CN107669826A - One kind treats more pathogen respiratory syndrome herbal medicines of chicken and preparation method thereof - Google Patents

One kind treats more pathogen respiratory syndrome herbal medicines of chicken and preparation method thereof Download PDF

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Publication number
CN107669826A
CN107669826A CN201710997374.9A CN201710997374A CN107669826A CN 107669826 A CN107669826 A CN 107669826A CN 201710997374 A CN201710997374 A CN 201710997374A CN 107669826 A CN107669826 A CN 107669826A
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parts
herbal medicine
chicken
pathogen
respiratory syndromes
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Inventor
滕钟秀
陈琳
邹金峰
马朝庆
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Dandong Ruifeng Animal Pharmaceutical Co Ltd
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Dandong Ruifeng Animal Pharmaceutical Co Ltd
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Priority to CN201710997374.9A priority Critical patent/CN107669826A/en
Publication of CN107669826A publication Critical patent/CN107669826A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/19Acanthaceae (Acanthus family)
    • A61K36/195Strobilanthes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/238Saposhnikovia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284Atractylodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/31Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • A61K36/315Isatis, e.g. Dyer's woad
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/34Campanulaceae (Bellflower family)
    • A61K36/346Platycodon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/489Sophora, e.g. necklacepod or mamani
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/535Perilla (beefsteak plant)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/538Schizonepeta
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/736Prunus, e.g. plum, cherry, peach, apricot or almond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/39Complex extraction schemes, e.g. fractionation or repeated extraction steps

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a kind of herbal medicine for treating the more pathogen respiratory syndromes of chicken, it is characterised in that including 10 20 parts of Radix Isatidis, 8 12 parts of perilla leaf, 8 10 parts of subprostrate sophora, 8 10 parts of blackberry lily, 8 12 parts of balloonflower root, 6 10 parts of almond, 10 15 parts of rhizoma atractylodis, 8 10 parts of schizonepeta, windproof 8 12 parts, 15 20 parts of radix glycyrrhizae, 10 20 parts of the Radix Astragali.Another object of the present invention is to the preparation method for the herbal medicine for providing the treatment more pathogen respiratory syndromes of chicken, including extract oral solution extraction process and decocting for Chinese herbal medicine technique.The herbal medicine of the treatment more pathogen respiratory syndromes of chicken prepared by the present invention, the more pathogen respiratory syndromes of control chicken of high degree, solve the problems, such as that raiser compares headache, reduce cultivation risk and economic loss, the abuse of antibiotic can be reduced simultaneously, and the chicken meat product of green, safety is exported for people.

Description

One kind treats more pathogen respiratory syndrome herbal medicines of chicken and preparation method thereof
Technical field
The present invention relates to the herbal medicine of poultry treatment, specially one kind treats the more pathogen respiratory syndrome herbal medicines of chicken And preparation method thereof.
Background technology
The more pathogen respiratory diseases of chicken are one of diseases for endangering poultry farming most serious, and pathogenic factor is more complicated, It is related to virus, mycoplasma, bacterium, immunosuppressive factor and adverse environmental factors.Main clinical manifestation is expiratory dyspnea, hello Sound, dysplasia, dissection Symptoms are that trachea-bronchial epithelial cell bleeding is serious, or even yellow cheese thing embolism, lungs occur Extravasated blood, swelling, nigrescence, huge economic loss is brought to plant.After poultry pathogen infection respiratory diseases, raiser is often It can be treated using Multiple Classes of Antibiotics, therapeutic effect is general, and it is residual to be easy to generation medicine.Herbal medicine green, no drug residue Feature has become development trend, researches and develops a kind of herbal medicine for treating the more pathogen respiratory syndromes of chicken to clinical treatment and food Product are significant safely.
The content of the invention
It is an object of the invention in view of the above-mentioned problems, overcoming prior art insufficient, there is provided one kind treats the more pathogen of chicken Herbal medicine of respiratory syndrome and preparation method thereof, reduce the loss that chicken respiratory tract disease is brought to aquaculture.
To achieve the above object, the present invention uses following technical scheme:
A kind of herbal medicine for treating the more pathogen respiratory syndromes of chicken, including Radix Isatidis 10-20 parts, perilla leaf 8-12 parts, Subprostrate sophora 8-10 parts, blackberry lily 8-10 parts, balloonflower root 8-12 parts, almond 6-10 parts, rhizoma atractylodis 10-15 parts, schizonepeta 8-10 parts, windproof 8-12 Part, radix glycyrrhizae 15-20 parts, Radix Astragali 10-20 parts.
Preferably, the herbal medicine each component and its optimization dosage are respectively:15 parts of Radix Isatidis, 10 parts of perilla leaf, subprostrate sophora 9 Part, 9 parts of blackberry lily, 10 parts of balloonflower root, 8 parts of almond, 12 parts of rhizoma atractylodis, 9 parts of schizonepeta, windproof 10 parts, 17 parts of radix glycyrrhizae, 15 parts of the Radix Astragali.
Preferably, the herbal medicine each component and its optimized amount are respectively:16 parts of Radix Isatidis, 9 parts of perilla leaf, 8 parts of subprostrate sophora, 8 parts of blackberry lily, 11 parts of balloonflower root, 9 parts of almond, 11 parts of rhizoma atractylodis, 10 parts of schizonepeta, windproof 11 parts, 19 parts of radix glycyrrhizae, 16 parts of the Radix Astragali.
Another object of the present invention is to provide the preparation method for the herbal medicine for treating the more pathogen respiratory syndromes of chicken, Comprise the following steps:The prepared slices of Chinese crude drugs are decocted using RCN heat backflow extracting concentration units, flowed back after filtering by RCN heat Extracting concentration unit concentration, place put in shady and cool storehouse it is cool after, with SG-50/250 filling liquids Cover whirling Machine, Sealingmachinewithelectromagnetismaluminumfoil Extract oral solution is made after packaging.
Preferably, the Chinese medicine is put into Chinese medicine extracting tank, adds water to cook three times, boil rear refluxing extraction 2 for the first time Hour, rear refluxing extraction is boiled for the second time 2 hours, boil rear refluxing extraction for the third time 1 hour, after being filtered, merge Decoction liquor, let cool after filtrate concentration.
Preferably, put it is cool during shady and cool storehouse environment temperature be 16-20 degrees Celsius.
Preferably, temperature is 80 degrees Celsius in the filtrate concentration process, vacuum 0.06MPa.
Beneficial effects of the present invention are:The herbal medicine of the treatment more pathogen respiratory syndromes of chicken prepared by the present invention, pole The more pathogen breathing problems of control chicken of big degree, solve the problems, such as that raiser compares headache, reduce cultivation risk and economy Loss, while the abuse of antibiotic can be reduced, the chicken meat product of green, safety is exported for people.
Embodiment
The present invention is further described below by way of specific embodiment, but the present invention is not limited only to following examples.At this In the range of invention or do not departing from present disclosure, in spirit and scope, the change that is carried out to the present invention, combining or replace Change, will be apparent to the person skilled in the art, and be included within the scope of the present invention.
A kind of herbal medicine for treating the more pathogen respiratory syndromes of chicken, including Radix Isatidis 10-20 parts, perilla leaf 8-12 parts, Subprostrate sophora 8-10 parts, blackberry lily 8-10 parts, balloonflower root 8-12 parts, almond 6-10 parts, rhizoma atractylodis 10-15 parts, schizonepeta 8-10 parts, windproof 8-12 Part, radix glycyrrhizae 15-20 parts, Radix Astragali 10-20 parts.
Embodiment 1:
Weigh 15 parts of Radix Isatidis, 10 parts of perilla leaf, 9 parts of subprostrate sophora, 9 parts of blackberry lily, 10 parts of balloonflower root, 8 parts of almond, 12 parts of rhizoma atractylodis, 9 parts of schizonepeta, windproof 10 parts, 17 parts of radix glycyrrhizae, 15 parts of the Radix Astragali, the prepared slices of Chinese crude drugs are decocted using RCN heat backflow extracting concentration units Boil, after filtering by RCN heat backflow extracting concentration unit concentration, place put in shady and cool storehouse it is cool after, SG-50/250 filling liquids rotation Extract oral solution is made after packing in lid machine, Sealingmachinewithelectromagnetismaluminumfoil.Put it is cool during the environment temperature in shady and cool storehouse be 16- 20 degrees Celsius.
In use, it is watered 300Kg-500Kg according to every 250ml decoctions.
Embodiment 2:
Weigh 15 parts of Radix Isatidis, 10 parts of perilla leaf, 9 parts of subprostrate sophora, 9 parts of blackberry lily, 10 parts of balloonflower root, 8 parts of almond, 12 parts of rhizoma atractylodis, 9 parts of schizonepeta, windproof 10 parts, 17 parts of radix glycyrrhizae, 15 parts of the Radix Astragali, the Chinese medicine is put into Chinese medicine extracting tank, added water to cook three times, the Once boil rear refluxing extraction 2 hours, boil rear refluxing extraction for the second time 2 hours, boil rear refluxing extraction for the third time 1 hour, After being filtered, merge decoction liquor, let cool after filtrate concentration.
In use, it is watered 300Kg-500Kg according to every 250ml decoctions.
Embodiment 3:
Weigh 16 parts of Radix Isatidis, 9 parts of perilla leaf, 8 parts of subprostrate sophora, 8 parts of blackberry lily, 11 parts of balloonflower root, 9 parts of almond, 11 parts of rhizoma atractylodis, chaste tree 10 parts of mustard, windproof 11 parts, 19 parts of radix glycyrrhizae, 16 parts of the Radix Astragali, the prepared slices of Chinese crude drugs are decocted using RCN heat backflow extracting concentration units Boil, after filtering by RCN heat backflow extracting concentration unit concentration, place put in shady and cool storehouse it is cool after, SG-50/250 filling liquids rotation Extract oral solution is made after packing in lid machine, Sealingmachinewithelectromagnetismaluminumfoil.Put it is cool during the environment temperature in shady and cool storehouse be 16- 20 degrees Celsius.
In use, it is watered 300Kg-500Kg according to every 250ml decoctions.
Embodiment 4:
Weigh 16 parts of Radix Isatidis, 9 parts of perilla leaf, 8 parts of subprostrate sophora, 8 parts of blackberry lily, 11 parts of balloonflower root, 9 parts of almond, 11 parts of rhizoma atractylodis, chaste tree 10 parts of mustard, windproof 11 parts, 19 parts of radix glycyrrhizae, 16 parts of the Radix Astragali, the Chinese medicine is put into Chinese medicine extracting tank, added water to cook three times, the Once boil rear refluxing extraction 2 hours, boil rear refluxing extraction for the second time 2 hours, boil rear refluxing extraction for the third time 1 hour, After being filtered, merge decoction liquor, let cool after filtrate concentration.
In use, it is watered 300Kg-500Kg according to every 250ml decoctions.
The herbal medicine of the treatment more pathogen respiratory syndromes of chicken prepared by the present invention, the more cause of diseases of control chicken of high degree Body breathing problem, solve the problems, such as that raiser compares headache, reduce cultivation risk and economic loss, while antibiosis can be reduced The abuse of element, the chicken meat product of green, safety is exported for people.
Above-described embodiment, simply presently preferred embodiments of the present invention, is not used for limiting the scope of the present invention, therefore all with this The equivalence changes that content described in invention claim is done, it all should be included within scope of the invention as claimed.

Claims (7)

1. a kind of herbal medicine for treating the more pathogen respiratory syndromes of chicken, it is characterised in that including Radix Isatidis 10-20 parts, Soviet Union Leaf 8-12 parts, subprostrate sophora 8-10 parts, blackberry lily 8-10 parts, balloonflower root 8-12 parts, almond 6-10 parts, rhizoma atractylodis 10-15 parts, schizonepeta 8-10 Part, windproof 8-12 parts, radix glycyrrhizae 15-20 parts, Radix Astragali 10-20 parts.
A kind of 2. herbal medicine for treating the more pathogen respiratory syndromes of chicken according to claim 1, it is characterised in that institute State herbal medicine each component and its optimization dosage is respectively:15 parts of Radix Isatidis, 10 parts of perilla leaf, 9 parts of subprostrate sophora, 9 parts of blackberry lily, balloonflower root 10 Part, 8 parts of almond, 12 parts of rhizoma atractylodis, 9 parts of schizonepeta, windproof 10 parts, 17 parts of radix glycyrrhizae, 15 parts of the Radix Astragali.
A kind of 3. herbal medicine for treating the more pathogen respiratory syndromes of chicken according to claim 1, it is characterised in that institute State herbal medicine each component and its optimized amount is respectively:16 parts of Radix Isatidis, 9 parts of perilla leaf, 8 parts of subprostrate sophora, 8 parts of blackberry lily, 11 parts of balloonflower root, 9 parts of almond, 11 parts of rhizoma atractylodis, 10 parts of schizonepeta, windproof 11 parts, 19 parts of radix glycyrrhizae, 16 parts of the Radix Astragali.
A kind of 4. preparation side of the herbal medicine of the treatment more pathogen respiratory syndromes of chicken described in any one of claim 1-3 Method, it is characterised in that comprise the following steps:The prepared slices of Chinese crude drugs are decocted using RCN heat backflow extracting concentration units, after filtering By RCN heat backflow extracting concentration unit concentration, place put in shady and cool storehouse it is cool after, it is mechanical, electrical with SG-50/250 filling liquid spiral covers Extract oral solution is made after magnetic aluminium foil sealing machine packaging.
5. the preparation method of the herbal medicine of the treatment more pathogen respiratory syndromes of chicken according to claim 4, its feature It is, comprises the following steps:The Chinese medicine is put into Chinese medicine extracting tank, added water to cook three times, being flowed back after boiling for the first time carries Take 2 hours, boil rear refluxing extraction for the second time 2 hours, boil rear refluxing extraction for the third time 1 hour, after being filtered, close And decoction liquor, let cool after filtrate concentration.
6. the preparation method of the herbal medicine of the treatment more pathogen respiratory syndromes of chicken according to claim 4, its feature Be, it is described put it is cool during the environment temperature in shady and cool storehouse be 16-20Shi degree.
7. the preparation method of the herbal medicine of the treatment more pathogen respiratory syndromes of chicken according to claim 5, its feature It is, temperature is 80 degrees Celsius in the filtrate concentration process, vacuum 0.06MPa.
CN201710997374.9A 2017-10-24 2017-10-24 One kind treats more pathogen respiratory syndrome herbal medicines of chicken and preparation method thereof Pending CN107669826A (en)

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Application Number Priority Date Filing Date Title
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Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101670061A (en) * 2009-08-26 2010-03-17 郑州后羿制药有限公司 Veterinary drug for treating respiratory tract infection of poultry and preparation method thereof
CN103041124A (en) * 2011-10-12 2013-04-17 董根荣 Medicament for treating avian infectious bronchitis and preparation method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101670061A (en) * 2009-08-26 2010-03-17 郑州后羿制药有限公司 Veterinary drug for treating respiratory tract infection of poultry and preparation method thereof
CN103041124A (en) * 2011-10-12 2013-04-17 董根荣 Medicament for treating avian infectious bronchitis and preparation method thereof

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