CN106692857A

CN106692857A - Traditional Chinese medicine composition for treating babesiasis

Info

Publication number: CN106692857A
Application number: CN201611136765.3A
Authority: CN
Inventors: 张俊清; 张明
Original assignee: Individual
Current assignee: Individual
Priority date: 2016-12-12
Filing date: 2016-12-12
Publication date: 2017-05-24

Abstract

The invention discloses a traditional Chinese medicine composition for treating babesiasis and belongs to the technical field of traditional Chinese veterinary medicines. The traditional Chinese medicine composition provided by the invention is prepared from the following components in parts by weight: 40 to 65 parts of sophora flavescens, 40 to 60 parts of herba artemisiae annuae, 40 to 60 parts of artemisia dubia, 40 to 60 parts of radix rubiae, 30 to 50 parts of pteris semipinnata, 40 to 60 parts of root of chinese barberry, 10 to 30 parts of ginger baked rhizoma coptidis, 40 to 60 parts of slender dutchmanspipe root, 20 to 40 parts of fructus amomi rotundus, 5 to 20 parts of saffron, 25 to 45 parts of salt stir-fried fructus tsaoko, 90 to 110 parts of conic gymnadenia tuber, 20 to 40 parts of saxifraga stolonifera, 40 to 60 parts of honey baked radix adenophorae and 15 to 30 parts of honey baked liquorice root. The main medicines of the composition contain sophocarpidine and artesunate which have the effects of resisting trichomonad and amebic protozoa, so the traditional Chinese medicine composition has strong effects of inhibiting and killing malaria parasite and babesia, has exact curative effect and does not have any toxic or side effects in clinical application.

Description

A kind of Chinese medicine composition for treating the western babesiasis of horse BABEI

Technical field

The invention belongs to technical field of Chinese veterinary medicine, in particular, belong to a kind of Chinese medicine for treating the western babesiasis of horse BABEI Composition.

Background technology

Horse Jiao worm is also referred to as horse and receives decoking parasitosis in the prior art, and its pathogen is that horse BABEI west Jiao worm is small-sized polypide, worm Radius of the body length no more than red blood cell.Form of diverse, there is circular, oval, single pyriform, spindle, nail-shaped, comma shape.

The western babesiasis of horse BABEI because：The tick class for propagating horse BABEI west Jiao worm is a lot, wherein leather tick is major transmitter, health Horse is subject to leather tick to bite and be infected this disease.

The primary symptom of the western babesiasis of horse BABEI：Sick horse initial stage body temperature is raised, in intermittent fever or indefinite form heat, spiritual depressed, food Be intended to go down, conjunctiva xanthochromia, anaemia of gradually becoming thin, limbs bottom oedema.This disease can cause large quantities of dead, pregnant horses in neopathy area Miscarriage is very high to young coltfoal harm Serious Mortality rate.

The diagnosis of the western babesiasis of horse BABEI：Blood smear is made in the blood sampling of sick horse have sharp ears, is shown in height with Ji's nurse Sa decoration method BABEI west Jiao worm polypide is detected under micro mirror can make a definite diagnosis.

Prior art treats the western babesiasis of horse BABEI, and mostly based on flavacridin hydrochloride, Benny's that, above medicine needs to repeat to make With, drug residue is high, and the liver, kidney and other organs to domestic animal stimulate infringement big, is also easy to produce drug resistance and drug accumulation poisoning, Therapeutic effect has much room for improvement.

The content of the invention

The present invention gives a kind of Chinese medicine group for treating the western babesiasis of horse BABEI to efficiently solve above technical problem Compound.

A kind of Chinese medicine composition for treating the western babesiasis of horse BABEI of the invention, it is characterised in that by following weight portion group Into：Kuh-seng 40-65 parts, sweet wormwood 40-60 parts, subdigitate wormwood herb 40-60 parts, madder 40-60 parts, Semi-pinnated Brake Herb 30-50 parts, barberry 40- 60 parts, ginger process coptis 10-30 parts, dutchmanspipe root 40-60 parts, Amomum cardamomum 20-40 parts, safflower 5-20 parts, salt stir-baked FRUCTUS TSAOKO 25-45 Part, conic gymnadenia tuber 90-110 parts, 20-40 parts of umbrella handle kiss-me, honey process the root of straight ladybell 40-60 parts, Radix Glycyrrhizae (processed with honey) 15-30 parts.

The Chinese medicine composition of the treatment western babesiasis of horse BABEI in accordance with the above, it is preferable that constituted by following weight portion：It is bitter 40 parts of ginseng, 40 parts of sweet wormwood, 40 parts of subdigitate wormwood herb, 40 parts of madder, 30 parts of Semi-pinnated Brake Herb, 40 parts of barberry, ginger process 10 parts of the coptis, dutchmanspipe root 40 parts, 20 parts of Amomum cardamomum, 5 parts of safflower, 25 parts of salt stir-baked FRUCTUS TSAOKO, 90 parts of conic gymnadenia tuber, 20 parts of umbrella handle kiss-me, honey process the root of straight ladybell 40 Part, 15 parts of Radix Glycyrrhizae (processed with honey).

The Chinese medicine composition of the treatment western babesiasis of horse BABEI in accordance with the above, it is preferable that constituted by following weight portion：It is bitter 65 parts of ginseng, 60 parts of sweet wormwood, 60 parts of subdigitate wormwood herb, 60 parts of madder, 50 parts of Semi-pinnated Brake Herb, 60 parts of barberry, ginger process 30 parts of the coptis, dutchmanspipe root 60 parts, 40 parts of Amomum cardamomum, 20 parts of safflower, 45 parts of salt stir-baked FRUCTUS TSAOKO, 110 parts of conic gymnadenia tuber, 40 parts of umbrella handle kiss-me, honey process the root of straight ladybell 60 Part, 30 parts of Radix Glycyrrhizae (processed with honey).

The Chinese medicine composition of the treatment western babesiasis of horse BABEI in accordance with the above, it is preferable that constituted by following weight portion：It is bitter 43 parts of ginseng, 42 parts of sweet wormwood, 43 parts of subdigitate wormwood herb, 44 parts of madder, 32 parts of Semi-pinnated Brake Herb, 43 parts of barberry, ginger process 12 parts of the coptis, dutchmanspipe root 43 parts, 22 parts of Amomum cardamomum, 7 parts of safflower, 28 parts of salt stir-baked FRUCTUS TSAOKO, 93 parts of conic gymnadenia tuber, 23 parts of umbrella handle kiss-me, honey process the root of straight ladybell 42 Part, 17 parts of Radix Glycyrrhizae (processed with honey).

The Chinese medicine composition of the treatment western babesiasis of horse BABEI in accordance with the above, it is preferable that constituted by following weight portion：It is bitter 45 parts of ginseng, 44 parts of sweet wormwood, 46 parts of subdigitate wormwood herb, 47 parts of madder, 35 parts of Semi-pinnated Brake Herb, 45 parts of barberry, ginger process 15 parts of the coptis, dutchmanspipe root 46 parts, 24 parts of Amomum cardamomum, 9 parts of safflower, 30 parts of salt stir-baked FRUCTUS TSAOKO, 96 parts of conic gymnadenia tuber, 25 parts of umbrella handle kiss-me, honey process the root of straight ladybell 45 Part, 19 parts of Radix Glycyrrhizae (processed with honey).

The Chinese medicine composition of the treatment western babesiasis of horse BABEI in accordance with the above, it is preferable that constituted by following weight portion：It is bitter 49 parts of ginseng, 48 parts of sweet wormwood, 49 parts of subdigitate wormwood herb, 48 parts of madder, 37 parts of Semi-pinnated Brake Herb, 48 parts of barberry, ginger process 18 parts of the coptis, dutchmanspipe root 49 parts, 27 parts of Amomum cardamomum, 11 parts of safflower, 33 parts of salt stir-baked FRUCTUS TSAOKO, 98 parts of conic gymnadenia tuber, 29 parts of umbrella handle kiss-me, honey process the root of straight ladybell 48 Part, 22 parts of Radix Glycyrrhizae (processed with honey).

The Chinese medicine composition of the treatment western babesiasis of horse BABEI in accordance with the above, it is preferable that constituted by following weight portion：It is bitter 52 parts of ginseng, 50 parts of sweet wormwood, 51 parts of subdigitate wormwood herb, 50 parts of madder, 40 parts of Semi-pinnated Brake Herb, 50 parts of barberry, ginger process 21 parts of the coptis, dutchmanspipe root 52 parts, 29 parts of Amomum cardamomum, 13 parts of safflower, 38 parts of salt stir-baked FRUCTUS TSAOKO, 100 parts of conic gymnadenia tuber, 32 parts of umbrella handle kiss-me, honey process the root of straight ladybell 50 Part, 24 parts of Radix Glycyrrhizae (processed with honey).

The Chinese medicine composition of the treatment western babesiasis of horse BABEI in accordance with the above, it is preferable that constituted by following weight portion：It is bitter 54 parts of ginseng, 52 parts of sweet wormwood, 53 parts of subdigitate wormwood herb, 52 parts of madder, 42 parts of Semi-pinnated Brake Herb, 53 parts of barberry, ginger process 23 parts of the coptis, dutchmanspipe root 54 parts, 31 parts of Amomum cardamomum, 15 parts of safflower, 42 parts of salt stir-baked FRUCTUS TSAOKO, 102 parts of conic gymnadenia tuber, 34 parts of umbrella handle kiss-me, honey process the root of straight ladybell 52 Part, 26 parts of Radix Glycyrrhizae (processed with honey).

The Chinese medicine composition of the treatment western babesiasis of horse BABEI in accordance with the above, it is preferable that constituted by following weight portion：It is bitter 56 parts of ginseng, 54 parts of sweet wormwood, 55 parts of subdigitate wormwood herb, 54 parts of madder, 45 parts of Semi-pinnated Brake Herb, 56 parts of barberry, ginger process 26 parts of the coptis, dutchmanspipe root 56 parts, 35 parts of Amomum cardamomum, 17 parts of safflower, 43 parts of salt stir-baked FRUCTUS TSAOKO, 105 parts of conic gymnadenia tuber, 36 parts of umbrella handle kiss-me, honey process the root of straight ladybell 54 Part, 28 parts of Radix Glycyrrhizae (processed with honey).

The Chinese medicine composition of the treatment western babesiasis of horse BABEI in accordance with the above, it is preferable that constituted by following weight portion：It is bitter 58 parts of ginseng, 56 parts of sweet wormwood, 57 parts of subdigitate wormwood herb, 58 parts of madder, 48 parts of Semi-pinnated Brake Herb, 58 parts of barberry, ginger process 28 parts of the coptis, dutchmanspipe root 58 parts, 38 parts of Amomum cardamomum, 19 parts of safflower, 44 parts of salt stir-baked FRUCTUS TSAOKO, 108 parts of conic gymnadenia tuber, 38 parts of umbrella handle kiss-me, honey process the root of straight ladybell 56 Part, 24 parts of Radix Glycyrrhizae (processed with honey).

Property of medicine effect of each component in the treatment western babesiasis Chinese medicine composition of horse BABEI of the invention：

Kuh-seng：Nature and flavor：It is bitter, cold.Return through：Return liver, large and small intestines warp.Effect：Heat-clearing and damp-drying drug, wind dispelling insecticide.Cure mainly：Have anti- Shang worms, Amoeba effect, jaundice with damp-heat pathogen, intestines Huang rush down, hot dysentery is had blood in stool.

Sweet wormwood：Nature and flavor：It is bitter, cold.Return through：Return liver, gallbladder channel.Effect：Removing summer-heat, reducing the asthenic fever.Cure mainly：To cruel protozoon, Jiao Worm, have very high inhibition act on.Acute and chronic enteritis, stomach and intestine fire are contained, long heat is not moved back.

Subdigitate wormwood herb：Nature and flavor：It is hardship, micro-pungent, cool in nature.Return through：Return liver, lung channel.Effect：Clearing heat and cooling blood, removing toxic substances desinsection.Cure mainly： Acute fever, abscess of throat, universal eczema.

Madder：It is bitter, cool in nature.Return through：Return liver warp.Effect：Removing heat from blood, only diarrhoea.Cure mainly：Blood-head, diarrhoea, haematemesis, fiber crops Rash.

Semi-pinnated Brake Herb：Nature and flavor：It is sweet, sour, pungent, warm in nature.Effect：Clearing heat and detoxicating, scattered silt, detumescence, analgesic.Cure mainly：Bloody flux, intestines are yellow Rush down.

Radix berberidis：Nature and flavor：It is bitter, cold.Effect：Qinghua is damp and hot, purging intense heat and detonicating, promoting blood circulation scattered silt.Cure mainly：Damp-heat dysentery, intestines are yellow, Jaundice with damp-heat pathogen.

Ginger processs the coptis：Nature and flavor：It is bitter, cold.Return through：The thoughts of returning home, spleen, liver, large intestine channel.Effect：Heat-clearing and damp-drying drug, purging intense heat and detonicating.It is main Control：Sore and toxic, jaundice with damp-heat pathogen, Chang Yellow rush down dysenteries.Ginger processs that can to lower medicine cold.

Dutchmanspipe root：Nature and flavor：Acrid, bitter, warm.Return through：Return liver, lung, the spleen channel.Effect：Promoting qi circulation and relieving pain, stimulating appetite.Cure mainly：Tripe Distention and fullness in the abdomen, heating, cough with lung heat, jaundice.

Amomum cardamomum：Nature and flavor：Pungent, temperature.Return through：Return lung, spleen, stomach.Effect：Dampness elimination is amusing, warm stomach preventing or arresting vomiting.Cure mainly：Loss of appetite is received Less, yellowish fur.

Safflower：Nature and flavor：Warm, sweet, slight bitter.Return through；The thoughts of returning home, Liver Channel.Effect：Blood-nourishing, invigorate blood circulation, enrich blood, promoting circulation of blood, regulating blood condition, Dissolving stasis, dredging collateral.Cure mainly；Anemia is physically weak.Shape has obvious improvement.Safflower amount is small to enrich blood, measures and play promoting blood circulation effect greatly.

Salt stir-baked FRUCTUS TSAOKO：Nature and flavor：Pungent, temperature.Return through：Return liver, stomach.Effect：Warming middle-JIAO and strengthening the spleen, strengthening the spleen and stomach.Cure mainly：Taste are not Tripe distention and fullness in the abdomen, anorexia caused by fortune.Salt stir-baked FRUCTUS TSAOKO strengthens nourishing Yin and falling fire function.

Conic gymnadenia tuber：Nature and flavor：It is sweet, flat, puckery, warm in nature.Return through：Return stomach, lung, the spleen channel.Effect：Yishen Jianpi, tonifying Qi and blood, it is raw Quench the thirst in Tianjin.Cure mainly：Carcass is thin and weak, consumptive disease is become thin.

Umbrella handle kiss-me：Nature and flavor：It is sweet, cool.Return through：Returns spleen, lung channel.Effect：Clearing heat and detoxicating, sharp liver and gall.Cure mainly：Sternal rib aches Bitterly, anemopyretic cold.

Honey processs the root of straight ladybell：Nature and flavor：It is sweet, cool.Return through：Attach to the lung and stomach meridians.Effect：Moisten the lung and relieve the cough, nourishing Yin and promoting production of body fluid.Cure mainly：After pyreticosis The mouth of phase Yin and fluid deficiency is dry, thirsty to wait disease.Honey is processed the root of straight ladybell and strengthens tonifying middle-Jiao and Qi function.

Radix Glycyrrhizae (processed with honey)：Nature and flavor：It is flat, sweet.Return through：Return 12 warps.Effect：Tonifying Qi and in, relax the property of medicine, emergency analgesic therapy, solution The work(of poison.Cure mainly：Weakness of the spleen and the stomach, expelling phlegm and arresting coughing.Radix Glycyrrhizae (processed with honey) enhancing moistens the lung and relieve the cough, tonifying middle-Jiao and Qi effect, each medicine in mitigation side The property of medicine, lowers toxic and side effect.

The principle of reatment of the Chinese medicine composition of the present invention treatment western babesiasis of horse BABEI：Desinsection removing toxic substances, heat-clearing and damp-drying drug, tonifying Qi Blood-nourishing, nourishing Yin and promoting production of body fluid.

Fang Xie：With kuh-seng, sweet wormwood as main ingredient in side, matrine, artesunate are contained in main ingredient, tool has anti-Shang worms, amoeba former Worm acts on, and has very high inhibition killing action to cruel protozoon, burnt worm；The coptis is processed with subdigitate wormwood herb, madder, Semi-pinnated Brake Herb, radix berberidis, ginger Be adjuvant, in adjuvant nature and flavor be generally it is bitter, cold, it is bitter can eliminating dampness, tremble with fear can heat-clearing, therefore have functions that heat-clearing and damp-drying drug, and can clearing heat-fire, Hyperpyrexia caused by treatment babesiasis, liver and gallbladder damp-heat Yellow subcutaneous ulcers, intestines Huang diarrhea；Fried with dutchmanspipe root, Amomum cardamomum, safflower, salt Tsaoko, conic gymnadenia tuber, umbrella handle kiss-me, the root of straight ladybell is processed for adjutant, strengthening the spleen and stomach, benefiting qi and nourishing blood, nourishing Yin and promoting production of body fluid, the nourishing thin and weak body of sick horse Matter strengthen immunity, clears up the toxic and side effect for producing hemotoxin in blood intracellular metabolite by burnt worm polypide, improves sick horse seriously poor Mass formed by blood stasis shape, while with Amomum cardamomum using its pungent, warm property as using corrigent in adjutant, with the cold and cool property of medicine in the side of restriction；With Radix Glycyrrhizae (processed with honey) restrains coordinating the drug actions of a prescription to make medicine.More than each medicine with its, each effect cooperates that to eliminate burnt worm secondary to the poison of body Effect, plays desinsection removing toxic substances altogether, and clearing heat and cooling blood, the work(of blood-nourishing nourishing reach and kills the purpose that polypide cures babesiasis.

The beneficial effect of the present invention and prior art：Traditional Chinese medicine composition of the invention overcomes prior art not A kind of foot, there is provided the Traditional Chinese medicine composition formula of high, the safe and reliable treatment equine piroplasmosis of evident in efficacy, instant effect, healing.

Mostly based on chemical drug, medicine residence time in carcass is long, holds for prior art treatment equine piroplasmosis pharmaceutical compositions The phenomena of mortality easily are accumulated poisoning, the invention provides a kind of drug effect safety, the new medicine composition having no toxic side effect.

The Chinese medicine composition of the invention difference maximum with prior art is, due to long-term use chemotherapy domestic animal Parasitic disease, chemicals is in carcass and cannot fully absorb decomposition by carcass, can produce toxic and side effect, the excreta of sick horse Environment can be polluted, the present composition is pure Chinese medicinal preparation, drug effect is easily decomposed absorption, excreta is not caused to environment Pollution.

The present composition changes old medication idea in control and prevention of disease, and treatment animal parasite disease uses chemical drugs less Product, use Chinese medicine preparation instead, because many Chinese medicine preparations all have desinsection, parasite elimination, removing toxic substances, anti-inflammatory, the function of enhance immunity, can Desinsection toxin expelling by substitute Western medicine chemicals, Chinese medicinal material raw material, strengthens animal body immunologic function, again can be as spy Bioactive additive is planted, the new katabolism of body is adjusted, promotes the absorption of nutriment, improve domestic animal resistance against diseases.

Treatment by Chinese herbs equine piroplasmosis is used, the compound preparation of personalization is used, there is specific aim to illness, treated The diversification of Effective Component of Chinese Medicine in journey, burnt worm polypide is difficult to produce it drug resistance, and kuh-seng is contained in present composition main ingredient Alkali, qinghaosu, Ju You Kang Shang worms, Amoeba effect to cruel protozoon, burnt worm, have very high inhibition to act on, desinsection removing toxic substances, Toxicity, the sick horse of improvement of heat-clearing and damp-drying drug, benefiting qi and nourishing blood, nourishing Yin and promoting production of body fluid, removing caused by polypide metabolism produces hemotoxin Anemia, recovers sick horse resistance, and healing equine piroplasmosis for the treatment of both principal and secondary aspect of disease is carried out with reference to modern inspection technology over the course for the treatment of Checking, determined curative effect, clinical practice is without any side effects.

Specific embodiment

Preferred embodiment 1

The Chinese medicine composition of the treatment western babesiasis of horse BABEI of this specific embodiment, is constituted by following weight portion：Kuh-seng 40 parts, 40 parts of sweet wormwood, 40 parts of subdigitate wormwood herb, 40 parts of madder, 30 parts of Semi-pinnated Brake Herb, 40 parts of barberry, ginger process 10 parts of the coptis, dutchmanspipe root 40 Part, 20 parts of Amomum cardamomum, 5 parts of safflower, 25 parts of salt stir-baked FRUCTUS TSAOKO, 90 parts of conic gymnadenia tuber, 20 parts of umbrella handle kiss-me, honey process 40 parts of the root of straight ladybell, 15 parts of Radix Glycyrrhizae (processed with honey).

Preparation method one

40 parts of kuh-seng, 40 parts of sweet wormwood, 40 parts of subdigitate wormwood herb, 40 parts of madder, 30 parts of Semi-pinnated Brake Herb, 40 parts of barberry, ginger are processed into Huang 10 parts of company, 40 parts of dutchmanspipe root, 20 parts of Amomum cardamomum, 5 parts of safflower, 25 parts of salt stir-baked FRUCTUS TSAOKO, 90 parts of conic gymnadenia tuber, umbrella handle kiss-me 20 Part, honey process 40 parts of the root of straight ladybell, 15 parts of Radix Glycyrrhizae (processed with honey), and every part of active compound quality is one gram, and size-reduced machine is crushed, and it is anti-to cross 100 mesh sieve Answered pulverizer to crush 5 times, medicine was well mixed, and be put into container or polybag and seal standby.

Preparation method two

Step one, mixing, immersion：By 40 parts of kuh-seng, 40 parts of sweet wormwood, 40 parts of subdigitate wormwood herb, 40 parts of madder, 30 parts of Semi-pinnated Brake Herb, 40 parts of barberry, ginger process 10 parts of the coptis, 40 parts of dutchmanspipe root, 20 parts of Amomum cardamomum, 5 parts of safflower, 25 parts of salt stir-baked FRUCTUS TSAOKO, conic gymnadenia tuber 90 Part, 20 parts of umbrella handle kiss-me, honey are processed 40 parts of the root of straight ladybell, 15 parts of Radix Glycyrrhizae (processed with honey) and are well mixed, and every part of active compound quality is one gram, immersion： Each raw material is weighed by above-mentioned mass ratio, gross weight is designated as 1 part, add 6 parts of purified waters, 40-50 DEG C of immersion 1h makes medicinal material fully swollen It is swollen；

Step 2, extraction：Using decocting method twice, by medicinal material and purified water in step one, the steam pressure is controlled to be 0.1-0.2MPa, after being heated to boiling, continues to boil 2h；

Fried liquid is taken out in step 3, separation, continues to the purified water that 4 parts are added in medicinal material, and it is 0.1- to control steam pressure 0.2MPa, after being heated to boiling, continues to boil 1.5h, merges fried liquid twice and is extract solution；

Step 4, concentration：Concentrated during obtained extract solution in step 2 is added into economic benefits and social benefits concentration tank, vacuum concentration is steamed Steam pressure is 0.1MPa, and an effect vacuum concentrator operating pressure is 0.04MPa, and temperature is 80 DEG C；Two effect inspissator operating pressures 0.06MPa, temperature is 65 DEG C, and concentration time is 2.5-3.5h, when heat surveys relative density for 1.17-1.20, obtains concentrate；

Step 5, alcohol precipitation：Concentrate is placed in Alcohol-settling tank, to 95% ethanol is slowly added in Alcohol-settling tank, contains ethanol It is 65%-70% to measure, and stirs 30min, and 4 DEG C of refrigerations stand 48h, are concentrated under reduced pressure into relative density for 1.40-1.50, reclaim second Alcohol, that is, obtain alcohol extracting liquid；

Step 6, with liquid：To 0.3-0.4 parts of purified water is added in Agitation Tank, gained alcohol in step 4 is then sequentially added Extract solution, 0.003 part of Sodium Benzoate, stirring to fully dissolving, the amount for adding purified water to be settled to 1 part stir 15min, system The traditional Chinese medicine oral liquid of equine piroplasmosis must be treated.

Preparation method three

Step one, by 40 parts of kuh-seng, 40 parts of sweet wormwood, 40 parts of subdigitate wormwood herb, 40 parts of madder, 30 parts of Semi-pinnated Brake Herb, 40 parts of barberry, Ginger processs 10 parts of the coptis, 40 parts of dutchmanspipe root, 20 parts of Amomum cardamomum, 5 parts of safflower, 25 parts of salt stir-baked FRUCTUS TSAOKO, 90 parts of conic gymnadenia tuber, umbrella handle tiger ear 20 parts of grass, honey are processed 40 parts of the root of straight ladybell, 15 parts of Radix Glycyrrhizae (processed with honey) and are well mixed, and every part of active compound quality is one gram, and active compound gross mass is designated as 1 Part, plus the decocting of 10 times of weight boiled 3 hours, and the decocting of second plus 7 times of weight is boiled 2 hours, will twice decoction liquor with 3 layers of gauze Filtration, merging filtrate concentrates the filtrate to the thick paste that relative density is 1.26-1.36 (50 DEG C), and spray drying obtains dry extract；

Step 2, dry extract is taken, add appropriate lactose, be well mixed, dry-pressing loads capsule into particle.

The usage and dosage of Chinese medicine composition of the present invention：The usage and dosage of capsule preparations：By sick horse body weight 3g/kg, feed every Day 1 time, it is used in conjunction 6-12 days.The usage and dosage of oral liquid formulations：By horse body weight 3ml/kg, one time a day to throw clothes with stomach tube, is used in conjunction 6- 12 days.Or according to present embodiment Chinese medicine composition said ratio relation by Chinese medicine composition mix immersion after, with decoct Chinese medicinal decoction is obtained after pot infusion, by stomach tube to disease after the Chinese medicinal decoction of body weight and the state of an illness selection doses according to ill domestic animal Poultry is directly gavaged, and one time a day, is used in conjunction 6-12 days.

Preferred embodiment 2

The Chinese medicine composition of the treatment western babesiasis of horse BABEI of this specific embodiment, constitutes by weight：65 parts of kuh-seng, 60 parts of sweet wormwood, 60 parts of subdigitate wormwood herb, 60 parts of madder, 50 parts of Semi-pinnated Brake Herb, 60 parts of barberry, ginger process 30 parts of the coptis, 60 parts of dutchmanspipe root, white 40 parts of cardamom, 20 parts of safflower, 45 parts of salt stir-baked FRUCTUS TSAOKO, 110 parts of conic gymnadenia tuber, 40 parts of umbrella handle kiss-me, honey are processed 60 parts of the root of straight ladybell, honey and are processed 30 parts of Radix Glycyrrhizae.

Preparation method one

65 parts of kuh-seng, 60 parts of sweet wormwood, 60 parts of subdigitate wormwood herb, 60 parts of madder, 50 parts of Semi-pinnated Brake Herb, 60 parts of barberry, ginger are processed into Huang 30 parts of company, 60 parts of dutchmanspipe root, 40 parts of Amomum cardamomum, 20 parts of safflower, 45 parts of salt stir-baked FRUCTUS TSAOKO, 110 parts of conic gymnadenia tuber, umbrella handle kiss-me 40 Part, honey process 60 parts of the root of straight ladybell, 30 parts of Radix Glycyrrhizae (processed with honey), and every part of active compound quality is one gram, and size-reduced machine is crushed, and it is anti-to cross 100 mesh sieve Answered pulverizer to crush 5 times, medicine was well mixed, and be put into container or polybag and seal standby.

Preparation method two

Step one, mixing, immersion：By 65 parts of kuh-seng, 60 parts of sweet wormwood, 60 parts of subdigitate wormwood herb, 60 parts of madder, 50 parts of Semi-pinnated Brake Herb, 60 parts of barberry, ginger process 30 parts of the coptis, 60 parts of dutchmanspipe root, 40 parts of Amomum cardamomum, 20 parts of safflower, 45 parts of salt stir-baked FRUCTUS TSAOKO, conic gymnadenia tuber 110 parts, 40 parts of umbrella handle kiss-me, honey process 60 parts of the root of straight ladybell, 30 parts of Radix Glycyrrhizae (processed with honey) and be well mixed, every part of active compound quality is one gram, leaching Bubble：Each raw material is weighed by above-mentioned mass ratio, gross weight is designated as 1 part, add 6 parts of purified waters, 40-50 DEG C of immersion 1h fills medicinal material Divide expansion；

Step 5, alcohol precipitation：Concentrate is placed in Alcohol-settling tank, to 95% ethanol is slowly added in Alcohol-settling tank, contains ethanol It is 65%-70% to measure, and stirs 30min, and 4 DEG C of refrigerations stand 48h, are concentrated under reduced pressure into relative density for 1.40-1.50, reclaim second Alcohol, that is, obtain alcohol extracting liquid；Step 6, with liquid：To 0.3-0.4 parts of purified water is added in Agitation Tank, step is then sequentially added Gained alcohol extract, 0.003 part of Sodium Benzoate in rapid four, stirring to fully dissolving, the amount for adding purified water to be settled to 1 part, Stirring 15min, is obtained the traditional Chinese medicine oral liquid for the treatment of equine piroplasmosis.

Preparation method three

Step one, by 65 parts of kuh-seng, 60 parts of sweet wormwood, 60 parts of subdigitate wormwood herb, 60 parts of madder, 50 parts of Semi-pinnated Brake Herb, 60 parts of barberry, Ginger processs 30 parts of the coptis, 60 parts of dutchmanspipe root, 40 parts of Amomum cardamomum, 20 parts of safflower, 45 parts of salt stir-baked FRUCTUS TSAOKO, 110 parts of conic gymnadenia tuber, umbrella handle tiger 40 parts of Auricled Hedyotis Herb, honey are processed 60 parts of the root of straight ladybell, 30 parts of Radix Glycyrrhizae (processed with honey) and are well mixed, and every part of active compound quality is one gram, and active compound gross mass is designated as 1 Part, plus the decocting of 10 times of weight boiled 3 hours, and the decocting of second plus 7 times of weight is boiled 2 hours, will twice decoction liquor with 3 layers of gauze Filtration, merging filtrate concentrates the filtrate to the thick paste that relative density is 1.26-1.36 (50 DEG C), and spray drying obtains dry extract；

Preferred embodiment 3

The Chinese medicine composition of the treatment western babesiasis of horse BABEI of this specific embodiment, constitutes by weight：43 parts of kuh-seng, 42 parts of sweet wormwood, 43 parts of subdigitate wormwood herb, 44 parts of madder, 32 parts of Semi-pinnated Brake Herb, 43 parts of barberry, ginger process 12 parts of the coptis, 43 parts of dutchmanspipe root, white 22 parts of cardamom, 7 parts of safflower, 28 parts of salt stir-baked FRUCTUS TSAOKO, 93 parts of conic gymnadenia tuber, 23 parts of umbrella handle kiss-me, honey process 42 parts of the root of straight ladybell, honey process it is sweet 17 parts of grass.

Preparation method one

43 parts of kuh-seng, 42 parts of sweet wormwood, 43 parts of subdigitate wormwood herb, 44 parts of madder, 32 parts of Semi-pinnated Brake Herb, 43 parts of barberry, ginger are processed into Huang 12 parts of company, 43 parts of dutchmanspipe root, 22 parts of Amomum cardamomum, 7 parts of safflower, 28 parts of salt stir-baked FRUCTUS TSAOKO, 93 parts of conic gymnadenia tuber, umbrella handle kiss-me 23 Part, honey process 42 parts of the root of straight ladybell, 17 parts of Radix Glycyrrhizae (processed with honey), and every part of active compound quality is one gram, and size-reduced machine is crushed, and it is anti-to cross 100 mesh sieve Answered pulverizer to crush 5 times, medicine was well mixed, and be put into container or polybag and seal standby.

Preparation method two

Step one, mixing, immersion：By 43 parts of kuh-seng, 42 parts of sweet wormwood, 43 parts of subdigitate wormwood herb, 44 parts of madder, 32 parts of Semi-pinnated Brake Herb, 43 parts of barberry, ginger process 12 parts of the coptis, 43 parts of dutchmanspipe root, 22 parts of Amomum cardamomum, 7 parts of safflower, 28 parts of salt stir-baked FRUCTUS TSAOKO, conic gymnadenia tuber 93 Part, 23 parts of umbrella handle kiss-me, honey are processed 42 parts of the root of straight ladybell, 17 parts of Radix Glycyrrhizae (processed with honey) and are well mixed, and every part of active compound quality is one gram, immersion： Each raw material is weighed by above-mentioned mass ratio, gross weight is designated as 1 part, add 6 parts of purified waters, 40-50 DEG C of immersion 1h makes medicinal material fully swollen It is swollen；

Preparation method three

Step one, by 43 parts of kuh-seng, 42 parts of sweet wormwood, 43 parts of subdigitate wormwood herb, 44 parts of madder, 32 parts of Semi-pinnated Brake Herb, 43 parts of barberry, Ginger processs 12 parts of the coptis, 43 parts of dutchmanspipe root, 22 parts of Amomum cardamomum, 7 parts of safflower, 28 parts of salt stir-baked FRUCTUS TSAOKO, 93 parts of conic gymnadenia tuber, umbrella handle tiger ear 23 parts of grass, honey are processed 42 parts of the root of straight ladybell, 17 parts of Radix Glycyrrhizae (processed with honey) and are well mixed, and every part of active compound quality is one gram, and active compound gross mass is designated as 1 Part, plus the decocting of 10 times of weight boiled 3 hours, and the decocting of second plus 7 times of weight is boiled 2 hours, will twice decoction liquor with 3 layers of gauze Filtration, merging filtrate concentrates the filtrate to the thick paste that relative density is 1.26-1.36 (50 DEG C), and spray drying obtains dry extract；

Preferred embodiment 4

The Chinese medicine composition of the treatment western babesiasis of horse BABEI of this specific embodiment, constitutes by weight：45 parts of kuh-seng, 44 parts of sweet wormwood, 46 parts of subdigitate wormwood herb, 47 parts of madder, 35 parts of Semi-pinnated Brake Herb, 45 parts of barberry, ginger process 15 parts of the coptis, 46 parts of dutchmanspipe root, white 24 parts of cardamom, 9 parts of safflower, 30 parts of salt stir-baked FRUCTUS TSAOKO, 96 parts of conic gymnadenia tuber, 25 parts of umbrella handle kiss-me, honey process 45 parts of the root of straight ladybell, honey process it is sweet 19 parts of grass.

Preparation method one

45 parts of kuh-seng, 44 parts of sweet wormwood, 46 parts of subdigitate wormwood herb, 47 parts of madder, 35 parts of Semi-pinnated Brake Herb, 45 parts of barberry, ginger are processed into Huang 15 parts of company, 46 parts of dutchmanspipe root, 24 parts of Amomum cardamomum, 9 parts of safflower, 30 parts of salt stir-baked FRUCTUS TSAOKO, 96 parts of conic gymnadenia tuber, umbrella handle kiss-me 25 Part, honey process 45 parts of the root of straight ladybell, 19 parts of Radix Glycyrrhizae (processed with honey), and every part of active compound quality is one gram, and size-reduced machine is crushed, and it is anti-to cross 100 mesh sieve Answered pulverizer to crush 5 times, medicine was well mixed, and be put into container or polybag and seal standby.

Preparation method two

Step one, mixing, immersion：By 45 parts of kuh-seng, 44 parts of sweet wormwood, 46 parts of subdigitate wormwood herb, 47 parts of madder, 35 parts of Semi-pinnated Brake Herb, 45 parts of barberry, ginger process 15 parts of the coptis, 46 parts of dutchmanspipe root, 24 parts of Amomum cardamomum, 9 parts of safflower, 30 parts of salt stir-baked FRUCTUS TSAOKO, conic gymnadenia tuber 96 Part, 25 parts of umbrella handle kiss-me, honey are processed 45 parts of the root of straight ladybell, 19 parts of Radix Glycyrrhizae (processed with honey) and are well mixed, and every part of active compound quality is one gram, immersion： Each raw material is weighed by above-mentioned mass ratio, gross weight is designated as 1 part, add 6 parts of purified waters, 40-50 DEG C of immersion 1h makes medicinal material fully swollen It is swollen；

Step 5, alcohol precipitation：Concentrate is placed in Alcohol-settling tank, to 95% ethanol is slowly added in Alcohol-settling tank, contains ethanol It is 65%-70% to measure, and stirs 30min, and 4 DEG C of refrigerations stand 48h, are concentrated under reduced pressure into relative density for 1.40-1.50, reclaim second Alcohol, that is, obtain alcohol extracting liquid；Step 6, with liquid：To 0.3-0.4 parts of purified water is added in Agitation Tank, step is then sequentially added Gained alcohol extract, 0.003 part of Sodium Benzoate in rapid four, stirring to fully dissolving, the amount for adding purified water to be settled to 1 part, Stirring 15min, is obtained the traditional Chinese medicine oral liquid for the treatment of equine piroplasmosis；

Preparation method three

Step one, by 45 parts of kuh-seng, 44 parts of sweet wormwood, 46 parts of subdigitate wormwood herb, 47 parts of madder, 35 parts of Semi-pinnated Brake Herb, 45 parts of barberry, Ginger processs 15 parts of the coptis, 46 parts of dutchmanspipe root, 24 parts of Amomum cardamomum, 9 parts of safflower, 30 parts of salt stir-baked FRUCTUS TSAOKO, 96 parts of conic gymnadenia tuber, umbrella handle tiger ear 25 parts of grass, honey are processed 45 parts of the root of straight ladybell, 19 parts of Radix Glycyrrhizae (processed with honey) and are well mixed, and every part of active compound quality is one gram, and active compound gross mass is designated as 1 Part, plus the decocting of 10 times of weight boiled 3 hours, and the decocting of second plus 7 times of weight is boiled 2 hours, will twice decoction liquor with 3 layers of gauze Filtration, merging filtrate concentrates the filtrate to the thick paste that relative density is 1.26-1.36 (50 DEG C), and spray drying obtains dry extract；

Preferred embodiment 5

The Chinese medicine composition of the treatment western babesiasis of horse BABEI of this specific embodiment, constitutes by weight：49 parts of kuh-seng, 48 parts of sweet wormwood, 49 parts of subdigitate wormwood herb, 48 parts of madder, 37 parts of Semi-pinnated Brake Herb, 48 parts of barberry, ginger process 18 parts of the coptis, 49 parts of dutchmanspipe root, white 27 parts of cardamom, 11 parts of safflower, 33 parts of salt stir-baked FRUCTUS TSAOKO, 98 parts of conic gymnadenia tuber, 29 parts of umbrella handle kiss-me, honey are processed 48 parts of the root of straight ladybell, honey and are processed 22 parts of Radix Glycyrrhizae.

Preparation method one

49 parts of kuh-seng, 48 parts of sweet wormwood, 49 parts of subdigitate wormwood herb, 48 parts of madder, 37 parts of Semi-pinnated Brake Herb, 48 parts of barberry, ginger are processed into Huang 18 parts of company, 49 parts of dutchmanspipe root, 27 parts of Amomum cardamomum, 11 parts of safflower, 33 parts of salt stir-baked FRUCTUS TSAOKO, 98 parts of conic gymnadenia tuber, umbrella handle kiss-me 29 Part, honey process 48 parts of the root of straight ladybell, 22 parts of Radix Glycyrrhizae (processed with honey), and every part of active compound quality is one gram, and size-reduced machine is crushed, and it is anti-to cross 100 mesh sieve Answered pulverizer to crush 5 times, medicine was well mixed, and be put into container or polybag and seal standby.

Preparation method two

Step one, mixing, immersion：By 49 parts of kuh-seng, 48 parts of sweet wormwood, 49 parts of subdigitate wormwood herb, 48 parts of madder, 37 parts of Semi-pinnated Brake Herb, 48 parts of barberry, ginger process 18 parts of the coptis, 49 parts of dutchmanspipe root, 27 parts of Amomum cardamomum, 11 parts of safflower, 33 parts of salt stir-baked FRUCTUS TSAOKO, conic gymnadenia tuber 98 parts, 29 parts of umbrella handle kiss-me, honey process 48 parts of the root of straight ladybell, 22 parts of Radix Glycyrrhizae (processed with honey) and be well mixed, every part of active compound quality is portion, leaching Bubble：Each raw material is weighed by above-mentioned mass ratio, gross weight is designated as 1 part, add 6 parts of purified waters, 40-50 DEG C of immersion 1h fills medicinal material Divide expansion；

Preparation method three

Step one, by 49 parts of kuh-seng, 48 parts of sweet wormwood, 49 parts of subdigitate wormwood herb, 48 parts of madder, 37 parts of Semi-pinnated Brake Herb, 48 parts of barberry, Ginger processs 18 parts of the coptis, 49 parts of dutchmanspipe root, 27 parts of Amomum cardamomum, 11 parts of safflower, 33 parts of salt stir-baked FRUCTUS TSAOKO, 98 parts of conic gymnadenia tuber, umbrella handle tiger 29 parts of Auricled Hedyotis Herb, honey are processed 48 parts of the root of straight ladybell, 22 parts of Radix Glycyrrhizae (processed with honey) and are well mixed, and every part of active compound quality is one gram, and active compound gross mass is designated as 1 Part, plus the decocting of 10 times of weight boiled 3 hours, and the decocting of second plus 7 times of weight is boiled 2 hours, will twice decoction liquor with 3 layers of gauze Filtration, merging filtrate concentrates the filtrate to the thick paste that relative density is 1.26-1.36 (50 DEG C), and spray drying obtains dry extract；

Preferred embodiment 6

The Chinese medicine composition of the treatment western babesiasis of horse BABEI of this specific embodiment, constitutes by weight：52 parts of kuh-seng, 50 parts of sweet wormwood, 51 parts of subdigitate wormwood herb, 50 parts of madder, 40 parts of Semi-pinnated Brake Herb, 50 parts of barberry, ginger process 21 parts of the coptis, 52 parts of dutchmanspipe root, white 29 parts of cardamom, 13 parts of safflower, 38 parts of salt stir-baked FRUCTUS TSAOKO, 100 parts of conic gymnadenia tuber, 32 parts of umbrella handle kiss-me, honey are processed 50 parts of the root of straight ladybell, honey and are processed 24 parts of Radix Glycyrrhizae.

Preparation method one

52 parts of kuh-seng, 50 parts of sweet wormwood, 51 parts of subdigitate wormwood herb, 50 parts of madder, 40 parts of Semi-pinnated Brake Herb, 50 parts of barberry, ginger are processed into Huang 21 parts of company, 52 parts of dutchmanspipe root, 29 parts of Amomum cardamomum, 13 parts of safflower, 38 parts of salt stir-baked FRUCTUS TSAOKO, 100 parts of conic gymnadenia tuber, umbrella handle kiss-me 32 Part, honey process 50 parts of the root of straight ladybell, 24 parts of Radix Glycyrrhizae (processed with honey), and every part of active compound quality is one gram, and size-reduced machine is crushed, and it is anti-to cross 100 mesh sieve Answered pulverizer to crush 5 times, medicine was well mixed, and be put into container or polybag and seal standby.

Preparation method two

Step one, mixing, immersion：By 52 parts of kuh-seng, 50 parts of sweet wormwood, 51 parts of subdigitate wormwood herb, 50 parts of madder, 40 parts of Semi-pinnated Brake Herb, 50 parts of barberry, ginger process 21 parts of the coptis, 52 parts of dutchmanspipe root, 29 parts of Amomum cardamomum, 13 parts of safflower, 38 parts of salt stir-baked FRUCTUS TSAOKO, conic gymnadenia tuber 100 parts, 32 parts of umbrella handle kiss-me, honey process 50 parts of the root of straight ladybell, 24 parts of Radix Glycyrrhizae (processed with honey) and be well mixed, every part of active compound quality is portion, leaching Bubble：Each raw material is weighed by above-mentioned mass ratio, gross weight is designated as 1 part, add 6 parts of purified waters, 40-50 DEG C of immersion 1h fills medicinal material Divide expansion；

Preparation method three

Step one, by 52 parts of kuh-seng, 50 parts of sweet wormwood, 51 parts of subdigitate wormwood herb, 50 parts of madder, 40 parts of Semi-pinnated Brake Herb, 50 parts of barberry, Ginger processs 21 parts of the coptis, 52 parts of dutchmanspipe root, 29 parts of Amomum cardamomum, 13 parts of safflower, 38 parts of salt stir-baked FRUCTUS TSAOKO, 100 parts of conic gymnadenia tuber, umbrella handle tiger 32 parts of Auricled Hedyotis Herb, honey are processed 50 parts of the root of straight ladybell, 24 parts of Radix Glycyrrhizae (processed with honey) and are well mixed, and every part of active compound quality is one gram, and active compound gross mass is designated as 1 Part, plus the decocting of 10 times of weight boiled 3 hours, and the decocting of second plus 7 times of weight is boiled 2 hours, will twice decoction liquor with 3 layers of gauze Filtration, merging filtrate concentrates the filtrate to the thick paste that relative density is 1.26-1.36 (50 DEG C), and spray drying obtains dry extract；

Preferred embodiment 7

The Chinese medicine composition of the treatment western babesiasis of horse BABEI of this specific embodiment, constitutes by weight：54 parts of kuh-seng, 52 parts of sweet wormwood, 53 parts of subdigitate wormwood herb, 52 parts of madder, 42 parts of Semi-pinnated Brake Herb, 53 parts of barberry, ginger process 23 parts of the coptis, 54 parts of dutchmanspipe root, white 31 parts of cardamom, 15 parts of safflower, 42 parts of salt stir-baked FRUCTUS TSAOKO, 102 parts of conic gymnadenia tuber, 34 parts of umbrella handle kiss-me, honey are processed 52 parts of the root of straight ladybell, honey and are processed 26 parts of Radix Glycyrrhizae.

Preparation method one

54 parts of kuh-seng, 52 parts of sweet wormwood, 53 parts of subdigitate wormwood herb, 52 parts of madder, 42 parts of Semi-pinnated Brake Herb, 53 parts of barberry, ginger are processed into Huang 23 parts of company, 54 parts of dutchmanspipe root, 31 parts of Amomum cardamomum, 15 parts of safflower, 42 parts of salt stir-baked FRUCTUS TSAOKO, 102 parts of conic gymnadenia tuber, umbrella handle kiss-me 34 Part, honey process 52 parts of the root of straight ladybell, 26 parts of Radix Glycyrrhizae (processed with honey), and every part of active compound quality is one gram, and size-reduced machine is crushed, and it is anti-to cross 100 mesh sieve Answered pulverizer to crush 5 times, medicine was well mixed, and be put into container or polybag and seal standby.

Preparation method two

Step one, mixing, immersion：By 54 parts of kuh-seng, 52 parts of sweet wormwood, 53 parts of subdigitate wormwood herb, 52 parts of madder, 42 parts of Semi-pinnated Brake Herb, 53 parts of barberry, ginger process 23 parts of the coptis, 54 parts of dutchmanspipe root, 31 parts of Amomum cardamomum, 15 parts of safflower, 42 parts of salt stir-baked FRUCTUS TSAOKO, conic gymnadenia tuber 102 parts, 34 parts of umbrella handle kiss-me, honey process 52 parts of the root of straight ladybell, 26 parts of Radix Glycyrrhizae (processed with honey) and be well mixed, every part of active compound quality is portion, leaching Bubble：Each raw material is weighed by above-mentioned mass ratio, gross weight is designated as 1 part, add 6 parts of purified waters, 40-50 DEG C of immersion 1h fills medicinal material Divide expansion；

Preparation method three

Step one, by 54 parts of kuh-seng, 52 parts of sweet wormwood, 53 parts of subdigitate wormwood herb, 52 parts of madder, 42 parts of Semi-pinnated Brake Herb, 53 parts of barberry, Ginger processs 23 parts of the coptis, 54 parts of dutchmanspipe root, 31 parts of Amomum cardamomum, 15 parts of safflower, 42 parts of salt stir-baked FRUCTUS TSAOKO, 102 parts of conic gymnadenia tuber, umbrella handle tiger 34 parts of Auricled Hedyotis Herb, honey are processed 52 parts of the root of straight ladybell, 26 parts of Radix Glycyrrhizae (processed with honey) and are well mixed, and every part of active compound quality is one gram, and active compound gross mass is designated as 1 Part, plus the decocting of 10 times of weight boiled 3 hours, and the decocting of second plus 7 times of weight is boiled 2 hours, will twice decoction liquor with 3 layers of gauze Filtration, merging filtrate concentrates the filtrate to the thick paste that relative density is 1.26-1.36 (50 DEG C), and spray drying obtains dry extract；

Preferred embodiment 8

The Chinese medicine composition of the treatment western babesiasis of horse BABEI of this specific embodiment, constitutes by weight：56 parts of kuh-seng, 54 parts of sweet wormwood, 55 parts of subdigitate wormwood herb, 54 parts of madder, 45 parts of Semi-pinnated Brake Herb, 56 parts of barberry, ginger process 26 parts of the coptis, 56 parts of dutchmanspipe root, white 35 parts of cardamom, 17 parts of safflower, 43 parts of salt stir-baked FRUCTUS TSAOKO, 105 parts of conic gymnadenia tuber, 36 parts of umbrella handle kiss-me, honey are processed 54 parts of the root of straight ladybell, honey and are processed 28 parts of Radix Glycyrrhizae.

Preparation method one

56 parts of kuh-seng, 54 parts of sweet wormwood, 55 parts of subdigitate wormwood herb, 54 parts of madder, 45 parts of Semi-pinnated Brake Herb, 56 parts of barberry, ginger are processed into Huang 26 parts of company, 56 parts of dutchmanspipe root, 35 parts of Amomum cardamomum, 17 parts of safflower, 43 parts of salt stir-baked FRUCTUS TSAOKO, 105 parts of conic gymnadenia tuber, umbrella handle kiss-me 36 Part, honey process 54 parts of the root of straight ladybell, 28 parts of Radix Glycyrrhizae (processed with honey), and every part of active compound quality is one gram, and size-reduced machine is crushed, and it is anti-to cross 100 mesh sieve Answered pulverizer to crush 5 times, medicine was well mixed, and be put into container or polybag and seal standby.

Preparation method two

Step one, mixing, immersion：By 56 parts of kuh-seng, 54 parts of sweet wormwood, 55 parts of subdigitate wormwood herb, 54 parts of madder, 45 parts of Semi-pinnated Brake Herb, 56 parts of barberry, ginger process 26 parts of the coptis, 56 parts of dutchmanspipe root, 35 parts of Amomum cardamomum, 17 parts of safflower, 43 parts of salt stir-baked FRUCTUS TSAOKO, conic gymnadenia tuber 105 parts, 36 parts of umbrella handle kiss-me, honey process 54 parts of the root of straight ladybell, 28 parts of Radix Glycyrrhizae (processed with honey) and be well mixed, every part of active compound quality is portion, leaching Bubble：Each raw material is weighed by above-mentioned mass ratio, gross weight is designated as 1 part, add 6 parts of purified waters, 40-50 DEG C of immersion 1h fills medicinal material Divide expansion；

Preparation method three

Step one, by 56 parts of kuh-seng, 54 parts of sweet wormwood, 55 parts of subdigitate wormwood herb, 54 parts of madder, 45 parts of Semi-pinnated Brake Herb, 56 parts of barberry, Ginger processs 26 parts of the coptis, 56 parts of dutchmanspipe root, 35 parts of Amomum cardamomum, 17 parts of safflower, 43 parts of salt stir-baked FRUCTUS TSAOKO, 105 parts of conic gymnadenia tuber, umbrella handle tiger 36 parts of Auricled Hedyotis Herb, honey are processed 54 parts of the root of straight ladybell, 28 parts of Radix Glycyrrhizae (processed with honey) and are well mixed, and every part of active compound quality is one gram, and active compound gross mass is designated as 1 Part, plus the decocting of 10 times of weight boiled 3 hours, and the decocting of second plus 7 times of weight is boiled 2 hours, will twice decoction liquor with 3 layers of gauze Filtration, merging filtrate concentrates the filtrate to the thick paste that relative density is 1.26-1.36 (50 DEG C), and spray drying obtains dry extract；

Preferred embodiment 9

The Chinese medicine composition of the treatment western babesiasis of horse BABEI of this specific embodiment, constitutes by weight：58 parts of kuh-seng, 56 parts of sweet wormwood, 57 parts of subdigitate wormwood herb, 58 parts of madder, 48 parts of Semi-pinnated Brake Herb, 58 parts of barberry, ginger process 28 parts of the coptis, 58 parts of dutchmanspipe root, white 38 parts of cardamom, 19 parts of safflower, 44 parts of salt stir-baked FRUCTUS TSAOKO, 108 parts of conic gymnadenia tuber, 38 parts of umbrella handle kiss-me, honey are processed 56 parts of the root of straight ladybell, honey and are processed 24 parts of Radix Glycyrrhizae.

Preparation method one

58 parts of kuh-seng, 56 parts of sweet wormwood, 57 parts of subdigitate wormwood herb, 58 parts of madder, 48 parts of Semi-pinnated Brake Herb, 58 parts of barberry, ginger are processed into Huang 28 parts of company, 58 parts of dutchmanspipe root, 38 parts of Amomum cardamomum, 19 parts of safflower, 44 parts of salt stir-baked FRUCTUS TSAOKO, 108 parts of conic gymnadenia tuber, umbrella handle kiss-me 38 Part, honey process 56 parts of the root of straight ladybell, 24 parts of Radix Glycyrrhizae (processed with honey), and every part of active compound quality is one gram, and size-reduced machine is crushed, and it is anti-to cross 100 mesh sieve Answered pulverizer to crush 5 times, medicine was well mixed, and be put into container or polybag and seal standby.

Preparation method two

Step one, mixing, immersion：By 58 parts of kuh-seng, 56 parts of sweet wormwood, 57 parts of subdigitate wormwood herb, 58 parts of madder, 48 parts of Semi-pinnated Brake Herb, 58 parts of barberry, ginger process 28 parts of the coptis, 58 parts of dutchmanspipe root, 38 parts of Amomum cardamomum, 19 parts of safflower, 44 parts of salt stir-baked FRUCTUS TSAOKO, conic gymnadenia tuber 108 parts, 38 parts of umbrella handle kiss-me, honey process 56 parts of the root of straight ladybell, 24 parts of Radix Glycyrrhizae (processed with honey) and be well mixed, every part of active compound quality is portion, leaching Bubble：Each raw material is weighed by above-mentioned mass ratio, gross weight is designated as 1 part, add 6 parts of purified waters, 40-50 DEG C of immersion 1h fills medicinal material Divide expansion；

Preparation method three

Step one, by 58 parts of kuh-seng, 56 parts of sweet wormwood, 57 parts of subdigitate wormwood herb, 58 parts of madder, 48 parts of Semi-pinnated Brake Herb, 58 parts of barberry, Ginger processs 28 parts of the coptis, 58 parts of dutchmanspipe root, 38 parts of Amomum cardamomum, 19 parts of safflower, 44 parts of salt stir-baked FRUCTUS TSAOKO, 108 parts of conic gymnadenia tuber, umbrella handle tiger 38 parts of Auricled Hedyotis Herb, honey are processed 56 parts of the root of straight ladybell, 24 parts of Radix Glycyrrhizae (processed with honey) and are well mixed, and every part of active compound quality is one gram, and active compound gross mass is designated as 1 Part, plus the decocting of 10 times of weight boiled 3 hours, and the decocting of second plus 7 times of weight is boiled 2 hours, will twice decoction liquor with 3 layers of gauze Filtration, merging filtrate concentrates the filtrate to the thick paste that relative density is 1.26-1.36 (50 DEG C), and spray drying obtains dry extract；

Specific experiment

Babesiasis disease horse 27 is chosen in clinic, body weight, age, body condition are identical with comparativity, are randomly divided into 2 groups.

Trial drug：One group of composition oral liquid prepared from the preferred embodiment for the present invention 3, usage and dosage：Stomach tube Dispensing, by horse body weight 3ml/kg, one time a day, is used in conjunction 10 days.Another control group uses flavacridin hydrochloride, and flavacridin hydrochloride can be vein note Penetrate, by per kilogram of body weight 4mg/kg, 1% parenteral solution is made into water for injection, be spaced and inject within 2 days 1 time, share medicine 5 times.

1 composition test group of table and flavacridin hydrochloride control group contrast test

Experiment group	Treatment number	Cure number	Effective number	Recurrence number
					This composition group	12	11	12	0
Flavacridin hydrochloride group	15	13	14	1

Curative effect determinate standard：Criterion of cure：Sick horse body temperature, diet recover normal, mucous membrane xanthochromia, chest oedema disappear, and adopt The sick horse blood smear for microscopic examination result of collection, it is negative.Effective standard：Sick horse body temperature, diet recover normal, mucous membrane xanthochromia mitigates, chest Edema extinction, the sick horse blood smear for microscopic examination result of collection is positive.Null criterion：Clinical symptoms have no any change, the sick horse of collection Blood smear microscopy result, it is positive.

Experiment is as can be seen that Chinese medicine composition of the invention compared to control group drug effect substantially, is tied over the course for the treatment of above Close modern inspection technology and verified that determined curative effect, clinical practice is without any side effects.

Experiment case：Certain raising family is reacted, and has 3 recent anorexias of sick horse in family, and spirit is depressed, and carcass is become thin.

Clinical examination and diagnosis：Sick horse spirit is depressed, anorexia, and conjunctiva xanthochromia has Anemia, and chest has slight water Swollen, 3 sick horse body temperature are increased to 39.3-39.8 DEG C, in batch-type heat type, breathe per minute 17-20/ times, and pulse is per minute 45-49/ times, find that issuing existing tens of ticks in sick horse armpit bites in clinical examination, inquiry stores main local prevalence medical history simultaneously With reference to clinical examination, observed in sick Horse Neck venous blood collection with venesection observation, color is light red, blood is in thin aqueous Shape, stickiness is slightly worse, and tentative diagnosis is equine piroplasmosis, the sick horse have sharp ears position blood of collection, is dyeed with Ji's nurse Sa after smear, and microscopy is seen Examine has multiple either large or small burnt worm polypides in a visual field, is finally diagnosed as babesiasis.

Treatment：The composition pulvis prepared with this preferred embodiment 2, by horse body weight 3g/kg, washes stirring open equal with boiling water Even Hou Wen is offerd medicine with stomach tube, once a day, is used in conjunction 8 days；After medication after 6 days, sick horse body temperature recovers in normal value, spirit improvement, Start a small amount of green forage of searching for food；10 days sick horse chest oedema disappear after medication, and conjunctiva xanthochromia goes down, and in clear baby pink, uses Medicine gives the disease horse congee soup that black bean powder is boiled after terminating, to strengthen nutrition improvement Anemia, recover thin and weak constitution, after 15 days Take disease horse have sharp ears venous blood and make smear, checked under the microscope with Ji's nurse Sa decoration method, have no burnt worm polypide, follow-up after January Store main no relapse.

Claims

1. a kind of Chinese medicine composition for treating the western babesiasis of horse BABEI, it is characterised in that constituted by following weight portion：Kuh-seng 40- 65 parts, sweet wormwood 40-60 parts, subdigitate wormwood herb 40-60 parts, madder 40-60 parts, Semi-pinnated Brake Herb 30-50 parts, barberry 40-60 parts, ginger process Huang Even 10-30 parts, dutchmanspipe root 40-60 parts, Amomum cardamomum 20-40 parts, safflower 5-20 parts, 25-45 parts of salt stir-baked FRUCTUS TSAOKO, conic gymnadenia tuber 90- 110 parts, 20-40 parts of umbrella handle kiss-me, honey process the root of straight ladybell 40-60 parts, Radix Glycyrrhizae (processed with honey) 15-30 parts.

2. it is according to claim 1 treatment the western babesiasis of horse BABEI Chinese medicine composition, it is characterised in that by following weight Part composition：40 parts of kuh-seng, 40 parts of sweet wormwood, 40 parts of subdigitate wormwood herb, 40 parts of madder, 30 parts of Semi-pinnated Brake Herb, 40 parts of barberry, ginger process the coptis 10 Part, 40 parts of dutchmanspipe root, 20 parts of Amomum cardamomum, 5 parts of safflower, 25 parts of salt stir-baked FRUCTUS TSAOKO, 90 parts of conic gymnadenia tuber, 20 parts of umbrella handle kiss-me, honey Process 40 parts of the root of straight ladybell, 15 parts of Radix Glycyrrhizae (processed with honey).

3. it is according to claim 1 treatment the western babesiasis of horse BABEI Chinese medicine composition, it is characterised in that by following weight Part composition：65 parts of kuh-seng, 60 parts of sweet wormwood, 60 parts of subdigitate wormwood herb, 60 parts of madder, 50 parts of Semi-pinnated Brake Herb, 60 parts of barberry, ginger process the coptis 30 Part, 60 parts of dutchmanspipe root, 40 parts of Amomum cardamomum, 20 parts of safflower, 45 parts of salt stir-baked FRUCTUS TSAOKO, 110 parts of conic gymnadenia tuber, 40 parts of umbrella handle kiss-me, Honey processs 60 parts of the root of straight ladybell, 30 parts of Radix Glycyrrhizae (processed with honey).

4. it is according to claim 1 treatment the western babesiasis of horse BABEI Chinese medicine composition, it is characterised in that by following weight Part composition：43 parts of kuh-seng, 42 parts of sweet wormwood, 43 parts of subdigitate wormwood herb, 44 parts of madder, 32 parts of Semi-pinnated Brake Herb, 43 parts of barberry, ginger process the coptis 12 Part, 43 parts of dutchmanspipe root, 22 parts of Amomum cardamomum, 7 parts of safflower, 28 parts of salt stir-baked FRUCTUS TSAOKO, 93 parts of conic gymnadenia tuber, 23 parts of umbrella handle kiss-me, honey Process 42 parts of the root of straight ladybell, 17 parts of Radix Glycyrrhizae (processed with honey).

5. it is according to claim 1 treatment the western babesiasis of horse BABEI Chinese medicine composition, it is characterised in that by following weight Part composition：45 parts of kuh-seng, 44 parts of sweet wormwood, 46 parts of subdigitate wormwood herb, 47 parts of madder, 35 parts of Semi-pinnated Brake Herb, 45 parts of barberry, ginger process the coptis 15 Part, 46 parts of dutchmanspipe root, 24 parts of Amomum cardamomum, 9 parts of safflower, 30 parts of salt stir-baked FRUCTUS TSAOKO, 96 parts of conic gymnadenia tuber, 25 parts of umbrella handle kiss-me, honey Process 45 parts of the root of straight ladybell, 19 parts of Radix Glycyrrhizae (processed with honey).

6. it is according to claim 1 treatment the western babesiasis of horse BABEI Chinese medicine composition, it is characterised in that by following weight Part composition：49 parts of kuh-seng, 48 parts of sweet wormwood, 49 parts of subdigitate wormwood herb, 48 parts of madder, 37 parts of Semi-pinnated Brake Herb, 48 parts of barberry, ginger process the coptis 18 Part, 49 parts of dutchmanspipe root, 27 parts of Amomum cardamomum, 11 parts of safflower, 33 parts of salt stir-baked FRUCTUS TSAOKO, 98 parts of conic gymnadenia tuber, 29 parts of umbrella handle kiss-me, honey Process 48 parts of the root of straight ladybell, 22 parts of Radix Glycyrrhizae (processed with honey).

7. it is according to claim 1 treatment the western babesiasis of horse BABEI Chinese medicine composition, it is characterised in that by following weight Part composition：52 parts of kuh-seng, 50 parts of sweet wormwood, 51 parts of subdigitate wormwood herb, 50 parts of madder, 40 parts of Semi-pinnated Brake Herb, 50 parts of barberry, ginger process the coptis 21 Part, 52 parts of dutchmanspipe root, 29 parts of Amomum cardamomum, 13 parts of safflower, 38 parts of salt stir-baked FRUCTUS TSAOKO, 100 parts of conic gymnadenia tuber, 32 parts of umbrella handle kiss-me, Honey processs 50 parts of the root of straight ladybell, 24 parts of Radix Glycyrrhizae (processed with honey).

8. it is according to claim 1 treatment the western babesiasis of horse BABEI Chinese medicine composition, it is characterised in that by following weight Part composition：54 parts of kuh-seng, 52 parts of sweet wormwood, 53 parts of subdigitate wormwood herb, 52 parts of madder, 42 parts of Semi-pinnated Brake Herb, 53 parts of barberry, ginger process the coptis 23 Part, 54 parts of dutchmanspipe root, 31 parts of Amomum cardamomum, 15 parts of safflower, 42 parts of salt stir-baked FRUCTUS TSAOKO, 102 parts of conic gymnadenia tuber, 34 parts of umbrella handle kiss-me, Honey processs 52 parts of the root of straight ladybell, 26 parts of Radix Glycyrrhizae (processed with honey).

9. it is according to claim 1 treatment the western babesiasis of horse BABEI Chinese medicine composition, it is characterised in that by following weight Part composition：56 parts of kuh-seng, 54 parts of sweet wormwood, 55 parts of subdigitate wormwood herb, 54 parts of madder, 45 parts of Semi-pinnated Brake Herb, 56 parts of barberry, ginger process the coptis 26 Part, 56 parts of dutchmanspipe root, 35 parts of Amomum cardamomum, 17 parts of safflower, 43 parts of salt stir-baked FRUCTUS TSAOKO, 105 parts of conic gymnadenia tuber, 36 parts of umbrella handle kiss-me, Honey processs 54 parts of the root of straight ladybell, 28 parts of Radix Glycyrrhizae (processed with honey).

10. it is according to claim 1 treatment the western babesiasis of horse BABEI Chinese medicine composition, it is characterised in that by following heavy Amount part composition：58 parts of kuh-seng, 56 parts of sweet wormwood, 57 parts of subdigitate wormwood herb, 58 parts of madder, 48 parts of Semi-pinnated Brake Herb, 58 parts of barberry, ginger process the coptis 28 parts, 58 parts of dutchmanspipe root, 38 parts of Amomum cardamomum, 19 parts of safflower, 44 parts of salt stir-baked FRUCTUS TSAOKO, 108 parts of conic gymnadenia tuber, umbrella handle kiss-me 38 Part, honey process 56 parts of the root of straight ladybell, 24 parts of Radix Glycyrrhizae (processed with honey).