CN107596279A - A kind of medicine for treating cerebral apoplexy sequela and senile dementia and preparation method thereof - Google Patents
A kind of medicine for treating cerebral apoplexy sequela and senile dementia and preparation method thereof Download PDFInfo
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Abstract
The present invention relates to a kind of medicine for treating cerebral apoplexy sequela and senile dementia, processed using natural Chinese medicinal herb reasonable compatibility and science, reach Zishen fill fine, support it and very latent receive convergence；Invigorate the spleen and benefit qi, reach yang-energy, calming wind and dredging collateral along its property liter；Its is dropped turbid to allay excitement with the expectoration stasis of blood, inducing resuscitation, nourishing heart.Reach yin and yang in equilibrium, the five internal organs are gentle.Available for nerve, spirit, mental handicape disease.To hemiplegia, paraplegia, facial paralysis, aphasis, dysphagia, cognitive disorder, be urinary and fecal inconvenience, slow-witted of expression, intelelectual deterioration, memory loss is miscalculated and mental symptom, depression, headache, insomnia, epilepsy etc. have a good preventive and therapeutic effect, clinical treatment effective percentage is up to more than 90%.For medicine by processing, lipophilicity increase, active ingredient readily penetrates through the blood-brain barrier of class lipid bilayer composition, plays targeted therapy effect, quick release active ingredient, plays biological effect, raising evident in efficacy.
Description
Technical field
The invention belongs to pharmaceutical technology field, and in particular to a kind of medicine for treating cerebral apoplexy sequela and senile dementia and
Its preparation method.
Background technology
Senile dementia means the various dementias occurred in the senescence phase, including Alzheimer disease (also known as senilism
Property dull-witted, Alzheimer ' s disease, AD), vascular dementia (Vascular dementia, D), Mixed dementia.With
The retrogression pathological changes of brain, brain cell atrophy are the dull-witted syndrome of its pathologic basis.And AD is managed by ischemic, hemorrhagic encephalopathic more
Triggering, symptom and neurobiochemistry feature are often interlaced overlapping, and people had once done many work and gone to differentiate AD and VD, but
With deepening continuously for research, similitude between the two and both may be in itself plyability increasingly by people's weight
Depending on.They clinically show as the decrease of memory caused by cognitive decrease, and behavior is slow, exercise not harmony.It is led
The pathological characters wanted are that intracerebral a large amount of senile plaque expellings, neurofibrillary tangles, amyloid-beta deposition and neuron vacuole occurs
Denaturation and a large amount of forfeitures.
With the continuous development of modern medicine, there are some medicines, though relieving the illness of many patients, majority faces
Bed doctor and patient still feels slowly effect, weak curative effect, medicine time is long, costly, treatment face is single, the symptom related to the disease
Treatment can not be taken into account with sign.
The content of the invention
In order to solve above mentioned problem existing for prior art, the invention provides one kind to treat cerebral apoplexy sequela and old age
Dull-witted medicine and preparation method thereof.
The technical solution adopted in the present invention is：
A kind of medicine for treating cerebral apoplexy sequela and senile dementia, raw material components include：
Radix Astragali 20-30 parts by weight, ginseng 5-10 parts by weight, aizoon stonecrop 10-12 parts by weight, red sage root 10-15 parts by weight, when
Return tail 10-15 parts by weight, cultivated land 20-30 parts by weight, Fructus Corni 12-20 parts by weight, saline cistanche 10-15 parts by weight, keel 10-15
Parts by weight, tortoiseshell 10-15 parts by weight, calamus 10-12 parts by weight, polygala 10-12 parts by weight, tuber of pinellia 8-10 parts by weight, rhizoma Gastrodiae 6-9
Parts by weight, yncaria stem with hooks 10-15 parts by weight, arisaema cum bile 8-10 parts by weight, Common St.Paulswort Herb 15-30 parts by weight, centipede 1-3 parts by weight, the root of kudzu vine
6-9 parts by weight, radix glycyrrhizae 6-9 parts by weight, root of bidentate achyranthes 6-9 parts by weight, root tuber of aromatic turmeric 10-15 parts by weight, dry Chinese olive 6-12 parts by weight, Fructus Dipsaci
25-35 parts by weight and golden cicada flower 5-9 parts by weight.
The raw material components of further preferably described treatment cerebral apoplexy sequela and medicine for senile dementia include：
Radix Astragali 22-28 parts by weight, ginseng 6-9 parts by weight, aizoon stonecrop 10.5-11.5 parts by weight, red sage root 12-13 weight
Part, Radix Angelicae Sinensis tail 12-13 parts by weight, cultivated land 22-28 parts by weight, Fructus Corni 14-18 parts by weight, saline cistanche 12-13 parts by weight, keel
12-13 parts by weight, tortoiseshell 12-13 parts by weight, calamus 10.5-11.5 parts by weight, polygala 10.5-11.5 parts by weight, tuber of pinellia 8.5-
9.5 parts by weight, rhizoma Gastrodiae 7-8 parts by weight, yncaria stem with hooks 12-13 parts by weight, arisaema cum bile 8.5-9.5 parts by weight, Common St.Paulswort Herb 22-23 weight
Part, centipede 1.5-2.5 parts by weight, root of kudzu vine 7-8 parts by weight, radix glycyrrhizae 7-8 parts by weight, root of bidentate achyranthes 7-8 parts by weight, root tuber of aromatic turmeric 12-13 weight
Part, dry Chinese olive 8-10 parts by weight, Fructus Dipsaci 28-32 parts by weight and golden cicada flower 6-8 parts by weight.
The raw material components of further preferably described treatment cerebral apoplexy sequela and medicine for senile dementia include：
The parts by weight of the Radix Astragali 25, the parts by weight of ginseng 7.5, the parts by weight of aizoon stonecrop 11, the parts by weight of the red sage root 12.5, Radix Angelicae Sinensis tail 12.5
Parts by weight, the parts by weight of cultivated land 25, the parts by weight of Fructus Corni 16, the parts by weight of saline cistanche 12.5, the parts by weight of keel 12.5, the weight of tortoiseshell 12.5
Measure part, the parts by weight of calamus 11, the parts by weight of polygala 11, the parts by weight of the tuber of pinellia 9, the parts by weight of rhizoma Gastrodiae 7.5, the parts by weight of yncaria stem with hooks 12.5, courage south
The parts by weight of 9 parts by weight, Common St.Paulswort Herbs of star 22.5, the parts by weight of centipede 2, the parts by weight of the root of kudzu vine 7.5, the parts by weight of radix glycyrrhizae 7.5, the weight of the root of bidentate achyranthes 7.5
Amount part, the parts by weight of root tuber of aromatic turmeric 12.5, the parts by weight of dry Chinese olive 9, the parts by weight of Fructus Dipsaci 30 and golden cicada spend 7 parts by weight.
The preparation method of the treatment cerebral apoplexy sequela and medicine for senile dementia, comprises the following steps：
(1) olive oil and sesame oil are weighed, be sufficiently mixed it is uniform and boiled, first add centipede fry to sallow crisp taking-up, obtain
Rear centipede is processed to stir-fry；Keel and tortoiseshell are added again, add cultivated land, Fructus Corni, root of bidentate achyranthes, Common St.Paulswort Herbs and saline cistanche later, together
Fry to sallow taking-up, obtain stir-fry and process rear keel, fry and process rear tortoiseshell, fry and process rear cultivated land, fry and process rear Fructus Corni, fry and process the rear root of bidentate achyranthes, stir-fry
Rear saline cistanche is processed in Zhi Hou Common St.Paulswort Herbs and stir-fry；
(2) addition residual drug component in rear medicine is processed in the stir-fry obtained to step (1), is sufficiently mixed uniformly, is added water to carry out
Decoct, obtain decoction liquor；
(3) step (2) described decoction liquor is filtered successively, concentrated, obtain the concentration that relative density is 1.1-1.3
Thing, the concentrate is dried, crushed, produce the medicine of the treatment cerebral apoplexy sequela and senile dementia.
In step (1), the volume ratio of the olive oil and sesame oil is 1-2:1-2.
In step (1), after adding keel and tortoiseshell 1-2min, add the cultivated land, Fructus Corni, root of bidentate achyranthes, Common St.Paulswort Herbs and
Saline cistanche.
In step (2), the decoction repeats three times, the decoction of gained three times to be merged, produces the decoction liquor.
2-8 times that amount of water processs rear medicine gross weight for stir-fry is decocted every time, and the time decocted every time is 30-60min.
In step (3), the temperature for carrying out the concentration is 70-90 DEG C.
The temperature for carrying out the drying is 110-130 DEG C, and the time for carrying out the drying is 0.5-1.5h.
For the ease of understanding the present invention, the raw material in the present invention and drug effect are further elaborated below.
The Radix Astragali, slightly warm in nature are sweet.Invigorating qi for strengthening superficies, diuresis, pus draining and toxin expelling, myogenic.Treat shortness of breath palpitations, it is weak, collapse,
Spontaneous perspiration, night sweat, physically weak edema, chronic nephritis, chronic diarrhea, prolapse of the anus, the prolapse of uterus, ulcer is difficult to burst, the long disunion of the open sore part, children's branch gas
Pipe asthma, chronic hepatitis B, chronic nephritis and vital myocarditis.Use, hidroschesis, diuresis, pus draining and toxin expelling myogenic are preferably processed in tonifying Qi
Preferably give birth to use.
Ginseng, warm-natured, sweet, slight bitter.Reinforce vital energy, veins takes off admittedly, reinforce the spleen to benefit the lung, be promoting production of body fluid and inducing sedation of the mind.Treat it is physically weak to be taken off,
Dyspnea with shortness of breath, spontaneous perspiration limb are cold, tired mind, deficiency of food are vomited and diarrhoea, the deficiency of vital energy is breathed heavily or chronic cough, body fluid deficiency are thirsty, quench one's thirst, insomnia and dreamful sleep, shy
Throb with fear forgetful, impotence, frequent micturition, the disease of all qi-blood-body fluid deficiencies.
Aizoon stonecrop, it is mild-natured, it is sweet, slightly sour.Dissipate stasis of blood hemostasis, analgesia of calming the nerves.For thrombocytopenic purpura, bleeding from five sense organs or subcutaneous tissue,
Haematemesis, spitting of blood, bleeding gums, hemorrhage of digestive tract, uterine hemorrhage, and palpitaition, irritated insomnia；Traumatic injury, wound are controlled in external application
Bleeding, burn and scald.
The red sage root, cold nature, bitter.Stasis-dispelling and pain-killing, promoting blood circulation dysmenorrhoea, relieving restlessness that clears away heart-fire.With controlling irregular menstruation, closed dysmenorrhea, Disorder
Lump in the abdomen accumulation, chest and abdomen shouting pain, hot numbness pain, sore swollen toxin, dysphoria and insomnia；Hepatosplenomegaly, angina pectoris.
Radix Angelicae Sinensis tail, Radix Angelicae Sinensis tail are good at blood-breaking, there is the effect of promoting blood circulation and removing blood stasis, are usually used in treating obstructed Amenorrhea, arthralgia and myalgia, hand
The disease such as foot numbness and the stagnant swelling and pain of hemostasis.
Cultivated land, slightly warm in nature are sweet.Enrich blood enriching yin, beneficial to spirit and marrow.For blood deficiency chlorosis, palpitation and severe palpitation, irregular menstruation, collapse
Leak down blood, the deficiency of liver-yin and kidney-yin, soreness and weakness of waist and knees, osteopyrexia and fever, night sweat seminal emission, Heat Diabetes, dizziness, tinnitus, poliosis.
Fructus Corni, slightly warm in nature are sour, puckery.Tonify the liver and kidney, arresting collape syndrome by astringents.For dizziness ear toot, soreness of waist and knee joint, impotence is lost
Essence, enuresis frequent micturition, under uterine bleeding band, profuse sweating collapse, Heat Diabetes.
Saline cistanche, it is warm-natured, it is sweet, salty.Kidney-replenishing, benefiting essence-blood, relax bowel.For waist knee impotence, impotence, woman not
Pregnant, dry constipation of intestines.
Keel, it is mild-natured, it is sweet, puckery.Tranquillizing the mind by relieving convulsion, arrest sweating controlling nocturnal emission with astringent drugs, stop blooding puckery intestines, myogenic sore.It is demented to control frightened epilepsy, palpitation
Forgetful, insomnia and dreamful sleep, spontaneous sweating, stranguria with turbid discharge of passing out semen, hematemesis is had blood in stool, and under uterine bleeding band, rush down dysentery prolapse of the anus, ulcer does not close up long.
Tortoiseshell, it is cold in nature, it is sweet, salty.Nourishing and suppressing Yang, replenishing kidney and strengthening bone, blood-nourishing bushing.For having a dizzy spell, hectic fever due to yin labor heat, waist
Knees soreness, insomnia of palpitating with fear.
Calamus, slightly warm in nature, acrid flavour, hardship.Have one's ideas straightened out, slit phlegm, qi-regulating, promoting blood circulation, dissipate wind, dry.With controlling epilepsy, coma due to blocking of the respiratory system, pyreticosis
Coma, forgetful, deafness with qi stagnation, ambition unhappiness, stomachache, stomachache, wind-cold-dampness arthralgia, swollen ulcer drug, traumatic injury etc..
Polygala, it is warm-natured, it is bitter, pungent.Tranquilize the mind and promote the intelligence, eliminating the phlegm, detumescence.With controlling insomnia and dreamful sleep caused by breakdown of the normal physiological coordination between the heart and the kidney, forgetful
Palpitation with fear, wandering, expectoration is not well, sore swollen toxin, mastosis.
The tuber of pinellia, warm-natured, acrid flavour are poisonous.Eliminating dampness and eliminating phlegm, stopping nausea and vomiting by lowering the adverse flow of QI, dissolving lump and resolving mass.With controlling wet phlegm and cold drink, vomiting, anti-
Stomach, cough and phlegm, fullness in chest, phlegm and headache, dizziness and sleepless etc..
Rhizoma Gastrodiae, it is mild-natured, it is sweet.Suppressing hyperactive liver for calming endogenous wind stops convulsion.With control dizziness of having a headache, extremity numbness, child convulsion, epilepsy clonus,
Lockjaw.
Yncaria stem with hooks, it is cool in nature, it is sweet.The flat liver of heat-clearing, dispelling wind and relieving convulsion.With control dizziness of having a headache, faint from fear twitch, pre-eclampsia and high blood
Press disease.
Arisaema cum bile, cool in nature, bitter, micro-pungent.Clearing heat and eliminating phlegm, dispelling wind and relieving convulsion.With controlling phlegm-heat cough, cough up phlegm yellow thick, apoplexy, insane
Epilepsy.
Common St.Paulswort Herb, cold in nature, acrid flavour, hardship.Wind-damp dispelling, sharp joint, removing toxic substances.With arthralgia pain due to rheumatism is controlled, muscles and bones is powerless, waist and knee acid
It is soft, quadriplegia, hemiplegia, rubella wet sore.
Centipede, warm-natured, acrid flavour.Ceases wind antispastic, removes obstruction in channels to relieve pain, dispersing pathogen accumulation.For liver wind agitation, spasm twitch, children
Infantile convulsion, middle air portHemiplegia, lockjaw, rheumatoid arthritis stubborn, migraine and general headache, sore, scrofula, snake bite and insect sting.
The root of kudzu vine, it is cool in nature, it is sweet, pungent.Expelling pathogenic factors from muscles and skin is brought down a fever, promoted the production of body fluid, promoting eruption, Shengyang Zhixie.With cure the wound it is cold, warm headache Xiang Qiang,
Dysphoria with smothery sensation is quenched one's thirst, diarrhea, dysentery, ecchymosis are impermeable, hypertension, angina pectoris, deafness etc..
Radix glycyrrhizae, it is mild-natured, it is sweet.Invigorate the spleen and benefit qi, cough-relieving apophlegmatic, emergency analgesic therapy, mediation property of medicine.Treat weakness of the spleen and the stomach, middle gas
Contraction suddenly has a pain, relaxes that medicine is strong, antidote is malicious in deficiency, cough and asthma, skin sore, abdomen.Heat-clearing should give birth to use, and bowl spares is preferably processed
With.
The root of bidentate achyranthes, mild-natured, bitter, acid.Filling liver kidney, strengthening the bones and muscles, dispelling stasis of blood and stimulating the menstrual flow, ensuring proper downward flow of the blood.With control soreness of waist and knee joint, muscles and bones without
Power, Jing Bi Disorder lumps in the abdomen, dizziness due to hyperactivity of liver-YANG.
Root tuber of aromatic turmeric, cold in nature, acrid flavour, hardship.Promoting blood circulation and stopping pain, promoting the circulation of qi scabies, heart fire-clearing upset-relieving, normalizing gallbladder to cure jaundice.With controlling through closing dysmenorrhoea, heat
Sick coma, epilepsy are gone mad, jaundice, chest and abdomen swelling and pain, shouting pain.
Dry Chinese olive, it is mild-natured, it is sweet, sour.Heat-clearing, relieving sore-throat, promote the production of body fluid, detoxify.With controlling in abscess of throat, cough, polydipsia, ichthyophagy crab
The diseases such as poison.
Fructus Dipsaci, slightly warm in nature, acrid flavour, hardship.Promoting lactation, diuresis, blood circulation promoting competent silt.Alactation is cured mainly, difficult urination, is fallen
Play damage, pain caused by ecchymoma, scrotum swelling and pain.
Golden cicada is spent, cold in nature, sweet, nontoxic.Dispelling wind and heat from the body, promoting eruption, relieving convulsion and spasm, removing nebula；Affection of exogenous wind-heat is cured mainly, is sent out
Heat, dizzy, child convulsion, red eye, swell pain, pharyngalgia, single board computer rash initial stage, rash go out not smooth, pterygium, the morbid night crying of babies.
Oils used is olive oil, pioneering for the present invention applied to headstroke and senile dementia patients.Wherein olive oil institute
The omega-fatty acid contained can increase nitrogen oxide, and the content of this important chemical substance, can relax artery, so as to prevent because of height
Arterial injury caused by blood pressure.Other omega-fatty acid can also prevent the formation of clot in terms of two.First, it can be reduced
Hematoblastic stickiness, blood platelet is allowed to be not easy to be intertwined with fibrinogen；Secondly, omega-fatty acid can reduce fiber egg
White former amount, is also considerably reduced thrombotic probability, improves the blood circulation of brain tissue.Olive oil is rich in single insatiable hunger
And aliphatic acid, it is exactly oleic acid.It can increase HDL-C, and a kind of good courage flowed in our blood is consolidated
Alcohol, and reduce bad cholesterol.Olive oil also contains vitamin A, vitamin B, vitamin D, vitamin E, vitamin K and antioxygen
Compound etc..Olive oil is considered as the oil that human nutrition is best suitable in the grease found so far.
Sesame oil contains the unrighted acids such as very abundant linoleic acid, palmitic acid, easily decomposes absorption and profit by human body
With, to promote the metabolism of cholesterol, and the deposit contributed in elimination arterial blood tube wall.
It is also pioneering to spend treatment headstroke and senile dementia using golden cicada, and golden cicada flower is the medicine for treating tumour and nephrosis,
Find that it has calm, analgesia, syngignoscism to patient in clinical practice, because thering is identical component to have benefit to patient with cordyceps sinensis
Benefit, health care, immunity, and cheap practicality are improved, so quoting it.
The application of two medicines of the root of kudzu vine and the root of bidentate achyranthes adds activity to whole prescription, and main liter of temper of the root of kudzu vine, root of bidentate achyranthes priming enter kidney,
One on the other, sun rises cloudy drop, air transhipment, gas row then blood, the blood then stasis of blood, improves blood circulation, plays half work(of getting over
Effect again.
It is the in love product of flesh and blood to medicine tortoiseshell and keel, the thing of intelligence.The former enters kidney, the latter's enter liver, and dragon rises tortoise and dived, deeply
Brain, more have centipede tying-in nowhere less than, it is up to process rear bearing medicine, is more easy to penetrate blood-brain barrier, reaches the purpose of targeted therapy, therefore
Ancients with red name in the holy pillow in hole it, to show that its effect is out of the ordinary.
Beneficial effects of the present invention are：
The medicine for the treatment of cerebral apoplexy sequela and senile dementia of the present invention, uses a variety of natural Chinese medicinal herbs as raw material
And carry out reasonable compatibility and science and process, the medicine being prepared can Zishen fill fine, support its it is very latent receive convergence, invigorate the spleen and benefit qi,
Risen along its property and reach yang-energy, calming wind and dredging collateral, drop its it is turbid allayed excitement with the expectoration stasis of blood, inducing resuscitation, nourishing heart, reach yin and yang in equilibrium, the five internal organs are put down
With.Available for nerve, spirit, mental handicape disease such as cerebral apoplexy sequela, senile dementia, development in children be slow, hyperactivity,
Many diseases such as epilepsy, headache, insomnia, anxiety, depression, to hemiplegia, paraplegia, facial paralysis, aphasis, dysphagia, recognize
Know obstacle, be urinary and fecal inconvenience, slow-witted of expression, intelelectual deterioration, memory loss is miscalculated and mental symptom, depression, headache, insomnia, epilepsy etc. have
Good preventive and therapeutic action, clinic prove that therapeutic effect is notable, efficient up to more than 90%.The present invention by centipede,
Keel, tortoiseshell and enter renal drug thing cultivated land, Fructus Corni, root of bidentate achyranthes, Common St.Paulswort Herbs and saline cistanche carry out oil and process method processing, increase medicine
The fat-soluble and precipitation of active ingredient, effective ingredient is readily penetrated through the blood-brain barrier of class lipid bilayer composition, play
The effect of targeted therapy, and quick release active ingredient, biological effect is played, improve the treatment for the treatment of headstroke and senile dementia
Effect.The present invention solves general medicine and hardly enters blood-brain barrier, it is impossible to plays the knotty problem of drug effect.
Embodiment
To make the object, technical solutions and advantages of the present invention clearer, technical scheme will be carried out below
Detailed description.Obviously, described embodiment is only part of the embodiment of the present invention, rather than whole embodiments.Base
Embodiment in the present invention, those of ordinary skill in the art are resulting on the premise of creative work is not made to be owned
Other embodiment, belong to the scope that the present invention is protected.
In example below 1g is represented with 1 parts by weight.
Embodiment 1
The present embodiment provides a kind of medicine for treating cerebral apoplexy sequela and senile dementia, and raw material components include：
The parts by weight of the Radix Astragali 20, the parts by weight of ginseng 10, the parts by weight of aizoon stonecrop 10, the parts by weight of the red sage root 15, the weight of Radix Angelicae Sinensis tail 10
Part, the parts by weight of cultivated land 30, the parts by weight of Fructus Corni 12, the parts by weight of saline cistanche 15, the parts by weight of keel 10, the parts by weight of tortoiseshell 15, calamus
10 parts by weight, the parts by weight of polygala 12, the parts by weight of the tuber of pinellia 8, the parts by weight of rhizoma Gastrodiae 9, the parts by weight of yncaria stem with hooks 10, the parts by weight, pig of arisaema cum bile 10
It is 15 parts by weight of Xian grass, the parts by weight of centipede 3, the parts by weight of the root of kudzu vine 6, the parts by weight of radix glycyrrhizae 9, the parts by weight of the root of bidentate achyranthes 6, the parts by weight of root tuber of aromatic turmeric 15, dry
The parts by weight of Chinese olive 6, the parts by weight of Fructus Dipsaci 35 and golden cicada spend 5 parts by weight.
Wherein Fructus Dipsaci is crushes after stir-fry, in favor of the release of active ingredient.
Further, the present embodiment provides the preparation method of the treatment cerebral apoplexy sequela and medicine for senile dementia, including
Following steps：
(1) it is 1 according to volume ratio:1 weighs olive oil and sesame oil, respectively olive oil 100ml, and sesame oil 100ml is fully mixed
Close it is uniform and boiled, first add centipede fry to sallow crisp taking-up, obtain stir-fry and process rear centipede；Keel and tortoiseshell are added again,
Cultivated land, Fructus Corni, root of bidentate achyranthes, Common St.Paulswort Herbs and saline cistanche are added after 1min, is fried together to sallow crisp taking-up, obtains dragon after stir-fry is processed
Bone, rear tortoiseshell is processed in stir-fry, rear cultivated land is processed in stir-fry, rear Fructus Corni is processed in stir-fry, the rear root of bidentate achyranthes is processed in stir-fry, rear Common St.Paulswort Herb is processed in stir-fry and rear saline cistanche is processed in stir-fry；
(2) addition residual drug component in rear medicine is processed in the stir-fry obtained to step (1), is sufficiently mixed uniformly, is added 2 times of matter
Amount water carries out decoction 60min, obtains decoction liquor；
(3) step (2) described decoction liquor is filtered successively, 70 DEG C concentration, until obtain relative density be 1.1 it is dense
Contracting thing, by the concentrate after 110 DEG C are dried 1.5h, it is 80 mesh to be crushed to particle diameter, after producing the treatment headstroke
Lose the medicine of disease and senile dementia.
Embodiment 2
The present embodiment provides a kind of medicine for treating cerebral apoplexy sequela and senile dementia, and raw material components include：
The parts by weight of the Radix Astragali 30, the parts by weight of ginseng 5, the parts by weight of aizoon stonecrop 12, the parts by weight of the red sage root 10, the weight of Radix Angelicae Sinensis tail 15
Part, the parts by weight of cultivated land 20, the parts by weight of Fructus Corni 20, the parts by weight of saline cistanche 10, the parts by weight of keel 15, the parts by weight of tortoiseshell 10, calamus
12 parts by weight, the parts by weight of polygala 10, the parts by weight of the tuber of pinellia 10, the parts by weight of rhizoma Gastrodiae 6, the parts by weight of yncaria stem with hooks 15, the parts by weight, pig of arisaema cum bile 8
It is 30 parts by weight of Xian grass, the parts by weight of centipede 1, the parts by weight of the root of kudzu vine 9, the parts by weight of radix glycyrrhizae 6, the parts by weight of the root of bidentate achyranthes 9, the parts by weight of root tuber of aromatic turmeric 10, dry
The parts by weight of Chinese olive 12, the parts by weight of Fructus Dipsaci 25 and golden cicada spend 9 parts by weight.
Wherein Fructus Dipsaci is crushes after stir-fry, in favor of the release of active ingredient.
Further, the present embodiment provides the preparation method of the treatment cerebral apoplexy sequela and medicine for senile dementia, including
Following steps：
(1) it is 1 according to volume ratio:2 weigh olive oil and sesame oil, respectively olive oil 50ml, and sesame oil 100ml is fully mixed
Close it is uniform and boiled, first add centipede fry to sallow crisp taking-up, obtain stir-fry and process rear centipede；Keel and tortoiseshell are added again,
Cultivated land, Fructus Corni, root of bidentate achyranthes, Common St.Paulswort Herbs and saline cistanche are added after 2min, is fried together to sallow taking-up, is obtained stir-fry and process rear keel, stir-fry
Process rear tortoiseshell, rear cultivated land is processed in stir-fry, rear Fructus Corni is processed in stir-fry, the rear root of bidentate achyranthes is processed in stir-fry, rear Common St.Paulswort Herb is processed in stir-fry and rear saline cistanche is processed in stir-fry；
(2) addition residual drug component in rear medicine is processed in the stir-fry obtained to step (1), is sufficiently mixed uniformly, is added 8 times of matter
Amount water carries out decoction 30min, obtains decoction liquor；
(3) step (2) described decoction liquor is filtered successively, 90 DEG C concentration, until obtain relative density be 1.3 it is dense
Contracting thing, by the concentrate after 130 DEG C are dried 0.5h, it is 120 mesh to be crushed to particle diameter, after producing the treatment headstroke
Lose the medicine of disease and senile dementia.
Embodiment 3
The present embodiment provides a kind of medicine for treating cerebral apoplexy sequela and senile dementia, and raw material components include：
The parts by weight of the Radix Astragali 22, the parts by weight of ginseng 9, the parts by weight of aizoon stonecrop 10.5, the parts by weight of the red sage root 13, the weight of Radix Angelicae Sinensis tail 12
Part, the parts by weight of cultivated land 28, the parts by weight of Fructus Corni 14, the parts by weight of saline cistanche 13, the parts by weight of keel 12, the parts by weight of tortoiseshell 13, calamus
10.5 parts by weight, the parts by weight of polygala 11.5, the parts by weight of the tuber of pinellia 8.5, the parts by weight of rhizoma Gastrodiae 7, the parts by weight of yncaria stem with hooks 13, the weight of arisaema cum bile 9.5
Measure the parts by weight of Fen, Common St.Paulswort Herbs 22, the parts by weight of centipede 2.5, the parts by weight of the root of kudzu vine 7, the parts by weight of radix glycyrrhizae 8, the parts by weight of the root of bidentate achyranthes 7, root tuber of aromatic turmeric 13
Parts by weight, the parts by weight of dry Chinese olive 8, the parts by weight of Fructus Dipsaci 32 and golden cicada spend 6 parts by weight.
Wherein Fructus Dipsaci is crushes after stir-fry, in favor of the release of active ingredient.
Further, the present embodiment provides the preparation method of the treatment cerebral apoplexy sequela and medicine for senile dementia, including
Following steps：
(1) it is 2 according to volume ratio:1 weighs olive oil and sesame oil, respectively olive oil 100ml, and sesame oil 50ml is fully mixed
Close it is uniform and boiled, first add centipede fry to sallow crisp taking-up, obtain stir-fry and process rear centipede；Keel and tortoiseshell are added again,
Cultivated land, Fructus Corni, root of bidentate achyranthes, Common St.Paulswort Herbs and saline cistanche are added after 1.5min, is fried together to sallow crisp taking-up, obtains dragon after stir-fry is processed
Bone, rear tortoiseshell is processed in stir-fry, rear cultivated land is processed in stir-fry, rear Fructus Corni is processed in stir-fry, the rear root of bidentate achyranthes is processed in stir-fry, rear Common St.Paulswort Herb is processed in stir-fry and rear saline cistanche is processed in stir-fry；
(2) addition residual drug component in rear medicine is processed in the stir-fry obtained to step (1), is sufficiently mixed uniformly, is added 5 times of matter
Amount water carries out decoction 40min, obtains decoction liquor；
(3) step (2) described decoction liquor is filtered successively, 80 DEG C concentration, until obtain relative density be 1.2 it is dense
Contracting thing, by the concentrate after 120 DEG C are dried 1h, it is 100 mesh to be crushed to particle diameter, is lost after producing the treatment headstroke
Disease and the medicine of senile dementia.
Embodiment 4
The present embodiment provides a kind of medicine for treating cerebral apoplexy sequela and senile dementia, and raw material components include：
The parts by weight of the Radix Astragali 28, the parts by weight of ginseng 6, the parts by weight of aizoon stonecrop 11.5, the parts by weight of the red sage root 12, the weight of Radix Angelicae Sinensis tail 13
Part, the parts by weight of cultivated land 22, the parts by weight of Fructus Corni 18, the parts by weight of saline cistanche 12, the parts by weight of keel 13, the parts by weight of tortoiseshell 12, calamus
11.5 parts by weight, the parts by weight of polygala 10.5, the parts by weight of the tuber of pinellia 9.5, the parts by weight of rhizoma Gastrodiae 7, the parts by weight of yncaria stem with hooks 13, the weight of arisaema cum bile 8.5
Measure the parts by weight of Fen, Common St.Paulswort Herbs 23, the parts by weight of centipede 1.5, the parts by weight of the root of kudzu vine 8, the parts by weight of radix glycyrrhizae 7, the parts by weight of the root of bidentate achyranthes 8, root tuber of aromatic turmeric 12
Parts by weight, the parts by weight of dry Chinese olive 10, the parts by weight of Fructus Dipsaci 28 and golden cicada spend 8 parts by weight.
Wherein Fructus Dipsaci is crushes after stir-fry, in favor of the release of active ingredient.
Further, the present embodiment provides the preparation method of the treatment cerebral apoplexy sequela and medicine for senile dementia, including
Following steps：
(1) it is 1 according to volume ratio:1 weighs olive oil and sesame oil, respectively olive oil 100ml, and sesame oil 100ml is fully mixed
Close it is uniform and boiled, first add centipede fry to sallow crisp taking-up, obtain stir-fry and process rear centipede；Keel and tortoiseshell are added again,
Cultivated land, Fructus Corni, root of bidentate achyranthes, Common St.Paulswort Herbs and saline cistanche are added after 1min, is fried together to sallow crisp taking-up, obtains dragon after stir-fry is processed
Bone, stir-fry process rear tortoiseshell, fry process rear cultivated land, fry process rear Fructus Corni fry process the rear root of bidentate achyranthes, rear Common St.Paulswort Herb is processed in stir-fry and rear saline cistanche is processed in stir-fry；
(2) addition residual drug component in rear medicine is processed in the stir-fry obtained to step (1), is sufficiently mixed uniformly, is added 5 times of matter
Amount water carries out decoction 40min, obtains decoction liquor；
(3) step (2) described decoction liquor is filtered successively, 80 DEG C concentration, until obtain relative density be 1.2 it is dense
Contracting thing, by the concentrate after 120 DEG C are dried 1h, it is 100 mesh to be crushed to particle diameter, is lost after producing the treatment headstroke
Disease and the medicine of senile dementia.
Embodiment 5
The present embodiment provides a kind of medicine for treating cerebral apoplexy sequela and senile dementia, and raw material components include：
The parts by weight of the Radix Astragali 25, the parts by weight of ginseng 7.5, the parts by weight of aizoon stonecrop 11, the parts by weight of the red sage root 12.5, Radix Angelicae Sinensis tail 12.5
Parts by weight, the parts by weight of cultivated land 25, the parts by weight of Fructus Corni 16, the parts by weight of saline cistanche 12.5, the parts by weight of keel 12.5, the weight of tortoiseshell 12.5
Measure part, the parts by weight of calamus 11, the parts by weight of polygala 11, the parts by weight of the tuber of pinellia 9, the parts by weight of rhizoma Gastrodiae 7.5, the parts by weight of yncaria stem with hooks 12.5, courage south
The parts by weight of 9 parts by weight, Common St.Paulswort Herbs of star 22.5, the parts by weight of centipede 2, the parts by weight of the root of kudzu vine 7.5, the parts by weight of radix glycyrrhizae 7.5, the weight of the root of bidentate achyranthes 7.5
Amount part, the parts by weight of root tuber of aromatic turmeric 12.5, the parts by weight of dry Chinese olive 9, the parts by weight of Fructus Dipsaci 30 and golden cicada spend 7 parts by weight.
Wherein Fructus Dipsaci is crushes after stir-fry, in favor of the release of active ingredient.
Further, the present embodiment provides the preparation method of the treatment cerebral apoplexy sequela and medicine for senile dementia, including
Following steps：
(1) it is 1 according to volume ratio:1 weighs olive oil and sesame oil, respectively olive oil 100ml, and sesame oil 100ml is fully mixed
Close it is uniform and boiled, first add centipede fry to sallow crisp taking-up, obtain stir-fry and process rear centipede；Keel and tortoiseshell are added again,
Cultivated land, Fructus Corni, root of bidentate achyranthes, Common St.Paulswort Herbs and saline cistanche are added after 1min, is fried together to sallow taking-up, is obtained stir-fry and process rear keel, stir-fry
Process rear tortoiseshell, rear cultivated land is processed in stir-fry, rear Fructus Corni is processed in stir-fry, the rear root of bidentate achyranthes is processed in stir-fry, rear Common St.Paulswort Herb is processed in stir-fry and rear saline cistanche is processed in stir-fry；
(2) addition residual drug component in rear medicine is processed in the stir-fry obtained to step (1), is sufficiently mixed uniformly, is added 5 times of matter
Amount water carries out decoction 40min, obtains decoction liquor；
(3) step (2) described decoction liquor is filtered successively, 80 DEG C concentration, until obtain relative density be 1.2 it is dense
Contracting thing, by the concentrate after 120 DEG C are dried 1h, it is 100 mesh to be crushed to particle diameter, is lost after producing the treatment headstroke
Disease and the medicine of senile dementia.
The foregoing is only a specific embodiment of the invention, but protection scope of the present invention is not limited thereto, any
Those familiar with the art the invention discloses technical scope in, change or replacement can be readily occurred in, should all be contained
Cover within protection scope of the present invention.Therefore, protection scope of the present invention should be based on the protection scope of the described claims.
Claims (10)
1. a kind of medicine for treating cerebral apoplexy sequela and senile dementia, it is characterised in that raw material components include：
Radix Astragali 20-30 parts by weight, ginseng 5-10 parts by weight, aizoon stonecrop 10-12 parts by weight, red sage root 10-15 parts by weight, Radix Angelicae Sinensis tail
10-15 parts by weight, cultivated land 20-30 parts by weight, Fructus Corni 12-20 parts by weight, saline cistanche 10-15 parts by weight, keel 10-15 weight
Part, tortoiseshell 10-15 parts by weight, calamus 10-12 parts by weight, polygala 10-12 parts by weight, tuber of pinellia 8-10 parts by weight, rhizoma Gastrodiae 6-9 weight
Part, yncaria stem with hooks 10-15 parts by weight, arisaema cum bile 8-10 parts by weight, Common St.Paulswort Herb 15-30 parts by weight, centipede 1-3 parts by weight, root of kudzu vine 6-9 weights
Measure part, radix glycyrrhizae 6-9 parts by weight, root of bidentate achyranthes 6-9 parts by weight, root tuber of aromatic turmeric 10-15 parts by weight, dry Chinese olive 6-12 parts by weight, Fructus Dipsaci 25-35
Parts by weight and golden cicada flower 5-9 parts by weight.
2. the medicine for the treatment of cerebral apoplexy sequela according to claim 1 and senile dementia, it is characterised in that raw material components
Including：
Radix Astragali 22-28 parts by weight, ginseng 6-9 parts by weight, aizoon stonecrop 10.5-11.5 parts by weight, red sage root 12-13 parts by weight, when
Return tail 12-13 parts by weight, cultivated land 22-28 parts by weight, Fructus Corni 14-18 parts by weight, saline cistanche 12-13 parts by weight, keel 12-13
Parts by weight, tortoiseshell 12-13 parts by weight, calamus 10.5-11.5 parts by weight, polygala 10.5-11.5 parts by weight, tuber of pinellia 8.5-9.5 weights
Measure part, rhizoma Gastrodiae 7-8 parts by weight, yncaria stem with hooks 12-13 parts by weight, arisaema cum bile 8.5-9.5 parts by weight, Common St.Paulswort Herb 22-23 parts by weight, centipede
1.5-2.5 parts by weight, root of kudzu vine 7-8 parts by weight, radix glycyrrhizae 7-8 parts by weight, root of bidentate achyranthes 7-8 parts by weight, root tuber of aromatic turmeric 12-13 parts by weight, dry green grass or young crops
Fruit 8-10 parts by weight, Fructus Dipsaci 28-32 parts by weight and golden cicada flower 6-8 parts by weight.
3. the medicine for the treatment of cerebral apoplexy sequela according to claim 1 and senile dementia, it is characterised in that raw material components
Including：
The parts by weight of the Radix Astragali 25, the parts by weight of ginseng 7.5, the parts by weight of aizoon stonecrop 11, the parts by weight of the red sage root 12.5, the weight of Radix Angelicae Sinensis tail 12.5
Part, the parts by weight of cultivated land 25, the parts by weight of Fructus Corni 16, the parts by weight of saline cistanche 12.5, the parts by weight of keel 12.5, the weight of tortoiseshell 12.5
Part, the parts by weight of calamus 11, the parts by weight of polygala 11, the parts by weight of the tuber of pinellia 9, the parts by weight of rhizoma Gastrodiae 7.5, the parts by weight of yncaria stem with hooks 12.5, arisaema cum bile 9
The parts by weight of parts by weight, Common St.Paulswort Herbs 22.5, the parts by weight of centipede 2, the parts by weight of the root of kudzu vine 7.5, the parts by weight of radix glycyrrhizae 7.5, the weight of the root of bidentate achyranthes 7.5
Part, the parts by weight of root tuber of aromatic turmeric 12.5, the parts by weight of dry Chinese olive 9, the parts by weight of Fructus Dipsaci 30 and golden cicada spend 7 parts by weight.
4. the preparation method of any one of the claim 1-3 treatment cerebral apoplexy sequelas and medicine for senile dementia, its feature exist
In comprising the following steps：
(1) olive oil and sesame oil are weighed, be sufficiently mixed it is uniform and boiled, first add centipede fry to sallow crisp taking-up, fried
Process rear centipede；Keel and tortoiseshell are added again, add cultivated land, Fructus Corni, root of bidentate achyranthes, Common St.Paulswort Herbs and saline cistanche later, fry together to
Sallow taking-up, obtain stir-fry process rear keel, fry process rear tortoiseshell, fry process rear cultivated land, fry process rear Fructus Corni, fry process the rear root of bidentate achyranthes, fry process after
Rear saline cistanche is processed in Common St.Paulswort Herb and stir-fry；
(2) addition residual drug component in rear medicine is processed in the stir-fry obtained to step (1), is sufficiently mixed uniformly, is added water to be decocted,
Obtain decoction liquor；
(3) step (2) described decoction liquor is filtered successively, concentrated, obtain the concentrate that relative density is 1.1-1.3, will
The concentrate is dried, crushed, and produces the medicine of the treatment cerebral apoplexy sequela and senile dementia.
5. the preparation method for the treatment of cerebral apoplexy sequela according to claim 4 and medicine for senile dementia, it is characterised in that
In step (1), the volume ratio of the olive oil and sesame oil is 1-2:1-2.
6. the preparation method for the treatment of cerebral apoplexy sequela according to claim 4 and medicine for senile dementia, it is characterised in that
In step (1), after adding keel and tortoiseshell 1-2min, the cultivated land, Fructus Corni, root of bidentate achyranthes, Common St.Paulswort Herbs and saline cistanche are added.
7. the preparation method for the treatment of cerebral apoplexy sequela according to claim 4 and medicine for senile dementia, it is characterised in that
In step (2), the decoction repeats three times, the decoction of gained three times to be merged, produces the decoction liquor.
8. the preparation method for the treatment of cerebral apoplexy sequela according to claim 7 and medicine for senile dementia, it is characterised in that
2-8 times that amount of water processs rear medicine gross weight for stir-fry is decocted every time, and the time decocted every time is 30-60min.
9. the preparation method for the treatment of cerebral apoplexy sequela according to claim 4 and medicine for senile dementia, it is characterised in that
In step (3), the temperature for carrying out the concentration is 70-90 DEG C.
10. the preparation method for the treatment of cerebral apoplexy sequela according to claim 4 and medicine for senile dementia, its feature exist
In the temperature for carrying out the drying is 110-130 DEG C, and the time for carrying out the drying is 0.5-1.5h.
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