CN107596330A - A kind of Chinese medicine composition for treating swine gastric ulcer and preparation method thereof - Google Patents
A kind of Chinese medicine composition for treating swine gastric ulcer and preparation method thereof Download PDFInfo
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Abstract
The invention belongs to technical field of traditional Chinese medicines, especially a kind of Chinese medicine composition for treating swine gastric ulcer and preparation method thereof, using the membrane of a chicken's gizzard, rhizoma atractylodis, ginger, windproof, spiceleaf and the tuber of dwarf lilyturf common Six-element Chinese medicine, by reasonably arranging in pairs or groups so that the effect of collaboration is formed between medicine, and then effectively treat swine gastric ulcer, shorten treatment cycle, the present invention to technological parameter also by regulating and controlling so that the active ingredient in medicine is largely retained, and then improves drug effect；Curative effect of medication of the present invention is notable, no recurrence, edible safety, reliable, and treatment cost is low, is a kind for the treatment of preferable medicine of swine gastric ulcer.
Description
Technical field
The invention belongs to technical field of traditional Chinese medicines, especially a kind of Chinese medicine composition for treating swine gastric ulcer and its preparation side
Method.
Background technology
Swine gastric ulcer occurs and preventing and treating swine gastric ulcer is primarily referred to as stomach oesophagus work mucous membrane and angling occurs, rotten to the corn and downright bad, or
Autopepsia, form roun ulcer face, or even gastric perforation；Symptom includes apocleisis, abdominal discomfort, intestinal movement causes constipation extremely
Or diarrhoea and some case gastrorrhagias and melena etc.；This sick stomach at initial stage is in slight bleeding, only shows indigestion, people are often
It is not easy to discover., can be dead rapidly during the acute more chronic peritonitis that occurs together after gastric perforation；Often in distributing, cause in a group pig
Indivedual pigs are dead；This disease can betide any age, but be more common in more than 50kg and grow rapid pig and raise spacing in monomer
Sow in column；There is morbidity throughout the year, but it is more common with the summer and autumn of sweltering heat.
The problem of using western medicine swine gastric ulcer side effect larger in the prior art, and easily causing medicament residue, and
And western medicine has the effect of obvious to single illness or a kind of illness, for the more disease of illness, curative effect is simultaneously failed to understand
It is aobvious in turn result in costly, it is necessary to coordinate other Western medicine to be treated, and use treatment by Chinese herbs, treatment cycle length, and treatment
Effect is undesirable；As disclosed in patent CN201310672298.6 it is a kind of using the root of straight ladybell, dried mushroom, the stem of noble dendrobium, knife ash tree, honeysuckle,
Dried orange peel, cloves, the tuber of dwarf lilyturf, sweet potato, Chinese coffeetree fruit, scarlet kadsura root, deliver vegetables, Chinese herbaceous peony, honeycomb, garlic, the membrane of a chicken's gizzard, Plant Soot, rice sprout and big
Jujube is the medicine for the treatment swine gastric ulcer that raw material is prepared into, and medicament categories are various.
The content of the invention
In order to solve the above technical problems, the present invention provides a kind of Chinese medicine composition for treating swine gastric ulcer and its preparation side
Method.
It is achieved particular by following technical scheme：
A kind of Chinese medicine composition for treating swine gastric ulcer, include the raw material of following parts by weight：10~20 parts of the membrane of a chicken's gizzard, rhizoma atractylodis
10~20 parts, 20~30 parts of ginger, windproof 12~17 parts, 3~7 parts of spiceleaf, 4~8 parts of the tuber of dwarf lilyturf.
The raw material is in parts by weight：17 parts of the membrane of a chicken's gizzard, 16 parts of rhizoma atractylodis, 28 parts of ginger, windproof 15 parts, 5 parts of spiceleaf, wheat
7 parts of winter.
Also include 5~10 parts of paper mulberry bark in the raw material.
The raw material also includes medically acceptable auxiliary material.
The preparation method of the Chinese medicine composition of above-mentioned treatment swine gastric ulcer, comprises the following steps：
(1) the membrane of a chicken's gizzard, rhizoma atractylodis, ginger and spiceleaf are measured according to formula, are shredded after mixing, put into mixer in stirring 30~
40min, adds 4~6 times of water of its mixed weight, decocts 2~3h, after filtering, filter residue add 2~4 times of decoctings of its weight boil 1~
2h, filtering, filtrate will be merged twice, and relative density is 1.26~1.31 thick paste when being concentrated into 60~70 DEG C, then through spray
Mist drying crosses 100 mesh sieves, obtains medicinal powder A to powder；
(2) measured according to formula it is windproof, after being crushed to 100~200 mesh, using water as solvent, ultrasonic extraction 4~5 times；According to
After formula measures the tuber of dwarf lilyturf, is crushed to 100~200 mesh, using 70~80% ethanol as solvent, ultrasonic extraction 2~3 times；By windproof and
Radix Ophiopogonis extract merges, filtration, filtrate recycling ethanol, and relative density is 1.32~13.37 when being concentrated into 60~70 DEG C
Thick paste, then it is spray-dried to powder, 100 mesh sieves are crossed, obtain medicinal powder B；
(3) medicinal powder A and medicinal powder B are merged, stirred.
The windproof ultrasonic extraction temperature is 27.5~31.5 DEG C, and extraction time be 20~30min, extraction frequency for 30~
40KHz。
The tuber of dwarf lilyturf ultrasonic extraction temperature is 35~40 DEG C, and extraction time be 40~60min, extraction frequency for 30~
40KHz。
Beneficial effect
The present invention uses the membrane of a chicken's gizzard, rhizoma atractylodis, ginger, windproof, spiceleaf and the tuber of dwarf lilyturf common Six-element Chinese medicine, by reasonably arranging in pairs or groups,
So that the effect of collaboration is formed between medicine, and then swine gastric ulcer is effectively treated, shorten treatment cycle, the present invention is also by right
Technological parameter is regulated and controled so that the active ingredient in medicine is largely retained, and then improves drug effect；Medicine of the present invention
Thing is evident in efficacy, no recurrence, edible safety, reliable, and treatment cost is low, is a kind for the treatment of preferable medicine of swine gastric ulcer.
Therapeutic effect is verified：
Test method：Experiment is 70~75kg from the pig totally 135 with swine gastric ulcer, body weight, sick pig clinic table
It is now poor appetite, One's spirits are drooping, void excreta has diarrhea and vomiting, weight loss for dark brown, idol；Sick pig is randomly divided into
2 groups, test group 68, control group 67；Wherein test group sick pig adds medicine of the present invention in its feed, and addition is according to feeding
The 1~2% of material weight is added, and control group sick pig adds the medicine of patent CN201310672298.6 preparations in its feed
Thing, addition are added according to the 3~8% of feed relative, and the test period is 3~5d：
Criterion of therapeutical effect：The treatment time limit is up to 3d, appetite, spirit and defecation etc. and recovered normally, and symptoms of emesis, which disappears, to be regarded
To be effective；Treatment phase is limited to 4~5d, and appetite has taken a turn for the better, mental restoration is normal, and excrement is normal, no vomiting phenomenon；It is invalid：Food
It is intended to the depressed, state of mind not improve, appointing has vomiting phenomenon；Two groups of drug therapy results such as table 1：
The therapeutic effect of table 1 contrasts
| Group | It is effective | Obvious effective rate % | Effectively | Efficient % | It is invalid | Inefficiency % | Total effective rate % |
| Test group | 58 | 85.3 | 9 | 13.2 | 1 | 1.5 | 98.5 |
| Control group | 45 | 67.2 | 16 | 23.9 | 6 | 8.9 | 91.5 |
As seen from the experiment, test group obvious effective rate is significantly higher than control group, and test group effective percentage is less than control group, tested
Group inefficiency is less than control group, and test group total effective rate has reached 98.5%, is higher by control group 7%；Therefore, using medicine of the present invention
Thing has the advantages for the treatment of cycle is short, and therapeutic effect is notable to treating swine gastric ulcer.
Embodiment
Tuberculosis specific embodiment is limited technical scheme is further below, but claimed
Scope is not only limited to made description.
Embodiment 1
A kind of Chinese medicine composition for treating swine gastric ulcer, include the raw material of following parts by weight：The membrane of a chicken's gizzard 1kg, rhizoma atractylodis 1kg,
Ginger 2kg, windproof 1.2kg, spiceleaf 0.3kg, tuber of dwarf lilyturf 0.4kg.
The preparation method of the Chinese medicine composition of above-mentioned treatment swine gastric ulcer, comprises the following steps：
(1) the membrane of a chicken's gizzard, rhizoma atractylodis, ginger and spiceleaf are measured according to formula, is shredded after mixing, put into mixer and stir
30min, 4 times of water of its mixed weight are added, decoct 2h, after filtering, filter residue adds the 2 times of decoctings of its weight and boils 1h, filtering, will twice
Filtrate merges, and relative density is 1.26 thick paste when being concentrated into 60 DEG C, then spray-dried to powder, crosses 100 mesh sieves, obtains
Medicinal powder A；
(2) measured according to formula it is windproof, after being crushed to 100 mesh, using water as solvent, ultrasonic extraction 4 times；Measured according to formula
The tuber of dwarf lilyturf, after being crushed to 100 mesh, using 70% ethanol as solvent, ultrasonic extraction 2 times；Windproof and Radix Ophiopogonis extract is merged, filtered
Cross, filtrate recycling ethanol, relative density is 1.32 thick paste when being concentrated into 60 DEG C, then spray-dried to powder, crosses 100 mesh
Sieve, obtains medicinal powder B；
(3) medicinal powder A and medicinal powder B are merged, stirred.
The windproof ultrasonic extraction temperature is 27.5 DEG C, extraction time 20min, and extraction frequency is 30KHz.
The tuber of dwarf lilyturf ultrasonic extraction temperature is 35 DEG C, extraction time 40min, and extraction frequency is 30KHz.
Embodiment 2
A kind of Chinese medicine composition for treating swine gastric ulcer, include the raw material of following parts by weight：The membrane of a chicken's gizzard 2kg, rhizoma atractylodis 2kg,
Ginger 3kg, windproof 1.7kg, spiceleaf 0.7kg, tuber of dwarf lilyturf 0.8kg.
The preparation method of the Chinese medicine composition of above-mentioned treatment swine gastric ulcer, comprises the following steps：
(1) the membrane of a chicken's gizzard, rhizoma atractylodis, ginger and spiceleaf are measured according to formula, is shredded after mixing, put into mixer and stir
40min, 6 times of water of its mixed weight are added, decoct 3h, after filtering, filter residue adds the 4 times of decoctings of its weight and boils 2h, filtering, will twice
Filtrate merges, and relative density is 1.31 thick paste when being concentrated into 70 DEG C, then spray-dried to powder, crosses 100 mesh sieves, obtains
Medicinal powder A；
(2) measured according to formula it is windproof, after being crushed to 200 mesh, using water as solvent, ultrasonic extraction 5 times；Measured according to formula
The tuber of dwarf lilyturf, after being crushed to 200 mesh, using 80% ethanol as solvent, ultrasonic extraction 3 times；Windproof and Radix Ophiopogonis extract is merged, filtered
Cross, filtrate recycling ethanol, relative density is 13.37 thick paste when being concentrated into 70 DEG C, then spray-dried to powder, crosses 100 mesh
Sieve, obtains medicinal powder B；
(3) medicinal powder A and medicinal powder B are merged, stirred.
The windproof ultrasonic extraction temperature is 31.5 DEG C, extraction time 30min, and extraction frequency is 40KHz.
The tuber of dwarf lilyturf ultrasonic extraction temperature is 40 DEG C, extraction time 60min, and extraction frequency is 40KHz.
Embodiment 3
A kind of Chinese medicine composition for treating swine gastric ulcer, include the raw material of following parts by weight：The raw material is in parts by weight
For：The membrane of a chicken's gizzard 1.7kg, rhizoma atractylodis 1.6kg, ginger 2.8kg, windproof 1.5kg, spiceleaf 0.5kg, tuber of dwarf lilyturf 0.7kg.
The preparation method of the Chinese medicine composition of above-mentioned treatment swine gastric ulcer, comprises the following steps：
(1) the membrane of a chicken's gizzard, rhizoma atractylodis, ginger and spiceleaf are measured according to formula, is shredded after mixing, put into mixer and stir
35min, 5 times of water of its mixed weight are added, decoct 2.5h, after filtering, filter residue adds the 3 times of decoctings of its weight and boils 1.5h, filters, will
Filtrate merges twice, and relative density is 1.28 thick paste when being concentrated into 65 DEG C, then spray-dried to powder, crosses 100 mesh
Sieve, obtains medicinal powder A；
(2) measured according to formula it is windproof, after being crushed to 140 mesh, using water as solvent, ultrasonic extraction 5 times；Measured according to formula
The tuber of dwarf lilyturf, after being crushed to 180 mesh, using 75% ethanol as solvent, ultrasonic extraction 3 times；Windproof and Radix Ophiopogonis extract is merged, filtered
Cross, filtrate recycling ethanol, relative density is 1.35 thick paste when being concentrated into 68 DEG C, then spray-dried to powder, crosses 100 mesh
Sieve, obtains medicinal powder B；
(3) medicinal powder A and medicinal powder B are merged, stirred.
The windproof ultrasonic extraction temperature is 30 DEG C, extraction time 25min, and extraction frequency is 35KHz.
The tuber of dwarf lilyturf ultrasonic extraction temperature is 38 DEG C, extraction time 50min, and extraction frequency is 40KHz.
Test example 1
Test group medicine：The medicine prepared using the scheme of embodiment 1；
Control group medicine：The medicine prepared using the scheme of embodiment 1,0.3~0.5kg mulberry tree is added with its medicine
Skin；
60 pigs are selected in experiment, and body weight in 65~70kg, is randomly divided into two groups, every group 30, two groups respectively according to feeding
Material weight 1~3% is added, and by 30d test period, to two groups of experiment pig venous blood collections, blood sampling time is that early morning is empty
Before abdomen, and using the content of IgA, IgG, IgM in full automatic biochemical apparatus measure serum, as a result such as table 2 below；
Table 2
As seen from the experiment, IgA, IgG and IgM content are below control group in the serum of test group pig, it can be seen that,
In embodiment 1 in medicine composition, addition paper mulberry bark can significantly improve the immunocompetence of pig.
It is important to point out that, above example and test example are only limitted to do further technical scheme herein
Elaboration and understanding, it is impossible to be interpreted as further to technical scheme and limited, what those skilled in the art made
Non-protruding essential characteristics and the innovation and creation of marked improvement, still fall within the protection category of the present invention.
Claims (7)
1. a kind of Chinese medicine composition for treating swine gastric ulcer, it is characterised in that include the raw material of following parts by weight：The membrane of a chicken's gizzard 10~
20 parts, 10~20 parts of rhizoma atractylodis, 20~30 parts of ginger, windproof 12~17 parts, 3~7 parts of spiceleaf, 4~8 parts of the tuber of dwarf lilyturf.
2. the Chinese medicine composition for the treatment of swine gastric ulcer as claimed in claim 1, it is characterised in that the raw material is in parts by weight
For：17 parts of the membrane of a chicken's gizzard, 16 parts of rhizoma atractylodis, 28 parts of ginger, windproof 15 parts, 5 parts of spiceleaf, 7 parts of the tuber of dwarf lilyturf.
3. the Chinese medicine composition for the treatment of swine gastric ulcer as claimed in claim 1 or 2, it is characterised in that also include in the raw material
There is 3~5 parts of paper mulberry bark.
4. the Chinese medicine composition for the treatment of swine gastric ulcer as claimed in claim 1 or 2, it is characterised in that the raw material also includes doctor
Acceptable auxiliary material on.
5. as claimed in claim 1 or 2 treatment swine gastric ulcer Chinese medicine composition preparation method, it is characterised in that including with
Lower step：
(1) the membrane of a chicken's gizzard, rhizoma atractylodis, ginger and spiceleaf are measured according to formula, are shredded after mixing, put into mixer in stirring 30~
40min, adds 4~6 times of water of its mixed weight, decocts 2~3h, after filtering, filter residue add 2~4 times of decoctings of its weight boil 1~
2h, filtering, filtrate will be merged twice, and relative density is 1.26~1.31 thick paste when being concentrated into 60~70 DEG C, then through spray
Mist drying crosses 100 mesh sieves, obtains medicinal powder A to powder；
(2) measured according to formula it is windproof, after being crushed to 100~200 mesh, using water as solvent, ultrasonic extraction 4~5 times；According to formula
After measuring the tuber of dwarf lilyturf, being crushed to 100~200 mesh, using 70~80% ethanol as solvent, ultrasonic extraction 2~3 times；By the windproof and tuber of dwarf lilyturf
Extract solution merges, filtration, filtrate recycling ethanol, and relative density is 1.32~13.37 thick paste when being concentrated into 60~70 DEG C,
It is spray-dried to powder again, 100 mesh sieves are crossed, obtain medicinal powder B；
(3) medicinal powder A and medicinal powder B are merged, stirred.
6. the preparation method of the Chinese medicine composition for the treatment of swine gastric ulcer as claimed in claim 5, it is characterised in that described windproof super
Sound Extracting temperature is 27.5~31.5 DEG C, and extraction time is 20~30min, and extraction frequency is 30~40KHz.
7. the preparation method of the Chinese medicine composition for the treatment of swine gastric ulcer as claimed in claim 5, it is characterised in that the tuber of dwarf lilyturf surpasses
Sound Extracting temperature is 35~40 DEG C, and extraction time is 40~60min, and extraction frequency is 30~40KHz.
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103610991A (en) * | 2013-12-12 | 2014-03-05 | 山东新希望六和集团有限公司 | Medicine for treating swine gastric ulcer and preparation method thereof |
| CN104667145A (en) * | 2013-11-26 | 2015-06-03 | 天津瑞贝特科技发展有限公司 | Traditional Chinese medicine composition for treating swine gastric ulcer and preparation method thereof |
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2017
- 2017-10-29 CN CN201711039542.XA patent/CN107596330A/en active Pending
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104667145A (en) * | 2013-11-26 | 2015-06-03 | 天津瑞贝特科技发展有限公司 | Traditional Chinese medicine composition for treating swine gastric ulcer and preparation method thereof |
| CN103610991A (en) * | 2013-12-12 | 2014-03-05 | 山东新希望六和集团有限公司 | Medicine for treating swine gastric ulcer and preparation method thereof |
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Application publication date: 20180119 |
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