CN107648111A - A kind of Chinese herbal toothpaste - Google Patents

A kind of Chinese herbal toothpaste Download PDF

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Publication number
CN107648111A
CN107648111A CN201711029861.2A CN201711029861A CN107648111A CN 107648111 A CN107648111 A CN 107648111A CN 201711029861 A CN201711029861 A CN 201711029861A CN 107648111 A CN107648111 A CN 107648111A
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parts
chinese herbal
toothpaste
bulk drug
active component
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刘俊君
柯乙森
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/532Agastache, e.g. giant hyssop
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/534Mentha (mint)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/61Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
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  • Oral & Maxillofacial Surgery (AREA)
  • Cosmetics (AREA)
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Abstract

The invention discloses a kind of Chinese herbal toothpaste, containing the Chinese herbal medicine active component for accounting for toothpaste gross mass 0.5 ~ 20% in the toothpaste, the Chinese herbal medicine active component is prepared by the bulk drug of following weight:10 ~ 50 parts of scaly holly root, 10 ~ 50 parts of peppermint, 8 ~ 25 parts of wrinkled giant hyssop, 4 ~ 18 parts of catechu, 0.5 ~ 10 part of cloves, 3 ~ 16 parts of Oroxylum indicum.Scaly holly root in inventive formulation is clearing heat and detoxicating, is monarch drug in a prescription in side, the clearing heat and detoxicating relieving sore-throat of peppermint, wrinkled giant hyssop, catechu, Oroxylum indicum, clearing heat and detoxicating auxiliary scaly holly root is ministerial drug altogether, and cloves alleviates halitosis.Found by clinical practice, the oral problem of the symptoms such as the Chinese herbal toothpaste of the present invention is to improving with bitter taste, mouth sticks, halitosis, mouth are light, oral cavity hot gas sense, glossalgia, bleeding gums, swelling and aching of gum, dry throat, pharyngalgia is with significant effect, the property of medicine is stable, is not likely to produce dependence, can resist fungal infection, cost is low, it is convenient and practical, have no toxic side effect.

Description

A kind of Chinese herbal toothpaste
Technical field
The present invention relates to a kind of toothpaste, specifically a kind of Chinese herbal toothpaste for improving various oral problems.
Background technology
Modern Chinese oral health mainly has seven big problems, including carious tooth, dental calculus, bacterial plaque, bleeding gums, dentine Sensitivity, tooth is not pure white, implication.Oral problem has become a kind of common disease, and various awkward and pain is brought to patient, It is mainly shown as the symptoms such as dry, bitter taste, halitosis, oral cavity hot gas sense, glossalgia, bleeding gums, swelling and aching of gum, dry throat, pharyngalgia.Mouthful Chamber health can not only influence health of human body, and the symptom of many diseases is showed by oral cavity organs, so oral cavity Disease is often under cover more fearful " backstage instigator ", can never adopt a casual attitude.With lifestyle change, oral cavity is threatened to be good for The factor of health becomes more, more complicated.Interior extrinsic factor long term accumulation, joint effect oral health.
By toothwash and vitamin mainly is taken to treat for the treatment of oral problem, doctor trained in Western medicine both at home and abroad, often only Energy relief of symptoms, cures the symptoms, not the disease, and not simple and easy to do, and patient is difficult to adhere to, simultaneous gum loosens can also be certain Influence is brought to human body in degree, aggravates the appearance of oral problem, makes problem more complicatedization.Therefore western medical treatment is limited, and it is most Best method is to maintain good oral cleaning health, and toothpaste play a part of wherein as a kind of cleaning supplies it is particularly bright Aobvious, the formula of toothpaste is particularly important.
Developed with reference to the toothpaste containing Chinese medicine preparation of traditional Chinese medicine for different oral problems.Such as CN201010132459.9 discloses a kind of TCM tooth stain removing toothpaste, include in its lotion of toothpaste total composition weight ratio for 4 ~ 10% removes stain functional component, described to go the extract that stain functional component is Chinese medicine rattletop, Jehol Ligusticum Rhizome, the root of Dahurain angelica, these three traditional Chinese medicine extractions The active compound ratio of thing is rattletop:Jehol Ligusticum Rhizome:The root of Dahurain angelica=1: 1: 1;The toothpaste, which has, removes the spots such as dental exogenous mottle, protects oral cavity The effect of mucous membrane.And for example CN201210300349.8 discloses a kind of anti-inflammatory and antalgic Chinese medicinal toothpaste, in its lotion of toothpaste total composition Include the anti-inflammatory and antalgic functional component that percentage by weight is 2.3 ~ 6.9%, the anti-inflammatory and antalgic functional component extracts for ginger Thing, Radix Zanthoxyli extract and salt, these three functional component ratios are Ginger P.E:Salt:Radix Zanthoxyli extract=10:10:3; The toothpaste has anti-inflammatory and antalgic, alleviates bleeding gums, inflamed and other effects.Though in addition, conventional gargle can reach it is antibacterial, clear The effect of clean mouth chamber, but some drugses are present that the property of medicine is unstable, the deficiencies of being also easy to produce drug resistance, be invalid to fungal infection.
The content of the invention
It is an object of the invention to provide a kind of Chinese herbal toothpaste, the Chinese herbal medicine contains by scaly holly root, peppermint, wrinkled giant hyssop, catechu, Cloves, the Chinese herbal medicine active component that Oroxylum indicum is prepared, for dry, bitter taste, halitosis, oral cavity hot gas sense, glossalgia, tooth The treatment of the oral problem of the symptoms such as oulorrhagia, swelling and aching of gum, dry throat, pharyngalgia, there is the property of medicine to stablize, be not likely to produce drug resistance, The characteristics of, comfort and convenient good to fungal infection therapeutic effect can be obviously improved various oral problems.
Technical scheme is as follows:A kind of Chinese herbal toothpaste, containing accounting for toothpaste gross mass 0.5 ~ 20% in the toothpaste Chinese herbal medicine active component, the Chinese herbal medicine active component are prepared by the bulk drug of following weight:10 ~ 50 parts of scaly holly root, 10 ~ 50 parts of peppermint, 8 ~ 25 parts of wrinkled giant hyssop, 4 ~ 18 parts of catechu, 0.5 ~ 10 part of cloves, 3 ~ 16 parts of Oroxylum indicum;The Chinese herbal medicine activity into Point preparation method be:The bulk drug of above-mentioned weight is removed into impurity, section respectively, fine powder is worn into pulverizer, crosses 60 ~ 100 Mesh sieve, 80 mesh fine powders are taken, 80 mesh fine powders of obtained each bulk drug are mixed and are uniformly dispersed, sterilized, medicinal powder is made.
Preferable technical scheme is as follows:It is described containing the Chinese herbal medicine active component for accounting for toothpaste gross mass 8% in the toothpaste Chinese herbal medicine active component is prepared by the bulk drug of following weight:30 parts of scaly holly root, 30 parts of peppermint, 15 parts of wrinkled giant hyssop, catechu 10 parts, 5 parts of cloves, 10 parts of Oroxylum indicum;The preparation method of the Chinese herbal medicine active component is:The bulk drug of above-mentioned weight is distinguished Impurity, section are removed, fine powder is worn into pulverizer, crosses 80 mesh sieves, 80 mesh fine powders are taken, by 80 mesh fine powders of obtained each bulk drug Mixing is uniformly dispersed, and sterilizing, medicinal powder is made.
Preferable technical scheme is as follows:It is described containing the Chinese herbal medicine active component for accounting for toothpaste gross mass 4% in the toothpaste Chinese herbal medicine active component is prepared by the bulk drug of following weight:25 parts of scaly holly root, 40 parts of peppermint, 10 parts of wrinkled giant hyssop, catechu 4 Part, 8 parts of cloves, 16 parts of Oroxylum indicum;The preparation method of the Chinese herbal medicine active component is:The bulk drug of above-mentioned weight is removed respectively Decontamination, section, fine powder is worn into pulverizer, 60 mesh sieves is crossed, takes 60 mesh fine powders, 60 mesh fine powders of obtained each bulk drug are mixed Conjunction is uniformly dispersed, and sterilizing, medicinal powder is made.
Preferable technical scheme is as follows:Contain the Chinese herbal medicine active component for accounting for toothpaste gross mass 0.5%, institute in the toothpaste Stating Chinese herbal medicine active component is prepared by the bulk drug of following weight:10 parts of scaly holly root, 33 parts of peppermint, 8 parts of wrinkled giant hyssop, catechu 8 parts, 6 parts of cloves, 12 parts of Oroxylum indicum;The preparation method of the Chinese herbal medicine active component is:The bulk drug of above-mentioned weight is distinguished Impurity, section are removed, fine powder is worn into pulverizer, crosses 65 mesh sieves, 65 mesh fine powders are taken, by 65 mesh fine powders of obtained each bulk drug Mixing is uniformly dispersed, and sterilizing, medicinal powder is made.
Preferable technical scheme is as follows:It is described containing the Chinese herbal medicine active component for accounting for toothpaste gross mass 12% in the toothpaste Chinese herbal medicine active component is prepared by the bulk drug of following weight:20 parts of scaly holly root, 16 parts of peppermint, 12 parts of wrinkled giant hyssop, catechu 6 Part, 10 parts of cloves, 15 parts of Oroxylum indicum;The preparation method of the Chinese herbal medicine active component is:The bulk drug of above-mentioned weight is distinguished Impurity, section are removed, fine powder is worn into pulverizer, crosses 90 mesh sieves, 90 mesh fine powders are taken, by 90 mesh fine powders of obtained each bulk drug Mixing is uniformly dispersed, and sterilizing, medicinal powder is made.
Preferable technical scheme is as follows:It is described containing the Chinese herbal medicine active component for accounting for toothpaste gross mass 10% in the toothpaste Chinese herbal medicine active component is prepared by the bulk drug of following weight:50 parts of scaly holly root, 28 parts of peppermint, 25 parts of wrinkled giant hyssop, catechu 15 parts, 0.5 part of cloves, 3 parts of Oroxylum indicum;The preparation method of the Chinese herbal medicine active component is:By the bulk drug of above-mentioned weight point Not Chu Qu impurity, section, wear into fine powder with pulverizer, cross 100 mesh sieves, 100 mesh fine powders are taken, by the 100 of obtained each bulk drug The mixing of mesh fine powder is uniformly dispersed, and sterilizes, and medicinal powder is made.
Preferable technical scheme is as follows:It is described containing the Chinese herbal medicine active component for accounting for toothpaste gross mass 20% in the toothpaste Chinese herbal medicine active component is prepared by the bulk drug of following weight:40 parts of scaly holly root, 10 parts of peppermint, 14 parts of wrinkled giant hyssop, catechu 18 parts, 3.5 parts of cloves, 8 parts of Oroxylum indicum;The preparation method of the Chinese herbal medicine active component is:By the bulk drug of above-mentioned weight point Not Chu Qu impurity, section, wear into fine powder with pulverizer, cross 80 mesh sieves, take 80 mesh fine powders, 80 mesh of obtained each bulk drug are thin Powder mixing is uniformly dispersed, and sterilizes, and medicinal powder is made.
Preferable technical scheme is as follows:It is described containing the Chinese herbal medicine active component for accounting for toothpaste gross mass 15% in the toothpaste Chinese herbal medicine active component is prepared by the bulk drug of following weight:35 parts of scaly holly root, 50 parts of peppermint, 15 parts of wrinkled giant hyssop, catechu 10 parts, 2 parts of cloves, 5 parts of Oroxylum indicum;The preparation method of the Chinese herbal medicine active component is:The bulk drug of above-mentioned weight is distinguished Impurity, section are removed, fine powder is worn into pulverizer, crosses 70 mesh sieves, 70 mesh fine powders are taken, by 70 mesh fine powders of obtained each bulk drug Mixing is uniformly dispersed, and sterilizing, medicinal powder is made.
Chinese herbal toothpaste of the present invention is by Chinese herbal medicine active component medicinal powder obtained above, according to general toothpaste system Standby technique, which is added in toothpaste, to be prepared into.
The Chinese herbal medicine active component can also be by the bulk drug of following weight:30 parts of scaly holly root, 30 parts of peppermint, the leaves of pulse plants Fragrant 15 parts, 10 parts of catechu, 5 parts of cloves, 10 parts of Oroxylum indicum obtain carrying for bulk drug by hot water extraction or the mode of alcohol steep Take liquid or further concentrate extract solution and be prepared into medicinal extract, be added in toothpaste.
The extract solution of the bulk drug can be used for preparing mouthwash, the extract solution of bulk drug when for preparing mouthwash Usage ratio is:Raw material medicament extracting solution accounts for the 5 ~ 50% of mouthwash gross mass.
Effect in inventive formulation to bulk drug is as follows:
(1)Scaly holly root:It is sweet, be slightly cold, return lung, bladder warp.Heat-clearing, promote the production of body fluid, invigorate blood circulation, removing toxic substances.Cure cold, dizziness of having a headache, pyreticosis is dry Yearningly, eruptive disease, heat are rushed down, lung carbuncle, hemoptysis, laryngalgia, hemorrhoid blood, gonorrhoea, carbuncle poison, traumatic injury.
(2)Peppermint:It is pungent, cool, Return liver, lung channel.Dispelling wind and heat from the body, head clearing, relieving sore-throat promoting eruption, soothing the liver promoting the circulation of qi.Cure mainly diseases caused by external factors Wind-heat, headache, abscess of throat, food stagnation inflatable, aphtha, toothache, sore scabies, urticaria, warm disease from the beginning of, rubella itch, hypochondriac pain uncomfortable in chest.
(3)Wrinkled giant hyssop:Temperature, acrid flavour, Return liver, lung, the spleen channel.Remove dampness by means of aromatics;Anti-vomiting;Driving away summer heat inducing diaphoresis.Main damp retention in middle-jiao it Gastral cavity abdomen ruffian Min;Poor appetite;Vomiting;Diarrhea;The fever and chills headache of diseases caused by external factors summer-heat and damp;Damp-warm syndrome from the beginning of heating body be stranded;Nausea uncomfortable in chest;Nose Deep pool;Tinea of feet and hands.
(4)Catechu:It is bitter, puckery, it is slightly cold.Return lung passes through.Hygroscopic myogenic sore.For unhealing ulcer, eczema, aphtha, fall and flutter wound Bitterly, traumatism and bleeding.
(5)Cloves:It is sweet, pungent, big heat.Warm stomach, warm kidney.Control swollen stomach cold pain, hiccup, vomiting and diarrhoea, numbness pain, colic, halitosis, tooth Bitterly.Caryophyllus oil contained by it and caryophyllus oil are drunk has inhibitory action to pathogenic fungus, and its decoction is to staphylococcus, streptococcus and white The bacillus such as eye, deformation, green arteries and veins, large intestine, surplus disease, typhoid fever has inhibitory action.
(6)Oroxylum indicum:Mildly bitter flavor;It is sweet;Cold nature.Return liver, lung, stomach.Relieving sore-throat moistening lung;Soothing liver and harmonizing stomach;Expelling pus and promoting granulation.Pharynx Pain larynx numbness;Hoarseness;Cough;Stomachache due to emotional depression and the hyperactive liver-qi attacking the stomach;Sore burst for a long time and does not holds back;Acute eczema.
The occupation mode of Chinese herbal toothpaste of the present invention:Gargled with the toothpaste, 100 parts every time, 5 times a day(Three is postprandial and enter Sleep front and rear use), 5 days are 1 course for the treatment of.
Having the beneficial effect that relative to prior art of the invention:The present invention be according to traditional Chinese medical theory, it is only using Chinese medicine The special property of medicine, toothpaste technology is chosen, using scaly holly root, peppermint, wrinkled giant hyssop, catechu, cloves, Oroxylum indicum is according to certain Compatibility requirement, by being processed into.Scaly holly root in formula is clearing heat and detoxicating, for monarch drug in a prescription in side, peppermint, wrinkled giant hyssop, catechu, Oroxylum indicum Clearing heat and detoxicating relieving sore-throat, clearing heat and detoxicating auxiliary scaly holly root is ministerial drug altogether, and cloves alleviates halitosis, and stronger resist is played in we Scorching, prevention oral cavity and the effect of upper respiratory tract secondary infection.Find there is bitter taste, mouth to stick to improvement, mouth by clinical practice The oral problem of the symptoms such as smelly, mouth is light, oral cavity hot gas sense, glossalgia, bleeding gums, swelling and aching of gum, dry throat, pharyngalgia has unique Curative effect, the Chinese herbal toothpaste property of medicine of the invention is stable, is not likely to produce drug resistance, is good to fungal infection therapeutic effect, and smell is light, Fragrance is pleasant, is easy to be accepted by patients.
Embodiment
The present invention is described in further details below by embodiment, these embodiments are only used for illustrating the present invention, and Do not limit the scope of the invention.
Embodiment 1 takes the bulk drug of following weight:30 parts of scaly holly root, 30 parts of peppermint, 15 parts of wrinkled giant hyssop, 10 parts of catechu, cloves 5 parts, 10 parts of Oroxylum indicum;The bulk drug of above-mentioned weight is removed into impurity, section respectively, fine powder is worn into pulverizer, crosses 80 mesh sieves, 80 mesh fine powders are taken, 80 mesh fine powders of obtained each bulk drug are mixed and are uniformly dispersed, are sterilized, medicinal powder is made, are Chinese herbal medicine activity Composition.The said herbal medicine active component medicinal powder for accounting for toothpaste gross mass 8% is taken, toothpaste is added to according to general toothpaste making process In be prepared into the present invention Chinese herbal toothpaste.
By obtained said herbal medicine toothpaste in October, 2010 to 03 month 2011 clinical observation Gastroenterology Clinic and ward There is oral cavity disease patient 64 to be observed, clinical report is as follows:
1st, general information
All subjects are grouped into Outpatient Unit according to random digits table(20, door is carried out using Chinese herbal toothpaste of the present invention Diagnosis and treatment are treated), silver-colored even gargle group(20, using Unionpay's gargle treatment)And ward group(24, using Chinese herbal medicine tooth of the present invention Cream carries out ward treatment).
2nd, diagnostic criteria
With reference to《New Chinese medicine guideline of clinical investigations》(Zheng Xiao cornel new Chinese medicine guideline of clinical investigations》(It is tentative)It is northern Capital:China Traditional Chinese Medicine Publishing House, 2002)And《Diagnostics of Chinese Medicine》(New Century higher institutions of Chinese medicine programming textbook north Capital:China Traditional Chinese Medicine Publishing House, 2002.8)In relevant diagnostic criteria.Therefore included case need to meet following condition:Dry, Bitter taste, mouth are light, salty taste, mouth are glutinous, hot gas sense, canker sore, bleeding gums, swelling and aching of gum, dry throat, pharynx are itched, swallowed in halitosis, mouth Bitterly.
It is all to possess in above standard 1, can inclusive criteria.
3rd, treatment method
The patient is set to be using Chinese herbal toothpaste, application method made from the present embodiment:Gargled with toothpaste, 100 parts every time, daily 5 It is secondary(Three postprandial and front and rear use of falling asleep), 5 days are 1 course for the treatment of.
4th, treatment results:
4.1 with reference to《New Chinese medicine guideline of clinical investigations》(Zheng Xiao cornel new Chinese medicine guideline of clinical investigations》(Examination OK)Beijing:China Traditional Chinese Medicine Publishing House, 2002)Syndrome Scale quantifies table and formulated:All symptoms be divided into without, it is light, in, weigh 4 grades, 0,1,2,3 point is remembered respectively.
4.2 result:In 64 patients, symptom is improved after medication, wherein, Outpatient Unit is in dry, bitter taste, halitosis, mouth In a variety of disease symptoms such as the sense of chamber hot gas, glossalgia, bleeding gums, swelling and aching of gum, dry throat, pharyngalgia compared with before treatment, improve tool Statistically significant (p < 0.05);Compare between group, Outpatient Unit is in oral cavity hot gas sense, tooth with bleeding, glossalgia, tooth swelling and pain of the heel, pharynx In dry, pharyngalgia symptom, connect gargle Outpatient Unit better than ward group and silver, difference is statistically significant (p < 0.05).In the present invention Herbal medicine toothpaste is for bitter taste, mouth is glutinous, halitosis, mouth is light, it is the most obvious to improve.
5th, model case
5.1 Xu certain, man, 37 years old, main suit:Bitter taste more than 2 years.Clinical observation:Bitter taste, halitosis, constipation, red tongue body yellow and greasy fur, slippery. Using 2 courses for the treatment of of medicine of the present invention, symptom mitigation, 3 courses for the treatment of are continuing with, all symptoms disappear, and have no bitter taste halitosis.After half a year Follow-up is without recurrence.
5.2 Mr. Wangs, female, 45 years old, main suit:Bleeding gums, swelling and aching of gum, canker sore are often sent out more than half a year.Clinical observation: Halitosis, bitter taste, oral cavity hot gas sense.Using 1 course for the treatment of of medicine of the present invention, symptom mitigation is continuing with 4 courses for the treatment of, and all symptoms disappear Lose.Follow-up is without recurrence after half a year.
5.3 Lee, man, 59 years old, main suit:Halitosis more than 3 years.Clinical observation:Halitosis, oral cavity hot gas sense, bitter taste from morning.Make With 3 courses for the treatment of of medicine of the present invention, symptom mitigation is continuing with 8 courses for the treatment of, and all symptoms disappear.Follow-up is without recurrence after half a year.
Embodiment 2 takes the bulk drug of following weight:25 parts of scaly holly root, 40 parts of peppermint, 10 parts of wrinkled giant hyssop, 4 parts of catechu, cloves 8 parts, 16 parts of Oroxylum indicum;The bulk drug of above-mentioned weight is removed into impurity, section respectively, fine powder is worn into pulverizer, crosses 60 mesh sieves, 60 mesh fine powders are taken, 60 mesh fine powders of obtained each bulk drug are mixed and are uniformly dispersed, are sterilized, medicinal powder is made.Take and account for the total matter of toothpaste The said herbal medicine active component medicinal powder of amount 4%, is added in toothpaste according to general toothpaste making process and is prepared into the present invention Herbal medicine toothpaste.
Embodiment 3 takes the bulk drug of following weight:10 parts of scaly holly root, 33 parts of peppermint, 8 parts of wrinkled giant hyssop, 8 parts of catechu, cloves 6 Part, 12 parts of Oroxylum indicum;The bulk drug of above-mentioned weight is removed into impurity, section respectively, fine powder is worn into pulverizer, crosses 65 mesh sieves, 65 mesh fine powders are taken, 65 mesh fine powders of obtained each bulk drug are mixed and are uniformly dispersed, are sterilized, medicinal powder is made.Take and account for the total matter of toothpaste The said herbal medicine active component medicinal powder of amount 0.5%, it is added to according to general toothpaste making process and is prepared into the present invention's in toothpaste Chinese herbal toothpaste.
Embodiment 4 takes the bulk drug of following weight:20 parts of scaly holly root, 16 parts of peppermint, 12 parts of wrinkled giant hyssop, 6 parts of catechu, cloves 10 parts, 15 parts of Oroxylum indicum;The bulk drug of above-mentioned weight is removed into impurity, section respectively, fine powder is worn into pulverizer, crosses 90 mesh Sieve, takes 90 mesh fine powders, and 90 mesh fine powders of obtained each bulk drug are mixed and are uniformly dispersed, and sterilizes, and medicinal powder is made.Take that to account for toothpaste total The said herbal medicine active component medicinal powder of quality 12%, is added in toothpaste according to general toothpaste making process and is prepared into the present invention Chinese herbal toothpaste.
Embodiment 5 takes the bulk drug of following weight:50 parts of scaly holly root, 28 parts of peppermint, 25 parts of wrinkled giant hyssop, 15 parts of catechu, cloves 0.5 part, 3 parts of Oroxylum indicum;The bulk drug of above-mentioned weight is removed into impurity, section respectively, fine powder is worn into pulverizer, crosses 100 mesh Sieve, takes 100 mesh fine powders, and 100 mesh fine powders of obtained each bulk drug are mixed and are uniformly dispersed, and sterilizes, and medicinal powder is made.Take and account for toothpaste The said herbal medicine active component medicinal powder of gross mass 10%, it is added to according to general toothpaste making process in toothpaste and prepares cost hair Bright Chinese herbal toothpaste.
Embodiment 6 is taken by the bulk drug of following weight:40 parts of scaly holly root, 10 parts of peppermint, 14 parts of wrinkled giant hyssop, 18 parts of catechu, fourth Fragrant 3.5 parts, 8 parts of bulk drugs by above-mentioned weight of Oroxylum indicum remove impurity, section respectively, wear into fine powder with pulverizer, cross 80 mesh Sieve, takes 80 mesh fine powders, and 80 mesh fine powders of obtained each bulk drug are mixed and are uniformly dispersed, and sterilizes, and medicinal powder is made.Take the total matter of toothpaste The said herbal medicine active component medicinal powder of amount 20%, it is added to according to general toothpaste making process and is prepared into the present invention's in toothpaste Chinese herbal toothpaste.
Embodiment 7 takes the bulk drug of following weight:35 parts of scaly holly root, 50 parts of peppermint, 15 parts of wrinkled giant hyssop, 10 parts of catechu, cloves 2 parts, 5 parts of Oroxylum indicum;The bulk drug of above-mentioned weight is removed into impurity, section respectively, fine powder is worn into pulverizer, crosses 70 mesh sieves, 70 mesh fine powders are taken, 70 mesh fine powders of obtained each bulk drug are mixed and are uniformly dispersed, are sterilized, medicinal powder is made.Take and account for the total matter of toothpaste The said herbal medicine active component medicinal powder of amount 15%, it is added to according to general toothpaste making process and is prepared into the present invention's in toothpaste Chinese herbal toothpaste.

Claims (10)

  1. A kind of 1. Chinese herbal toothpaste, it is characterised in that:In toothpaste containing account for the Chinese herbal medicine activity of toothpaste gross mass 0.5 ~ 20% into Point, the Chinese herbal medicine active component is prepared by the bulk drug of following weight:10 ~ 50 parts of scaly holly root, 10 ~ 50 parts of peppermint, 8 ~ 25 parts of wrinkled giant hyssop, 4 ~ 18 parts of catechu, 0.5 ~ 10 part of cloves, 3 ~ 16 parts of Oroxylum indicum;The preparation method of the Chinese herbal medicine active component It is:The bulk drug of above-mentioned weight is removed into impurity, section respectively, fine powder is worn into pulverizer, crosses 60 ~ 100 mesh sieves, take 80 mesh thin Powder, 80 mesh fine powders of obtained each bulk drug are mixed and are uniformly dispersed, sterilized, medicinal powder is made.
  2. 2. Chinese herbal toothpaste according to claim 1, it is characterised in that:Contain in the toothpaste and account for toothpaste gross mass 8% Chinese herbal medicine active component, the Chinese herbal medicine active component are prepared by the bulk drug of following weight:30 parts of scaly holly root, peppermint 30 parts, 15 parts of wrinkled giant hyssop, 10 parts of catechu, 5 parts of cloves, 10 parts of Oroxylum indicum;The preparation method of the Chinese herbal medicine active component is:Will be upper The bulk drug for stating weight removes impurity, section respectively, wears into fine powder with pulverizer, crosses 80 mesh sieves, 80 mesh fine powders are taken, by what is obtained The 80 mesh fine powders mixing of each bulk drug is uniformly dispersed, and sterilizes, medicinal powder is made.
  3. 3. Chinese herbal toothpaste according to claim 1, it is characterised in that:Contain in the toothpaste and account for toothpaste gross mass 4% Chinese herbal medicine active component, the Chinese herbal medicine active component are prepared by the bulk drug of following weight:25 parts of scaly holly root, peppermint 40 parts, 10 parts of wrinkled giant hyssop, 4 parts of catechu, 8 parts of cloves, 16 parts of Oroxylum indicum;The preparation method of the Chinese herbal medicine active component is:Will be upper The bulk drug for stating weight removes impurity, section respectively, wears into fine powder with pulverizer, crosses 60 mesh sieves, 60 mesh fine powders are taken, by what is obtained The 60 mesh fine powders mixing of each bulk drug is uniformly dispersed, and sterilizes, medicinal powder is made.
  4. 4. Chinese herbal toothpaste according to claim 1, it is characterised in that:Contain in the toothpaste and account for toothpaste gross mass 0.5% Chinese herbal medicine active component, the Chinese herbal medicine active component is prepared by the bulk drug of following weight:It is 10 parts of scaly holly root, thin 33 parts of lotus, 8 parts of wrinkled giant hyssop, 8 parts of catechu, 6 parts of cloves, 12 parts of Oroxylum indicum;The preparation method of the Chinese herbal medicine active component is:Will be upper The bulk drug for stating weight removes impurity, section respectively, wears into fine powder with pulverizer, crosses 65 mesh sieves, 65 mesh fine powders are taken, by what is obtained The 65 mesh fine powders mixing of each bulk drug is uniformly dispersed, and sterilizes, medicinal powder is made.
  5. 5. Chinese herbal toothpaste according to claim 1, it is characterised in that:Contain in the toothpaste and account for toothpaste gross mass 12% Chinese herbal medicine active component, the Chinese herbal medicine active component is prepared by the bulk drug of following weight:It is 20 parts of scaly holly root, thin 16 parts of lotus, 12 parts of wrinkled giant hyssop, 6 parts of catechu, 10 parts of cloves, 15 parts of Oroxylum indicum;The preparation method of the Chinese herbal medicine active component is:Will The bulk drug of above-mentioned weight removes impurity, section respectively, wears into fine powder with pulverizer, crosses 90 mesh sieves, take 90 mesh fine powders, will obtain Each bulk drug 90 mesh fine powders mixing be uniformly dispersed, sterilize, be made medicinal powder.
  6. 6. Chinese herbal toothpaste according to claim 1, it is characterised in that:Contain in the toothpaste and account for toothpaste gross mass 10% Chinese herbal medicine active component, the Chinese herbal medicine active component is prepared by the bulk drug of following weight:It is 50 parts of scaly holly root, thin 28 parts of lotus, 25 parts of wrinkled giant hyssop, 15 parts of catechu, 0.5 part of cloves, 3 parts of Oroxylum indicum;The preparation method of the Chinese herbal medicine active component is: The bulk drug of above-mentioned weight is removed into impurity, section respectively, fine powder is worn into pulverizer, crosses 100 mesh sieves, take 100 mesh fine powders, will The 100 mesh fine powders mixing of obtained each bulk drug is uniformly dispersed, and sterilizes, medicinal powder is made.
  7. 7. Chinese herbal toothpaste according to claim 1, it is characterised in that:Contain in the toothpaste and account for toothpaste gross mass 20% Chinese herbal medicine active component, the Chinese herbal medicine active component is prepared by the bulk drug of following weight:It is 40 parts of scaly holly root, thin 10 parts of lotus, 14 parts of wrinkled giant hyssop, 18 parts of catechu, 3.5 parts of cloves, 8 parts of Oroxylum indicum;The preparation method of the Chinese herbal medicine active component is: The bulk drug of above-mentioned weight is removed into impurity, section respectively, fine powder is worn into pulverizer, crosses 80 mesh sieves, take 80 mesh fine powders, will To each bulk drug 80 mesh fine powders mixing be uniformly dispersed, sterilize, be made medicinal powder.
  8. 8. Chinese herbal toothpaste according to claim 1, it is characterised in that:Contain in the toothpaste and account for toothpaste gross mass 15% Chinese herbal medicine active component, the Chinese herbal medicine active component is prepared by the bulk drug of following weight:It is 35 parts of scaly holly root, thin 50 parts of lotus, 15 parts of wrinkled giant hyssop, 10 parts of catechu, 2 parts of cloves, 5 parts of Oroxylum indicum;The preparation method of the Chinese herbal medicine active component is:Will The bulk drug of above-mentioned weight removes impurity, section respectively, wears into fine powder with pulverizer, crosses 70 mesh sieves, take 70 mesh fine powders, will obtain Each bulk drug 70 mesh fine powders mixing be uniformly dispersed, sterilize, be made medicinal powder.
  9. 9. Chinese herbal toothpaste according to claim 1, it is characterised in that:The Chinese herbal medicine active component is by following weight Bulk drug:30 parts of scaly holly root, 30 parts of peppermint, 15 parts of wrinkled giant hyssop, 10 parts of catechu, 5 parts of cloves, 10 parts of Oroxylum indicum pass through hot water extraction Or the mode of alcohol steep, obtain the extract solution of bulk drug or further concentrate extract solution and be prepared into medicinal extract, be added to toothpaste In.
  10. 10. Chinese herbal toothpaste according to claim 9, it is characterised in that:The extract solution of the bulk drug is gargled for preparation Saliva, the raw material medicament extracting solution account for the 5 ~ 50% of mouthwash gross mass.
CN201711029861.2A 2017-10-30 2017-10-30 A kind of Chinese herbal toothpaste Pending CN107648111A (en)

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101083981A (en) * 2004-10-19 2007-12-05 尤尼根制药公司 Flavonoid composition for treating oral diseases

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101083981A (en) * 2004-10-19 2007-12-05 尤尼根制药公司 Flavonoid composition for treating oral diseases

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
王珍: "口洁漱对湿热证患者口腔病证及舌象光谱学表现的影响研究", 《中国博士学位论文全文数据库 医药卫生科技辑》 *

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Application publication date: 20180202