nacl 4.5g, 2.5 g of water-absorbing resins and water
At；The venting bags 1 are the circles being sealed to by ventilated membrane；Other are the same as embodiment 1.
Embodiment 3: a kind of self-heating smoke-less moxibustion plaster of the present invention, by folium artemisiae argyi ointment layer 5,6 and of back bracket layer from bottom to top
Spontaneous heating thermal paste layer 7 is bonded together composition, and the center of folium artemisiae argyi ointment layer 5, back bracket layer 6 and spontaneous heating thermal paste layer 7 is the same as always
On line；The spontaneous heating thermal paste layer 7 is placed in venting bags by exothermic material to be constituted, and the exothermic material is by following weight ratio meter
: iron powder 45g, expanded vermiculite 15.8g, 18 g of active carbon, Nacl 2.5g, water-absorbing resins 1.5 g and water 17.2g are made；
The venting bags 1 are the circles being sealed to by ventilated membrane；Other are the same as embodiment 1.
Embodiment 4: a kind of self-heating smoke-less moxibustion plaster of the present invention, the hot melt adhesive patch is by following weight ratio meter: Chinese mugwort
Leaf volatile oil 0.65g, folium artemisiae argyi medicinal extract 2.8g, thermoplastic elastomer 10g, atoleine 3g, terpene resin 2g and dimethyl sulfoxide 0.02g
The circular patch of thickness 0.2cm, diameter 3.5cm made of being uniformly mixed；Other are the same as embodiment 1.
Embodiment 5: a kind of self-heating smoke-less moxibustion plaster of the present invention, the warming hydrogel patch is by following weight ratio meter
: volatile argyi leaf oil 0.65g, 2.8 g of folium artemisiae argyi medicinal extract, pepper extract 0.04g, 5.4 g of Sodium Polyacrylate, hydroxymethyl cellulose
Sodium 1.5g, glycerol 15g, 28.7 g of purified water, 0.05 g of Dihydroxyaluminium Aminoacetate, 0.1 g of disodium ethylene diamine tetraacetate, 0.1 g of citric acid,
2 g of kaolin and 0.05 g of paraben esters is uniformly mixed the circular patch of manufactured thickness 0.3cm, diameter 3.5cm；Other are the same as implementation
Example 1.
Embodiment 6: a kind of self-heating smoke-less moxibustion plaster of the present invention, the circle ointment is by following weight ratio meter: Chinese mugwort
Leaf volatile oil 0.65g, folium artemisiae argyi medicinal extract 2.8g, beeswax 16g, vaseline 12g, lanolin 2g, glycerol 2g and Laurocapram 0.2g
The round ointment of thickness 0.2cm, diameter 3.5cm made of being uniformly mixed；Other are the same as embodiment 1.
The present invention sufficiently extracts effective component in folium artemisiae argyi in the case where not using open firing, and not merely using Chinese mugwort
Suede prepares plaster or round ointment further according to transdermal drag delivery, meanwhile, fever is made using chemical heat release principle and is carried
Body, and the two is combined, both realize the effect of open fire moxa-moxibustion, meanwhile, safe ready in use process improves in use
Experience.
It can be seen from the above, a kind of self-heating smoke-less moxibustion plaster of the present invention, back bracket layer use double-sided self-adhesive aluminum foil, can both glue
Attached folium artemisiae argyi ointment layer, while it can also be used as heat-conducting layer, discharge the temperature of heating layer rapidly and uniformly, ointment layer itself has
Adhesiveness is pasted on double-sided self-adhesive aluminum foil, in use, by the separation layer of spontaneous heating thermal paste layer, the separate paper of folium artemisiae argyi ointment layer
It tears, folium artemisiae argyi ointment layer of the invention, which is clung to the body, needs the position of moxa-moxibustion, and folium artemisiae argyi ointment layer has been sufficiently reserved folium artemisiae argyi medicine
Effect ingredient in material is a kind of curative effect of self-heating smoke-less moxibustion plaster, has established material base；Spontaneous heating thermal paste layer is Chinese mugwort
Leaf ointment provides heat, plays its thermogenetic effect, plays the same tune on different musical instruments with the combustion of moxa-moxibustion；Self-heating smoke-less moxibustion plaster product makes
With conveniently, safely, effectively, meet demand of the modern to physiotherapy products.
Spontaneous heating thermal paste layer chinese raw materials iron powder, active carbon, expanded vermiculite, Nacl, water-absorbing resins and water of the present invention
Redox reaction release heat occurs loaded on being contacted in venting bags with air, provides heat for folium artemisiae argyi ointment layer, it is entire to generate heat
Process occurs without combustion phenomena, does not generate any smog, compared with traditional puncture, solves the stimulation of Chinese mugwort cigarette, pollutes asking for air
Topic；Folium artemisiae argyi ointment remains folium artemisiae argyi crude drug the effect of property ingredient, and folium artemisiae argyi ointment is used alone or cooperates with other materials, such as adopts
Use thermoplastic elastomer as matrix, the manufactured hot melt adhesive product in conjunction with Folium Artemisiae Argyi extract, it is excellent that product sticks viscosity；In addition,
Hydrophilic matrix in warming hydrogel patch generates good hydration to skin, is conducive to drug absorption, and warming agent
It is volatilized and is discharged by high molecular weight hydrophilic gel, generate warm sensation.Product of the present invention has preparation convenient, and speed of production is fast,
Quick solidifying, ointment specification is easy to control, free of contamination advantage in production process；It sticks comfortably, is easy to carry about with one.
The present invention is using spontaneous thermal technology, and a kind of Novel moxibustion patch that Folium Artemisiae Argyi extract is used in combination with warm paste makes
It is safely and effectively, easy to carry with convenience, meet modern Man's Demands.By Folium Artemisiae Argyi extract directly using or be made Hot melt adhesive plaster
Piece, hydrogel patch or round ointment, not only can guarantee that properties of product were stablized, but also can control the specification of acupoint plaster needs, while
It can reach and stick comfortable effect, this is the big innovation on moxibustion plaster.
The present invention is applied and is tested on the spot, the temperature that spontaneous heating thermal paste layer can make moxa-moxibustion patch of the present invention reach 40-44 DEG C,
It is very beneficial for the performance of medicine effect, and is conducive to the infiltration to acupuncture point, improve curative effect, uses comfortable, conveniently, safely, performance
Reliable and stable, relevant information is as follows:
1, Shenmen point and Anmian point are sticked using moxibustion plaster of the present invention, and cooperated caused by patch XINYU acupoint treatment heart spleen virtual loss not
It sleeps, after, user is not easy to fall asleep or the symptom of sleep but easy to wake is substantially reduced, and therapeutic effect is good.Totally 76 patients, wherein
Completely disappear cured person 41 of symptom, have clear improvement effective person 28 of symptom, mitigated responder 7 of symptom,
Total effective rate 100%.Except 2 severes are insomnia in addition to patient procedure is more than 4 weeks, remaining patient procedure's longest 12 days is most 3 days short；
2, Sanyinjiao, middle pole He dysmenorrhea caused by tri- acupoint therapy cold-evil of Ci Liao are sluggish, patch are sticked using moxibustion plaster of the present invention
After applying treatment, patient's blockage of menstruation, the symptoms such as few abdomen pain gradually mitigate, and general curative effect is good.Totally 53 patients, wherein symptom
The cured person completely disappeared 19, have clear improvement effective person 28 of symptom, mitigated responder 6 of symptom always have
Efficiency 100%.It is course for the treatment of longest 15 days, most 3 days short；
3, chronic diarrhea caused by TIANSHU acupoint, point st 36, Pishu Points treatment deficiency-weakness of spleen-QI is sticked using moxibustion plaster of the present invention, taken
Good result was obtained, totally 61 patients, wherein completely disappear cured person 29 of symptom, the effective person 27 that symptom has clear improvement
Example, mitigated responder 5 of symptom, total effective rate 100%.It is course for the treatment of longest 16 days, most 5 days short.
The above-mentioned limited amount case only provided, but from these cases it is on probation in, foot is it can be seen that acupoint plaster of the present invention
Curative effect it is very good, in only test, symptom has different degrees of an improvement or improvement, and up to 100%, this shows effective percentage
Product of the present invention curative effect is stable, reliable, and has not issued any adverse reaction in trying out, it was demonstrated that drug safety, and to it
He is treated at disease using moxibustion plaster of the present invention, in limited treatment case, also achieves identical or similar treatment
Effect will not enumerate, it was demonstrated that there is the moxibustion plaster very strong clinical practice application value to have compared with prior art
Advantageous effects following prominent:
1, heating layer uses spontaneous thermal technology, and heating temperature and fever time are controllable.Research shows that: 44 DEG C are 6 hours continuous
It can make skin that irreversible damage occur, above to ensure safe medication, the highest skin that warm paste provides in the moxibustion acupuncture point sticker
Skin temperature should be not higher than 44 DEG C, the duration ± 10 minutes 2 hours, sufficient heat is provided for folium artemisiae argyi ointment, guarantees drug effect
It plays.
2, folium artemisiae argyi ointment remains folium artemisiae argyi crude drug the effect of property ingredient to greatest extent, meanwhile, standardize in quality, is
The curative effect of self-heating smoke-less moxibustion plaster establishes material base.
3, hot melt adhesive patch is made in Folium Artemisiae Argyi extract in conjunction with thermoplastic elastomer, and both effectiveness ingredient performance is stablized, and matrix applies
Cloth is relatively thin, and release is big, while having preparation convenient, and application rate is fast, quick solidifying, and ointment specification is easy to control, in production process
It is pollution-free.
4, Folium Artemisiae Argyi extract is in conjunction with hydrophilic matrix, based on environment-friendly type novel high polymer hydrophilic gel, is added
Warming hydrogel patch is made in pepper extract, is discharged by high molecular weight hydrophilic gel, warm sensation is generated, with controlling for moxa-moxibustion
Treatment effect matches.Hydrophilic matrix generates good hydration to skin, is conducive to drug ingedient absorption.
5, folium artemisiae argyi ointment is rounded, and diameter 3.5cm and Chinese medicine acupoint combine, with strong points, the treatment with traditional puncture
Mechanism close to.
6, the delamination of aluminium foil back can closely connect folium artemisiae argyi ointment layer and spontaneous heating thermal paste layer, and when use can be with Quick uniform
It is thermally conductive.
7, using safe, good effect, in existing experiment case, effective percentage is that As the medicine took effect, the symptoms lessened or disease is light up to 100%,
And it is without side-effects, it is the big innovation on moxibustion product, there is good economic and social benefit.
Claims (6)
1. a kind of self-heating smoke-less moxibustion plaster, it is characterized in that: by folium artemisiae argyi ointment layer, back bracket layer and spontaneous heating warm paste from bottom to top
Layer is bonded together composition, and the center of folium artemisiae argyi ointment layer, back bracket layer and spontaneous heating thermal paste layer is on the same line；
The spontaneous heating thermal paste layer is placed in the venting bags of circular sky by exothermic material and is constituted, and posts separation layer outside venting bags,
The exothermic material is by following weight ratio meter: 38~50g of iron powder, 15~25 g of expanded vermiculite, 15~20 g of active carbon, work
2~5 g of industry salt, 1~3 g of water-absorbing resins, 10~25 g of water are made；The venting bags are the circles being sealed to by ventilated membrane；
The back bracket layer is double-sided self-adhesive aluminum foil, and two self-adhesion faces are bonded in one with spontaneous heating thermal paste layer, folium artemisiae argyi ointment layer respectively
It rises；
The folium artemisiae argyi ointment layer can be to be made of round separate paper and the ointment being pasted together with round separate paper, described
Ointment is one of hot melt adhesive patch, warming hydrogel patch or round ointment, and the hot melt adhesive patch is by following weight ratio
Meter: 0.30~0.85g of volatile argyi leaf oil, 2.5~6.0g of folium artemisiae argyi medicinal extract, 10~20g of thermoplastic elastomer, atoleine 3~
15g, 2~5g of terpene resin and 0.01~0.04g of dimethyl sulfoxide are uniformly mixed manufactured thickness 0.2cm~0.4cm, diameter 3.5cm
Circular patch；
The warming hydrogel patch is by following weight ratio meter: volatile argyi leaf oil 0.2-0.65g, folium artemisiae argyi medicinal extract 2.0~5.0
G, 0.01~0.1 g of pepper extract, 5~10 g of Sodium Polyacrylate, 2~6 g of sodium cellulose glycolate, 20~30 g of glycerol,
50~60 g of purified water, 0.01~0.5 g of Dihydroxyaluminium Aminoacetate, 0.05~0.2 g of disodium ethylene diamine tetraacetate, citric acid 0.1~0.5
G, 0.5~2 g of kaolin and 0.01~0.5 g of paraben esters be uniformly mixed made of thickness 0.2cm~0.4cm, diameter 3.5cm
Circular patch；
The circle ointment is the first round ointment or the second round ointment, and the first round ointment is by following weight ratio meter:
0.30~0.85g of volatile argyi leaf oil, 2.5~6.0g of folium artemisiae argyi medicinal extract, 10~20g of beeswax, 3~15g of vaseline, 2~5g of lanolin,
The circle that 2~4g of glycerol and 0.1~0.4g of Laurocapram is uniformly mixed manufactured thickness 0.2cm~0.4cm, diameter 3.5cm is soft
Cream；The round ointment of described second is by following weight ratio meter: 2~4g of folium artemisiae argyi supercritical extract, 2~3g of folium artemisiae argyi fine powder are mixed
Close the round paste of uniformly manufactured thickness 0.2-0.4cm, diameter 3.5cm；
The volatile argyi leaf oil uses extraction by steam distillation, and dry folium artemisiae argyi is added to the water of 10 times of weight, extracts 4h, is collected
Volatile oil；
The folium artemisiae argyi medicinal extract is: taking dry folium artemisiae argyi, the ethyl alcohol that the volumetric concentration 85% of 8 times of weight is added extracts 2h, and filtering obtains the
One filtrate, the ethyl alcohol that the volumetric concentration 85% of 6 times of dry folium artemisiae argyi weight is added in the first filtrate extract 1h, obtain the second filtrate, merge two
Secondary filtrate, be concentrated into 50 DEG C of relative densities be 1.15~1.20 to get；
The pepper extract is: taking dry capsicum, the ethyl alcohol of the volumetric concentration 85% of 6 times of dry capsicum weight, diacolation is added
For 24 hours, collect filtrate, filtrate be concentrated into 50 DEG C of relative densities 1.25~1.30 to get；
The folium artemisiae argyi supercritical extract is: being first ground into folium artemisiae argyi and is all sieved by 24 mesh pharmacopeia and sieved by 65 mesh pharmacopeia
Coarse powder no more than 40% is fitted into carbon dioxide supercritical extraction tank, adds the volume fraction 75% of folium artemisiae argyi weight 5~10%
Ethyl alcohol, set 35~45 DEG C of extractor temperature, 25~40Mpa of extracting pressure, 45~60 DEG C of I temperature of knockout drum, separating pressure 6
~10Mpa after 30~40 DEG C, 4~8Mpa of separating pressure, 1~2h of extraction time of II temperature of knockout drum, passes through knockout drum I respectively
Extract is released with the valve of knockout drum II, merges extract twice, obtains folium artemisiae argyi supercritical extract；
The folium artemisiae argyi fine powder is the powder for all sieving and being no less than by 100 mesh pharmacopeia sieve 95% by 80 mesh pharmacopeia.
2. self-heating smoke-less moxibustion plaster according to claim 1, it is characterized in that: by folium artemisiae argyi ointment layer 5, back from bottom to top
Support layer 6 and spontaneous heating thermal paste layer 7 are bonded together composition, and the center of folium artemisiae argyi ointment layer 5, back bracket layer 6 and spontaneous heating thermal paste layer 7 exists
On same straight line；The spontaneous heating thermal paste layer 7 is placed in venting bags by exothermic material to be constituted, and the exothermic material is by following heavy
Amount is than meter: iron powder 39g, expanded vermiculite 17.8g, 16.5 g of active carbon, Nacl 4.5g, 2.5 g of water-absorbing resins and water
19.7 g is made；The venting bags 1 are the circles being sealed to by ventilated membrane.
3. self-heating smoke-less moxibustion plaster according to claim 1, it is characterized in that: by folium artemisiae argyi ointment layer 5, back from bottom to top
Support layer 6 and spontaneous heating thermal paste layer 7 are bonded together composition, and the center of folium artemisiae argyi ointment layer 5, back bracket layer 6 and spontaneous heating thermal paste layer 7 exists
On same straight line；The spontaneous heating thermal paste layer 7 is placed in venting bags by exothermic material to be constituted, and the exothermic material is by following heavy
Amount is than meter: iron powder 45g, expanded vermiculite 15.8g, 18 g of active carbon, Nacl 2.5g, water-absorbing resins 1.5 g and water 17.2g
It is made；The venting bags 1 are the circles being sealed to by ventilated membrane.
4. self-heating smoke-less moxibustion plaster according to claim 1, it is characterized in that: the hot melt adhesive patch is by following weight ratio
Meter: volatile argyi leaf oil 0.65g, folium artemisiae argyi medicinal extract 2.8g, thermoplastic elastomer 10g, atoleine 3g, terpene resin 2g and diformazan are sub-
Sulfone 0.02g is uniformly mixed the circular patch of manufactured thickness 0.2cm, diameter 3.5cm.
5. self-heating smoke-less moxibustion plaster according to claim 1, it is characterized in that: the warming hydrogel patch is by following
Weight ratio meter: volatile argyi leaf oil 0.65g, 2.8 g of folium artemisiae argyi medicinal extract, pepper extract 0.04g, 5.4 g of Sodium Polyacrylate, hydroxyl first
Base sodium cellulosate 1.5g, glycerol 15g, 28.7 g of purified water, 0.05 g of Dihydroxyaluminium Aminoacetate, 0.1 g of disodium ethylene diamine tetraacetate, lemon
0.1 g of acid, 2 g of kaolin and 0.05 g of paraben esters are uniformly mixed the circular patch of manufactured thickness 0.3cm, diameter 3.5cm.
6. self-heating smoke-less moxibustion plaster according to claim 1, it is characterized in that: the circle ointment is by following weight ratio
Meter: volatile argyi leaf oil 0.65g, folium artemisiae argyi medicinal extract 2.8g, beeswax 16g, vaseline 12g, lanolin 2g, glycerol 2g and laurel nitrogen are tall and erect
Ketone 0.2g is uniformly mixed the round ointment of manufactured thickness 0.2cm, diameter 3.5cm.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910034320.1A CN109528486A (en) | 2019-01-15 | 2019-01-15 | A kind of self-heating smoke-less moxibustion plaster |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910034320.1A CN109528486A (en) | 2019-01-15 | 2019-01-15 | A kind of self-heating smoke-less moxibustion plaster |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN109528486A true CN109528486A (en) | 2019-03-29 |
Family
ID=65834928
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910034320.1A Pending CN109528486A (en) | 2019-01-15 | 2019-01-15 | A kind of self-heating smoke-less moxibustion plaster |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN109528486A (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110693275A (en) * | 2019-10-23 | 2020-01-17 | 广州秋草堂健康科技有限公司 | Meridian-dredging pain-relieving neck warming pillow |
| CN111214595A (en) * | 2020-02-27 | 2020-06-02 | 郑州爱博尔医疗设备有限公司 | Production method of hot compress wax mud block |
| CN112138063A (en) * | 2020-08-05 | 2020-12-29 | 北京国人御康中医疑难病研究院(普通合伙) | Preparation method of energy moxibustion |
| CN114470145A (en) * | 2022-01-25 | 2022-05-13 | 河北化工医药职业技术学院 | Warm moxibustion type gel plaster for relieving pain of bone diseases and preparation method thereof |
| CN116712324A (en) * | 2023-04-27 | 2023-09-08 | 云南郑保制药有限公司 | Notoginseng moxibustion plaster |
Citations (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1611289A (en) * | 2003-10-30 | 2005-05-04 | 华中科技大学同济医学院附属同济医院 | Supercritical carbon dioxide mugwort active substance extracting method |
| CN101637189A (en) * | 2009-08-21 | 2010-02-03 | 安徽神健生物工程有限公司 | Compound traditional Chinese medicine disinfection solution and preparation method thereof |
| CN202052007U (en) * | 2011-04-22 | 2011-11-30 | 霍红梅 | moxibustion acupuncture point sticker |
| CN102716380A (en) * | 2012-07-04 | 2012-10-10 | 甘肃省商业科技研究所 | Compound acne-removal cream and production method thereof |
| CN103333649A (en) * | 2013-06-01 | 2013-10-02 | 黄山市休宁信德成化工有限公司 | Hot-melt and pressure sensitive plaster matrigel and preparation method thereof |
| CN104352616A (en) * | 2014-10-30 | 2015-02-18 | 陈国志 | Traditional Chinese medicine composition for treating sciatica and preparation method thereof |
| CN104491304A (en) * | 2014-12-06 | 2015-04-08 | 黑龙江江恒医药科技有限公司 | Gynecological vaginal discharge prevention tablet and preparation method thereof |
| CN105030734A (en) * | 2015-08-06 | 2015-11-11 | 王永刚 | Hot-melt carrier adhesive and method for preparing emplastrum using same |
| CN105031253A (en) * | 2015-07-07 | 2015-11-11 | 柳州草子吉生物科技有限公司 | Traditional Chinese medicinal composition for treating mite dermatitis, and preparation method thereof |
| CN106038261A (en) * | 2016-05-30 | 2016-10-26 | 陈颉 | Spontaneous heating moxibustion patch |
| CN106511071A (en) * | 2016-11-23 | 2017-03-22 | 湖北鼎艾科技有限公司 | Chinese mugwort needle warming moxibustion patch |
-
2019
- 2019-01-15 CN CN201910034320.1A patent/CN109528486A/en active Pending
Patent Citations (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1611289A (en) * | 2003-10-30 | 2005-05-04 | 华中科技大学同济医学院附属同济医院 | Supercritical carbon dioxide mugwort active substance extracting method |
| CN101637189A (en) * | 2009-08-21 | 2010-02-03 | 安徽神健生物工程有限公司 | Compound traditional Chinese medicine disinfection solution and preparation method thereof |
| CN202052007U (en) * | 2011-04-22 | 2011-11-30 | 霍红梅 | moxibustion acupuncture point sticker |
| CN102716380A (en) * | 2012-07-04 | 2012-10-10 | 甘肃省商业科技研究所 | Compound acne-removal cream and production method thereof |
| CN103333649A (en) * | 2013-06-01 | 2013-10-02 | 黄山市休宁信德成化工有限公司 | Hot-melt and pressure sensitive plaster matrigel and preparation method thereof |
| CN104352616A (en) * | 2014-10-30 | 2015-02-18 | 陈国志 | Traditional Chinese medicine composition for treating sciatica and preparation method thereof |
| CN104491304A (en) * | 2014-12-06 | 2015-04-08 | 黑龙江江恒医药科技有限公司 | Gynecological vaginal discharge prevention tablet and preparation method thereof |
| CN105031253A (en) * | 2015-07-07 | 2015-11-11 | 柳州草子吉生物科技有限公司 | Traditional Chinese medicinal composition for treating mite dermatitis, and preparation method thereof |
| CN105030734A (en) * | 2015-08-06 | 2015-11-11 | 王永刚 | Hot-melt carrier adhesive and method for preparing emplastrum using same |
| CN106038261A (en) * | 2016-05-30 | 2016-10-26 | 陈颉 | Spontaneous heating moxibustion patch |
| CN106511071A (en) * | 2016-11-23 | 2017-03-22 | 湖北鼎艾科技有限公司 | Chinese mugwort needle warming moxibustion patch |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110693275A (en) * | 2019-10-23 | 2020-01-17 | 广州秋草堂健康科技有限公司 | Meridian-dredging pain-relieving neck warming pillow |
| CN111214595A (en) * | 2020-02-27 | 2020-06-02 | 郑州爱博尔医疗设备有限公司 | Production method of hot compress wax mud block |
| CN112138063A (en) * | 2020-08-05 | 2020-12-29 | 北京国人御康中医疑难病研究院(普通合伙) | Preparation method of energy moxibustion |
| CN114470145A (en) * | 2022-01-25 | 2022-05-13 | 河北化工医药职业技术学院 | Warm moxibustion type gel plaster for relieving pain of bone diseases and preparation method thereof |
| CN116712324A (en) * | 2023-04-27 | 2023-09-08 | 云南郑保制药有限公司 | Notoginseng moxibustion plaster |
| CN116712324B (en) * | 2023-04-27 | 2024-04-23 | 云南郑保制药有限公司 | Notoginseng moxibustion plaster |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN109528486A (en) | A kind of self-heating smoke-less moxibustion plaster | |
| CN109394737A (en) | Medical cold application and preparation method thereof | |
| CN105168187A (en) | Cutaneous penetration system | |
| CN104546802B (en) | Treat spontaneous heating herbal application of rheumatic arthritis and preparation method thereof | |
| CN102871790B (en) | Herbal thermal patch and production method thereof | |
| CN102166278B (en) | Chinese medicinal composition for treating pediatric rheumatoid arthritis and preparation method thereof | |
| CN105769550A (en) | Needle warming moxibustion acupoint patch containing volatile oil clathrate compound | |
| CN106924032A (en) | A kind of spontaneous heating acupoint plaster and its processing method and application | |
| CN106913603B (en) | Lucid ganoderma moxibustion patch and preparation method thereof | |
| CN101934015B (en) | Traditional Chinese medicinal composition for treating thyroid and method for preparing dispelling-goitre cataplasm thereof | |
| CN104224529A (en) | Gynecologic healthcare patch with folium artemisiae argyi | |
| CN108992240A (en) | A kind of two-sided hot moxibustion patch of breathing freely | |
| CN103041341A (en) | Traditional Chinese medicine composition for curing tuberculous exadative pleurisy and preparation method thereof | |
| KR100564659B1 (en) | Raw herbal extracts composition and cataplasa | |
| CN110201038B (en) | Wound-treating pain-relieving plaster | |
| WO2003061677A1 (en) | The healthy patch with the functions of accelerating blood circulation and expelling toxin | |
| CN1277566C (en) | Method for preparing medicine for treatment of arthralgia-syndrome pain disease | |
| CN109077924A (en) | A kind of moxa-moxibustion mud emplastrum | |
| CN105709189A (en) | Method for preparing temperature sensitive physiotherapy analgesic | |
| CN105413046A (en) | Treatment patch for acupoint application | |
| CN101904989A (en) | Chinese herbal medicament for treating pulmonary tuberculosis | |
| CN108404095A (en) | A kind of Chinese medicine transdermal patch promoting blood circulation and removing obstruction in channels for curing mammary gland hyperplasia | |
| CN201631490U (en) | Analgesic paster for thermal therapy | |
| JPH02119863A (en) | Heating moxa cautery and method thereof | |
| CN106581118A (en) | Ointment of Chinese ink made from pine soot and preparation method therefor |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20190329 |
|
| RJ01 | Rejection of invention patent application after publication |